| GenBank top hits | e value | %identity | Alignment |
|---|
| KAG6606989.1 Nicastrin, partial [Cucurbita argyrosperma subsp. sororia] | 0.0e+00 | 86.58 | Show/hide |
Query: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
ME+VPDLQNSMYLVVDGYPCIRLLNLSGE+ +PGREKVVVPMINFKDADEI+QPSAILVSMD+ISSFF RL+DDSNFA+NVGGVLI+PGTEIQ RTKG
Subjt: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
Query: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
FSPAQKFPQA+FAPYQKIDY+WN I AASKNVK+KK YTSNVAEFDLVMQTTK GT NS++CLK+E CLPLGGYS
Subjt: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
Query: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
VWSSLPPINI SSD+SKP+ILT ASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSD+VSG
Subjt: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
Query: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
LN+ LIDTVFEIGSVGK N GFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIK+SPASTTNPGIPPSSLMAFL KNS VSGVVLEDFDTSFTNQFY
Subjt: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
Query: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
QSHLDD+HNINSSAIEAAALLVARTLYILATNKKELSSSA AIK+NTSLVEELIGCLLNCDPGLSCELVKRYISP+N CPNHYVGVILDEPSSTPYPGY
Subjt: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
Query: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
++DVSRF WNFLADRTSI KENTSSVCSQNCDDKSEVCIGAETG+GTCV+STTRYVPAYSTRL F+SGSW VLP N+SDPMGAVDPVWTESNWNTIGLRM
Subjt: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
Query: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
YT+QATAYDRFVLLGGI TTIL+YFAIV VRGSI+KALK+D
Subjt: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
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| XP_022143375.1 nicastrin [Momordica charantia] | 0.0e+00 | 86.9 | Show/hide |
Query: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
ME+VPDLQNSMYLVVDGYPCIRLLNLSGE+ +PGREKVVVPMINFKDADE+ QPSAI+VSMDEISSFF+RLKDDSNFANNVGGVLIEPGTE+QNRT+G
Subjt: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
Query: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
FSPA+KFPQAEFAPYQK+DYDWN I A+SKNVKNKKAYTSNVAEFDLVMQTTK GTHNS++CLK+E CLPLGGYS
Subjt: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
Query: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
VWSSLPPINI SSDQSKP+ILT ASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVF VFTGESWGYLGSRRFLLELDLQSD VSG
Subjt: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
Query: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
LN++LIDTVFEIGSVGKS +HG GNFFAHMTEVSSSKNETWNALK AQESLPFE KISPASTTNPGIPPSSLMAFL KNS VSGVVLEDFDT FTNQFY
Subjt: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
Query: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
QSHLDD++NINSSAIEAAALLVARTLYILATNKKEL SSA T+IKVNTSLVEELIGCLLNCDPGLSCELVKRYISP++ CPNHYVGVILDEPSSTPYPGY
Subjt: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
Query: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
++DVSRFVWNFLADRTSI KENTSS CS NC+DKSEVCIGAE G+GTCVISTTRYVPAYSTRLK+ESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
Subjt: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
Query: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
YTIQ TAYDRFVLLGGI TTILAYFAIV VRGSI+KALKRD
Subjt: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
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| XP_022997757.1 nicastrin [Cucurbita maxima] | 0.0e+00 | 86.9 | Show/hide |
Query: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
ME+VPDLQNSMYLVVDGYPCIRLLNLSGE+ +PGREKVVVPMINFKDADEI QPSAILVSMD+ISSFF RL+DDSNFA+NVGGVLI+PGTEIQ RTKG
Subjt: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
Query: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
FSPAQKFPQA+FAPYQKIDY+WN I AASKNVK+KK YTSNVAEFDLVMQTTK GTHNS++CLK+E CLPLGGYS
Subjt: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
Query: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
