| GenBank top hits | e value | %identity | Alignment |
|---|
| KAG6596930.1 DNA topoisomerase 1 alpha, partial [Cucurbita argyrosperma subsp. sororia] | 0.0e+00 | 75.4 | Show/hide |
Query: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQAS---SPNGQTSNAHKRMTALPNTPPLK-SEIGTEKASNSYIQAPLAKPS
MAVETF K P+FDED D MPIVFKRSS SRQN + SEA R NK SGRQ S SPNGQ+SNA R T+LP T P+K SE+GT+KASNS IQAPL K
Subjt: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQAS---SPNGQTSNAHKRMTALPNTPPLK-SEIGTEKASNSYIQAPLAKPS
Query: TSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGKRHGF
+ L V +S D + KH+ A+VKE++D HP E+SDSEDDKPLS +LK NSNPP +G VPTV KNKV KSSGDSDDEIP S KF MKS S VSGG +HGF
Subjt: TSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGKRHGF
Query: DEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSNSKPT
DEKKPL+SKVH NG TS DKLQKP V+SSKR LPNADS SS QFS KKPKLSDS+TP +KL S+KAKQEVD DDDHIPISQR+K VA S NK +SK T
Subjt: DEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSNSKPT
Query: VSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKEN
VSKV+SSS+KKT+KKSKKPVKKSKYV+S KLLPS+GDGQKKWT+LVHNGVIFPP YQTHGVK+++KGK VDLTPEQEEVATMFAVMKDTDYM KPKFKEN
Subjt: VSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKEN
Query: FWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF------------------
FWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMT + F
Subjt: FWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF------------------
Query: --------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAV
+RWKEVRHDNTVTWLAFWNDPIN KEFKYVFLAASSSLKGQSDKEKYEKAR LKDYIKNIRNAY+K+FTSKDPTRRQIAV
Subjt: --------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAV
Query: ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPG
ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSG+DDLFDKLDTSKLNAHLKDLMPG
Subjt: ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPG
Query: LTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKR
LTAKVFRTYNAS TLDDMLNR TK GDV EKI IYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGK PLKDA+GKQKR
Subjt: LTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKR
Query: NLSPE
NL+PE
Subjt: NLSPE
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| KAG7015549.1 DNA topoisomerase 1 beta [Cucurbita argyrosperma subsp. argyrosperma] | 0.0e+00 | 75.19 | Show/hide |
Query: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANH----RPNKPSGR---QASSPNGQTSNAHKRMTALPNTPPLKSEIGTEKASNSYIQAPLA
MAVETF K P+FD+D D MPIVFKRSS SRQN ++SE H R N+ SGR A S NGQ+SNA KRMT+LP T P++ EIG++KA+ S IQ PL
Subjt: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANH----RPNKPSGR---QASSPNGQTSNAHKRMTALPNTPPLKSEIGTEKASNSYIQAPLA
Query: KPSTSPLIVPNSMDGRPKHVPNAAVKEQNDT-HPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGK
K + L V +SMD RPK + NAA+KE+ND+ HP QENSDSEDDKPLS +LK NSN PS+GP+PTV KNK+ KSS DSDDE+P S KFQMKSASGV GGK
Subjt: KPSTSPLIVPNSMDGRPKHVPNAAVKEQNDT-HPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGK
Query: RHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSN
+HGFDEKKPL SKVH NGSTS DKLQKPAVVSSKR LPNADS SS Q S KKPKLSDS+TP S SLKAKQEV DDDHIPISQR+KM +A+VNKSS
Subjt: RHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSN
Query: SKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPK
SK TVSKV SSSIKKT+KKSKKPVKKSKYV+S KLLPS+GDGQKKWTTLVHNGVIFPP YQTHGVK+L KGK VDLTPEQEEVATMFAVMKDTDYM KPK
Subjt: SKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPK
Query: FKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF--------------
FKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMT + F
Subjt: FKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF--------------
Query: ------------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRR
RWKEVRHDNTVTWLAFWNDPIN KEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRN+Y+K+FTSKDPTRR
Subjt: ------------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRR
Query: QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKD
QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKD
Subjt: QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKD
Query: LMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEG
LMPGLTAKVFRTYNAS TLDDMLNR TK G+V EKI YQHANKEVAIICNHQRTVSKSHGAQM+RLNEKISELRDILKELKIDLDRAKKGK PLK ++G
Subjt: LMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEG
Query: KQKRNLSPEA
KQKRNL+PEA
Subjt: KQKRNLSPEA
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| XP_022940477.1 DNA topoisomerase 1 alpha-like [Cucurbita moschata] | 0.0e+00 | 75.65 | Show/hide |
Query: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQAS---SPNGQTSNAHKRMTALPNTPPLK-SEIGTEKASNSYIQAPLAKPS
MAVETF K P+FDED D MPIVFKRSS SRQN + SEA R NK SGRQ S SPNGQ+SNA R T+LP T P+K SE+GT+KASNS IQAPL K
Subjt: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQAS---SPNGQTSNAHKRMTALPNTPPLK-SEIGTEKASNSYIQAPLAKPS
Query: TSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGKRHGF
+ L V +S D + KH+ AAVKE++D HP E SDSEDDKPLS +LK NSNPP +G VPTV KNKV KSSGDSDD IP S KF MKS S VSGG +HGF
Subjt: TSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGKRHGF
Query: DEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSNSKPT
DEKKPL+SKVH NG TS DKLQKP V+SSKR LPNADS SS QFS KKPKLSDS+TP +KL S+KAKQEVD DDDHIPISQR+K VA S NKS +SK T
Subjt: DEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSNSKPT
