| GenBank top hits | e value | %identity | Alignment |
|---|
| KAG6581568.1 DNA topoisomerase 2, partial [Cucurbita argyrosperma subsp. sororia] | 2.1e-256 | 75.79 | Show/hide |
Query: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
MADL+RSIPSMVDGLK RKILFC+FKRNFIKEAKVSQF+GYVSEHSAYHHGE SL +I+ MAQDFVGSNN+NLLLPNGQFGTRNHGG DHAS RYI+
Subjt: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
Query: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
TKLSN TRFLFPKDD+KLLNYLN+DGQSIEPTWY+P+IP VLVNG +GIGTGWSS +PNYNPRDIIRNVR ML GE M PMDPWYRGF GTIEKT TK
Subjt: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
Query: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
++YT SGIIE+VSDT LRITELP+R WTN YK+ LDS TRV++KNDK+KEKA KDPFIEQ DHHSDDK +SIDVHLTEEN+ILA+QEGLK+KF
Subjt: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
Query: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
KLTTT+STSNMHLFDANGV+KKY+TPEQILEEFFP+RLEF+EKRKRNLLENLE ELL+LENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKK
Subjt: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
Query: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
KSVE EVAGASNET+E+ E VKGER KVQELCNERDK KGEVE+LRK TPKSLWLKDLD LEKELDEMD+NDAQA+EVR+
Subjt: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
Query: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
QQRI NN++K KISRNAPK PRNSKKT+ S+ + ESMD TTSSSTTTEVA+N VVKPKGKAAPRKAPAKK QGKA
Subjt: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
Query: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
+DDD DDDEVLELK RLAAYK++SSP+ SE
Subjt: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
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| KAG7018075.1 DNA topoisomerase 2 [Cucurbita argyrosperma subsp. argyrosperma] | 1.9e-257 | 75.95 | Show/hide |
Query: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
MADL+RSIPSMVDGLK RKILFC+FKRNFIKEAKVSQF+GYVSEHSAYHHGE SL +I+ MAQDFVGSNN+NLLLPNGQFGTRNHGG DHAS RYI+
Subjt: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
Query: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
TKLSN TRFLFPKDD+KLLNYLN+DGQSIEPTWY+P+IP VLVNG +GIGTGWSS +PNYNPRDIIRNVR ML GE M PMDPWYRGF GTIEKT TK
Subjt: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
Query: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
++YT SGIIE+VSDT LRITELP+R WTN YK+ LDS TRV++KNDK+KEKA KDPFIEQ DHHSDDK +SIDVHLTEEN+ILA+QEGLK+KF
Subjt: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
Query: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
KLTTT+STSNMHLFDANGV+KKY+TPEQILEEFFP+RLEF+EKRKRNLLENLE ELL+LENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKK
Subjt: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
Query: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
KSVE EVAGASNET+E+ E VKGER KVQELCNERDK KGEVE+LRK TPKSLWLKDLD LEKELDEMD+NDAQA+EVR+
Subjt: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
Query: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
QQRI NN++K KISRNAPK PRNSKKT+ S+ + ESMD TTSSSTTTEVA+N VVKPKGKAAPRKAPAKK QGKA
Subjt: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
Query: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
+DDD DDDEVLELKDRLAAYK++SSP+ SE
Subjt: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
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| XP_022935015.1 DNA topoisomerase 2 isoform X1 [Cucurbita moschata] | 5.5e-257 | 75.79 | Show/hide |
Query: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
MADL+RSIPSMVDGLK RKILFC+FKRNFIKEAKVSQF+GYVSEHSAYHHGE SL +I+ MAQDFVGSNN+NLLLPNGQFGTRNHGG DHAS RYI+
