CuGenDBv2

Gene ID	Sed0010212
Organism	Sechium edule (Chayote v1)
Description	DNA topoisomerase
Genome location	LG02:38984177..39038921
RNA-Seq Expression	Sed0010212
Synteny	Sed0010212
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0005634 - nucleus (cellular component) GO:0005694 - chromosome (cellular component) GO:0003677 - DNA binding (molecular function) GO:0008270 - zinc ion binding (molecular function) GO:0003917 - DNA topoisomerase type I activity (molecular function)
InterPro domains	IPR003602 - DNA topoisomerase, type IA, DNA-binding domain IPR034144 - DNA topoisomerase 3-like, TOPRIM domain IPR023406 - DNA topoisomerase, type IA, active site IPR023405 - DNA topoisomerase, type IA, core domain IPR013826 - DNA topoisomerase, type IA, central region, subdomain 3 IPR013825 - DNA topoisomerase, type IA, central region, subdomain 2 IPR013824 - DNA topoisomerase, type IA, central region, subdomain 1 IPR013497 - DNA topoisomerase, type IA, central IPR010666 - Zinc finger, GRF-type IPR006171 - TOPRIM domain IPR003601 - DNA topoisomerase, type IA, domain 2 IPR001878 - Zinc finger, CCHC-type IPR000380 - DNA topoisomerase, type IA

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

XP_022154286.1 DNA topoisomerase 3-alpha [Momordica charantia]

0.0e+00

90.58

Show/hide

Query:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK
        MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVR+GRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEF+ERYRKWHSCDPA+LF APV K VPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVV+VCTAVNRHL IKRAHFSALIERDIHEA QNLVQPN+WFADAVDARQEIDLRIGASFTRFQTMLL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY
        KDAF IDSVTDDKN++LSYGPCQFPTLGFVVERYW+IQSHEPEEFWTINCSHNSDDG+STFSWTRG+LFDYTCAV+LYEMCVQESTATV+NVRRQETLKY
Subjt:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLH IVQEQQ HQIWGAYAQRLLDPGSGLWRNPS GGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHH+LYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKD NTRF+PTNLGEALVMGYDDMGYKLWKP+LRA+MEHEMKAV EGTKRK EVLA  LQQMKTC
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC

Query:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ
        FLDARLNKLKL EAMEVFFERSNGSGGDE+H VG VVRRCGLCQDSDM LKRNR             CRNV+WLPGS+AEAAVT +CCNSCTPGPVYLIQ
Subjt:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ

Query:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRG-TSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSN
        FKFR LEIPPNY+AN+LGCIGGCDDILRQLTEICGTGSR+S RGRG TSSSS QRGNTG+ VC  CQQVGH+SN CPSQ VGSRSAR RQSGESSVSCSN
Subjt:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRG-TSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSN

Query:  CSTPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNSA-RSNIRSSGSASSNPNPGRSTGRERGRGRGQIAATFVSATGEPISDRRCFVCGD
        C TPCVLRTANTANNRGRKFY C SQ+CNFFVWED++ +GNGGNSA RSNIR S S +SNPNPG++TG  RGRGRG IA TFVSATGEPISDRRCFVCGD
Subjt:  CSTPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNSA-RSNIRSSGSASSNPNPGRSTGRERGRGRGQIAATFVSATGEPISDRRCFVCGD

Query:  PSHFANVCPNRGA
        PSHFANVCPNRGA
Subjt:  PSHFANVCPNRGA

XP_022934066.1 DNA topoisomerase 3-alpha isoform X1 [Cucurbita moschata]

0.0e+00

90.72

Show/hide

Query:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK
        M+GGRPITVLNVAEKPSVAK+VATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEF+ERYRKWHSCDP ELF APV K VPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        MDIKRTLEQEA RCQWLVLWLDCDREGENIAFEVVEVCT VNRHLNIKRAHFSALIERDIHEA QNLVQPNK++ADAVDARQEIDLRIGASFTRFQTMLL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY
        KDAFNIDSV DD+N+VLSYGPCQFPTLGFVVERYW+IQSHEPEEFWTINCSHNS DG+STFSWTRGNLFDYTCAV+LYEMCV+ESTATV+NV+RQETLKY
Subjt:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETD FSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTY SGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRF+PTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAV EG KRKDEVLATCLQQMK+C
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC

Query:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ
        FLDAR NK KLFEAMEVFFERSNGSGGDENHAVGEVV+RC LCQDSDM LKRNR             CRNV+WLPGS+AEAAVTSN CNSCTPGPVYLIQ
Subjt:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ

Query:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNC
        FKFRQLEIPPNY+ N+LGCIGGCDDILRQLTEICGTGSR+SARGRGTSSSS+QRGNT +SVC FCQQ+ H+SN CPSQ VGSRSAR RQ+GESS SCSNC
Subjt:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNC

Query:  STPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNS-ARSNIRSSGSASSNPNPGRSTGRERGR----GRGQIAATFVSATGEPISDRRCFV
         TPCVLRTANT NNRGRKFYKC SQECNFF WED + + NGGNS ARSNIRSSGSA+SN NPGR+TGR RGR    G+GQIAATFVSA GEPISDRRCFV
Subjt:  STPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNS-ARSNIRSSGSASSNPNPGRSTGRERGR----GRGQIAATFVSATGEPISDRRCFV

Query:  CGDPSHFANVCPNRGA
        CGDPSHFANVCPNRGA
Subjt:  CGDPSHFANVCPNRGA

XP_022982837.1 DNA topoisomerase 3-alpha isoform X1 [Cucurbita maxima]

0.0e+00

90.94

Show/hide

Query:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK
        M+GGRPITVLNVAEKPSVAK+VATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEF+ERYRKWHSCDP ELF APV K VPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCT VNRHLNIKRAHFSALIERDIHEA QNLVQPNK+FADAVDARQEIDLRIGASFTRFQTMLL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY
        KDAFNIDSV DD+N+VLSYGPCQFPTLGFVVERYW+IQSHEPEEFWTINCSHNS DG+STFSWTRGNLFDYTCAV+LYEMCV+ESTATV+NVRRQETLKY
Subjt:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETD FSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTY SGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRF+PTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAV EG KRKDEVLATCLQQMK+C
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC

Query:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ
        FLDAR NK KLFEAMEVFFERSNGSGGDENHAVGEVV+RC LCQDSDM LKRNR             CRNV+WLPGS+AEAAVTSN CNSCTPGPVYLIQ
Subjt:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ

Query:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNC
        FKFRQLEIPPNY+ N+LGCIGGCDDILRQLTEICGTGSR+SARGRGTSSSS+QRGNT +SVC FCQQ+ H+SN CPSQ VGSRSARHRQ+GESS SCSNC
Subjt:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNC

Query:  STPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNS-ARSNIRSSGSASSNPNPGRSTGRER----GRGRGQIAATFVSATGEPISDRRCFV
         TPCVLRTANT NNRGRKFYKC SQECNFF WED + + NGGNS A+SNIRSS SA+SN NPGR+TGR R    G+G+GQIAATFVSATGEPISDRRCFV
Subjt:  STPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNS-ARSNIRSSGSASSNPNPGRSTGRER----GRGRGQIAATFVSATGEPISDRRCFV

Query:  CGDPSHFANVCPNRGA
        CGDPSHFANVCPNRGA
Subjt:  CGDPSHFANVCPNRGA

XP_023526238.1 DNA topoisomerase 3-alpha isoform X1 [Cucurbita pepo subsp. pepo]

0.0e+00

90.35

Show/hide

Query:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK
        M+G RPITVLNVAEKPSVAK+VATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEF+ERYRKWHSCDP ELF APV K VPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCT VNRHLNIKRAHFSALIERDIHEA QNLVQPNK+FADAVDARQEIDLRIGASFTRFQTMLL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY
        KDAFNIDSV DD+N+VLSYGPCQFPTLGFVVERYW+IQSHEPEEFWTINCSHNS DG+STFSWTRGNLFDYTCAV+LYEMCV+ESTATV+NV+RQETLKY
Subjt:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETD FSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTY SGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRF+PTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAV EG KRKDEVLATCLQQMK+C
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC

Query:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ
        FLDAR NK KLFEAMEVFFERSNGSGGDENHAVGEVV+RC LCQDSDM LKRNR             CRNV+WLPGS+AEAAVTSN CNSCTPGPVYLIQ
Subjt:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ

Query:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNC
        FKFRQLEIPPNY+ N+LGCIGGCDDILRQLTEICGTGSR+SARGRGTSSSS+QRGNT  SVC FCQQ+ H+SN CPSQ VGSRSAR RQ+GESS SCSNC
Subjt:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNC

Query:  STPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNS-ARSNIRSSGSASSNPNPGRSTGRERGR----------GRGQIAATFVSATGEPIS
         TPCVLRTANT NNRGRKFYKC SQECNFF WED + + NGGNS ARSNIRSSGSA+SN NPGR+TGR RGR          G+GQIAATFVSATGEPIS
Subjt:  STPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNS-ARSNIRSSGSASSNPNPGRSTGRERGR----------GRGQIAATFVSATGEPIS

Query:  DRRCFVCGDPSHFANVCPNRGA
        DRRCFVCGDPSHFANVCPNRGA
Subjt:  DRRCFVCGDPSHFANVCPNRGA

XP_038904101.1 DNA topoisomerase 3-alpha isoform X1 [Benincasa hispida]

0.0e+00

91.23

Show/hide

Query:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK
        MSGGRPITVLNVAEKPSVAK+VATILSRNQGLRVR+GRSRYNKIFEFNYAIRGQSCNM+VTSVTGHLMELEF+ERYRKWHSCDP +LF APV K VPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        MDIKRTLEQEARRCQWL+LWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEA QNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY
        KDAFNIDSV DD+NIVLSYGPCQFPTLGFVVERYW+IQSHEPEEFWTINCSHNS DG+STFSWTRGNLFDYTCAV+ YEMCVQE TATV+NVRRQETLKY
Subjt:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETD FSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRF+PTNLGEALVMGYDDMGY LWKPHLRA+MEHEMKAV EGTKRKDEVLATCLQQMK+C
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC

Query:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ
        FLDAR+NK KL EAMEVFFERSNGSGGDEN AVGEVV+RCGLCQDS+M LKRNR             CRNV+WLPGS+AEAAVTS+CCN CTPGPVYLIQ
Subjt:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ

Query:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNC
        FKFRQLEIPPNY+AN+LGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSS+QR NT +SVC FCQQVGH+SN CPSQ VGSRSA  RQSGE SVSCSNC
Subjt:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNC

Query:  STPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNSA-RSNIRSSGSASSNPNPGRSTGRERGRGRGQIAATFVSATGEPISDRRCFVCGDP
         TPCVLRTANT NNRGRKFYKC SQECNFFVWED++ N NGGNSA RSNIR+SGSA+ NPNPGR+TGR RGRG  +IAATFVSATGEPISDRRCFVCGD 
Subjt:  STPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNSA-RSNIRSSGSASSNPNPGRSTGRERGRGRGQIAATFVSATGEPISDRRCFVCGDP

Query:  SHFANVCPNRGA
        SHFANVCPNRGA
Subjt:  SHFANVCPNRGA

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LBG7 DNA topoisomerase

0.0e+00

88.96

Show/hide

Query:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK
        MSGGR ITVLNVAEKPSVAK+VATILSRNQGLRVR+GRSRYNKIFEFNYAIRGQSCNM+VTSVTGHLMEL F+ERYRKWHSCDP +LF APV K VPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        +DIKRTLEQE+RR QWLVLWLDCDREGENIAFEVVEVCTAVN HLNIKRAHFSALIERDIH+A QNLVQPNKWFADAVDARQEIDLRIGASFTRFQT+LL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY
        KDAFNIDSVTDD+NIVLSYGPCQFPTLGFVVERYW+IQSHEPEEFWTINCSHNSDDG+STFSWTRGNLFDYTCAV+ YEMCVQESTATV+NVRRQETLKY
Subjt:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETD FSQRTDLHGIV+EQQEHQIWGAYAQRLLDP S LWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRF+PTNLGEALVMGYDDMGY LWKP+LRA+MEHEMKAV EGTKRKDEVLA+CLQQMKTC
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC

Query:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ
        FLDAR+NK KL EAMEVFFERSNGSGGDEN AVGEVV+ CGLCQDSDM LKRNR             CRNV+WLPGS+AEA VTS+ C  CTPGPVYLIQ
Subjt:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ

Query:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNC
        FKFRQLEIPPNY+AN+LGC+GGCDDILRQLTEICGTGSRVSARGRGTSSS++QR N G+SVC FCQQVGH+SN CPSQ VGSRSA+ RQSGESSVSCS+C
Subjt:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNC

Query:  STPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNSA-RSNIRSSGSASSNPNPGRSTGRERGRGR------------GQIAATFVSATGEP
         +PCVLRTANTANNRGRKFYKC SQECNFFVWED++ NGNGGNS  RSN+RSSGSA SN NPG++TGR RGRGR            GQIAATFVSATGEP
Subjt:  STPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNSA-RSNIRSSGSASSNPNPGRSTGRERGRGR------------GQIAATFVSATGEP

