CuGenDBv2

Gene ID	Sgr028549
Organism	Siraitia grosvenorii cv. Qingpiguo (Monk fruit (Qingpiguo) v1)
Description	mediator of RNA polymerase II transcription subunit 18
Genome location	tig00153204:2220782..2223004
RNA-Seq Expression	Sgr028549
Synteny	Sgr028549
Gene Ontology terms	GO:0006357 - regulation of transcription by RNA polymerase II (biological process) GO:0006369 - termination of RNA polymerase II transcription (biological process) GO:0016592 - mediator complex (cellular component) GO:0070847 - core mediator complex (cellular component) GO:0003712 - transcription coregulator activity (molecular function)
InterPro domains	IPR019095 - Mediator complex, subunit Med18

Homology

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GenBank top hits

e value

%identity

Alignment

XP_008444669.1 PREDICTED: mediator of RNA polymerase II transcription subunit 18 [Cucumis melo]

2.6e-83

84.88

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Query:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQ                       GAVASEVRILCDLEQAEP WTVKHIGGA+RGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRF+RGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVA AVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GSNST
        G+ +T
Subjt:  GSNST

XP_011649597.2 mediator of RNA polymerase II transcription subunit 18 isoform X1 [Cucumis sativus]

5.3e-84

85.37

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Query:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQ                       GAVASEVRILCDLEQAEP WTVKHIGGA+RGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVA AVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GSNST
        G+ +T
Subjt:  GSNST

XP_022144379.1 mediator of RNA polymerase II transcription subunit 18 [Momordica charantia]

2.8e-85

86.83

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Query:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQ                       GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVA AVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GSNST
        G+ +T
Subjt:  GSNST

XP_023002016.1 mediator of RNA polymerase II transcription subunit 18 [Cucurbita maxima]

1.5e-83

84.39

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Query:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQ                       GAVASEVRI+CDLEQ EP+WTVKHIGGAMRG+GAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGF+FRFHRG HITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GSNST
        G+ +T
Subjt:  GSNST

XP_038885244.1 mediator of RNA polymerase II transcription subunit 18 [Benincasa hispida]

6.9e-84

84.88

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Query:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQ                       GAVASE+RILCDLEQAEP WTVKHIGGA+RGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVA AVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GSNST
        G+ +T
Subjt:  GSNST

TrEMBL top hits

e value

%identity

Alignment

A0A1S3BBM1 mediator of RNA polymerase II transcription subunit 18

1.3e-83

84.88

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Query:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQ                       GAVASEVRILCDLEQAEP WTVKHIGGA+RGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRF+RGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVA AVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GSNST
        G+ +T
Subjt:  GSNST

A0A5A7VHE6 Mediator of RNA polymerase II transcription subunit 18

1.7e-83

83.98

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Query:  LQHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLD
        ++HVEALEILLQ                       GAVASEVRILCDLEQAEP WTVKHIGGA+RGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLD
Subjt:  LQHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLD

Query:  HELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS
        HELLRVGFAFRF+RGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVA AVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS
Subjt:  HELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS

Query:  DGSNST
        DG+ +T
Subjt:  DGSNST

A0A6J1CS50 mediator of RNA polymerase II transcription subunit 18

1.4e-85

86.83

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Query:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQ                       GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVA AVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GSNST
        G+ +T
Subjt:  GSNST

A0A6J1GHW3 mediator of RNA polymerase II transcription subunit 18

2.2e-83

83.9

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Query:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQ                       GAVASEVRI+CDLEQ EP+WTVKHIGGAMRG+GAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGF+FRFHRG HITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVA AVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GSNST
        G+ +T
Subjt:  GSNST

A0A6J1KK74 mediator of RNA polymerase II transcription subunit 18

7.5e-84

84.39

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Query:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQ                       GAVASEVRI+CDLEQ EP+WTVKHIGGAMRG+GAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
Subjt:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGF+FRFHRG HITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GSNST
        G+ +T
Subjt:  GSNST