VWSSLPPINI S D+SKP+ILT ASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSD+VSG
Subjt: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
Query: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
LN+ LIDTVFEIGSVGK N GFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIK+SPASTTNPGIPPSSLMAFL KNS VSGVVLEDFDTSFTNQFY
Subjt: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
Query: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
QSHLDD+HNINSSAIEAAALLVARTLYILATNKKELSSSA AIK+NTSLVEE+IGCLLNCDPGLSCELVKRYISP N CPNHYVGVILDEPSSTPYPGY
Subjt: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
Query: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
++DVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETG+GTCV+STTRYVPAYSTRL FESGSW VLP NSSDPMGAVDPVWTESNWNTIGLR
Subjt: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
Query: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
YT+QATAYDRFVLLGGI TTIL+YFAIV VRGSI+KALK+D
Subjt: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
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| XP_023525268.1 nicastrin [Cucurbita pepo subsp. pepo] | 0.0e+00 | 86.74 | Show/hide |
Query: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
ME+VPDLQNSMYLVVDGYPCIRLLNLSGE+ +PGREKVVVPMINFKDADEI+QPSAILVSMD+ISSFF RL+DDSNFA+NVGGVLI+PGTEIQ RTKG
Subjt: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
Query: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
FSPAQKFPQA+FAPYQKIDY+WN I AASKNVK+KK YTSNVAEFDLVMQTTK GTHNS++CLK+E CLPLGGYS
Subjt: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
Query: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
VWSSLPPINI SSD+SKP+ILT ASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQS++VSG
Subjt: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
Query: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
LN+ LIDTVFEIGSVGK N GFGNFFAHMTEVSSSKNETWNALKLA+ESLPFENIK+SPASTTNPGIPPSSLMAFL KNS VSGVVLEDFDTSFTNQFY
Subjt: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
Query: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
QSHLDD+HNINSSAIEAAALLVARTLYILATNKKELSSSA AIK+NTSLVEELIGCLLNCDPGLSCELVKRYISP+N CPNHYVGVILDEPSSTPYPGY
Subjt: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
Query: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
++DVSRF WNFLADRTSI KENTSSVCSQNCDDKSEVCIGAETG+GTCV+STTRYVPAYSTRL FESGSW VLP NSSDPMGAVDPVWTESNWNTIGLRM
Subjt: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
Query: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
YT+QATAYDRFVLLGGI TTIL+YFAIV VRGSI+KALK+D
Subjt: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
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| XP_038896057.1 nicastrin [Benincasa hispida] | 0.0e+00 | 86.9 | Show/hide |
Query: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
ME+VPDLQNSMYL VDGYPCIRLLNLSGE+ +PGREKVVVPMINFKDADEI+QPSA+LVSMDEISSFFTRL+DDS+FANNVGGVLI+PGTE+QN TKG
Subjt: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
Query: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
FSPAQKFPQA FAPY+KIDY+WN I AASKNVKNKK Y SNVAEFDLVMQTTK GTHNS++CLK+ CLPLGGYS
Subjt: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
Query: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
VWSSLPPIN SSSDQSKPVILT ASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDG DDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
Subjt: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
Query: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
LN+RLID+VFEIGSVGKS +HGFG FFAHMTEVSSSKNETWNALKLA+ESLP ENIK+SPASTTNPGIPPSSLMAFL KN +SGVVLEDFDTSFTNQFY
Subjt: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
Query: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
QSHLDD+HNINSSAIEAAALLVARTLYILATNKKELSSSA TAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPS+ CPNHYVGVILDEPSSTPYPGY