Query:  ISDRRCFVCGDPSHFANVCPNRGA
        ISDRRCFVCGDPSHFANVCPNRGA
Subjt:  ISDRRCFVCGDPSHFANVCPNRGA

A0A1S3B7B9 DNA topoisomerase

0.0e+00

89.15

Show/hide

Query:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK
        MSGGRPITVLNVAEKPSVAK+VATILSRNQGLRVR+GRSRYNKIFEFNYAIRGQSCNM+VTSVTGHLMEL F+ERYRKW+SCDP +LF APV K VPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        +DIKRTLEQEARR QWLVLWLDCDREGENIAFEVVEVCTAVN HLNIKRAHFSALIERDIHEA QNLVQPNKWFADAVDARQEIDLRIGASFTRFQT+LL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY
        KDAFNIDSVTDD+NIVLSYGPCQFPTLGFVVERYW+IQ+HEPEEFWTINCSHNSDDG+STFSWTRGNLFDYTCAV+ YEMCVQESTATV+NVRRQETLKY
Subjt:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETD FSQRTDLHGIV+EQQEHQIWGAYAQRLLDP SGLWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRF+PT+LGEALVMGYDDMGY LWKPHLRA+MEHEMKAV EGTKRKDEVLA+CLQQMK C
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC

Query:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ
        FLDAR+NK KL EAMEVFFERSNGSGGDEN AVGEVV+ CGLCQ+SDM LKRNR             CRNV+WLPGS+AEA VTS+ C  CTPGPVYLIQ
Subjt:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ

Query:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNC
        FKFRQLEIPPNY+AN+LGC+GGCDDILRQLTEICGTGSRVSARGRGTSSS++QR N G+SVC FCQQVGH+SN CPSQ VGS SAR RQSGESSVSCS+C
Subjt:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNC

Query:  STPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNSA-RSNIRSSGSASSNPNPGRSTGRERGR----------GRGQIAATFVSATGEPIS
         TPCVLRTANT NNRGRKFYKC SQECNFFVWED++ N NGGNSA RSN+RSSGSA SNPNPG++TGR RGR          G+GQIAATFVSATGEPIS
Subjt:  STPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNSA-RSNIRSSGSASSNPNPGRSTGRERGR----------GRGQIAATFVSATGEPIS

Query:  DRRCFVCGDPSHFANVCPNRGA
        DRRCFVCGDPSHFANVCPNRGA
Subjt:  DRRCFVCGDPSHFANVCPNRGA

A0A6J1DNA0 DNA topoisomerase

0.0e+00

90.58

Show/hide

Query:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK
        MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVR+GRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEF+ERYRKWHSCDPA+LF APV K VPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVV+VCTAVNRHL IKRAHFSALIERDIHEA QNLVQPN+WFADAVDARQEIDLRIGASFTRFQTMLL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY
        KDAF IDSVTDDKN++LSYGPCQFPTLGFVVERYW+IQSHEPEEFWTINCSHNSDDG+STFSWTRG+LFDYTCAV+LYEMCVQESTATV+NVRRQETLKY
Subjt:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLH IVQEQQ HQIWGAYAQRLLDPGSGLWRNPS GGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHH+LYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKD NTRF+PTNLGEALVMGYDDMGYKLWKP+LRA+MEHEMKAV EGTKRK EVLA  LQQMKTC
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC

Query:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ
        FLDARLNKLKL EAMEVFFERSNGSGGDE+H VG VVRRCGLCQDSDM LKRNR             CRNV+WLPGS+AEAAVT +CCNSCTPGPVYLIQ
Subjt:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ

Query:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRG-TSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSN
        FKFR LEIPPNY+AN+LGCIGGCDDILRQLTEICGTGSR+S RGRG TSSSS QRGNTG+ VC  CQQVGH+SN CPSQ VGSRSAR RQSGESSVSCSN
Subjt:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRG-TSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSN

Query:  CSTPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNSA-RSNIRSSGSASSNPNPGRSTGRERGRGRGQIAATFVSATGEPISDRRCFVCGD
        C TPCVLRTANTANNRGRKFY C SQ+CNFFVWED++ +GNGGNSA RSNIR S S +SNPNPG++TG  RGRGRG IA TFVSATGEPISDRRCFVCGD
Subjt:  CSTPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNSA-RSNIRSSGSASSNPNPGRSTGRERGRGRGQIAATFVSATGEPISDRRCFVCGD

Query:  PSHFANVCPNRGA
        PSHFANVCPNRGA
Subjt:  PSHFANVCPNRGA

A0A6J1F0T9 DNA topoisomerase

0.0e+00

90.72

Show/hide

Query:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK
        M+GGRPITVLNVAEKPSVAK+VATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEF+ERYRKWHSCDP ELF APV K VPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        MDIKRTLEQEA RCQWLVLWLDCDREGENIAFEVVEVCT VNRHLNIKRAHFSALIERDIHEA QNLVQPNK++ADAVDARQEIDLRIGASFTRFQTMLL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY
        KDAFNIDSV DD+N+VLSYGPCQFPTLGFVVERYW+IQSHEPEEFWTINCSHNS DG+STFSWTRGNLFDYTCAV+LYEMCV+ESTATV+NV+RQETLKY
Subjt:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETD FSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTY SGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRF+PTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAV EG KRKDEVLATCLQQMK+C
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC

Query:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ
        FLDAR NK KLFEAMEVFFERSNGSGGDENHAVGEVV+RC LCQDSDM LKRNR             CRNV+WLPGS+AEAAVTSN CNSCTPGPVYLIQ
Subjt:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ

Query:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNC
        FKFRQLEIPPNY+ N+LGCIGGCDDILRQLTEICGTGSR+SARGRGTSSSS+QRGNT +SVC FCQQ+ H+SN CPSQ VGSRSAR RQ+GESS SCSNC
Subjt:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNC

Query:  STPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNS-ARSNIRSSGSASSNPNPGRSTGRERGR----GRGQIAATFVSATGEPISDRRCFV
         TPCVLRTANT NNRGRKFYKC SQECNFF WED + + NGGNS ARSNIRSSGSA+SN NPGR+TGR RGR    G+GQIAATFVSA GEPISDRRCFV
Subjt:  STPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNS-ARSNIRSSGSASSNPNPGRSTGRERGR----GRGQIAATFVSATGEPISDRRCFV

