CuGenDBv2

Gene ID	Sed0007168
Organism	Sechium edule (Chayote v1)
Description	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Genome location	LG07:12928056..12940074
RNA-Seq Expression	Sed0007168
Synteny	Sed0007168
Gene Ontology terms	GO:0015995 - chlorophyll biosynthetic process (biological process) GO:0016117 - carotenoid biosynthetic process (biological process) GO:0019288 - isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (biological process) GO:0008685 - 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity (molecular function) GO:0046872 - metal ion binding (molecular function)
InterPro domains	IPR003526 - 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IPR036571 - 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily

Homology

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GenBank top hits

e value

%identity

Alignment

EOY24852.1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [Theobroma cacao]

1.8e-44

86.49

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Query:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI
        ++ ALGLPDIGQIFPDSDPK  GAPSSVF KE VRLMHEVGY+IGNLDATLILQRPKLSPHKEA I+A+LSELLGADP VVNLKAKTHEKV SLG+NRSI
Subjt:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI

Query:  AAHTVVLLMRR
        AAHTVVLLMR+
Subjt:  AAHTVVLLMRR

KAA0044847.1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [Cucumis melo var. makuwa]

3.6e-45

88.29

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Query:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI
        ++ ALGLPDIGQIFPDSDPK  GAPSSVF KE VRLMHE GYDIGNLDATLILQRPKLSPHKEA IRA+LSELLGADP VVNLKAKTHEKV SLG+NRSI
Subjt:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI

Query:  AAHTVVLLMRR
        AAHTVVLLMRR
Subjt:  AAHTVVLLMRR

PON97772.1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site [Trema orientale]

1.4e-44

86.49

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Query:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI
        ++ ALGLPDIGQIFPDSDPK  GAPSSVF KE VRLMHE GYD+GNLDATLILQRPKLSPHKEA IRA+LSELLGADP VVNLKAKTHEKV SLG+NRSI
Subjt:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI

Query:  AAHTVVLLMRR
        AAHTVVLLMR+
Subjt:  AAHTVVLLMRR

XP_008452007.1 PREDICTED: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, chloroplastic [Cucumis melo]

3.6e-45

88.29

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Query:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI
        ++ ALGLPDIGQIFPDSDPK  GAPSSVF KE VRLMHE GYDIGNLDATLILQRPKLSPHKEA IRA+LSELLGADP VVNLKAKTHEKV SLG+NRSI
Subjt:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI

Query:  AAHTVVLLMRR
        AAHTVVLLMRR
Subjt:  AAHTVVLLMRR

XP_017973969.1 PREDICTED: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, chloroplastic [Theobroma cacao]

1.8e-44

86.49

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Query:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI
        ++ ALGLPDIGQIFPDSDPK  GAPSSVF KE VRLMHEVGY+IGNLDATLILQRPKLSPHKEA I+A+LSELLGADP VVNLKAKTHEKV SLG+NRSI
Subjt:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI

Query:  AAHTVVLLMRR
        AAHTVVLLMR+
Subjt:  AAHTVVLLMRR

TrEMBL top hits

e value

%identity

Alignment

A0A061G6M7 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

8.7e-45

86.49

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Query:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI
        ++ ALGLPDIGQIFPDSDPK  GAPSSVF KE VRLMHEVGY+IGNLDATLILQRPKLSPHKEA I+A+LSELLGADP VVNLKAKTHEKV SLG+NRSI
Subjt:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI

Query:  AAHTVVLLMRR
        AAHTVVLLMR+
Subjt:  AAHTVVLLMRR

A0A1S3BTZ8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

1.8e-45

88.29

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Query:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI
        ++ ALGLPDIGQIFPDSDPK  GAPSSVF KE VRLMHE GYDIGNLDATLILQRPKLSPHKEA IRA+LSELLGADP VVNLKAKTHEKV SLG+NRSI
Subjt:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI

Query:  AAHTVVLLMRR
        AAHTVVLLMRR
Subjt:  AAHTVVLLMRR

A0A2P5FJ12 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

6.7e-45

86.49

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Query:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI
        ++ ALGLPDIGQIFPDSDPK  GAPSSVF KE VRLMHE GYD+GNLDATLILQRPKLSPHKEA IRA+LSELLGADP VVNLKAKTHEKV SLG+NRSI
Subjt:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI

Query:  AAHTVVLLMRR
        AAHTVVLLMR+
Subjt:  AAHTVVLLMRR

A0A5A7TSJ1 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

1.8e-45

88.29

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Query:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI
        ++ ALGLPDIGQIFPDSDPK  GAPSSVF KE VRLMHE GYDIGNLDATLILQRPKLSPHKEA IRA+LSELLGADP VVNLKAKTHEKV SLG+NRSI
Subjt:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI

Query:  AAHTVVLLMRR
        AAHTVVLLMRR
Subjt:  AAHTVVLLMRR

A0A5D3D287 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

1.8e-45

88.29

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Query:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI
        ++ ALGLPDIGQIFPDSDPK  GAPSSVF KE VRLMHE GYDIGNLDATLILQRPKLSPHKEA IRA+LSELLGADP VVNLKAKTHEKV SLG+NRSI
Subjt:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI

Query:  AAHTVVLLMRR
        AAHTVVLLMRR
Subjt:  AAHTVVLLMRR

SwissProt top hits

e value

%identity

Alignment

B2UFT6 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

1.1e-23

51.82

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Query:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI
        L  A GL DIG+ FPD+DP   GA S V  +E VR +H+ GY +GN+DAT+I Q+PKL+PH   M+ A+L+E LG  P   N+KAKT+EK+G  GK   I
Subjt:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI

Query:  AAHTVVLLMR
         A  VVL+ R
Subjt:  AAHTVVLLMR

B8GQ78 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

6.9e-23

50.93

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Query:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI
        L+ A  L DIG+ FPD+DP   GA S V  + VV L+HE GY +GN+DAT+I Q PK++PH EAM RA+L++ LG     VN+KA T E++G  G+   I
Subjt:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI

Query:  AAHTVVLL
        AAH V L+
Subjt:  AAHTVVLL

Q6EPN6 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, chloroplastic

1.1e-41

75.68

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Query:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI
        ++ ALGLPDIGQIFPDSDP+  GA SSVF +E V+LMHE GY++GNLDATLILQ+PK+SP KE  IR++L +LLGADP VVNLKAKTHEKV SLG+NRSI
Subjt:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI

Query:  AAHTVVLLMRR
        AAHTVVLLMR+
Subjt:  AAHTVVLLMRR

Q9CAK8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, chloroplastic

2.7e-43

79.28

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Query:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI
        ++ ALGLPDIGQIFPDSDPK  GA SSVF KE VRLM E GY+IGNLDATLILQRPK+SPHKE  IR++LS+LLGADP VVNLKAKTHEKV SLG+NRSI
Subjt:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI

Query:  AAHTVVLLMRR
        AAHTV+LLM++
Subjt:  AAHTVVLLMRR

Q9M4W3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, chloroplastic

1.6e-43

80.18

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Query:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI
        ++ ALGLPDIGQIFPD+DPK  GAPSSVF KE VRLM E GY++GNLDATLILQRPK+SPHKEA IR +L +LLGADP VVNLKAKTHEKV SLG+NRSI
Subjt:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI

Query:  AAHTVVLLMRR
        AAHTVVLLMR+
Subjt:  AAHTVVLLMRR

Arabidopsis top hits

e value

%identity

Alignment

AT1G63970.1 isoprenoid F

1.9e-44

79.28

Show/hide

Query:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI
        ++ ALGLPDIGQIFPDSDPK  GA SSVF KE VRLM E GY+IGNLDATLILQRPK+SPHKE  IR++LS+LLGADP VVNLKAKTHEKV SLG+NRSI
Subjt:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI

Query:  AAHTVVLLMRR
        AAHTV+LLM++
Subjt:  AAHTVVLLMRR

AT1G63970.2 isoprenoid F

1.9e-44

79.28

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Query:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI
        ++ ALGLPDIGQIFPDSDPK  GA SSVF KE VRLM E GY+IGNLDATLILQRPK+SPHKE  IR++LS+LLGADP VVNLKAKTHEKV SLG+NRSI
Subjt:  LMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVGSLGKNRSI

Query:  AAHTVVLLMRR
        AAHTV+LLM++
Subjt:  AAHTVVLLMRR

Sequences

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CDS sequence

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ATGACAGAGGCTGCTAGGCTCATTTTGATGGAGATGTTTTACTTCACTGTGTGGTTGATGGATGCTTTGGGGCTTCCTGATATTGGACAAATCTTTCCAGATTCAGATCC
CAAATGCATGGGTGCTCCATCATCTGTTTTCACTAAAGAAGTTGTGAGACTGATGCATGAGGTAGGTTATGACATAGGAAACTTGGATGCCACATTAATACTCCAAAGAC
CAAAGCTTAGCCCTCACAAAGAAGCTATGATCAGAGCACACCTCTCCGAGCTTCTGGGAGCGGACCCACCTGTCGTGAATCTGAAGGCGAAAACACACGAGAAGGTCGGC
AGCCTCGGCAAAAACCGAAGCATTGCTGCCCATACTGTGGTCCTCCTAATGAGGAGATAG

mRNA sequence

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AAAAAGGTATGAACTATGCTAACCCTTGCTTGGTATGGAAAATTTAGGAAAACATTATTGTCGTGGGGAACTTATCCTCCATGTAAGGAAATGACAAAAAGTTGGGATTT
TTCAGCATGTGAGTATTGTAAGTGGTCCTACACAACAGCCGCCGTCGCCACAGCCGCCTTTCCATGACTGTCTCCGCCCCCCTCTTCGCTTCTCCGGCCACTACTGCAAC
CACCAGCCATTCCCTTTCTCTTTCCCTCAACCCCCGTTCCTTTCTCACAATAAATTTCAATCTTGTTTCATTCTCCCTCTACGGACGCCACCGCCGCCGTCCACTCTGAT
CGGGCCGCCGCCACCATTTCCCGGTCCAAAGCCTTGCCGTTTCGGGTCGGGAATGGGTTCGATCTCCATAGGTTGAAGCCGAGTTATCCTTTAATTATTGGGGGGATTAC
TTTTCCTCATGACAGAGGCTGCTAGGCTCATTTTGATGGAGATGTTTTACTTCACTGTGTGGTTGATGGATGCTTTGGGGCTTCCTGATATTGGACAAATCTTTCCAGAT
TCAGATCCCAAATGCATGGGTGCTCCATCATCTGTTTTCACTAAAGAAGTTGTGAGACTGATGCATGAGGTAGGTTATGACATAGGAAACTTGGATGCCACATTAATACT
CCAAAGACCAAAGCTTAGCCCTCACAAAGAAGCTATGATCAGAGCACACCTCTCCGAGCTTCTGGGAGCGGACCCACCTGTCGTGAATCTGAAGGCGAAAACACACGAGA
AGGTCGGCAGCCTCGGCAAAAACCGAAGCATTGCTGCCCATACTGTGGTCCTCCTAATGAGGAGATAGAAAGGCATCCCATCCCATCCCATAACTGGCTGCAGTGCCACA
TTATTCCCATCCACAGTTTCTTACAGACTGTTGTAAGTTGGTTGATGAATTAAACGTTTTAATCATTCAACAACATTAAAATGAAAGTGGTATGATATGGTGGAACAATA
TTAGAAATTTCCTACAATCATTGCTTTTATTTTTCGCATTTTTCTTCTTCCTTTTGAATTTGAGTTGGGTTAGCTTTAATGGTCG

Protein sequence

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MTEAARLILMEMFYFTVWLMDALGLPDIGQIFPDSDPKCMGAPSSVFTKEVVRLMHEVGYDIGNLDATLILQRPKLSPHKEAMIRAHLSELLGADPPVVNLKAKTHEKVG
SLGKNRSIAAHTVVLLMRR

Sed0007168 (gene) of Chayote v1 genome