Query: VSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKEN
VSKV+SSS+KKT+KKSKKPVKKSKYV+S KLLPS+GDGQKKWT+LVHNGVIFPP YQTHGVKM++KGK VDLTPEQEEVATMFAVMKDTDYM KPKFKEN
Subjt: VSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKEN
Query: FWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF------------------
FWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMT + F
Subjt: FWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF------------------
Query: --------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAV
+RWKEVRHDNTVTWLAFWNDPIN KEFKYVFLAASSSLKGQSDKEKYEKAR LKDYIKNIRNAY+K+FTSKDPTRRQIAV
Subjt: --------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAV
Query: ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPG
ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSG+DDLFDKLDTSKLNAHLKDLMPG
Subjt: ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPG
Query: LTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKR
LTAKVFRTYNAS TLDDMLNR TK GDV EKI IYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGK PLKDA+GKQKR
Subjt: LTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKR
Query: NLSPE
NL+PE
Subjt: NLSPE
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| XP_023520897.1 DNA topoisomerase 1 alpha-like [Cucurbita pepo subsp. pepo] | 0.0e+00 | 75.06 | Show/hide |
Query: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQAS---SPNGQTSNAHKRMTALPNTPPLK-SEIGTEKASNSYIQAPLAKPS
MA+ETF K P+FDED D MPIVFKRSS SRQN + SEA R NK SGRQ S S NGQ+SNA R T+LP T P+K SE+GT+KASNS QAP K
Subjt: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQAS---SPNGQTSNAHKRMTALPNTPPLK-SEIGTEKASNSYIQAPLAKPS
Query: TSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGKRHGF
+ L V +S D + KH+ AAVKE++D HP E+SDSEDDKPLS +LK NSNPP +G VPTV KNKV KSSGDSDDEIP S KF MKS S VSGG +HGF
Subjt: TSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGKRHGF
Query: DEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRI-KMVAASVNKSSNSKP
DEKKPL+SKVH NG TS DKLQKP V+SSKR LPNADS SS QFS KKPKLSDS+TP +KL S+KAKQEVD DDDHIPISQR+ K+VA S NKS +SK
Subjt: DEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRI-KMVAASVNKSSNSKP
Query: TVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKE
TVSKV+SSS+KKT+KKSKKPVKKSKYV+S KLLPS+GDGQKKWT+LVHNGVIFPP YQTHGVKM++KGK VDLTPEQEEVATMFAVMKDTDYM KPKFKE
Subjt: TVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKE
Query: NFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF-----------------
NFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMT + F
Subjt: NFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF-----------------
Query: ---------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIA
+RWKEVRHDNTVTWLAFWNDPIN KEFKYVFLAASSSLKGQSDKEKYEKAR LKDYIKNIRNAY+K+FTSKDPTRRQIA
Subjt: ---------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIA
Query: VATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMP
VATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSG+DDLFDKLDTSKLNAHLKDLMP
Subjt: VATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMP
Query: GLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQK
GLTAKVFRTYNAS TLDDMLNR +K GDV EKI IYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGK PLKDA+GKQK
Subjt: GLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQK
Query: RNLSPE
RNL+PE
Subjt: RNLSPE
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| XP_023553297.1 DNA topoisomerase 1 beta-like [Cucurbita pepo subsp. pepo] | 0.0e+00 | 75.06 | Show/hide |
Query: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANH----RPNKPSGR---QASSPNGQTSNAHKRMTALPNTPPLKSEIGTEKASNSYIQAPLA
MAVETF K P+FD+D D MPIVFKRSS SRQN ++SE H R N+ SGR A S NGQ+SNA KRMT+LP T P++ EIG++KAS S IQ PL
Subjt: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANH----RPNKPSGR---QASSPNGQTSNAHKRMTALPNTPPLKSEIGTEKASNSYIQAPLA
Query: KPSTSPLIVPNSMDGRPKHVPNAAVKEQNDT-HPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGK
K + L V +SMD RPK + NAAVKE+ND+ HP Q+NSDSEDDKPLS +LK NSN PS+GP+PTV KNK+ KSS DSDDE+P S KFQMKSASGV GG+
Subjt: KPSTSPLIVPNSMDGRPKHVPNAAVKEQNDT-HPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGK
Query: RHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSN
+HGFDEKKPL SKVH NGSTS DKLQKPAVVSSKR LPNADS SS Q S KKPKLSDS+TP S SLKAKQEV DDDHIPISQR+KM +A+VNKSS
Subjt: RHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSN
Query: SKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPK
SK TVSKV SSSIKKT+KKSKKPVKKSKYV+S KLLPS+GDGQKKWTTLVHNGVIFPP YQTHGVK+L KGK VDLTPEQEEVATMFAVMKDTDYM KPK
Subjt: SKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPK
Query: FKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF--------------
FKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMT + F
Subjt: FKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF--------------
Query: ------------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRR
RWKEVRHDNTVTWLAFWNDPIN KEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRN+Y+K+FTSKDPTRR
Subjt: ------------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRR
Query: QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKD
QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKD
Subjt: QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKD
Query: LMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEG
LMPGLTAKVFRTYNAS TLDDMLNR TK G+V EKI YQHANKEVAIICNHQRTVSKSHGAQM+RLNEKISELRDI+KELKIDLDRAKKGK PLK ++G
Subjt: LMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEG
Query: KQKRNLSPEA
KQKRNL+PEA
Subjt: KQKRNLSPEA
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| TrEMBL top hits | e value | %identity | Alignment |
|---|
| A0A1S3BM72 DNA topoisomerase I | 0.0e+00 | 74.23 | Show/hide |
Query: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANH----RPNKPSGRQAS---SPNGQTSNAHKRMTALPNTPPLKSEIGTEKA-SNSYIQAPL
MAVETF K P+FD+D D MPIVFKRSS SRQN + SE H R NK GRQ S S NGQ+SN KRMT+LP T P++SEIG++KA +S IQ PL
Subjt: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANH----RPNKPSGRQAS---SPNGQTSNAHKRMTALPNTPPLKSEIGTEKA-SNSYIQAPL
Query: AKPSTSPLIVPNSMDGRPKHVPNAAVKEQN-DTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGG
K L +SMD RPK++ NAAVKE+N +P+QENSDSEDDKPLS +LK NSN P++G V T+PKNKV KSSGDSDDE+P S KFQMK ASG G
Subjt: AKPSTSPLIVPNSMDGRPKHVPNAAVKEQN-DTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGG
Query: KRHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSS
K+ GFDEKKPLV KVH NGSTS DKLQKPAV+SSKR LPN DS S QFS KKPKLSDS++P S+KL SLKAKQEVD DDD IPISQR+K A+VNKSS
Subjt: KRHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSS
Query: NSKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKP
+SKPTVSKV+SSSIKKT KKSKKPVKKSKYV+S KLLPSAGDGQKKWTTLVHNGVIFPP YQTHGVKML+KGK VDLTP+QEEVATMFAVMKDTDYMLKP
Subjt: NSKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKP
Query: KFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF-------------
KFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQ EKEKKKQMT + F
Subjt: KFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF-------------
Query: -------------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTR
+RWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKAR+LKDYIKNIRNAY+K+FTSKDPTR
Subjt: -------------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTR
Query: RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLK
RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSI+YENTVEVELPVFKAITQFQSGKSG+DDLFDKLDT+KLNAHLK
Subjt: RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLK
Query: DLMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAE
DLMPGLTAKVFRTYNAS TLDDMLNR TK G+V EKI YQHANKEVAIICNHQRTVSKSHGAQM+RLNEKISELRDILKELKIDLDRAKKGK PLK ++
Subjt: DLMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAE
Query: GKQKRNLSPEA
GKQKRNL+PEA
Subjt: GKQKRNLSPEA
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| A0A6J1EWI0 DNA topoisomerase I | 0.0e+00 | 75.06 | Show/hide |
Query: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANH----RPNKPSGR---QASSPNGQTSNAHKRMTALPNTPPLKSEIGTEKASNSYIQAPLA
MAVETF K P+FD+D D MPIVFKRSS SRQN ++SE H R N+ SGR A S NGQ+SNA KRMT+LP T P++ EIG++KA+ S IQ PL
Subjt: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANH----RPNKPSGR---QASSPNGQTSNAHKRMTALPNTPPLKSEIGTEKASNSYIQAPLA
Query: KPSTSPLIVPNSMDGRPKHVPNAAVKEQNDT-HPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGK
K + L V +SMD RPK + NAAVKE+ND+ HP QENSDSEDDKPLS +LK NSN PS+GP+PTV KNK+ KSS DSDDE+P S KFQMKSASGV GGK
Subjt: KPSTSPLIVPNSMDGRPKHVPNAAVKEQNDT-HPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGK
Query: RHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSN
+HGF EKKPL SKVH NGSTS DKLQKPAVVSSKR LPNADS SS Q S KKPKLSDS+TP S SLKAKQEV DDDHIPISQR+KM +A+VNKSS
Subjt: RHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSN
Query: SKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPK
SK TVSKV SSSIKKT+KKSKKPVKKSKYV+S KLLPS+GDGQKKWTTLVHNGVIFPP YQTHGVK+L KGK VDLT EQEEVATMFAVMKDTDYM KPK
Subjt: SKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPK
Query: FKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF--------------
FKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMT + F
Subjt: FKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF--------------
Query: ------------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRR
RWKEVRHDNTVTWLAFWNDPIN KEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRN+Y+K+FTSKDPTRR
Subjt: ------------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRR
Query: QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKD
QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKD
Subjt: QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKD
Query: LMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEG
LMPGLTAKVFRTYNAS TLDDMLNR TK G+V EKI YQHANKEVAIICNHQRTVSKSHGAQM+RLNEKISELRDILKELKIDLDRAKKGK PLK ++G
Subjt: LMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEG
Query: KQKRNLSPEA
KQKRNL+PEA
Subjt: KQKRNLSPEA
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| A0A6J1FIM6 DNA topoisomerase I | 0.0e+00 | 75.65 | Show/hide |
Query: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQAS---SPNGQTSNAHKRMTALPNTPPLK-SEIGTEKASNSYIQAPLAKPS
MAVETF K P+FDED D MPIVFKRSS SRQN + SEA R NK SGRQ S SPNGQ+SNA R T+LP T P+K SE+GT+KASNS IQAPL K
Subjt: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQAS---SPNGQTSNAHKRMTALPNTPPLK-SEIGTEKASNSYIQAPLAKPS
Query: TSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGKRHGF
+ L V +S D + KH+ AAVKE++D HP E SDSEDDKPLS +LK NSNPP +G VPTV KNKV KSSGDSDD IP S KF MKS S VSGG +HGF
Subjt: TSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGKRHGF
Query: DEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSNSKPT
DEKKPL+SKVH NG TS DKLQKP V+SSKR LPNADS SS QFS KKPKLSDS+TP +KL S+KAKQEVD DDDHIPISQR+K VA S NKS +SK T
Subjt: DEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSNSKPT
Query: VSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKEN
VSKV+SSS+KKT+KKSKKPVKKSKYV+S KLLPS+GDGQKKWT+LVHNGVIFPP YQTHGVKM++KGK VDLTPEQEEVATMFAVMKDTDYM KPKFKEN
Subjt: VSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKEN
Query: FWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF------------------
FWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMT + F
Subjt: FWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF------------------
Query: --------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAV
+RWKEVRHDNTVTWLAFWNDPIN KEFKYVFLAASSSLKGQSDKEKYEKAR LKDYIKNIRNAY+K+FTSKDPTRRQIAV
Subjt: --------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAV
Query: ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPG
ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSG+DDLFDKLDTSKLNAHLKDLMPG
Subjt: ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPG
Query: LTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKR
LTAKVFRTYNAS TLDDMLNR TK GDV EKI IYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGK PLKDA+GKQKR
Subjt: LTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKR
Query: NLSPE
NL+PE
Subjt: NLSPE
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| A0A6J1KZE0 DNA topoisomerase I | 0.0e+00 | 75.19 | Show/hide |
Query: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANH----RPNKPSGR---QASSPNGQTSNAHKRMTALPNTPPLKSEIGTEKASNSYIQAPLA
MAVETF K +FD+D D MPIVFKRSS SRQN ++SE H R N+ SGR A S NGQ+SNA KRMT+LP T P++ EIG++KAS S IQ PL
Subjt: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANH----RPNKPSGR---QASSPNGQTSNAHKRMTALPNTPPLKSEIGTEKASNSYIQAPLA
Query: KPSTSPLIVPNSMDGRPKHVPNAAVKEQNDT-HPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGK
K + L V +SMD RPK + NAAVKE+ND+ HP QENSDSEDDKPLS +LK NSN PS+GP+PTV KNK+ KSS DSDDE+P S KF+MKSASGV GGK
Subjt: KPSTSPLIVPNSMDGRPKHVPNAAVKEQNDT-HPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGK
Query: RHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSN
+HGFDEKKPL SKVH NGSTS DKLQKPAVVSSKR LPNADS SS Q S KKPKLSDS+TP S SLKAKQEV DDDHIPISQR+KM +A+VNKSS
Subjt: RHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSN
Query: SKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPK
SK TVSKV SSSIKKT+KKSKKPVKKSKYV+S KLLPS+GDGQKKWTTLVHNGVIFPP YQTHGVK+L KGK VDLTPEQEEVATMFAVMKDTDYM KPK
Subjt: SKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPK
Query: FKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF--------------
FKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMT + F
Subjt: FKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF--------------
Query: ------------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRR
RWKEVRHDNTVTWLAFWNDPIN KEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRN+Y+K+FTSKDPTRR
Subjt: ------------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRR
Query: QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKD
QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKD
Subjt: QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKD
Query: LMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEG
LMPGLTAKVFRTYNAS TLDDMLNR TK G+V EKI YQHANKEVAIICNHQRTVSKSHGAQM+RLNEKISELRDILKELKIDLDRAKKGK PLK ++G
Subjt: LMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEG
Query: KQKRNLSPEA
KQKRNL+PEA
Subjt: KQKRNLSPEA
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| A0A6J1L1R3 DNA topoisomerase I | 0.0e+00 | 74.66 | Show/hide |
Query: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQAS---SPNGQTSNAHKRMTALPNTPPLK-SEIGTEKASNSYIQAPLAKPS
MAVETF K P FDED D MPIVFKRSS SRQN + SEA R NK SGRQ S S NGQTSNA R T+LP T P+K S++GT+KASNS IQA L K
Subjt: MAVETFEKTPIFDED--DGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQAS---SPNGQTSNAHKRMTALPNTPPLK-SEIGTEKASNSYIQAPLAKPS
Query: TSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGKRHGF
+ L V +S D + +H+ AAVKE+ND HP E+SDSEDDKPLS +LK SNPP +G VPTV KNKV KSS DSDDEIP S KF MKS+S VSGG +HGF
Subjt: TSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGKRHGF
Query: DEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSNSKPT
DEKKPL+SKVH NG S DKLQKP V+SSKR LPNADS QFS KKPKLSDS+TP +KL S+KAKQEVD +DDHIPISQR+K VA S NKS +SK T
Subjt: DEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSNSKPT
Query: VSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKEN
VSKV+SSS+KKT KKSKKPVKKSKYV+S KLLPS+GDGQKKWT+LVHNGVIFPP YQTHGVKM++KGK VDLTPEQEEVATMFAVMKDTDYM KP+FKEN
Subjt: VSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKEN
Query: FWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF------------------
FWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMT + F
Subjt: FWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-------------------------------------FF------------------
Query: --------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAV
+RWKEVRHDNTVTWLAFWNDPIN KEFKYVFLAASSSLKGQSDKEKYEKAR LKDYIKNIRNAY+K+FTSKDPTRRQIAV
Subjt: --------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAV
Query: ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPG
ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSG+DDLFDKLDTSKLNAHLKDLMPG
Subjt: ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPG
Query: LTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKR
LTAKVFRTYNAS TLDDMLNR TK GDV EKI IYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGK PLKDA+GKQKR
Subjt: LTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKR
Query: NLSPE
NL+PE
Subjt: NLSPE
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| SwissProt top hits | e value | %identity | Alignment |
|---|
| P04786 DNA topoisomerase 1 | 2.0e-87 | 38.39 | Show/hide |
Query: SKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSNSKPTVSKVISS
SKV+H S+ D P + K+ + +S+SLQ +P SD +K + K K E P+ Q + + KS+ SKP K
Subjt: SKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSNSKPTVSKVISS
Query: SIK-KTVKKSKKPVKKSKYVQSIKLLPSAGDGQK--------------KWTTLVHNGVIFPPSYQ--THGVKMLFKGKHVDLTPEQEEVATMFAVMKDTD
+K KT KK ++ +K K + + A + ++ KW TL HNGVIFPP YQ +K+ + GK VDL P+ EEVA FA + ++D
Subjt: SIK-KTVKKSKKPVKKSKYVQSIKLLPSAGDGQK--------------KWTTLVHNGVIFPPSYQ--THGVKMLFKGKHVDLTPEQEEVATMFAVMKDTD
Query: YMLKPKFKENFWNDWRKLLGKNH------VIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-----------------FFD---------------------
+ P F++NF+ND+ ++L ++ I+ CDFT ++D++Q +KE+KKQ+T+Q F +
Subjt: YMLKPKFKENFWNDWRKLLGKNH------VIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ-----------------FFD---------------------
Query: ------------------------------------RWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYS
+W E+RHDNTV WLA W + I FKYV LAA+SSLKGQSD +K+EKAR LK YI IR Y+
Subjt: ------------------------------------RWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYS
Query: KNFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQF-QSGKSGSDDLFDK
+N SK RQ AVA YLID ALRAG EK +DEADTVGCC+L+ E+V PPN + F+FLGKDSI++ VEV+ VFK +T F + K LFD+
Subjt: KNFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQF-QSGKSGSDDLFDK
Query: LDTSKLNAHLKDLMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISEL-----RDILKELKI
LD S LN +L++ MPGLTAKVFRTYNAS T+ D L+ G V EKI Y AN+ VAI+CNHQRTV+K H + + N +I EL R L++
Subjt: LDTSKLNAHLKDLMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISEL-----RDILKELKI
Query: DLDRAKK
D D KK
Subjt: DLDRAKK
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| P30181 DNA topoisomerase 1 alpha | 4.2e-194 | 49.18 | Show/hide |
Query: MAVETFEKTPIF-----DEDDGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQASSPNGQTSNAHKRMTALPN--TPPLKSEIGTEKASNSYIQAPLAKP
M ET K P+ D DD P+ FKR++ N S++N S R + P + S +T+ PN TP K+ I +S + A P
Subjt: MAVETFEKTPIF-----DEDDGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQASSPNGQTSNAHKRMTALPN--TPPLKSEIGTEKASNSYIQAPLAKP
Query: STSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKS-----------SGDSDDEIPQSLKFQMKS
+ SPL + P V + + +++ + E+ DSEDD+PLS L N P S V + K N +SDDE P S F+ K
Subjt: STSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKS-----------SGDSDDEIPQSLKFQMKS
Query: ASGVSGGKRHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLAS----------------LKAKQ---
SG+SGG + DEKKPLV K+H NGST +++ V+ + P +SS+ Q S KK K+S S T K S +KAKQ
Subjt: ASGVSGGKRHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLAS----------------LKAKQ---
Query: ----EVDVDDDHIPISQRIKMVAASVN-------------KSSNSKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIF
D DDD +PIS+R K +++ N SS +KP V+S + K +KK K SKY S K PS+GDGQKKWTTLVHNGVIF
Subjt: ----EVDVDDDHIPISQRIKMVAASVN-------------KSSNSKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIF
Query: PPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ---------
PP Y+ HG+K+L+KGK VDLT EQEEVATMFAVM++TDY KP+F+ENFWNDWR+LLGK HVIQ LDDCDFTPIY+W+ EKEKKKQM+ +
Subjt: PPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ---------
Query: ------------------------------------------------------------------FFDRWKEVRHDNTVTWLAFWNDPINQKEFKYVFL
+RWKEV+HDNTVTWLAFW DPIN KEFKYVFL
Subjt: ------------------------------------------------------------------FFDRWKEVRHDNTVTWLAFWNDPINQKEFKYVFL
Query: AASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSI
A SSLKG SDKEKYEKAR L D+I NIR Y+KNFT+KD RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV+ +PPN ++F+FLGKDSI
Subjt: AASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSI
Query: KYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTV
+Y NTVEVE V+KAI QFQ+GKS +DDLFD+LDTSKLNAHLK+L+PGLTAKVFRTYNAS TLD+ML++ETK GDV +KI +YQ ANKEVAIICNHQRTV
Subjt: KYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTV
Query: SKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKRNLSPEA
SK+HGAQ+ +L +I EL+++LKELK +LDRAKKGK PL+ ++GK+ R+L P A
Subjt: SKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKRNLSPEA
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| P93119 DNA topoisomerase 1 | 3.6e-169 | 51.62 | Show/hide |
Query: HVPNAAVKEQNDTHPNQENSDSEDDKPLSHKL------------KVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGKRHGFDEK
+V +KE+ + N E DS+DDKPLSHKL ++ SN P T PK ++ K +DE+ S + Q+ +G S + DE
Subjt: HVPNAAVKEQNDTHPNQENSDSEDDKPLSHKL------------KVNSNPPSRGPVPTVPKNKVNKSSGDSDDEIPQSLKFQMKSASGVSGGKRHGFDEK
Query: KPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSNSKPTVSK
KPL S++ S+ L K ++ K N+D S S KK KLS+ + P + KL + A+QE DD IS N++ S SK
Subjt: KPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVAASVNKSSNSKPTVSK
Query: VISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWN
V + V S V SK ++ +L +GQ LVHNGVIFPP Y+ HGVKML++ VDLTPEQEEVATMFAVM +T+YM KPKF+ENF +
