| GenBank top hits | e value | %identity | Alignment |
|---|
| KAA0040348.1 (RS)-norcoclaurine 6-O-methyltransferase-like [Cucumis melo var. makuwa] | 1.2e-154 | 76.86 | Show/hide |
Query: DIGSKDSNFRK-EEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQ
D G+K+SN K EEE+S+++V+VWKYIFGFVEMAV+KCAIELKI D IESHG ITL QLSS+ +CS P LLHR++RFLVHRGIFKEE ++ S Y+
Subjt: DIGSKDSNFRK-EEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQ
Query: TAMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKA----NGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVG
T MSRLLT+ G NS+API LLE SPVM+APWHNLSA +KA NG+ PFEMAHG DLW+YAA +PSH+ L+NEGMACFAR+ ILPAVLE+CGEIF+GVG
Subjt: TAMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKA----NGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVG
Query: SLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVID
LVDVGGGNGTCLSILVKACPWI+GINFDLPHVVSVS+EYEGVQH+GG+MFD +PKADAAFIMEVLHDWDDEECIKIL+NCKEAIPE TGKVIIVE+VID
Subjt: SLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVID
Query: EKEE--SKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
EKE+ SK SDV+L MDMIMMAHT KGKERT EEW N+LQKAGFS YTITPT TIQSVIQ FP
Subjt: EKEE--SKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
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| XP_004144871.1 acetylserotonin O-methyltransferase [Cucumis sativus] | 1.4e-155 | 77.9 | Show/hide |
Query: DIGSKDSNFRK-EEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQ
D SK SN K EEEDS+++V++WKYIFGFVEMAVIKCAIELKI D IESHG +TL QLSS+ NCS P LLHR++RFLVHRGIFKEE Y+
Subjt: DIGSKDSNFRK-EEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQ
Query: TAMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKA----NGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVG
T MSRLLT+ G NS+AP+ LLE SPVM+APWHNLSA +KA NG+ PFEMAHG DLW+YAA +PSH+ L+NE MACFAR+ ILPAVLE+CGEIF+GVG
Subjt: TAMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKA----NGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVG
Query: SLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVID
LVDVGGGNGTCLSILVKACPWI+GINFDLPHVVSVS+EYEG+QH+GGNMFD +PKADAAFIMEVLHDWDDEECIKILKNCKEAIPE TGKVIIVEVVID
Subjt: SLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVID
Query: EKEE-SKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
EKEE SK SD RLMMDMIMMAHT KGKERT EEW NVLQKAGFS YTITPT TIQSVIQ FP
Subjt: EKEE-SKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
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| XP_008447905.1 PREDICTED: (RS)-norcoclaurine 6-O-methyltransferase-like [Cucumis melo] | 2.6e-154 | 76.58 | Show/hide |
Query: DIGSKDSNFRK-EEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQ
D G+K+SN K EEE+S+++V+VWKYIFGFVEMAV+KCAIELKI D IESHG +TL QLSS+ +CS P LLHR++RFLVHRGIFKEE ++ S Y+
Subjt: DIGSKDSNFRK-EEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQ
Query: TAMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKA----NGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVG
T MSRLLT+ G NS+API LLE SPVM+APWHNLSA +KA NG+ PFEMAHG DLW+YAA +PSH+ L+NEGMACFAR+ ILPAVLE+CGEIF+GVG
Subjt: TAMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKA----NGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVG
Query: SLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVID
LVDVGGGNGTCLSILVKACPWI+GINFDLPHVVSVS+EYEGVQH+GG+MFD +PKADAAFIMEVLHDWDDEECIKIL+NCKEAIPE TGKVIIVE+VID
Subjt: SLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVID
Query: EKEE--SKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
EKE+ SK SDV+L MDMIMMAHT KGKERT EEW N+LQKAGFS YTITPT TIQSVIQ FP
Subjt: EKEE--SKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
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| XP_022135686.1 (R,S)-reticuline 7-O-methyltransferase-like [Momordica charantia] | 5.5e-160 | 81.32 | Show/hide |
Query: RKEEED-SEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQTAMSRLLTS
+KE+ED SE R +VWKYIFGFVEMAVIKCAIELKI DAIESHGSPITLPQLSSA CS PS LHRV+RFLVHRGIFKEE A G+ GY QT MSRLLTS
