CuGenDBv2

Gene ID	Sgr030373
Organism	Siraitia grosvenorii cv. Qingpiguo (Monk fruit (Qingpiguo) v1)
Description	DNA topoisomerase 2
Genome location	tig00153640:2971187..2977969
RNA-Seq Expression	Sgr030373
Synteny	Sgr030373
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0043231 - intracellular membrane-bounded organelle (cellular component) GO:0003677 - DNA binding (molecular function) GO:0046872 - metal ion binding (molecular function) GO:0005524 - ATP binding (molecular function) GO:0003918 - DNA topoisomerase type II (ATP-hydrolyzing) activity (molecular function)
InterPro domains	IPR013506 - DNA topoisomerase, type IIA, subunit B, domain 2 IPR036890 - Histidine kinase/HSP90-like ATPase superfamily IPR034157 - DNA topoisomerase 2, TOPRIM domain IPR031660 - C-terminal associated domain of TOPRIM IPR020568 - Ribosomal protein S5 domain 2-type fold IPR018522 - DNA topoisomerase, type IIA, conserved site IPR014721 - Ribosomal protein S5 domain 2-type fold, subgroup IPR013760 - DNA topoisomerase, type IIA-like domain superfamily IPR013759 - DNA topoisomerase, type IIA, subunit B, C-terminal IPR013758 - DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta IPR013757 - Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily IPR006171 - TOPRIM domain IPR003594 - Histidine kinase/HSP90-like ATPase IPR002205 - DNA topoisomerase, type IIA, subunit A/C-terminal IPR001241 - DNA topoisomerase, type IIA IPR001154 - DNA topoisomerase II, eukaryotic-type

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6581568.1 DNA topoisomerase 2, partial [Cucurbita argyrosperma subsp. sororia]

0.0e+00

88.51

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Query:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
        MAVEKKRPLQNSNAANVDS P      AGP KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
Subjt:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ

Query:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN
        RDPSMDS+KVVID EQN ISVFNNGDGVPVE+HQEE+VYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R KKYKQVFSDN
Subjt:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN

Query:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE
        MG KSEP ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ F TE PKRYHI+PNE
Subjt:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE

Query:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP
        RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP
Subjt:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP

Query:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
        +FLKNVATKSGIM+SVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGK+SEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
Subjt:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA

Query:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES
        SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+
Subjt:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES

Query:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI
        WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKKIEERKNWLR FE GTHLDQ+EKLIKYSDFVNKELILFS+
Subjt:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI

Query:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
        ADLQRSIPS+VDGLKPGQRKIL    +    K+ K   F               +  ST++ +  DFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
Subjt:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT

Query:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG
        KLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMP+IP VLVNGSEGIGTGWSSYIPNYNPRDII NVRR+L+GE MLPMDPWY+GF+GTIEKTAT+EGG
Subjt:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG

Query:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS
         SYTVSG IEEV DTTLRITELPVRRWTNDYK+FLDSVTRV+ KNDKDKEKAAKDPFIEQADHHSDDK VSIDVHLTEENM+LA+QEGLKKKFKLTTTVS
Subjt:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS

Query:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV
        TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKR LLENLE ELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEV
Subjt:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV

Query:  AGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKAN
        AGASNET+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD L+KELDEMDRNDAQA+EVRKQQR K N
Subjt:  AGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKAN

Query:  NDVKPKISRNAPKAPRNNKKTSNSETVTESMD-TTSSSTTMEVASN-AVKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESS
        ND+KPKISRNAPKAPRN+KKTSNSET+TESMD TTSSSTT EVA+N  VKPKGKAAPRKAPAKK QGKA  L     D D+DDEVLELK RLAAYKLESS
Subjt:  NDVKPKISRNAPKAPRNNKKTSNSETVTESMD-TTSSSTTMEVASN-AVKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESS

Query:  PDRSEVSTMETEVPQVQ-AANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAAKLGQKL
        P+ SEVS METEVP+VQ AA KKEPSKRAAAK KT+AKSAQIS  DDSDD DFEIKEIAPPAAKK  GGGRKA AANAKTTK     KK+EP A+LGQKL
Subjt:  PDRSEVSTMETEVPQVQ-AANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAAKLGQKL

Query:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPVS
        ITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR   EEEEE   AGNEGK MMGSASS  T EEVA    ARGRSQR NRTQVRYVVSDSDSEPV 
Subjt:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPVS

Query:  VDSDFDEEEADFDED
         DSDFD EEA+ DED
Subjt:  VDSDFDEEEADFDED

KAG7018075.1 DNA topoisomerase 2 [Cucurbita argyrosperma subsp. argyrosperma]

0.0e+00

88.65

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Query:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
        MAVEKKRPLQNSNAANVDS P      AGP KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
Subjt:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ

Query:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN
        RDPSMDS+KVVID EQN ISVFNNGDGVPVE+HQEE+VYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R KKYKQVFSDN
Subjt:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN

Query:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE
        MG KSEP ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ F TE PKRYHI+PNE
Subjt:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE

Query:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP
        RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP
Subjt:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP

Query:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
        +FLKNVATKSGIM+SVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGK+SEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
Subjt:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA

Query:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES
        SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+
Subjt:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES

Query:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI
        WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKKIEERKNWLR FE GTHLDQ+EKLIKYSDFVNKELILFS+
Subjt:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI

Query:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
        ADLQRSIPS+VDGLKPGQRKIL    +    K+ K   F               +  ST++ +  DFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
Subjt:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT

Query:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG
        KLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMP+IP VLVNGSEGIGTGWSSYIPNYNPRDII NVRR+L+GE MLPMDPWY+GF+GTIEKTAT+EGG
Subjt:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG

Query:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS
         SYTVSG IEEV DTTLRITELPVRRWTNDYK+FLDSVTRV+ KNDKDKEKAAKDPFIEQADHHSDDK VSIDVHLTEENM+LA+QEGLKKKFKLTTTVS
Subjt:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS

Query:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV
        TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKR LLENLE ELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEV
Subjt:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV

Query:  AGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKAN
        AGASNET+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD L+KELDEMDRNDAQA+EVRKQQR K N
Subjt:  AGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKAN

Query:  NDVKPKISRNAPKAPRNNKKTSNSETVTESMD-TTSSSTTMEVASN-AVKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESS
        ND+KPKISRNAPKAPRN+KKTSNSET+TESMD TTSSSTT EVA+N  VKPKGKAAPRKAPAKK QGKA  L     D D+DDEVLELKDRLAAYKLESS
Subjt:  NDVKPKISRNAPKAPRNNKKTSNSETVTESMD-TTSSSTTMEVASN-AVKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESS

Query:  PDRSEVSTMETEVPQVQ-AANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAAKLGQKL
        P+ SEVS METEVP+VQ AA KKEPSKRAAAKKKT+AKSAQIS  DDSDD DFEIKEIAPPAAKK  GGGRKA AANAKTTK     KK+EP A+LGQKL
Subjt:  PDRSEVSTMETEVPQVQ-AANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAAKLGQKL

Query:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPVS
        ITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR   EEEEE   AGNEGK MMGSASS  T EEVA    ARGRSQR NRTQVRYVVSDSDSEPV 
Subjt:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPVS

Query:  VDSDFDEEEADFDED
         DSDFD EEA+ DED
Subjt:  VDSDFDEEEADFDED

XP_022152631.1 DNA topoisomerase 2 isoform X1 [Momordica charantia]

0.0e+00

89.03

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Query:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
        MAVEKKRPLQNS  ANVDS P      AGP KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
Subjt:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ

Query:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN
        RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEE+VYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVF DN
Subjt:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN

Query:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE
        MG KSEP ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS F TE PKRYHIKPNE
Subjt:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE

Query:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP
        RWEIVVTLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGS CELTP
Subjt:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP

Query:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
        EFLKNVA+KSGIM+SVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG++SEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
Subjt:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA

Query:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES
        SSKQITENKEIQYIKQILGLQQGKEYNN K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKATHRNGTVLSFYTMPEYES
Subjt:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES

Query:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI
        WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDF+WQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFS+
Subjt:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI

Query:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
        ADLQRSIPSVVDGLKPGQRKIL    +    K+ K   F               +  ST++ +  DFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
Subjt:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT

Query:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG
        KLSNVTRFLFP+DDD+LLNYLNEDGQSIEPTWYMP+IP VLVNGSEGIGTGWSSY+PNYNPRDII NV+RLLDGETM+PMDPWYKGF+G IEKTAT+EGG
Subjt:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG

Query:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS
        +SYTVSG IEEV DTTLRITELPVRRWTNDYKEFLDSVTRVA KN  DKEKAAKDPFIEQADHHSDDK VSIDVHLTEENM+LALQEGLKKKFKLTTTVS
Subjt:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS

Query:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV
        TSNMHLFD+NGVIKKYDTPEQILEEFFPLRLE+YEKRK  LLENLE ELL+LENKVRFILAVVNGEI+VSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV
Subjt:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV

Query:  AGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKANN
        AGASNET+E EESPE KGERVSDY YLLALAIGTLTIEKVQELCNDRD+LKGEVEDLRKATPKSLWLKDLD+L+KELDEMDRNDAQAEEVRKQQR KANN
Subjt:  AGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKANN

Query:  DVKPKISRN-APKAPRNNKKTSNSETVTESMDTTSSSTTMEVASNA-VKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESSP
        DVKPKISRN APKAPRN+KKT NSET+ ESMDTTSSSTTMEVASNA VKPKGKAAPRKAPAKK      G + N  D D+DDEVLELKDRLAAYK++SSP
Subjt:  DVKPKISRN-APKAPRNNKKTSNSETVTESMDTTSSSTTMEVASNA-VKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESSP

Query:  DRSEVSTMETEVPQV-QAANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAA-KLGQKL
        DRSEVS METEVPQV  AA KKEPSKRA AKKKT+AKSAQISDNDDSDD+DFEIKE+APPAAKKGGG      AANAKTTKPPAAAKKRE AA KLGQKL
Subjt:  DRSEVSTMETEVPQV-QAANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAA-KLGQKL

Query:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPV-
        ITQML P +N+GISPEKKVRK+RASPFNKKSGS+LGRVGEEEEEE    GNEGK+ MGSA SSET EE AGFLPARGRSQRANRTQV+YV+SDSDS+PV 
Subjt:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPV-

Query:  ---SVDSDFDEEE
             D DFD+E+
Subjt:  ---SVDSDFDEEE

XP_022152632.1 DNA topoisomerase 2 isoform X2 [Momordica charantia]

0.0e+00

88.9

Show/hide

Query:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
        MAVEKKRPLQNS  ANVDS P      AGP KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
Subjt:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ

Query:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN
        RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEE+VYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVF DN
Subjt:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN

Query:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE
        MG KSEP ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS F TE PKRYHIKPNE
Subjt:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE

Query:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP
        RWEIVVTLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGS CELTP
Subjt:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP

Query:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
        EFLKNVA+KSGIM+SVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG++SEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
Subjt:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA

Query:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES
        SSKQITENKEIQYIKQILGLQQGKEYNN K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKATHRNGTVLSFYTMPEYES
Subjt:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES

Query:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI
        WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDF+WQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFS+
Subjt:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI

Query:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
        ADLQRSIPSVVDGLKPGQRKIL    +    K+ K   F               +  ST++ +  DFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
Subjt:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT

Query:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG
        KLSNVTRFLFP+DDD+LLNYLNEDGQSIEPTWYMP+IP VLVNGSEGIGTGWSSY+PNYNPRDII NV+RLLDGETM+PMDPWYKGF+G IEKTAT+EGG
Subjt:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG

Query:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS
        +SYTVSG IEEV DTTLRITELPVRRWTNDYKEFLDSVTRVA KN  DKEKAAKDPFIEQADHHSDDK VSIDVHLTEENM+LALQEGLKKKFKLTTTVS
Subjt:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS

Query:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV
        TSNMHLFD+NGVIKKYDTPEQILEEFFPLRLE+YEKRK  LLENLE ELL+LENKVRFILAVVNGEI+VSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV
Subjt:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV

Query:  AGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKANN
        AGASNET+E EESPE KGERVSDY YLLALAIGTLTIEKVQELCNDRD+LKGEVEDLRKATPKSLWLKDLD+L+KELDEMDRNDAQAEEVRKQQR KANN
Subjt:  AGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKANN

Query:  DVKPKISRN-APKAPRNNKKTSNSETVTESMDTTSSSTTMEVASNA-VKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESSP
        DVKPKISRN APKAPRN+KKT NSET+ ESMDTTSSSTTMEVASNA VKPKGKAAPRKAPAKK      G + N  D D+DDEVLELKDRLAAYK++SSP
Subjt:  DVKPKISRN-APKAPRNNKKTSNSETVTESMDTTSSSTTMEVASNA-VKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESSP

Query:  DRSEVSTMETEVPQV-QAANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAA-KLGQKL
        DRSE   METEVPQV  AA KKEPSKRA AKKKT+AKSAQISDNDDSDD+DFEIKE+APPAAKKGGG      AANAKTTKPPAAAKKRE AA KLGQKL
Subjt:  DRSEVSTMETEVPQV-QAANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAA-KLGQKL

Query:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPV-
        ITQML P +N+GISPEKKVRK+RASPFNKKSGS+LGRVGEEEEEE    GNEGK+ MGSA SSET EE AGFLPARGRSQRANRTQV+YV+SDSDS+PV 
Subjt:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPV-

Query:  ---SVDSDFDEEE
             D DFD+E+
Subjt:  ---SVDSDFDEEE

XP_022935015.1 DNA topoisomerase 2 isoform X1 [Cucurbita moschata]

0.0e+00

88.58

Show/hide

Query:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
        MAVEKKRPLQNSNAANVDS P      AGP KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
Subjt:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ

Query:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN
        RDPSMDS+KVVID EQN ISVFNNGDGVPVE+HQEE+VYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R KKYKQVFSDN
Subjt:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN

Query:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE
        MG KSEP ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ F TE PKRYHI+PNE
Subjt:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE

Query:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP
        RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP
Subjt:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP

Query:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
        +FLKNVATKSGIM+SVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGK+SEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
Subjt:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA

Query:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES
        SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+
Subjt:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES

Query:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI
        WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKKIEERKNWLR FE GTHLDQ+EKLIKYSDFVNKELILFS+
Subjt:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI

Query:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
        ADLQRSIPS+VDGLKPGQRKIL    +    K+ K   F               +  ST++ +  DFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
Subjt:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT

Query:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG
        KLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMP+IP VLVNGSEGIGTGWSSYIPNYNPRDII NVRR+L+GE MLPMDPWY+GF+GTIEKTAT+EGG
Subjt:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG

Query:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS
         SYTVSG IEEV DTTLRITELPVRRWTNDYK+FLDSVTRV+ KNDKDKEKAAKDPFIEQADHHSDDK VSIDVHLTEENM+LA+QEGLKKKFKLTTTVS
Subjt:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS

Query:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV
        TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKR LLENLE ELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEV
Subjt:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV

Query:  AGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKAN
        AGASNET+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD L+KELDEMDRNDAQA+EVRKQQR K N
Subjt:  AGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKAN

Query:  NDVKPKISRNAPKAPRNNKKTSNSETVTESMD-TTSSSTTMEVASN-AVKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESS
        ND+KPKISRNAPKAPRN+KKTSNSET+TESMD TTSSSTT EVA+N  VKPKGKAAPRKAPAKK QGK   L     D D+DDEVLELKDRLAAYKLESS
Subjt:  NDVKPKISRNAPKAPRNNKKTSNSETVTESMD-TTSSSTTMEVASN-AVKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESS

Query:  PDRSEVSTMETEVPQVQ-AANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAAKLGQKL
        P+ SEVS METEVP+VQ AA KKEPSKRAAAKKKT+AKSAQIS  DDSDD DFEIKEIAPPAAKK  GGGRKA AANAKTTK     KK+EP A+LGQKL
Subjt:  PDRSEVSTMETEVPQVQ-AANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAAKLGQKL

Query:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPVS
        ITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR   EEEEE   AGNEGK MMGSASS  T EEVA    ARGRSQR NRTQVRYVVSDSDSEPV 
Subjt:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPVS

Query:  VDSDFDEEEADFDED
         DSDFD EEA+ DED
Subjt:  VDSDFDEEEADFDED

TrEMBL top hits

e value

%identity

Alignment

A0A6J1DGT3 DNA topoisomerase 2

0.0e+00

88.9

Show/hide

Query:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
        MAVEKKRPLQNS  ANVDS P      AGP KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
Subjt:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ

Query:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN
        RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEE+VYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVF DN
Subjt:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN

Query:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE
        MG KSEP ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS F TE PKRYHIKPNE
Subjt:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE

Query:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP
        RWEIVVTLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGS CELTP
Subjt:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP

Query:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
        EFLKNVA+KSGIM+SVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG++SEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
Subjt:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA

Query:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES
        SSKQITENKEIQYIKQILGLQQGKEYNN K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKATHRNGTVLSFYTMPEYES
Subjt:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES

Query:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI
        WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDF+WQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFS+
Subjt:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI

Query:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
        ADLQRSIPSVVDGLKPGQRKIL    +    K+ K   F               +  ST++ +  DFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
Subjt:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT

Query:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG
        KLSNVTRFLFP+DDD+LLNYLNEDGQSIEPTWYMP+IP VLVNGSEGIGTGWSSY+PNYNPRDII NV+RLLDGETM+PMDPWYKGF+G IEKTAT+EGG
Subjt:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG

Query:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS
        +SYTVSG IEEV DTTLRITELPVRRWTNDYKEFLDSVTRVA KN  DKEKAAKDPFIEQADHHSDDK VSIDVHLTEENM+LALQEGLKKKFKLTTTVS
Subjt:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS

Query:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV
        TSNMHLFD+NGVIKKYDTPEQILEEFFPLRLE+YEKRK  LLENLE ELL+LENKVRFILAVVNGEI+VSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV
Subjt:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV

Query:  AGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKANN
        AGASNET+E EESPE KGERVSDY YLLALAIGTLTIEKVQELCNDRD+LKGEVEDLRKATPKSLWLKDLD+L+KELDEMDRNDAQAEEVRKQQR KANN
Subjt:  AGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKANN

Query:  DVKPKISRN-APKAPRNNKKTSNSETVTESMDTTSSSTTMEVASNA-VKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESSP
        DVKPKISRN APKAPRN+KKT NSET+ ESMDTTSSSTTMEVASNA VKPKGKAAPRKAPAKK      G + N  D D+DDEVLELKDRLAAYK++SSP
Subjt:  DVKPKISRN-APKAPRNNKKTSNSETVTESMDTTSSSTTMEVASNA-VKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESSP

Query:  DRSEVSTMETEVPQV-QAANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAA-KLGQKL
        DRSE   METEVPQV  AA KKEPSKRA AKKKT+AKSAQISDNDDSDD+DFEIKE+APPAAKKGGG      AANAKTTKPPAAAKKRE AA KLGQKL
Subjt:  DRSEVSTMETEVPQV-QAANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAA-KLGQKL

Query:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPV-
        ITQML P +N+GISPEKKVRK+RASPFNKKSGS+LGRVGEEEEEE    GNEGK+ MGSA SSET EE AGFLPARGRSQRANRTQV+YV+SDSDS+PV 
Subjt:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPV-

Query:  ---SVDSDFDEEE
             D DFD+E+
Subjt:  ---SVDSDFDEEE

A0A6J1DIB5 DNA topoisomerase 2

0.0e+00

89.03

Show/hide

Query:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
        MAVEKKRPLQNS  ANVDS P      AGP KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
Subjt:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ

Query:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN
        RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEE+VYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVF DN
Subjt:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN

Query:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE
        MG KSEP ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS F TE PKRYHIKPNE
Subjt:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE

Query:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP
        RWEIVVTLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGS CELTP
Subjt:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP

Query:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
        EFLKNVA+KSGIM+SVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG++SEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
Subjt:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA

Query:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES
        SSKQITENKEIQYIKQILGLQQGKEYNN K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKATHRNGTVLSFYTMPEYES
Subjt:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES

Query:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI
        WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDF+WQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFS+
Subjt:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI

Query:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
        ADLQRSIPSVVDGLKPGQRKIL    +    K+ K   F               +  ST++ +  DFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
Subjt:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT

Query:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG
        KLSNVTRFLFP+DDD+LLNYLNEDGQSIEPTWYMP+IP VLVNGSEGIGTGWSSY+PNYNPRDII NV+RLLDGETM+PMDPWYKGF+G IEKTAT+EGG
Subjt:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG

Query:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS
        +SYTVSG IEEV DTTLRITELPVRRWTNDYKEFLDSVTRVA KN  DKEKAAKDPFIEQADHHSDDK VSIDVHLTEENM+LALQEGLKKKFKLTTTVS
Subjt:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS

Query:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV
        TSNMHLFD+NGVIKKYDTPEQILEEFFPLRLE+YEKRK  LLENLE ELL+LENKVRFILAVVNGEI+VSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV
Subjt:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV

Query:  AGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKANN
        AGASNET+E EESPE KGERVSDY YLLALAIGTLTIEKVQELCNDRD+LKGEVEDLRKATPKSLWLKDLD+L+KELDEMDRNDAQAEEVRKQQR KANN
Subjt:  AGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKANN

Query:  DVKPKISRN-APKAPRNNKKTSNSETVTESMDTTSSSTTMEVASNA-VKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESSP
        DVKPKISRN APKAPRN+KKT NSET+ ESMDTTSSSTTMEVASNA VKPKGKAAPRKAPAKK      G + N  D D+DDEVLELKDRLAAYK++SSP
Subjt:  DVKPKISRN-APKAPRNNKKTSNSETVTESMDTTSSSTTMEVASNA-VKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESSP

Query:  DRSEVSTMETEVPQV-QAANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAA-KLGQKL
        DRSEVS METEVPQV  AA KKEPSKRA AKKKT+AKSAQISDNDDSDD+DFEIKE+APPAAKKGGG      AANAKTTKPPAAAKKRE AA KLGQKL
Subjt:  DRSEVSTMETEVPQV-QAANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAA-KLGQKL

Query:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPV-
        ITQML P +N+GISPEKKVRK+RASPFNKKSGS+LGRVGEEEEEE    GNEGK+ MGSA SSET EE AGFLPARGRSQRANRTQV+YV+SDSDS+PV 
Subjt:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPV-

Query:  ---SVDSDFDEEE
             D DFD+E+
Subjt:  ---SVDSDFDEEE

A0A6J1F3D6 DNA topoisomerase 2

0.0e+00

88.51

Show/hide

Query:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
        MAVEKKRPLQNSNAANVDS P      AGP KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
Subjt:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ

Query:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN
        RDPSMDS+KVVID EQN ISVFNNGDGVPVE+HQEE+VYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R KKYKQVFSDN
Subjt:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN

Query:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE
        MG KSEP ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ F TE PKRYHI+PNE
Subjt:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE

Query:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP
        RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP
Subjt:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP

Query:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
        +FLKNVATKSGIM+SVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGK+SEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
Subjt:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA

Query:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES
        SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+
Subjt:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES

Query:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI
        WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKKIEERKNWLR FE GTHLDQ+EKLIKYSDFVNKELILFS+
Subjt:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI

Query:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
        ADLQRSIPS+VDGLKPGQRKIL    +    K+ K   F               +  ST++ +  DFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
Subjt:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT

Query:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG
        KLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMP+IP VLVNGSEGIGTGWSSYIPNYNPRDII NVRR+L+GE MLPMDPWY+GF+GTIEKTAT+EGG
Subjt:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG

Query:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS
         SYTVSG IEEV DTTLRITELPVRRWTNDYK+FLDSVTRV+ KNDKDKEKAAKDPFIEQADHHSDDK VSIDVHLTEENM+LA+QEGLKKKFKLTTTVS
Subjt:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS

Query:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV
        TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKR LLENLE ELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEV
Subjt:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV

Query:  AGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKAN
        AGASNET+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD L+KELDEMDRNDAQA+EVRKQQR K N
Subjt:  AGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKAN

Query:  NDVKPKISRNAPKAPRNNKKTSNSETVTESMD-TTSSSTTMEVASN-AVKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESS
        ND+KPKISRNAPKAPRN+KKTSNSET+TESMD TTSSSTT EVA+N  VKPKGKAAPRKAPAKK  GK   L     D D+DDEVLELKDRLAAYKLESS
Subjt:  NDVKPKISRNAPKAPRNNKKTSNSETVTESMD-TTSSSTTMEVASN-AVKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESS

Query:  PDRSEVSTMETEVPQVQ-AANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAAKLGQKL
        P+ SEVS METEVP+VQ AA KKEPSKRAAAKKKT+AKSAQIS  DDSDD DFEIKEIAPPAAKK  GGGRKA AANAKTTK     KK+EP A+LGQKL
Subjt:  PDRSEVSTMETEVPQVQ-AANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAAKLGQKL

Query:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPVS
        ITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR   EEEEE   AGNEGK MMGSASS  T EEVA    ARGRSQR NRTQVRYVVSDSDSEPV 
Subjt:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPVS

Query:  VDSDFDEEEADFDED
         DSDFD EEA+ DED
Subjt:  VDSDFDEEEADFDED

A0A6J1F9E0 DNA topoisomerase 2

0.0e+00

88.58

Show/hide

Query:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
        MAVEKKRPLQNSNAANVDS P      AGP KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
Subjt:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ

Query:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN
        RDPSMDS+KVVID EQN ISVFNNGDGVPVE+HQEE+VYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R KKYKQVFSDN
Subjt:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN

Query:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE
        MG KSEP ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ F TE PKRYHI+PNE
Subjt:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE

Query:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP
        RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP
Subjt:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP

Query:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
        +FLKNVATKSGIM+SVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGK+SEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
Subjt:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA

Query:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES
        SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+
Subjt:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES

Query:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI
        WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKKIEERKNWLR FE GTHLDQ+EKLIKYSDFVNKELILFS+
Subjt:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI

Query:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
        ADLQRSIPS+VDGLKPGQRKIL    +    K+ K   F               +  ST++ +  DFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
Subjt:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT

Query:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG
        KLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMP+IP VLVNGSEGIGTGWSSYIPNYNPRDII NVRR+L+GE MLPMDPWY+GF+GTIEKTAT+EGG
Subjt:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG

Query:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS
         SYTVSG IEEV DTTLRITELPVRRWTNDYK+FLDSVTRV+ KNDKDKEKAAKDPFIEQADHHSDDK VSIDVHLTEENM+LA+QEGLKKKFKLTTTVS
Subjt:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS

Query:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV
        TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKR LLENLE ELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEV
Subjt:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV

Query:  AGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKAN
        AGASNET+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD L+KELDEMDRNDAQA+EVRKQQR K N
Subjt:  AGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKAN

Query:  NDVKPKISRNAPKAPRNNKKTSNSETVTESMD-TTSSSTTMEVASN-AVKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESS
        ND+KPKISRNAPKAPRN+KKTSNSET+TESMD TTSSSTT EVA+N  VKPKGKAAPRKAPAKK QGK   L     D D+DDEVLELKDRLAAYKLESS
Subjt:  NDVKPKISRNAPKAPRNNKKTSNSETVTESMD-TTSSSTTMEVASN-AVKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESS

Query:  PDRSEVSTMETEVPQVQ-AANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAAKLGQKL
        P+ SEVS METEVP+VQ AA KKEPSKRAAAKKKT+AKSAQIS  DDSDD DFEIKEIAPPAAKK  GGGRKA AANAKTTK     KK+EP A+LGQKL
Subjt:  PDRSEVSTMETEVPQVQ-AANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAAKLGQKL

Query:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPVS
        ITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR   EEEEE   AGNEGK MMGSASS  T EEVA    ARGRSQR NRTQVRYVVSDSDSEPV 
Subjt:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPVS

Query:  VDSDFDEEEADFDED
         DSDFD EEA+ DED
Subjt:  VDSDFDEEEADFDED

A0A6J1IWX9 DNA topoisomerase 2

0.0e+00

88.65

Show/hide

Query:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
        MAVE KRPLQNSNAANVDS P      AGP KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLW+YENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ
Subjt:  MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQ

Query:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN
        RDPSMDS+KVVID EQNCISVFNNGDGVPVE+HQEE+VYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R KKYKQVFSDN
Subjt:  RDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDN

Query:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE
        MG KSEP ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ F TE PKRYHI+PNE
Subjt:  MGNKSEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNE

Query:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP
        RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP
Subjt:  RWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP

Query:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
        +FLKNVATKSGIM+SVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGK+SEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
Subjt:  EFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA

Query:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES
        SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+
Subjt:  SSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES

Query:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI
        WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKKIEERKNWLR FE GTHLDQ+EKLIKYSDFVNKELILFS+
Subjt:  WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSI

Query:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
        ADLQRSIPS+VDGLKPGQRKIL    +    K+ K   F               +  ST++ +  DFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
Subjt:  ADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNF-------------RVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT

Query:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG
        KLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMP+IP VLVNGSEGIGTGWSSYIPNYNPRDII NVRR+LDGE MLPMDPWY+GF+GTIEKTAT+EGG
Subjt:  KLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGG

Query:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS
         SYTVSG IEEV DTTLRITELPVRRWTNDYK+FLDSVTRV+ KNDKDKEKAAKDPFIEQADHHSDDK VSI+VHLTEENM+LA+QEGLKKKFKLTTTVS
Subjt:  ISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVS

Query:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV
        TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKR LLENLE ELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEV
Subjt:  TSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEV

Query:  AGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKAN
        AGASNET+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE+LRKATPKSLWLKDLD L+KELDEMDRNDAQA+EVRKQQR K N
Subjt:  AGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKAN

Query:  NDVKPKISRNAPKAPRNNKKTSNSETVTESMD-TTSSSTTMEVASN-AVKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESS
        ND+KPKISRNAPKAPRN+KKTSNSET+TESMD  TSSSTT EVA+N  VKPKGKAAPRKAPAKK QGKA  L     D D DDEVLELKDRLAAYKLESS
Subjt:  NDVKPKISRNAPKAPRNNKKTSNSETVTESMD-TTSSSTTMEVASN-AVKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESS

Query:  PDRSEVSTMETEVPQVQ-AANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAAKLGQKL
        P+ SEVS METEVP+VQ AA KKEPSKRAAAKKKT+AKSAQIS  DDSDD DFEIKEIAPPAAKK  GGGRKA AANAKTTK     KK+EP A+LGQKL
Subjt:  PDRSEVSTMETEVPQVQ-AANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAAKLGQKL

Query:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPVS
        ITQMLEP ENSGISPEKKVRKIR SPFNKKSGSVLGR   EEEEE   AGNEGK MMGSASS  T EEVA    ARGRSQR NRTQVRYVVSDSDSEPV 
Subjt:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPVS

Query:  VDSDFDEEEADFDED
         DSDFD EEAD DED
Subjt:  VDSDFDEEEADFDED

SwissProt top hits

e value

%identity

Alignment

O24308 DNA topoisomerase 2

0.0e+00

62.01

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Query:  KKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPS
        +KRPLQ SNAAN+            P+KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHR+V+YVPGLYKIFDEILVNAADNKQRDPS
Subjt:  KKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPS

Query:  MDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDNMGNK
        MDS+KV ID E N +SV+NNGDGVPVEIHQEE+VYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADG+R KKYKQVFS+NMG K
Subjt:  MDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDNMGNK

Query:  SEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNERWEI
         EP ITKCK  +NWTKVTFKPDL KF M +LE+DVVALMKKRVLD+AGC GKTVKVELNG  +  KSF+DY DL+LK A         R H K  +RWEI
Subjt:  SEPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNERWEI

Query:  VVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLK
         ++LS+GQFQQVSFVN IATIKGGTHVDYITNQI  Y+MN VNKK K+ANVKAH VK++LWVF+N+LIDNPAFDSQTKETLT RQ+SFGS C++    LK
Subjt:  VVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLK

Query:  NVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ
        +V  KSGI++++LSW +FKQSKDLKKTDG KT+++ G  K EDAN AGG++SEKCTLILTEGDSAKALAMAGL VVGRD YGVFPLRGKLLNVREASSKQ
Subjt:  NVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ

Query:  ITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKES
        I +N+EIQ IK+ILGLQQ KEY N K+LRYGHLMIM DQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEF TP+++A+H N T+ SFY+MPEYE+WKE 
Subjt:  ITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKES

Query:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSIADLQ
        L  +A+ W IKYYKGLGTST +EGREYF  LG+H+KDFIW D+ DG AIELAFSKKK E RK W+R+FEPGT  D   KLI Y DFVNKELILFS ADL 
Subjt:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSIADLQ

Query:  RSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNFRVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKL
         S        K   ++I      G +S+   + +   +  ST++ +  DFVGSNNINLL PNGQFGT N GGKDHAS+RYIYT+LS VTR LF + DDKL
Subjt:  RSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNFRVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKL

Query:  LNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGGISYTVSGTIEEVCDTTL
        L YLNEDG+SIEP WYMP+IP+VLVNGSEGIGTGWSSYIPNYNPR+IIANVRRLL+GE ++PMDPWYKGF GTIEK+A +EGG  Y V+GT+ E+ + T 
Subjt:  LNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGGISYTVSGTIEEVCDTTL

Query:  RITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYD
        RITELP+R+WT DYK+FL+S+T        D     KDP IE    + DD IV I++ +  E +   LQEGL KKFKLT+T+STSNMHLFDA G  KK+D
Subjt:  RITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYD

Query:  TPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPE--
        TPEQILEEFFPLRL++YEK K  +L NL   LL L+NKVRFIL VVNGEIIVSNR++ +L  EL+ KGFTP P+K KS +P+VAGA+++  E +E  E  
Subjt:  TPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPE--

Query:  -------VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKANNDVKPKISR
               V+G    DY+ LL+L IGTLT+E VQ+L +++ + + E E L      SLWLKDLD  +K+LDE+D   A+ +  R  Q SK  N    K ++
Subjt:  -------VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKANNDVKPKISR

Query:  NAPKAPRNNKKTSNSETVTESMDTTSSSTTMEVASNA--VKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESSPDRSEVSTM
          P+  +N KK  + E   ++  +      +E A  A   KPKG+AAP+K   K+P                +D++  L++RLAAY +ESS ++S+   M
Subjt:  NAPKAPRNNKKTSNSETVTESMDTTSSSTTMEVASNA--VKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESSPDRSEVSTM

Query:  ETEVPQVQAANKKEPSKRAAAKKKTSA------KSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAK------TTKPPAAAKKREPAAK--L
        E+E  Q +AA KK+ +KR  AKKK+S          +++D DD DD+  E+++ A P  K    GGRK  A NAK        K PAA KKR    K   
Subjt:  ETEVPQVQAANKKEPSKRAAAKKKTSA------KSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAK------TTKPPAAAKKREPAAK--L

Query:  GQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDS
        GQKL+T ML+PAE +G SPEKKVRK+R SPFNKKSGS+LGR    ++    A  + G       S  E  E      PAR R QRANRTQ++Y +S+S+S
Subjt:  GQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDS

Query:  EPVSVDSDFDEEEADFDED
        E    DSD D E +DF+ED
Subjt:  EPVSVDSDFDEEEADFDED

O46374 DNA topoisomerase 2-alpha

1.5e-312

45.57

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Query:  TIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMV-HRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVE
        +IE +YQKKTQLEHILLRPDTY+GS+E  TQ +WVY+ D  + +R VT+VPGLYKIFDEILVNAADNKQRDP M  ++V ID E N IS++NNG G+PV 
Subjt:  TIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMV-HRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVE

Query:  IHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDNMGNKSEPTITKCKEGDNWTKVTFKPDLAKFN
         H+ E++YVP LIFG LLTSSNYDD EKK TGGRNGYGAKL NIFST+F +ETA  + +K +KQ + DNMG   E  + K   G+++T +TF PDL+KF 
Subjt:  IHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDNMGNKSEPTITKCKEGDNWTKVTFKPDLAKFN

Query:  MTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTH
        M  L+ D+VALM +R  D+AG   K VKV LNG ++PVK F+ YVDLYLK      T NP K  H + N RWE+ +T+SE  FQQ+SFVN IAT KGG H
Subjt:  MTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTH

Query:  VDYITNQIANYVMNVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNVATKSGIMESVLSWVNFKQSKDL-
        VDY+ +QI   +++VV KKNK    VKAH VK+++W+F+NALI+NP FDSQTKE +T++  SFGS C+L+ +F+K  A   GI+ES+L+WV FK    L 
Subjt:  VDYITNQIANYVMNVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNVATKSGIMESVLSWVNFKQSKDL-

Query:  KKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY--
        KK    K  +I GI KL+DAN AGG++S +CTLILTEGDSAK LA++GLGVVGRD YGVFPLRGK+LNVREAS KQI EN EI  I +I+GLQ  K Y  
Subjt:  KKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY--

Query:  -NNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTS
         ++ K LRYG +MIMTDQD DGSHIKGLLINFIH  WPSLL+   FL EFITPIVK + +N   ++FY++PE+E WK S   N   W +KYYKGLGTSTS
Subjt:  -NNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTS

Query:  KEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFE-----------PGTHL-DQTEKLIKYSDFVNKELILFSIADLQRSIPSVVDG
        KE +EYF  + +H+  F +    D  AI LAFSKK+I++RK WL HF            P  +L  QT   + Y+DF+NKELILFS +D +RSIPS+VDG
Subjt:  KEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFE-----------PGTHL-DQTEKLIKYSDFVNKELILFSIADLQRSIPSVVDG

Query:  LKPGQRKILSVLSR-------------GTLSKKQKFLNFRVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKD
        LKPGQRK+L    +             G++++   + +  ++ + T++ +  +FVGSNN+NLL P GQFGTR HGGKD AS RYI+T LS + R LFP  
Subjt:  LKPGQRKILSVLSR-------------GTLSKKQKFLNFRVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKD

Query:  DDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGGISYTVSGTIEEVC
        DD  L +L +D Q +EP WY+P+IPMVL+NG+EGIGTGWS  IPN++ R+++ N+R L+DGE  LPM P YK F GTIE+ A  +    Y +SG +  + 
Subjt:  DDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGGISYTVSGTIEEVC

Query:  DTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVSTSNMHLFDANGVI
         TT+ I+ELP+R WT  YKE      +V        EK    P I     +  D  V   V +TEE +  A + GL K FKL T+++ ++M LFD  G +
Subjt:  DTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVSTSNMHLFDANGVI

Query:  KKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKT-KSVEPEVAGASNETEETEE
        KKYDT   IL +FF LRL++Y  RK  LL  L  E  KL N+ RFIL  ++G+II+ N+ + +L   L  +G+   P K  K  + +V       E   E
Subjt:  KKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKT-KSVEPEVAGASNETEETEE

