| GenBank top hits | e value | %identity | Alignment |
|---|
| XP_022152631.1 DNA topoisomerase 2 isoform X1 [Momordica charantia] | 5.4e-271 | 74.65 | Show/hide |
Query: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
M EKKRP+QNS AN D P G KTIEEMYQKKTQ+EHILLRPDTYVGS+E HTQ LWVYEN KMVHR VTYVPGLYKIF+EILVNAADNKQRDPSMD
Subjt: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
Query: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
SVKV IDVE N ISVFNNGDGVPVE+H EEKVY KKTTGGRNG GAKLTNIFST+F IETADGKR KKYKQVF DNMG KSE
Subjt: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
Query: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
P+ITKCK +NWTKVTFKPDLAKFNMTHLEDDVVALMKKRV+D+AGCLGKTVKVELNGQR+PV+SFQDYVDLYL S STF TEPPKRYH+KPNERWEIVV
Subjt: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
Query: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
LSEGQF QV+FVN IATIKGGTHVDYITNQIANYV+NVVNKKNKNANVKAHNV SY W+F+NALIDNPAFDSQTKETLTIR S+FGSGC+LTPEFLKN
Subjt: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
Query: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
DG +C+ GRDFY VFPLRG +LNVR SS++I
Subjt: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
Query: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
+NKEIQ IKQILGLQ GKEYN+ K LRYGHLMIMTDQDHDGSHIKGLLINFIH FWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKE+LR
Subjt: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
Query: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
GN+SGWSIKYYKGLGTSTSKEGREYF+QL KHKKDFVWQDDHD
Subjt: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
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| XP_022152632.1 DNA topoisomerase 2 isoform X2 [Momordica charantia] | 5.4e-271 | 74.65 | Show/hide |
Query: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
M EKKRP+QNS AN D P G KTIEEMYQKKTQ+EHILLRPDTYVGS+E HTQ LWVYEN KMVHR VTYVPGLYKIF+EILVNAADNKQRDPSMD
Subjt: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
Query: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
SVKV IDVE N ISVFNNGDGVPVE+H EEKVY KKTTGGRNG GAKLTNIFST+F IETADGKR KKYKQVF DNMG KSE
Subjt: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
Query: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
P+ITKCK +NWTKVTFKPDLAKFNMTHLEDDVVALMKKRV+D+AGCLGKTVKVELNGQR+PV+SFQDYVDLYL S STF TEPPKRYH+KPNERWEIVV
Subjt: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
Query: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
LSEGQF QV+FVN IATIKGGTHVDYITNQIANYV+NVVNKKNKNANVKAHNV SY W+F+NALIDNPAFDSQTKETLTIR S+FGSGC+LTPEFLKN
Subjt: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
Query: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
DG +C+ GRDFY VFPLRG +LNVR SS++I
Subjt: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
Query: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
+NKEIQ IKQILGLQ GKEYN+ K LRYGHLMIMTDQDHDGSHIKGLLINFIH FWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKE+LR
Subjt: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
Query: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
GN+SGWSIKYYKGLGTSTSKEGREYF+QL KHKKDFVWQDDHD
Subjt: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
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| XP_023527823.1 DNA topoisomerase 2 isoform X3 [Cucurbita pepo subsp. pepo] | 1.0e-269 | 73.72 | Show/hide |
Query: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
M EKKRP+QNS AAN D PGG KTIEEMYQKKTQ+EHILLRPDTYVGS+E HTQ LW+YEN KMVHR VTYVPGLYKIF+EILVNAADNKQRDPSMD
Subjt: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
Query: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
S+KV ID E N+ISVFNNGDGVPVEVH EEKVY KKTTGGRNG GAKLTNIFST+F IETADG+RLKKYKQVF+DNMG KSE
Subjt: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
