CuGenDBv2

Gene ID	Sed0003312
Organism	Sechium edule (Chayote v1)
Description	60S ribosomal protein L35-like
Genome location	LG03:336714..338972
RNA-Seq Expression	Sed0003312
Synteny	Sed0003312
Gene Ontology terms	GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (biological process) GO:0006412 - translation (biological process) GO:0022625 - cytosolic large ribosomal subunit (cellular component) GO:0003729 - mRNA binding (molecular function) GO:0003735 - structural constituent of ribosome (molecular function)
InterPro domains	IPR001854 - Ribosomal protein L29/L35 IPR036049 - Ribosomal protein L29/L35 superfamily IPR045059 - 60S ribosomal protein L35

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAG6602348.1 Dirigent protein 25, partial [Cucurbita argyrosperma subsp. sororia]

5.0e-52

97.56

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVV+LSIA+VLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SL+TERQKKKEMYYPLRKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

XP_022923169.1 60S ribosomal protein L35-like [Cucurbita moschata]

5.0e-52

97.56

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVV+LSIA+VLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SL+TERQKKKEMYYPLRKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

XP_022941613.1 60S ribosomal protein L35-like [Cucurbita moschata]

5.0e-52

97.56

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELRQKSKADLLTQLKDLKAEL+LLRVAKVTGGAPNKLSKIKVV+LSIA+VLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SLLTERQKKKEMYYPLRKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

XP_022990488.1 60S ribosomal protein L35-like [Cucurbita maxima]

1.9e-51

96.75

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELR KSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVV+LSIA+VLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SL+TERQKKKEMYYPLRKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

XP_022992073.1 60S ribosomal protein L35-like [Cucurbita maxima]

1.1e-51

97.56

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELRQKSKADLL QLKDLKAELSLLRVAKVTGGAPNKLSKIKVV+LSIA+VLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SLLTERQKKKEMYYPLRKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

TrEMBL top hits

e value

%identity

Alignment

A0A6J1E5L3 60S ribosomal protein L35-like

2.4e-52

97.56

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVV+LSIA+VLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SL+TERQKKKEMYYPLRKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

A0A6J1FSL2 60S ribosomal protein L35-like

2.4e-52

97.56

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELRQKSKADLLTQLKDLKAEL+LLRVAKVTGGAPNKLSKIKVV+LSIA+VLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SLLTERQKKKEMYYPLRKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

A0A6J1JTF2 60S ribosomal protein L35-like

9.2e-52

96.75

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELR KSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVV+LSIA+VLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SL+TERQKKKEMYYPLRKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

A0A6J1JVN4 60S ribosomal protein L35

1.2e-51

96.75

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVV+LSIA+VLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SL TER+KKKEMYYPLRKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

A0A6J1JY13 60S ribosomal protein L35-like

5.4e-52

97.56

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELRQKSKADLL QLKDLKAELSLLRVAKVTGGAPNKLSKIKVV+LSIA+VLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SLLTERQKKKEMYYPLRKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

SwissProt top hits

e value

%identity

Alignment

O80626 60S ribosomal protein L35-2

9.1e-49

87.8

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELR+KSKADL  QLK+ KAEL+LLRVAKVTGGAPNKLSKIKVV+ SIA+VLTVISQKQK+ALREAYK KKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SL TER+KKKEMY+P+RKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

Q9LZ41 60S ribosomal protein L35-4

3.5e-48

86.99

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELR KSK DL  QLK+ KAEL+LLRVAKVTGGAPNKLSKIKVV+ SIA+VLTVISQKQK+ALREAYK KKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SL TER+KKKEMY+P+RKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

Q9M3D2 60S ribosomal protein L35-3

1.0e-47

86.18

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELR KSK+DL TQLK+LKAEL+ LRVAKVTGGAPNKLSKIKVV+ SIA+VLTV SQKQK+ALREAYK KKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SL TER+KKK+MY+P+RKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

Q9M5L0 60S ribosomal protein L35

1.4e-49

88.62

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELRQK+KA+LL QLKDLKAEL+LLRVAKVTGGAPNKLSKIKVV+LSIA+VLTVISQKQK ALREAYK KK LPLDLRPKKTRAIRRRLTKHQ 
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SL TER+KKKEMY+P+RKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

Q9SF53 60S ribosomal protein L35-1

2.0e-48

86.99

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELR+KSK+DL  QLK+LKAEL+LLRVAKVTGGAPNKLSKIKVV+ SIA+VLTV SQKQK+ALREAYK KKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SL TER+KKKEMY+P+RKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

Arabidopsis top hits

e value

%identity

Alignment

AT2G39390.1 Ribosomal L29 family protein

6.5e-50

87.8

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELR+KSKADL  QLK+ KAEL+LLRVAKVTGGAPNKLSKIKVV+ SIA+VLTVISQKQK+ALREAYK KKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SL TER+KKKEMY+P+RKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

AT3G09500.1 Ribosomal L29 family protein

1.4e-49

86.99

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELR+KSK+DL  QLK+LKAEL+LLRVAKVTGGAPNKLSKIKVV+ SIA+VLTV SQKQK+ALREAYK KKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SL TER+KKKEMY+P+RKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

