CuGenDBv2

Gene ID	Sed0023599
Organism	Sechium edule (Chayote v1)
Description	macrophage migration inhibitory factor homolog
Genome location	LG12:32319033..32322382
RNA-Seq Expression	Sed0023599
Synteny	Sed0023599
Gene Ontology terms	GO:0005615 - extracellular space (cellular component) GO:0005634 - nucleus (cellular component) GO:0005737 - cytoplasm (cellular component) GO:0050178 - phenylpyruvate tautomerase activity (molecular function)
InterPro domains	IPR001398 - Macrophage migration inhibitory factor IPR014347 - Tautomerase/MIF superfamily

Homology

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GenBank top hits

e value

%identity

Alignment

XP_022134572.1 macrophage migration inhibitory factor homolog [Momordica charantia]

3.7e-49

87.83

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MPTLNLFTNVPVD+VVAAD LKDA+KAVSKI+GKPE+YVMILLNG TPI FAGTEEPAAY ELISIGGLGPSVNGKLSSTIAEI+QTKLHID SRFY+KF
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQASYFGYNGSTF
        YD + SYFGYNGSTF
Subjt:  YDVQASYFGYNGSTF

XP_022925771.1 macrophage migration inhibitory factor homolog [Cucurbita moschata]

7.4e-50

92.17

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MPTLNLFTN+PVD+VVAAD LKDASKAVSKILGK ESYVMILLNGSTPIVFAGTEEP AY ELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFY+KF
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQASYFGYNGSTF
         DVQAS+FGYNGSTF
Subjt:  YDVQASYFGYNGSTF

XP_022973339.1 macrophage migration inhibitory factor homolog [Cucurbita maxima]

4.4e-50

93.04

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MPTLNLFTN PVD+VVAAD LKDASKAVSKILGK ESYVMILLNGSTPIVFAGTEEPAAY ELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFY+KF
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQASYFGYNGSTF
         DVQAS+FGYNGSTF
Subjt:  YDVQASYFGYNGSTF

XP_023529457.1 macrophage migration inhibitory factor homolog [Cucurbita pepo subsp. pepo]

1.3e-49

92.17

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MPTLNLFTN+PVD+VVAAD LKDASKAVSKILGK ESYVMILLNGSTPIVFAGTEEPAAY ELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFY+KF
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQASYFGYNGSTF
         D QAS+FGYNGSTF
Subjt:  YDVQASYFGYNGSTF

XP_038879720.1 macrophage migration inhibitory factor homolog isoform X1 [Benincasa hispida]

2.3e-51

93.04

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MPTLNLFTNVPVD+VVAAD LKDASKA+SKILGKPESYVMILLNGSTPIVFAGTEEPAAY ELISIGGLGP VNGKLSSTIAEI+QTKL IDSSRFY+KF
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQASYFGYNGSTF
        YDVQASYFGYNGSTF
Subjt:  YDVQASYFGYNGSTF

TrEMBL top hits

e value

%identity

Alignment

A0A068V7C4 Uncharacterized protein

2.6e-48

86.96

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MPTLNLFTNVPVDSVVA+D LKDA+KAV+KI+GKPESYVMIL+NG  PI FAGTEEPAAY ELISIGGLGPSVNGKLSSTIAEI+QTKL IDSSRFY+KF
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQASYFGYNGSTF
        YDVQ SYFG+NGSTF
Subjt:  YDVQASYFGYNGSTF

A0A6J1BZZ0 macrophage migration inhibitory factor homolog

1.8e-49

87.83

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MPTLNLFTNVPVD+VVAAD LKDA+KAVSKI+GKPE+YVMILLNG TPI FAGTEEPAAY ELISIGGLGPSVNGKLSSTIAEI+QTKLHID SRFY+KF
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQASYFGYNGSTF
        YD + SYFGYNGSTF
Subjt:  YDVQASYFGYNGSTF

A0A6J1ED40 macrophage migration inhibitory factor homolog

3.6e-50

92.17

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MPTLNLFTN+PVD+VVAAD LKDASKAVSKILGK ESYVMILLNGSTPIVFAGTEEP AY ELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFY+KF
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQASYFGYNGSTF
         DVQAS+FGYNGSTF
Subjt:  YDVQASYFGYNGSTF