Query: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
PIITKCK +NWTKVTFKPDLAKFNMTHLEDDVVALMKKRV+DLAGCLGKTVKVELNGQR+PV+SFQDYVD YL S + F TEPPKRYH++PNERWEIVV
Subjt: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
Query: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
LSEGQF QV+FVNGIATIKGGTHVDYITNQIANYV+ VVNKKNKNANVKAHNV SY W+F+NALIDNPAFDSQTKETLTIR S+FGS C+LTP+FLKN
Subjt: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
Query: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
DG +C+ GRDFY VFPLRG +LNVR SS++I
Subjt: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
Query: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
+NKEIQ IKQILGLQ GKEYN+AK+LRYGHLMIMTDQDHDGSHIKGLLINFIH FWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK+NLR
Subjt: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
Query: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
GN+SGWSIKYYKGLGTSTSKEGREYF+QL KHKKDF+WQD+HD
Subjt: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
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| XP_023527825.1 DNA topoisomerase 2 isoform X5 [Cucurbita pepo subsp. pepo] | 1.0e-269 | 73.72 | Show/hide |
Query: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
M EKKRP+QNS AAN D PGG KTIEEMYQKKTQ+EHILLRPDTYVGS+E HTQ LW+YEN KMVHR VTYVPGLYKIF+EILVNAADNKQRDPSMD
Subjt: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
Query: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
S+KV ID E N+ISVFNNGDGVPVEVH EEKVY KKTTGGRNG GAKLTNIFST+F IETADG+RLKKYKQVF+DNMG KSE
Subjt: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
Query: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
PIITKCK +NWTKVTFKPDLAKFNMTHLEDDVVALMKKRV+DLAGCLGKTVKVELNGQR+PV+SFQDYVD YL S + F TEPPKRYH++PNERWEIVV
Subjt: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
Query: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
LSEGQF QV+FVNGIATIKGGTHVDYITNQIANYV+ VVNKKNKNANVKAHNV SY W+F+NALIDNPAFDSQTKETLTIR S+FGS C+LTP+FLKN
Subjt: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
Query: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
DG +C+ GRDFY VFPLRG +LNVR SS++I
Subjt: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
Query: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
+NKEIQ IKQILGLQ GKEYN+AK+LRYGHLMIMTDQDHDGSHIKGLLINFIH FWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK+NLR
Subjt: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
Query: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
GN+SGWSIKYYKGLGTSTSKEGREYF+QL KHKKDF+WQD+HD
Subjt: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
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| XP_023527826.1 DNA topoisomerase 2 isoform X6 [Cucurbita pepo subsp. pepo] | 1.0e-269 | 73.72 | Show/hide |
Query: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
M EKKRP+QNS AAN D PGG KTIEEMYQKKTQ+EHILLRPDTYVGS+E HTQ LW+YEN KMVHR VTYVPGLYKIF+EILVNAADNKQRDPSMD
Subjt: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
Query: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
S+KV ID E N+ISVFNNGDGVPVEVH EEKVY KKTTGGRNG GAKLTNIFST+F IETADG+RLKKYKQVF+DNMG KSE
Subjt: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
Query: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
PIITKCK +NWTKVTFKPDLAKFNMTHLEDDVVALMKKRV+DLAGCLGKTVKVELNGQR+PV+SFQDYVD YL S + F TEPPKRYH++PNERWEIVV
Subjt: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
Query: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
LSEGQF QV+FVNGIATIKGGTHVDYITNQIANYV+ VVNKKNKNANVKAHNV SY W+F+NALIDNPAFDSQTKETLTIR S+FGS C+LTP+FLKN
Subjt: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
Query: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
DG +C+ GRDFY VFPLRG +LNVR SS++I
Subjt: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