Query:  CGDPSHFANVCPNRGA
        CGDPSHFANVCPNRGA
Subjt:  CGDPSHFANVCPNRGA

A0A6J1IXM8 DNA topoisomerase

0.0e+00

90.94

Show/hide

Query:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK
        M+GGRPITVLNVAEKPSVAK+VATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEF+ERYRKWHSCDP ELF APV K VPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCT VNRHLNIKRAHFSALIERDIHEA QNLVQPNK+FADAVDARQEIDLRIGASFTRFQTMLL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY
        KDAFNIDSV DD+N+VLSYGPCQFPTLGFVVERYW+IQSHEPEEFWTINCSHNS DG+STFSWTRGNLFDYTCAV+LYEMCV+ESTATV+NVRRQETLKY
Subjt:  KDAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETD FSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTY SGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRF+PTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAV EG KRKDEVLATCLQQMK+C
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTC

Query:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ
        FLDAR NK KLFEAMEVFFERSNGSGGDENHAVGEVV+RC LCQDSDM LKRNR             CRNV+WLPGS+AEAAVTSN CNSCTPGPVYLIQ
Subjt:  FLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQ

Query:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNC
        FKFRQLEIPPNY+ N+LGCIGGCDDILRQLTEICGTGSR+SARGRGTSSSS+QRGNT +SVC FCQQ+ H+SN CPSQ VGSRSARHRQ+GESS SCSNC
Subjt:  FKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNC

Query:  STPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNS-ARSNIRSSGSASSNPNPGRSTGRER----GRGRGQIAATFVSATGEPISDRRCFV
         TPCVLRTANT NNRGRKFYKC SQECNFF WED + + NGGNS A+SNIRSS SA+SN NPGR+TGR R    G+G+GQIAATFVSATGEPISDRRCFV
Subjt:  STPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNS-ARSNIRSSGSASSNPNPGRSTGRER----GRGRGQIAATFVSATGEPISDRRCFV

Query:  CGDPSHFANVCPNRGA
        CGDPSHFANVCPNRGA
Subjt:  CGDPSHFANVCPNRGA

SwissProt top hits

e value

%identity

Alignment

C7J0A2 DNA topoisomerase 3-alpha

0.0e+00

66.67

Show/hide

Query:  GGRPITVLNVAEKPSVAKAVATILSR-NQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDKM
        GG  I VLNVAEKPSVAK+VA ILSR + G+R REGRSRYN++FEF+Y+I G++C+MLVTSVTGHLMELEFD+R+R+WHSCDPA+LF APV KSVP+DK 
Subjt:  GGRPITVLNVAEKPSVAKAVATILSR-NQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDKM

Query:  DIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLK
        DIKRTLE+EAR+CQWLVLWLDCDREGENIA+EV+++C   N  LNI RA FSALI+R+IHEA Q+L +PNK FADAVDARQEIDLRIGASFTRFQTMLLK
Subjt:  DIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLK

Query:  DAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKYP
        DAF +D   DD+NI+LSYGPCQFPTLGF+VER+W+IQ+HEPEEFWTINCSH SD+G ++F W RG+LFDY+ AV++YEMCV+E  ATV NVR QE LKYP
Subjt:  DAFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKYP

Query:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHPT
        P+PL+TIEL+KRASRYFRMSSEHTMKVAE+LYQAGFISYPRTETD FS  TDLH IV EQ  H  WG YAQRLLDP + LWRNPS GGHDDKAHPPIHPT
Subjt:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHPT

Query:  KFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPL
        KFSAGE  W+ +H +LYELVVRHFLAC SQPAVGA TTVEIDIAGE F+ SGR++LA+NYLDVYRF+SWGG+ +PTY+ GQQFVPTTLTLDSG+TRPPPL
Subjt:  KFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPL

Query:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTCF
        L+EADLL CMDK GIGTDATMHDHIKKLLDR YATKDANTRFSPTNLGEALVMGYD+MGY+LWKP+LR++ME +MK+V  GTK K EVL  CLQQMK CF
Subjt:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTCF

Query:  LDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRN-------------RCRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQF
        LDAR NK+KLF+AM  FF RS+    +  +++ E VR C  C +S+M LK+              +CRNV+WLP S++ AAVT   C +C PGPVY IQF
Subjt:  LDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRN-------------RCRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQF

Query:  KFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSR----VSARGRGTSSSSMQRGNTGRSV-CSFCQQVGHTSNVCP-SQGVGSRSARHRQSGESS-
        KFR+ +IPPN+D ++LGCIGGCDDIL++L E+   GS       AR +  ++S +++G++ + +  SF   V  T+   P     G RS   + SG +S 
Subjt:  KFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSR----VSARGRGTSSSSMQRGNTGRSV-CSFCQQVGHTSNVCP-SQGVGSRSARHRQSGESS-

Query:  -VSCSNCSTPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDL------GNGNGGNSARSNIRSSGSASSNPNPGRSTGR-ERGRGRGQIAATFVSATGE
         V C++C  PCVLRTANT  NRGRKFYKC +  C FF WEDD+      G G  G   RS+ R S +++S    G + GR  RGRGR      FV+ATGE
Subjt:  -VSCSNCSTPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDL------GNGNGGNSARSNIRSSGSASSNPNPGRSTGR-ERGRGRGQIAATFVSATGE

Query:  PISDRRCFVCGDPSHFANVCPNRG
        P+    CF+CGDP+HFANVCPN G
Subjt:  PISDRRCFVCGDPSHFANVCPNRG

O70157 DNA topoisomerase 3-alpha

8.4e-192

41.9

Show/hide

Query:  VLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDKMDIKRTLE
        VL VAEK   AK +A +LS N  +R +EG S++NKI+EF+Y + GQ+  M++TSV+GHL+  +F  ++RKW SC+P  LF A + K  PE+ +DIK+TLE
Subjt:  VLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDKMDIKRTLE

Query:  QEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNIDS
        +E   CQ LV+W DCDREGENI FE++ VC AV  +L + RA FS +    +  A +NL +P++  +DAVD RQE+DLRIGA+FTRFQT+ L+  F    
Subjt:  QEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNIDS

Query:  VTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKYPPHPLNTI
        V  ++  ++SYG CQFPTLGFVVER+  IQ+  PE F  I  +H+  DG   F+W R  LF++T  ++LY++C+++  ATV+ VR +   K+ P  L+T+
Subjt:  VTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKYPPHPLNTI

Query:  ELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHPTKFSAGER
        ELEK ASR  R++++ TM++AE LY  G+ISYPRTET+ F +  +L  +V++Q     WGA+AQ +L+ G      P  G   D+AHPPIHPTK+++G +
Subjt:  ELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHPTKFSAGER

Query:  GWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLL
        G   D  RLYE +VRHFLAC SQ A G  TTVEIDIA E F   G +ILARNYLDVY ++ W    +P Y  G  F P+T+ +  G T PP LL+EADL+
Subjt:  GWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLL

Query:  SCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTCFLDARLNK
        + M+K GIGTDAT  +HI+ +  R Y    ++ RF P +LG  LV GYD MGY++ KP LRA +E ++K + EG K K +VL   +Q+ K  F++A    
Subjt:  SCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTCFLDARLNK

Query:  LKLFEAMEVFF-ERSNGSGGDENH-AVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQFKFRQL
         KL EA+  +  ER+  +  +E + A+ E VR+C  C + DM LK  +             CR+ +W P SV EA+  ++ C+ C P PVY ++ KF++ 
Subjt:  LKLFEAMEVFF-ERSNGSGGDENH-AVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQFKFRQL

Query:  EIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSA---RGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNCSTP
         +PP     ++GCIGGCD+ L+++  +    +   A    G   +S ++ R ++ +   S      HT    PS+ V         +GES+    NC   
Subjt:  EIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSA---RGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNCSTP

Query:  CVLRTANTAN-NRGRKFYKCSSQECNFFVWEDDLGNGNGGNSAR------SNIRSSGSASSNPNPGRSTGRERGRGR----GQIAATFVSATGEPISDRR
         VL T      N+GR FYKCS+ +CNFF+W D   +  GG          S++    S  S+ +   S G +   G     GQ A T       P   R+
Subjt:  CVLRTANTAN-NRGRKFYKCSSQECNFFVWEDDLGNGNGGNSAR------SNIRSSGSASSNPNPGRSTGRERGRGR----GQIAATFVSATGEPISDRR

Query:  CFVCGDP
           C  P
Subjt:  CFVCGDP

Q13472 DNA topoisomerase 3-alpha

1.5e-193

42.87

Show/hide

Query:  VLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDKMDIKRTLE
        VL VAEK   AK +A +LS N  +R REG S++NKI+EF+Y + GQ+  M++TSV+GHL+  +F  ++RKW SC+P  LF A + K  PE+ +DIK+TLE
Subjt:  VLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDKMDIKRTLE

Query:  QEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNIDS
        +E R+CQ LV+W DCDREGENI FE++ VC AV  +L + RA FS +    +  A +NL +P++  +DAVD RQE+DLRIGA+FTRFQT+ L+  F    
Subjt:  QEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNIDS

Query:  VTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKYPPHPLNTI
        V  ++  ++SYG CQFPTLGFVVER+  IQ+  PE F  I  +H+  DG+  F+W R  LF++T  ++LY++CV++  ATV+ VR +   K+ P  L+T+
Subjt:  VTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKYPPHPLNTI

Query:  ELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHPTKFSAGER
        ELEK ASR  R++++ TM++AE LY  G+ISYPRTET+ F +  +L  +V++Q     WGA+AQ +L+ G      P  G   D+AHPPIHPTK++   +
Subjt:  ELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHPTKFSAGER

Query:  GWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLL
        G   D  RLYE +VRHFLAC SQ A G  TTVEIDIA E F   G MILARNYLDVY ++ W    +P Y  G  F P+T+ +  G T PP LL+EADL+
Subjt:  GWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLL

Query:  SCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTCFLDARLNK
        + M+K GIGTDAT  +HI+ +  R Y     + RF P +LG  LV GYD MGY++ KP LRA +E ++K + +G K K  VL   +Q+ K  F++A    
Subjt:  SCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTCFLDARLNK

Query:  LKLFEAMEVFFERSNGSGGDEN--HAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQFKFRQL
         KL EA+  +F         E+   A+ E +R+C  C + DM LK  +             CR+ +WLP SV EA+  S+ C  C P PVY ++ KF++ 
Subjt:  LKLFEAMEVFFERSNGSGGDEN--HAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQFKFRQL

Query:  EIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSA---RGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNCSTP
         +PP     ++ CIGGCDD LR++ ++  +G    A    GR  ++ S+ R +  +       Q   +     S+ +         +GES+    NC   
Subjt:  EIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSA---RGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNCSTP

Query:  CVLRTANTAN-NRGRKFYKCSSQECNFFVWEDDLGNGNGGNSARSNIRSSGSASSNPNPGRSTGRERGRGRGQIAAT
         VL T      NRGR+F+KC+   CNFF+W D    G GG  A +      S    P PG   G     G G  + T
Subjt:  CVLRTANTAN-NRGRKFYKCSSQECNFFVWEDDLGNGNGGNSARSNIRSSGSASSNPNPGRSTGRERGRGRGQIAAT

Q8T2T7 DNA topoisomerase 3

4.8e-163

46.46

Show/hide

Query:  VLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRG-QSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDKMDIKRTL
        +LNVAEKPS AK +A ILS N+   VREG S+YNK+++F Y I     C M  TSVTGHLME++  E+++ W SCDP +LF AP+ K+VP DK  +K+TL
Subjt:  VLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRG-QSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDKMDIKRTL

Query:  EQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNID
        E+E ++   L+LWLDCDREGENIAFEV+EVC    +     RAHFSA+I R+I  A +NL +PN+  + AVD R EIDLRIGA+FTRFQT+ LK  F I 
Subjt:  EQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNID

Query:  SVTDDK---------NI------------VLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLS------TFSWTRGNLFDYTCAVLLYEM
        S +D++         NI            ++SYGPCQFPTLGFVVERY+ I + +PE+FW ++  H   D  S      TFSW R  LFDYT A +LYE 
Subjt:  SVTDDK---------NI------------VLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLS------TFSWTRGNLFDYTCAVLLYEM

Query:  CVQESTATVINVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSG
        C+  + ATV++V  +E+ +Y P PL TIEL+K AS+  R+SS  TM+ AE+LY  G ISYPRTETD F   TDL G++  Q  +  WGAYA RL++    
Subjt:  CVQESTATVINVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSG

Query:  LWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVS
        ++  P  G ++D +HPPIHPT  + G  G   +  ++Y+ + R FLAC S+ +V A TTV IDI GE FS +G M+L   YL+VY F+      IPTY  
Subjt:  LWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVS

Query:  GQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVG
        G++F P  + L  G T  P  ++EA+LL+ MD   IGTDATM  HI+ + DRFY  K+ + +F P+NLG +LV  Y+ MG++  KP+LRA +E ++  + 
Subjt:  GQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVG

Query:  EGTKRKDEVLATCLQQMKTCFLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLC
         G K K EVL + +++ K  +  A  N      +   ++E ++  GG+    V +   RCG C
Subjt:  EGTKRKDEVLATCLQQMKTCFLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLC

Q9LVP1 DNA topoisomerase 3-alpha

0.0e+00

69.62

Show/hide

Query:  GGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDKMD
        GG P+TVLNVAEKPSVAK+VA ILSR    R REGRSRYNKIFEF+YAI GQ C ML+TSV GHLMELEF +RYRKWHSCDPA+L++APV K VPEDK D
Subjt:  GGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDKMD

Query:  IKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKD
        IK+TLE+EAR+  WLVLWLDCDREGENIAFEVV+VC AV  +L I+RAHFSALI+RDIHEA QNL  PN+ FA+AVDARQEIDLRIGASFTRFQTMLL+D
Subjt:  IKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKD

Query:  AFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINV-RRQETLKYP
         F IDS  ++++ V+SYGPCQFPTLGF+VERYW+IQ+HEPEEFWTINCSH S++GL+TF+W RG+LFDY  AV+LYEMCV+E TATV+NV   +E  KYP
Subjt:  AFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINV-RRQETLKYP

Query:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHPT
        P+PLNTIELEKRASRYFR+SSEHTMKVAE+LYQAGFISYPRTETD FS RTDL  +V+EQ  H  WG+YAQRLL+P  GLWRNP+ GGHDDKAHPPIHPT
Subjt:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHPT

Query:  KFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPL
        KFS+GE  WS+DH  +YELVVRH+LACVSQPAV A TTVEIDIAGE FS SGR ILA+NYL+VYRFESWGGS IP Y  GQQF+PTTLTLD+ VTRPPPL
Subjt:  KFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPL

Query:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTCF
        L EADLLSCMDK GIGTDATMHDHIKKLLDR YATKDANTRFSPTNLGEALVMGYDDMGY+LWKP+LRALMEH+M  V  G K K EVL TCLQQMK CF
Subjt:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTCF

Query:  LDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQF
        LDAR+ K KL EAM +FFERSN +   E+   GEVVRRC LC +SDMAL++NR             CRN +WLPG   EA+VT+N C SC PGPVY I F
Subjt:  LDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQF

Query:  KFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGR-GTS-SSSMQRGNTGRS-VCSFCQQVGHTSNVCPSQGVGSRSAR----HRQSGESS
        KFRQ+ IPP +D N+LGC+GGCDDIL+QL +ICGTGSR  AR   GT+ S+++Q  NT +S VC  CQQ GH S  CPS+   SR++R    + ++ ES+
Subjt:  KFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGR-GTS-SSSMQRGNTGRS-VCSFCQQVGHTSNVCPSQGVGSRSAR----HRQSGESS

Query:  VSCSNCSTPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNSARSNIRSSGSASSNPNPGRSTGRERGRGRGQIAATFVSATGEPISDRRCF
        VSC+ C + CVLRTANT  NRGR+F+ C +Q C+FF WED + N +G  +  SN   SG   S        G +   GR     +FVSATGEP+S  RCF
Subjt:  VSCSNCSTPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNSARSNIRSSGSASSNPNPGRSTGRERGRGRGQIAATFVSATGEPISDRRCF

Query:  VCGDPSHFANVCPNR
         CGDPSHFAN CPNR
Subjt:  VCGDPSHFANVCPNR

Arabidopsis top hits

e value

%identity

Alignment

AT2G32000.1 DNA topoisomerase, type IA, core

1.7e-110

36.56

Show/hide

Query:  ITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDKMDIKRT
        + VL VAEKPS+A ++A++LS  Q +  R G +   ++ EF+   RG   +  VTSV GH+  ++F E+Y+ W + DP +LF AP+ K     K  I R 
Subjt:  ITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDKMDIKRT

Query:  LEQEARRCQWLVLWLDCDREGENIAFEVVEVC--TAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAF
        L  EAR C ++VLWLDCDREGENI FEV+E       +    + RA FS++ E+DI +A  NLV+PN+  A AVDARQEIDL++G +F+RFQT   +  +
Subjt:  LEQEARRCQWLVLWLDCDREGENIAFEVVEVC--TAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAF

Query:  -NIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKYPPH
         N+D        V+SYGPCQ PTLGF V+RY  I + +PE+FW +      D       W R  LFD   A +  ++ V+  TA V++V  ++ +K  P 
Subjt:  -NIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKYPPH

Query:  PLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHPTKF
         LNT+ L K AS       +  M +AE LY  GFISYPRTE+  +    D    ++ Q  + +WG Y QRLL  G  + ++    G D   HPPI P + 
Subjt:  PLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHPTKF

Query:  SAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLS
        +A E     D  RLY+ V +HFL  VS       T VE+ I GE F  +G+ +  + +  +  + +     +P+++ G++     + L  G T PP  L+
Subjt:  SAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLS

Query:  EADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTCFLD
        E++L+S M+K GIGTDA++  HI  + +R Y    +  +  PT LG  L+ GY  +   L  P +R+ +E ++  V +G      V+   +QQ +  F  
Subjt:  EADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTCFLD

Query:  ARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLC
             ++  E M+  FE       D     G  + +CG C
Subjt:  ARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLC

AT2G32000.2 DNA topoisomerase, type IA, core

6.5e-99

36.21

Show/hide

Query:  LMELEFDERYRKWHSCDPAELFRAPVSKSVPEDKMDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVC--TAVNRHLNIKRAHFSALIERDIHEAA
        +M  +F E+Y+ W + DP +LF AP+ K     K  I R L  EAR C ++VLWLDCDREGENI FEV+E       +    + RA FS++ E+DI +A 
Subjt:  LMELEFDERYRKWHSCDPAELFRAPVSKSVPEDKMDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVC--TAVNRHLNIKRAHFSALIERDIHEAA

Query:  QNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAF-NIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSW
         NLV+PN+  A AVDARQEIDL++G +F+RFQT   +  + N+D        V+SYGPCQ PTLGF V+RY  I + +PE+FW +      D       W
Subjt:  QNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAF-NIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSW

Query:  TRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQE
         R  LFD   A +  ++ V+  TA V++V  ++ +K  P  LNT+ L K AS       +  M +AE LY  GFISYPRTE+  +    D    ++ Q  
Subjt:  TRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQE

Query:  HQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLD
        + +WG Y QRLL  G  + ++    G D   HPPI P + +A E     D  RLY+ V +HFL  VS       T VE+ I GE F  +G+ +  + +  
Subjt:  HQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLD

Query:  VYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKL
        +  + +     +P+++ G++     + L  G T PP  L+E++L+S M+K GIGTDA++  HI  + +R Y    +  +  PT LG  L+ GY  +   L
Subjt:  VYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKL

Query:  WKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTCFLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLC
          P +R+ +E ++  V +G      V+   +QQ +  F       ++  E M+  FE       D     G  + +CG C
Subjt:  WKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTCFLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLC

AT4G31210.1 DNA topoisomerase, type IA, core

5.7e-18

24.36

Show/hide

Query:  LVLWLDCDREGENIAFEVVEVCT---AVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNIDSVTDDK
        L+L  D DREGE IA+ ++E+     A++  + + R  F  + E  I  A Q+  + +     A  AR+ +D  IG              FNI  +   K
Subjt:  LVLWLDCDREGENIAFEVVEVCT---AVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNIDSVTDDK

Query:  -NIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLL---------YEMCVQESTATVINVRRQETLKYPPH
             S G  Q   L  V +R  +I   +P+E+WT+       D  +TFS    +L       L           E  ++     V   +   T K PP 
Subjt:  -NIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLL---------YEMCVQESTATVINVRRQETLKYPPH

Query:  PLNTIELEKRASRYFRMSSEHTMKVAEDLYQ---------AGFISYPRTETDGFSQRT--DLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDD
        P  T  L++ A+     S+ HTMK+A+ LY+         AG I+Y RT+    +     D+  +V E+          ++                +  
Subjt:  PLNTIELEKRASRYFRMSSEHTMKVAEDLYQ---------AGFISYPRTETDGFSQRT--DLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDD

Query:  KAHPPIHPTKF----SAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGE--LFSTSGRMILARNYLDVY------------------RFE
        +AH  I PT      S        D  +LY L+    +AC  +PA  A   ++I  A E  +F +S   +    Y  VY                  R E
Subjt:  KAHPPIHPTKF----SAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGE--LFSTSGRMILARNYLDVY------------------RFE

Query:  SWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYAT
        ++   T+ +   G       + L    T+ PP  SE  L+  +++ GIG  +T     + L  R Y T
Subjt:  SWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYAT

AT5G13920.1 GRF zinc finger / Zinc knuckle protein

3.2e-05

34.52

Show/hide

Query:  MQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNCSTPCVLRTANTANNRGRKFYKC-SSQECNFFVWED
        M  G      C  C+Q GH  N CP +        +      ++ C      C ++ ANT  N GRKFYKC ++Q C FF W D
Subjt:  MQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSRSARHRQSGESSVSCSNCSTPCVLRTANTANNRGRKFYKC-SSQECNFFVWED

AT5G63920.1 topoisomerase 3alpha

0.0e+00

69.62

Show/hide

Query:  GGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDKMD
        GG P+TVLNVAEKPSVAK+VA ILSR    R REGRSRYNKIFEF+YAI GQ C ML+TSV GHLMELEF +RYRKWHSCDPA+L++APV K VPEDK D
Subjt:  GGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDKMD

Query:  IKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKD
        IK+TLE+EAR+  WLVLWLDCDREGENIAFEVV+VC AV  +L I+RAHFSALI+RDIHEA QNL  PN+ FA+AVDARQEIDLRIGASFTRFQTMLL+D
Subjt:  IKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKD

Query:  AFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINV-RRQETLKYP
         F IDS  ++++ V+SYGPCQFPTLGF+VERYW+IQ+HEPEEFWTINCSH S++GL+TF+W RG+LFDY  AV+LYEMCV+E TATV+NV   +E  KYP
Subjt:  AFNIDSVTDDKNIVLSYGPCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINV-RRQETLKYP

Query:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHPT
        P+PLNTIELEKRASRYFR+SSEHTMKVAE+LYQAGFISYPRTETD FS RTDL  +V+EQ  H  WG+YAQRLL+P  GLWRNP+ GGHDDKAHPPIHPT
Subjt:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHPT

Query:  KFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPL
        KFS+GE  WS+DH  +YELVVRH+LACVSQPAV A TTVEIDIAGE FS SGR ILA+NYL+VYRFESWGGS IP Y  GQQF+PTTLTLD+ VTRPPPL
Subjt:  KFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPL

Query:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTCF
        L EADLLSCMDK GIGTDATMHDHIKKLLDR YATKDANTRFSPTNLGEALVMGYDDMGY+LWKP+LRALMEH+M  V  G K K EVL TCLQQMK CF
Subjt:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGEALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTCF

Query:  LDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQF
        LDAR+ K KL EAM +FFERSN +   E+   GEVVRRC LC +SDMAL++NR             CRN +WLPG   EA+VT+N C SC PGPVY I F
Subjt:  LDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNR-------------CRNVIWLPGSVAEAAVTSNCCNSCTPGPVYLIQF

Query:  KFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGR-GTS-SSSMQRGNTGRS-VCSFCQQVGHTSNVCPSQGVGSRSAR----HRQSGESS
        KFRQ+ IPP +D N+LGC+GGCDDIL+QL +ICGTGSR  AR   GT+ S+++Q  NT +S VC  CQQ GH S  CPS+   SR++R    + ++ ES+
Subjt:  KFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGR-GTS-SSSMQRGNTGRS-VCSFCQQVGHTSNVCPSQGVGSRSAR----HRQSGESS

Query:  VSCSNCSTPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNSARSNIRSSGSASSNPNPGRSTGRERGRGRGQIAATFVSATGEPISDRRCF
        VSC+ C + CVLRTANT  NRGR+F+ C +Q C+FF WED + N +G  +  SN   SG   S        G +   GR     +FVSATGEP+S  RCF
Subjt:  VSCSNCSTPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNSARSNIRSSGSASSNPNPGRSTGRERGRGRGQIAATFVSATGEPISDRRCF