A0A6J1IEA5 macrophage migration inhibitory factor homolog

2.1e-50

93.04

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MPTLNLFTN PVD+VVAAD LKDASKAVSKILGK ESYVMILLNGSTPIVFAGTEEPAAY ELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFY+KF
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQASYFGYNGSTF
         DVQAS+FGYNGSTF
Subjt:  YDVQASYFGYNGSTF

A0A6P6SI69 macrophage migration inhibitory factor homolog

2.6e-48

86.96

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MPTLNLFTNVPVDSVVA+D LKDA+KAV+KI+GKPESYVMIL+NG  PI FAGTEEPAAY ELISIGGLGPSVNGKLSSTIAEI+QTKL IDSSRFY+KF
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQASYFGYNGSTF
        YDVQ SYFG+NGSTF
Subjt:  YDVQASYFGYNGSTF

SwissProt top hits

e value

%identity

Alignment

O44786 Macrophage migration inhibitory factor homolog

4.6e-18

43.48

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MP   + TN P DS+ +A  LK A   V K LGKPESYV I +NG  P+VF G+E+P     L SIG +GP VN   +  + +++  +L I  +R Y++ 
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQASYFGYNGSTF
         D++AS   +NGSTF
Subjt:  YDVQASYFGYNGSTF

P34884 Macrophage migration inhibitory factor

3.8e-12

33.91

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MP   + TNVP  S V    L + ++ +++  GKP  Y+ + +     + F+GT +P A   L SIG +G + N   S  +  ++  +LHI   R Y+ +
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQASYFGYNGSTF
        YD+ A+  G+NGSTF
Subjt:  YDVQASYFGYNGSTF

P81529 Macrophage migration inhibitory factor homolog

2.0e-13

37.39

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MP   L TN+     V +D L   S  V  IL KP SYV + +N    + F G+ +PAA+  L+SIGG+ PS N   S+ + + +  KL I  +R Y+ F
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQASYFGYNGSTF
         ++     G+NG+TF
Subjt:  YDVQASYFGYNGSTF

P81748 Macrophage migration inhibitory factor homolog

5.4e-19

41.74

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MP     TNVP ++ ++ D LK  SK ++ +LGKPESYV + +NG   I F GT+ PA + +L+S+GG+G   N   S+ + + +   L I  +R Y+ F
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQASYFGYNGSTF
         D++ S  GYNGSTF
Subjt:  YDVQASYFGYNGSTF

P91850 Macrophage migration inhibitory factor homolog

1.9e-19

44.35

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MP   + TN+P +S+ +A  LK AS  V+K LGKPESYV I +NG   +VF G+E+P A   L SIG +GP VN   +  + +++  +L I  +R Y++F
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQASYFGYNGSTF
         D++AS   +NGSTF
Subjt:  YDVQASYFGYNGSTF

Arabidopsis top hits

e value

%identity

Alignment

AT3G51660.1 Tautomerase/MIF superfamily protein

3.0e-17

Show/hide

Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MP L + TNV  D V       + +KAV+ I+G+P++ VM++L GS  IVF G +E AAYAE++S+GG+   V  +L +T+  I+ T   I  +RF  K 
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQA
        +D+ +
Subjt:  YDVQA

AT5G01650.1 Tautomerase/MIF superfamily protein

5.2e-33

57.02

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MP LNL TNV +D V  +  L +AS  V+KI+GKPE+YVMI+L GS P+ F GTE+PAAY EL+SIGGL   VN KLS+ ++ I++TKL +  SRF++KF
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQASYFGYNGST
        YD + S+FG+NG+T
Subjt:  YDVQASYFGYNGST

AT5G01650.2 Tautomerase/MIF superfamily protein

1.0e-28

56.73

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MP LNL TNV +D V  +  L +AS  V+KI+GKPE+YVMI+L GS P+ F GTE+PAAY EL+SIGGL   VN KLS+ ++ I++TKL +  SRF++KF
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQ
        YD +
Subjt:  YDVQ

AT5G57170.1 Tautomerase/MIF superfamily protein

2.4e-46

77.39

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MPTLNLFTN+PVD+V  +D LKDA+KAV+KI+GKPESYVMILLN   PI FAGTEEPAAY ELISIGGLGP VNGKLS TI+EI+Q KL IDSSRFY+KF
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQASYFGYNGSTF
        YD    +FGYNGSTF
Subjt:  YDVQASYFGYNGSTF