Subjt: VISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWN
Query: DWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQF-----------------------------------------------------------
DWRK+LG+ H+IQNL+DCDFTPIY+W+Q EKEKKKQM+
Subjt: DWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQF-----------------------------------------------------------
Query: -------------------FDRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIR-NAYSKNFTSKDPTRRQIA
+RWKE+RHDNTVTWLAFWNDPIN KEFKYVFLAASSSLKG+ +EKYEK+R LKDYI+ IR AY+K+F SKD +RQIA
Subjt: -------------------FDRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIR-NAYSKNFTSKDPTRRQIA
Query: VATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMP
VATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV+ PN+L+F+FLGKDSI+Y+N VEVE VF AI QF+SGK G DDLFD+LDTSKLNAHLK+LMP
Subjt: VATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMP
Query: GLTAKVFRTYNASTTLDDM-----LNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDA
GLTAKVFRTYNAS TLD+M L+RETKGGDV EK+ +YQHANKEVAIICNHQRTVSKSH AQM RLNEKI EL+ +LKEL+ DL R KGK PLK++
Subjt: GLTAKVFRTYNASTTLDDM-----LNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDA
Query: EGKQKRNLS
+GK KRNL+
Subjt: EGKQKRNLS
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| Q54RC3 DNA topoisomerase 1 | 5.7e-90 | 32.79 | Show/hide |
Query: KASNSYIQ--APLAKP---STSPLIVPNSMDGRPKHVP----NAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDD
KA N I+ P KP + P N PK P + + + + + ++SDS+ D S +S+ P + P+ +P NK SG
Subjt: KASNSYIQ--APLAKP---STSPLIVPNSMDGRPKHVP----NAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKSSGDSDD
Query: EIPQSLKFQMKSASGVSGGKRHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDD
S K + + + K + KP S + S S D + DSSS +KPK S P + K + K+E
Subjt: EIPQSLKFQMKSASGVSGGKRHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDD
Query: HIPISQRIKMVAASVNKSSNSKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQK-------------KWTTLVHNGVIFPPSYQTHGVKM
P+ + +++ + ++ +KT K K +K K + + +G KWTTL+HNG +FPP+Y HG+K
Subjt: HIPISQRIKMVAASVNKSSNSKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQK-------------KWTTLVHNGVIFPPSYQTHGVKM
Query: LFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLL--GKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQFFD---------------
++ GK V LTP+QEEVAT +A +TD++ K FK+NF+ +++ LL + +++ +D CDF+ I+ +T+KE++K + + D
Subjt: LFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLL--GKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQFFD---------------
Query: ------------------------------------------------------------RWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQ
+WKE+ H+NTVTWLAFW + +N FKYV+LA SS +KGQ
Subjt: ------------------------------------------------------------RWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQ
Query: SDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVE
+D++K+E AR LK+ I +IR Y K+F + +RQ+AVA YLID LALR GNEK +D+ADTVGCC+L+VE++K N + +FLGKDS++Y NTV++
Subjt: SDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVE
Query: LPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTYNASTTLDDMLNR-ETKG-GDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQ
+K + F GK +D LFD L ++LN HLK M GL+AKVFRTYNAS TL L++ +TK + EKI Y N+EVAI+CNHQ+ K+
Subjt: LPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTYNASTTLDDMLNR-ETKG-GDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQ
Query: MSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKR
MS+++EKI ELRD+ DL R K GK P E + R
Subjt: MSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKR
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| Q9FJ79 DNA topoisomerase 1 beta | 6.8e-192 | 49.24 | Show/hide |
Query: MAVETFEKTPI--------FDEDDGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQASSPNGQTSNAHKRMTALPNTPPLKSEI-GTEKASNSYIQAPLA
MA E F K + +++D +P+VFKR+S + + +RP+ + +S G T ++PP++S + ++++S ++ +
Subjt: MAVETFEKTPI--------FDEDDGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQASSPNGQTSNAHKRMTALPNTPPLKSEI-GTEKASNSYIQAPLA
Query: KPS--TSPLIVPNSMDGRPKHVPNAAVKEQN-----DTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPT---VPKNKVNKSS----GDS--------D
KP+ +S + +++ + + KE+N + ++ DSEDDKPLS +LK++S ++ P + + V KS+ G S D
Subjt: KPS--TSPLIVPNSMDGRPKHVPNAAVKEQN-----DTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPT---VPKNKVNKSS----GDS--------D
Query: DEIPQSLKFQMKSASGVSGGKRHGFDEKKPLVSKVHHNG---STSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTP---------------
+ P S Q K++ G S K ++K+PLV+ + NG T Q PA KR P SSS Q S K+PKLS+ P
Subjt: DEIPQSLKFQMKSASGVSGGKRHGFDEKKPLVSKVHHNG---STSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTP---------------
Query: -GSNKLAS--LKA-----KQEVDVDDDHIPISQRIKMVAASVNKSSNSKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNG
G N AS L+A K++ DDH+PI+ R+K +S NKSS++KP+ SK+I+SS + +K K VK SKY +S K LPS GDGQKKW TL HNG
Subjt: -GSNKLAS--LKA-----KQEVDVDDDHIPISQRIKMVAASVNKSSNSKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNG
Query: VIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ------
VIFPP Y+ HGVK+LF+GK VDLTPEQEEVATMFAVM++T+Y KPKF+ENFWNDWRKLLGKNH+I++LDDCDFTPIY+WY EKE KKQMTA+
Subjt: VIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ------
Query: -------------------------------FF--------------------------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKY
F +RWKEV+HDNTVTWLAFW+DPIN KEFKY
Subjt: -------------------------------FF--------------------------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKY
Query: VFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGK
VFLAASSSLKGQSDKEKYEKAR L ++I +IR AY+K+F +KD T+RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV+ +PPN L+F+FLGK
Subjt: VFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGK
Query: DSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQ
DSI+Y NTVEVE V+KAI QFQ+GKS +DDLFD+LDTSKLN HLK+LM GLTAKVFRTYNAS TLD ML++ET+ GDV EK+ +YQ ANKEVAIICNHQ
Subjt: DSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQ
Query: RTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKRNLSPEA
RTVSKSHGAQ+ +L KI ELR+ +KEL IDLDRAKKG+ PL ++GK+KRNL+PEA
Subjt: RTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKRNLSPEA
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| Arabidopsis top hits | e value | %identity | Alignment |
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| AT5G55300.1 DNA topoisomerase I alpha | 3.0e-195 | 49.18 | Show/hide |
Query: MAVETFEKTPIF-----DEDDGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQASSPNGQTSNAHKRMTALPN--TPPLKSEIGTEKASNSYIQAPLAKP
M ET K P+ D DD P+ FKR++ N S++N S R + P + S +T+ PN TP K+ I +S + A P
Subjt: MAVETFEKTPIF-----DEDDGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQASSPNGQTSNAHKRMTALPN--TPPLKSEIGTEKASNSYIQAPLAKP
Query: STSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKS-----------SGDSDDEIPQSLKFQMKS
+ SPL + P V + + +++ + E+ DSEDD+PLS L N P S V + K N +SDDE P S F+ K
Subjt: STSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKS-----------SGDSDDEIPQSLKFQMKS
Query: ASGVSGGKRHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLAS----------------LKAKQ---
SG+SGG + DEKKPLV K+H NGST +++ V+ + P +SS+ Q S KK K+S S T K S +KAKQ
Subjt: ASGVSGGKRHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLAS----------------LKAKQ---
Query: ----EVDVDDDHIPISQRIKMVAASVN-------------KSSNSKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIF
D DDD +PIS+R K +++ N SS +KP V+S + K +KK K SKY S K PS+GDGQKKWTTLVHNGVIF
Subjt: ----EVDVDDDHIPISQRIKMVAASVN-------------KSSNSKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIF
Query: PPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ---------
PP Y+ HG+K+L+KGK VDLT EQEEVATMFAVM++TDY KP+F+ENFWNDWR+LLGK HVIQ LDDCDFTPIY+W+ EKEKKKQM+ +
Subjt: PPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ---------
Query: ------------------------------------------------------------------FFDRWKEVRHDNTVTWLAFWNDPINQKEFKYVFL
+RWKEV+HDNTVTWLAFW DPIN KEFKYVFL
Subjt: ------------------------------------------------------------------FFDRWKEVRHDNTVTWLAFWNDPINQKEFKYVFL
Query: AASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSI
A SSLKG SDKEKYEKAR L D+I NIR Y+KNFT+KD RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV+ +PPN ++F+FLGKDSI
Subjt: AASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSI
Query: KYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTV
+Y NTVEVE V+KAI QFQ+GKS +DDLFD+LDTSKLNAHLK+L+PGLTAKVFRTYNAS TLD+ML++ETK GDV +KI +YQ ANKEVAIICNHQRTV
Subjt: KYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTV
Query: SKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKRNLSPEA
SK+HGAQ+ +L +I EL+++LKELK +LDRAKKGK PL+ ++GK+ R+L P A
Subjt: SKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKRNLSPEA
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| AT5G55300.2 DNA topoisomerase I alpha | 3.0e-195 | 49.18 | Show/hide |
Query: MAVETFEKTPIF-----DEDDGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQASSPNGQTSNAHKRMTALPN--TPPLKSEIGTEKASNSYIQAPLAKP
M ET K P+ D DD P+ FKR++ N S++N S R + P + S +T+ PN TP K+ I +S + A P
Subjt: MAVETFEKTPIF-----DEDDGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQASSPNGQTSNAHKRMTALPN--TPPLKSEIGTEKASNSYIQAPLAKP
Query: STSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKS-----------SGDSDDEIPQSLKFQMKS
+ SPL + P V + + +++ + E+ DSEDD+PLS L N P S V + K N +SDDE P S F+ K
Subjt: STSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKS-----------SGDSDDEIPQSLKFQMKS
Query: ASGVSGGKRHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLAS----------------LKAKQ---
SG+SGG + DEKKPLV K+H NGST +++ V+ + P +SS+ Q S KK K+S S T K S +KAKQ
Subjt: ASGVSGGKRHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLAS----------------LKAKQ---
Query: ----EVDVDDDHIPISQRIKMVAASVN-------------KSSNSKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIF
D DDD +PIS+R K +++ N SS +KP V+S + K +KK K SKY S K PS+GDGQKKWTTLVHNGVIF
Subjt: ----EVDVDDDHIPISQRIKMVAASVN-------------KSSNSKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIF
Query: PPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ---------
PP Y+ HG+K+L+KGK VDLT EQEEVATMFAVM++TDY KP+F+ENFWNDWR+LLGK HVIQ LDDCDFTPIY+W+ EKEKKKQM+ +
Subjt: PPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ---------
Query: ------------------------------------------------------------------FFDRWKEVRHDNTVTWLAFWNDPINQKEFKYVFL
+RWKEV+HDNTVTWLAFW DPIN KEFKYVFL
Subjt: ------------------------------------------------------------------FFDRWKEVRHDNTVTWLAFWNDPINQKEFKYVFL
Query: AASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSI
A SSLKG SDKEKYEKAR L D+I NIR Y+KNFT+KD RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV+ +PPN ++F+FLGKDSI
