CuGenDBv2

Gene ID	PI0019328
Organism	Cucumis metuliferus PI 482460 (Melon (PI 482460) v1)
Description	DNA topoisomerase
Genome location	chr04:30786067..30804673
RNA-Seq Expression	PI0019328
Synteny	PI0019328
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0005694 - chromosome (cellular component) GO:0003677 - DNA binding (molecular function) GO:0046872 - metal ion binding (molecular function) GO:0003917 - DNA topoisomerase type I activity (molecular function) GO:0003729 - mRNA binding (molecular function)
InterPro domains	IPR006171 - TOPRIM domain IPR028612 - DNA topoisomerase I, type IA IPR025589 - Topoisomerase C-terminal repeat IPR023406 - DNA topoisomerase, type IA, active site IPR023405 - DNA topoisomerase, type IA, core domain IPR013826 - DNA topoisomerase, type IA, central region, subdomain 3 IPR013825 - DNA topoisomerase, type IA, central region, subdomain 2 IPR013824 - DNA topoisomerase, type IA, central region, subdomain 1 IPR013498 - DNA topoisomerase, type IA, zn finger IPR013497 - DNA topoisomerase, type IA, central IPR005733 - DNA topoisomerase I, bacterial-type IPR003602 - DNA topoisomerase, type IA, DNA-binding domain IPR003601 - DNA topoisomerase, type IA, domain 2 IPR000380 - DNA topoisomerase, type IA

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0038738.1 DNA topoisomerase 1 isoform X1 [Cucumis melo var. makuwa]

0.0e+00

78.82

Show/hide

Query:  LVSSNSSSSIRKASKGLKEKKSRSKKKKEAISSTNDA-------DTKKANLVSSNS-------------SSSIRKASKGLNVKKSRSKKKKEAISSTNDA
        LVSSNSSSSIR+ASKGL EKKS SKKKK+AISSTNDA       D++  +  SSN+             SS+IRKASKGLN KKS SK KKEAISSTNDA
Subjt:  LVSSNSSSSIRKASKGLKEKKSRSKKKKEAISSTNDA-------DTKKANLVSSNS-------------SSSIRKASKGLNVKKSRSKKKKEAISSTNDA

Query:  DVEEVCK--------------DVIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVV
        DVE VCK              DV+QDPKKN T+GTSKDS STK+QSNKKK NSSRNKEATK ANKL QKPNV+VD RGTSQG+TTFKQLYPPMGKSV+VV
Subjt:  DVEEVCK--------------DVIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVV

Query:  ESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGI
        ESV KAKVIQ+YLGDMFVVLPSHGHVRDLAARSGSVRP+DDFIMVWEVPSAAWTHLKSIE+SLNGAENLILASDPDQEGEAIAWHIIEMLQHQ+ALHEGI
Subjt:  ESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGI

Query:  SIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPC
        SIARVVFHEITEASIK+ALQSPRVID N+VQAYLARRALDYLIGFNISPLLW+KLPGC+SPGRVQSAALALICDRE EID+F AQEYWTID++LNQKDPC
Subjt:  SIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPC

Query:  SSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAA
        SSVEDFAVPA LTHFDSKKLN F ISSN EAKNIETALKSVNFQVL S KN V T+PPMPYITSTLQQDAA KFNFPATYTMKLAQKLYEGIQLADG AA
Subjt:  SSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAA

Query:  GLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQ
        GLITYPRTDG HISDEAVKD+ SLIM+R+GQ+FV +SG +YFKKV NAQEA EAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRT+ACQME SITE+I+
Subjt:  GLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQ

Query:  IDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTF
        IDCGLAD+SII+ STCSRVQFRGF+ VFEDPEVHAVKHKDHEESGRDELFRILN LKPGD+LSLLAVEL++HFTQPPPRY+EGTLVKRMEELGIGRPST+
Subjt:  IDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTF

Query:  ATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDY
        AT LKVL+DRNYV+VKS +LHPEFRG IVSAFLCHHFS +T    TA++E KLDNVSAG T+WKRLLRD W Q+SS CKRANNV I+QVEKMLE+KY D+
Subjt:  ATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDY

Query:  LFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSA-EEPKVIGVHPVLNEK--------------------
        LFS LP+NSR CPSCPDGTLS KV   G+GYYIGCD+ P CK+VAKT +GE EDK P   +    +EPKVIGVHPV NEK                    
Subjt:  LFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSA-EEPKVIGVHPVLNEK--------------------

Query:  ------IILKNGPFGFYVQLGEDRKGYVPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLA
              I+LKNGPFGFYVQLGEDRKGYVPKRAS+ EIKD NSITL+VA+DRLRYPI LG HPKDG+PVI+KIARVGFT+RH RTIAS+PK++KP  + LA
Subjt:  ------IILKNGPFGFYVQLGEDRKGYVPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLA

Query:  KALKLLSSSAVRRVGRPKSP
        KALKLLSSS VRR+GRPK P
Subjt:  KALKLLSSSAVRRVGRPKSP

XP_011652538.2 uncharacterized protein LOC101210823 isoform X2 [Cucumis sativus]

0.0e+00

80.61

Show/hide

Query:  YLVSSNSSSSIRKASKGLKEKKSRSKKKKEAISS-----------TNDAD-----TKKANLVSSNSSSSIRKASKGLNVKKSRSKKKKEAISSTNDADVE
        Y     S+  I  ++K LK +K  +  +K+ IS+           TN +D      K+ANLVS  SSSS RKASKGLN KKSRSKKKKEAISSTNDADV+
Subjt:  YLVSSNSSSSIRKASKGLKEKKSRSKKKKEAISS-----------TNDAD-----TKKANLVSSNSSSSIRKASKGLNVKKSRSKKKKEAISSTNDADVE

Query:  EVCK--------------DVIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVVESV
         VCK              DV+QDPKKN T GTSKDSASTK++SNK+K +SSR KEATK ANKL QKP+VVVDARGTSQ RTTFKQLYPPMGKSV++VESV
Subjt:  EVCK--------------DVIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVVESV

Query:  VKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGISIA
         KAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIE+SLNGAENLILASDPDQEGEAIAWHIIEMLQHQN+LHEGISIA
Subjt:  VKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGISIA

Query:  RVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPCSSV
        RVVFHEITEASIK+ALQSPRVID N+VQAYLARRALDYLIGFNISPLLW+KLPGC+SPGRVQSAALALICDRE EIDEFHAQEYWTIDI+LNQK+PCSSV
Subjt:  RVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPCSSV

Query:  EDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAAGLI
         DFAVPA LTHFD KKLN  AISSN EAKNIETALKSVNFQVL S+K+ V T+PPMPYITSTLQQDAANKFNFPA+YTM+LAQKLYEGIQLADG AAGLI
Subjt:  EDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAAGLI

Query:  TYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQIDC
        TYPRTDG HISDEAVKD+ SLIM+RYGQ+FV +SG +YFKKVN AQEA EAIRPTDVQ LPSMLVG LDEDSHKLYSLIWLRT+ACQME SI+EQI+IDC
Subjt:  TYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQIDC

Query:  GLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTFATT
        GL D+SI+SGSTCSRVQFRGFQ++FEDPEVHAVKH++HEESG+DELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPST+ATT
Subjt:  GLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTFATT

Query:  LKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDYLFS
        +KVLQDRNYVSVKS VLHPEFRG IVSAFLCHHFSEV+ C  TA++E KLDNVSAG T+WK  LRD WTQ+SS CKRANNV ++QVEKMLE+KY D+LFS
Subjt:  LKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDYLFS

Query:  LLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSE--SSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKGYV
         LPDNSR CPSCPDGTL  KV RFGVGYYIGCDQHP CK+VAKTL+GE EDK   PSE  +   EPKV+G+HPVL EK++LK GPFG Y+QLGEDRKGY+
Subjt:  LLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSE--SSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKGYV

Query:  PKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRPK
        PKRASVFEIKDVNSITL+ A+DRLRYPI LG HPKDG+PVIIKIAR GFTIRH RTIASIPKNLKPN++DLAKALKLLSSS VRRVGRPK
Subjt:  PKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRPK

XP_016903545.1 PREDICTED: DNA topoisomerase 1 isoform X1 [Cucumis melo]

0.0e+00

80.89

Show/hide

Query:  LVSSNSSSSIRKASKGLKEKKSRSKKKKEAISSTNDA-------DTKKANLVSSNS-------------SSSIRKASKGLNVKKSRSKKKKEAISSTNDA
        LVSSNSSSSIR+ASKGL EKKS SKKKK+AISSTNDA       D++  +  SSN+             SS+IRKASKGLN KKS SK KKEAISSTNDA
Subjt:  LVSSNSSSSIRKASKGLKEKKSRSKKKKEAISSTNDA-------DTKKANLVSSNS-------------SSSIRKASKGLNVKKSRSKKKKEAISSTNDA

Query:  DVEEVCK--------------DVIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVV
        DVE VCK              DV+QDPKKN T+GTSKDS STK+QSNKKK NSSRNKEATK ANKL QKPNV+VD RGTSQG+TTFKQLYPPMGKSV+VV
Subjt:  DVEEVCK--------------DVIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVV

Query:  ESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGI
        ESV KAKVIQ+YLGDMFVVLPSHGHVRDLAARSGSVRP+DDFIMVWEVPSAAWTHLKSIE+SLNGAENLILASDPDQEGEAIAWHIIEMLQHQ+ALHEGI
Subjt:  ESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGI

Query:  SIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPC
        SIARVVFHEITEASIK+ALQSPRVID N+VQAYLARRALDYLIGFNISPLLW+KLPGC+SPGRVQSAALALICDRE EID+F AQEYWTID++LNQKDPC
Subjt:  SIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPC

Query:  SSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAA
        SSVEDFAVPA LTHFDSKKLN F ISSN EAKNIETALKSVNFQVL S KN V T+PPMPYITSTLQQDAA KFNFPATYTMKLAQKLYEGIQLADG AA
Subjt:  SSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAA

Query:  GLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQ
        GLITYPRTDG HISDEAVKD+ SLIM+R+GQ+FV +SG +YFKKV NAQEA EAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRT+ACQME SITE+I+
Subjt:  GLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQ

Query:  IDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTF
        IDCGLAD+SII+ STCSRVQFRGF+ VFEDPEVHAVKHKDHEESGRDELFRILN LKPGD+LSLLAVEL++HFTQPPPRY+EGTLVKRMEELGIGRPST+
Subjt:  IDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTF

Query:  ATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDY
        AT LKVL+DRNYV+VKS +LHPEFRG IVSAFLCHHFS +T    TA++E KLDNVSAG T+WKRLLRD W Q+SS CKRANNV I+QVEKMLE+KY D+
Subjt:  ATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDY

Query:  LFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSA-EEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKG
        LFS LP+NSR CPSCPDGTLS KV   G+GYYIGCD+ P CK+VAKT +GE EDK P   +    +EPKVIGVHPV NEKI+LKNGPFGFYVQLGEDRKG
Subjt:  LFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSA-EEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKG

Query:  YVPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRPKSP
        YVPKRAS+ EIKD NSITL+VA+DRLRYPI LG HPKDG+PVI+KIARVGFT+RH RTIAS+PK++KP  + LAKALKLLSSS VRR+GRPK P
Subjt:  YVPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRPKSP

XP_016903546.1 PREDICTED: DNA topoisomerase 1 isoform X2 [Cucumis melo]

0.0e+00

80.54

Show/hide

Query:  LVSSNSSSSIRKASKGLKEKKSRSKKKKEAISSTNDA-------DTKKANLVSSNS-------------SSSIRKASKGLNVKKSRSKKKKEAISSTNDA
        LVSSNSSSSIR+ASKGL EKKS SKKKK+AISSTNDA       D++  +  SSN+             SS+IRKASKGLN KKS SK KKEAISSTNDA
Subjt:  LVSSNSSSSIRKASKGLKEKKSRSKKKKEAISSTNDA-------DTKKANLVSSNS-------------SSSIRKASKGLNVKKSRSKKKKEAISSTNDA

Query:  DVEEVCK--------------DVIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVV
        DVE VCK              DV+QDPKKN T+GTSKDS STK+QSNKKK NSSRNKEATK ANKL QKPNV+VD RGTSQG+TTFKQLYPPMGKSV+VV
Subjt:  DVEEVCK--------------DVIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVV

Query:  ESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGI
        ESV KAKVIQ+YLGDMFVVLPSHGHVRDLAARSGSVRP+DDFIMVWEVPSAAWTHLKSIE+SLNGAENLILASDPDQEGEAIAWHIIEMLQHQ+ALHEGI
Subjt:  ESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGI

Query:  SIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPC
        SIARVVFHEITEASIK+ALQSPRVID N+VQAYLARRALDYLIGFNISPLLW+KLPGC+SPGRVQSAALALICDRE EID+F AQEYWTID++LNQKDPC
Subjt:  SIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPC

Query:  SSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAA
        SSVEDFAVPA LTHFDSKKLN F ISSN EAKNIETALKSVNFQVL S KN V T+PPMPYITSTLQQDAA KFNFPATYTMKLAQKLYEGIQLADG AA
Subjt:  SSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAA

Query:  GLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQ
        GLITYPRTDG HISDEAVKD+ SLIM+R+GQ+FV +SG +YFKKV NAQEA EAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRT+ACQME SITE+I+
Subjt:  GLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQ

Query:  IDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTF
        IDCGLAD+SII+ STCSRVQFRGF+ VFEDPEVHAVKHKDHEESGRDELFRILN LKPGDQLSL AVELKQHFTQPPPRYSEGTLVK+MEELGIGRPST+
Subjt:  IDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTF

Query:  ATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDY
        ATTLKVL+DR YVSVKSRVLHPEFRG +VSAFL HHFSEVT   FTA+ME +LDNVSAG T+WK LLRD+WT+ SS  +R N+V IHQVEKMLE+KY D+
Subjt:  ATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDY

Query:  LFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKGY
        LFS LPDNSR CPSC +GTL  K+ RFG GY+IGCDQHPRCKH+AKTL+GE ED     +++S +EPK++G+HP LNEKI+LK GPFGFYVQLGEDRKG+
Subjt:  LFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKGY

Query:  VPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRPKS
        +PKRAS+ +IKDV+SITLE AV+RL YP+ LG HPKDG PVIIK+ARVGF + HRRT ASIP+NLKPNDIDLAKAL+LLSSS++RR GR KS
Subjt:  VPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRPKS

XP_031737509.1 uncharacterized protein LOC101210823 isoform X1 [Cucumis sativus]

0.0e+00

80.61

Show/hide

Query:  YLVSSNSSSSIRKASKGLKEKKSRSKKKKEAISS-----------TNDAD-----TKKANLVSSNSSSSIRKASKGLNVKKSRSKKKKEAISSTNDADVE
        Y     S+  I  ++K LK +K  +  +K+ IS+           TN +D      K+ANLVS  SSSS RKASKGLN KKSRSKKKKEAISSTNDADV+
Subjt:  YLVSSNSSSSIRKASKGLKEKKSRSKKKKEAISS-----------TNDAD-----TKKANLVSSNSSSSIRKASKGLNVKKSRSKKKKEAISSTNDADVE

