| GenBank top hits | e value | %identity | Alignment |
|---|
| XP_008455774.1 PREDICTED: L-2-hydroxyglutarate dehydrogenase, mitochondrial [Cucumis melo] | 4.3e-212 | 89.26 | Show/hide |
Query: MLKLAVQSLRGRSD-MVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDL
ML VQ+LRGR+ M +KISSM GTAKEKVDC+VIGAG+VGIAVARELSLRG+DVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDL
Subjt: MLKLAVQSLRGRSD-MVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDL
Query: LYQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAV
LY+YCSE +IPHKQIGKLIVATRTSEVPKLNELL RGVQNGVEGL+MVD ++AMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYN+AV
Subjt: LYQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAV
Query: IGGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVH
IGGHV+ NQIHLHISD+KNLE NG +P PEL L+PRLVVNSTGLSAVPLA+ FDGLH VIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVH
Subjt: IGGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVH
Query: VTLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLFGIE
VTLDLDGQVKFGPDVEWIDEVD ISSFLN+FDYSVRGSRAERFYEEIRKYYPSLK+GSLQSGYAGIRPKL+GPRQTPADFVIQGEEIHKVSGLINLFGIE
Subjt: VTLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLFGIE
Query: SPGLTSSLAIAEHLAAKYV
SPGLTSSLAIAEH+AA+Y+
Subjt: SPGLTSSLAIAEHLAAKYV
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| XP_011653836.1 L-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X1 [Cucumis sativus] | 1.9e-212 | 88.78 | Show/hide |
Query: MLKLAVQSLRGRSD-MVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDL
ML L VQSLRGR+ MV+++SSMA GTAKEKVDC+VIGAG+VGIAVARELSLRG+DVLVL+SAPTFGTGTSSRNSEVIHAGIYYPR+SLKAILCVRGRDL
Subjt: MLKLAVQSLRGRSD-MVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDL
Query: LYQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAV
LY+YCSE++IPHKQIGKLIVATRTSE+PKLNELL RGVQNGVEGL+MVDG+EAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYN+AV
Subjt: LYQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAV
Query: IGGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVH
IGGHV+ NQIHLHISD++NLE NG +P PEL L+P+LVVNSTGLSAVPLA+RF+GLH VIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVH
Subjt: IGGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVH
Query: VTLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLFGIE
VTLDLDGQVKFGPDVEWI EVD ISSFLN+FDYSVRGSRAERFYEEIRKYYPSLK+GSLQSGYAGIRPKL+GPRQTPADFVIQGEEIHKVSGLINLFGIE
Subjt: VTLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLFGIE
Query: SPGLTSSLAIAEHLAAKYV
SPGLTSSLAIAEH+AA+Y+
Subjt: SPGLTSSLAIAEHLAAKYV
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| XP_022154533.1 L-2-hydroxyglutarate dehydrogenase, mitochondrial [Momordica charantia] | 7.2e-220 | 91.63 | Show/hide |
Query: MLKLAVQSLRGRSDMVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLL
MLKLA +SLRGR+ M KK SSMAG AKEKVDCVVIGAGVVG+AVARELSLRG+DVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLL
Subjt: MLKLAVQSLRGRSDMVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLL
Query: YQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAVI
Y+YCSEHEIPHKQIGKLIVAT SEVPKLNELLSRGVQNGVEGL+MVDGDEAMRMEPELQCVKALLSPLSGI+DSHS MLSLVGEAENHG KFSYNTAVI
Subjt: YQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAVI
Query: GGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVHV
GGHVE NQ+HLHISDTKNLEKWNGED+ +PELML+PRLVVNSTGLSAVPLAKRFDGLH IPPSYYARGCYFTLSNVGV PFQRLIYPLPEDGGIGVHV
Subjt: GGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVHV
Query: TLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLFGIES
TLDLDGQVKFGPDVEWIDEVDGISSFLN++DYSV GSRAERFY+EIRKYYPSLKDGSLQSGYAGIRPKLTGP+QTPADFVIQGEEIH+VSGLINLFGIES
Subjt: TLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLFGIES
Query: PGLTSSLAIAEHLAAKYV
PGLTSSLAIAEH+AA+YV
Subjt: PGLTSSLAIAEHLAAKYV
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| XP_038882694.1 L-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X2 [Benincasa hispida] | 5.4e-215 | 90.19 | Show/hide |
Query: MLKLAVQSLRGRSDMVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLL
ML LAV+SLRGR+ M ++ISSMA GTAKEKVDCVVIGAGVVGIAVARELSLRG+DVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKA+LCVRGRDLL
Subjt: MLKLAVQSLRGRSDMVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLL
Query: YQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAVI
Y+YCSEHEIPHKQIGKLIVATRTSEVPKLNELL RGVQNGVEGL+MV G+EAMRMEPELQCVKALLSPLSGIVDSHS MLSLVGEAENHGAKFSYNTAVI
Subjt: YQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAVI
Query: GGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVHV
GGHV+ N+IHLHISD+KNLEK N + P PE ML+PRLVVNSTGLSAVPLAKRFDGLH VIPPSYYARGCYFTLSNVGV PFQRLIYPLPEDGGIGVHV
Subjt: GGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVHV
Query: TLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLFGIES
TLDLDGQVKFGPDVEWIDEVDGIS FLN+FDYSV SRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKL+GPRQTPADFVIQGE+IHKVSGL+NLFGIES
Subjt: TLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLFGIES
Query: PGLTSSLAIAEHLAAKYV
PGLTSSLAIAEH+AA Y+
Subjt: PGLTSSLAIAEHLAAKYV
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| XP_038882696.1 L-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X3 [Benincasa hispida] | 1.9e-196 | 90.13 | Show/hide |
Query: MLKLAVQSLRGRSDMVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLL
ML LAV+SLRGR+ M ++ISSMA GTAKEKVDCVVIGAGVVGIAVARELSLRG+DVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKA+LCVRGRDLL
Subjt: MLKLAVQSLRGRSDMVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLL
Query: YQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAVI
Y+YCSEHEIPHKQIGKLIVATRTSEVPKLNELL RGVQNGVEGL+MV G+EAMRMEPELQCVKALLSPLSGIVDSHS MLSLVGEAENHGAKFSYNTAVI
Subjt: YQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAVI
Query: GGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVHV
GGHV+ N+IHLHISD+KNLEK N + P PE ML+PRLVVNSTGLSAVPLAKRFDGLH VIPPSYYARGCYFTLSNVGV PFQRLIYPLPEDGGIGVHV
Subjt: GGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVHV
Query: TLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEE
TLDLDGQVKFGPDVEWIDEVDGIS FLN+FDYSV SRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKL+GPRQTPADFVIQ E
Subjt: TLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEE
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| TrEMBL top hits | e value | %identity | Alignment |
|---|
| A0A0A0L0R8 DAO domain-containing protein | 9.3e-213 | 88.78 | Show/hide |
Query: MLKLAVQSLRGRSD-MVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDL
ML L VQSLRGR+ MV+++SSMA GTAKEKVDC+VIGAG+VGIAVARELSLRG+DVLVL+SAPTFGTGTSSRNSEVIHAGIYYPR+SLKAILCVRGRDL
Subjt: MLKLAVQSLRGRSD-MVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDL
Query: LYQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAV
LY+YCSE++IPHKQIGKLIVATRTSE+PKLNELL RGVQNGVEGL+MVDG+EAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYN+AV
Subjt: LYQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAV
Query: IGGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVH
IGGHV+ NQIHLHISD++NLE NG +P PEL L+P+LVVNSTGLSAVPLA+RF+GLH VIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVH
Subjt: IGGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVH
Query: VTLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLFGIE
VTLDLDGQVKFGPDVEWI EVD ISSFLN+FDYSVRGSRAERFYEEIRKYYPSLK+GSLQSGYAGIRPKL+GPRQTPADFVIQGEEIHKVSGLINLFGIE
Subjt: VTLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLFGIE
Query: SPGLTSSLAIAEHLAAKYV
SPGLTSSLAIAEH+AA+Y+
Subjt: SPGLTSSLAIAEHLAAKYV
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| A0A1S3C1T2 L-2-hydroxyglutarate dehydrogenase, mitochondrial | 2.1e-212 | 89.26 | Show/hide |
Query: MLKLAVQSLRGRSD-MVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDL
ML VQ+LRGR+ M +KISSM GTAKEKVDC+VIGAG+VGIAVARELSLRG+DVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDL
Subjt: MLKLAVQSLRGRSD-MVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDL
Query: LYQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAV
LY+YCSE +IPHKQIGKLIVATRTSEVPKLNELL RGVQNGVEGL+MVD ++AMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYN+AV
Subjt: LYQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAV
Query: IGGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVH
IGGHV+ NQIHLHISD+KNLE NG +P PEL L+PRLVVNSTGLSAVPLA+ FDGLH VIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVH
Subjt: IGGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVH
Query: VTLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLFGIE
VTLDLDGQVKFGPDVEWIDEVD ISSFLN+FDYSVRGSRAERFYEEIRKYYPSLK+GSLQSGYAGIRPKL+GPRQTPADFVIQGEEIHKVSGLINLFGIE
Subjt: VTLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLFGIE
Query: SPGLTSSLAIAEHLAAKYV
SPGLTSSLAIAEH+AA+Y+
Subjt: SPGLTSSLAIAEHLAAKYV
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| A0A5N6RTS4 DAO domain-containing protein | 2.4e-176 | 76.02 | Show/hide |
Query: AKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLLYQYCSEHEIPHKQIGKLIVATRTSEV
A+E+ +CVVIGAGVVG+AVARELSLRG++VLVL+SAPTFGTGTSSRNS+VIHAGIYY +SLKAILCVRGR++LY+YCSEH+IPHKQIGKLIVAT TSE+
Subjt: AKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLLYQYCSEHEIPHKQIGKLIVATRTSEV
Query: PKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAVIGGHVEGNQIHLHISDTKNLEKWNGED
PKLN L++ G+QN V+GL+M++G EA RMEPELQCVKALLSP+SG+VD+HSLMLSLVGEAEN+ FSYNT VIG H+EGN I LH+S+TK+LE WNG
Subjt: PKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAVIGGHVEGNQIHLHISDTKNLEKWNGED
Query: IPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVHVTLDLDGQVKFGPDVEWIDEVDGISSF
+ PEL+LIP LVVNSTGLSA LA RFDGLH VIP +YYARGCYFTLSN +PPF LIYPLPEDGG+GVHVTLDLDGQVKFGPDVEWI+ +D IS F
Subjt: IPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVHVTLDLDGQVKFGPDVEWIDEVDGISSF