Subjt: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
Query: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
TKLSN TRFLFPKDD+KLLNYLN+DGQSIEPTWY+P+IP VLVNG +GIGTGWSS +PNYNPRDIIRNVR ML GE M PMDPWYRGF GTIEKT TK
Subjt: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
Query: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
++YT SGIIE+VSDT LRITELP+R WTN YK+ LDS TRV++KNDK+KEKA KDPFIEQ DHHSDDK +SIDVHLTEEN+ILA+QEGLK+KF
Subjt: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
Query: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
KLTTT+STSNMHLFDANGV+KKY+TPEQILEEFFP+RLEF+EKRKRNLLENLE ELL+LENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKK
Subjt: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
Query: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
KSVE EVAGASNET+E+ E VKGER KVQELCNERDK KGEVE+LRK TPKSLWLKDLD LEKELDEMD+NDAQA+EVR+
Subjt: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
Query: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
QQRI NN++K KISRNAPK PRNSKKT+ S+ + ESMD TTSSSTTTEVA+N VVKPKGKAAPRKAPAKK QGK
Subjt: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
Query: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
+DDD DDDEVLELKDRLAAYK++SSP+ SE
Subjt: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
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| XP_023527820.1 DNA topoisomerase 2 isoform X1 [Cucurbita pepo subsp. pepo] | 1.5e-257 | 76.11 | Show/hide |
Query: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
MADL+RSIPSMVDGLK RKILFC+FKRNFIKEAKVSQF+GYVSEHSAYHHGE SL +I+ MAQDFVGSNN+NLLLPNGQFGTRNHGG DHAS RYI+
Subjt: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
Query: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
TKLSN TRFLFPKDD+KLLNYLN+DGQSIEPTWY+P+IP VLVNG +GIGTGWSS +PNYNPRDIIRNVR ML GE M PMDPWYRGF GTIEKT TK
Subjt: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
Query: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
++YT SGIIE+VSDT LRITELP+R WTN YK+ LDS TRV++KNDK+KEKA KDPFIEQ DHHSDDK +SIDVHLTEEN+ILA+QEGLK+KF
Subjt: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
Query: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
KLTTT+STSNMHLFDANGV+KKY+TPEQILEEFFP+RLEF+EKRKRNLLENLE ELL+LENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKK
Subjt: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
Query: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
KSVE EVAGASNET+E+ E VKGER KVQELCNERDK KGEVE+LRK TPKSLWLKDLD LEKELDEMD+NDAQA+EVR+
Subjt: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
Query: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
QQRI NN+VK KISRNAPK PRNSKKT+ S+ + ESMD TTSSSTTTEVA+N VVKPKGKAAPRKAPAKK QGKA
Subjt: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
Query: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
+DDD DDDEVLELKDRLAAYK++SSP+ SE
Subjt: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
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| XP_023527823.1 DNA topoisomerase 2 isoform X3 [Cucurbita pepo subsp. pepo] | 7.2e-257 | 75.95 | Show/hide |
Query: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
MADL+RSIPSMVDGLK RKILFC+FKRNFIKEAKVSQF+GYVSEHSAYHHGE SL +I+ MAQDFVGSNN+NLLLPNGQFGTRNHGG DHAS RYI+
Subjt: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
Query: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
TKLSN TRFLFPKDD+KLLNYLN+DGQSIEPTWY+P+IP VLVNG +GIGTGWSS +PNYNPRDIIRNVR ML GE M PMDPWYRGF GTIEKT TK
Subjt: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