Subjt: RKEEED-SEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQTAMSRLLTS
Query: GGENSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVGSLVDVGGGNGTCL
++S+AP+LLLE +PVMLAPWH LSAFLK + T PFE AHG+DLWSYAA DPS ML+NE MACFAR+ I+PAV+E+CGEIFEGVGSLVDVGGGNGTCL
Subjt: GGENSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVGSLVDVGGGNGTCL
Query: SILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEKEESKLSDVRLM
SILVKA PWIRGINFDLPHVV VS YEGV+H+GGNMFDC+PKADAAFIMEVLHDWDDEECIK+LKNCKEAIP+ TGKVIIVE+VIDEKE++KL DVRLM
Subjt: SILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEKEESKLSDVRLM
Query: MDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
MDMIMMAHT KGKERTREEW VLQKAGFSRY ITPT TIQSVIQ FP
Subjt: MDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
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| XP_022969151.1 (RS)-norcoclaurine 6-O-methyltransferase-like isoform X1 [Cucurbita maxima] | 5.3e-155 | 77.31 | Show/hide |
Query: DIGSKDSNFRKEEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQT
+IGSKDS F++EEE ++++++VWKYIFGFVEMAVIKCAIELKIAD I++HG +TLP+LSS+ NCS P LL R++RFL+HRGIFKEE + YAQT
Subjt: DIGSKDSNFRKEEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQT
Query: AMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKAN--GTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVGSLV
MSRLLTS G +SLAPI +LE S VMLAPWHNLSA+LKAN GT PFEMAHGKDLWSY A + SHNM++NEGMA F+RV I+PAVLE+CG +FEGVGSLV
Subjt: AMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKAN--GTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVGSLV
Query: DVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEKE
DVGGGNG+CLS+LVKA PWIRGINFDLPHVVSVSQEYEGV+H+GGNMFD +PKADAAFIM LHDWDDEECIKILKNCKEAIPE TGKVIIVEVVIDEKE
Subjt: DVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEKE
Query: ESKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGF
ES +SDVRLM+DMIM+AHT KGKERTREEW VLQ AGFSR+TITPT TIQS+IQGF
Subjt: ESKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGF
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| TrEMBL top hits | e value | %identity | Alignment |
|---|
| A0A0A0K0Q2 Uncharacterized protein | 6.8e-156 | 77.9 | Show/hide |
Query: DIGSKDSNFRK-EEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQ
D SK SN K EEEDS+++V++WKYIFGFVEMAVIKCAIELKI D IESHG +TL QLSS+ NCS P LLHR++RFLVHRGIFKEE Y+
Subjt: DIGSKDSNFRK-EEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQ
Query: TAMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKA----NGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVG
T MSRLLT+ G NS+AP+ LLE SPVM+APWHNLSA +KA NG+ PFEMAHG DLW+YAA +PSH+ L+NE MACFAR+ ILPAVLE+CGEIF+GVG
Subjt: TAMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKA----NGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVG
Query: SLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVID
LVDVGGGNGTCLSILVKACPWI+GINFDLPHVVSVS+EYEG+QH+GGNMFD +PKADAAFIMEVLHDWDDEECIKILKNCKEAIPE TGKVIIVEVVID
Subjt: SLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVID
Query: EKEE-SKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
EKEE SK SD RLMMDMIMMAHT KGKERT EEW NVLQKAGFS YTITPT TIQSVIQ FP
Subjt: EKEE-SKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
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| A0A1S3BHY1 (RS)-norcoclaurine 6-O-methyltransferase-like | 1.3e-154 | 76.58 | Show/hide |
Query: DIGSKDSNFRK-EEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQ
D G+K+SN K EEE+S+++V+VWKYIFGFVEMAV+KCAIELKI D IESHG +TL QLSS+ +CS P LLHR++RFLVHRGIFKEE ++ S Y+
Subjt: DIGSKDSNFRK-EEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQ
Query: TAMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKA----NGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVG
T MSRLLT+ G NS+API LLE SPVM+APWHNLSA +KA NG+ PFEMAHG DLW+YAA +PSH+ L+NEGMACFAR+ ILPAVLE+CGEIF+GVG
Subjt: TAMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKA----NGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVG
Query: SLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVID
LVDVGGGNGTCLSILVKACPWI+GINFDLPHVVSVS+EYEGVQH+GG+MFD +PKADAAFIMEVLHDWDDEECIKIL+NCKEAIPE TGKVIIVE+VID
Subjt: SLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVID
Query: EKEE--SKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
EKE+ SK SDV+L MDMIMMAHT KGKERT EEW N+LQKAGFS YTITPT TIQSVIQ FP
Subjt: EKEE--SKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
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| A0A5D3DI94 (RS)-norcoclaurine 6-O-methyltransferase-like | 5.8e-155 | 76.86 | Show/hide |
Query: DIGSKDSNFRK-EEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQ
D G+K+SN K EEE+S+++V+VWKYIFGFVEMAV+KCAIELKI D IESHG ITL QLSS+ +CS P LLHR++RFLVHRGIFKEE ++ S Y+
Subjt: DIGSKDSNFRK-EEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQ
Query: TAMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKA----NGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVG
T MSRLLT+ G NS+API LLE SPVM+APWHNLSA +KA NG+ PFEMAHG DLW+YAA +PSH+ L+NEGMACFAR+ ILPAVLE+CGEIF+GVG
Subjt: TAMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKA----NGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVG
Query: SLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVID
LVDVGGGNGTCLSILVKACPWI+GINFDLPHVVSVS+EYEGVQH+GG+MFD +PKADAAFIMEVLHDWDDEECIKIL+NCKEAIPE TGKVIIVE+VID
Subjt: SLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVID
Query: EKEE--SKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
EKE+ SK SDV+L MDMIMMAHT KGKERT EEW N+LQKAGFS YTITPT TIQSVIQ FP
Subjt: EKEE--SKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
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| A0A6J1C1G3 (R,S)-reticuline 7-O-methyltransferase-like | 2.7e-160 | 81.32 | Show/hide |
Query: RKEEED-SEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQTAMSRLLTS
+KE+ED SE R +VWKYIFGFVEMAVIKCAIELKI DAIESHGSPITLPQLSSA CS PS LHRV+RFLVHRGIFKEE A G+ GY QT MSRLLTS
Subjt: RKEEED-SEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQTAMSRLLTS
Query: GGENSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVGSLVDVGGGNGTCL
++S+AP+LLLE +PVMLAPWH LSAFLK + T PFE AHG+DLWSYAA DPS ML+NE MACFAR+ I+PAV+E+CGEIFEGVGSLVDVGGGNGTCL
Subjt: GGENSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVGSLVDVGGGNGTCL
Query: SILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEKEESKLSDVRLM
SILVKA PWIRGINFDLPHVV VS YEGV+H+GGNMFDC+PKADAAFIMEVLHDWDDEECIK+LKNCKEAIP+ TGKVIIVE+VIDEKE++KL DVRLM
Subjt: SILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEKEESKLSDVRLM
Query: MDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
MDMIMMAHT KGKERTREEW VLQKAGFSRY ITPT TIQSVIQ FP
Subjt: MDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
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| A0A6J1HWX9 (RS)-norcoclaurine 6-O-methyltransferase-like isoform X1 | 2.6e-155 | 77.31 | Show/hide |
Query: DIGSKDSNFRKEEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQT
+IGSKDS F++EEE ++++++VWKYIFGFVEMAVIKCAIELKIAD I++HG +TLP+LSS+ NCS P LL R++RFL+HRGIFKEE + YAQT
Subjt: DIGSKDSNFRKEEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQT
Query: AMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKAN--GTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVGSLV
MSRLLTS G +SLAPI +LE S VMLAPWHNLSA+LKAN GT PFEMAHGKDLWSY A + SHNM++NEGMA F+RV I+PAVLE+CG +FEGVGSLV
Subjt: AMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKAN--GTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVGSLV
Query: DVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEKE
DVGGGNG+CLS+LVKA PWIRGINFDLPHVVSVSQEYEGV+H+GGNMFD +PKADAAFIM LHDWDDEECIKILKNCKEAIPE TGKVIIVEVVIDEKE
Subjt: DVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEKE
Query: ESKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGF
ES +SDVRLM+DMIM+AHT KGKERTREEW VLQ AGFSR+TITPT TIQS+IQGF
Subjt: ESKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGF
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| SwissProt top hits | e value | %identity | Alignment |