Subjt: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
Query: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
++DVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETG+GTCVISTTRY+PAYSTRLKFESG W VLP NSSDP+GAVDPVWTESNWNTIGLRM
Subjt: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
Query: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
YTIQATAYDRFVLLGGI TTILAYFAIV V+ SI+KALKRD
Subjt: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
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| TrEMBL top hits | e value | %identity | Alignment |
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| A0A1S3C4C7 Nicastrin | 0.0e+00 | 84.71 | Show/hide |
Query: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
ME+VPDLQNSMYL VDGYPCIRLLNLSGE+ +PGREKVV+PMINFKDADEI++PSA+LVSMD ISSFFTRL+DDS+FANNVGGVLIEPGT IQNRT+G
Subjt: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
Query: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
FSPAQKFPQA+FAPY+K DY+WN I AASKNVK+KK Y SNVAEFDLVMQTTK GTH+S++CLK+E CLPLGGYS
Subjt: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
Query: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
VWSSLPPIN SSSDQSKPVILT ASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
Subjt: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
Query: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
L++RLID VFEIGSVGKS NHG GNFFAHMTEVSSSKNETWNALKLA+ESLP ENIK+SPASTTNPGIPPSSLMAFL KN +SGVVL+DFDT FTNQFY
Subjt: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
Query: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
QSHLDD+HNINSSAIEAAALLVARTLYILA NK ELSSS TAIKVNTSLVEELIGCLLNCDPGLSCELVKRYI+PS+ CPNHYVGVILDEPSS PYP Y
Subjt: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
Query: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
++DVSRFVWNFLADRTSIPKENTSSVCSQNCDD+SEVCIGAETG+GTCVISTTRY+PAYSTRLKFESG W VLP NSSD +GAVDPVWTESNWNTIGLR+
Subjt: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
Query: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
YTIQA AYDRFVLLGGI TTILAYFAIV VR SI+KALKRD
Subjt: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
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| A0A1S3C4S1 Nicastrin | 7.0e-294 | 81.28 | Show/hide |
Query: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
ME+VPDLQNSMYL VDGYPCIRLLNLSGE+ +PGREKVV+PMINFKDADEI++PSA+LVSMD ISSFFTRL+DDS+FANNVGGVLIEPGT IQNRT+G
Subjt: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
Query: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
FSPAQKFPQA+FAPY+K DY+WN I AASKNVK+KK Y SNVAEFDLVMQTTK GTH+S++CLK+E CLPLGGYS
Subjt: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
Query: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
VWSSLPPIN SSSDQSKPVILT ASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
Subjt: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
Query: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
L++RLID VSSSKNETWNALKLA+ESLP ENIK+SPASTTNPGIPPSSLMAFL KN +SGVVL+DFDT FTNQFY
Subjt: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
Query: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
QSHLDD+HNINSSAIEAAALLVARTLYILA NK ELSSS TAIKVNTSLVEELIGCLLNCDPGLSCELVKRYI+PS+ CPNHYVGVILDEPSS PYP Y
Subjt: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
Query: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
++DVSRFVWNFLADRTSIPKENTSSVCSQNCDD+SEVCIGAETG+GTCVISTTRY+PAYSTRLKFESG W VLP NSSD +GAVDPVWTESNWNTIGLR+
Subjt: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
Query: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
YTIQA AYDRFVLLGGI TTILAYFAIV VR SI+KALKRD
Subjt: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
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| A0A6J1CNM4 Nicastrin | 0.0e+00 | 86.9 | Show/hide |
Query: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
ME+VPDLQNSMYLVVDGYPCIRLLNLSGE+ +PGREKVVVPMINFKDADE+ QPSAI+VSMDEISSFF+RLKDDSNFANNVGGVLIEPGTE+QNRT+G