Query: LNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLFGIESPGLTSSLAIAEHLAAKYV
LNRFDYSV +RA++FY EIRKYYP+LKDGSL GYAG+RPK++GPR + ADF+IQGEEIH + GLINLFGIESPGLTSSLAIAEH+AA+++
Subjt: LNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLFGIESPGLTSSLAIAEHLAAKYV
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| A0A6J1DKK0 L-2-hydroxyglutarate dehydrogenase, mitochondrial | 3.5e-220 | 91.63 | Show/hide |
Query: MLKLAVQSLRGRSDMVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLL
MLKLA +SLRGR+ M KK SSMAG AKEKVDCVVIGAGVVG+AVARELSLRG+DVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLL
Subjt: MLKLAVQSLRGRSDMVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLL
Query: YQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAVI
Y+YCSEHEIPHKQIGKLIVAT SEVPKLNELLSRGVQNGVEGL+MVDGDEAMRMEPELQCVKALLSPLSGI+DSHS MLSLVGEAENHG KFSYNTAVI
Subjt: YQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAVI
Query: GGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVHV
GGHVE NQ+HLHISDTKNLEKWNGED+ +PELML+PRLVVNSTGLSAVPLAKRFDGLH IPPSYYARGCYFTLSNVGV PFQRLIYPLPEDGGIGVHV
Subjt: GGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGIGVHV
Query: TLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLFGIES
TLDLDGQVKFGPDVEWIDEVDGISSFLN++DYSV GSRAERFY+EIRKYYPSLKDGSLQSGYAGIRPKLTGP+QTPADFVIQGEEIH+VSGLINLFGIES
Subjt: TLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLFGIES
Query: PGLTSSLAIAEHLAAKYV
PGLTSSLAIAEH+AA+YV
Subjt: PGLTSSLAIAEHLAAKYV
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| A0A6J5XZC8 DAO domain-containing protein | 9.0e-176 | 71.46 | Show/hide |
Query: MLKLAVQSLR---GRSDMVKKI-----------SSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRN
MLK +QSL S +V KI SS + G KEKVDCVVIGAGVVG+AVAREL+L+G++VLVLESA TFGTGTSSRNSEVIHAGIYYP N
Subjt: MLKLAVQSLR---GRSDMVKKI-----------SSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRN
Query: SLKAILCVRGRDLLYQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEA
SLKAILCV+GR+LLY+YCSEH IPH QIGKLIVAT +SE+PKL+ L++ G++NGV GL M++G EA RMEPEL+C+KALLSP+SGIVD+HSLMLSLVGEA
Subjt: SLKAILCVRGRDLLYQYCSEHEIPHKQIGKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEA
Query: ENHGAKFSYNTAVIGGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRL
ENHG FSYNT VIGGH+E N++ LHIS+T++LE WNG+ +PE++LIP+LVVNS GLSA LAKRFDGL + VIPP+YYARGCYFTLSN + PF+ L
Subjt: ENHGAKFSYNTAVIGGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRL
Query: IYPLPEDGGIGVHVTLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEI
IYPLPEDGGIGVHVTLDL+GQVKFGP+VEWID +D ISSFLN+FDYSV +RA+ FY EIRKYYP+LKDGSL GYAGIRPKL+GPRQ+P DFVIQGE+I
Subjt: IYPLPEDGGIGVHVTLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEI
Query: HKVSGLINLFGIESPGLTSSLAIAEHLAAKY
H ++GL+NLFGIESPGLTSS+ +AEH+A ++
Subjt: HKVSGLINLFGIESPGLTSSLAIAEHLAAKY
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| SwissProt top hits | e value | %identity | Alignment |
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| A7MBI3 L-2-hydroxyglutarate dehydrogenase, mitochondrial | 3.0e-35 | 29.45 | Show/hide |
Query: DCVVIGAGVVGIAVARELSLR--GKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLLYQYCSEHEIPHKQIGKLIVATRTSEVPKL