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| B0ZB56 Xanthohumol 4-O-methyltransferase | 2.8e-74 | 43.45 | Show/hide |
Query: RKEEEDSEVR--VRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSL----LHRVMRFLVHRGIFKEETAADSGLIGYAQTAMS
R ++ ++ +R VWK I G + V+KCA+EL+I D + SH +PITL Q++S+ S PSL L R+MR LV R IF + + D + Y T S
Subjt: RKEEEDSEVR--VRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPSL----LHRVMRFLVHRGIFKEETAADSGLIGYAQTAMS
Query: RLL----TSGGENSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAH-GKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVGSLV
RLL T + +LAP + P + APW L+ +K G FEM H G+ LW + G+P N + N+GMA AR+ + A+L + ++F G+ SLV
Subjt: RLL----TSGGENSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAH-GKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVGSLV
Query: DVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEG-VQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEK
DVGG G +S +VK+ P I+GIN+DLPHVV+ + Y G V H+GGNMF+ IP A A F+ +LHDW DE+C+KILKNC+ A+PE GK+IIV++V++ +
Subjt: DVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEG-VQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEK
Query: EESKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
D +M+D+ +MA T +GKERT +EW VL++ GF RY I + SVI+ +P
Subjt: EESKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
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| Q6WUC1 (RS)-norcoclaurine 6-O-methyltransferase | 9.4e-70 | 41.04 | Show/hide |
Query: DSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDP---SLLHRVMRFLVHRGIFKEETAADSGLIGYAQTAMSRLLTSGGE
D + + ++WK I+GF E V+KCA++L+IA+ + ++ P++L +L+S + P L R+MR+LVH +FK + Y+ ++ L G E
Subjt: DSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDP---SLLHRVMRFLVHRGIFKEETAADSGLIGYAQTAMSRLLTSGGE
Query: NSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIF-EGVGSLVDVGGGNGTCLSI
S+ +L LAPWH+L L N FE A GK +W Y + +P N L N MAC R+ + A+ +C IF +G+ +LVDVGGG GT +
Subjt: NSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIF-EGVGSLVDVGGGNGTCLSI
Query: LVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEKEESKLSDVRLMMD
+ KA P I+ +DLPHV++ S E + I G+MF IP ADA F+ +LHDW+D+ECI+ILK CKEA+P+G GKVIIV+VVID + +RL +D
Subjt: LVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEKEESKLSDVRLMMD
Query: MIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
+ MM +T GKERT+EEW + AGF+ + +T +QSVI+ +P
Subjt: MIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
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| Q6WUC2 (R,S)-reticuline 7-O-methyltransferase | 5.3e-73 | 41.19 | Show/hide |
Query: EEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPS------LLHRVMRFLVHRGIFKEETAADSGLIGYAQTAMSRLL
EE + + +W+++F FV+ +KCA+EL I D I SHG P+T+ ++ + + PS L R+MR LVH+ +F E +S + Y T S+ L
Subjt: EEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSSATNCSDPS------LLHRVMRFLVHRGIFKEETAADSGLIGYAQTAMSRLL
Query: TSGGENSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGV-GSLVDVGGGNG
+ +L+P++L E +P++L PW L + ++PFE AHG ++W A DP N +N M C + I+ +L + + F G+ GSLVDVGGG G
Subjt: TSGGENSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGV-GSLVDVGGGNG
Query: TCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAI-PEGTGKVIIVEVVIDEKEESKLSD
+ ++ +VKA P I+GINFDLPHVV+ + E+ GV+H+GG+MF IP+ADA + +LHDW DE+C ILKNC AI + GKVIIV+ V+
Subjt: TCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAI-PEGTGKVIIVEVVIDEKEESKLSD
Query: VRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
+ L+ D++MMAHT GKERT EW +L AGF RY + T +I+ FP
Subjt: VRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
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| Q7XB10 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase 2 | 7.7e-72 | 39.94 | Show/hide |
Query: EEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSS---ATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQTAMSRLLTS
+E + + ++W I+GF + V++CA+E+ IAD I+++ ITL QL++ TN S L+R++R+LVH I ++ET Y+ + LL