Subjt: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
Query: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
FSPA+KFPQAEFAPYQK+DYDWN I A+SKNVKNKKAYTSNVAEFDLVMQTTK GTHNS++CLK+E CLPLGGYS
Subjt: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
Query: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
VWSSLPPINI SSDQSKP+ILT ASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVF VFTGESWGYLGSRRFLLELDLQSD VSG
Subjt: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
Query: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
LN++LIDTVFEIGSVGKS +HG GNFFAHMTEVSSSKNETWNALK AQESLPFE KISPASTTNPGIPPSSLMAFL KNS VSGVVLEDFDT FTNQFY
Subjt: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
Query: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
QSHLDD++NINSSAIEAAALLVARTLYILATNKKEL SSA T+IKVNTSLVEELIGCLLNCDPGLSCELVKRYISP++ CPNHYVGVILDEPSSTPYPGY
Subjt: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
Query: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
++DVSRFVWNFLADRTSI KENTSS CS NC+DKSEVCIGAE G+GTCVISTTRYVPAYSTRLK+ESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
Subjt: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
Query: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
YTIQ TAYDRFVLLGGI TTILAYFAIV VRGSI+KALKRD
Subjt: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
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| A0A6J1GAI9 Nicastrin | 0.0e+00 | 86.27 | Show/hide |
Query: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
ME+VPDLQNSMYLVVDG+PCIRLLNLSGE+ +PGREKVVVPMINFKDADEI+QPSAILVSMD+ISSFF RL+DDSNFA+NVGGVLI+PGTEIQ RTKG
Subjt: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
Query: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
FSPAQKFPQA+FAPYQKIDY+WN I AASKNVK+KK YTSNVAEFDLVMQTTK GT NS++CLK+E CLPLGGYS
Subjt: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
Query: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
VWSSLPPINI SSD+SKP+ILT ASMDSASFFRDKSIGADSPISGLIALLA+VDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSD+VSG
Subjt: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
Query: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
LN+ LIDTVFEIGSVGK N GFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIK+SPASTTNPGIPPSSLMAFL KNS VSGVVLEDFDTSFTNQFY
Subjt: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
Query: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
QSHLDD+HNINSSAIEAAALLVARTLYILATNKKELSSSA AIK+NTSLVEELIGCLLNCDPGLSCELVKRYISP+N CPNHYVGVILDEPSSTPYPGY
Subjt: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
Query: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
++DVSRF WNFLADRTSI KENTSSVCSQNCDDKSEVCIGAETG+GTCV+STTRYVPAYSTRL F+SGSW VLP N+SDPMGAVDPVWTESNWNTIGLRM
Subjt: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
Query: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
YT+QATAYDRFVLLGGI TTIL+YFAIV VRGSI+KALK+D
Subjt: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
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| A0A6J1K5Z2 Nicastrin | 0.0e+00 | 86.9 | Show/hide |
Query: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
ME+VPDLQNSMYLVVDGYPCIRLLNLSGE+ +PGREKVVVPMINFKDADEI QPSAILVSMD+ISSFF RL+DDSNFA+NVGGVLI+PGTEIQ RTKG
Subjt: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
Query: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
FSPAQKFPQA+FAPYQKIDY+WN I AASKNVK+KK YTSNVAEFDLVMQTTK GTHNS++CLK+E CLPLGGYS
Subjt: FSPAQKFPQAEFAPYQKIDYDWNSI--------------------------AASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
Query: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
VWSSLPPINI S D+SKP+ILT ASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSD+VSG
Subjt: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
Query: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