SwissProt top hits

e value

%identity

Alignment

Q9SJZ6 Mediator of RNA polymerase II transcription subunit 18

1.4e-74

71.71

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Query:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQ                       G V+SEVR+LCDL+Q EP WTVKH+GGAMRGAGA+Q+SVLVR M+ESKVSKN LR+FYALGYKLDH
Subjt:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELL+VGFAF F R AHI+V+VSSVNKM K+H+ DEAVPVTPG+Q+V+VTAPATSENYSEVA+AVS+FCE+LAPL+HLSKP ISTGVVPTAAAAAASL+SD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GSNST
        G  +T
Subjt:  GSNST

Arabidopsis top hits

e value

%identity

Alignment

AT2G22370.1 unknown protein

9.7e-76

71.71

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Query:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH
        QHVEALEILLQ                       G V+SEVR+LCDL+Q EP WTVKH+GGAMRGAGA+Q+SVLVR M+ESKVSKN LR+FYALGYKLDH
Subjt:  QHVEALEILLQ-----------------------GAVASEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELL+VGFAF F R AHI+V+VSSVNKM K+H+ DEAVPVTPG+Q+V+VTAPATSENYSEVA+AVS+FCE+LAPL+HLSKP ISTGVVPTAAAAAASL+SD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GSNST
        G  +T
Subjt:  GSNST

Sequences

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CDS sequence

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ATGGGCTTAATCCTTAATAAACGGTTCCGGGCGAGAAATTGCTCCGATTGCGAGATCGAGACCCCGAGAGAATTGAAGAAAGCCTCCATTAATCGTTCGTTTTCACTCGG
GTTGGCGTTTCTGGTTCGAAGTCTGAGGCAGTGGAGATGCAGCTGGGAATTTGAAGGTTCGGTTGAAGACGAATCGAAGTCGCCGCAGCATAGACTACGATGGAGTGTGT
GTATGATTCTGCAGCACGTTGAGGCCCTTGAGATACTTCTTCAAGGTGCCGTGGCTTCAGAGGTTCGGATCTTGTGTGACCTTGAGCAAGCTGAACCGGCGTGGACGGTT
AAACATATTGGAGGGGCAATGAGAGGTGCAGGTGCTGAACAACTCTCTGTTCTGGTTAGGACAATGGTAGAAAGCAAAGTTAGCAAGAATGTGCTTCGTCTATTCTATGC
ACTTGGCTACAAGTTAGACCATGAGCTGCTGAGAGTTGGTTTTGCTTTCCGCTTCCACCGGGGTGCTCACATAACTGTAACGGTTTCATCAGTTAATAAGATGTTAAAGC
TACATTCAACGGATGAGGCTGTACCTGTAACACCCGGTATACAGCTAGTTGAAGTGACAGCCCCAGCAACTTCTGAAAACTATTCTGAAGTAGCCAGTGCAGTGTCGACT
TTCTGTGAATATCTTGCACCGCTGCTGCATTTGTCAAAACCGGGAATATCCACAGGTGTTGTTCCTACTGCTGCTGCCGCTGCAGCATCTCTTCTATCTGATGGATCAAA
TTCTACAAGGCTTCAAGAAACACAGGGACTGACTGATCGATCAACTGATCTGCTTGGGGATGGTCGACTTGAAATCCGAATGCTGGATGTGGCTGTGAATTCATCTAAAC
TTTAG

mRNA sequence

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Protein sequence

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MGLILNKRFRARNCSDCEIETPRELKKASINRSFSLGLAFLVRSLRQWRCSWEFEGSVEDESKSPQHRLRWSVCMILQHVEALEILLQGAVASEVRILCDLEQAEPAWTV
KHIGGAMRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSENYSEVASAVST
FCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGSNSTRLQETQGLTDRSTDLLGDGRLEIRMLDVAVNSSKL

Sgr028549 (gene) of Monk fruit (Qingpiguo) v1 genome