Query:  EVCK--------------DVIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVVESV
         VCK              DV+QDPKKN T GTSKDSASTK++SNK+K +SSR KEATK ANKL QKP+VVVDARGTSQ RTTFKQLYPPMGKSV++VESV
Subjt:  EVCK--------------DVIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVVESV

Query:  VKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGISIA
         KAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIE+SLNGAENLILASDPDQEGEAIAWHIIEMLQHQN+LHEGISIA
Subjt:  VKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGISIA

Query:  RVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPCSSV
        RVVFHEITEASIK+ALQSPRVID N+VQAYLARRALDYLIGFNISPLLW+KLPGC+SPGRVQSAALALICDRE EIDEFHAQEYWTIDI+LNQK+PCSSV
Subjt:  RVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPCSSV

Query:  EDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAAGLI
         DFAVPA LTHFD KKLN  AISSN EAKNIETALKSVNFQVL S+K+ V T+PPMPYITSTLQQDAANKFNFPA+YTM+LAQKLYEGIQLADG AAGLI
Subjt:  EDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAAGLI

Query:  TYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQIDC
        TYPRTDG HISDEAVKD+ SLIM+RYGQ+FV +SG +YFKKVN AQEA EAIRPTDVQ LPSMLVG LDEDSHKLYSLIWLRT+ACQME SI+EQI+IDC
Subjt:  TYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQIDC

Query:  GLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTFATT
        GL D+SI+SGSTCSRVQFRGFQ++FEDPEVHAVKH++HEESG+DELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPST+ATT
Subjt:  GLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTFATT

Query:  LKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDYLFS
        +KVLQDRNYVSVKS VLHPEFRG IVSAFLCHHFSEV+ C  TA++E KLDNVSAG T+WK  LRD WTQ+SS CKRANNV ++QVEKMLE+KY D+LFS
Subjt:  LKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDYLFS

Query:  LLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSE--SSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKGYV
         LPDNSR CPSCPDGTL  KV RFGVGYYIGCDQHP CK+VAKTL+GE EDK   PSE  +   EPKV+G+HPVL EK++LK GPFG Y+QLGEDRKGY+
Subjt:  LLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSE--SSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKGYV

Query:  PKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRPK
        PKRASVFEIKDVNSITL+ A+DRLRYPI LG HPKDG+PVIIKIAR GFTIRH RTIASIPKNLKPN++DLAKALKLLSSS VRRVGRPK
Subjt:  PKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRPK

TrEMBL top hits

e value

%identity

Alignment

A0A1S4E5M8 Omega-protein

0.0e+00

80.54

Show/hide

Query:  LVSSNSSSSIRKASKGLKEKKSRSKKKKEAISSTNDA-------DTKKANLVSSNS-------------SSSIRKASKGLNVKKSRSKKKKEAISSTNDA
        LVSSNSSSSIR+ASKGL EKKS SKKKK+AISSTNDA       D++  +  SSN+             SS+IRKASKGLN KKS SK KKEAISSTNDA
Subjt:  LVSSNSSSSIRKASKGLKEKKSRSKKKKEAISSTNDA-------DTKKANLVSSNS-------------SSSIRKASKGLNVKKSRSKKKKEAISSTNDA

Query:  DVEEVCK--------------DVIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVV
        DVE VCK              DV+QDPKKN T+GTSKDS STK+QSNKKK NSSRNKEATK ANKL QKPNV+VD RGTSQG+TTFKQLYPPMGKSV+VV
Subjt:  DVEEVCK--------------DVIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVV

Query:  ESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGI
        ESV KAKVIQ+YLGDMFVVLPSHGHVRDLAARSGSVRP+DDFIMVWEVPSAAWTHLKSIE+SLNGAENLILASDPDQEGEAIAWHIIEMLQHQ+ALHEGI
Subjt:  ESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGI

Query:  SIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPC
        SIARVVFHEITEASIK+ALQSPRVID N+VQAYLARRALDYLIGFNISPLLW+KLPGC+SPGRVQSAALALICDRE EID+F AQEYWTID++LNQKDPC
Subjt:  SIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPC

Query:  SSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAA
        SSVEDFAVPA LTHFDSKKLN F ISSN EAKNIETALKSVNFQVL S KN V T+PPMPYITSTLQQDAA KFNFPATYTMKLAQKLYEGIQLADG AA
Subjt:  SSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAA

Query:  GLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQ
        GLITYPRTDG HISDEAVKD+ SLIM+R+GQ+FV +SG +YFKKV NAQEA EAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRT+ACQME SITE+I+
Subjt:  GLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQ

Query:  IDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTF
        IDCGLAD+SII+ STCSRVQFRGF+ VFEDPEVHAVKHKDHEESGRDELFRILN LKPGDQLSL AVELKQHFTQPPPRYSEGTLVK+MEELGIGRPST+
Subjt:  IDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTF

Query:  ATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDY
        ATTLKVL+DR YVSVKSRVLHPEFRG +VSAFL HHFSEVT   FTA+ME +LDNVSAG T+WK LLRD+WT+ SS  +R N+V IHQVEKMLE+KY D+
Subjt:  ATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDY

Query:  LFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKGY
        LFS LPDNSR CPSC +GTL  K+ RFG GY+IGCDQHPRCKH+AKTL+GE ED     +++S +EPK++G+HP LNEKI+LK GPFGFYVQLGEDRKG+
Subjt:  LFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKGY

Query:  VPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRPKS
        +PKRAS+ +IKDV+SITLE AV+RL YP+ LG HPKDG PVIIK+ARVGF + HRRT ASIP+NLKPNDIDLAKAL+LLSSS++RR GR KS
Subjt:  VPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRPKS

A0A1S4E6F1 DNA topoisomerase

0.0e+00

80.89

Show/hide

Query:  LVSSNSSSSIRKASKGLKEKKSRSKKKKEAISSTNDA-------DTKKANLVSSNS-------------SSSIRKASKGLNVKKSRSKKKKEAISSTNDA
        LVSSNSSSSIR+ASKGL EKKS SKKKK+AISSTNDA       D++  +  SSN+             SS+IRKASKGLN KKS SK KKEAISSTNDA
Subjt:  LVSSNSSSSIRKASKGLKEKKSRSKKKKEAISSTNDA-------DTKKANLVSSNS-------------SSSIRKASKGLNVKKSRSKKKKEAISSTNDA

Query:  DVEEVCK--------------DVIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVV
        DVE VCK              DV+QDPKKN T+GTSKDS STK+QSNKKK NSSRNKEATK ANKL QKPNV+VD RGTSQG+TTFKQLYPPMGKSV+VV
Subjt:  DVEEVCK--------------DVIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVV

Query:  ESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGI
        ESV KAKVIQ+YLGDMFVVLPSHGHVRDLAARSGSVRP+DDFIMVWEVPSAAWTHLKSIE+SLNGAENLILASDPDQEGEAIAWHIIEMLQHQ+ALHEGI
Subjt:  ESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGI

Query:  SIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPC
        SIARVVFHEITEASIK+ALQSPRVID N+VQAYLARRALDYLIGFNISPLLW+KLPGC+SPGRVQSAALALICDRE EID+F AQEYWTID++LNQKDPC
Subjt:  SIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPC

Query:  SSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAA
        SSVEDFAVPA LTHFDSKKLN F ISSN EAKNIETALKSVNFQVL S KN V T+PPMPYITSTLQQDAA KFNFPATYTMKLAQKLYEGIQLADG AA
Subjt:  SSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAA

Query:  GLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQ
        GLITYPRTDG HISDEAVKD+ SLIM+R+GQ+FV +SG +YFKKV NAQEA EAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRT+ACQME SITE+I+
Subjt:  GLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQ

Query:  IDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTF
        IDCGLAD+SII+ STCSRVQFRGF+ VFEDPEVHAVKHKDHEESGRDELFRILN LKPGD+LSLLAVEL++HFTQPPPRY+EGTLVKRMEELGIGRPST+
Subjt:  IDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTF

Query:  ATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDY
        AT LKVL+DRNYV+VKS +LHPEFRG IVSAFLCHHFS +T    TA++E KLDNVSAG T+WKRLLRD W Q+SS CKRANNV I+QVEKMLE+KY D+
Subjt:  ATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDY

Query:  LFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSA-EEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKG
        LFS LP+NSR CPSCPDGTLS KV   G+GYYIGCD+ P CK+VAKT +GE EDK P   +    +EPKVIGVHPV NEKI+LKNGPFGFYVQLGEDRKG
Subjt:  LFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSA-EEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKG

Query:  YVPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRPKSP
        YVPKRAS+ EIKD NSITL+VA+DRLRYPI LG HPKDG+PVI+KIARVGFT+RH RTIAS+PK++KP  + LAKALKLLSSS VRR+GRPK P
Subjt:  YVPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRPKSP

A0A5A7T7A4 DNA topoisomerase

0.0e+00

78.82

Show/hide

Query:  LVSSNSSSSIRKASKGLKEKKSRSKKKKEAISSTNDA-------DTKKANLVSSNS-------------SSSIRKASKGLNVKKSRSKKKKEAISSTNDA
        LVSSNSSSSIR+ASKGL EKKS SKKKK+AISSTNDA       D++  +  SSN+             SS+IRKASKGLN KKS SK KKEAISSTNDA
Subjt:  LVSSNSSSSIRKASKGLKEKKSRSKKKKEAISSTNDA-------DTKKANLVSSNS-------------SSSIRKASKGLNVKKSRSKKKKEAISSTNDA

Query:  DVEEVCK--------------DVIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVV
        DVE VCK              DV+QDPKKN T+GTSKDS STK+QSNKKK NSSRNKEATK ANKL QKPNV+VD RGTSQG+TTFKQLYPPMGKSV+VV
Subjt:  DVEEVCK--------------DVIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVV

Query:  ESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGI
        ESV KAKVIQ+YLGDMFVVLPSHGHVRDLAARSGSVRP+DDFIMVWEVPSAAWTHLKSIE+SLNGAENLILASDPDQEGEAIAWHIIEMLQHQ+ALHEGI
Subjt:  ESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGI

Query:  SIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPC
        SIARVVFHEITEASIK+ALQSPRVID N+VQAYLARRALDYLIGFNISPLLW+KLPGC+SPGRVQSAALALICDRE EID+F AQEYWTID++LNQKDPC
Subjt:  SIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPC

Query:  SSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAA
        SSVEDFAVPA LTHFDSKKLN F ISSN EAKNIETALKSVNFQVL S KN V T+PPMPYITSTLQQDAA KFNFPATYTMKLAQKLYEGIQLADG AA
Subjt:  SSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAA

Query:  GLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQ
        GLITYPRTDG HISDEAVKD+ SLIM+R+GQ+FV +SG +YFKKV NAQEA EAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRT+ACQME SITE+I+
Subjt:  GLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQ

Query:  IDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTF
        IDCGLAD+SII+ STCSRVQFRGF+ VFEDPEVHAVKHKDHEESGRDELFRILN LKPGD+LSLLAVEL++HFTQPPPRY+EGTLVKRMEELGIGRPST+
Subjt:  IDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTF

Query:  ATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDY
        AT LKVL+DRNYV+VKS +LHPEFRG IVSAFLCHHFS +T    TA++E KLDNVSAG T+WKRLLRD W Q+SS CKRANNV I+QVEKMLE+KY D+
Subjt:  ATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDY

Query:  LFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSA-EEPKVIGVHPVLNEK--------------------
        LFS LP+NSR CPSCPDGTLS KV   G+GYYIGCD+ P CK+VAKT +GE EDK P   +    +EPKVIGVHPV NEK                    
Subjt:  LFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSA-EEPKVIGVHPVLNEK--------------------

Query:  ------IILKNGPFGFYVQLGEDRKGYVPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLA
              I+LKNGPFGFYVQLGEDRKGYVPKRAS+ EIKD NSITL+VA+DRLRYPI LG HPKDG+PVI+KIARVGFT+RH RTIAS+PK++KP  + LA
Subjt:  ------IILKNGPFGFYVQLGEDRKGYVPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLA

Query:  KALKLLSSSAVRRVGRPKSP
        KALKLLSSS VRR+GRPK P
Subjt:  KALKLLSSSAVRRVGRPKSP

A0A6J1IF86 Omega-protein

0.0e+00

78.34

Show/hide

Query:  SSNSSSS-----IRKASKGLKEKKSRSKKKKEAISS--------TNDAD-----TKKANLVSSNSSSSIRKASKGLNVKKSRSKKKKEAISSTNDADVEE
        +SN +S+     + K  KG K   +  KK+  A  S        TN +D     TK+A LVSSNSSSS+RKASKGL  K S SKKKKEAIS TN +DVE 
Subjt:  SSNSSSS-----IRKASKGLKEKKSRSKKKKEAISS--------TNDAD-----TKKANLVSSNSSSSIRKASKGLNVKKSRSKKKKEAISSTNDADVEE

Query:  VCKD--------------VIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVVESVV
        VCKD              V+Q+PKK  + GT+K S ST +QSNKKK NSSR KEA KDA+KLPQKPN+VVDARG SQG TT KQLYPPMGKSVMVVESV 
Subjt:  VCKD--------------VIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVVESVV

Query:  KAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGISIAR
        KAKVIQNYLGDMF VLPSHGHVRDLAARSGSVRPDDDF MVWEVPSAAWTHLKS++VSLNGAENLILASDPD+EGEAIAWHIIEMLQ Q+ALHEGISIAR
Subjt:  KAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGISIAR

Query:  VVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPCSSVE
        VVFHEITEASIK+ALQSPR IDAN+VQAYLARRALDYLIGFNISPLLWRKLPGCQS GRVQSAALALICDRE+EI+EF  QEYWTIDIELNQKDPCSSVE
Subjt:  VVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPCSSVE

Query:  DFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAAGLIT
        +F VPA LTHFDSKKLN FAISS TEAKNIETALKSVNFQVL S+KN+V  +PPMPYITSTLQQDAANK NFPA+YTMKLAQKLYEGIQLADG AAGLIT
Subjt:  DFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAAGLIT

Query:  YPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQIDCG
        YPRTDG HISDEAVKD+RSLI +RYG NFV ES R+YFKKV NAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRT+ACQME SITEQIQID G
Subjt:  YPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQIDCG

Query:  LADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTFATTL
        LAD+SII  STCSRVQFRGFQEVFEDPEV A++HKDHEE+ RDELFRILNALK GDQLSL AVELKQHFTQPPPRYSEGTLVK+MEELGIGRPST+A+TL
Subjt:  LADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTFATTL

Query:  KVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDYLFSL
        KVLQDRNY+SVKSRVLHPEFRG +VSAFLCHHFSEVT   FTA+ME +LDNVSAG T+WK LLRD+WT+ S+ C+RANNV IHQVEKMLE+KYED+LFS 
Subjt:  KVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDYLFSL

Query:  LPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKGYVPKR
        LPDN RTCPSC +GTL  KV R+G GY+IGCDQHPRCK++AKTLYGE E++    +  S EEPK++G+HPV +EKI+LK+GP+GFYVQLGEDRKGY+PKR
Subjt:  LPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKGYVPKR

Query:  ASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRPKS
         SV +IKDV SITLE A++ LRYPI LGNHPKDG  V+IKI + GFT+RHRRTIAS+PKNLKPND+DLAKAL+LLSS  VRR GRPKS
Subjt:  ASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRPKS

A0A6J1IMZ7 Omega-protein

0.0e+00

78.34

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Query:  SSNSSSS-----IRKASKGLKEKKSRSKKKKEAISS--------TNDAD-----TKKANLVSSNSSSSIRKASKGLNVKKSRSKKKKEAISSTNDADVEE
        +SN +S+     + K  KG K   +  KK+  A  S        TN +D     TK+A LVSSNSSSS+RKASKGL  K S SKKKKEAIS TN +DVE 
Subjt:  SSNSSSS-----IRKASKGLKEKKSRSKKKKEAISS--------TNDAD-----TKKANLVSSNSSSSIRKASKGLNVKKSRSKKKKEAISSTNDADVEE

Query:  VCKD--------------VIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVVESVV
        VCKD              V+Q+PKK  + GT+K S ST +QSNKKK NSSR KEA KDA+KLPQKPN+VVDARG SQG TT KQLYPPMGKSVMVVESV 
Subjt:  VCKD--------------VIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVVESVV

Query:  KAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGISIAR
        KAKVIQNYLGDMF VLPSHGHVRDLAARSGSVRPDDDF MVWEVPSAAWTHLKS++VSLNGAENLILASDPD+EGEAIAWHIIEMLQ Q+ALHEGISIAR
Subjt:  KAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGISIAR

Query:  VVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPCSSVE
        VVFHEITEASIK+ALQSPR IDAN+VQAYLARRALDYLIGFNISPLLWRKLPGCQS GRVQSAALALICDRE+EI+EF  QEYWTIDIELNQKDPCSSVE
Subjt:  VVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPCSSVE

Query:  DFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAAGLIT
        +F VPA LTHFDSKKLN FAISS TEAKNIETALKSVNFQVL S+KN+V  +PPMPYITSTLQQDAANK NFPA+YTMKLAQKLYEGIQLADG AAGLIT
Subjt:  DFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAAGLIT

Query:  YPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQIDCG
        YPRTDG HISDEAVKD+RSLI +RYG NFV ES R+YFKKV NAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRT+ACQME SITEQIQID G
Subjt:  YPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQIDCG

Query:  LADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTFATTL
        LAD+SII  STCSRVQFRGFQEVFEDPEV A++HKDHEE+ RDELFRILNALK GDQLSL AVELKQHFTQPPPRYSEGTLVK+MEELGIGRPST+A+TL
Subjt:  LADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTFATTL

Query:  KVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDYLFSL
        KVLQDRNY+SVKSRVLHPEFRG +VSAFLCHHFSEVT   FTA+ME +LDNVSAG T+WK LLRD+WT+ S+ C+RANNV IHQVEKMLE+KYED+LFS 
Subjt:  KVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDYLFSL

Query:  LPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKGYVPKR
        LPDN RTCPSC +GTL  KV R+G GY+IGCDQHPRCK++AKTLYGE E++    +  S EEPK++G+HPV +EKI+LK+GP+GFYVQLGEDRKGY+PKR
Subjt:  LPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKGYVPKR

Query:  ASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRPKS
         SV +IKDV SITLE A++ LRYPI LGNHPKDG  V+IKI + GFT+RHRRTIAS+PKNLKPND+DLAKAL+LLSS  VRR GRPKS
Subjt:  ASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRPKS

SwissProt top hits

e value

%identity

Alignment

Q1RIM1 DNA topoisomerase 1

5.3e-171

41.07

Show/hide

Query:  VMVVESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNAL
        +++VES  KAK I  YLGD F V+ S GH+RDL ++ GSV PD++F M +++   A  ++ +I      AE++ LA+DPD+EGE+I+WHI E+++ +N +
Subjt:  VMVVESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNAL

Query:  HEGISIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQ
               RV F+EIT+ +I +A+++PR +D N+V A  ARRALDYL+GF +SPLLWRKLPGC+S GRVQS AL LIC+RE EI+ F ++EYW I +++  
Subjt:  HEGISIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQ

Query:  KDPCSSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLAD
            S+ E F   A+LTH + +KL  F+I+++ EAK++   LKS NF V + EK +    P  P+ITS+LQQ+AA K  F A  TM++AQKLYEG+ +  
Subjt:  KDPCSSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLAD

Query:  GTAAGLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSIT
         T  GLITY RTDG  +S++AV ++R LI + YG  ++P S R Y  KV NAQEAHEAIRPT++  +P+ L   L++D +KLY LIW RT+ACQME+ I 
Subjt:  GTAAGLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSIT

Query:  EQIQIDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGR
        + +       +K  ++ +  S + F GF +V+ +    ++  +  EE+      ++L  LK  + L    +   QHFT+PPPRYSE +LVK++EELGIGR
Subjt:  EQIQIDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGR

Query:  PSTFATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEK
        PST+AT L VLQDR YV+++ +   PE  G +V+ FL   F +     FTA +E +LD ++AG  +WK  L +FW   +   +  N   I ++   +++ 
Subjt:  PSTFATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEK

Query:  YEDYLFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGED
         + ++F    D S+ CPSC  G LSLK+ +FG   ++ C  +P C      + G   ++    ++    E KV+G       +I LK GP+G Y+Q GE 
Subjt:  YEDYLFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGED

Query:  RKGYV-PKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLL
            + PKR+ +    + N ITL++A+  L  P+ +GNH + G  V++   + G  I++     SIPK     ++ L  A+KL+
Subjt:  RKGYV-PKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLL

Q4UM42 DNA topoisomerase 1

2.1e-172

41.32

Show/hide

Query:  VMVVESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNAL
        +++VES  KAK I  YLGD F V+ S GH+RDL ++ GSV PD++F M +++   A  ++ +I      A+ + LA+DPD+EGEAI+WH+ E+++ +N +
Subjt:  VMVVESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNAL

Query:  HEGISIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQ
               RV F+EIT+ +I +A+++PR +DAN+V A  ARRALDYL+GF +SPLLWRKLPGC+S GRVQS AL LIC+RE EI+ F ++EYW I +++  
Subjt:  HEGISIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQ

Query:  KDPCSSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLAD
            S+ E F   A+LTH + +KL  F+I +  +AK++   LKS NF V + EK +    P  P+ITS+LQQ+AA K  F A  TM++AQKLYEG+ +  
Subjt:  KDPCSSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLAD

Query:  GTAAGLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSIT
         T  GLITY RTDG  +S++A+ D+R LI + YG  ++P S R Y  KV NAQEAHEAIRPT++   P  L   L++D +KLY LIW RT+ACQME+ I 
Subjt:  GTAAGLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSIT

Query:  EQIQIDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGR
        + +       +K  ++ +  S + F GF +V+ +    +V  +  EE+      ++L  LK  + L    +   QHFT+PPPRYSE +LVK++EELGIGR
Subjt:  EQIQIDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGR

Query:  PSTFATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEK
        PST+A+ L VLQDR YVS++ +   PE  G +V+ FL   F +     FTA +E +LD ++AG  +WK  L +FW+  +   +  N  +I ++   +++ 
Subjt:  PSTFATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEK

Query:  YEDYLFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGED
         + +LFS   + S+ CPSC  G LSLK+ +FG   ++ C  +P C      + G   ++      ++  E KV+G       +I LK GP+G YVQLGE 
Subjt:  YEDYLFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGED

Query:  RKGYVPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVR
             PKR+ V    + N ITLE+A+  L  P+ +G H   G  ++I   + G  I++     SIPK     ++ L  A+KL+  +  +
Subjt:  RKGYVPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVR

Q68X45 DNA topoisomerase 1

5.4e-168

40.43

Show/hide

Query:  VMVVESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNAL
        +++VES  KAK I  YLGD F V+ S GH+RDL ++ GSV PD +F M +++   A  ++ +I      AE + LA+DPD+EGE+I+WH+ E+++ +N +
Subjt:  VMVVESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNAL

Query:  HEGISIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQ
               RV F+EIT+ +I +A+++PR +D N+V A  ARRALDYL+GF +SPLLWRKLPGC+S GRVQS AL LICDRE EI+ F A+EYW I +++  
Subjt:  HEGISIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQ

Query:  KDPCSSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLAD
            S+ E F   A+LTH + +KL  F+I +  EAK++   LK   F V + EK +    P  P+ITS+LQQ+AA K  F A  TM++AQKLYEG+ +  
Subjt:  KDPCSSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLAD

Query:  GTAAGLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSIT
         T  GLITY RTDG  +S++A+ D+R LI + YG  ++P + R Y  KV NAQEAHEAIRPT++   P  L   L++D +KLY LIW RT+ACQME+ I 
Subjt:  GTAAGLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSIT

Query:  EQIQIDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGR
        + +  +    +K  ++ +  S + F GF +V+ +    ++  +D E++      ++L  LK  + +    V   +HFT+PPPRYSE +LVK++EELGIGR
Subjt:  EQIQIDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGR

Query:  PSTFATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEK
        PST+A+ L VLQDR YV+++ +   PE  G +V+ FL   F +     FTA +E +LD ++AG  +WK  L +FW+  ++  +  N  +I ++   L++ 
Subjt:  PSTFATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEK

Query:  YEDYLFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGED
         + +LF    + S+ CPSC  G LSLK+ +FG   ++ C  +P C      + G   ++      +   + K++G       +I LK GP+G Y+QLGE 
Subjt:  YEDYLFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGED

Query:  RKGYVPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVR
             PKR  V      + ITLEVA+  L  P+ +G H   G  +II  ++ G  I++     S+PK     +++L  A+KL+ ++  +
Subjt:  RKGYVPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVR

Q92IH1 DNA topoisomerase 1

2.1e-167

40.05

Show/hide

Query:  VMVVESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNAL
        +++VES  KAK I  YLGD F V+ S GH+RDL ++ GSV PD++F M +++   A  ++ +I      A+ + LA+DPD+EGE+I+WH+ E+++ +N +
Subjt:  VMVVESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNAL

Query:  HEGISIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQ
               RV F+EIT+ +I +A+++PR +D N+V A  ARRALDYL+GF +SPLLWRKLPGC+S GRVQS AL LIC+RE EI+ F ++EYW I +++  
Subjt:  HEGISIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQ

Query:  KDPCSSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLAD
            S+ E F   A+LTH + +KL  F+I +   AK++   LKS  F V + EK +    P  P+ITS+LQQ+AA K  F A  TM++AQKLYEG+ +  
Subjt:  KDPCSSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLAD

Query:  GTAAGLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSIT
         T  GLITY RTDG  +S++A+ D+R LI + YG  ++P S R Y  KV NAQEAHEAIRPT++   P  L   LD+D +KLY LIW RT+ACQME+ I 
Subjt:  GTAAGLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSIT

Query:  EQIQIDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGR
        + +  +    +K  ++ +  S + F GF +V+          ++  +   +E  ++L  LK  + L   AV   QHFT+PPPRYSE +LVK++EELGIGR
Subjt:  EQIQIDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGR

Query:  PSTFATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEK
        PST+A+ L VLQDR YV+++ +   PE  G +V+ FL   F +     FTA +E +LD ++AG  +WK  L +FW+  +   +  N  +I ++   +++ 
Subjt:  PSTFATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEK

Query:  YEDYLFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGED
         + +LF    + S+ CPSC  G LSLK+ +FG   ++ C  +P C      + G   ++      +   E KV+G       +I LK GP+G Y+QLG+ 
Subjt:  YEDYLFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGED

Query:  RKGYVPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVR
             PKR+ V    + N ITL++A+  L  P+ +G H      ++I   + G  I++     S+ K     ++ L  A+KL+  +  +
Subjt:  RKGYVPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVR

Q9ZDK2 DNA topoisomerase 1

4.2e-168

39.92

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Query:  VMVVESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNAL
        +++VES  KAK I  YLGD F V+ S GH+RDL ++ GSV PD +F+M +++   A  ++ +I      AE + LA+DPD+EGE+I+WH+ E+++ +N +
Subjt:  VMVVESVVKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNAL

Query:  HEGISIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQ
               RV F+EIT+ +I NA+ +PR +D N+V A  ARRALDYL+GF +SPLLWRKLPGC+S GRVQS AL LICDRE EI+ F ++EYW I +++  
Subjt:  HEGISIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQ

Query:  KDPCSSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLAD
         +      +    A+LTH + +KL  F+I +  EAK++   LK   F V + EK +    P  P+ITS+LQQ+AA K  F A  TM++AQKLYEG+ +  
Subjt:  KDPCSSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLAD

Query:  GTAAGLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSIT
         T  GLITY RTDG  +S++A+ D+R LI + YG  ++P   R Y  KV NAQEAHEAIRPT++   P  L   L++D +KLY LIW RT+ACQME+ I 
Subjt:  GTAAGLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSIT

Query:  EQIQIDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGR
        + +  +    +K  ++ +  S + F GF +V+ +    ++  +D E++      ++L  LK  + +    V   +HFT+PPPRYSE +LVK++EELGIGR
Subjt:  EQIQIDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGR

Query:  PSTFATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEK
        PST+A+ L VLQDR YV+++ +   PE  G +V+ FL   F +     FTA +E +LD ++AG  +WK  L +FW   +   +  N  +I ++   L++ 
Subjt:  PSTFATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEK

Query:  YEDYLFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGED
         + +LF      S+ CPSC  G LSLK+ +FG   ++ C  +P C      + G   ++      +   + K++G       +I LK GP+G Y+QLGE 
Subjt:  YEDYLFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGED

Query:  RKGYVPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVR
             PKR  V      + ITLE+A+  L  P+ +G H   G  +II  ++ G  I++     S+PK     ++ L  A+KL+ ++  +
Subjt:  RKGYVPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVR

Arabidopsis top hits

e value

%identity

Alignment

AT4G31210.1 DNA topoisomerase, type IA, core

3.1e-312

57.44

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Query:  RKASKGLKEKKSRSKKKKEAISSTNDADTKKANLVSSNSSSSIRKASKGLNVKKSRSK-----KKKEAISSTNDADVEEVCKD--VIQDPKKNGTRGTSK
        +K +K  K+    +  + E ++ST       ++ + +  S++   AS G      +SK     KK E  SS+    +E V  D   I  PK   +   ++
Subjt:  RKASKGLKEKKSRSKKKKEAISSTNDADTKKANLVSSNSSSSIRKASKGLNVKKSRSK-----KKKEAISSTNDADVEEVCKD--VIQDPKKNGTRGTSK

