CuGenDBv2

Gene ID	Spg010554
Organism	Luffa cylindrica (Sponge gourd (cylindrica) v1)
Description	insulin-degrading enzyme-like 1, peroxisomal
Genome location	scaffold5:9507858..9519967
RNA-Seq Expression	Spg010554
Synteny	Spg010554
Gene Ontology terms	GO:0006508 - proteolysis (biological process) GO:0004222 - metalloendopeptidase activity (molecular function) GO:0046872 - metal ion binding (molecular function)
InterPro domains	IPR007863 - Peptidase M16, C-terminal IPR011249 - Metalloenzyme, LuxS/M16 peptidase-like IPR026960 - Reverse transcriptase zinc-binding domain

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAG6580840.1 Insulin-degrading enzyme-like 1, peroxisomal, partial [Cucurbita argyrosperma subsp. sororia]

7.4e-118

85.71

Show/hide

Query:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE
        +MS D   R+ +    EN+K +L        LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFY+NNYSSN+MHLVVYAKENLDKVQ LVE
Subjt:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE

Query:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
        NIFQDIPNNNCNRANFPGQPC SEHLQVLVRA+PIKQGHKLRI WPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
Subjt:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF

Query:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL
        FKV IDLTDVGQEHMQDVVGLLFKYISLLK+SGIC+WIFDE+S++
Subjt:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL

KAG7017597.1 Insulin-degrading enzyme-like 1, peroxisomal, partial [Cucurbita argyrosperma subsp. argyrosperma]

7.4e-118

85.71

Show/hide

Query:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE
        +MS D   R+ +    EN+K +L        LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFY+NNYSSN+MHLVVYAKENLDKVQ LVE
Subjt:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE

Query:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
        NIFQDIPNNNCNRANFPGQPC SEHLQVLVRA+PIKQGHKLRI WPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
Subjt:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF

Query:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL
        FKV IDLTDVGQEHMQDVVGLLFKYISLLK+SGIC+WIFDE+S++
Subjt:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL

XP_022934728.1 insulin-degrading enzyme-like 1, peroxisomal [Cucurbita moschata]

7.4e-118

85.71

Show/hide

Query:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE
        +MS D   R+ +    EN+K +L        LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFY+NNYSSN+MHLVVYAKENLDKVQ LVE
Subjt:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE

Query:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
        NIFQDIPNNNCNRANFPGQPC SEHLQVLVRA+PIKQGHKLRI WPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
Subjt:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF

Query:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL
        FKV IDLTDVGQEHMQDVVGLLFKYISLLK+SGIC+WIFDE+S++
Subjt:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL

XP_022982829.1 insulin-degrading enzyme-like 1, peroxisomal [Cucurbita maxima]

1.5e-118

86.12

Show/hide

Query:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE
        +MS D   R+ +    EN+K +L        LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSN+MHLVVYAKENLDKVQILVE
Subjt:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE

Query:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
        NIFQDIPNNNCNRANFPGQPC SEHLQVLVRA+PIKQGHKLRI WPI+PEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
Subjt:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF

Query:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL
        FKV IDLTDVGQEHMQDVVGLLFKYISLLK+SGIC+WIFDE+S++
Subjt:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL

XP_023526970.1 insulin-degrading enzyme-like 1, peroxisomal [Cucurbita pepo subsp. pepo]

7.4e-118

85.71

Show/hide

Query:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE
        +MS D   R+ +    EN+K +L        LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFY+NNYSSN+MHLVVYAKENLDKVQ LVE
Subjt:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE

Query:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
        NIFQDIPNNNCNRANFPGQPC SEHLQVLVRA+PIKQGHKLRI WPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
Subjt:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF

Query:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL
        FKV IDLTDVGQEHMQDVVGLLFKYISLLK+SGIC+WIFDE+S++
Subjt:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL

TrEMBL top hits

e value

%identity

Alignment

A0A1S3B7B5 insulin-degrading enzyme-like 1, peroxisomal isoform X1

2.3e-117

84.49

Show/hide

Query:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE
        +MS D   R+ +    EN+K +L        LQ HISSESHPFHKFSTGNW+TLEVQPKAKGLDTRHELLKFYENNYSSN+MHLVVYAKE LDKVQILVE
Subjt:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE

Query:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
        NIFQDIPN+NCNRANFPGQPCTSEHLQVLVRA+PIK+GHKLRI WPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
Subjt:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF

Query:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL
        FKVVIDLTDVGQEHMQ+V+GLLF+YISLLKQSGIC+WIFDE+S++
Subjt:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL

A0A1S3B826 insulin-degrading enzyme-like 1, peroxisomal isoform X2

2.3e-117

84.49

Show/hide

Query:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE
        +MS D   R+ +    EN+K +L        LQ HISSESHPFHKFSTGNW+TLEVQPKAKGLDTRHELLKFYENNYSSN+MHLVVYAKE LDKVQILVE
Subjt:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE

Query:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
        NIFQDIPN+NCNRANFPGQPCTSEHLQVLVRA+PIK+GHKLRI WPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
Subjt:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF

Query:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL
        FKVVIDLTDVGQEHMQ+V+GLLF+YISLLKQSGIC+WIFDE+S++
Subjt:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL

A0A5A7TLF9 Insulin-degrading enzyme-like 1, peroxisomal isoform X1

2.3e-117

84.49

Show/hide

Query:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE
        +MS D   R+ +    EN+K +L        LQ HISSESHPFHKFSTGNW+TLEVQPKAKGLDTRHELLKFYENNYSSN+MHLVVYAKE LDKVQILVE
Subjt:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE

Query:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
        NIFQDIPN+NCNRANFPGQPCTSEHLQVLVRA+PIK+GHKLRI WPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
Subjt:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF

Query:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL
        FKVVIDLTDVGQEHMQ+V+GLLF+YISLLKQSGIC+WIFDE+S++
Subjt:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL

A0A6J1F8G9 insulin-degrading enzyme-like 1, peroxisomal

3.6e-118

85.71

Show/hide

Query:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE
        +MS D   R+ +    EN+K +L        LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFY+NNYSSN+MHLVVYAKENLDKVQ LVE
Subjt:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE

Query:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
        NIFQDIPNNNCNRANFPGQPC SEHLQVLVRA+PIKQGHKLRI WPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
Subjt:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF

Query:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL
        FKV IDLTDVGQEHMQDVVGLLFKYISLLK+SGIC+WIFDE+S++
Subjt:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL

A0A6J1J5M2 insulin-degrading enzyme-like 1, peroxisomal

7.2e-119

86.12

Show/hide

Query:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE
        +MS D   R+ +    EN+K +L        LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSN+MHLVVYAKENLDKVQILVE
Subjt:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE

Query:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
        NIFQDIPNNNCNRANFPGQPC SEHLQVLVRA+PIKQGHKLRI WPI+PEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
Subjt:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF

Query:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL
        FKV IDLTDVGQEHMQDVVGLLFKYISLLK+SGIC+WIFDE+S++
Subjt:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL

SwissProt top hits

e value

%identity

Alignment

F4J3D9 Insulin-degrading enzyme-like 2

1.7e-85

66.82

Show/hide

Query:  LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVENIFQDIPNNNCNRANFPGQPCTSEHLQVLVR
        LQ+H+S E HP+HKFSTGN DTL V+P+  G+DTR EL+KFY+ +YS+NIMHLVVY KENLDK Q LVE +FQ I N N     FPGQPCT +HLQVLV+
Subjt:  LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVENIFQDIPNNNCNRANFPGQPCTSEHLQVLVR

Query:  AVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQ
        AVPI QGH+L ++WP+TP I HY+E PCRYLG LIGHEGEGSL++ LK LGWATGL AGE+D +M +SFF V IDLTD G EHMQD++GLLF+YI +L+Q
Subjt:  AVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQ

Query:  SGICEWIFDEVSSL
        SG+ +WIFDE+S++
Subjt:  SGICEWIFDEVSSL

O22941 Insulin-degrading enzyme-like 1, peroxisomal

1.6e-91

63.27

Show/hide

Query:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE
        +MS D   R+ +    EN+K +L        LQ+H+S E HP+HKFSTGN DTL V+P+AKG+DTR EL+KFYE +YS+NIMHLVVY KE+LDK+Q LVE
Subjt:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE

Query:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
         +FQ+I N N     FPGQPCT++HLQ+LV+A+PIKQGHKL ++WP+TP IHHY E P +YLGHLIGHEGEGSL++ LKTLGWATGLSAGE + T+++SF
Subjt:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF

Query:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL
        FKV IDLTD G EHMQ+++GLLF YI LL+Q+G+C+WIFDE+S++
Subjt:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL

P35559 Insulin-degrading enzyme

2.1e-46

Show/hide

Query:  NLDLDDHHSHVDDDLTEIIQL---PTLGFRLPSSRVMSLDGDDRKS-REENRKGILLQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYEN
        N   D  H H++  L    Q    P          V ++D +  K+   +  +   L++   +  HPF KF TGN  TLE +P  +G+D R ELLKF+  
Subjt:  NLDLDDHHSHVDDDLTEIIQL---PTLGFRLPSSRVMSLDGDDRKS-REENRKGILLQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYEN

Query:  NYSSNIMHLVVYAKENLDKVQILVENIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLY
         YSSN+M + V  +E+LD +  LV  +F ++ N N     FP  P   EHL+ L + VPIK    L + +PI     +YK  P  YLGHLIGHEG GSL 
Subjt:  NYSSNIMHLVVYAKENLDKVQILVENIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLY

Query:  YVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSLLTV
          LK+ GW   L  G+ +    F FF + +DLT+ G  H++D++  +F+YI  L+  G  EW+F E   L  V
Subjt:  YVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSLLTV

Q24K02 Insulin-degrading enzyme

3.5e-46

Show/hide

Query:  NLDLDDHHSHVDDDLTEIIQL---PTLGFRLPSSRVMSLDGDDRKS-REENRKGILLQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYEN
        N   D  H H++  L    Q    P          V ++D +  K+   +  +   L++   +  HPF KF TGN  TLE +P  +G+D R ELLKF+  
Subjt:  NLDLDDHHSHVDDDLTEIIQL---PTLGFRLPSSRVMSLDGDDRKS-REENRKGILLQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYEN

Query:  NYSSNIMHLVVYAKENLDKVQILVENIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLY
         YSSN+M + V  +E+LD +  LV  +F ++ N N     FP  P   EHL+ L + VPIK    L + +PI     +YK  P  YLGHLIGHEG GSL 
Subjt:  NYSSNIMHLVVYAKENLDKVQILVENIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLY

Query:  YVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSLLTV
          LK+ GW   L  G+ +    F FF + +DLT+ G  H++D++  +F+YI  L+  G  EW+F E   L  V
Subjt:  YVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSLLTV

Q9JHR7 Insulin-degrading enzyme

1.2e-46

37.36

Show/hide

Query:  NLDLDDHHSHVDDDLTEIIQL---PTLGFRLPSSRVMSLDGDDRKS-REENRKGILLQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYEN
        N   D  H H++  L    Q    P L        V ++D +  K+   +  +   L++   +  HPF KF TGN  TLE +P  +G+D R ELLKF+  
Subjt:  NLDLDDHHSHVDDDLTEIIQL---PTLGFRLPSSRVMSLDGDDRKS-REENRKGILLQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYEN

Query:  NYSSNIMHLVVYAKENLDKVQILVENIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLY
         YSSN+M + V  +E+LD +  LV  +F ++ N N     FP  P   EHL+ L + VPIK    L + +PI     +YK  P  YLGHLIGHEG GSL 
Subjt:  NYSSNIMHLVVYAKENLDKVQILVENIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLY

Query:  YVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSLLTV
          LK+ GW   L  G+ +    F FF + +DLT+ G  H++D++  +F+YI  L+  G  EW+F E   L  V
Subjt:  YVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSLLTV

Arabidopsis top hits

e value

%identity

Alignment

AT1G06900.1 Insulinase (Peptidase family M16) family protein

3.3e-31

35.78

Show/hide

Query:  LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVENIFQDIPNNNCNRANFPGQPCTSEHLQVLVR
        LQ + S++ HPF++F+ GN  +L       G+D R  ++K Y+  Y   +M LVV   E+LD ++  V  +F D+ N +  R     +    +  + L R
Subjt:  LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVENIFQDIPNNNCNRANFPGQPCTSEHLQVLVR

Query:  AVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFS----FFKVVIDLTDVGQEHMQDVVGLLFKYIS
           +K  H L + W + P    Y + P  YL HL+GHEG GSL+  LK  GWAT LSAG  D  +N S     F + I LTD G E + D++G +++Y+ 
Subjt:  AVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFS----FFKVVIDLTDVGQEHMQDVVGLLFKYIS

Query:  LLKQSGICEWIFDEVSSL
        LL+     EWIF E+  +
Subjt:  LLKQSGICEWIFDEVSSL

AT2G41790.1 Insulinase (Peptidase family M16) family protein

1.1e-92

63.27

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Query:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE
        +MS D   R+ +    EN+K +L        LQ+H+S E HP+HKFSTGN DTL V+P+AKG+DTR EL+KFYE +YS+NIMHLVVY KE+LDK+Q LVE
Subjt:  VMSLDGDDRKSR---EENRKGIL--------LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVE

Query:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF
         +FQ+I N N     FPGQPCT++HLQ+LV+A+PIKQGHKL ++WP+TP IHHY E P +YLGHLIGHEGEGSL++ LKTLGWATGLSAGE + T+++SF
Subjt:  NIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSF

Query:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL
        FKV IDLTD G EHMQ+++GLLF YI LL+Q+G+C+WIFDE+S++
Subjt:  FKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSL

AT3G57470.1 Insulinase (Peptidase family M16) family protein

1.2e-86

66.82

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Query:  LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVENIFQDIPNNNCNRANFPGQPCTSEHLQVLVR
        LQ+H+S E HP+HKFSTGN DTL V+P+  G+DTR EL+KFY+ +YS+NIMHLVVY KENLDK Q LVE +FQ I N N     FPGQPCT +HLQVLV+
Subjt:  LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVENIFQDIPNNNCNRANFPGQPCTSEHLQVLVR

Query:  AVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQ
        AVPI QGH+L ++WP+TP I HY+E PCRYLG LIGHEGEGSL++ LK LGWATGL AGE+D +M +SFF V IDLTD G EHMQD++GLLF+YI +L+Q
Subjt:  AVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQ

Query:  SGICEWIFDEVSSL
        SG+ +WIFDE+S++
Subjt:  SGICEWIFDEVSSL

AT3G57470.2 Insulinase (Peptidase family M16) family protein

1.2e-86

66.82

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Query:  LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVENIFQDIPNNNCNRANFPGQPCTSEHLQVLVR
        LQ+H+S E HP+HKFSTGN DTL V+P+  G+DTR EL+KFY+ +YS+NIMHLVVY KENLDK Q LVE +FQ I N N     FPGQPCT +HLQVLV+
Subjt:  LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVENIFQDIPNNNCNRANFPGQPCTSEHLQVLVR

Query:  AVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQ
        AVPI QGH+L ++WP+TP I HY+E PCRYLG LIGHEGEGSL++ LK LGWATGL AGE+D +M +SFF V IDLTD G EHMQD++GLLF+YI +L+Q
Subjt:  AVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQ

Query:  SGICEWIFDEVSSL
        SG+ +WIFDE+S++
Subjt:  SGICEWIFDEVSSL

AT3G57470.3 Insulinase (Peptidase family M16) family protein

1.2e-86

66.82

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Query:  LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVENIFQDIPNNNCNRANFPGQPCTSEHLQVLVR
        LQ+H+S E HP+HKFSTGN DTL V+P+  G+DTR EL+KFY+ +YS+NIMHLVVY KENLDK Q LVE +FQ I N N     FPGQPCT +HLQVLV+
Subjt:  LQRHISSESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVENIFQDIPNNNCNRANFPGQPCTSEHLQVLVR

Query:  AVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQ
        AVPI QGH+L ++WP+TP I HY+E PCRYLG LIGHEGEGSL++ LK LGWATGL AGE+D +M +SFF V IDLTD G EHMQD++GLLF+YI +L+Q
Subjt:  AVPIKQGHKLRIAWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQ

Query:  SGICEWIFDEVSSL
        SG+ +WIFDE+S++
Subjt:  SGICEWIFDEVSSL

Sequences

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CDS sequence

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ATGGCCGCCCGTGCCCACGACGTCGCCACCTTCAGCATCAAAGGCTCCTCCGCCACCCTCAATTTCCCCGACCTCCTCCACCTCCTCCCCCGCCCCGTCTCCCTCGCCCC
TCGCGACGTCCAAGCCGCCGCCGCCAAGGCCGCCCACATGCACAACCTCGACCTCGACGACCACCACTCCCACGTCGACGACGACCTCACCGAGATCATCCAACTCCCCA
CCCTCGGCTTCCGATTGCCTTCTTCTCGTGTAATGTCGCTGGATGGAGATGACCGGAAAAGTAGAGAAGAAAATAGAAAGGGCATTTTACTTCAGAGACATATAAGTTCT
GAAAGTCATCCATTTCATAAATTCAGCACAGGGAATTGGGACACTTTGGAGGTTCAACCAAAAGCTAAAGGGCTGGATACAAGACATGAACTTCTAAAATTCTATGAAAA
TAATTATTCATCCAATATCATGCATCTGGTTGTATATGCAAAAGAAAACCTTGATAAAGTACAAATCCTTGTGGAAAACATATTTCAAGATATTCCAAATAATAACTGCA
ACCGCGCTAATTTTCCTGGTCAGCCATGCACGTCAGAACATCTTCAGGTTCTTGTCAGAGCTGTTCCAATTAAACAAGGTCATAAATTGAGAATTGCTTGGCCAATAACT
CCTGAAATTCATCATTACAAGGAAGGGCCATGCCGGTATCTTGGTCATCTTATTGGTCATGAAGGAGAAGGATCCTTGTATTACGTTCTTAAAACATTAGGGTGGGCAAC
AGGGCTCTCAGCCGGTGAATCTGATTCCACCATGAACTTTTCCTTTTTCAAAGTAGTAATAGATCTCACTGATGTTGGTCAAGAACACATGCAAGATGTTGTTGGGCTAC
TCTTTAAATACATTAGCCTTTTGAAGCAATCTGGTATATGTGAATGGATATTTGATGAGGTTTCATCATTACTGACTGTTGGAGCAGGTGAAGATTATATGGATAGTGGC
GTCTTGTATAAATCCAATAGAGATTTTGTAGATACAGGAATCAGCAAGCCAATTTCCCCTAACATCTCTAGAAATCTCCACCCACGGCTAAAGAATCGTTTTGATTCTCT
TGCACACTTCAAATTGGGTAATGGAAGGAAAATCAGATTTTGGGAAGATCCTTGGCTGAATGGTTTGGCATTAAAGTTCAGTTTTCCTCGATTGTATGCTATTTCATCTT
CTCCACATGATTCTATTTCATTTCATTGGGATTTCCAAATTGGTGCTTGGAATCTTTCTTTTAGAAGATTATTAAAAGATGAGGAGATTGAAGACTTTCAAACTTTATTA
CTTAATATTTCACATGTGTCTCTTGGCTCAAATGACGATTCTAGACGGTGGTCAATTGATTCTTCAGGTATTTTTTCGGTTAAATCTTTAACTGATTATTTGTTGTCTTC
TCCATCATTGGAAAAAGAATTATATTCAGCATTGTGGAAGTCCAAGAGCCCCAAGAGAATCAACATTCTTTTGTGGATTATGTTAAATGGGAACCTCAATTCTTCAGAAG
TTCTTCAAAAGAAGATGCCAACTCTTTGCATATTGCCGTCAGTTTGTGTTCTATGTTTTCGAGATGAGGATTCTCTCAACCATATCTTCTTTAGCTGTTCCTATGCTAAA
TCGGGTTGGTTCAAGTTGTTTTCGATATTCAATCAGCATTGGGTTTTTTCTAATAACTTCCGTTGCAACATTTGTCAACTCTTATATGGATCAGCTCTTCTAAATCCTAA
AGCTAAGTTGCTTTGGATTAATGCGGTCAAAGCTTTTCTTTCGGAATTATGGTTGGAGCGAAATCAAAGAATTTTTCAGAGCAAGCATCTTCCTTGGATTGATCGTTTTG
AAGCTTCTCGTTTAAAGGCATCATCGTGGTGTTCTTTGTCCAAATTGTTTTTGGGATTCTCTCTACAGGACATATGTCTGAATTGGAATGCGTTTATATATCCTTCATAA

mRNA sequence

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Protein sequence

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MAARAHDVATFSIKGSSATLNFPDLLHLLPRPVSLAPRDVQAAAAKAAHMHNLDLDDHHSHVDDDLTEIIQLPTLGFRLPSSRVMSLDGDDRKSREENRKGILLQRHISS
ESHPFHKFSTGNWDTLEVQPKAKGLDTRHELLKFYENNYSSNIMHLVVYAKENLDKVQILVENIFQDIPNNNCNRANFPGQPCTSEHLQVLVRAVPIKQGHKLRIAWPIT
PEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDEVSSLLTVGAGEDYMDSG
VLYKSNRDFVDTGISKPISPNISRNLHPRLKNRFDSLAHFKLGNGRKIRFWEDPWLNGLALKFSFPRLYAISSSPHDSISFHWDFQIGAWNLSFRRLLKDEEIEDFQTLL
LNISHVSLGSNDDSRRWSIDSSGIFSVKSLTDYLLSSPSLEKELYSALWKSKSPKRINILLWIMLNGNLNSSEVLQKKMPTLCILPSVCVLCFRDEDSLNHIFFSCSYAK
SGWFKLFSIFNQHWVFSNNFRCNICQLLYGSALLNPKAKLLWINAVKAFLSELWLERNQRIFQSKHLPWIDRFEASRLKASSWCSLSKLFLGFSLQDICLNWNAFIYPS

Spg010554 (gene) of Sponge gourd (cylindrica) v1 genome