AT5G57170.2 Tautomerase/MIF superfamily protein

8.0e-42

77.36

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Query:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF
        MPTLNLFTN+PVD+V  +D LKDA+KAV+KI+GKPESYVMILLN   PI FAGTEEPAAY ELISIGGLGP VNGKLS TI+EI+Q KL IDSSRFY+KF
Subjt:  MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKF

Query:  YDVQAS
        YD   S
Subjt:  YDVQAS

Sequences

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CDS sequence

Show/hide CDS sequence

ATGCCGACTTTGAATCTGTTCACCAATGTCCCAGTTGATTCCGTCGTGGCCGCCGACACTCTCAAGGACGCATCCAAAGCTGTCTCTAAAATTCTTGGGAAGCCCGAATC
TTATGTGATGATCTTGCTGAATGGTAGCACGCCGATCGTATTTGCTGGCACGGAAGAACCAGCTGCGTATGCGGAATTGATCTCTATCGGAGGCCTCGGACCAAGCGTGA
ATGGAAAACTTAGCTCAACAATTGCTGAGATTATTCAGACTAAGCTTCATATTGATAGCTCCCGTTTCTATGTCAAATTTTATGACGTTCAGGCATCGTATTTCGGATAC
AACGGCTCAACATTTTGA

mRNA sequence

Show/hide mRNA sequence

GTGGCATTAAGTTTTTCTTCTCATTTCTGTGTTCACTTCACTGTACGAAATCTTATCTGCAAGACTGTAGAGGGAATGTCCTTTCTCCTTAAGGATTAAGCCAAGCTTGA
AAGTTGAAACCATAGCTTCGCCATTAGAAGAACCTTCAAGCTAAATTGGGCCATCCCCAGTAGCAGCACCAGAGTAACAATGCCGACTTTGAATCTGTTCACCAATGTCC
CAGTTGATTCCGTCGTGGCCGCCGACACTCTCAAGGACGCATCCAAAGCTGTCTCTAAAATTCTTGGGAAGCCCGAATCTTATGTGATGATCTTGCTGAATGGTAGCACG
CCGATCGTATTTGCTGGCACGGAAGAACCAGCTGCGTATGCGGAATTGATCTCTATCGGAGGCCTCGGACCAAGCGTGAATGGAAAACTTAGCTCAACAATTGCTGAGAT
TATTCAGACTAAGCTTCATATTGATAGCTCCCGTTTCTATGTCAAATTTTATGACGTTCAGGCATCGTATTTCGGATACAACGGCTCAACATTTTGATCAGTATTTTGTA
GGATCAACAGCAAAATGCTGTCGAATTACGAAAATTGTGGAGTAATGTGATTATGAAGAGTTGGTTGGAACCAACATTCTTTGCCTATAAAATATTTGAATGGATGTGGG
TGTAAAGAATTATTTTGCATCTCGAGTGTCTGAATGTTTCGTGTTTATAACTATTACGTGCTAAGCTTGTGAATCTAAAAAAAAAATGAAGTCTAATGCTTTTGGAGAGA
TGAAATTCATGGTAGTGAAATCAATCGAGGAACTCTTTAACCGTCATGGGGTGGCTCAATTGGGCACAGAAAGCCTTCGGAGTGCAAAAGATGATGTGTTCAATCTCCAT
GATGGCCACCTACTCCTTGACATCCAAATGTTGTAGGGTCAGGCGGTATGTTTCATGACATTAGTCGAGGTGCGCGCAAGCTGGCTCAGACAGTCACGGATATCAAAAAA
TATATATATCAACAAACTTTAGGGTGTGTTTGGGCCCGTTTATATAAACGACTGAGTTTGTTATAATAACTCAATCGATGTTTGTCTCACCGTTTATTATAAACGGTGGT
TACCTAAATGTATATGTCCATTTATTTCAACTTTATATATATTGCTTTTTATTATAACCAACCATTCAAATACTGTTTATCATAA

Protein sequence

Show/hide protein sequence

MPTLNLFTNVPVDSVVAADTLKDASKAVSKILGKPESYVMILLNGSTPIVFAGTEEPAAYAELISIGGLGPSVNGKLSSTIAEIIQTKLHIDSSRFYVKFYDVQASYFGY
NGSTF

Sed0023599 (gene) of Chayote v1 genome