CuGenDBv2

Gene ID	PI0021901
Organism	Cucumis metuliferus PI 482460 (Melon (PI 482460) v1)
Description	dCTP pyrophosphatase 1
Genome location	chr01:22423669..22427507
RNA-Seq Expression	PI0021901
Synteny	PI0021901
Gene Ontology terms	GO:0006253 - dCTP catabolic process (biological process) GO:0042262 - DNA protection (biological process) GO:0005829 - cytosol (cellular component) GO:0000287 - magnesium ion binding (molecular function) GO:0047840 - dCTP diphosphatase activity (molecular function)
InterPro domains	IPR004518 - NTP pyrophosphohydrolase MazG, putative catalytic core IPR025984 - dCTP pyrophosphatase 1

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

XP_008458104.1 PREDICTED: dCTP pyrophosphatase 1 [Cucumis melo]

2.5e-59

95.2

Show/hide

Query:  MSSGRKVEEEGDGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDL
        MSS RKVEE+ DGSVSLEVLRMKMAEFSK+RNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDL
Subjt:  MSSGRKVEEEGDGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDL

Query:  SKAALRKLELNAIKYPLHKSINNNN
        SKAALRKLELNAIKYPLHKS +NNN
Subjt:  SKAALRKLELNAIKYPLHKSINNNN

XP_011659219.1 dCTP pyrophosphatase 1 [Cucumis sativus]

9.2e-62

97.6

Show/hide

Query:  MSSGRKVEEEGDGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDL
        MSSGRKVEEEGDGSVSLE LRMKMAEFSK+RNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDL
Subjt:  MSSGRKVEEEGDGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDL

Query:  SKAALRKLELNAIKYPLHKSINNNN
        SKAALRKLELNAIKYPLHKS NNNN
Subjt:  SKAALRKLELNAIKYPLHKSINNNN

XP_022960560.1 dCTP pyrophosphatase 1-like [Cucurbita moschata]

4.4e-48

85.84

Show/hide

Query:  DGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKLELN
        +GSVSLEVL+ KMAEF+KER+WERFHSPRNLLLALVGEVGE+SEIFQWKGEVPKGLPEWEE EK+HLGEELSDVLLYLVRLSDICGIDL++A LRKLELN
Subjt:  DGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKLELN

Query:  AIKYPLHKSINNN
        AIKYP+HK  N++
Subjt:  AIKYPLHKSINNN

XP_023004133.1 dCTP pyrophosphatase 1-like [Cucurbita maxima]

4.4e-48

85.84

Show/hide

Query:  DGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKLELN
        +GSVSLEVL+ KMAEF+KER+WERFHSPRNLLLALVGEVGE+SEIFQWKGEVPKGLPEWEE EK+HLGEELSDVLLYLVRLSDICGIDL++A LRKLELN
Subjt:  DGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKLELN

Query:  AIKYPLHKSINNN
        AIKYP+HK  N++
Subjt:  AIKYPLHKSINNN

XP_038897239.1 dCTP pyrophosphatase 1 [Benincasa hispida]

1.5e-51

92.11

Show/hide

Query:  EEGDGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKL
        +E +GSVSLEVLRMKMAEFSKERNW+RFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEE+EKKHLGEELSDVLLYLVRLSDICGIDL+KAALRKL
Subjt:  EEGDGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKL

Query:  ELNAIKYPLHKSIN
        ELNAIKYPL  S N
Subjt:  ELNAIKYPLHKSIN

TrEMBL top hits

e value

%identity

Alignment

A0A0A0K8I0 dCTP pyrophosphatase 1

4.5e-62

97.6

Show/hide

Query:  MSSGRKVEEEGDGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDL
        MSSGRKVEEEGDGSVSLE LRMKMAEFSK+RNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDL
Subjt:  MSSGRKVEEEGDGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDL

Query:  SKAALRKLELNAIKYPLHKSINNNN
        SKAALRKLELNAIKYPLHKS NNNN
Subjt:  SKAALRKLELNAIKYPLHKSINNNN

A0A1S3C8B7 dCTP pyrophosphatase 1

1.2e-59

95.2

Show/hide

Query:  MSSGRKVEEEGDGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDL
        MSS RKVEE+ DGSVSLEVLRMKMAEFSK+RNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDL
Subjt:  MSSGRKVEEEGDGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDL

Query:  SKAALRKLELNAIKYPLHKSINNNN
        SKAALRKLELNAIKYPLHKS +NNN
Subjt:  SKAALRKLELNAIKYPLHKSINNNN

A0A6J1H9F3 dCTP pyrophosphatase 1

2.2e-48

85.84

Show/hide

Query:  DGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKLELN
        +GSVSLEVL+ KMAEF+KER+WERFHSPRNLLLALVGEVGE+SEIFQWKGEVPKGLPEWEE EK+HLGEELSDVLLYLVRLSDICGIDL++A LRKLELN
Subjt:  DGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKLELN

Query:  AIKYPLHKSINNN
        AIKYP+HK  N++
Subjt:  AIKYPLHKSINNN

A0A6J1KYL5 dCTP pyrophosphatase 1

2.2e-48

85.84

Show/hide

Query:  DGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKLELN
        +GSVSLEVL+ KMAEF+KER+WERFHSPRNLLLALVGEVGE+SEIFQWKGEVPKGLPEWEE EK+HLGEELSDVLLYLVRLSDICGIDL++A LRKLELN
Subjt:  DGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKLELN

Query:  AIKYPLHKSINNN
        AIKYP+HK  N++
Subjt:  AIKYPLHKSINNN

A0A6P6A1W6 dCTP pyrophosphatase 1

3.7e-48

82.05

Show/hide

Query:  EEGDGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKL
        EEGD SVSL++L+ KMA F+KER+W++FHSPRNLLLALVGEVGELSEIFQWKGEVPKGLP+W+E+EK HLGEELSDVLLYLVRLSDICGIDL KAALRK+
Subjt:  EEGDGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKL

Query:  ELNAIKYPLHKSINNNN
        ELNAIKYP  K   NNN
Subjt:  ELNAIKYPLHKSINNNN

SwissProt top hits

e value

%identity

Alignment

Q32KY6 dCTP pyrophosphatase 1

8.5e-26

54.29

Show/hide

Query:  SLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKLELNAIKY
        +LE +R   AEF+ ER+WE+FH PRNLLLALVGEVGEL+E+FQWK +   G   W   E+  L EELSD+L+YLV L+  C +DL +A L K++ N  +Y
Subjt:  SLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKLELNAIKY

Query:  PLHKS
        P+H S
Subjt:  PLHKS

Q91VC0 dCTP pyrophosphatase 1

7.7e-27

54.29

Show/hide

Query:  SLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKLELNAIKY
        +LE +R   AEF+ ER+WE+FH PRNLLLALVGEVGEL+E+FQWK +   G   W+  E+  L EELSDVL+YLV L+  C +DL +A + K++ N  +Y
Subjt:  SLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKLELNAIKY

Query:  PLHKS
        P+H S
Subjt:  PLHKS

Q9H773 dCTP pyrophosphatase 1

1.4e-25

55.34

Show/hide

Query:  SLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKLELNAIKY
        +LE +R   AEF+ ER+WE+FH PRNLLLALVGEVGEL+E+FQWK +   G   W   E+  L EELSDVL+YLV L+  C +DL  A L K+++N  +Y
Subjt:  SLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKLELNAIKY

Query:  PLH
        P H
Subjt:  PLH

Q9QY93 dCTP pyrophosphatase 1

2.2e-26

54.29

Show/hide

Query:  SLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKLELNAIKY
        +LE +R   AEF+ ER+WE+FH PRNLLLALVGEVGEL+E+FQWK +   G   W   E+  L EELSDVL+YLV L+  C +DL +A + K++ N  +Y
Subjt:  SLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKLELNAIKY

Query:  PLHKS
        P+H S
Subjt:  PLHKS

Arabidopsis top hits

e value

%identity

Alignment

AT3G25400.1 CONTAINS InterPro DOMAIN/s: NTP Pyrophosphohydrolase MazG-related, RS21-C6 (InterPro:IPR011394), EAR (InterPro:IPR009039), NTP pyrophosphohydrolase MazG, putative catalytic core (InterPro:IPR004518); Has 1123 Blast hits to 1121 proteins in 452 species: Archae - 22; Bacteria - 753; Metazoa - 81; Fungi - 3; Plants - 83; Viruses - 0; Other Eukaryotes - 181 (source: NCBI BLink).

1.6e-43

69.42

Show/hide

Query:  KVEEEGDGS--VSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKA
        K EE G+    VSL+ L  KM +F+K R+WE++HSPRNLLLA+VGEVGELSEIFQWKGEV +G P+W+E+EK HLGEELSDVLLYLVRLSD CG+DL KA
Subjt:  KVEEEGDGS--VSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKA

Query:  ALRKLELNAIKYPLHKSINNN
        ALRK+ELNAIKYP+ K  +++
Subjt:  ALRKLELNAIKYPLHKSINNN

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGAGTAGTGGAAGAAAGGTGGAAGAGGAAGGAGATGGAAGTGTGAGTTTGGAGGTTTTAAGGATGAAAATGGCTGAATTTTCCAAGGAAAGGAATTGGGAACGCTTTCA
CAGCCCTAGAAATCTCCTTCTTGCTTTGGTGGGAGAAGTGGGAGAATTATCAGAAATATTTCAATGGAAAGGAGAAGTACCAAAAGGGCTGCCAGAATGGGAAGAAGATG
AGAAGAAGCACTTGGGAGAAGAGCTTTCTGATGTGCTTTTGTATTTGGTTAGACTCTCTGATATTTGTGGCATTGATCTTTCTAAAGCTGCCTTAAGGAAATTGGAGCTC
AATGCTATTAAATACCCTCTCCACAAATCCATTAATAATAATAATTAA

mRNA sequence

Show/hide mRNA sequence

AGGCGAAGGGATTAATAATAATGAGTAGTGGAAGAAAGGTGGAAGAGGAAGGAGATGGAAGTGTGAGTTTGGAGGTTTTAAGGATGAAAATGGCTGAATTTTCCAAGGAA
AGGAATTGGGAACGCTTTCACAGCCCTAGAAATCTCCTTCTTGCTTTGGTGGGAGAAGTGGGAGAATTATCAGAAATATTTCAATGGAAAGGAGAAGTACCAAAAGGGCT
GCCAGAATGGGAAGAAGATGAGAAGAAGCACTTGGGAGAAGAGCTTTCTGATGTGCTTTTGTATTTGGTTAGACTCTCTGATATTTGTGGCATTGATCTTTCTAAAGCTG
CCTTAAGGAAATTGGAGCTCAATGCTATTAAATACCCTCTCCACAAATCCATTAATAATAATAATTAATCTTACTCTCTCTCTAATATTTCACTATTTCTCTTCTCTTTT
ATTGTTCCCATCTCGAGATCGGTATAATGTAAATTTAGGTCCCGTTTGATAACGTTATAAATAATAAATTTAATTAGTTTATGGGAAATTATTATAAATATATTTGGTAA
CAATTTCT

Protein sequence

Show/hide protein sequence

MSSGRKVEEEGDGSVSLEVLRMKMAEFSKERNWERFHSPRNLLLALVGEVGELSEIFQWKGEVPKGLPEWEEDEKKHLGEELSDVLLYLVRLSDICGIDLSKAALRKLEL
NAIKYPLHKSINNNN

PI0021901 (gene) of Melon (PI 482460) v1 genome