LN+ LIDTVFEIGSVGK N GFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIK+SPASTTNPGIPPSSLMAFL KNS VSGVVLEDFDTSFTNQFY
Subjt: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
Query: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
QSHLDD+HNINSSAIEAAALLVARTLYILATNKKELSSSA AIK+NTSLVEE+IGCLLNCDPGLSCELVKRYISP N CPNHYVGVILDEPSSTPYPGY
Subjt: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
Query: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
++DVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETG+GTCV+STTRYVPAYSTRL FESGSW VLP NSSDPMGAVDPVWTESNWNTIGLR
Subjt: INDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRM
Query: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
YT+QATAYDRFVLLGGI TTIL+YFAIV VRGSI+KALK+D
Subjt: YTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
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| SwissProt top hits | e value | %identity | Alignment |
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| F0ZBA6 Nicastrin | 1.4e-36 | 24.15 | Show/hide |
Query: YPCIRLLNLSGEVDPGREKVVVPMINFKDADEIVQPSAILVSMDEISSF-----FTRLKD-----DSNFANNVGGVLIEPGTEIQ--------NRTKGFS
YPC +++ G+ F + + S IL +D+ S+ +++ KD D+N+ N+ + + ++I+ +T +S
Subjt: YPCIRLLNLSGEVDPGREKVVVPMINFKDADEIVQPSAILVSMDEISSF-----FTRLKD-----DSNFANNVGGVLIEPGTEIQ--------NRTKGFS
Query: PAQKFPQAEFAPYQKIDYDWNSIA---------------------ASKNVKNKK---AYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYSVWSS
P ++P + Y + +WN A A +NV Y + AE D MQ G NS TCL+ C P+GG S+WSS
Subjt: PAQKFPQAEFAPYQKIDYDWNSIA---------------------ASKNVKNKK---AYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYSVWSS
Query: LPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLE-LDLQSDAVSGLND
S D+ K +IL D+ +FFRD SIGAD + LL+ + +L+ VD +K++VF + E WGY+GS F+ + L+ Q +
Subjt: LPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLE-LDLQSDAVSGLND
Query: RLID------------------TVFEIGSVGKS-FNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVS
+ ID T+ E+ +G++ + G + ++ + + + L Q + +EN I+ TT +PPSS M+FL K + +
Subjt: RLID------------------TVFEIGSVGKS-FNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVS
Query: GVVLEDFDTSFTNQFYQSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHY
VV+ D D ++N +Y DD N+ S + +YIL+T + + I ++ + + L C + ++C + P N PN Y
Subjt: GVVLEDFDTSFTNQFYQSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHY
Query: VGVILDEPSSTPYPGYINDVSRFVWNFLADRTSIPKEN-TSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGS--WYVLPSNSSDPM
V ++T P + R ++ SI + N T + C+ + D S +C G CV S T A S F++ W ++ S+
Subjt: VGVILDEPSSTPYPGYINDVSRFVWNFLADRTSIPKEN-TSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPAYSTRLKFESGS--WYVLPSNSSDPM
Query: GAVDPVWTESNWNTIGLRMYTIQATAYDRFVLLGGIATTILAYFAIVGVR
P++TESNW+ L+++ I + + + L+ G+ +++ I+ V+
Subjt: GAVDPVWTESNWNTIGLRMYTIQATAYDRFVLLGGIATTILAYFAIVGVR
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| P57716 Nicastrin | 1.1e-22 | 27.65 | Show/hide |
Query: CLPLGGYSVWSSLPPINIS-SSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLEL
C PL Y+VWS L PIN S + V++ A +DS SFF + + GA+S ++ + LAA +AL + L + ++FV F GE++ Y+GS R + ++
Subjt: CLPLGGYSVWSSLPPINIS-SSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLEL
Query: DLQSDAVSGLNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSS-KNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLED
+ V N ID+ E+G V + M++ + S KN+ + L ++S + + +PPSSL FL + +SGVVL D
Subjt: DLQSDAVSGLNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSS-KNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLED
Query: FDTSFTNQFYQSHLDDIHNIN-------------------SSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVK
SF N++YQS D NIN + A+ A ++AR LY LA SSS + + T L L G L+ + ++K
Subjt: FDTSFTNQFYQSHLDDIHNIN-------------------SSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVK
Query: RYISP--SNACPNHYVGVILDEPSSTPYPGYINDVSRFVWNFLADRTSIPKE---NTSSVCSQNCD--DKSEVCIGAETGR----GTCVISTTRYVPAYS