Query: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
+NKEIQ IKQILGLQ GKEYN+AK+LRYGHLMIMTDQDHDGSHIKGLLINFIH FWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK+NLR
Subjt: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
Query: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
GN+SGWSIKYYKGLGTSTSKEGREYF+QL KHKKDF+WQD+HD
Subjt: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
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| TrEMBL top hits | e value | %identity | Alignment |
|---|
| A0A6J1DGT3 DNA topoisomerase 2 | 2.6e-271 | 74.65 | Show/hide |
Query: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
M EKKRP+QNS AN D P G KTIEEMYQKKTQ+EHILLRPDTYVGS+E HTQ LWVYEN KMVHR VTYVPGLYKIF+EILVNAADNKQRDPSMD
Subjt: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
Query: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
SVKV IDVE N ISVFNNGDGVPVE+H EEKVY KKTTGGRNG GAKLTNIFST+F IETADGKR KKYKQVF DNMG KSE
Subjt: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
Query: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
P+ITKCK +NWTKVTFKPDLAKFNMTHLEDDVVALMKKRV+D+AGCLGKTVKVELNGQR+PV+SFQDYVDLYL S STF TEPPKRYH+KPNERWEIVV
Subjt: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
Query: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
LSEGQF QV+FVN IATIKGGTHVDYITNQIANYV+NVVNKKNKNANVKAHNV SY W+F+NALIDNPAFDSQTKETLTIR S+FGSGC+LTPEFLKN
Subjt: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
Query: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
DG +C+ GRDFY VFPLRG +LNVR SS++I
Subjt: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
Query: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
+NKEIQ IKQILGLQ GKEYN+ K LRYGHLMIMTDQDHDGSHIKGLLINFIH FWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKE+LR
Subjt: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
Query: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
GN+SGWSIKYYKGLGTSTSKEGREYF+QL KHKKDFVWQDDHD
Subjt: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
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| A0A6J1DIB5 DNA topoisomerase 2 | 2.6e-271 | 74.65 | Show/hide |
Query: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
M EKKRP+QNS AN D P G KTIEEMYQKKTQ+EHILLRPDTYVGS+E HTQ LWVYEN KMVHR VTYVPGLYKIF+EILVNAADNKQRDPSMD
Subjt: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
Query: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
SVKV IDVE N ISVFNNGDGVPVE+H EEKVY KKTTGGRNG GAKLTNIFST+F IETADGKR KKYKQVF DNMG KSE
Subjt: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
Query: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
P+ITKCK +NWTKVTFKPDLAKFNMTHLEDDVVALMKKRV+D+AGCLGKTVKVELNGQR+PV+SFQDYVDLYL S STF TEPPKRYH+KPNERWEIVV
Subjt: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
Query: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
LSEGQF QV+FVN IATIKGGTHVDYITNQIANYV+NVVNKKNKNANVKAHNV SY W+F+NALIDNPAFDSQTKETLTIR S+FGSGC+LTPEFLKN
Subjt: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
Query: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
DG +C+ GRDFY VFPLRG +LNVR SS++I
Subjt: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
Query: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
+NKEIQ IKQILGLQ GKEYN+ K LRYGHLMIMTDQDHDGSHIKGLLINFIH FWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKE+LR
Subjt: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
Query: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
GN+SGWSIKYYKGLGTSTSKEGREYF+QL KHKKDFVWQDDHD
Subjt: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
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| A0A6J1F3D6 DNA topoisomerase 2 | 1.9e-269 | 73.72 | Show/hide |
Query: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