Query: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
++YT SGIIE+VSDT LRITELP+R WTN YK+ LDS TRV++KNDK+KEKA KDPFIEQ DHHSDDK +SIDVHLTEEN+ILA+QEGLK+KF
Subjt: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
Query: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
KLTTT+STSNMHLFDANGV+KKY+TPEQILEEFFP+RLEF+EKRKRNLLENLE ELL+LENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKK
Subjt: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
Query: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
KSVE EVAGASNET+E+ E VKGER KVQELCNERDK KGEVE+LRK TPKSLWLKDLD LEKELDEMD+NDAQA+EVR+
Subjt: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
Query: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
QQRI NN+VK KISRNAPK PRNSKKT+ S+ + ESMD TTSSSTTTEVA+N VVKPKGKAAPRKAPAKK GKA
Subjt: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
Query: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
+DDD DDDEVLELKDRLAAYK++SSP+ SE
Subjt: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
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| TrEMBL top hits | e value | %identity | Alignment |
|---|
| A0A6J1DGT3 DNA topoisomerase 2 | 2.1e-254 | 75.75 | Show/hide |
Query: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
MADL+RSIPS+VDGLK RKILFC+FKRNFIKEAKVSQF+GYVSEHSAYHHGE SL +I+ MAQDFVGSNN+NLLLPNGQFGTRNHGG DHAS RYI+
Subjt: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
Query: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
TKLSNVTRFLFP+DD++LLNYLN+DGQSIEPTWY+P+IP VLVNG +GIGTGWSS VPNYNPRDII NV+ +L GETM PMDPWY+GF G IEKT TK
Subjt: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
Query: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
+YT SGIIE+VSDT LRITELP+R WTN YK LDS TRVA+KND KEKA KDPFIEQ DHHSDDK +SIDVHLTEEN+ILA+QEGLK+KF
Subjt: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
Query: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
KLTTT+STSNMHLFD+NGV+KKY+TPEQILEEFFP+RLE+YEKRK NLLENLE ELL+LENKVRFILAVVNGEI+VSNRRRVDLFHELQAKGFTPFPKK
Subjt: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
Query: KSVELEVAGASNET---EESSEVKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRRQ
KSVE EVAGASNET EES E KGER KVQELCN+RD+LKGEVEDLRK TPKSLWLKDLD LEKELDEMD+NDAQAEEVR+Q
Subjt: KSVELEVAGASNET---EESSEVKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRRQ
Query: QRITSNNEVKQKISRN-APKTPRNSKKTTISDPVAESMDTTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAVA
QRI +NN+VK KISRN APK PRNSKKT S+ +AESMDTTSSSTT EVASN VVKPKGKAAPRKAPAKK GK V
Subjt: QRITSNNEVKQKISRN-APKTPRNSKKTTISDPVAESMDTTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAVA
Query: VDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
+DD DDDEVLELKDRLAAYKIDSSPD+SE
Subjt: VDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
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| A0A6J1F3D6 DNA topoisomerase 2 | 1.3e-256 | 75.63 | Show/hide |
Query: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
MADL+RSIPSMVDGLK RKILFC+FKRNFIKEAKVSQF+GYVSEHSAYHHGE SL +I+ MAQDFVGSNN+NLLLPNGQFGTRNHGG DHAS RYI+
Subjt: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
Query: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
TKLSN TRFLFPKDD+KLLNYLN+DGQSIEPTWY+P+IP VLVNG +GIGTGWSS +PNYNPRDIIRNVR ML GE M PMDPWYRGF GTIEKT TK
Subjt: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
Query: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
++YT SGIIE+VSDT LRITELP+R WTN YK+ LDS TRV++KNDK+KEKA KDPFIEQ DHHSDDK +SIDVHLTEEN+ILA+QEGLK+KF
Subjt: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
