CuGenDBv2

Gene ID	Sgr030429
Organism	Siraitia grosvenorii cv. Qingpiguo (Monk fruit (Qingpiguo) v1)
Description	phosphatidyl-N-methylethanolamine N-methyltransferase
Genome location	tig00153640:3508418..3511318
RNA-Seq Expression	Sgr030429
Synteny	Sgr030429
Gene Ontology terms	GO:0006656 - phosphatidylcholine biosynthetic process (biological process) GO:0032259 - methylation (biological process) GO:0005789 - endoplasmic reticulum membrane (cellular component) GO:0016021 - integral component of membrane (cellular component) GO:0000773 - phosphatidyl-N-methylethanolamine N-methyltransferase activity (molecular function) GO:0004608 - phosphatidylethanolamine N-methyltransferase activity (molecular function) GO:0080101 - phosphatidyl-N-dimethylethanolamine N-methyltransferase activity (molecular function)
InterPro domains	IPR007318 - Phospholipid methyltransferase IPR024960 - Phosphatidyl-N-methylethanolamine/Phosphatidylethanolamine N-methyltransferase

Homology

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GenBank top hits

e value

%identity

Alignment

KAG7036543.1 Phosphatidyl-N-methylethanolamine N-methyltransferase [Cucurbita argyrosperma subsp. argyrosperma]

1.8e-81

88.41

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Query:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE
        M ++AV+GVLLPFP+YYVLWTRPQLWVNLC KW EP KLMAQVS+FLK+LQFLS+LHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGE+GVYYGVRFG+
Subjt:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE

Query:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS
        NIPWV EFPFGYIKDPQYVGSILSL ACLSWVPLQYILLWT+GYVFMM VESKED  TRAKPQS
Subjt:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS

XP_004137657.1 phosphatidyl-N-methylethanolamine N-methyltransferase [Cucumis sativus]

6.6e-84

90.85

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Query:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE
        MGI AV+GVLLPFP+YYVLW RPQLWVNLC K REPCKLMAQVS+FLK+LQFLS++HVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFG+
Subjt:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE

Query:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS
        NIPWV EFPFGYIKDPQYVGSILSLFACLSWVPL+YILLWTLGY+FMMHVESKED ATRAKPQS
Subjt:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS

XP_008465151.2 PREDICTED: phosphatidyl-N-methylethanolamine N-methyltransferase [Cucumis melo]

2.7e-85

91.46

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Query:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE
        MGI+AV+GVLLPFP+YYVLW RPQLWVNLC K REPCKLMAQVS+FLK+LQFLS++HVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFG+
Subjt:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE

Query:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS
        NIPWV EFPFGYIKDPQYVGSILSLFACLSWVPL+YILLWTLGY+FMMHVESKEDPATRAKPQS
Subjt:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS

XP_022153398.1 phosphatidyl-N-methylethanolamine N-methyltransferase [Momordica charantia]

5.6e-83

90.24

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Query:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE
        MGI+A +GVLLPFPFYYVLWTRPQLW N C KWREPCKLMA+VSIFLK+LQFLS+LHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFG+
Subjt:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE

Query:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS
        NIPWV EFPFGYI+DPQYVGSILS+FACLSWVPLQYILL TLGYVFMM VESKEDP TRAKPQS
Subjt:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS

XP_038903463.1 phosphatidyl-N-methylethanolamine N-methyltransferase [Benincasa hispida]

1.5e-83

88.41

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Query:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE
        MGI+AV+GVLLPFP+YYVLW+RPQLWVNLC K R+PCKLMAQVS+FLK+LQFLS+ HVSSF+WPPPLYFWPLMAFGQFLNFRVYQLLGE+GVYYGVRFG+
Subjt:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE

Query:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS
        NIPWV EFPFGYIKDPQYVGSILSLFACLSWVPLQYI+LWTLGY+FMMH+ESKE PATRAKPQS
Subjt:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS

TrEMBL top hits

e value

%identity

Alignment

A0A1S3CPQ5 phosphatidyl-N-methylethanolamine N-methyltransferase

1.3e-85

91.46

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Query:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE
        MGI+AV+GVLLPFP+YYVLW RPQLWVNLC K REPCKLMAQVS+FLK+LQFLS++HVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFG+
Subjt:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE

Query:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS
        NIPWV EFPFGYIKDPQYVGSILSLFACLSWVPL+YILLWTLGY+FMMHVESKEDPATRAKPQS
Subjt:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS

A0A2P6RVH2 Phosphatidyl-N-methylethanolamine N-methyltransferase

2.5e-73

80.49

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Query:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE
        MGI A +GVL PFPFYY LWT PQ WV LC   R+PCK+MA V+ FLK++QFLSL+ VS+ SWPPPLYFWPL+AFGQFLNFRVYQLLGE+G YYGVRFG+
Subjt:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE

Query:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS
        NIPWV EFPFGYIKDPQYVGSILSLFACLSWVP  YI LWTLGYVFM+HVESKEDPATRAKP S
Subjt:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS

A0A6J1DHC8 phosphatidyl-N-methylethanolamine N-methyltransferase

2.7e-83

90.24

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Query:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE
        MGI+A +GVLLPFPFYYVLWTRPQLW N C KWREPCKLMA+VSIFLK+LQFLS+LHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFG+
Subjt:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE

Query:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS
        NIPWV EFPFGYI+DPQYVGSILS+FACLSWVPLQYILL TLGYVFMM VESKEDP TRAKPQS
Subjt:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS

A0A6J1GCG7 phosphatidyl-N-methylethanolamine N-methyltransferase

4.3e-81

87.8

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Query:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE
        M ++AV+GVLLPFP+YYVLWTRPQLWVNLC KW EP KLMAQVS+FLK+LQ LS+LHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGE+GVYYGVRFG+
Subjt:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE

Query:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS
        NIPWV EFPFGYIKDPQYVGSILSL ACLSWVPLQYILLWT+GYVFMM VESKED  TRAKPQS
Subjt:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS

A0A6J1KB80 phosphatidyl-N-methylethanolamine N-methyltransferase

1.9e-81

87.8

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Query:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE
        M ++AV+GVLLPFP+YY+LWTRPQLWVNLC KW EP KLMAQVS+FLK+LQFLS+LHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGE+GVYYGVRFG+
Subjt:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE

Query:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS
        NIPWV EFPFGYIKDPQYVGSILSL ACLSWVPLQYILLWT+GYVFMM VESKED  TRAKPQS
Subjt:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS

SwissProt top hits

e value

%identity

Alignment

Q9SAH5 Phosphatidyl-N-methylethanolamine N-methyltransferase

1.8e-68

75.16

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Query:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE
        MG++A +GVLLPFPFY+ LWT  Q WVNLC + R+P  +MA+VS  LK  Q LSL  V+S SWPPPLYFWPLMAFGQFLNFRVYQLLGE+G YYGVRFG+
Subjt:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE

Query:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAK
        NIPWV EFPFG I+DPQYVGSI+SL ACLSWVP QYILLW+LGYVFMM +ESKEDP  RAK
Subjt:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAK

Arabidopsis top hits

e value

%identity

Alignment

AT1G80860.1 phospholipid N-methyltransferase

1.3e-69

75.16

Show/hide

Query:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE
        MG++A +GVLLPFPFY+ LWT  Q WVNLC + R+P  +MA+VS  LK  Q LSL  V+S SWPPPLYFWPLMAFGQFLNFRVYQLLGE+G YYGVRFG+
Subjt:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE

Query:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAK
        NIPWV EFPFG I+DPQYVGSI+SL ACLSWVP QYILLW+LGYVFMM +ESKEDP  RAK
Subjt:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAK

AT1G80860.2 phospholipid N-methyltransferase

1.3e-69

75.16

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Query:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE
        MG++A +GVLLPFPFY+ LWT  Q WVNLC + R+P  +MA+VS  LK  Q LSL  V+S SWPPPLYFWPLMAFGQFLNFRVYQLLGE+G YYGVRFG+
Subjt:  MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGE

Query:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAK
        NIPWV EFPFG I+DPQYVGSI+SL ACLSWVP QYILLW+LGYVFMM +ESKEDP  RAK
Subjt:  NIPWVAEFPFGYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAK

Sequences

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CDS sequence

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ATGGGCATAATGGCAGTAATGGGAGTGCTGCTGCCATTTCCGTTCTACTACGTGTTATGGACTCGTCCACAGTTATGGGTTAACTTGTGCGCGAAATGGCGCGAACCCTG
CAAATTGATGGCTCAAGTCTCGATTTTCCTCAAGATGCTTCAGTTCCTCTCCCTCCTCCACGTCTCCTCTTTCTCCTGGCCGCCGCCTCTCTACTTCTGGCCCCTTATGG
CCTTTGGCCAATTTTTGAACTTCAGGGTCTACCAGTTACTCGGAGAATCTGGTGTTTACTATGGAGTACGGTTTGGAGAGAACATTCCATGGGTGGCAGAATTTCCATTT
GGATATATAAAAGATCCTCAGTATGTGGGAAGCATTTTGAGCCTTTTTGCTTGTCTTTCTTGGGTACCCTTACAATATATACTGCTGTGGACGCTGGGATACGTCTTTAT
GATGCACGTTGAATCCAAGGAAGATCCTGCAACTCGTGCAAAGCCTCAAAGTTAA

mRNA sequence

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Protein sequence

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MGIMAVMGVLLPFPFYYVLWTRPQLWVNLCAKWREPCKLMAQVSIFLKMLQFLSLLHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGENIPWVAEFPF
GYIKDPQYVGSILSLFACLSWVPLQYILLWTLGYVFMMHVESKEDPATRAKPQS

Sgr030429 (gene) of Monk fruit (Qingpiguo) v1 genome