Query:  VCGDPSHFANVCPNR
         CGDPSHFAN CPNR
Subjt:  VCGDPSHFANVCPNR

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGTCCGGCGGCCGTCCGATCACCGTCCTCAACGTAGCGGAGAAGCCATCGGTGGCGAAGGCGGTGGCCACCATACTCTCGAGGAACCAGGGCCTTCGAGTTCGCGAAGG
TCGTTCTCGCTACAACAAGATTTTCGAGTTCAACTACGCCATTCGAGGCCAGTCTTGCAATATGCTCGTCACCTCCGTCACTGGCCATTTGATGGAGCTCGAGTTCGATG
AACGCTACCGCAAATGGCATTCCTGTGACCCGGCCGAGCTCTTCCGGGCTCCCGTTAGCAAATCTGTCCCCGAGGACAAGATGGATATAAAGAGGACGTTGGAACAAGAA
GCTAGAAGGTGCCAATGGCTCGTCCTTTGGCTTGATTGTGATAGAGAAGGAGAGAATATTGCATTTGAAGTTGTGGAAGTTTGCACAGCAGTGAATCGTCATCTTAACAT
TAAGAGGGCTCACTTCTCTGCTTTGATTGAAAGGGATATTCATGAAGCTGCGCAAAATCTTGTCCAACCAAATAAGTGGTTTGCTGATGCAGTTGATGCTAGACAAGAAA
TTGATCTAAGAATTGGTGCTTCTTTCACTAGGTTCCAAACTATGCTGTTGAAAGATGCATTTAATATTGATTCTGTCACTGATGACAAAAATATTGTTTTGAGTTATGGG
CCATGTCAGTTTCCTACTCTTGGTTTTGTTGTTGAGCGGTACTGGGATATTCAGTCCCACGAGCCAGAAGAATTTTGGACGATCAACTGTTCACACAATTCCGATGATGG
ACTTTCTACATTTAGTTGGACGAGAGGGAATCTATTTGATTATACTTGTGCTGTGTTACTATATGAAATGTGTGTACAAGAATCGACTGCTACTGTTATAAATGTTAGAC
GACAAGAGACGTTGAAGTATCCTCCACATCCATTGAATACAATTGAGCTTGAAAAACGAGCTTCACGGTACTTTCGAATGAGTTCTGAACATACCATGAAGGTGGCCGAA
GATCTCTACCAAGCAGGTTTCATTAGTTATCCTCGTACAGAGACTGATGGCTTTTCTCAAAGAACCGATCTTCATGGGATTGTGCAAGAACAACAAGAACACCAAATATG
GGGAGCCTATGCACAAAGGTTGTTGGATCCTGGATCAGGACTTTGGAGGAATCCTAGTGGTGGTGGCCATGATGACAAAGCCCATCCACCTATTCACCCAACAAAGTTTT
CGGCAGGGGAACGGGGATGGAGCCAAGATCATCATAGATTATATGAGCTAGTTGTTCGCCACTTCCTTGCATGTGTTTCACAACCAGCTGTAGGTGCTGTGACTACCGTT
GAAATTGATATTGCTGGTGAATTGTTTTCTACATCTGGGAGAATGATACTGGCAAGAAATTACCTGGATGTTTACCGCTTTGAATCATGGGGAGGTTCAACCATTCCAAC
TTACGTTTCTGGGCAACAGTTTGTTCCTACAACATTAACTCTTGATTCGGGAGTCACGAGACCACCTCCTCTTCTGAGTGAAGCTGATTTGCTTTCTTGTATGGATAAGG
AGGGAATAGGTACTGATGCAACGATGCATGACCACATCAAGAAGCTGTTGGATAGATTTTATGCAACGAAGGATGCAAACACTCGTTTCTCACCAACTAACCTTGGTGAG
GCTCTGGTTATGGGATATGATGACATGGGGTATAAACTGTGGAAACCTCACCTTAGAGCCCTCATGGAGCATGAGATGAAAGCAGTTGGCGAGGGCACTAAGAGAAAAGA
TGAAGTGTTGGCTACATGCTTGCAGCAAATGAAAACTTGCTTCTTAGATGCAAGGTTGAATAAGCTAAAACTTTTTGAAGCCATGGAGGTTTTCTTTGAGAGATCTAATG
GTTCTGGTGGAGATGAAAATCATGCAGTTGGAGAAGTTGTTCGGCGATGTGGACTGTGTCAGGACTCGGATATGGCGCTTAAAAGAAATAGGTGTAGAAATGTTATCTGG
CTCCCTGGATCCGTTGCAGAAGCTGCGGTAACCTCTAATTGTTGCAACTCATGCACTCCAGGTCCTGTTTACTTGATCCAGTTTAAGTTTCGTCAGCTGGAAATACCACC
AAACTACGATGCTAACTACTTGGGCTGTATAGGTGGTTGCGATGATATTCTTAGGCAATTGACAGAAATCTGTGGTACTGGATCCCGCGTATCAGCGAGAGGTCGAGGGA
CTTCTTCATCCAGCATGCAGCGAGGTAACACCGGGCGAAGTGTATGCAGTTTCTGCCAACAAGTAGGCCATACCTCAAACGTTTGCCCTTCACAAGGTGTAGGGTCCAGA
AGTGCTCGTCATCGACAGAGTGGGGAATCTTCAGTTTCATGTAGCAACTGTAGCACACCATGCGTCTTACGGACTGCAAATACTGCCAATAACAGGGGAAGAAAATTCTA
CAAATGTTCATCTCAAGAGTGCAATTTCTTTGTATGGGAAGACGACCTGGGCAATGGCAATGGAGGAAATAGTGCTCGGTCAAATATCAGGAGCTCAGGCTCAGCATCAT
CTAATCCTAACCCTGGTCGGAGCACCGGGCGCGAGCGTGGTCGTGGTCGGGGTCAGATTGCAGCAACATTCGTGTCAGCAACTGGTGAGCCAATATCTGATAGAAGATGT
TTTGTTTGTGGCGATCCATCACACTTTGCAAATGTTTGCCCAAACCGTGGTGCTTGA

mRNA sequence

Show/hide mRNA sequence

Protein sequence

Show/hide protein sequence

MSGGRPITVLNVAEKPSVAKAVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFDERYRKWHSCDPAELFRAPVSKSVPEDKMDIKRTLEQE
ARRCQWLVLWLDCDREGENIAFEVVEVCTAVNRHLNIKRAHFSALIERDIHEAAQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNIDSVTDDKNIVLSYG
PCQFPTLGFVVERYWDIQSHEPEEFWTINCSHNSDDGLSTFSWTRGNLFDYTCAVLLYEMCVQESTATVINVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAE
DLYQAGFISYPRTETDGFSQRTDLHGIVQEQQEHQIWGAYAQRLLDPGSGLWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTV
EIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNLGE
ALVMGYDDMGYKLWKPHLRALMEHEMKAVGEGTKRKDEVLATCLQQMKTCFLDARLNKLKLFEAMEVFFERSNGSGGDENHAVGEVVRRCGLCQDSDMALKRNRCRNVIW
LPGSVAEAAVTSNCCNSCTPGPVYLIQFKFRQLEIPPNYDANYLGCIGGCDDILRQLTEICGTGSRVSARGRGTSSSSMQRGNTGRSVCSFCQQVGHTSNVCPSQGVGSR
SARHRQSGESSVSCSNCSTPCVLRTANTANNRGRKFYKCSSQECNFFVWEDDLGNGNGGNSARSNIRSSGSASSNPNPGRSTGRERGRGRGQIAATFVSATGEPISDRRC
FVCGDPSHFANVCPNRGA

Sed0010212 (gene) of Chayote v1 genome