CuGenDBv2

Gene ID	Sed0010250
Organism	Sechium edule (Chayote v1)
Description	Aha1_N domain-containing protein
Genome location	LG08:24693021..24696568
RNA-Seq Expression	Sed0010250
Synteny	Sed0010250
Gene Ontology terms	GO:0006457 - protein folding (biological process) GO:0032781 - positive regulation of ATPase activity (biological process) GO:0005829 - cytosol (cellular component) GO:0001671 - ATPase activator activity (molecular function) GO:0051087 - chaperone binding (molecular function) GO:0051879 - Hsp90 protein binding (molecular function)
InterPro domains	IPR015310 - Activator of Hsp90 ATPase, N-terminal IPR036338 - Activator of Hsp90 ATPase, Aha1 IPR039981 - Activator of 90kDa heat shock protein ATPase-like

Homology

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GenBank top hits

e value

%identity

Alignment

XP_008443651.1 PREDICTED: uncharacterized protein LOC103487198 [Cucumis melo]

1.2e-92

89.05

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Query:  MEN-GAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSK
        MEN GAVSS+TQQG+SYTYWVRE R DAAPLPVPRKLSA+DIL   AS PP LGSVWNRAGTWEEKNLNKWATDRMKELL SVASLEF+SGKAEIADVSK
Subjt:  MEN-GAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSK

Query:  CVGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKE
        CVGDAFLVTVRNKKRVGYTYELTLKIKGEWT+KQEKK VKGHID+PEFSFGELD+LQM+VRLSEEKDLL EDK QICQDLKRFLQPVREKLLQFE E+KE
Subjt:  CVGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKE

Query:  R
        R
Subjt:  R

XP_022933923.1 uncharacterized protein LOC111441189 [Cucurbita moschata]

1.2e-92

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Query:  MENGAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSKC
        MENGAVSS+TQQG+SYTYWVRE R+DAAPLPVPRKLSA+DI+   AS PP LGSVWNRAGTWEEKNLNKWA+DRMKELL SV SLEF+SGKAEI DVSKC
Subjt:  MENGAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKER
        VGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHID+PEFSFGELD+LQMEVRLSEEKDLL  DK+QICQDLKRFLQPVR KLLQFE E+KER
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKER

XP_022973883.1 uncharacterized protein LOC111472472 [Cucurbita maxima]

1.2e-92

87.5

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Query:  MENGAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSKC
        MENGAVSS+TQQG+SYTYWVRE R+DAAPLPVPRKLSA+DI+   AS PP LGSVWNRAGTWEEKNLNKWA+DRMK+LL SV SLEF+SGKAEI DVSKC
Subjt:  MENGAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKER
        VGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHID+PEFSFGELD+LQMEVRLSEEKDLL  DK+QICQD KRFLQPVREKLLQFE E+KER
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKER

XP_023520682.1 uncharacterized protein LOC111784085 [Cucurbita pepo subsp. pepo]

1.6e-92

87.5

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Query:  MENGAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSKC
        MENGAVSS+TQQG+SYTYWVRE R+DAAPLPVPRKLSA+DI+   AS PP LGSVWNRAGTWEEKNLNKWA+DRMKELL SV SLEF+ G AEI DVSKC
Subjt:  MENGAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKER
        VGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHID+PEFSFGELD+LQMEVRLSEEKDLL  DK+QICQDLKRFLQP+REKLLQFE EIKER
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKER

XP_038878257.1 uncharacterized protein LOC120070542 [Benincasa hispida]

1.0e-91

88.06

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Query:  MEN-GAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSK
        MEN GAVSS+TQQG+SYTYWVREAR DAAPLPVPRKLSA+DIL   AS PP LGSVWNRAGTWEEKNLNKWA+DRMKELL SVASLEF++GKAEIADVSK
Subjt:  MEN-GAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSK

Query:  CVGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKE
        CVGDAFLVTVRNKKRVGYTYE TLKIKGEWTI+QEKK VKGHID+PEFSFGELD+LQM+VRLSEEKDLL EDK QICQDLKRFLQPVREKLLQFE E+KE
Subjt:  CVGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKE

Query:  R
        R
Subjt:  R

TrEMBL top hits

e value

%identity

Alignment

A0A0A0M014 Aha1_N domain-containing protein

5.0e-92

88.06

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Query:  MEN-GAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSK
        MEN GAVSS+TQQG+SYTYWVRE R DAAPLPVPRKLSA+DIL   AS PP LGSVWNRAGTWEEKNLNKWA+DRMKELL SVASLEF+SGKAEIADVSK
Subjt:  MEN-GAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSK

Query:  CVGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKE
        CVGDAFLVTVRNKKRVGYTYELTLKIKGEWTI+QEKKTVKGHID+PEFSFGELD+LQM+VRLSEE+DLL EDK QICQDLKRFLQPVRE+LLQFE E+KE
Subjt:  CVGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKE

Query:  R
        R
Subjt:  R

A0A1S3B8I3 uncharacterized protein LOC103487198

5.9e-93

89.05

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Query:  MEN-GAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSK
        MEN GAVSS+TQQG+SYTYWVRE R DAAPLPVPRKLSA+DIL   AS PP LGSVWNRAGTWEEKNLNKWATDRMKELL SVASLEF+SGKAEIADVSK
Subjt:  MEN-GAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSK

Query:  CVGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKE
        CVGDAFLVTVRNKKRVGYTYELTLKIKGEWT+KQEKK VKGHID+PEFSFGELD+LQM+VRLSEEKDLL EDK QICQDLKRFLQPVREKLLQFE E+KE
Subjt:  CVGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKE

Query:  R
        R
Subjt:  R

A0A5A7TA05 Chaperone binding ATPase activator

5.9e-93

89.05

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Query:  MEN-GAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSK
        MEN GAVSS+TQQG+SYTYWVRE R DAAPLPVPRKLSA+DIL   AS PP LGSVWNRAGTWEEKNLNKWATDRMKELL SVASLEF+SGKAEIADVSK
Subjt:  MEN-GAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSK

Query:  CVGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKE
        CVGDAFLVTVRNKKRVGYTYELTLKIKGEWT+KQEKK VKGHID+PEFSFGELD+LQM+VRLSEEKDLL EDK QICQDLKRFLQPVREKLLQFE E+KE
Subjt:  CVGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKE

Query:  R
        R
Subjt:  R

A0A6J1F676 uncharacterized protein LOC111441189

5.9e-93

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Query:  MENGAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSKC
        MENGAVSS+TQQG+SYTYWVRE R+DAAPLPVPRKLSA+DI+   AS PP LGSVWNRAGTWEEKNLNKWA+DRMKELL SV SLEF+SGKAEI DVSKC
Subjt:  MENGAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKER
        VGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHID+PEFSFGELD+LQMEVRLSEEKDLL  DK+QICQDLKRFLQPVR KLLQFE E+KER
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKER

A0A6J1IEG5 uncharacterized protein LOC111472472

5.9e-93

87.5

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Query:  MENGAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSKC
        MENGAVSS+TQQG+SYTYWVRE R+DAAPLPVPRKLSA+DI+   AS PP LGSVWNRAGTWEEKNLNKWA+DRMK+LL SV SLEF+SGKAEI DVSKC
Subjt:  MENGAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDIL---ASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSKC

Query:  VGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKER
        VGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHID+PEFSFGELD+LQMEVRLSEEKDLL  DK+QICQD KRFLQPVREKLLQFE E+KER
Subjt:  VGDAFLVTVRNKKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKER

SwissProt top hits

e value

%identity

Alignment

O95433 Activator of 90 kDa heat shock protein ATPase homolog 1

1.4e-06

31.13

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Query:  WEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSKCVGDAFLVTVRNKK-RVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFS-FGELDELQMEV
        W E++ + W+TD++K L  +V  ++   GK E+ +VSK  G+A   ++ N+K ++ + YE ++K+    T K   +  KGH++IP  S    +DE+++ V
Subjt:  WEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSKCVGDAFLVTVRNKK-RVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFS-FGELDELQMEV

Query:  RLSEEK
         L++++
Subjt:  RLSEEK

Arabidopsis top hits

e value

%identity

Alignment

AT5G58110.1 chaperone binding;ATPase activators

3.8e-68

65.61

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Query:  TQQGSSYTYWVREARDDAAPLPVPRKLSANDI-LASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSKCVGDAFLVTVRN
        T++GSSY YWVREA  DAAP P+P+KLS ND+ L + P +LGS+WNRAGTWEEK+L KWATDR+KELL SV SL+F+SGKAEI DV++CVGDAFLVTVRN
Subjt:  TQQGSSYTYWVREARDDAAPLPVPRKLSANDI-LASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSKCVGDAFLVTVRN

Query:  KKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKER
        KKRVGYTYEL+LK++GEW+ ++  K VKG ++IPEFSFGELD+L+++V+LSE+K+L  + K++I  D+K+FL+P+R KL  FE E+K+R
Subjt:  KKRVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKER

Sequences

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CDS sequence

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ATGGAGAATGGAGCAGTTTCTTCCGACACCCAACAGGGCTCCTCTTACACTTACTGGGTCAGGGAAGCGCGGGACGACGCGGCTCCGCTCCCTGTTCCTCGCAAGCTCTC
CGCTAATGACATTCTCGCTTCCCACCCTCCCGCCCTTGGCTCCGTCTGGAATCGGGCTGGAACTTGGGAGGAGAAGAACTTGAATAAATGGGCGACTGATAGAATGAAGG
AATTGCTAAAGTCAGTGGCTTCCTTGGAGTTCGCCAGTGGCAAAGCAGAAATAGCGGATGTATCAAAATGTGTTGGGGATGCTTTTTTGGTGACTGTCCGCAACAAGAAA
CGTGTTGGTTATACATATGAACTCACTTTGAAAATTAAAGGTGAGTGGACTATTAAACAGGAGAAAAAGACGGTGAAAGGGCATATCGACATCCCAGAATTCTCATTTGG
CGAGCTGGATGAGTTGCAGATGGAAGTGAGATTGAGCGAAGAGAAAGATCTACTGGCTGAGGATAAGAAGCAGATTTGCCAAGATTTGAAGCGGTTTTTGCAGCCTGTTC
GTGAAAAGTTGCTTCAATTCGAACTGGAGATCAAAGAAAGATAA

mRNA sequence

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GTTGAATCTCGTGCGAGTCCTTGCGTTGCGCCATTAACACAAAACCTGCAATTCGAAATCTTCTGGAAGCTTCGTCGCAGATCCCCCCTCCCCTTCCTCCCCATCGTCTC
TGACATTCAAATTTGGCGTGCGCAATCTCTTCTCTGATCCTTTGTGCAGGATTGGAAGAAGCGTTTTTCCTTCGTTGTTGGGTTCGCGATGGAGAATGGAGCAGTTTCTT
CCGACACCCAACAGGGCTCCTCTTACACTTACTGGGTCAGGGAAGCGCGGGACGACGCGGCTCCGCTCCCTGTTCCTCGCAAGCTCTCCGCTAATGACATTCTCGCTTCC
CACCCTCCCGCCCTTGGCTCCGTCTGGAATCGGGCTGGAACTTGGGAGGAGAAGAACTTGAATAAATGGGCGACTGATAGAATGAAGGAATTGCTAAAGTCAGTGGCTTC
CTTGGAGTTCGCCAGTGGCAAAGCAGAAATAGCGGATGTATCAAAATGTGTTGGGGATGCTTTTTTGGTGACTGTCCGCAACAAGAAACGTGTTGGTTATACATATGAAC
TCACTTTGAAAATTAAAGGTGAGTGGACTATTAAACAGGAGAAAAAGACGGTGAAAGGGCATATCGACATCCCAGAATTCTCATTTGGCGAGCTGGATGAGTTGCAGATG
GAAGTGAGATTGAGCGAAGAGAAAGATCTACTGGCTGAGGATAAGAAGCAGATTTGCCAAGATTTGAAGCGGTTTTTGCAGCCTGTTCGTGAAAAGTTGCTTCAATTCGA
ACTGGAGATCAAAGAAAGATAAAAGTTTCATTACCCCAACAATAATATGTACCATTTATTTATGATTTGCCAGAATGTCTTATTGGATCAGATCATAAGGGTCTGTGAGA
TGCTAAATTGTAATACAACTGTTGTGGGAATTTGCTAGATTCTTCAATGTTTAAAGTACTTTGAGGTTCTTAGATATGGTAGACTGATTATTTTATCA

Protein sequence

Show/hide protein sequence

MENGAVSSDTQQGSSYTYWVREARDDAAPLPVPRKLSANDILASHPPALGSVWNRAGTWEEKNLNKWATDRMKELLKSVASLEFASGKAEIADVSKCVGDAFLVTVRNKK
RVGYTYELTLKIKGEWTIKQEKKTVKGHIDIPEFSFGELDELQMEVRLSEEKDLLAEDKKQICQDLKRFLQPVREKLLQFELEIKER

Sed0010250 (gene) of Chayote v1 genome