M EKKRP+QNS AAN D P G KTIEEMYQKKTQ+EHILLRPDTYVGS+E HTQ LWVYEN KMVHR VTYVPGLYKIF+EILVNAADNKQRDPSMD
Subjt: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
Query: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
S+KV ID E N+ISVFNNGDGVPVEVH EEKVY KKTTGGRNG GAKLTNIFST+F IETADG+RLKKYKQVF+DNMG KSE
Subjt: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
Query: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
PIITKCK +NWTKVTFKPDLAKFNMTHLEDDVVALMKKRV+DLAGCLGKTVKVELNGQR+PV+SFQDYVD YL S + F TEPPKRYH++PNERWEIVV
Subjt: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
Query: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
LSEGQF QV+FVNGIATIKGGTHVDYITNQIANYV+ VVNKKNKNANVKAHNV SY W+F+NALIDNPAFDSQTKETLTIR S+FGS C+LTP+FLKN
Subjt: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
Query: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
DG +C+ GRDFY VFPLRG +LNVR SS++I
Subjt: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
Query: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
+NKEIQ IKQILGLQ GKEYN+AK+LRYGHLMIMTDQDHDGSHIKGLLINFIH FWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK+NLR
Subjt: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
Query: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
GN+SGWSIKYYKGLGTSTSKEGREYF+QL KHKKDF+WQD+HD
Subjt: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
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| A0A6J1F9E0 DNA topoisomerase 2 | 1.9e-269 | 73.72 | Show/hide |
Query: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
M EKKRP+QNS AAN D P G KTIEEMYQKKTQ+EHILLRPDTYVGS+E HTQ LWVYEN KMVHR VTYVPGLYKIF+EILVNAADNKQRDPSMD
Subjt: MPAEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
Query: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
S+KV ID E N+ISVFNNGDGVPVEVH EEKVY KKTTGGRNG GAKLTNIFST+F IETADG+RLKKYKQVF+DNMG KSE
Subjt: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
Query: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
PIITKCK +NWTKVTFKPDLAKFNMTHLEDDVVALMKKRV+DLAGCLGKTVKVELNGQR+PV+SFQDYVD YL S + F TEPPKRYH++PNERWEIVV
Subjt: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVV
Query: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
LSEGQF QV+FVNGIATIKGGTHVDYITNQIANYV+ VVNKKNKNANVKAHNV SY W+F+NALIDNPAFDSQTKETLTIR S+FGS C+LTP+FLKN
Subjt: ALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-
Query: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
DG +C+ GRDFY VFPLRG +LNVR SS++I
Subjt: -------------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIA
Query: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
+NKEIQ IKQILGLQ GKEYN+AK+LRYGHLMIMTDQDHDGSHIKGLLINFIH FWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK+NLR
Subjt: KNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLR
Query: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
GN+SGWSIKYYKGLGTSTSKEGREYF+QL KHKKDF+WQD+HD
Subjt: GNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
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| A0A6J1J555 DNA topoisomerase 2 | 7.9e-268 | 73.48 | Show/hide |
Query: AEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMDSV
A +KRP+QNS AAN D P G KTIEEMYQKKTQ+EHILLRPDTYVGS+E HTQ LW+YEN KMVHR VTYVPGLYKIF+EILVNAADNKQRDPSMDS+
Subjt: AEKKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMDSV
Query: KVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSEPI
KV ID E N ISVFNNGDGVPVEVH EEKVY KKTTGGRNG GAKLTNIFST+F IETADG+RLKKYKQVF+DNMG KSEPI
Subjt: KVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSEPI
Query: ITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVVAL
ITKCK +NWTKVTFKPDLAKFNMTHLEDDVVALMKKRV+DLAGCLGKTVKVELNGQR+PV+SFQDYVD YL S + F TEPPKRYH++PNERWEIVV L
Subjt: ITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVVAL
Query: SEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN---