+ + HY+ V P++T Y V + N T++ +E + S V +++ D + S V + R CV ST R A S
Subjt: RYISP--SNACPNHYVGVILDEPSSTPYPGYINDVSRFVWNFLADRTSIPKE---NTSSVCSQNCD--DKSEVCIGAETGR----GTCVISTTRYVPAYS
Query: TRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRMYTIQATAYDRFVLLGGIATTILA
FE W SS W ES W I R++ I + + L+ G +T + +
Subjt: TRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRMYTIQATAYDRFVLLGGIATTILA
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| Q54JT7 Nicastrin | 2.8e-37 | 23.87 | Show/hide |
Query: LQNSMYLVVDGYPCIRLLNLSGEV----DPGREKVVVPMINFKDADEIV-------QPSAILVSMDEISSFFTR-LKDDSNFANNVGGVLIEPGTEIQNR
+++ MY ++ YPC R++ L+G++ G + ++ +I D+DE Q I+V D S++F + L + + G L+ T+I +
Subjt: LQNSMYLVVDGYPCIRLLNLSGEV----DPGREKVVVPMINFKDADEIV-------QPSAILVSMDEISSFFTR-LKDDSNFANNVGGVLIEPGTEIQNR
Query: TKGFSPAQKFPQAEFAPYQKIDYDWNS------------------------IAASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGY
T +SP ++P +F Y + +WN I + Y + AE D MQ G N+ TCL+ C P+GG
Subjt: TKGFSPAQKFPQAEFAPYQKIDYDWNS------------------------IAASKNVKNKKAYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGY
Query: SVWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLE---------
S+WSS + DQSKP+IL +D+ +FFRD + G D L LL+ ++ L VD K+++F ++ E WGY+GS F+ +
Subjt: SVWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLE---------
Query: -------------LDLQSDAVSGLNDRLIDTVFEIGSVGKSFNHG--------FGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIP
LDL + + N I + E +G+ N G N H + N+ + +Q + +EN I TT +P
Subjt: -------------LDLQSDAVSGLNDRLIDTVFEIGSVGKSFNHG--------FGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIP
Query: PSSLMAFL------TKNSLVSGVVLEDFDTSFTNQFYQSHLDDIHNINSSAIEAAALLVARTLYILA---TNKKELSSSARTAIKVNTSLVEELIGCLLN
P S M+F+ + + + +V+ D D + N ++ D+ NIN++ TL+ + + +L + +KV+ + E+ CL
Subjt: PSSLMAFL------TKNSLVSGVVLEDFDTSFTNQFYQSHLDDIHNINSSAIEAAALLVARTLYILA---TNKKELSSSARTAIKVNTSLVEELIGCLLN
Query: CDPGLSCELVKRYIS--PSNACPNHYVGVILDEPSSTPYPGYINDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPA
++C V + +S P N PN Y GV P + P +RF++ T T+ +CD S +C+ C+ S T Y A
Subjt: CDPGLSCELVKRYIS--PSNACPNHYVGVILDEPSSTPYPGYINDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEVCIGAETGRGTCVISTTRYVPA
Query: YSTRLKFES--GSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRMYTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALK
S F++ SW ++ ++ PV+ ESNW+ +R++ + + A + + L+ G+ +L+ I ++ + K K
Subjt: YSTRLKFES--GSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRMYTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALK
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| Q8CGU6 Nicastrin | 2.1e-21 | 26.62 | Show/hide |
Query: CLPLGGYSVWSSLPPINISSS-DQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLEL
C PL Y+VWS L PIN S + V++ A +DS SFF + + GA+S ++ + LAA +AL + L + ++FV F GE++ Y+GS R + ++
Subjt: CLPLGGYSVWSSLPPINISSS-DQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLEL
Query: DLQSDAVSGLNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSS-KNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLED
+ V N ID+ E+G V + M++ + S KN+ + L ++S + + +PPSSL FL + +SGVVL D
Subjt: DLQSDAVSGLNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSS-KNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLED
Query: FDTSFTNQFYQSHLDDIHNIN-------------------SSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELI-GCLLNCDPGLSCELV
SF N++YQS D NIN + A+ A ++AR LY LA ++ +I+ + V L+ G L+ + ++
Subjt: FDTSFTNQFYQSHLDDIHNIN-------------------SSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELI-GCLLNCDPGLSCELV
Query: KRYISP--SNACPNHYVGVILDEPSSTPYPGYINDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEV------------CIGAETGRGT-----CVIS
+ + + HY+ V P++T Y V LA+ T +++ + C D S+V G T CV S
Subjt: KRYISP--SNACPNHYVGVILDEPSSTPYPGYINDVSRFVWNFLADRTSIPKENTSSVCSQNCDDKSEV------------CIGAETGRGT-----CVIS
Query: TTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRMYTIQATAYDRFVLLGGIATTILAYFAIV
