CuGenDBv2

Gene ID	Spg014485
Organism	Luffa cylindrica (Sponge gourd (cylindrica) v1)
Description	Non-specific serine/threonine protein kinase
Genome location	scaffold3:37507919..37512227
RNA-Seq Expression	Spg014485
Synteny	Spg014485
Gene Ontology terms	GO:0006521 - regulation of cellular amino acid metabolic process (biological process) GO:0009635 - response to herbicide (biological process) GO:0010998 - regulation of translational initiation by eIF2 alpha phosphorylation (biological process) GO:0018105 - peptidyl-serine phosphorylation (biological process) GO:0005886 - plasma membrane (cellular component) GO:0000049 - tRNA binding (molecular function) GO:0004694 - eukaryotic translation initiation factor 2alpha kinase activity (molecular function) GO:0004712 - protein serine/threonine/tyrosine kinase activity (molecular function) GO:0005524 - ATP binding (molecular function) GO:0106310 - protein serine kinase activity (molecular function)
InterPro domains	NA

Homology

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GenBank top hits

e value

%identity

Alignment

KAG7025394.1 eIF-2-alpha kinase GCN2, partial [Cucurbita argyrosperma subsp. argyrosperma]

2.1e-65

86.39

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Query:  YEVLIPAQDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKK
        +EVLI AQDSI+ DH AED+DHG ESEPSEWSFAS+S EQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYN G+LSKVALDLASKPSSMFHKK
Subjt:  YEVLIPAQDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKK

Query:  FETAFRDQMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN
        FE+AF+++MN+TSFS+FWNPSDFGGPTSSQLSSRYL+DFEELK LG+
Subjt:  FETAFRDQMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN

XP_022150409.1 eIF-2-alpha kinase GCN2 isoform X1 [Momordica charantia]

2.9e-67

88.44

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Query:  YEVLIPAQDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKK
        ++V +PAQDSILTDHVAED+DHG ESEPSEWSFASLSN+QESQTT+RDIMMVHLLHLACAPKGPLADALPKLASELYN GVLS+VALDL SKPSSMFHKK
Subjt:  YEVLIPAQDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKK

Query:  FETAFRDQMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN
        FETAF++QMN+TSFSQFWNPSDFGGPTSSQLSSRYL+DFEELK LG+
Subjt:  FETAFRDQMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN

XP_022150410.1 eIF-2-alpha kinase GCN2 isoform X2 [Momordica charantia]

2.9e-67

88.44

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Query:  YEVLIPAQDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKK
        ++V +PAQDSILTDHVAED+DHG ESEPSEWSFASLSN+QESQTT+RDIMMVHLLHLACAPKGPLADALPKLASELYN GVLS+VALDL SKPSSMFHKK
Subjt:  YEVLIPAQDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKK

Query:  FETAFRDQMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN
        FETAF++QMN+TSFSQFWNPSDFGGPTSSQLSSRYL+DFEELK LG+
Subjt:  FETAFRDQMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN

XP_038885259.1 eIF-2-alpha kinase GCN2 isoform X3 [Benincasa hispida]

8.7e-64

86.39

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Query:  YEVLIPAQDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKK
        +EVLIP QDSILT +VAE +DHG ESEPSEWSFASL+NEQESQT DRDIMMVHLLHLACAPKGPLADALPKLASELYN GVLSKVALDLASKPSS FHKK
Subjt:  YEVLIPAQDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKK

Query:  FETAFRDQMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN
        F+TAF++QMN+TSFSQFWNPSDFGG  SSQLSSRYL+DFEELK LG+
Subjt:  FETAFRDQMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN

XP_038885260.1 eIF-2-alpha kinase GCN2 isoform X4 [Benincasa hispida]

8.7e-64

86.39

Show/hide

Query:  YEVLIPAQDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKK
        +EVLIP QDSILT +VAE +DHG ESEPSEWSFASL+NEQESQT DRDIMMVHLLHLACAPKGPLADALPKLASELYN GVLSKVALDLASKPSS FHKK
Subjt:  YEVLIPAQDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKK

Query:  FETAFRDQMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN
        F+TAF++QMN+TSFSQFWNPSDFGG  SSQLSSRYL+DFEELK LG+
Subjt:  FETAFRDQMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN

TrEMBL top hits

e value

%identity

Alignment

A0A6J1D8E1 Non-specific serine/threonine protein kinase

1.4e-67

88.44

Show/hide

Query:  YEVLIPAQDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKK
        ++V +PAQDSILTDHVAED+DHG ESEPSEWSFASLSN+QESQTT+RDIMMVHLLHLACAPKGPLADALPKLASELYN GVLS+VALDL SKPSSMFHKK
Subjt:  YEVLIPAQDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKK

Query:  FETAFRDQMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN
        FETAF++QMN+TSFSQFWNPSDFGGPTSSQLSSRYL+DFEELK LG+
Subjt:  FETAFRDQMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN

A0A6J1D9Z7 Non-specific serine/threonine protein kinase

1.4e-67

88.44

Show/hide

Query:  YEVLIPAQDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKK
        ++V +PAQDSILTDHVAED+DHG ESEPSEWSFASLSN+QESQTT+RDIMMVHLLHLACAPKGPLADALPKLASELYN GVLS+VALDL SKPSSMFHKK
Subjt:  YEVLIPAQDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKK

Query:  FETAFRDQMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN
        FETAF++QMN+TSFSQFWNPSDFGGPTSSQLSSRYL+DFEELK LG+
Subjt:  FETAFRDQMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN

A0A6J1H5V7 Non-specific serine/threonine protein kinase

2.7e-63

87.14

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Query:  QDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKKFETAFRD
        QDSI+ DH AED+DHG ESEPSEWSFAS+S EQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYN G+LSKVALDLASKPSSMFHKKFE+AF++
Subjt:  QDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKKFETAFRD

Query:  QMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN
        +MN+TSFS+FWNPSDFGGPTSSQLSSRYL+DFEELK LG+
Subjt:  QMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN

A0A6J1H7A8 Non-specific serine/threonine protein kinase

2.7e-63

87.14

Show/hide

Query:  QDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKKFETAFRD
        QDSI+ DH AED+DHG ESEPSEWSFAS+S EQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYN G+LSKVALDLASKPSSMFHKKFE+AF++
Subjt:  QDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKKFETAFRD

Query:  QMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN
        +MN+TSFS+FWNPSDFGGPTSSQLSSRYL+DFEELK LG+
Subjt:  QMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN

A0A6J1KZ64 Non-specific serine/threonine protein kinase

1.3e-62

86.43

Show/hide

Query:  QDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKKFETAFRD
        QDSI+ DH AED+DHG ESEPSEWSFAS+S EQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYN G+LSKVALDLASKPSS FHKKFE+AF++
Subjt:  QDSILTDHVAEDEDHGYESEPSEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKKFETAFRD

Query:  QMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN
        +MN+TSFS+FWNPSDFGGPTSSQLSSRYL+DFEELK LG+
Subjt:  QMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSLGN

SwissProt top hits

e value

%identity

Alignment

Q9LX30 eIF-2-alpha kinase GCN2

4.2e-29

51.77

Show/hide

Query:  QDSILTDHVAEDEDHGYESEP-SEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKKFETAFR
        ++S L D  AED+    ESE    WS  SL+ +Q  Q + +D++MVHLL +AC  +GPLADALP++  EL+  G+LS+  LDLASK S  F++ FE AF 
Subjt:  QDSILTDHVAEDEDHGYESEP-SEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKKFETAFR

Query:  DQMNSTSFSQFWN-PSDFGGPTSSQLSSRYLSDFEELKSLG
          M STS  QFW  PSD   P +S  SSRYL+DFEELK LG
Subjt:  DQMNSTSFSQFWN-PSDFGGPTSSQLSSRYLSDFEELKSLG

Arabidopsis top hits

e value

%identity

Alignment

AT3G59410.1 protein kinase family protein

3.0e-30

51.77

Show/hide

Query:  QDSILTDHVAEDEDHGYESEP-SEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKKFETAFR
        ++S L D  AED+    ESE    WS  SL+ +Q  Q + +D++MVHLL +AC  +GPLADALP++  EL+  G+LS+  LDLASK S  F++ FE AF 
Subjt:  QDSILTDHVAEDEDHGYESEP-SEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKKFETAFR

Query:  DQMNSTSFSQFWN-PSDFGGPTSSQLSSRYLSDFEELKSLG
          M STS  QFW  PSD   P +S  SSRYL+DFEELK LG
Subjt:  DQMNSTSFSQFWN-PSDFGGPTSSQLSSRYLSDFEELKSLG

AT3G59410.2 protein kinase family protein

3.0e-30

51.77

Show/hide

Query:  QDSILTDHVAEDEDHGYESEP-SEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKKFETAFR
        ++S L D  AED+    ESE    WS  SL+ +Q  Q + +D++MVHLL +AC  +GPLADALP++  EL+  G+LS+  LDLASK S  F++ FE AF 
Subjt:  QDSILTDHVAEDEDHGYESEP-SEWSFASLSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKKFETAFR

Query:  DQMNSTSFSQFWN-PSDFGGPTSSQLSSRYLSDFEELKSLG
          M STS  QFW  PSD   P +S  SSRYL+DFEELK LG
Subjt:  DQMNSTSFSQFWN-PSDFGGPTSSQLSSRYLSDFEELKSLG

Sequences

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CDS sequence

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ATGCCTATTGGATCCCTTTTCTACCGATTTGTCCATTTTTTCCATGTTATGGAAGGTGAAAGTCCCAAAAAAGGTGTAGTTTTTTGGGACAGTTTTGTGGAAGCCGAAGC
TCCATATCTATTTGGGACAGTTTTGTGGTTGGTTGGGTTTCAGTTCAAGATACGTTTTGCTTCAATTCTTTATATTAGAATCTCCAAGCTTCATTATCAGAATTTTGGTT
GGATCTATGAAGTCCTTATACCTGCACAAGATTCTATTCTCACAGACCATGTTGCTGAAGATGAAGACCATGGGTATGAAAGTGAGCCTTCAGAGTGGTCTTTTGCTTCC
TTAAGTAATGAACAAGAGTCCCAAACTACTGATAGGGATATAATGATGGTTCATCTGCTCCATCTTGCATGTGCCCCTAAAGGACCATTGGCTGATGCTCTGCCAAAATT
GGCATCTGAACTTTACAATTTTGGGGTCCTGTCAAAAGTTGCCCTGGATTTAGCTTCTAAACCATCTTCCATGTTTCATAAAAAATTTGAGACTGCTTTCCGGGACCAGA
TGAATTCTACTAGTTTCTCCCAGTTTTGGAATCCTTCTGATTTTGGCGGCCCAACATCTTCTCAACTGAGTTCTCGGTATCTTAGTGATTTTGAGGAGCTAAAGTCCCTT
GGTAATCCAATGCAGTTACCTGATTTAAGAAACTTCATTGATGATTGGGGGAAGGTGGATGTGGTTGGTCGAATCCTAAGAAGCACGGATACGGACATGAGACACGGATA
CGACACGACACGTACACGAGAACTAGACTCTTGGGTGGAGCTGACAAATAGGATTGACTCAATTCAGTTTGGAGAAGGGGCTGACAAGGTGGTACGGTACTACAGTCCCT
GTAATCCTTTGGCATCTTCTCCTCCATGTCTGCTTCTTGAAACTCATGGAAACAAGATCAACTGTGAACGCCTATATGGTTAA

mRNA sequence

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Protein sequence

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MPIGSLFYRFVHFFHVMEGESPKKGVVFWDSFVEAEAPYLFGTVLWLVGFQFKIRFASILYIRISKLHYQNFGWIYEVLIPAQDSILTDHVAEDEDHGYESEPSEWSFAS
LSNEQESQTTDRDIMMVHLLHLACAPKGPLADALPKLASELYNFGVLSKVALDLASKPSSMFHKKFETAFRDQMNSTSFSQFWNPSDFGGPTSSQLSSRYLSDFEELKSL
GNPMQLPDLRNFIDDWGKVDVVGRILRSTDTDMRHGYDTTRTRELDSWVELTNRIDSIQFGEGADKVVRYYSPCNPLASSPPCLLLETHGNKINCERLYG

Spg014485 (gene) of Sponge gourd (cylindrica) v1 genome