D V+IG G+VG+A AR L LR + VLE + NS VIH+GIYY SLKA LCV+G L+Y+YC++ I +KQ GKLIVA E+P+L
Subjt: DCVVIGAGVVGIAVARELSLR--GKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLLYQYCSEHEIPHKQIGKLIVATRTSEVPKL
Query: NELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAVIGGHV---------EGNQIHLHISDTKNLE
L RG+QNGV+GL+++ ++ + EP + + A+ P +GIVD + S + + G N V + +G + + I +TK
Subjt: NELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAVIGGHV---------EGNQIHLHISDTKNLE
Query: KWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPED--GGIGVHVTLDLDGQVKFGPDVEWID
GE++ + VV GL + +++ G + P RG Y L + IYP+P+ +GVH T +DG + GP+
Subjt: KWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPED--GGIGVHVTLDLDGQVKFGPDVEWID
Query: EVDGISSF--------------------LNRFDYSVRGSRAERF----YEEIRKYYPSLKDGSLQSGYAGIRPK-LTGPRQTPADFVIQGEEIHKVSGLI
+ +G F F Y V F + ++K+ P + + G AG+R + L DFV G + ++
Subjt: EVDGISSF--------------------LNRFDYSVRGSRAERF----YEEIRKYYPSLKDGSLQSGYAGIRPK-LTGPRQTPADFVIQGEEIHKVSGLI
Query: NLFGIESPGLTSSLAIAEHLA
++ SP TSSLAI+ +A
Subjt: NLFGIESPGLTSSLAIAEHLA
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| A7SMW7 L-2-hydroxyglutarate dehydrogenase, mitochondrial | 3.3e-42 | 33.65 | Show/hide |
Query: EKVDCVVIGAGVVGIAVARELSLRGKDV--LVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLLYQYCSEHEIPHKQIGKLIVATRTSEV
E D ++G G+VG+A AREL LR + VLE S NS VIH GIYY SLKA LCV+G DL YQYC EH IP+K+ GKLIVA E+
Subjt: EKVDCVVIGAGVVGIAVARELSLRGKDV--LVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLLYQYCSEHEIPHKQIGKLIVATRTSEV
Query: PKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAVIGGHVEGNQIHLHISDTKNLEKWNGED
P LN L RG +NGV+ L MVD +EP + + A++SP +GIVD + L+ +G F I E K+ EK G
Subjt: PKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAVIGGHVEGNQIHLHISDTKNLEKWNGED
Query: IP-----KPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDG--GIGVHVTLDLDGQVKFGP-------
P + + R V+ GL + LA++ G + E P RG Y L + IYP+P+ +GVH T +DG V GP
Subjt: IP-----KPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDG--GIGVHVTLDLDGQVKFGP-------
Query: -------DVEWIDEVDGIS------SFLNRFDYSV----RGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPK-LTGPRQTPADFVIQGEEIHKVSGLIN
D+ D D ++ F + V RG ++++KY PS+ + SG +G+R + L DFV G S +++
Subjt: -------DVEWIDEVDGIS------SFLNRFDYSV----RGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPK-LTGPRQTPADFVIQGEEIHKVSGLIN
Query: LFGIESPGLTSSLAIAEHLAAK
+ SP TSSLAIA +A K
Subjt: LFGIESPGLTSSLAIAEHLAAK
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| Q5R9N7 L-2-hydroxyglutarate dehydrogenase, mitochondrial | 5.5e-37 | 30.67 | Show/hide |
Query: DCVVIGAGVVGIAVARELSLR--GKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLLYQYCSEHEIPHKQIGKLIVATRTSEVPKL
D V++G G+VG+A AR L LR + VLE + NS VIH+GIYY SLKA LCV+G LLY+YC + I +KQ GKLIVA E+P+L
Subjt: DCVVIGAGVVGIAVARELSLR--GKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLLYQYCSEHEIPHKQIGKLIVATRTSEVPKL
Query: NELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAV---------IGGHVEGNQIHLHISDTKNLE
L RG+QNGV+GL+++ D+ + EP + + A+ P +GIVD + LS + ++ G N V + ++G Q + I + K
Subjt: NELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAV---------IGGHVEGNQIHLHISDTKNLE
Query: KWNGEDIPKPELMLIPRL----VVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPED--GGIGVHVTLDLDGQVKFGPDV