SEGQF QV+FVNGIATIKGGTHVDYITNQIANYV+ VVNKKNKNANVKAHNV SY W+F+NALIDNPAFDSQTKETLTIR S+FGS C+LTP+FLKN
Subjt: SEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN---
Query: -----------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIAKN
DG +C+ GRDFY VFPLRG +LNVR SS++I +N
Subjt: -----------------------DG----------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIAKN
Query: KEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLRGN
KEIQ IKQILGLQ GKEYN+AK+LRYGHLMIMTDQDHDGSHIKGLLINFIH FWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK+NLRGN
Subjt: KEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLRGN
Query: SSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
+SGWSIKYYKGLGTSTSKEGREYF+QL KHKKDF+WQD+HD
Subjt: SSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
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| SwissProt top hits | e value | %identity | Alignment |
|---|
| O24308 DNA topoisomerase 2 | 1.3e-222 | 61.85 | Show/hide |
Query: KKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMDSVKV
+KRP+Q S AAN IP +KTIEEMYQKKTQ+EHILLRPDTYVGS+E HTQ LWVYEN +MVHR V+YVPGLYKIF+EILVNAADNKQRDPSMDS+KV
Subjt: KKRPMQNSAAANGDPIPGGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMDSVKV
Query: EIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSEPIIT
ID E N +SV+NNGDGVPVE+H EEKVY KKTTGGRNG GAKLTNIFST+F IETADG+RLKKYKQVF++NMG+K EP+IT
Subjt: EIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSEPIIT
Query: KCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVVALSE
KCKA+ENWTKVTFKPDL KF M +LE+DVVALMKKRV+D+AGC GKTVKVELNG I +SF+DY DL+L P R H K +RWEI ++LS+
Subjt: KCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVVALSE
Query: GQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-----
GQF QV+FVN IATIKGGTHVDYITNQI Y++N VNKK K+ANVKAH V ++ W+FVN+LIDNPAFDSQTKETLT R ++FGS CD+ LK+
Subjt: GQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN-----
Query: --------------------DG---------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIAKNKEIQ
DG +C+ GRD Y VFPLRG +LNVR SS++I N+EIQ
Subjt: --------------------DG---------------------RTRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIAKNKEIQ
Query: EIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLRGNSSGW
IK+ILGLQ KEY + KSLRYGHLMIM DQDHDGSHIKGLLINFIH FWPSLL+VPSFLVEF TP+++A+H N T+ SFY+MPEYE+WKE L +++ W
Subjt: EIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLRGNSSGW
Query: SIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
IKYYKGLGTST +EGREYF L +H+KDF+W D+ D
Subjt: SIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
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| O46374 DNA topoisomerase 2-alpha | 6.4e-150 | 48.87 | Show/hide |
Query: TIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVY-ENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMDSVKVEIDVEGNWISVFNNGDGVPVE
+IE +YQKKTQ+EHILLRPDTY+GSVE+ TQ +WVY E+ + +R VT+VPGLYKIF+EILVNAADNKQRDP M ++V ID E N IS++NNG G+PV
Subjt: TIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVY-ENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMDSVKVEIDVEGNWISVFNNGDGVPVE
Query: VHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSEPIITKCKATENWTKVTFKPDLAKFN
H EK+Y KK TGGRNG GAKL NIFST+F +ETA + K +KQ + DNMG E + E++T +TF PDL+KF
Subjt: VHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSEPIITKCKATENWTKVTFKPDLAKFN
Query: MTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVVALSEGQFHQVTFVNGIATIKGGTHV
M L+ D+VALM +R D+AG K VKV LNG ++PV+ F+ YVDLYL P K H + N RWE+ + +SE F Q++FVN IAT KGG HV
Subjt: MTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVVALSEGQFHQVTFVNGIATIKGGTHV
Query: DYITNQIANYVVNVVNKKNK-NANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLK--------------------------