Subjt: EEEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGSPITLPQLSS---ATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQTAMSRLLTS
Query: GGENSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVGSLVDVGGGNGTCL
E S+ P++L + WH + L TT FE G D+W Y G+P + L NEGMA R+ + ++E C + F+G+ SLVD+GGGNGT +
Subjt: GGENSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVGSLVDVGGGNGTCL
Query: SILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEKEESKLSDVRLM
+ +A P I+ +DLPHVV+ S + ++ + G+MF +P A A + +LHDW DEEC+ ILK CKEAIP+ TGKVIIV+V ++E+ +L+ RL+
Subjt: SILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEKEESKLSDVRLM
Query: MDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
+D+ M+ +T G+ERT ++W N+L++AGF + I P R IQSVI+ FP
Subjt: MDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVIQGFP
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| Q9T003 Acetylserotonin O-methyltransferase | 3.4e-96 | 49.87 | Show/hide |
Query: MDIGSKDSNFRKE-EEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGS--PITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIG
+D + N RK +E+++ + +WKY+FGF ++A KCAI+LKI +AIE+H S P+TL +LSSA + S PS L R+MRFLVH+GIFKE D G
Subjt: MDIGSKDSNFRKE-EEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGS--PITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIG
Query: YAQTAMSR--LLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKA--NGTT--PFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEI
Y T +SR ++T SLAP +L E +P MLAPW LS+ + + NG+T PF+ HGKD+WS+A +P + ++NE MAC AR ++P V C +
Subjt: YAQTAMSR--LLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKA--NGTT--PFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEI
Query: FEGVGSLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIV
F+GV ++VDVGGG G + +LVK PWI+G NFDLPHV+ V++ +GV+++ G+MFD IP DA FI VLHDW D++CIKILKNCKEA+P GKV+IV
Subjt: FEGVGSLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIV
Query: E---------VVIDEKEESKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVI
E +++DE++E KL VRLM+DM+MMAHT GKERT +EW VL++AGF+RY + +QS+I
Subjt: E---------VVIDEKEESKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVI
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| Arabidopsis top hits | e value | %identity | Alignment |
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| AT1G51990.1 O-methyltransferase family protein | 2.4e-44 | 32.66 | Show/hide |
Query: IGSKDSNFRKEEEDSEVRVRVWKYIFGFVEMAVIKCAIELKI------ADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGI-----FKEETAA
I + S EEED + +++ FV ++K A EL + A + S+ SP+ L +++ N P ++ R++RFLV + K+E
Subjt: IGSKDSNFRKEEEDSEVRVRVWKYIFGFVEMAVIKCAIELKI------ADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGI-----FKEETAA
Query: DSGLIGYAQTAMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEI
+S G + +L+ S+AP +L + W L+ ++ G + +E A+ ++ Y + + + NE M + ++ +LE
Subjt: DSGLIGYAQTAMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEI
Query: FEGVGSLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIV
FEGV VDVGG G+ L+ ++ P I+GINFDLPH+V + + GV+HIGG+MFD IP+ + + +LHDW+DE+C++ILKNCK+A+PE TG++I++
Subjt: FEGVGSLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIV
Query: EVVID-EKEESKLSDVR-LMMDMIMMAHTKKGKERTREEWINVLQKAGF
E+++ E E+ L+ L D+ MM+ T GKERT++E+ ++ ++AGF
Subjt: EVVID-EKEESKLSDVR-LMMDMIMMAHTKKGKERTREEWINVLQKAGF
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| AT1G51990.2 O-methyltransferase family protein | 4.8e-45 | 32.66 | Show/hide |
Query: IGSKDSNFRKEEEDSEVRVRVWKYIFGFVEMAVIKCAIELKI------ADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGI-----FKEETAA
I + S EEED + +++ FV ++K A EL + A + S+ SP+ L +++ N P ++ R++RFLV + K+E
Subjt: IGSKDSNFRKEEEDSEVRVRVWKYIFGFVEMAVIKCAIELKI------ADAIESHGSPITLPQLSSATNCSDPSLLHRVMRFLVHRGI-----FKEETAA
Query: DSGLIGYAQTAMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEI
+S G + +L+ S+AP +L + W+N+ ++ G + +E A+ ++ Y + + + NE M + ++ +LE
Subjt: DSGLIGYAQTAMSRLLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEI
Query: FEGVGSLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIV
FEGV VDVGG G+ L+ ++ P I+GINFDLPH+V + + GV+HIGG+MFD IP+ + + +LHDW+DE+C++ILKNCK+A+PE TG++I++
Subjt: FEGVGSLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIV
Query: EVVID-EKEESKLSDVR-LMMDMIMMAHTKKGKERTREEWINVLQKAGF
E+++ E E+ L+ L D+ MM+ T GKERT++E+ ++ ++AGF
Subjt: EVVID-EKEESKLSDVR-LMMDMIMMAHTKKGKERTREEWINVLQKAGF
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| AT4G35150.1 O-methyltransferase family protein | 4.9e-82 | 45.43 | Show/hide |
Query: EEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGS--PITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQTAMSRLLTSGG
+E+++ + +W+Y+FGF ++A KCAI+LKI +AIE+H S P+TL +LSSA + S PS L R+MRFLVH+G+FKE D GY T +SR +
Subjt: EEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGS--PITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIGYAQTAMSRLLTSGG
Query: ENSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVGSLVDVGGGNGTCLSI
HGKDLW++A + H+ L+NE MAC AR ++P V C +F+GV ++VDVGGG G + I
Subjt: ENSLAPILLLEGSPVMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVGSLVDVGGGNGTCLSI
Query: LVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEKE--------ESKL
LVK PWI+G NFDLPHV+ V+Q +GV+++ G+MFD IP +DA I VLHDW D++CIKILKNCKEA+ GKV+IVE VI EK+ + KL
Subjt: LVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEKE--------ESKL
Query: SDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVI
VRL +DM+MM HT GKERT +EW VL +AGF+RY + +QS+I
Subjt: SDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVI
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| AT4G35160.1 O-methyltransferase family protein | 2.4e-97 | 49.87 | Show/hide |
Query: MDIGSKDSNFRKE-EEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGS--PITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIG
+D + N RK +E+++ + +WKY+FGF ++A KCAI+LKI +AIE+H S P+TL +LSSA + S PS L R+MRFLVH+GIFKE D G
Subjt: MDIGSKDSNFRKE-EEDSEVRVRVWKYIFGFVEMAVIKCAIELKIADAIESHGS--PITLPQLSSATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIG
Query: YAQTAMSR--LLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKA--NGTT--PFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEI
Y T +SR ++T SLAP +L E +P MLAPW LS+ + + NG+T PF+ HGKD+WS+A +P + ++NE MAC AR ++P V C +
Subjt: YAQTAMSR--LLTSGGENSLAPILLLEGSPVMLAPWHNLSAFLKA--NGTT--PFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEI
Query: FEGVGSLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIV
F+GV ++VDVGGG G + +LVK PWI+G NFDLPHV+ V++ +GV+++ G+MFD IP DA FI VLHDW D++CIKILKNCKEA+P GKV+IV
Subjt: FEGVGSLVDVGGGNGTCLSILVKACPWIRGINFDLPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIV
Query: E---------VVIDEKEESKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVI
E +++DE++E KL VRLM+DM+MMAHT GKERT +EW VL++AGF+RY + +QS+I
Subjt: E---------VVIDEKEESKLSDVRLMMDMIMMAHTKKGKERTREEWINVLQKAGFSRYTITPTRTIQSVI
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| AT5G54160.1 O-methyltransferase 1 | 3.2e-49 | 35.35 | Show/hide |
Query: IKCAIELKIADAIESHGSPITLPQLSS---ATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIG------YAQTAMSRLLTSGGEN-SLAPILLLEGSP
+K A+EL + + + +GSP++ +++S N P +L R++R L + T ++ L G Y + + LT + S+A + L+
Subjt: IKCAIELKIADAIESHGSPITLPQLSS---ATNCSDPSLLHRVMRFLVHRGIFKEETAADSGLIG------YAQTAMSRLLTSGGEN-SLAPILLLEGSP
Query: VMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVGSLVDVGGGNGTCLSILVKACPWIRGINFD
V++ W++L + +G PF A+G + Y DP N + N GM+ + + + +LE + FEG+ SLVDVGGG G L ++V P ++GINFD
Subjt: VMLAPWHNLSAFLKANGTTPFEMAHGKDLWSYAAGDPSHNMLVNEGMACFARVEILPAVLEKCGEIFEGVGSLVDVGGGNGTCLSILVKACPWIRGINFD
Query: LPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEKEESKLSDVRLM-MDMIMMAHTKKGKER
LPHV+ + + G++H+GG+MF +PK DA F+ + HDW DE C+K LKNC E++PE GKVI+ E ++ E +S LS +++ +D IM+AH GKER
Subjt: LPHVVSVSQEYEGVQHIGGNMFDCIPKADAAFIMEVLHDWDDEECIKILKNCKEAIPEGTGKVIIVEVVIDEKEESKLSDVRLM-MDMIMMAHTKKGKER
Query: TREEWINVLQKAGF
T +E+ + + +GF
Subjt: TREEWINVLQKAGF
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