Query: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
KLTTT+STSNMHLFDANGV+KKY+TPEQILEEFFP+RLEF+EKRKRNLLENLE ELL+LENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKK
Subjt: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
Query: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
KSVE EVAGASNET+E+ E VKGER KVQELCNERDK KGEVE+LRK TPKSLWLKDLD LEKELDEMD+NDAQA+EVR+
Subjt: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
Query: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
QQRI NN++K KISRNAPK PRNSKKT+ S+ + ESMD TTSSSTTTEVA+N VVKPKGKAAPRKAPAKK GK
Subjt: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
Query: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
+DDD DDDEVLELKDRLAAYK++SSP+ SE
Subjt: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
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| A0A6J1F9E0 DNA topoisomerase 2 | 2.7e-257 | 75.79 | Show/hide |
Query: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
MADL+RSIPSMVDGLK RKILFC+FKRNFIKEAKVSQF+GYVSEHSAYHHGE SL +I+ MAQDFVGSNN+NLLLPNGQFGTRNHGG DHAS RYI+
Subjt: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
Query: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
TKLSN TRFLFPKDD+KLLNYLN+DGQSIEPTWY+P+IP VLVNG +GIGTGWSS +PNYNPRDIIRNVR ML GE M PMDPWYRGF GTIEKT TK
Subjt: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
Query: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
++YT SGIIE+VSDT LRITELP+R WTN YK+ LDS TRV++KNDK+KEKA KDPFIEQ DHHSDDK +SIDVHLTEEN+ILA+QEGLK+KF
Subjt: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
Query: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
KLTTT+STSNMHLFDANGV+KKY+TPEQILEEFFP+RLEF+EKRKRNLLENLE ELL+LENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKK
Subjt: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
Query: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
KSVE EVAGASNET+E+ E VKGER KVQELCNERDK KGEVE+LRK TPKSLWLKDLD LEKELDEMD+NDAQA+EVR+
Subjt: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
Query: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
QQRI NN++K KISRNAPK PRNSKKT+ S+ + ESMD TTSSSTTTEVA+N VVKPKGKAAPRKAPAKK QGK
Subjt: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
Query: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
+DDD DDDEVLELKDRLAAYK++SSP+ SE
Subjt: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
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| A0A6J1IWX9 DNA topoisomerase 2 | 1.3e-256 | 75.63 | Show/hide |
Query: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
MADL+RSIPSMVDGLK RKILFC+FKRNFIKEAKVSQF+GYVSEHSAYHHGE SL +I+ MAQDFVGSNN+NLLLPNGQFGTRNHGG DHAS RYI+
Subjt: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
Query: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
TKLSN TRFLFPKDD+KLLNYLN+DGQSIEPTWY+P+IP VLVNG +GIGTGWSS +PNYNPRDIIRNVR ML GE M PMDPWYRGF GTIEKT TK
Subjt: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
Query: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
++YT SGIIE+VSDT LRITELP+R WTN YK+ LDS TRV++KNDK+KEKA KDPFIEQ DHHSDDK +SI+VHLTEEN+ILA+QEGLK+KF
Subjt: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
Query: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
KLTTT+STSNMHLFDANGV+KKY+TPEQILEEFFP+RLEF+EKRKRNLLENLE ELL+LENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKK
Subjt: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
Query: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
KSVE EVAGASNET+E+ E VKGER KVQELCNERDK KGEVE+LRK TPKSLWLKDLD LEKELDEMD+NDAQA+EVR+
Subjt: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