Query:  DSASTKRQSNKK----------KLNSSRNKEATKD--ANKLPQKPNVVVDARGT--SQGRTTFKQLYPPMGKSVMVVESVVKAKVIQNYLGDMFVVLPSH
         S+S K++  K             NS   ++  K   A+K P++  V    + +   +G+   K LYPP GKSV+VVES+ KAK+IQ YLGDM+ VLPS+
Subjt:  DSASTKRQSNKK----------KLNSSRNKEATKD--ANKLPQKPNVVVDARGT--SQGRTTFKQLYPPMGKSVMVVESVVKAKVIQNYLGDMFVVLPSH

Query:  GHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGISIARVVFHEITEASIKNALQSPR
        GH+RDLA RSGSVRPDDDF MVWEVPS+AWTH+KSI+V+LNGAENLILASDPD+EGEAIAWHIIEMLQ Q ALHE +++ARVVFHEITE++IK+ALQSPR
Subjt:  GHVRDLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGISIARVVFHEITEASIKNALQSPR

Query:  VIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPCSSVEDFAVPARLTHFDSKKLNPF
         ID ++V AYLARRALDYLIGFNISPLLWRKLPGC S GRVQSAALAL+CDRE EID F  QEYWT+ I++  KD  ++       A LT  +SK+LN  
Subjt:  VIDANMVQAYLARRALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPCSSVEDFAVPARLTHFDSKKLNPF

Query:  AISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAAGLITYPRTDGPHISDEAVKDVRS
        +ISS   A++IE  +KS  F V  ++ +    +PP PYITSTLQQDAANK +F   +TMKLAQKLYEG+QL+DG +AGLITY RTDG HI+DEA+KD++S
Subjt:  AISSNTEAKNIETALKSVNFQVLRSEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAAGLITYPRTDGPHISDEAVKDVRS

Query:  LIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQIDCGLADKSIISGSTCSRVQFRG
        L+  RYG+NF  +S R+YFKKV NAQEAHEAIRPTD++RLPS +   LD DS KLY+LIW R VACQME +   QIQ+D G A +SII  S+CS+V+F G
Subjt:  LIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQIDCGLADKSIISGSTCSRVQFRG

Query:  FQEVFEDPEVHAVKHKDHEESG-RDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTFATTLKVLQDRNYVSVKSRVLHP
        +Q V+EDPE  A+K+ D+++S  R+E F+ L++LK GD L +  VELKQH TQ PPRYSEG+LVK++EELGIGRPST+A+  +VLQ R YV++K+RVL+P
Subjt:  FQEVFEDPEVHAVKHKDHEESG-RDELFRILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTFATTLKVLQDRNYVSVKSRVLHP

Query:  EFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDYLFSLLPDNSRTCPSCPDGTLSL
        EFR  +VSAFL H+F+E+T   FTA+ME +LDNVS G T+WK LLRD+WT+ S+ CKR  NVQ  QVEKMLE+KYED LFSLLP  SRTCPSC +GTLS 
Subjt:  EFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKMLEEKYEDYLFSLLPDNSRTCPSCPDGTLSL

Query:  KVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKGYVPKRASVFEIKDVNSITLEVAV
        K  +FG GY+IGCDQHP CK +AKTLYGE ED+   P  +  EEPK++G+HP  +EK+ILK GP+G YVQLGED+KG+ PKRA+   IKDVNSITLE A+
Subjt:  KVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPFGFYVQLGEDRKGYVPKRASVFEIKDVNSITLEVAV

Query:  DRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRP
        + LRYP+ LG HP+DG+PV++K+++ GFTI+HRR +A++PKN +P ++ L +A+KLLS   VR+ GRP
Subjt:  DRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRP

AT5G63920.1 topoisomerase 3alpha

1.4e-25

22.13

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Query:  KSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGISIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNIS---PLLWR
        K++E     ++ L+L  D D+EGE IA+ ++++ +   A+   + I R  F  + +  I  A+Q+ R  +    +A  AR+ +D  IG + +    +L R
Subjt:  KSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGISIARVVFHEITEASIKNALQSPRVIDANMVQAYLARRALDYLIGFNIS---PLLWR

Query:  KLPGCQSPGRVQS----------AALALICDREMEIDEFHAQEYWTIDIELNQKDPCSSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNF
              S G  +S            L  I +R  EI     +E+WTI+        CS   +      L  F+  + + F  +S       E  ++    
Subjt:  KLPGCQSPGRVQS----------AALALICDREMEIDEFHAQEYWTIDIELNQKDPCSSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNF

Query:  QVLR-SEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAAGLITYPRTDGPHISDEAVKDVRSLIMRR--------YGQNFV
         V+      E +  PP P  T  L++ A+  F   + +TMK+A++LY+         AG I+YPRT+    S     D+R+++  +        Y Q  +
Subjt:  QVLR-SEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAAGLITYPRTDGPHISDEAVKDVRSLIMRR--------YGQNFV

Query:  PESGRQYFKKVNNAQE--AHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQIDCGLADKSIISGSTCSRVQFRGFQEVFEDPE
           G  +    N   +  AH  I PT      S        D   +Y L+    +AC  + ++  +  ++  +A +   +                    
Subjt:  PESGRQYFKKVNNAQE--AHEAIRPTDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQIDCGLADKSIISGSTCSRVQFRGFQEVFEDPE

Query:  VHAVKHKDHEESGRDELF--RILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTFATTLKVLQDRNYVSVKSRV-LHPEFRGLIV
          A+  K++ E  R E +   ++   + G Q     + L    T+PPP   E  L+  M++ GIG  +T    +K L DR Y +  +     P   G  +
Subjt:  VHAVKHKDHEESGRDELF--RILNALKPGDQLSLLAVELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTFATTLKVLQDRNYVSVKSRV-LHPEFRGLIV

Query:  SAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKML-----EEKYEDYLFSLLPDNSRTCPSCPDGTLSLKV
                 E+      A ME  ++ VS G      +L     QM +C   A   +   +E M          ++       +  R C  C +  ++L+ 
Subjt:  SAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSCCKRANNVQIHQVEKML-----EEKYEDYLFSLLPDNSRTCPSCPDGTLSLKV