GE+I ++ L + +G S P F G + + P CY N IYP+P+ +GVH TL +DG + GP+
Subjt: KWNGEDIPKPELMLIPRL----VVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPED--GGIGVHVTLDLDGQVKFGPDV
Query: EWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPK-LTGPRQTPADFVIQGEEIHKVSGLINLFGIESPGLTSSLAIAEHL
+ +G FD+S + D + G AG+R + L DFV + ++++ SP TSS+AI+ +
Subjt: EWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPK-LTGPRQTPADFVIQGEEIHKVSGLINLFGIESPGLTSSLAIAEHL
Query: A
A
Subjt: A
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| Q91YP0 L-2-hydroxyglutarate dehydrogenase, mitochondrial | 6.5e-38 | 30.17 | Show/hide |
Query: DCVVIGAGVVGIAVARELSLR--GKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLLYQYCSEHEIPHKQIGKLIVATRTSEVPKL
D V++G G+VG+A AR L L+ G + V+E + NS VIH+GIYY SLKA LCV G L+Y+YC+ IP++Q GKLIVA E+P+L
Subjt: DCVVIGAGVVGIAVARELSLR--GKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLLYQYCSEHEIPHKQIGKLIVATRTSEVPKL
Query: NELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAVIGGHV---------EGNQIHLHISDTKNLE
L RG+QNGVEGL+++ ++ + EP + + A+ P +GIV+ + LS + + G + V G + +G + + ++K E
Subjt: NELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLVGEAENHGAKFSYNTAVIGGHV---------EGNQIHLHISDTKNLE
Query: KWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPED--GGIGVHVTLDLDGQVKFGP------
+ R VV GL + +++ G + + P RG Y L + IYP+P+ +GVH T LDG + GP
Subjt: KWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPED--GGIGVHVTLDLDGQVKFGP------
Query: ----------DVEWIDEVDGISSFLN----RFDYSVRGSRAERFYEE----IRKYYPSLKDGSLQSGYAGIRPK-LTGPRQTPADFVIQGEEIHKVSGLI
D + EV S F+N F Y V F E ++K+ P + + G AG+R + L DFV G ++
Subjt: ----------DVEWIDEVDGISSFLN----RFDYSVRGSRAERFYEE----IRKYYPSLKDGSLQSGYAGIRPK-LTGPRQTPADFVIQGEEIHKVSGLI
Query: NLFGIESPGLTSSLAIAEHLA
++ SP TSSLAI+ +A
Subjt: NLFGIESPGLTSSLAIAEHLA
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| Q9LES4 L-2-hydroxyglutarate dehydrogenase, mitochondrial | 6.7e-152 | 64.22 | Show/hide |
Query: MVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLLYQYCSEHEIPHKQI
+V+ IS A AKE+VD VVIGAGVVG+AVARELSLRG++VL+L++A +FGT TSSRNSEV+HAGIYYP NSLKA CVRGR+LLY+YCSE+EIPHK+I
Subjt: MVKKISSMAGGTAKEKVDCVVIGAGVVGIAVARELSLRGKDVLVLESAPTFGTGTSSRNSEVIHAGIYYPRNSLKAILCVRGRDLLYQYCSEHEIPHKQI
Query: GKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLV------------------GEAENHGAKFSYN
GKLIVAT +SE+PKL+ L+ G QN V GL+M++G EAMRMEP+L+CVKALLSP SGI+D+HS MLSLV GEA+N+ A FSYN
Subjt: GKLIVATRTSEVPKLNELLSRGVQNGVEGLKMVDGDEAMRMEPELQCVKALLSPLSGIVDSHSLMLSLV------------------GEAENHGAKFSYN
Query: TAVIGGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGI
T V+ G VE ++HL+++DT+ E + +L LIP LVVNS GL A LAKR GL +P S+YARGCYFTLS + PPF +L+YP+PE+GG+
Subjt: TAVIGGHVEGNQIHLHISDTKNLEKWNGEDIPKPELMLIPRLVVNSTGLSAVPLAKRFDGLHAEVIPPSYYARGCYFTLSNVGVPPFQRLIYPLPEDGGI
Query: GVHVTLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLF
GVHVT+DL+G VKFGPDVEWI+ D SSFLN+FDY V R+E+FY EIRKYYP LKDGSL+ GY+GIRPKL+GP+Q+PADFVIQGEE H V GL+NLF
Subjt: GVHVTLDLDGQVKFGPDVEWIDEVDGISSFLNRFDYSVRGSRAERFYEEIRKYYPSLKDGSLQSGYAGIRPKLTGPRQTPADFVIQGEEIHKVSGLINLF
Query: GIESPGLTSSLAIAEHLAAKYV
GIESPGLTSSLAIAEH+A K++
Subjt: GIESPGLTSSLAIAEHLAAKYV
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