Query: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
QQRI NN++K KISRNAPK PRNSKKT+ S+ + ESMD TSSSTTTEVA+N VVKPKGKAAPRKAPAKK QGKA
Subjt: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
Query: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
+DDDG DDEVLELKDRLAAYK++SSP+ SE
Subjt: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
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| A0A6J1J555 DNA topoisomerase 2 | 6.6e-256 | 75.47 | Show/hide |
Query: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
MADL+RSIPSMVDGLK RKILFC+FKRNFIKEAKVSQF+GYVSEHSAYHHGE SL +I+ MAQDFVGSNN+NLLLPNGQFGTRNHGG DHAS RYI+
Subjt: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
Query: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
TKLSN TRFLFPKDD+KLLNYLN+DGQSIEPTWY+P+IP VLVNG +GIGTGWSS +PNYNPRDIIRNVR ML GE M PMDPWYRGF GTIEKT TK
Subjt: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
Query: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
++YT SGIIE+VSDT LRITELP+R WTN YK+ LDS TRV++KNDK+KEKA KDPFIEQ DHHSDDK +SI+VHLTEEN+ILA+QEGLK+KF
Subjt: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
Query: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
KLTTT+STSNMHLFDANGV+KKY+TPEQILEEFFP+RLEF+EKRKRNLLENLE ELL+LENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKK
Subjt: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
Query: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
KSVE EVAGASNET+E+ E VKGER KVQELCNERDK KGEVE+LRK TPKSLWLKDLD LEKELDEMD+NDAQA+EVR+
Subjt: KSVELEVAGASNETEESSE----VKGER------------------KVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRR
Query: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
QQRI NN++K KISRNAPK PRNSKKT+ S+ + ESMD TSSSTTTEVA+N VVKPKGKAAPRKAPAKK GKA
Subjt: QQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMD-TTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAV
Query: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
+DDDG DDEVLELKDRLAAYK++SSP+ SE
Subjt: AVDDDGEDDDEVLELKDRLAAYKIDSSPDQSE
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| SwissProt top hits | e value | %identity | Alignment |
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| O24308 DNA topoisomerase 2 | 5.6e-135 | 46.45 | Show/hide |
Query: RKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIFTKLSNVTRFLFPKDDEKLL
R LF +FK+ KE KV+QF GYVSEHSAYHHGE SL +I+ MAQDFVGSNN+NLL PNGQFGT N GG DHAS RYI+T+LS VTR LF + D+KLL
Subjt: RKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIFTKLSNVTRFLFPKDDEKLL
Query: NYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTEASNYTTSGIIEQVSDTMLR
YLN+DG+SIEP WY+P+IP+VLVNG +GIGTGWSS +PNYNPR+II NVR +L GE + PMDPWY+GF GTIEK+ + Y +G + ++ + R
Subjt: NYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTEASNYTTSGIIEQVSDTMLR
Query: ITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKFKLTTTISTSNMHLFDANGV
ITELPIR WT YK L+S T A KDP IE + DD + I++ + E + +QEGL +KFKLT+TISTSNMHLFDA G
Subjt: ITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKFKLTTTISTSNMHLFDANGV
Query: LKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKLKSVELEVAGASNETEESSE
KK++TPEQILEEFFP+RL++YEK K +L NL LL L+NKVRFIL VVNGEIIVSNR++ +L EL+ KGFTP P+K KS + +VAGA+++ E E
Subjt: LKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKLKSVELEVAGASNETEESSE
Query: ------------VKGE------------------RKVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRRQQRITSNNEVK
V+G VQ+L +E+ + + E E L SLWLKDLD EK+LDE+D A+ + R Q N
Subjt: ------------VKGE------------------RKVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAEEVRRQQRITSNNEVK
Query: QKISRNAPKTPRNSKKTTISDPVAESMDTTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAVAVDDDGEDDDEV
K ++ P+ +N+KK +P ++ + V KPKG+AAP+K K E +D++
Subjt: QKISRNAPKTPRNSKKTTISDPVAESMDTTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAVAVDDDGEDDDEV
Query: LELKDRLAAYKIDSSPDQSE
L++RLAAY I+SS ++S+
Subjt: LELKDRLAAYKIDSSPDQSE
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| O42130 DNA topoisomerase 2-alpha | 3.5e-97 | 42.48 | Show/hide |
Query: ADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIFT
+D RSIPS+VDGLK RK+LF FKRN +E K +Q AG V+E S+YHHGE SL +I+ +AQ+FVGSNNLNLL P GQFGTR HGG D AS RYIFT
Subjt: ADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIFT
Query: KLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTEA
LS + R LFP D+ +L +L DD Q +EP WY+P+IPMVL+NG +GIGTGWS +PN++ R+ + N+RC+L G+ PM P Y+ F GTI+ +
Subjt: KLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTEA
Query: SNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKFK
+ Y SG + + T + ITELP+R WT K + L+ N EK P I + D + V ++EE + A GL + FK
Subjt: SNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKFK
Query: LTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFP----
L T ++ ++M LFD G LKKYE+P+ IL+EFF +RL +Y RK L+ L E +L N+ RFIL ++G+I++ N+ + +L L +G+ P
Subjt: LTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFP----
Query: KKLKSVELEVAGASNETEESSEVKG---------------ERKVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAE
K+L++ E E S EES+ G + K ELC +RD E+EDL+ ++P LW +DL A +ELD ++ Q E
Subjt: KKLKSVELEVAGASNETEESSEVKG---------------ERKVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQAE
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| P08096 DNA topoisomerase 2 | 3.4e-108 | 41.33 | Show/hide |
Query: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
MAD RSIPS+VDGLK RK+++ FKRN + E KVS+ AGYV+ +AYHHGE S+ ++I+ +AQ+FVGSNN+NLL+PNGQFGTR+ GG + ++ RY+
Subjt: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
Query: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
T LS + R LF +D++LLNY ND+GQ IEP +Y+P++PMVLVNG +GIGTGWS+ +PNYNP+DI N+R ML GE + M PWYRGF G+I TK
Subjt: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
Query: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTL--GYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKE
Y SGII Q+ + + ITELPIR WT K L G T EK K FI + H + N+ +V LTE + A+ E L+
Subjt: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTL--GYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKE
Query: KFKLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPF--
KFKL+ T +TSNM FDA+G +KKY++ E IL EF+ +RL Y++RK +++ LE R N+ RFI ++ GE++VS +++ DL EL+ K F P
Subjt: KFKLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPF--
Query: PKKLKSVELEVAGASNETEESSEVKGE-------------------RKVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALE----KELDEMDKNDAQA
PKK V+LEV A E E+S +V + + EL ++D++ E++ L K+TPK LWL DLDA E K +D++ +
Subjt: PKKLKSVELEVAGASNETEESSEVKGE-------------------RKVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALE----KELDEMDKNDAQA
Query: EEVRRQQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMDTTSSSTTTEVASNVVVKPKGKAAPRKA
EE + + + + K + + PR ++ S V + + S +TT +++ P K+
Subjt: EEVRRQQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMDTTSSSTTTEVASNVVVKPKGKAAPRKA
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| P30182 DNA topoisomerase 2 | 1.5e-159 | 51.17 | Show/hide |
Query: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
MADL+RSIPSMVDGLK RKILF AFK+ KE KV+Q GYVS SAYHHGE SL +I+ MAQD+VGSNN+NLLLPNGQFGTR GG D AS RYIF