Query:  KRFGVGYYIGCDQHPRCKH
         R G  + +GC  +P+C++
Subjt:  KRFGVGYYIGCDQHPRCKH

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGAAAAGAAGTCTCGGAGCAAGAAAAAGAAGGAAGCTATTTCTTCAACCAATGATGCAGATACAAAGAAGGCGAATCTATCTAGTTTCATCTAATTCTTCTTCATCCAT
TAGGAAAGCATCCAAGGGTTTGAAGGAAAAGAAGTCTCGAAGCAAGAAAAAAAAGGAAGCTATTTCTTCAACCAATGATGCAGATACAAAGAAGGCGAATCTAGTTTCAT
CTAATTCTTCTTCATCCATTAGGAAAGCATCCAAGGGTTTGAATGTAAAGAAATCTCGGAGCAAGAAAAAGAAGGAAGCTATTTCTTCAACCAATGATGCAGATGTTGAA
GAGGTATGCAAGGATGTTATACAAGATCCTAAGAAAAATGGAACCAGGGGTACTTCCAAAGATTCTGCTTCAACCAAACGACAATCCAATAAGAAAAAACTCAACTCCAG
CAGAAACAAAGAAGCTACAAAAGACGCTAATAAATTGCCGCAGAAGCCAAACGTCGTAGTGGATGCAAGGGGGACATCTCAGGGAAGGACCACTTTCAAGCAGCTATATC
CCCCAATGGGAAAATCTGTTATGGTAGTGGAATCTGTTGTAAAGGCAAAAGTTATTCAGAATTATCTTGGTGATATGTTTGTGGTGCTACCTAGCCATGGCCACGTTAGA
GACTTGGCTGCAAGGTCAGGATCTGTAAGACCTGATGATGACTTCATTATGGTGTGGGAGGTTCCTTCTGCTGCCTGGACTCATCTCAAAAGCATTGAAGTTTCCTTAAA
TGGAGCAGAGAACCTTATTCTTGCATCTGATCCAGATCAAGAAGGTGAAGCTATTGCTTGGCATATAATTGAGATGTTGCAGCACCAGAATGCTCTACATGAAGGTATTA
GCATAGCAAGGGTTGTTTTTCATGAAATAACTGAGGCTTCTATCAAGAATGCCCTGCAATCTCCTAGAGTAATTGATGCAAACATGGTCCAGGCTTACCTTGCACGGCGT
GCTTTAGATTATTTGATTGGATTTAATATTTCACCATTATTATGGAGGAAATTACCAGGTTGCCAATCACCTGGGCGTGTTCAATCCGCTGCACTCGCCCTAATATGTGA
CAGAGAAATGGAAATTGATGAGTTTCATGCACAAGAATATTGGACTATTGACATTGAGTTGAACCAAAAAGATCCTTGTTCTTCAGTGGAAGATTTTGCAGTCCCTGCAC
GTTTGACCCATTTTGATTCTAAGAAGTTAAATCCGTTTGCAATCAGCTCCAACACGGAGGCAAAGAATATAGAAACTGCGCTGAAATCAGTAAATTTTCAAGTGCTTAGG
TCTGAAAAGAATGAAGTGTGGACAGACCCTCCAATGCCATATATAACATCTACACTTCAGCAAGATGCAGCAAACAAATTTAATTTCCCTGCAACTTACACAATGAAGCT
TGCCCAGAAACTTTATGAGGGAATTCAACTGGCGGATGGAACGGCAGCTGGCCTAATAACTTATCCAAGAACGGATGGGCCACATATCTCTGATGAAGCTGTTAAGGACG
TTCGCTCCCTGATTATGCGAAGATATGGGCAGAATTTTGTACCCGAAAGTGGACGACAATATTTTAAGAAAGTGAACAATGCTCAAGAGGCTCATGAAGCAATTAGACCC
ACTGATGTGCAACGATTACCCTCAATGCTAGTGGGAACACTTGACGAAGATTCTCACAAACTATACTCTCTTATTTGGCTCAGAACGGTGGCATGTCAAATGGAATCTTC
TATCACTGAACAGATTCAAATTGACTGTGGACTTGCGGATAAATCCATCATTTCCGGATCTACATGCTCAAGAGTTCAATTTCGTGGGTTTCAAGAAGTTTTTGAGGATC
CAGAAGTTCATGCAGTCAAACATAAAGACCATGAAGAAAGTGGACGGGATGAACTGTTCAGAATTCTGAATGCATTGAAGCCAGGGGATCAATTGTCTCTACTTGCTGTT
GAACTCAAGCAACATTTTACCCAGCCCCCACCCCGCTATTCTGAGGGAACATTGGTTAAAAGGATGGAGGAGCTAGGGATTGGAAGACCTTCCACATTTGCAACCACACT
AAAAGTTTTACAGGACAGGAACTATGTGTCAGTGAAAAGTCGTGTTCTACATCCAGAGTTTCGTGGGCTCATAGTATCGGCATTTCTTTGTCATCATTTCTCTGAGGTCA
CCGGTTGTAGGTTTACTGCAAACATGGAAAAGAAGCTTGATAATGTCTCGGCTGGATCAACTAAATGGAAACGCCTCCTAAGAGATTTTTGGACCCAGATGAGCTCATGT
TGTAAACGTGCTAATAATGTTCAGATTCATCAGGTGGAAAAGATGTTGGAGGAGAAATATGAGGACTACTTATTTTCTTTGCTTCCTGATAATTCCAGAACATGTCCAAG
TTGTCCGGATGGCACTCTGAGCCTCAAAGTTAAGCGGTTTGGTGTTGGCTATTACATAGGTTGTGATCAACACCCAAGATGCAAGCATGTCGCAAAAACATTATATGGTG
AGGGTGAAGATAAAGGTCCTACTCCAAGTGAGAGCAGTGCGGAAGAGCCAAAGGTTATTGGTGTTCATCCAGTTTTGAATGAAAAGATTATTTTGAAGAATGGTCCATTT
GGGTTTTATGTACAACTTGGTGAGGACAGGAAGGGTTACGTTCCCAAAAGAGCATCTGTTTTTGAGATAAAGGACGTGAACTCTATTACTCTCGAGGTTGCCGTTGATCG
TTTACGCTACCCAATTAATTTGGGAAATCATCCAAAGGATGGCCGACCGGTGATAATAAAGATTGCAAGAGTTGGATTCACAATTAGACATCGACGCACGATAGCTTCCA
TTCCTAAGAATTTGAAGCCAAACGACATCGATTTAGCGAAAGCATTGAAGCTTCTGTCAAGTAGCGCAGTTAGAAGGGTTGGGCGACCTAAAAGCCCATTCCAAGGCTGA

mRNA sequence

Show/hide mRNA sequence

Protein sequence

Show/hide protein sequence

MKRSLGARKRRKLFLQPMMQIQRRRIYLVSSNSSSSIRKASKGLKEKKSRSKKKKEAISSTNDADTKKANLVSSNSSSSIRKASKGLNVKKSRSKKKKEAISSTNDADVE
EVCKDVIQDPKKNGTRGTSKDSASTKRQSNKKKLNSSRNKEATKDANKLPQKPNVVVDARGTSQGRTTFKQLYPPMGKSVMVVESVVKAKVIQNYLGDMFVVLPSHGHVR
DLAARSGSVRPDDDFIMVWEVPSAAWTHLKSIEVSLNGAENLILASDPDQEGEAIAWHIIEMLQHQNALHEGISIARVVFHEITEASIKNALQSPRVIDANMVQAYLARR
ALDYLIGFNISPLLWRKLPGCQSPGRVQSAALALICDREMEIDEFHAQEYWTIDIELNQKDPCSSVEDFAVPARLTHFDSKKLNPFAISSNTEAKNIETALKSVNFQVLR
SEKNEVWTDPPMPYITSTLQQDAANKFNFPATYTMKLAQKLYEGIQLADGTAAGLITYPRTDGPHISDEAVKDVRSLIMRRYGQNFVPESGRQYFKKVNNAQEAHEAIRP
TDVQRLPSMLVGTLDEDSHKLYSLIWLRTVACQMESSITEQIQIDCGLADKSIISGSTCSRVQFRGFQEVFEDPEVHAVKHKDHEESGRDELFRILNALKPGDQLSLLAV
ELKQHFTQPPPRYSEGTLVKRMEELGIGRPSTFATTLKVLQDRNYVSVKSRVLHPEFRGLIVSAFLCHHFSEVTGCRFTANMEKKLDNVSAGSTKWKRLLRDFWTQMSSC
CKRANNVQIHQVEKMLEEKYEDYLFSLLPDNSRTCPSCPDGTLSLKVKRFGVGYYIGCDQHPRCKHVAKTLYGEGEDKGPTPSESSAEEPKVIGVHPVLNEKIILKNGPF
GFYVQLGEDRKGYVPKRASVFEIKDVNSITLEVAVDRLRYPINLGNHPKDGRPVIIKIARVGFTIRHRRTIASIPKNLKPNDIDLAKALKLLSSSAVRRVGRPKSPFQG

PI0019328 (gene) of Melon (PI 482460) v1 genome