Subjt: AASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSI
Query: KYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTV
+Y NTVEVE V+KAI QFQ+GKS +DDLFD+LDTSKLNAHLK+L+PGLTAKVFRTYNAS TLD+ML++ETK GDV +KI +YQ ANKEVAIICNHQRTV
Subjt: KYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTV
Query: SKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKRNLSPEA
SK+HGAQ+ +L +I EL+++LKELK +LDRAKKGK PL+ ++GK+ R+L P A
Subjt: SKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKRNLSPEA
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| AT5G55300.3 DNA topoisomerase I alpha | 7.9e-71 | 32.71 | Show/hide |
Query: MAVETFEKTPIF-----DEDDGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQASSPNGQTSNAHKRMTALPN--TPPLKSEIGTEKASNSYIQAPLAKP
M ET K P+ D DD P+ FKR++ N S++N S R + P + S +T+ PN TP K+ I +S + A P
Subjt: MAVETFEKTPIF-----DEDDGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQASSPNGQTSNAHKRMTALPN--TPPLKSEIGTEKASNSYIQAPLAKP
Query: STSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKS-----------SGDSDDEIPQSLKFQMKS
+ SPL + P V + + +++ + E+ DSEDD+PLS L N P S V + K N +SDDE P S F+ K
Subjt: STSPLIVPNSMDGRPKHVPNAAVKEQNDTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPTVPKNKVNKS-----------SGDSDDEIPQSLKFQMKS
Query: ASGVSGGKRHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVA
SG+SGG + DEKKPLV K+H NGST +++ V+ + P +SS+ Q S KK K+S S T S+K KQ+
Subjt: ASGVSGGKRHGFDEKKPLVSKVHHNGSTSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTPGSNKLASLKAKQEVDVDDDHIPISQRIKMVA
Query: ASVNKSSNSKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKD
S+KK + KG+
Subjt: ASVNKSSNSKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNGVIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKD
Query: TDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQFFDRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSD
++ PK K KQ++ R D G D
Subjt: TDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQFFDRWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSD
Query: KEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELP
+ ++ DDDEADTVGCCTLKV NV+ +PPN ++F+FLGKDSI+Y NTVEVE
Subjt: KEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELP
Query: VFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRL
V+KAI QFQ+GKS +DDLFD+LDTSKLNAHLK+L+PGLTAKVFRTYNAS TLD+ML++ETK GDV +KI +YQ ANKEVAIICNHQRTVSK+HGAQ+ +L
Subjt: VFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQRTVSKSHGAQMSRL
Query: NEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKRNLSPEA
+I EL+++LKELK +LDRAKKGK PL+ ++GK+ R+L P A
Subjt: NEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKRNLSPEA
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| AT5G55310.1 DNA topoisomerase 1 beta | 4.8e-193 | 49.24 | Show/hide |
Query: MAVETFEKTPI--------FDEDDGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQASSPNGQTSNAHKRMTALPNTPPLKSEI-GTEKASNSYIQAPLA
MA E F K + +++D +P+VFKR+S + + +RP+ + +S G T ++PP++S + ++++S ++ +
Subjt: MAVETFEKTPI--------FDEDDGMPIVFKRSSGSRQNLIHSEANHRPNKPSGRQASSPNGQTSNAHKRMTALPNTPPLKSEI-GTEKASNSYIQAPLA
Query: KPS--TSPLIVPNSMDGRPKHVPNAAVKEQN-----DTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPT---VPKNKVNKSS----GDS--------D
KP+ +S + +++ + + KE+N + ++ DSEDDKPLS +LK++S ++ P + + V KS+ G S D
Subjt: KPS--TSPLIVPNSMDGRPKHVPNAAVKEQN-----DTHPNQENSDSEDDKPLSHKLKVNSNPPSRGPVPT---VPKNKVNKSS----GDS--------D
Query: DEIPQSLKFQMKSASGVSGGKRHGFDEKKPLVSKVHHNG---STSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTP---------------
+ P S Q K++ G S K ++K+PLV+ + NG T Q PA KR P SSS Q S K+PKLS+ P
Subjt: DEIPQSLKFQMKSASGVSGGKRHGFDEKKPLVSKVHHNG---STSMDKLQKPAVVSSKRSLPNADSSSSLQFSPKKPKLSDSTTP---------------
Query: -GSNKLAS--LKA-----KQEVDVDDDHIPISQRIKMVAASVNKSSNSKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNG
G N AS L+A K++ DDH+PI+ R+K +S NKSS++KP+ SK+I+SS + +K K VK SKY +S K LPS GDGQKKW TL HNG
Subjt: -GSNKLAS--LKA-----KQEVDVDDDHIPISQRIKMVAASVNKSSNSKPTVSKVISSSIKKTVKKSKKPVKKSKYVQSIKLLPSAGDGQKKWTTLVHNG
Query: VIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ------
VIFPP Y+ HGVK+LF+GK VDLTPEQEEVATMFAVM++T+Y KPKF+ENFWNDWRKLLGKNH+I++LDDCDFTPIY+WY EKE KKQMTA+
Subjt: VIFPPSYQTHGVKMLFKGKHVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAQ------
Query: -------------------------------FF--------------------------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKY
F +RWKEV+HDNTVTWLAFW+DPIN KEFKY
Subjt: -------------------------------FF--------------------------------------DRWKEVRHDNTVTWLAFWNDPINQKEFKY
Query: VFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGK
VFLAASSSLKGQSDKEKYEKAR L ++I +IR AY+K+F +KD T+RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV+ +PPN L+F+FLGK
Subjt: VFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYSKNFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGK
Query: DSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQ
DSI+Y NTVEVE V+KAI QFQ+GKS +DDLFD+LDTSKLN HLK+LM GLTAKVFRTYNAS TLD ML++ET+ GDV EK+ +YQ ANKEVAIICNHQ
Subjt: DSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTYNASTTLDDMLNRETKGGDVVEKIAIYQHANKEVAIICNHQ
Query: RTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKRNLSPEA
RTVSKSHGAQ+ +L KI ELR+ +KEL IDLDRAKKG+ PL ++GK+KRNL+PEA
Subjt: RTVSKSHGAQMSRLNEKISELRDILKELKIDLDRAKKGKAPLKDAEGKQKRNLSPEA
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