Subjt: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
Query: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
TKLS VTR LFPKDD+ LL+YLN+DGQ IEPTWY+P+IP VLVNG +GIGTGWS+ +PNYNPR+I+ NVR +L GE+M PMDPWYRGF GTIEKT +K
Subjt: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTTTKTE
Query: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
YT +G+ E+V +T +RITELPIR W + YKN L S K D PF + V ++D+K++ D+ L+EEN++ A QEG +KF
Subjt: ASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKEKATKDPFIEQVDHHSDDKNISIDVHLTEENVILAIQEGLKEKF
Query: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
KLTTTI+TSNMHLFD GV+KKY TPEQILEEFF +R E+YEKRK +++N+E+ELL+LENK RFILAV++GEIIV+ R++ D+ +L+ KGFTPFP+K
Subjt: KLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKL
Query: KSVELEVAG-----ASNETEE--------SSEVKGE---------------RKVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQ
+SVE +AG A+ E EE SS + G KV+EL +RDK+ V D++K TPKSLWL DL++L+KEL+++D DAQ
Subjt: KSVELEVAG-----ASNETEE--------SSEVKGE---------------RKVQELCNERDKLKGEVEDLRKETPKSLWLKDLDALEKELDEMDKNDAQ
Query: AEEV--RRQQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMDTTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFI--
++ Q++I + + K+ R APK P KKTT +E+ + + S+ T+ VVKPK + +K ++ + + S+M T + +
Subjt: AEEV--RRQQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMDTTSSSTTTEVASNVVVKPKGKAAPRKAPAKKLSFKTPPSSMITWKSYDCFI--
Query: MGQQQGKAVAVDDDGE-DDDEVLELKDRLAAYKIDSSPDQS
G+Q K A E ++DE+L+L RLA Y S+P S
Subjt: MGQQQGKAVAVDDDGE-DDDEVLELKDRLAAYKIDSSPDQS
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| Q55BP5 Probable DNA topoisomerase 2 | 6.4e-99 | 36.62 | Show/hide |
Query: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
+AD RSIP++VDGLKT+HRK L+ FKRN KE KV+Q GYVSEHSAYHHGE SL+ +I+ MAQ+FVGSNN+NLL P G +GTR GG D +S RYI
Subjt: MADLRRSIPSMVDGLKTTHRKILFCAFKRNFIKEAKVSQFAGYVSEHSAYHHGETSLHESILKMAQDFVGSNNLNLLLPNGQFGTRNHGGADHASFRYIF
Query: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTT-TKT
T+L+++ R ++ DD+ +L+ + DDG+ ++P +YIPVIPM+LVNGC GIGTGWSS +PNYNPRD+I+N+R + G+ + P+ PWYRGFLG+IE +K
Subjt: TKLSNVTRFLFPKDDEKLLNYLNDDGQSIEPTWYIPVIPMVLVNGCDGIGTGWSSNVPNYNPRDIIRNVRCMLGGETMFPMDPWYRGFLGTIEKTT-TKT
Query: EASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKE---------KATKDPFIEQVDHHSDDKNIS------------
+ Y + GI +++SD ITELPI WT + L T TR K +KEK+ K T ++VD D++ ++
Subjt: EASNYTTSGIIEQVSDTMLRITELPIRLWTNGNKNTLGYKNTLDSFTRVASKNDKEKE---------KATKDPFIEQVDHHSDDKNIS------------
Query: -IDVHLTEENVILAIQEGLKEKFKLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVS
+H + + + +++ FKL +TI+ +NM +FD G ++++ T + E FFP+R++ Y+ RK L E L E RL NK RFILAVVN E+++S
Subjt: -IDVHLTEENVILAIQEGLKEKFKLTTTISTSNMHLFDANGVLKKYETPEQILEEFFPIRLEFYEKRKRNLLENLEMELLRLENKVRFILAVVNGEIIVS
Query: NRRRVDLFHELQAKGF-------------TPFPKKLKSVELEVAGASN-------ETEESSEVKGE-------------RKVQELCNERDKLKGEVEDLR
N ++VDL ++L+ F KK + + E A S+ + E+ + KG +V++L ERD K E + L
Subjt: NRRRVDLFHELQAKGF-------------TPFPKKLKSVELEVAGASN-------ETEESSEVKGE-------------RKVQELCNERDKLKGEVEDLR
Query: KETPKSLWLKDLDALEKELDEMDKNDA----QAEEVRRQQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMDTTSSSTTTEVASNVVVKPKGKAA
+ ++ +DLDALEK LD+ D D Q E ++++ + + K KIS K + + T + P + TT S+ + + K
Subjt: KETPKSLWLKDLDALEKELDEMDKNDA----QAEEVRRQQRITSNNEVKQKISRNAPKTPRNSKKTTISDPVAESMDTTSSSTTTEVASNVVVKPKGKAA
Query: PRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAVAVDDDGEDDDEVL
+ + S T P K ++ V++D D + DD+V+
Subjt: PRKAPAKKLSFKTPPSSMITWKSYDCFIMGQQQGKAVAVDDDGEDDDEVL
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