AT3G55170.1 Ribosomal L29 family protein

7.2e-49

86.18

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELR KSK+DL TQLK+LKAEL+ LRVAKVTGGAPNKLSKIKVV+ SIA+VLTV SQKQK+ALREAYK KKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SL TER+KKK+MY+P+RKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

AT3G55170.2 Ribosomal L29 family protein

7.2e-49

86.18

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELR KSK+DL TQLK+LKAEL+ LRVAKVTGGAPNKLSKIKVV+ SIA+VLTV SQKQK+ALREAYK KKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SL TER+KKK+MY+P+RKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

AT5G02610.1 Ribosomal L29 family protein

2.5e-49

86.99

Show/hide

Query:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA
        MARIKVHELR KSK DL  QLK+ KAEL+LLRVAKVTGGAPNKLSKIKVV+ SIA+VLTVISQKQK+ALREAYK KKLLPLDLRPKKTRAIRRRLTKHQA
Subjt:  MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQA

Query:  SLLTERQKKKEMYYPLRKYAIKV
        SL TER+KKKEMY+P+RKYAIKV
Subjt:  SLLTERQKKKEMYYPLRKYAIKV

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGGCGAGGATTAAGGTTCACGAGTTGAGGCAGAAATCGAAGGCGGATCTGTTGACGCAGCTTAAGGATCTTAAGGCGGAGCTTTCTCTCCTTCGAGTCGCTAAAGTCAC
CGGCGGTGCCCCAAACAAGCTATCCAAAATCAAGGTGGTGAAATTGTCGATCGCTCGAGTGTTGACGGTAATTTCTCAGAAGCAGAAGGCCGCATTGAGGGAAGCTTACA
AGAAGAAGAAGCTTTTGCCTCTCGATCTACGACCAAAGAAGACCAGAGCCATTCGTAGAAGGCTCACCAAGCATCAGGCATCTTTGTTAACTGAGAGACAGAAGAAGAAA
GAGATGTACTATCCATTGAGGAAATATGCGATTAAGGTGTAG

mRNA sequence

Show/hide mRNA sequence

AGACAATCCTTTTCCCGCTCAGGGAAACCCTAGTTTTCACAGTAGCACTTCTTCCACCAGGTTCCAAGGGTTTCGCCAAGGGCGGCGCTGAGTCGAAGAGCACGCGCCAA
GAAATGGCGAGGATTAAGGTTCACGAGTTGAGGCAGAAATCGAAGGCGGATCTGTTGACGCAGCTTAAGGATCTTAAGGCGGAGCTTTCTCTCCTTCGAGTCGCTAAAGT
CACCGGCGGTGCCCCAAACAAGCTATCCAAAATCAAGGTGGTGAAATTGTCGATCGCTCGAGTGTTGACGGTAATTTCTCAGAAGCAGAAGGCCGCATTGAGGGAAGCTT
ACAAGAAGAAGAAGCTTTTGCCTCTCGATCTACGACCAAAGAAGACCAGAGCCATTCGTAGAAGGCTCACCAAGCATCAGGCATCTTTGTTAACTGAGAGACAGAAGAAG
AAAGAGATGTACTATCCATTGAGGAAATATGCGATTAAGGTGTAGTAGTATTTTTTGGTCATTTTATATGCAACGGTAGACCAATTTTGTTGACAAGTTTTGTTTCGCGA
TCTCGATAATTTTATGTTGATACACTTGAGGTTTTATCCCTTTAGCCAAGAAGTTCTATTTTCATCGACAATCATATATTTTCATCCTTTAGCTCTGTTTCCACCCACCA
TGCAATTTATAGTTTGATTGATTCAGTTTTGGTGCCTGAGATAGTGATCAACTTTTCAACTTTTGGAACAAAGAACTAATAACAACTGACATTAGCTTCGACAACTTCAA
CAAAGTTGAAAGCAGGAAATAACTTTAAGATCGGTATATTCACTTTTGTCTTATTCATAACTACTAAACACAGGTATTGAATATTGAAATGTGATAACTAACATAACGTT
GTGATTATCATGTTTAGTATTATTAAGGGTTATGATAATATCCTTCCTATTTTAACACACCACACTTTACACTTTACACTGCTCTCTATCGGATCTAAATGTTTTGTGAA
ATTCTATTTGCAGTTTAGCAGTTAGTATTAGTTGAAACTAACAATTGTTTTGGTATGCGTGTGAATAATTTTTTTATTATTTTTAAGAAAAATATCTATTTGGCCTTTGG
GATATAGTTTCAATCCAACCC

Protein sequence

Show/hide protein sequence

MARIKVHELRQKSKADLLTQLKDLKAELSLLRVAKVTGGAPNKLSKIKVVKLSIARVLTVISQKQKAALREAYKKKKLLPLDLRPKKTRAIRRRLTKHQASLLTERQKKK
EMYYPLRKYAIKV

Sed0003312 (gene) of Chayote v1 genome