T R A S FE W SS W ES W I R++ I + + L+ G +IL + IV
Subjt: TTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGLRMYTIQATAYDRFVLLGGIATTILAYFAIV
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| Q8GUM5 Nicastrin | 5.6e-224 | 60.96 | Show/hide |
Query: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
+E+VPDLQ MY+ VDG+PC+RLLNLSGE+ +PG KVV P+I KD ++VQP ILV+ DE+ FFTR+ D +FA+ +GGVL+E G+ Q + KG
Subjt: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
Query: FSPAQKFPQAEFAPYQKIDYDWNSIAAS---------------------KNVKNKK-----AYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
FSP ++FPQA+F+PY+ ++Y WNS A+S + +KK YTS+VAEF++VM+TTK GTHNS CL++ CLPLGGYS
Subjt: FSPAQKFPQAEFAPYQKIDYDWNSIAAS---------------------KNVKNKK-----AYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
Query: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
VWSSLPPI++SSS+ KPV+LT ASMD+ASFFRDKS GADSPISGL+ALL AVDALS VDG+ +L KQLVF+V TGE+WGYLGSRRFL ELDL SDAV+G
Subjt: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
Query: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
L++ I+TV EIGSVGK + G FFAH T VSS N T +ALK+AQ+SL +NIKI A T NPGIPPSSLMAF+ KN S VVLEDFDT+F N+FY
Subjt: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
Query: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
SHLDD+ NINSS++ AAA +VARTLYILA++ K+ S+SA +I VN S VEEL+ CLL C+PGLSC LVK YISP+N CP +Y GVIL EPSS PY GY
Subjt: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
Query: INDVSRFVWNFLADRTSIPKENTSSVCSQN-CDDKSEVCIGAETGR-GTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGL
+ DVSRF+WNFLAD+TS+ K NT+SVCS+ C EVCI AE+ + GTCV+STTRYVPAYSTRLK+ G+W +LP NSSD MG VDPVWTESNW+T+ +
Subjt: INDVSRFVWNFLADRTSIPKENTSSVCSQN-CDDKSEVCIGAETGR-GTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGL
Query: RMYTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
+YT+Q +AYD VL+ GI T LAY I+ + I KALK+D
Subjt: RMYTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
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| Arabidopsis top hits | e value | %identity | Alignment |
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| AT3G52640.1 Zn-dependent exopeptidases superfamily protein | 4.0e-225 | 60.96 | Show/hide |
Query: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
+E+VPDLQ MY+ VDG+PC+RLLNLSGE+ +PG KVV P+I KD ++VQP ILV+ DE+ FFTR+ D +FA+ +GGVL+E G+ Q + KG
Subjt: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
Query: FSPAQKFPQAEFAPYQKIDYDWNSIAAS---------------------KNVKNKK-----AYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
FSP ++FPQA+F+PY+ ++Y WNS A+S + +KK YTS+VAEF++VM+TTK GTHNS CL++ CLPLGGYS
Subjt: FSPAQKFPQAEFAPYQKIDYDWNSIAAS---------------------KNVKNKK-----AYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
Query: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
VWSSLPPI++SSS+ KPV+LT ASMD+ASFFRDKS GADSPISGL+ALL AVDALS VDG+ +L KQLVF+V TGE+WGYLGSRRFL ELDL SDAV+G
Subjt: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
Query: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
L++ I+TV EIGSVGK + G FFAH T VSS N T +ALK+AQ+SL +NIKI A T NPGIPPSSLMAF+ KN S VVLEDFDT+F N+FY
Subjt: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
Query: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
SHLDD+ NINSS++ AAA +VARTLYILA++ K+ S+SA +I VN S VEEL+ CLL C+PGLSC LVK YISP+N CP +Y GVIL EPSS PY GY
Subjt: QSHLDDIHNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVKRYISPSNACPNHYVGVILDEPSSTPYPGY
Query: INDVSRFVWNFLADRTSIPKENTSSVCSQN-CDDKSEVCIGAETGR-GTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGL
+ DVSRF+WNFLAD+TS+ K NT+SVCS+ C EVCI AE+ + GTCV+STTRYVPAYSTRLK+ G+W +LP NSSD MG VDPVWTESNW+T+ +
Subjt: INDVSRFVWNFLADRTSIPKENTSSVCSQN-CDDKSEVCIGAETGR-GTCVISTTRYVPAYSTRLKFESGSWYVLPSNSSDPMGAVDPVWTESNWNTIGL
Query: RMYTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
+YT+Q +AYD VL+ GI T LAY I+ + I KALK+D