DY+ +QI +V+VV KKNK VKAH V ++ WIFVNALI+NP FDSQTKE +T++ +FGS C L+ +F+K
Subjt: DYITNQIANYVVNVVNKKNK-NANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLK--------------------------
Query: ------------------ND--GR--TRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIAKNKEIQEIKQILGLQHGKEYND--
ND GR T C+ GRD Y VFPLRG ILNVR S ++I +N EI I +I+GLQ+ K Y D
Subjt: ------------------ND--GR--TRCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIAKNKEIQEIKQILGLQHGKEYND--
Query: -AKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLRGNSSGWSIKYYKGLGTSTSKE
K+LRYG +MIMTDQD DGSHIKGLLINFIH+ WPSLLR FL EFITPIVK + +N ++FY++PE+E WK + N W +KYYKGLGTSTSKE
Subjt: -AKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLRGNSSGWSIKYYKGLGTSTSKE
Query: GREYFKQLEKHKKDFVWQDDHD
+EYF +++H+ F + D
Subjt: GREYFKQLEKHKKDFVWQDDHD
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| P08096 DNA topoisomerase 2 | 6.6e-163 | 47.99 | Show/hide |
Query: GGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVY--ENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMDSVKVEIDVEGNWISVFNNG
G N + YQ+ T EH+L RPDTY+GS+E T +WV+ E K+ ++ VTYVPGLYKIF+EI+VNAADNK RDP+M+++KV +D E N IS++NNG
Subjt: GGSNKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVY--ENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMDSVKVEIDVEGNWISVFNNG
Query: DGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSEPIITKCKATENWTKVTFKP
G+P+E+H +EK+Y KK TGGRNG GAKL NIFST+F +ETAD +R+KKYKQ + DNM KSEP+IT K + +TK+TFKP
Subjt: DGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSEPIITKCKATENWTKVTFKP
Query: DLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVVALSEGQFHQVTFVNGIATI
DLAKF M ++DD+V+++K+R+ D+AG + +T KV LN +RI + F+ YV++YL S + EPP+ + N+RW++ A+S+GQF QV+FVN I+TI
Subjt: DLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPPKRYHVKPNERWEIVVALSEGQFHQVTFVNGIATI
Query: KGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFL----------------------
+GGTHV+Y+ N+I + + VV K+NK A VKA + +Y +FVN I+NP+FDSQTKETLT + S FGS C L+ +FL
Subjt: KGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFL----------------------
Query: ---KNDG--RTRCS----------------------------------------GRDFYSVFPLRGVILNVRVKSSEEIAKNKEIQEIKQILGLQHGKEY
K DG R+R + GRD+Y VFPLRG +LNVR S +I NKEIQ IK+I+G H K Y
Subjt: ---KNDG--RTRCS----------------------------------------GRDFYSVFPLRGVILNVRVKSSEEIAKNKEIQEIKQILGLQHGKEY
Query: NDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLRGNSSGWSIKYYKGLGTSTSK
D K LRYGHLMIMTDQDHDGSHIKGL+IN++ +PSLL++P FL++FITPI+K T R V +FYT+PEYE WKE N GW IKYYKGLGTS
Subjt: NDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLRGNSSGWSIKYYKGLGTSTSK
Query: EGREYFKQLEKHKKDFVWQDDHD
+ + YF L++H K F + D
Subjt: EGREYFKQLEKHKKDFVWQDDHD
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| P30182 DNA topoisomerase 2 | 4.1e-221 | 62.27 | Show/hide |
Query: KRPMQNSAAANGDPIPGGS-----NKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
K P+QNS AAN P S KTIEEMYQKK+Q+EHILLRPDTY+GS+E HTQTLWVYE +MV R VTYVPGLYKIF+EILVNAADNKQRD MD
Subjt: KRPMQNSAAANGDPIPGGS-----NKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
Query: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
SV+V IDVE N ISV N+G GVPVE+H EE +Y KKTTGGRNG GAKLTNIFST+F IETADGKRLKKYKQVF +NMG KSE
Subjt: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
Query: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPP-KRYHVKPNERWEIV
P+ITKC +ENWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG++IPV+SF DYVDLYL++ + TE P R K N+RWE+
Subjt: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPP-KRYHVKPNERWEIV
Query: VALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN
V+LSEGQF QV+FVN IATIKGGTHVDY+T+QI N++V VNKKNKNANVKAHNV ++ W+FVNALIDNPAFDSQTKETLT+R S+FGS C+L+ +FLK
Subjt: VALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN
Query: DGRT----------------------------------------------RCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIAK
G++ C+ G ++ VFPLRG +LNVR S+ +I
Subjt: DGRT----------------------------------------------RCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIAK
Query: NKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKENL
NKEI+ +K+ILGL+ +Y + SLRYG +MIMTDQDHDGSHIKGLLINFIH FWPSLL+VPSFLVEFITPIVKAT R GT VLSFY+MPEYE WKE+L
Subjt: NKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKENL
Query: RGNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
+GN++GW IKYYKGLGTST++EG+EYF L HKKDFVW+D+ D
Subjt: RGNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
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| Q55BP5 Probable DNA topoisomerase 2 | 9.6e-154 | 47.5 | Show/hide |
Query: KTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMDSVKVEIDVEGNWISVFNNGDGVPVE
K+IEE+YQKK ++ ILLRPDTY+GS E + LWV+E+ +MVHR V++VPG+YKIF+EILVNAADNKQR+ +M +KV ID E +ISV N+G G+P++
Subjt: KTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMDSVKVEIDVEGNWISVFNNGDGVPVE
Query: VHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSEPIITKCKATENWTKVTFKPDLAKFN
VH E K+Y K+ TGGRNG GAKL NIFST+F +E AD K K YKQ F +NM SK +P IT + ++TK+TF P+L +F
Subjt: VHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSEPIITKCKATENWTKVTFKPDLAKFN
Query: MTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTE--PPKRYHVKPNERWEIVVALS-EGQFHQVTFVNGIATIKGG
M +DD+VAL+ KRV D+AGC T+KV LN + + +RSF+ Y++LY FP E PK Y+ K ++RWE+ V LS E QF+QV+FVN I T+KGG
Subjt: MTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTE--PPKRYHVKPNERWEIVVALS-EGQFHQVTFVNGIATIKGG
Query: THVDYITNQIANYVVNVVNKKNK-NANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN----------------------
THV + + I + VNKKNK +A++K + ++ +FVN LI+NP FDSQTKETLT + S+FGS C+ + +F+K
Subjt: THVDYITNQIANYVVNVVNKKNK-NANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN----------------------
Query: -------------------------DGRTR---CS--------------------GRDFYSVFPLRGVILNVRVKSSEEIAKNKEIQEIKQILGLQHGKE
G T+ C+ G+D Y FPL+G +LNVR +S+ ++ N EI I ILGL++GK
Subjt: -------------------------DGRTR---CS--------------------GRDFYSVFPLRGVILNVRVKSSEEIAKNKEIQEIKQILGLQHGKE
Query: YNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLRGNSSGWSIKYYKGLGTSTS
Y LRYGHLMIMTDQDHDGSHIKGL+IN +H+FWP+LLR+P FLVEFITPIVK N +SFYTMPE+ W+E N GW +KYYKGLGTST
Subjt: YNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLRGNSSGWSIKYYKGLGTSTS
Query: KEGREYFKQLEKHKKDFVWQD
EG+EYF LE+HK DF W +
Subjt: KEGREYFKQLEKHKKDFVWQD
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| Arabidopsis top hits | e value | %identity | Alignment |
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| AT3G10270.1 DNA GYRASE B1 | 3.2e-11 | 33.56 | Show/hide |
Query: GRTRCSGRD--FYSVFPLRGVILNVRVKSSEEIAKNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFL
G + GRD F ++ PLRG ILN+ K + KN+EIQ + LGL E + ++LRY ++I+TD D DG+HI+ LL+ F + +L
Subjt: GRTRCSGRD--FYSVFPLRGVILNVRVKSSEEIAKNKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFL
Query: VEFITPIVKATHRNGTVLSFYTMPEYESWKENLRGNSSGWSIKYYKGLG
V + P+ K R Y + + GN+S ++I+ +KGLG
Subjt: VEFITPIVKATHRNGTVLSFYTMPEYESWKENLRGNSSGWSIKYYKGLG
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| AT3G23890.1 topoisomerase II | 2.9e-222 | 62.27 | Show/hide |
Query: KRPMQNSAAANGDPIPGGS-----NKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
K P+QNS AAN P S KTIEEMYQKK+Q+EHILLRPDTY+GS+E HTQTLWVYE +MV R VTYVPGLYKIF+EILVNAADNKQRD MD
Subjt: KRPMQNSAAANGDPIPGGS-----NKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
Query: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
SV+V IDVE N ISV N+G GVPVE+H EE +Y KKTTGGRNG GAKLTNIFST+F IETADGKRLKKYKQVF +NMG KSE
