CuGenDBv2

Gene ID	PI0005136
Organism	Cucumis metuliferus PI 482460 (Melon (PI 482460) v1)
Description	dCTP pyrophosphatase 1
Genome location	chr02:23524465..23525806
RNA-Seq Expression	PI0005136
Synteny	PI0005136
Gene Ontology terms	GO:0006253 - dCTP catabolic process (biological process) GO:0042262 - DNA protection (biological process) GO:0005829 - cytosol (cellular component) GO:0000287 - magnesium ion binding (molecular function) GO:0047840 - dCTP diphosphatase activity (molecular function)
InterPro domains	IPR025984 - dCTP pyrophosphatase 1

Homology

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GenBank top hits

e value

%identity

Alignment

XP_004138182.1 dCTP pyrophosphatase 1 [Cucumis sativus]

2.2e-63

100

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Query:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFTRALP
        GHAALSKLVKNANKYPVAAFTRALP
Subjt:  GHAALSKLVKNANKYPVAAFTRALP

XP_008453231.1 PREDICTED: dCTP pyrophosphatase 1-like [Cucumis melo]

2.4e-62

98.4

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Query:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFTRALP
        GHAA+SKLVKNANKYPVAA TRALP
Subjt:  GHAALSKLVKNANKYPVAAFTRALP

XP_022921755.1 dCTP pyrophosphatase 1-like [Cucurbita moschata]

4.1e-62

98.4

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Query:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEKTAKDVSLQELRD LAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFTRALP
        GHAALSKLVKNANKYPVAAF RALP
Subjt:  GHAALSKLVKNANKYPVAAFTRALP

XP_022987438.1 dCTP pyrophosphatase 1-like [Cucurbita maxima]

1.6e-61

97.6

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Query:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEKTAKDVSLQELRD L EFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFTRALP
        GHAALSKLVKNANKYPVAAF RALP
Subjt:  GHAALSKLVKNANKYPVAAFTRALP

XP_038880679.1 dCTP pyrophosphatase 1-like [Benincasa hispida]

1.2e-61

97.6

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Query:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        ME+ SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFTRALP
        GHAALSKLVKNANKYPVAAF RALP
Subjt:  GHAALSKLVKNANKYPVAAFTRALP

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LP76 dCTP pyrophosphatase 1

1.1e-63

100

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Query:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFTRALP
        GHAALSKLVKNANKYPVAAFTRALP
Subjt:  GHAALSKLVKNANKYPVAAFTRALP

A0A1S3BWI5 dCTP pyrophosphatase 1

1.2e-62

98.4

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Query:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFTRALP
        GHAA+SKLVKNANKYPVAA TRALP
Subjt:  GHAALSKLVKNANKYPVAAFTRALP

A0A5A7UWT3 dCTP pyrophosphatase 1

1.2e-62

98.4

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Query:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFTRALP
        GHAA+SKLVKNANKYPVAA TRALP
Subjt:  GHAALSKLVKNANKYPVAAFTRALP

A0A6J1E6P9 dCTP pyrophosphatase 1

2.0e-62

98.4

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Query:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEKTAKDVSLQELRD LAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFTRALP
        GHAALSKLVKNANKYPVAAF RALP
Subjt:  GHAALSKLVKNANKYPVAAFTRALP

A0A6J1JJF8 dCTP pyrophosphatase 1

7.6e-62

97.6

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Query:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEKTAKDVSLQELRD L EFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFTRALP
        GHAALSKLVKNANKYPVAAF RALP
Subjt:  GHAALSKLVKNANKYPVAAFTRALP

SwissProt top hits

e value

%identity

Alignment

Q32KY6 dCTP pyrophosphatase 1

2.9e-26

53.64

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Query:  PEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAALSK
        P   + + +L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   WS  ER  L+EE+SD+L+YLV LA  C +DL  A L K
Subjt:  PEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAALSK

Query:  LVKNANKYPV
        +  N  +YPV
Subjt:  LVKNANKYPV

Q91VC0 dCTP pyrophosphatase 1

5.9e-27

54.87

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Query:  SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAA
        S+ PE T     L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   W   ER  L+EE+SDVL+YLV LA  C +DL  A 
Subjt:  SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAA

Query:  LSKLVKNANKYPV
        +SK+  N  +YPV
Subjt:  LSKLVKNANKYPV

Q9H773 dCTP pyrophosphatase 1

2.9e-26

56.25

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Query:  SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAA
        S+ PE T     L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   WS  ER  L+EE+SDVL+YLV LA  C +DL  A 
Subjt:  SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAA

Query:  LSKLVKNANKYP
        LSK+  N  +YP
Subjt:  LSKLVKNANKYP

Q9QY93 dCTP pyrophosphatase 1

1.3e-26

50.86

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Query:  ENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLG
        ++ +  P + + + +L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   W   ER  L+EE+SDVL+YLV LA  C +DL 
Subjt:  ENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLG

Query:  HAALSKLVKNANKYPV
         A +SK+  N  +YPV
Subjt:  HAALSKLVKNANKYPV

Arabidopsis top hits

e value

%identity

Alignment

AT3G25400.1 CONTAINS InterPro DOMAIN/s: NTP Pyrophosphohydrolase MazG-related, RS21-C6 (InterPro:IPR011394), EAR (InterPro:IPR009039), NTP pyrophosphohydrolase MazG, putative catalytic core (InterPro:IPR004518); Has 1123 Blast hits to 1121 proteins in 452 species: Archae - 22; Bacteria - 753; Metazoa - 81; Fungi - 3; Plants - 83; Viruses - 0; Other Eukaryotes - 181 (source: NCBI BLink).

2.2e-37

64.35

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Query:  NRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGH
        N+  E  +  + VSLQ L  ++ +FA+ R WE+YHSPRNLLLA+VGEVGELSEIFQWKGEV RG P+W   E+ HL EE+SDVLLYLVRL+D CG+DLG 
Subjt:  NRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGH

Query:  AALSKLVKNANKYPV
        AAL K+  NA KYPV
Subjt:  AALSKLVKNANKYPV

Sequences

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CDS sequence

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ATGGAGAATCGTTCTTACGAACCTGAAAAAACCGCCAAAGACGTCTCGCTGCAAGAACTCAGAGACAGACTCGCAGAGTTCGCTCGAGTCCGAGGATGGGAGCAGTACCA
CAGCCCTAGAAACCTGCTCCTAGCACTTGTTGGTGAAGTCGGAGAGCTATCGGAGATATTCCAGTGGAAAGGAGAAGTGGAGAGGGGGCTACCGAACTGGAGCGCGGCGG
AGAGAGAGCATTTGGAAGAAGAAGTATCGGATGTATTGCTCTATTTGGTGCGTCTCGCCGATGTATGTGGCCTTGATCTCGGCCATGCCGCTCTCTCGAAGCTCGTCAAA
AATGCCAACAAGTATCCTGTCGCCGCTTTCACTCGCGCTCTGCCATGA

mRNA sequence

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TCGGGTTTTTCCTTTCCGAAGTAGGTTAATTTTGAATAAAGAGTACCGCTACAAAAAGGCATATTTAGCCTGACTAAAAGTATTCCTAAATATATCCTCTAAACTTGCGA
AAATGATCATAAGTCAACTAACCACTTGTACAATCGACCTTAGAGGTCTGAGGTTCGATTCTCTCATACTACATTGTTACATTACATACGTATAGTTTAAAGTTAACCCA
ACTAATACAGAACATTCACATAATTGAACTGGGATCGAAGATCCAAAAGTCACACAAACTTCAAGTTCAAAAGATTGAAAGAAGATGGGATGTAATTTGTGGTGTAGAAA
AGTGGTGAGAGACATGGCATGGCATGAGGTGCAGCAGCAAATAGGTGATTTGAACTTTGAAGTGATGAATGGAAAGATGGAGACAAGCTTTCCCACACTTCACATGCCTT
AATTACTATTTTATCTTTTTATCAAACACCTCAAGTGCACGTCCCACTATCATCATCAAATTCCCTCTGTCTCTATCTCATTCTCTCTCTCCCTAAACTAACTTCTATAA
ATTAAAACCCCAACCGAACTCAGAGATCACAACCACAAGCAGATAAAAACAGATCACAGAGAGAGACATGGAGAATCGTTCTTACGAACCTGAAAAAACCGCCAAAGACG
TCTCGCTGCAAGAACTCAGAGACAGACTCGCAGAGTTCGCTCGAGTCCGAGGATGGGAGCAGTACCACAGCCCTAGAAACCTGCTCCTAGCACTTGTTGGTGAAGTCGGA
GAGCTATCGGAGATATTCCAGTGGAAAGGAGAAGTGGAGAGGGGGCTACCGAACTGGAGCGCGGCGGAGAGAGAGCATTTGGAAGAAGAAGTATCGGATGTATTGCTCTA
TTTGGTGCGTCTCGCCGATGTATGTGGCCTTGATCTCGGCCATGCCGCTCTCTCGAAGCTCGTCAAAAATGCCAACAAGTATCCTGTCGCCGCTTTCACTCGCGCTCTGC
CATGAACTTCGCGCCCTTCTCTTTTTCGTTTTTCTCTCTAATTTTTATGTTTTGTTAGGACAATGATTGAATGCACTCAATCCACCACTCAAGTTTTTTCCTTTTTGTAT
TTGTTTTTCTTGGTTTACTAATACTCATAAAGATTTCCTAATGCTCTCGTTTCTATATTTTTATCTATAAACAAATCATCGATTAAAATA

Protein sequence

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MENRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAALSKLVK
NANKYPVAAFTRALP

PI0005136 (gene) of Melon (PI 482460) v1 genome