Subjt: RMYTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
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| AT3G52640.2 Zn-dependent exopeptidases superfamily protein | 2.3e-220 | 58.33 | Show/hide |
Query: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
+E+VPDLQ MY+ VDG+PC+RLLNLSGE+ +PG KVV P+I KD ++VQP ILV+ DE+ FFTR+ D +FA+ +GGVL+E G+ Q + KG
Subjt: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
Query: FSPAQKFPQAEFAPYQKIDYDWNSIAAS---------------------KNVKNKK-----AYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
FSP ++FPQA+F+PY+ ++Y WNS A+S + +KK YTS+VAEF++VM+TTK GTHNS CL++ CLPLGGYS
Subjt: FSPAQKFPQAEFAPYQKIDYDWNSIAAS---------------------KNVKNKK-----AYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
Query: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
VWSSLPPI++SSS+ KPV+LT ASMD+ASFFRDKS GADSPISGL+ALL AVDALS VDG+ +L KQLVF+V TGE+WGYLGSRRFL ELDL SDAV+G
Subjt: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
Query: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
L++ I+TV EIGSVGK + G FFAH T VSS N T +ALK+AQ+SL +NIKI A T NPGIPPSSLMAF+ KN S VVLEDFDT+F N+FY
Subjt: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
Query: QSHLDDI-----------------------------HNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVK
SHLDD+ NINSS++ AAA +VARTLYILA++ K+ S+SA +I VN S VEEL+ CLL C+PGLSC LVK
Subjt: QSHLDDI-----------------------------HNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVK
Query: RYISPSNACPNHYVGVILDEPSSTPYPGYINDVSRFVWNFLADRTSIPKENTSSVCSQN-CDDKSEVCIGAETGR-GTCVISTTRYVPAYSTRLKFESGS
YISP+N CP +Y GVIL EPSS PY GY+ DVSRF+WNFLAD+TS+ K NT+SVCS+ C EVCI AE+ + GTCV+STTRYVPAYSTRLK+ G+
Subjt: RYISPSNACPNHYVGVILDEPSSTPYPGYINDVSRFVWNFLADRTSIPKENTSSVCSQN-CDDKSEVCIGAETGR-GTCVISTTRYVPAYSTRLKFESGS
Query: WYVLPSNSSDPMGAVDPVWTESNWNTIGLRMYTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
W +LP NSSD MG VDPVWTESNW+T+ + +YT+Q +AYD VL+ GI T LAY I+ + I KALK+D
Subjt: WYVLPSNSSDPMGAVDPVWTESNWNTIGLRMYTIQATAYDRFVLLGGIATTILAYFAIVGVRGSIVKALKRD
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| AT3G52640.3 Zn-dependent exopeptidases superfamily protein | 9.7e-187 | 58.12 | Show/hide |
Query: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
+E+VPDLQ MY+ VDG+PC+RLLNLSGE+ +PG KVV P+I KD ++VQP ILV+ DE+ FFTR+ D +FA+ +GGVL+E G+ Q + KG
Subjt: MEAVPDLQNSMYLVVDGYPCIRLLNLSGEV---DPGREKVVVPMINFKDADEIVQPSAILVSMDEISSFFTRLKDDSNFANNVGGVLIEPGTEIQNRTKG
Query: FSPAQKFPQAEFAPYQKIDYDWNSIAAS---------------------KNVKNKK-----AYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
FSP ++FPQA+F+PY+ ++Y WNS A+S + +KK YTS+VAEF++VM+TTK GTHNS CL++ CLPLGGYS
Subjt: FSPAQKFPQAEFAPYQKIDYDWNSIAAS---------------------KNVKNKK-----AYTSNVAEFDLVMQTTKVGTHNSITCLKDEACLPLGGYS
Query: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
VWSSLPPI++SSS+ KPV+LT ASMD+ASFFRDKS GADSPISGL+ALL AVDALS VDG+ +L KQLVF+V TGE+WGYLGSRRFL ELDL SDAV+G
Subjt: VWSSLPPINISSSDQSKPVILTAASMDSASFFRDKSIGADSPISGLIALLAAVDALSHVDGLDDLHKQLVFVVFTGESWGYLGSRRFLLELDLQSDAVSG
Query: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
L++ I+TV EIGSVGK + G FFAH T VSS N T +ALK+AQ+SL +NIKI A T NPGIPPSSLMAF+ KN S VVLEDFDT+F N+FY
Subjt: LNDRLIDTVFEIGSVGKSFNHGFGNFFAHMTEVSSSKNETWNALKLAQESLPFENIKISPASTTNPGIPPSSLMAFLTKNSLVSGVVLEDFDTSFTNQFY
Query: QSHLDDI-----------------------------HNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVK
SHLDD+ NINSS++ AAA +VARTLYILA++ K+ S+SA +I VN S VEEL+ CLL C+PGLSC LVK
Subjt: QSHLDDI-----------------------------HNINSSAIEAAALLVARTLYILATNKKELSSSARTAIKVNTSLVEELIGCLLNCDPGLSCELVK
Query: RYISPSNACPNHYVGVILDEPSSTPYPGYINDVSRFVWNFLADRTSIPKENTSSVCSQN-CDDKSEVCIGAETGR-GTCVISTTR
YISP+N CP +Y GVIL EPSS PY GY+ DVSRF+WNFLAD+TS+ K NT+SVCS+ C EVCI AE+ + GTCV+STTR
Subjt: RYISPSNACPNHYVGVILDEPSSTPYPGYINDVSRFVWNFLADRTSIPKENTSSVCSQN-CDDKSEVCIGAETGR-GTCVISTTR
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