CuGenDBv2

Gene ID	Sgr026893
Organism	Siraitia grosvenorii cv. Qingpiguo (Monk fruit (Qingpiguo) v1)
Description	dCTP pyrophosphatase 1
Genome location	tig00153047:1876777..1877282
RNA-Seq Expression	Sgr026893
Synteny	Sgr026893
Gene Ontology terms	GO:0006253 - dCTP catabolic process (biological process) GO:0042262 - DNA protection (biological process) GO:0005829 - cytosol (cellular component) GO:0000287 - magnesium ion binding (molecular function) GO:0047840 - dCTP diphosphatase activity (molecular function)
InterPro domains	IPR025984 - dCTP pyrophosphatase 1

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6589527.1 dCTP pyrophosphatase 1, partial [Cucurbita argyrosperma subsp. sororia]

5.9e-41

78.51

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Query:  SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAA
        SYEPEK  KDVSLQELRD LAEFAR                 VGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL  AA
Subjt:  SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAA

Query:  LSKLVKNGKKYPVAAFARELP
        LSKLVKN  KYPVAAFAR LP
Subjt:  LSKLVKNGKKYPVAAFARELP

XP_004138182.1 dCTP pyrophosphatase 1 [Cucumis sativus]

9.1e-42

79.34

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Query:  SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAA
        SYEPEKT KDVSLQELRDRLAEFAR                 VGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL  AA
Subjt:  SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAA

Query:  LSKLVKNGKKYPVAAFARELP
        LSKLVKN  KYPVAAF R LP
Subjt:  LSKLVKNGKKYPVAAFARELP

XP_022921755.1 dCTP pyrophosphatase 1-like [Cucurbita moschata]

1.5e-41

79.34

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Query:  SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAA
        SYEPEKT KDVSLQELRD LAEFAR                 VGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL  AA
Subjt:  SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAA

Query:  LSKLVKNGKKYPVAAFARELP
        LSKLVKN  KYPVAAFAR LP
Subjt:  LSKLVKNGKKYPVAAFARELP

XP_022987438.1 dCTP pyrophosphatase 1-like [Cucurbita maxima]

5.9e-41

78.51

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Query:  SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAA
        SYEPEKT KDVSLQELRD L EFAR                 VGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL  AA
Subjt:  SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAA

Query:  LSKLVKNGKKYPVAAFARELP
        LSKLVKN  KYPVAAFAR LP
Subjt:  LSKLVKNGKKYPVAAFARELP

XP_038880679.1 dCTP pyrophosphatase 1-like [Benincasa hispida]

2.4e-42

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Query:  MES-SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL
        MES SYEPEKT KDVSLQELRDRLAEFAR                 VGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MES-SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL

Query:  ADAALSKLVKNGKKYPVAAFARELP
          AALSKLVKN  KYPVAAFAR LP
Subjt:  ADAALSKLVKNGKKYPVAAFARELP

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LP76 dCTP pyrophosphatase 1

4.4e-42

79.34

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Query:  SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAA
        SYEPEKT KDVSLQELRDRLAEFAR                 VGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL  AA
Subjt:  SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAA

Query:  LSKLVKNGKKYPVAAFARELP
        LSKLVKN  KYPVAAF R LP
Subjt:  LSKLVKNGKKYPVAAFARELP

A0A5A7UWT3 dCTP pyrophosphatase 1

4.9e-41

77.69

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Query:  SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAA
        SYEPEKT KDVSLQELRDRLAEFAR                 VGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL  AA
Subjt:  SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAA

Query:  LSKLVKNGKKYPVAAFARELP
        +SKLVKN  KYPVAA  R LP
Subjt:  LSKLVKNGKKYPVAAFARELP

A0A6J1E6P9 dCTP pyrophosphatase 1

7.5e-42

79.34

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Query:  SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAA
        SYEPEKT KDVSLQELRD LAEFAR                 VGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL  AA
Subjt:  SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAA

Query:  LSKLVKNGKKYPVAAFARELP
        LSKLVKN  KYPVAAFAR LP
Subjt:  LSKLVKNGKKYPVAAFARELP

A0A6J1F5P6 dCTP pyrophosphatase 1

4.9e-41

76.8

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Query:  MES-SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL
        MES SYEPEKT KDVSL ELRDRLAEFA+                 VGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEE+SDVLLYLVRLADVCGLDL
Subjt:  MES-SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL

Query:  ADAALSKLVKNGKKYPVAAFARELP
          AALSK+VKN  KYPVAAFAR LP
Subjt:  ADAALSKLVKNGKKYPVAAFARELP

A0A6J1JJF8 dCTP pyrophosphatase 1

2.8e-41

78.51

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Query:  SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAA
        SYEPEKT KDVSLQELRD L EFAR                 VGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL  AA
Subjt:  SYEPEKTVKDVSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAA

Query:  LSKLVKNGKKYPVAAFARELP
        LSKLVKN  KYPVAAFAR LP
Subjt:  LSKLVKNGKKYPVAAFARELP

SwissProt top hits

e value

%identity

Alignment

Q32KY6 dCTP pyrophosphatase 1

2.2e-14

53.42

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Query:  ARVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAALSKLVKNGKKYPV
        A VGEVGEL+E+FQWK + E G   WS  E+  L+EE+SD+L+YLV LA  C +DL  A L K+  N ++YPV
Subjt:  ARVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAALSKLVKNGKKYPV

Q91VC0 dCTP pyrophosphatase 1

7.5e-15

42.59

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Query:  SYEPEKTVKDVSL------------QELRDRLAEFARVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAALSKLV
        S+ PE T++D+              Q  + R    A VGEVGEL+E+FQWK + E G   W   E+  L+EE+SDVL+YLV LA  C +DL  A +SK+ 
Subjt:  SYEPEKTVKDVSL------------QELRDRLAEFARVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAALSKLV

Query:  KNGKKYPV
         N ++YPV
Subjt:  KNGKKYPV

Q9H773 dCTP pyrophosphatase 1

2.9e-14

43.93

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Query:  SYEPEKTVKDVSL------------QELRDRLAEFARVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAALSKLV
        S+ PE T++D+              Q  + R    A VGEVGEL+E+FQWK + E G   WS  E+  L+EE+SDVL+YLV LA  C +DL  A LSK+ 
Subjt:  SYEPEKTVKDVSL------------QELRDRLAEFARVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAALSKLV

Query:  KNGKKYP
         N ++YP
Subjt:  KNGKKYP

Q9QY93 dCTP pyrophosphatase 1

1.7e-14

42.06

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Query:  YEPEKTVKDVSL------------QELRDRLAEFARVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAALSKLVK
        + PE T++D+              Q  + R    A VGEVGEL+E+FQWK + E G   W   E+  L+EE+SDVL+YLV LA  C +DL  A +SK+  
Subjt:  YEPEKTVKDVSL------------QELRDRLAEFARVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAALSKLVK

Query:  NGKKYPV
        N ++YPV
Subjt:  NGKKYPV

Arabidopsis top hits

e value

%identity

Alignment

AT3G25400.1 CONTAINS InterPro DOMAIN/s: NTP Pyrophosphohydrolase MazG-related, RS21-C6 (InterPro:IPR011394), EAR (InterPro:IPR009039), NTP pyrophosphohydrolase MazG, putative catalytic core (InterPro:IPR004518); Has 1123 Blast hits to 1121 proteins in 452 species: Archae - 22; Bacteria - 753; Metazoa - 81; Fungi - 3; Plants - 83; Viruses - 0; Other Eukaryotes - 181 (source: NCBI BLink).

7.0e-24

56.31

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Query:  VSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAALSKLVKNGKK
        VSLQ L  ++ +FA+                 VGEVGELSEIFQWKGEV RG P+W   EK HL EE+SDVLLYLVRL+D CG+DL  AAL K+  N  K
Subjt:  VSLQELRDRLAEFAR-----------------VGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAALSKLVKNGKK

Query:  YPV
        YPV
Subjt:  YPV

Sequences

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CDS sequence

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ATGGAGAGTTCTTACGAGCCAGAGAAAACAGTAAAAGACGTCTCCCTTCAAGAACTCAGAGACAGGCTTGCAGAGTTTGCTCGAGTGGGTGAAGTGGGGGAGCTGTCGGA
GATATTCCAGTGGAAGGGGGAGGTGGAGAGGGGGCTCCCGAACTGGAGCGCGGCGGAGAAAGAGCATTTGGAGGAGGAAGTATCGGATGTGTTGCTTTATTTGGTGCGTC
TCGCCGACGTCTGCGGCCTTGATCTCGCCGACGCCGCCCTCTCCAAGCTCGTCAAAAATGGCAAGAAGTACCCAGTCGCCGCTTTCGCGCGCGAGCTCCCATAA

mRNA sequence

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Protein sequence

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MESSYEPEKTVKDVSLQELRDRLAEFARVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLADAALSKLVKNGKKYPVAAFARELP

Sgr026893 (gene) of Monk fruit (Qingpiguo) v1 genome