Subjt: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
Query: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPP-KRYHVKPNERWEIV
P+ITKC +ENWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG++IPV+SF DYVDLYL++ + TE P R K N+RWE+
Subjt: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPP-KRYHVKPNERWEIV
Query: VALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN
V+LSEGQF QV+FVN IATIKGGTHVDY+T+QI N++V VNKKNKNANVKAHNV ++ W+FVNALIDNPAFDSQTKETLT+R S+FGS C+L+ +FLK
Subjt: VALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN
Query: DGRT----------------------------------------------RCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIAK
G++ C+ G ++ VFPLRG +LNVR S+ +I
Subjt: DGRT----------------------------------------------RCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIAK
Query: NKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKENL
NKEI+ +K+ILGL+ +Y + SLRYG +MIMTDQDHDGSHIKGLLINFIH FWPSLL+VPSFLVEFITPIVKAT R GT VLSFY+MPEYE WKE+L
Subjt: NKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKENL
Query: RGNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
+GN++GW IKYYKGLGTST++EG+EYF L HKKDFVW+D+ D
Subjt: RGNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
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| AT3G23890.2 topoisomerase II | 2.9e-222 | 62.27 | Show/hide |
Query: KRPMQNSAAANGDPIPGGS-----NKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
K P+QNS AAN P S KTIEEMYQKK+Q+EHILLRPDTY+GS+E HTQTLWVYE +MV R VTYVPGLYKIF+EILVNAADNKQRD MD
Subjt: KRPMQNSAAANGDPIPGGS-----NKTIEEMYQKKTQVEHILLRPDTYVGSVENHTQTLWVYENGKMVHRCVTYVPGLYKIFNEILVNAADNKQRDPSMD
Query: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
SV+V IDVE N ISV N+G GVPVE+H EE +Y KKTTGGRNG GAKLTNIFST+F IETADGKRLKKYKQVF +NMG KSE
Subjt: SVKVEIDVEGNWISVFNNGDGVPVEVHLEEKVY-------------------KKTTGGRNGLGAKLTNIFSTQFFIETADGKRLKKYKQVFNDNMGSKSE
Query: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPP-KRYHVKPNERWEIV
P+ITKC +ENWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG++IPV+SF DYVDLYL++ + TE P R K N+RWE+
Subjt: PIITKCKATENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRIPVRSFQDYVDLYLNSVSTFPTEPP-KRYHVKPNERWEIV
Query: VALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN
V+LSEGQF QV+FVN IATIKGGTHVDY+T+QI N++V VNKKNKNANVKAHNV ++ W+FVNALIDNPAFDSQTKETLT+R S+FGS C+L+ +FLK
Subjt: VALSEGQFHQVTFVNGIATIKGGTHVDYITNQIANYVVNVVNKKNKNANVKAHNVNSYFWIFVNALIDNPAFDSQTKETLTIRHSNFGSGCDLTPEFLKN
Query: DGRT----------------------------------------------RCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIAK
G++ C+ G ++ VFPLRG +LNVR S+ +I
Subjt: DGRT----------------------------------------------RCS--------------------GRDFYSVFPLRGVILNVRVKSSEEIAK
Query: NKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKENL
NKEI+ +K+ILGL+ +Y + SLRYG +MIMTDQDHDGSHIKGLLINFIH FWPSLL+VPSFLVEFITPIVKAT R GT VLSFY+MPEYE WKE+L
Subjt: NKEIQEIKQILGLQHGKEYNDAKSLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKENL
Query: RGNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
+GN++GW IKYYKGLGTST++EG+EYF L HKKDFVW+D+ D
Subjt: RGNSSGWSIKYYKGLGTSTSKEGREYFKQLEKHKKDFVWQDDHD
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| AT5G04130.1 DNA GYRASE B2 | 3.8e-12 | 35.1 | Show/hide |
Query: GRTRCSGRD--FYSVFPLRGVILNVRVKSSEEIAKNKEIQEIKQILGLQHGKEYNDAK--SLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPS
G + GRD F ++ PLRG ILN+ K + KN+EIQ + ILGL G + D K +LRY ++I+TD D DG+HI+ LL+ F + +L
Subjt: GRTRCSGRD--FYSVFPLRGVILNVRVKSSEEIAKNKEIQEIKQILGLQHGKEYNDAK--SLRYGHLMIMTDQDHDGSHIKGLLINFIHYFWPSLLRVPS
Query: FLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLRGNSSGWSIKYYKGLG
V + P+ K R Y + + N N+S ++I+ +KGLG
Subjt: FLVEFITPIVKATHRNGTVLSFYTMPEYESWKENLRGNSSGWSIKYYKGLG
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