Query:  SPEVKGERVSD----YEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEV-------RKQQRSKANND
            K + V+D    + YLL + +  LT EK  ELC  R++ + E+E L++ +P  LW +DL +  +EL+ ++  + Q E++       + + +     +
Subjt:  SPEVKGERVSD----YEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEV-------RKQQRSKANND

Query:  VKPK------ISRNAPKAPRNNKKTSNSETVTESMDTTSSSTTMEVASNAVKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLE
        V P       I R   +     +K    +  +E+ + +     MEV    +K + +   ++ P  K + +                 L  K    A K  
Subjt:  VKPK------ISRNAPKAPRNNKKTSNSETVTESMDTTSSSTTMEVASNAVKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLE

Query:  S-SPDRSEVSTMET--EVPQVQAANKKEPSKRAAAKKKTSAKSAQISDNDDSD----DEDFEIKEIAP-------------PAAKKGGGGGRKANAANAK
          S   S++S+ E+   VP      +KEP +RAAAK K +       D  D+D    DEDF   + +P             P  +K        +A +AK
Subjt:  S-SPDRSEVSTMET--EVPQVQAANKKEPSKRAAAKKKTSAKSAQISDNDDSD----DEDFEIKEIAP-------------PAAKKGGGGGRKANAANAK

Query:  TTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRAS
           PP+ +    P A      +T+ ++P     ++ +K   K ++S
Subjt:  TTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRAS

P08096 DNA topoisomerase 2

0.0e+00

45.34

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Query:  IEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVY--ENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVE
        +   YQ+ T  EH+L RPDTY+GSIE  T  +WV+  E +K+ +++VTYVPGLYKIFDEI+VNAADNK RDP+M+++KV +D E N IS++NNG G+P+E
Subjt:  IEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVY--ENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVE

Query:  IHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDNMGNKSEPTITKCKEGDNWTKVTFKPDLAKFN
        IH +E++Y+PELIFG+LLTSSNYDD +KK TGGRNGYGAKL NIFSTEFV+ETAD +R KKYKQ + DNM  KSEP IT  K+ D +TK+TFKPDLAKF 
Subjt:  IHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDNMGNKSEPTITKCKEGDNWTKVTFKPDLAKFN

Query:  MTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHV
        M  ++DD+V+++K+R+ D+AG + +T KV LN +R+ +  F+ YV++YL S +    E P+  +   N+RW++   +S+GQF+QVSFVN I+TI+GGTHV
Subjt:  MTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHV

Query:  DYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNVATKSGIMESVLSWVNFKQSKDLKKT
        +Y+ N+I + +  VV K+NK A VKA  +K+Y+ VF+N  I+NP+FDSQTKETLT + S+FGS C L+ +FLK +  KS ++E VL +   K  + L K 
Subjt:  DYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNVATKSGIMESVLSWVNFKQSKDLKKT

Query:  DGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNAKA
        DG    +I+G+ KLEDAN AG K S KC LILTEGDSAK+LA++GL VVGRD+YGVFPLRGKLLNVREAS  QI  NKEIQ IK+I+G    K Y + K 
Subjt:  DGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNAKA

Query:  LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREY
        LRYGHLMIMTDQDHDGSHIKGL+IN++ S +PSLL++P FL++FITPI+K T R   V +FYT+PEYE WKE+   N  GW IKYYKGLGTS   + + Y
Subjt:  LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREY

Query:  FEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSIADLQRSIPSVVDGLKPGQRKIL---------
        F  L +H K F    + D E IE+AF+KKK + RK WLR + PG ++D T+  I   DF+N+ELI FS+AD  RSIPSVVDGLKPGQRK++         
Subjt:  FEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSIADLQRSIPSVVDGLKPGQRKIL---------

Query:  --SVLSR--GTLSKKQKFLNFRVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPT
          + +SR  G ++ +  + +  V+   T++ +  +FVGSNNINLL+PNGQFGTR+ GGK+ ++SRY+ T LS + R LF  +DD+LLNY N++GQ IEP 
Subjt:  --SVLSR--GTLSKKQKFLNFRVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPT

Query:  WYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGGISYTVSGTIEEVCDTTLRITELPVRRWTNDY
        +Y+P++PMVLVNG+EGIGTGWS++IPNYNP+DI AN+R +L+GE +  M PWY+GF G+I K A       Y +SG I ++ +  + ITELP+R WT D 
Subjt:  WYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGGISYTVSGTIEEVCDTTLRITELPVRRWTNDY

Query:  KEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRL
        KE+L++            EK  K  FI   + H  +  V  +V LTE  M  AL E L+ KFKL+ T +TSNM  FDA+G IKKYD+ E IL EF+ +RL
Subjt:  KEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRL

Query:  EFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPF--PKKTKSVEPEVAGASNETEETEESPEVKGERVSD-YEYLL
          Y++RK  ++  LE    +  N+ RFI  ++ GE++VS +++ DL  EL+ K F P   PKK   V+ EV    N   E E+S +V  +  SD Y YLL
Subjt:  EFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPF--PKKTKSVEPEVAGASNETEETEESPEVKGERVSD-YEYLL

Query:  ALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKANNDVKPKISRNAPKAPRNNKKTSNSETVTE
        ++ + +LT E+  EL   +D++  E++ L K TPK LWL DLD+ +   +++  +D Q E + ++Q S+                 R  KK     T T 
Subjt:  ALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKANNDVKPKISRNAPKAPRNNKKTSNSETVTE

Query:  SMDTTSSSTTMEVASNAVKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESSPDRSEVSTMETEVPQVQAANKKEPSKRAAAK
             + S+    +S AVK +  +  + +   + Q                     L +  A+ + E S D + V T +       +  +   SK     
Subjt:  SMDTTSSSTTMEVASNAVKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESSPDRSEVSTMETEVPQVQAANKKEPSKRAAAK

Query:  KKTSAKSAQISDNDDSDDEDFE--IKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKK
           S KS + S + DS+D   +  +K+IA  A+    G GRK N   A T           P++ L    IT     A+N G                KK
Subjt:  KKTSAKSAQISDNDDSDDEDFE--IKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKK

Query:  SGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVV-----SDSDSEPVSVDSDF----DEEEADFDE
        + SV  +  E+++++    G+       S++++E  E+     P R R  R     V+  +      DS  EP   D  F    DE+  D+DE
Subjt:  SGSVLGRVGEEEEEEEAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVV-----SDSDSEPVSVDSDF----DEEEADFDE

P30182 DNA topoisomerase 2

0.0e+00

61.41

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Query:  KRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSM
        K PLQNSNAANV   PA   A AG  KTIEEMYQKK+QLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R VTYVPGLYKIFDEILVNAADNKQRD  M
Subjt:  KRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSM

Query:  DSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDNMGNKS
        DSV+VVIDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADGKR KKYKQVF +NMG KS
Subjt:  DSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDNMGNKS

Query:  EPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENP-KRYHIKPNERWEI
        EP ITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+   TE+P  R   K N+RWE+
Subjt:  EPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENP-KRYHIKPNERWEI

Query:  VVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLK
         V+LSEGQFQQVSFVN IATIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWVF+NALIDNPAFDSQTKETLT+RQSSFGS CEL+ +FLK
Subjt:  VVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLK

Query:  NVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ
         V  KSG++E++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGK+S  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ Q
Subjt:  NVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ

Query:  ITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWK
        IT NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WK
Subjt:  ITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWK

Query:  ESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSIAD
        ESL+GNA+GW IKYYKGLGTST++EG+EYF  LG HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ +  + YSDFVNKELILFS+AD
Subjt:  ESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSIAD

Query:  LQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNFRVTYLSTLL---------------IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTK
        LQRSIPS+VDGLKPGQRKIL V  +    K+ K     V Y+S L                +  D+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TK
Subjt:  LQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNFRVTYLSTLL---------------IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTK

Query:  LSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGGI
        LS VTR LFPKDDD LL+YLNEDGQ IEPTWYMP+IP VLVNG+EGIGTGWS++IPNYNPR+I+ANVRRLL+GE+M+PMDPWY+GF GTIEKTA++EGG 
Subjt:  LSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGGI

Query:  SYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVST
        +YT++G  EEV +TT+RITELP+RRW +DYK FL S+     K D         PF +    ++D+K V  D+ L+EENM+ A QEG  KKFKLTTT++T
Subjt:  SYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVST

Query:  SNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVA
        SNMHLFD  GVIKKY TPEQILEEFF LR E+YEKRK T+++N+E+ELLKLENK RFILAV++GEIIV+ R++ D+  +L+ KGFTPFP+K +SVE  +A
Subjt:  SNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVA

Query:  G-----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEV--RK
        G     A+ E EE    PE     +  S+Y+YLLA+AI +LTIEKV+EL  DRDK+   V D++K TPKSLWL DL+SLDKEL+++D  DAQ ++     
Subjt:  G-----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEV--RK

Query:  QQRSKANNDVKPKISRNAPKAP---RNNKKTSNSETVTESMDTTSSSTTMEVASNAVKPKGKAAPRK---------------------APAKKPQGKAGG
        Q++ +A +    K+ R APK P   +  KK S SET   S    S+  T    +  VKPK +   +K                     A   KP+G+ G 
Subjt:  QQRSKANNDVKPKISRNAPKAP---RNNKKTSNSETVTESMDTTSSSTTMEVASNAVKPKGKAAPRK---------------------APAKKPQGKAGG

Query:  LLNNDGDVD--EDDEVLELKDRLAAYKLESSPDRSEVSTMETEVPQVQAANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGG
                   E+DE+L+L  RLA Y   S+P                           A   KT+  S  I+ +DD DD    + E+AP   KKGG   
Subjt:  LLNNDGDVD--EDDEVLELKDRLAAYKLESSPDRSEVSTMETEVPQVQAANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGG

Query:  RKANAANAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEE--EAAAGNEGKLMMGSASSSETTEE
             A  K  KPPAA +KR        +++          G+SPEKKVRK+R+SPFNKKS SV+ R+ + +EEE  E  AGN             ++E+
Subjt:  RKANAANAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEE--EAAAGNEGKLMMGSASSSETTEE

Query:  VAGFLPARGRSQRANRTQVRYVVSDSDSEPVSVDSDFDEEEADFDED
          G + A  R QRANR ++ YV+SDS+SE  + DS+FD+ E D D++
Subjt:  VAGFLPARGRSQRANRTQVRYVVSDSDSEPVSVDSDFDEEEADFDED

Q55BP5 Probable DNA topoisomerase 2

0.0e+00

45.66

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Query:  KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVE
        K+IEE+YQKK  L+ ILLRPDTY+GS E+  + LWV+E+ +MVHR V++VPG+YKIFDEILVNAADNKQR+ +M  +KVVID E+  ISV N+G G+P++
Subjt:  KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVE

Query:  IHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDNMGNKSEPTITKCKEGDNWTKVTFKPDLAKFN
        +H E ++Y+PELIFG+LLTSS+YDD+EK+ TGGRNG+GAKL NIFST+F++E AD K +K YKQ F++NM +K +P IT  +   ++TK+TF P+L +F 
Subjt:  IHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDNMGNKSEPTITKCKEGDNWTKVTFKPDLAKFN

Query:  MTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTEN--PKRYHIKPNERWEIVVTLS-EGQFQQVSFVNGIATIKGG
        M   +DD+VAL+ KRV D+AGC   T+KV LN + + ++SF+ Y++LY      FP E   PK Y+ K ++RWE+ VTLS E QF QVSFVN I T+KGG
Subjt:  MTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTEN--PKRYHIKPNERWEIVVTLS-EGQFQQVSFVNGIATIKGG

Query:  THVDYITNQIANYVMNVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNVA-TKSGIMESVLSWVNFKQSK
        THV +  + I   +   VNKKNK +A++K   +K++L VF+N LI+NP FDSQTKETLT + SSFGS CE + +F+K V  +KSGI+ S+L +  FK   
Subjt:  THVDYITNQIANYVMNVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNVA-TKSGIMESVLSWVNFKQSK

Query:  DLKK--TDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGK
         LK+  + G K  K+S I KL+DAN AGG  SE CTLILTEGDSAK+LA AG+ VVG+D YG FPL+GKLLNVR+ S+K +  N EI  I  ILGL+ GK
Subjt:  DLKK--TDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGK

Query:  EYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTST
         Y     LRYGHLMIMTDQDHDGSHIKGL+IN +H FWP+LL++P FLVEFITPIVK    N   +SFYTMPE+  W+E+   N  GW +KYYKGLGTST
Subjt:  EYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTST

Query:  SKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQ-TEKLIKYSDFVNKELILFSIADLQRSIPSVVDGLKPGQRKIL-
          EG+EYF  L +HK DF W D+   + IELAFSK + ++RK W+     GT L+Q   K + YSDF+NKEL+LFSIAD +RSIP++VDGLK   RK L 
Subjt:  SKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQ-TEKLIKYSDFVNKELILFSIADLQRSIPSVVDGLKPGQRKIL-

Query:  SVLSR------------GTLSKKQKFLNFRVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNE
        S   R            G +S+   + +   +  ST++ +  +FVGSNNINLL P G +GTR  GGKD +S+RYI+T+L+++ R ++  DDD +L+ + +
Subjt:  SVLSR------------GTLSKKQKFLNFRVTYLSTLL-IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNE

Query:  DGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIE-KTATREGGISYTVSGTIEEVCDTTLRITEL
        DG+ ++P +Y+PVIPM+LVNG  GIGTGWSS IPNYNPRD+I N+R  +DG+ + P+ PWY+GF G+IE    ++  G  Y   G  +++ D    ITEL
Subjt:  DGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIE-KTATREGGISYTVSGTIEEVCDTTLRITEL

Query:  PVRRWTNDYKEFLDSV----TRVAAKNDKDKEKA------AKDPFIEQADHHSDD----KIVSIDV------------HLTEENMMLALQEGLKKKFKLT
        P+  WT DY+E LD +    TR   K +K+K+ A      AK    +++    DD    K+    V            H   + +    +  ++K FKL 
Subjt:  PVRRWTNDYKEFLDSV----TRVAAKNDKDKEKA------AKDPFIEQADHHSDD----KIVSIDV------------HLTEENMMLALQEGLKKKFKLT

Query:  TTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPF-------
        +T++ +NM +FD  G I+++ T   + E FFPLR++ Y+ RK  L E L  E  +L NK RFILAVVN E+++SN ++VDL ++L+   F          
Subjt:  TTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPF-------

Query:  -----PKKTKSVEPEVAGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRND
              KK K+   E   A +  EE + + E + +    Y+YLL+L + +LT+E+V++L  +RD  K E + L     + ++ +DLD+L+K LD+ D  D
Subjt:  -----PKKTKSVEPEVAGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRND

Query:  A----QAEEVRKQQRSKA---NNDVKPKISRNAPKAPRNN--KKTSNSETVTESM----------DTTSSSTTMEVASNAVKPKGKAAPRKAPAKKPQGK
             Q E ++K+ ++KA      +  K+ ++  +AP     K T    T T+S           DTTS+ST+   +SN  KP      ++     P  K
Subjt:  A----QAEEVRKQQRSKA---NNDVKPKISRNAPKAPRNN--KKTSNSETVTESM----------DTTSSSTTMEVASNAVKPKGKAAPRKAPAKKPQGK

Query:  AGGLLNNDGDVD-EDDEVLELKDRLAAYKLESSPDRSEVSTMETEVPQVQAANKKEPSKRA----------AAKKKTSAKSAQISDNDDSDDE
           L++ D D D +DD V+  K +    K     + S+ S  E++    Q ++ + P KR+          A KK T++KS ++ D+  SDDE
Subjt:  AGGLLNNDGDVD-EDDEVLELKDRLAAYKLESSPDRSEVSTMETEVPQVQAANKKEPSKRA----------AAKKKTSAKSAQISDNDDSDDE

Arabidopsis top hits

e value

%identity

Alignment

AT3G10270.1 DNA GYRASE B1

1.4e-24

24.38

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Query:  LQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQ----LEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPS
        L   NA +  SF +S       + T ++   +  Q    L+ +  RP  Y+GS                     T   GL+ +  EIL NA D  Q    
Subjt:  LQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQ----LEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPS

Query:  MDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFSTEF-VIETADGKR-QKKYKQVFSDN
           + VV+  + + +S+ +NG G+P ++H        E +   L     +         +GG +G G  + N  S    VI   DG   Q+KY +     
Subjt:  MDSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFSTEF-VIETADGKR-QKKYKQVFSDN

Query:  MGNKSEPTITKC------KEGDNWTKVTFKPDLAKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKR
           K   T+T C        G   T + F PD   F      + + +A   + +  L   +  ++K E +     V S   Y     +  S   T+  K 
Subjt:  MGNKSEPTITKC------KEGDNWTKVTFKPDLAKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKR

Query:  YHIKPNERWEIVVTLSEGQFQ---------QVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWV------------------
         H     R EI  +  +   Q          + + N I TI GGTH++ +   +    +N + KK K   VK + + S  W+                  
Subjt:  YHIKPNERWEIVVTLSEGQFQ---------QVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWV------------------

Query:  -------------------FINALIDNPAFDSQTKETL---TIR-------QSSFGSACELTPEFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGA-KT
                            ++  + NP F+ QTK  L    +R       Q       EL P+ L+++ +KS  + +  + +  K++++L ++    K+
Subjt:  -------------------FINALIDNPAFDSQTKETL---TIR-------QSSFGSACELTPEFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGA-KT

Query:  EKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGH
          + G  KL D +      SE   + + EGDSA   A  G     R F  + PLRGK+LN+       + +N+EIQ +   LGL    E  N + LRY  
Subjt:  EKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGH

Query:  LMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLG
        ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K   R       Y     +    S  GNAS ++I+ +KGLG
Subjt:  LMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLG

AT3G23890.1 topoisomerase II

0.0e+00

61.41

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Query:  KRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSM
        K PLQNSNAANV   PA   A AG  KTIEEMYQKK+QLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R VTYVPGLYKIFDEILVNAADNKQRD  M
Subjt:  KRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSM

Query:  DSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDNMGNKS
        DSV+VVIDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADGKR KKYKQVF +NMG KS
Subjt:  DSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDNMGNKS

Query:  EPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENP-KRYHIKPNERWEI
        EP ITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+   TE+P  R   K N+RWE+
Subjt:  EPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENP-KRYHIKPNERWEI

Query:  VVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLK
         V+LSEGQFQQVSFVN IATIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWVF+NALIDNPAFDSQTKETLT+RQSSFGS CEL+ +FLK
Subjt:  VVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLK

Query:  NVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ
         V  KSG++E++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGK+S  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ Q
Subjt:  NVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ

Query:  ITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWK
        IT NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WK
Subjt:  ITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWK

Query:  ESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSIAD
        ESL+GNA+GW IKYYKGLGTST++EG+EYF  LG HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ +  + YSDFVNKELILFS+AD
Subjt:  ESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSIAD

Query:  LQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNFRVTYLSTLL---------------IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTK
        LQRSIPS+VDGLKPGQRKIL V  +    K+ K     V Y+S L                +  D+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TK
Subjt:  LQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNFRVTYLSTLL---------------IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTK

Query:  LSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGGI
        LS VTR LFPKDDD LL+YLNEDGQ IEPTWYMP+IP VLVNG+EGIGTGWS++IPNYNPR+I+ANVRRLL+GE+M+PMDPWY+GF GTIEKTA++EGG 
Subjt:  LSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGGI

Query:  SYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVST
        +YT++G  EEV +TT+RITELP+RRW +DYK FL S+     K D         PF +    ++D+K V  D+ L+EENM+ A QEG  KKFKLTTT++T
Subjt:  SYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVST

Query:  SNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVA
        SNMHLFD  GVIKKY TPEQILEEFF LR E+YEKRK T+++N+E+ELLKLENK RFILAV++GEIIV+ R++ D+  +L+ KGFTPFP+K +SVE  +A
Subjt:  SNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVA

Query:  G-----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEV--RK
        G     A+ E EE    PE     +  S+Y+YLLA+AI +LTIEKV+EL  DRDK+   V D++K TPKSLWL DL+SLDKEL+++D  DAQ ++     
Subjt:  G-----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEV--RK

Query:  QQRSKANNDVKPKISRNAPKAP---RNNKKTSNSETVTESMDTTSSSTTMEVASNAVKPKGKAAPRK---------------------APAKKPQGKAGG
        Q++ +A +    K+ R APK P   +  KK S SET   S    S+  T    +  VKPK +   +K                     A   KP+G+ G 
Subjt:  QQRSKANNDVKPKISRNAPKAP---RNNKKTSNSETVTESMDTTSSSTTMEVASNAVKPKGKAAPRK---------------------APAKKPQGKAGG

Query:  LLNNDGDVD--EDDEVLELKDRLAAYKLESSPDRSEVSTMETEVPQVQAANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGG
                   E+DE+L+L  RLA Y   S+P                           A   KT+  S  I+ +DD DD    + E+AP   KKGG   
Subjt:  LLNNDGDVD--EDDEVLELKDRLAAYKLESSPDRSEVSTMETEVPQVQAANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGG

Query:  RKANAANAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEE--EAAAGNEGKLMMGSASSSETTEE
             A  K  KPPAA +KR        +++          G+SPEKKVRK+R+SPFNKKS SV+ R+ + +EEE  E  AGN             ++E+
Subjt:  RKANAANAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEE--EAAAGNEGKLMMGSASSSETTEE

Query:  VAGFLPARGRSQRANRTQVRYVVSDSDSEPVSVDSDFDEEEADFDED
          G + A  R QRANR ++ YV+SDS+SE  + DS+FD+ E D D++
Subjt:  VAGFLPARGRSQRANRTQVRYVVSDSDSEPVSVDSDFDEEEADFDED

AT3G23890.2 topoisomerase II

0.0e+00

62.3

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Query:  KRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSM
        K PLQNSNAANV   PA   A AG  KTIEEMYQKK+QLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R VTYVPGLYKIFDEILVNAADNKQRD  M
Subjt:  KRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSM

Query:  DSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDNMGNKS
        DSV+VVIDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADGKR KKYKQVF +NMG KS
Subjt:  DSVKVVIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDNMGNKS

Query:  EPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENP-KRYHIKPNERWEI
        EP ITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+   TE+P  R   K N+RWE+
Subjt:  EPTITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENP-KRYHIKPNERWEI

Query:  VVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLK
         V+LSEGQFQQVSFVN IATIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWVF+NALIDNPAFDSQTKETLT+RQSSFGS CEL+ +FLK
Subjt:  VVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLK

Query:  NVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ
         V  KSG++E++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGK+S  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ Q
Subjt:  NVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ

Query:  ITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWK
        IT NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WK
Subjt:  ITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWK

Query:  ESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSIAD
        ESL+GNA+GW IKYYKGLGTST++EG+EYF  LG HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ +  + YSDFVNKELILFS+AD
Subjt:  ESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSIAD

Query:  LQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNFRVTYLSTLL---------------IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTK
        LQRSIPS+VDGLKPGQRKIL V  +    K+ K     V Y+S L                +  D+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TK
Subjt:  LQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNFRVTYLSTLL---------------IIMDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTK

Query:  LSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGGI
        LS VTR LFPKDDD LL+YLNEDGQ IEPTWYMP+IP VLVNG+EGIGTGWS++IPNYNPR+I+ANVRRLL+GE+M+PMDPWY+GF GTIEKTA++EGG 
Subjt:  LSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKTATREGGI

Query:  SYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVST
        +YT++G  EEV +TT+RITELP+RRW +DYK FL S+     K D         PF +    ++D+K V  D+ L+EENM+ A QEG  KKFKLTTT++T
Subjt:  SYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVST

Query:  SNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVA
        SNMHLFD  GVIKKY TPEQILEEFF LR E+YEKRK T+++N+E+ELLKLENK RFILAV++GEIIV+ R++ D+  +L+ KGFTPFP+K +SVE  +A
Subjt:  SNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVA

Query:  G-----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEV--RK
        G     A+ E EE    PE     +  S+Y+YLLA+AI +LTIEKV+EL  DRDK+   V D++K TPKSLWL DL+SLDKEL+++D  DAQ ++     
Subjt:  G-----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEV--RK

Query:  QQRSKANNDVKPKISRNAPKAP---RNNKKTSNSETVTESMDTTSSSTTMEVASNAVKPKGK-AAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDR
        Q++ +A +    K+ R APK P   +  KK S SET   S    S+  T    +  VKPKG+  A +KAPA   +              E+DE+L+L  R
Subjt:  QQRSKANNDVKPKISRNAPKAP---RNNKKTSNSETVTESMDTTSSSTTMEVASNAVKPKGK-AAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDR

Query:  LAAYKLESSPDRSEVSTMETEVPQVQAANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREP
        LA Y   S+P                           A   KT+  S  I+ +DD DD    + E+AP   KKGG        A  K  KPPAA +KR  
Subjt:  LAAYKLESSPDRSEVSTMETEVPQVQAANKKEPSKRAAAKKKTSAKSAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREP

Query:  AAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEE--EAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYV
              +++          G+SPEKKVRK+R+SPFNKKS SV+ R+ + +EEE  E  AGN             ++E+  G + A  R QRANR ++ YV
Subjt:  AAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEE--EAAAGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYV

Query:  VSDSDSEPVSVDSDFDEEEADFDED
        +SDS+SE  + DS+FD+ E D D++
Subjt:  VSDSDSEPVSVDSDFDEEEADFDED

AT5G04130.1 DNA GYRASE B2

4.5e-28

24.72

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Query:  EMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQE
        E  Q    L+ +  RP  Y+GS                     T   GL+ +  EIL NA D  Q   +   V VV+  +   +SV +NG G+P ++H  
Subjt:  EMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVEIHQE

Query:  ERVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDNMGNKSEP-TITKCK------EGDNWTKVTFKPD
         +    E +   L     +  T      +GG +G G  + N  S    +E +  +   ++KQ +S     + +P T   C+      +G   T + F PD
Subjt:  ERVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDNMGNKSEP-TITKCK------EGDNWTKVTFKPD

Query:  LAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQ-----------DYVDLYLKSASPFPTENPKRYHIKPNERWEIVVTLSEGQFQ-
           F  T +E D   +   R+ +LA  L   V + L  +    +  Q           +YV       +P       R  I      ++ +      +  
Subjt:  LAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQ-----------DYVDLYLKSASPFPTENPKRYHIKPNERWEIVVTLSEGQFQ-

Query:  -QVSFVNGIATIKGGTHVDYITNQIANYVMNVVNK----KNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETL---TIR-------QSSFGSACELT
          + + N I TI GGTH++ +   +   +  +  K    K K+ ++   +V+  L   ++  + NP F+ QTK  L    +R       Q       EL 
Subjt:  -QVSFVNGIATIKGGTHVDYITNQIANYVMNVVNK----KNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETL---TIR-------QSSFGSACELT

Query:  PEFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVR
        P+ L+++ +KS  + +  + +  K++++L ++    K+  + G  KL D +    + SE   + + EGDSA   A  G     R F  + PLRGK+LN+ 
Subjt:  PEFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVR

Query:  EASSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEY
              + +N+EIQ +   LGL    E    + LRY  ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K   R       Y   + 
Subjt:  EASSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEY

Query:  ESWKESLRGNASGWSIKYYKGLG
        +    +   NAS ++I+ +KGLG
Subjt:  ESWKESLRGNASGWSIKYYKGLG

Sequences

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CDS sequence

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ATGGCTGTGGAGAAGAAACGCCCATTGCAGAACAGCAATGCCGCCAATGTTGACTCCTTTCCGGCGTCCGGTGAAGCAGGAGCAGGACCGACGAAAACAATTGAAGAAAT
GTATCAGAAGAAGACTCAGCTCGAGCACATCCTCCTCAGACCTGATACCTACGTTGGATCAATTGAAAAGCATACTCAAAACCTCTGGGTTTACGAGAACGACAAGATGG
TGCACCGATCCGTTACCTACGTCCCTGGCCTCTACAAGATCTTTGATGAAATCTTGGTCAATGCTGCAGACAACAAGCAGAGAGACCCCTCGATGGACTCGGTCAAGGTT
GTTATTGATGTCGAACAGAACTGTATCAGTGTGTTCAACAATGGAGATGGAGTTCCTGTTGAGATTCATCAGGAAGAGAGAGTTTATGTGCCTGAGTTGATCTTTGGCCA
TCTGTTGACCAGTAGTAATTATGACGATACGGAGAAGAAAACCACTGGTGGACGCAACGGCTACGGTGCCAAACTTACGAATATTTTCTCGACTGAATTTGTTATTGAGA
CGGCTGATGGAAAACGCCAGAAGAAGTATAAGCAGGTATTCTCTGACAACATGGGAAACAAATCCGAGCCTACCATAACAAAGTGCAAGGAGGGTGATAATTGGACCAAG
GTGACTTTTAAGCCAGACTTGGCAAAGTTTAATATGACTCATCTTGAAGATGATGTTGTCGCACTGATGAAAAAGCGGGTGTTGGATTTGGCCGGCTGCCTCGGAAAAAC
CGTGAAGGTTGAGCTGAATGGACAAAGGGTCCCTGTTAAATCATTTCAAGATTATGTAGATCTCTACCTCAAATCGGCATCCCCATTCCCGACAGAAAATCCAAAAAGGT
ATCACATAAAGCCTAATGAGAGATGGGAAATCGTGGTGACCTTAAGTGAGGGGCAGTTCCAGCAGGTCAGCTTTGTGAACGGAATTGCAACTATAAAGGGTGGGACTCAT
GTTGATTACATCACTAATCAGATCGCAAATTATGTGATGAATGTTGTAAATAAGAAGAATAAAAATGCTAACGTGAAGGCCCACAACGTGAAGAGTTACTTGTGGGTTTT
TATCAACGCTCTCATTGATAATCCTGCCTTCGACTCCCAAACCAAGGAGACTTTGACAATTCGTCAAAGCAGTTTCGGTTCTGCATGCGAACTTACGCCAGAGTTTTTGA
AGAATGTGGCCACGAAATCTGGAATTATGGAAAGCGTTCTCTCGTGGGTTAATTTCAAGCAAAGCAAAGACCTGAAGAAAACTGATGGAGCAAAAACAGAAAAAATTAGT
GGTATCGAAAAGTTGGAGGATGCCAATTGCGCTGGAGGGAAAAGCTCGGAAAAATGTACCTTGATTTTGACAGAAGGAGATTCAGCCAAGGCCCTTGCAATGGCTGGGCT
CGGTGTTGTGGGACGAGATTTCTATGGCGTATTCCCACTGAGAGGCAAATTGCTTAATGTGAGGGAAGCGAGTAGTAAACAGATCACAGAGAACAAAGAAATTCAGTACA
TTAAGCAGATTCTTGGACTTCAGCAAGGGAAGGAATACAACAATGCCAAGGCTTTGAGATATGGTCATTTGATGATAATGACCGATCAGGATCACGACGGTTCGCACATT
AAAGGACTCTTGATCAACTTTATTCATTCTTTCTGGCCTTCTCTCCTAAAAGTACCGTCTTTCTTGGTTGAGTTCATAACGCCTATTGTCAAGGCTACTCATAGGAATGG
AACTGTTTTATCATTCTATACCATGCCCGAGTACGAGTCTTGGAAAGAGAGCTTGAGGGGCAATGCAAGTGGCTGGTCTATCAAGTACTATAAGGGGTTGGGAACAAGCA
CATCGAAAGAAGGAAGAGAGTACTTTGAACAGCTGGGAAAGCACAAGAAAGATTTTATTTGGCAAGATGACCACGATGGGGAGGCCATTGAACTTGCATTCAGTAAGAAG
AAGATTGAAGAGAGGAAGAATTGGCTCCGTCATTTTGAGCCTGGTACCCATCTAGATCAGACCGAAAAATTGATAAAATACAGTGACTTCGTCAACAAGGAGCTTATATT
ATTTTCAATTGCTGATTTACAAAGGTCTATTCCCTCAGTGGTTGATGGTCTCAAGCCTGGCCAGAGAAAGATCCTTTCTGTTCTTTCAAGAGGAACTTTATCAAAGAAGC
AAAAATTTCTCAATTTTCGGGTTACGTATCTGAGCACTCTGCTTATCATCATGGACTTTGTCGGCAGCAACAACATTAATCTTCTTCTGCCAAATGGACAGTTTGGCACC
CGGAACCATGGAGGCAAAGATCATGCAAGTTCTAGGTACATTTACACTAAGCTTTCAAATGTTACACGGTTTCTCTTCCCAAAAGACGATGACAAGCTTCTTAACTACTT
AAATGAAGACGGCCAGTCGATTGAACCAACCTGGTACATGCCTGTCATACCAATGGTTCTTGTCAACGGAAGTGAAGGAATTGGAACTGGGTGGAGTTCGTACATTCCAA
ATTACAACCCCAGAGATATCATTGCAAATGTAAGACGCCTGTTGGATGGTGAAACGATGTTGCCAATGGATCCCTGGTATAAAGGTTTTGCAGGAACTATTGAGAAAACT
GCCACTAGGGAAGGAGGTATTAGTTACACTGTTAGTGGAACTATAGAGGAAGTCTGCGATACTACGTTGAGAATAACTGAACTGCCAGTCCGCCGGTGGACTAATGATTA
TAAGGAATTCCTTGATTCTGTCACTAGAGTTGCAGCAAAGAATGACAAAGACAAAGAAAAAGCAGCGAAGGATCCTTTTATTGAGCAAGCTGATCACCACAGCGATGACA
AAATTGTTTCCATTGATGTTCACTTGACGGAGGAAAACATGATGCTGGCCCTGCAGGAGGGTTTGAAGAAGAAATTCAAATTAACTACTACTGTCAGCACAAGTAACATG
CACCTGTTTGATGCAAACGGCGTGATTAAGAAATATGACACCCCAGAACAAATTCTTGAGGAATTTTTTCCCCTTAGACTTGAATTCTATGAAAAAAGAAAGAGAACTCT
TTTGGAAAACCTTGAAATGGAGTTGCTTAAACTTGAGAACAAGGTTAGGTTTATCCTTGCTGTTGTGAATGGAGAGATAATAGTGAGCAATAGAAGAAGAGTTGATTTAT
TCCATGAGCTTCAAGCGAAAGGCTTTACACCCTTTCCGAAGAAGACTAAATCTGTTGAGCCGGAGGTTGCTGGGGCATCTAATGAAACAGAAGAAACAGAGGAGAGCCCA
GAAGTAAAAGGGGAGCGGGTTAGTGACTACGAGTATCTACTGGCTCTGGCAATCGGAACCTTGACCATTGAGAAGGTTCAGGAGCTATGTAATGATAGAGACAAGCTCAA
AGGGGAAGTGGAAGATCTGAGGAAGGCAACCCCCAAGTCTCTGTGGCTGAAAGATCTTGATTCTCTTGACAAGGAACTTGATGAGATGGATAGAAATGATGCTCAGGCAG
AGGAGGTAAGAAAACAGCAGAGAAGCAAAGCAAATAACGATGTAAAGCCAAAGATCTCTAGGAATGCACCAAAAGCTCCACGCAACAATAAGAAAACCAGCAATTCAGAA
ACCGTCACGGAAAGTATGGACACAACATCTAGTTCTACAACAATGGAAGTTGCAAGTAACGCGGTGAAGCCCAAAGGCAAAGCAGCTCCAAGAAAAGCTCCCGCTAAAAA
GCCGCAGGGTAAAGCTGGAGGACTTCTCAACAATGATGGTGATGTCGACGAGGACGATGAAGTGCTCGAGCTTAAAGATCGTCTTGCCGCCTACAAACTGGAATCATCTC
CTGATCGATCAGAAGTTTCAACCATGGAAACTGAAGTGCCACAAGTCCAAGCGGCCAACAAGAAAGAACCCAGCAAGAGAGCAGCTGCCAAGAAAAAAACTTCTGCGAAG
TCTGCTCAGATTTCCGATAACGACGACAGCGACGATGAAGACTTTGAGATAAAGGAGATAGCTCCTCCCGCAGCCAAGAAGGGAGGCGGAGGAGGAAGAAAGGCTAATGC
TGCAAATGCCAAAACAACCAAACCCCCGGCGGCAGCGAAGAAGCGAGAACCGGCGGCGAAGTTGGGGCAGAAACTTATAACTCAAATGTTGGAGCCGGCAGAGAACTCCG
GCATCTCGCCGGAGAAGAAAGTGAGGAAGATAAGAGCATCTCCTTTCAACAAAAAAAGTGGCTCTGTCTTGGGAAGGGTTGGGGAAGAGGAAGAGGAAGAAGAAGCTGCT
GCTGGAAATGAAGGGAAGCTGATGATGGGTTCTGCTTCTTCTTCTGAGACGACTGAAGAAGTCGCCGGATTTCTGCCGGCGAGAGGAAGGTCCCAGAGGGCAAACAGAAC
CCAGGTCAGATATGTAGTTAGTGACTCAGACAGTGAGCCAGTTTCTGTAGATTCAGACTTCGATGAAGAAGAAGCTGACTTTGATGAAGATTGA

mRNA sequence

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Protein sequence

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MAVEKKRPLQNSNAANVDSFPASGEAGAGPTKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKV
VIDVEQNCISVFNNGDGVPVEIHQEERVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSDNMGNKSEPTITKCKEGDNWTK
VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASPFPTENPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTH
VDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNVATKSGIMESVLSWVNFKQSKDLKKTDGAKTEKIS
GIEKLEDANCAGGKSSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHI
KGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLGKHKKDFIWQDDHDGEAIELAFSKK
KIEERKNWLRHFEPGTHLDQTEKLIKYSDFVNKELILFSIADLQRSIPSVVDGLKPGQRKILSVLSRGTLSKKQKFLNFRVTYLSTLLIIMDFVGSNNINLLLPNGQFGT
RNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPVIPMVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLDGETMLPMDPWYKGFAGTIEKT
ATREGGISYTVSGTIEEVCDTTLRITELPVRRWTNDYKEFLDSVTRVAAKNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMMLALQEGLKKKFKLTTTVSTSNM
HLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRTLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESP
EVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLDKELDEMDRNDAQAEEVRKQQRSKANNDVKPKISRNAPKAPRNNKKTSNSE
TVTESMDTTSSSTTMEVASNAVKPKGKAAPRKAPAKKPQGKAGGLLNNDGDVDEDDEVLELKDRLAAYKLESSPDRSEVSTMETEVPQVQAANKKEPSKRAAAKKKTSAK
SAQISDNDDSDDEDFEIKEIAPPAAKKGGGGGRKANAANAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSVLGRVGEEEEEEEAA
AGNEGKLMMGSASSSETTEEVAGFLPARGRSQRANRTQVRYVVSDSDSEPVSVDSDFDEEEADFDED

Sgr030373 (gene) of Monk fruit (Qingpiguo) v1 genome