CuGenDBv2

Gene ID	PI0012770
Organism	Cucumis metuliferus PI 482460 (Melon (PI 482460) v1)
Description	Reverse transcriptase
Genome location	chr01:19913258..19913719
RNA-Seq Expression	PI0012770
Synteny	PI0012770
Gene Ontology terms	GO:1901800 - positive regulation of proteasomal protein catabolic process (biological process) GO:0090305 - nucleic acid phosphodiester bond hydrolysis (biological process) GO:0006278 - RNA-dependent DNA biosynthetic process (biological process) GO:0015074 - DNA integration (biological process) GO:0005634 - nucleus (cellular component) GO:0005737 - cytoplasm (cellular component) GO:0000502 - proteasome complex (cellular component) GO:0008194 - UDP-glycosyltransferase activity (molecular function) GO:0036402 - proteasome-activating ATPase activity (molecular function) GO:0016887 - ATPase activity (molecular function) GO:0008270 - zinc ion binding (molecular function) GO:0005524 - ATP binding (molecular function) GO:0004519 - endonuclease activity (molecular function) GO:0004190 - aspartic-type endopeptidase activity (molecular function) GO:0003964 - RNA-directed DNA polymerase activity (molecular function) GO:0003676 - nucleic acid binding (molecular function)
InterPro domains	IPR043502 - DNA/RNA polymerase superfamily IPR043128 - Reverse transcriptase/Diguanylate cyclase domain IPR000477 - Reverse transcriptase domain

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAA0025848.1 pol protein [Cucumis melo var. makuwa]

1.6e-71

87.58

Show/hide

Query:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW
        MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDIL+YSKTEAEHE+HLH+VLETL+ N+L+AKFSKCEFWLR+V+FLGHVVS +GVSVDPAKIEAVTNW
Subjt:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW

Query:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF
        + PS+VSE+RSFLGLA YYRRFVEDFSRIASPLTQLTRKGTPFVWS AC+ SF
Subjt:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF

KAA0031437.1 pol protein [Cucumis melo var. makuwa]

1.6e-71

87.58

Show/hide

Query:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW
        MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDIL+YSKTEAEHE+HLH+VLETL+ N+L+AKFSKCEFWLR+V+FLGHVVS +GVSVDPAKIEAVTNW
Subjt:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW

Query:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF
        + PS+VSE+RSFLGLA YYRRFVEDFSRIASPLTQLTRKGTPFVWS AC+ SF
Subjt:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF

KAA0033825.1 pol protein [Cucumis melo var. makuwa]

1.6e-71

87.58

Show/hide

Query:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW
        MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDIL+YSKTEAEHE+HLH+VLETL+ N+L+AKFSKCEFWLR+V+FLGHVVS +GVSVDPAKIEAVTNW
Subjt:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW

Query:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF
        + PS+VSE+RSFLGLA YYRRFVEDFSRIASPLTQLTRKGTPFVWS AC+ SF
Subjt:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF

TYK28368.1 pol protein [Cucumis melo var. makuwa]

1.6e-71

87.58

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Query:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW
        MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDIL+YSKTEAEHE+HLH+VLETL+ N+L+AKFSKCEFWLR+V+FLGHVVS +GVSVDPAKIEAVTNW
Subjt:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW

Query:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF
        + PS+VSE+RSFLGLA YYRRFVEDFSRIASPLTQLTRKGTPFVWS AC+ SF
Subjt:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF

TYK28422.1 pol protein [Cucumis melo var. makuwa]

1.6e-71

87.58

Show/hide

Query:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW
        MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDIL+YSKTEAEHE+HLH+VLETL+ N+L+AKFSKCEFWLR+V+FLGHVVS +GVSVDPAKIEAVTNW
Subjt:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW

Query:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF
        + PS+VSE+RSFLGLA YYRRFVEDFSRIASPLTQLTRKGTPFVWS AC+ SF
Subjt:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF

TrEMBL top hits

e value

%identity

Alignment

A0A5A7TEQ2 Reverse transcriptase

7.6e-72

87.58

Show/hide

Query:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW
        MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDIL+YSKTEAEHE+HLH+VLETL+ N+L+AKFSKCEFWLR+V+FLGHVVS +GVSVDPAKIEAVTNW
Subjt:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW

Query:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF
        + PS+VSE+RSFLGLA YYRRFVEDFSRIASPLTQLTRKGTPFVWS AC+ SF
Subjt:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF

A0A5A7TSL0 Reverse transcriptase

7.6e-72

87.58

Show/hide

Query:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW
        MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDIL+YSKTEAEHE+HLH+VLETL+ N+L+AKFSKCEFWLR+V+FLGHVVS +GVSVDPAKIEAVTNW
Subjt:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW

Query:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF
        + PS+VSE+RSFLGLA YYRRFVEDFSRIASPLTQLTRKGTPFVWS AC+ SF
Subjt:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF

A0A5A7UBS1 Reverse transcriptase

7.6e-72

87.58

Show/hide

Query:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW
        MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDIL+YSKTEAEHE+HLH+VLETL+ N+L+AKFSKCEFWLR+V+FLGHVVS +GVSVDPAKIEAVTNW
Subjt:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW

Query:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF
        + PS+VSE+RSFLGLA YYRRFVEDFSRIASPLTQLTRKGTPFVWS AC+ SF
Subjt:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF

A0A5D3CQB5 Reverse transcriptase

7.6e-72

87.58

Show/hide

Query:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW
        MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDIL+YSKTEAEHE+HLH+VLETL+ N+L+AKFSKCEFWLR+V+FLGHVVS +GVSVDPAKIEAVTNW
Subjt:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW

Query:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF
        + PS+VSE+RSFLGLA YYRRFVEDFSRIASPLTQLTRKGTPFVWS AC+ SF
Subjt:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF

A0A5D3DY07 Reverse transcriptase

7.6e-72

87.58

Show/hide

Query:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW
        MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDIL+YSKTEAEHE+HLH+VLETL+ N+L+AKFSKCEFWLR+V+FLGHVVS +GVSVDPAKIEAVTNW
Subjt:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW

Query:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF
        + PS+VSE+RSFLGLA YYRRFVEDFSRIASPLTQLTRKGTPFVWS AC+ SF
Subjt:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF

SwissProt top hits

e value

%identity

Alignment

P04323 Retrovirus-related Pol polyprotein from transposon 17.6

3.2e-27

41.01

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Query:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW
        M FGL NAPA F   MN + +  L+   +V++DDI+V+S +  EH   L  V E L    L  +  KCEF  ++ +FLGHV++ DG+  +P KIEA+  +
Subjt:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW

Query:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRK
         +P+   E+++FLGL  YYR+F+ +F+ IA P+T+  +K
Subjt:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRK

P0CT41 Transposon Tf2-12 polyprotein

6.3e-23

35.62

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Query:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW
        M +G++ APA F   +N +  E  +S V+ ++DDIL++SK+E+EH  H+  VL+ L+   L    +KCEF   QV F+G+ +S+ G +     I+ V  W
Subjt:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW

Query:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWS
          P +  E+R FLG  +Y R+F+   S++  PL  L +K   + W+
Subjt:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWS

P10401 Retrovirus-related Pol polyprotein from transposon gypsy

1.5e-24

38.41

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Query:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW
        + FGL NA ++F   ++ V +E +     V++DD++++S+ E++H  H+  VL+ L    +     K  F+   V +LG +VSKDG   DP K++A+  +
Subjt:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW

Query:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTR
          P  V +VRSFLGLASYYR F++DF+ IA P+T + +
Subjt:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTR

P20825 Retrovirus-related Pol polyprotein from transposon 297

5.5e-27

37.59

Show/hide

Query:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW
        M FGL NAPA F   MN + +  L+   +V++DDI+++S +  EH + +  V   L    L  +  KCEF  ++ +FLGH+V+ DG+  +P K++A+ ++
Subjt:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW

Query:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGT
         +P+   E+R+FLGL  YYR+F+ +++ IA P+T   +K T
Subjt:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGT

Q8I7P9 Retrovirus-related Pol polyprotein from transposon opus

9.4e-27

40.58

Show/hide

Query:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW
        + FGL NAPA+F  +++ + +E +     V+IDDI+V+S+    H  +L  VL +L    L     K  F   QV FLG++V+ DG+  DP K+ A++  
Subjt:  MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNW

Query:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTR
          P+SV E++ FLG+ SYYR+F++D++++A PLT LTR
Subjt:  SVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTR

Arabidopsis top hits

e value

%identity

Alignment

ATMG00860.1 DNA/RNA polymerases superfamily protein

2.3e-20

44.33

Show/hide

Query:  DHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLG--HVVSKDGVSVDPAKIEAVTNWSVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGT
        +HL  VL+  + +Q +A   KC F   Q+++LG  H++S +GVS DPAK+EA+  W  P + +E+R FLGL  YYRRFV+++ +I  PLT+L +K +
Subjt:  DHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLG--HVVSKDGVSVDPAKIEAVTNWSVPSSVSEVRSFLGLASYYRRFVEDFSRIASPLTQLTRKGT

Sequences

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CDS sequence

Show/hide CDS sequence

ATGTCTTTTGGTTTGACTAACGCTCCTGCTGTATTCATGGATCTGATGAACAGGGTGTTCAAGGAATTCCTGGACTCATTTGTGATTGTGTTCATTGATGACATCTTAGT
CTACTCCAAGACGGAGGCCGAACATGAGGATCATTTGCATAAGGTCTTGGAGACACTTCAAGTGAACCAGTTGTTTGCTAAGTTCTCGAAGTGCGAGTTTTGGTTGAGGC
AGGTATCCTTCCTAGGCCATGTGGTGTCCAAGGACGGTGTTTCAGTGGATCCAGCTAAGATTGAAGCGGTCACCAACTGGTCTGTACCTTCCTCAGTTAGCGAGGTTCGT
AGTTTTCTGGGTCTTGCAAGTTATTATCGTAGGTTTGTGGAGGATTTCTCCCGCATTGCTTCTCCGTTGACCCAGTTGACTAGAAAAGGGACTCCATTTGTGTGGAGTAA
GGCTTGTGATGACAGTTTCTAG

mRNA sequence

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Protein sequence

Show/hide protein sequence

MSFGLTNAPAVFMDLMNRVFKEFLDSFVIVFIDDILVYSKTEAEHEDHLHKVLETLQVNQLFAKFSKCEFWLRQVSFLGHVVSKDGVSVDPAKIEAVTNWSVPSSVSEVR
SFLGLASYYRRFVEDFSRIASPLTQLTRKGTPFVWSKACDDSF

PI0012770 (gene) of Melon (PI 482460) v1 genome