CuGenDBv2

Gene ID	Spg019250
Organism	Luffa cylindrica (Sponge gourd (cylindrica) v1)
Description	Separase
Genome location	scaffold1:46269365..46285090
RNA-Seq Expression	Spg019250
Synteny	Spg019250
Gene Ontology terms	GO:0006508 - proteolysis (biological process) GO:0005634 - nucleus (cellular component) GO:0004197 - cysteine-type endopeptidase activity (molecular function)
InterPro domains	IPR005314 - Peptidase C50, separase

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

XP_022149193.1 separase isoform X1 [Momordica charantia]

1.3e-101

47.17

Show/hide

Query:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR
        QELVEY EMS LYP FCQ LQMKILSTLLRDVY+TPD+ LE+ARVL+KKAR LRFCET+CLE+ I+CLS+AISTMNETS GTC+SGVLH HQLAVAYCLR
Subjt:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR

Query:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA
        ALCTHE VPNSKQ+LQDIDS LS+WLEI SLDSLP DQ+ ILSEYMLLLLCNTFDLLSIKGCMDY+HNIYSLMIRLFKWKNVQLEK LA+LWE RRM HA
Subjt:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA

Query:  ICIAPANEIVIAQLSEHLGTC-------MNC-------LLGF----------------------------------------------------------
        +C AP NE+ IAQLSEHLG          NC       L+GF                                                          
Subjt:  ICIAPANEIVIAQLSEHLGTC-------MNC-------LLGF----------------------------------------------------------

Query:  -------------------------------MFLWIL-------------------------------------------IVECILAGKNCI--------
                                       MF++ +                                           +  C L+  N +        
Subjt:  -------------------------------MFLWIL-------------------------------------------IVECILAGKNCI--------

Query:  --------IGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPK------
                IGN               C   L           GKVYRKKQL SLA+KELEGAKQILTD+ITS LKC+LVLEVIVDQHLGDLF        
Subjt:  --------IGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPK------

Query:  -RIENEMELKEKKKEKMQRAKIKWKSWNDN
          I  E  +  +K  K+   K+    W D+
Subjt:  -RIENEMELKEKKKEKMQRAKIKWKSWNDN

XP_022149194.1 separase isoform X2 [Momordica charantia]

1.3e-101

47.17

Show/hide

Query:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR
        QELVEY EMS LYP FCQ LQMKILSTLLRDVY+TPD+ LE+ARVL+KKAR LRFCET+CLE+ I+CLS+AISTMNETS GTC+SGVLH HQLAVAYCLR
Subjt:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR

Query:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA
        ALCTHE VPNSKQ+LQDIDS LS+WLEI SLDSLP DQ+ ILSEYMLLLLCNTFDLLSIKGCMDY+HNIYSLMIRLFKWKNVQLEK LA+LWE RRM HA
Subjt:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA

Query:  ICIAPANEIVIAQLSEHLGTC-------MNC-------LLGF----------------------------------------------------------
        +C AP NE+ IAQLSEHLG          NC       L+GF                                                          
Subjt:  ICIAPANEIVIAQLSEHLGTC-------MNC-------LLGF----------------------------------------------------------

Query:  -------------------------------MFLWIL-------------------------------------------IVECILAGKNCI--------
                                       MF++ +                                           +  C L+  N +        
Subjt:  -------------------------------MFLWIL-------------------------------------------IVECILAGKNCI--------

Query:  --------IGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPK------
                IGN               C   L           GKVYRKKQL SLA+KELEGAKQILTD+ITS LKC+LVLEVIVDQHLGDLF        
Subjt:  --------IGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPK------

Query:  -RIENEMELKEKKKEKMQRAKIKWKSWNDN
          I  E  +  +K  K+   K+    W D+
Subjt:  -RIENEMELKEKKKEKMQRAKIKWKSWNDN

XP_022149195.1 separase isoform X3 [Momordica charantia]

1.3e-101

47.17

Show/hide

Query:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR
        QELVEY EMS LYP FCQ LQMKILSTLLRDVY+TPD+ LE+ARVL+KKAR LRFCET+CLE+ I+CLS+AISTMNETS GTC+SGVLH HQLAVAYCLR
Subjt:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR

Query:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA
        ALCTHE VPNSKQ+LQDIDS LS+WLEI SLDSLP DQ+ ILSEYMLLLLCNTFDLLSIKGCMDY+HNIYSLMIRLFKWKNVQLEK LA+LWE RRM HA
Subjt:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA

Query:  ICIAPANEIVIAQLSEHLGTC-------MNC-------LLGF----------------------------------------------------------
        +C AP NE+ IAQLSEHLG          NC       L+GF                                                          
Subjt:  ICIAPANEIVIAQLSEHLGTC-------MNC-------LLGF----------------------------------------------------------

Query:  -------------------------------MFLWIL-------------------------------------------IVECILAGKNCI--------
                                       MF++ +                                           +  C L+  N +        
Subjt:  -------------------------------MFLWIL-------------------------------------------IVECILAGKNCI--------

Query:  --------IGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPK------
                IGN               C   L           GKVYRKKQL SLA+KELEGAKQILTD+ITS LKC+LVLEVIVDQHLGDLF        
Subjt:  --------IGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPK------

Query:  -RIENEMELKEKKKEKMQRAKIKWKSWNDN
          I  E  +  +K  K+   K+    W D+
Subjt:  -RIENEMELKEKKKEKMQRAKIKWKSWNDN

XP_022149196.1 separase isoform X4 [Momordica charantia]

1.3e-101

47.17

Show/hide

Query:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR
        QELVEY EMS LYP FCQ LQMKILSTLLRDVY+TPD+ LE+ARVL+KKAR LRFCET+CLE+ I+CLS+AISTMNETS GTC+SGVLH HQLAVAYCLR
Subjt:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR

Query:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA
        ALCTHE VPNSKQ+LQDIDS LS+WLEI SLDSLP DQ+ ILSEYMLLLLCNTFDLLSIKGCMDY+HNIYSLMIRLFKWKNVQLEK LA+LWE RRM HA
Subjt:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA

Query:  ICIAPANEIVIAQLSEHLGTC-------MNC-------LLGF----------------------------------------------------------
        +C AP NE+ IAQLSEHLG          NC       L+GF                                                          
Subjt:  ICIAPANEIVIAQLSEHLGTC-------MNC-------LLGF----------------------------------------------------------

Query:  -------------------------------MFLWIL-------------------------------------------IVECILAGKNCI--------
                                       MF++ +                                           +  C L+  N +        
Subjt:  -------------------------------MFLWIL-------------------------------------------IVECILAGKNCI--------

Query:  --------IGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPK------
                IGN               C   L           GKVYRKKQL SLA+KELEGAKQILTD+ITS LKC+LVLEVIVDQHLGDLF        
Subjt:  --------IGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPK------

Query:  -RIENEMELKEKKKEKMQRAKIKWKSWNDN
          I  E  +  +K  K+   K+    W D+
Subjt:  -RIENEMELKEKKKEKMQRAKIKWKSWNDN

XP_023533736.1 separase isoform X1 [Cucurbita pepo subsp. pepo]

6.4e-101

46.79

Show/hide

Query:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR
        QELVEY EMSGLYPEFCQSLQMKILS LL D Y+TPD+RLEKARVL+KKARVLR CET+CL+ CI+CLSEAISTMNE SGG+ + GVLHSHQLAVAYCLR
Subjt:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR

Query:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA
        A CTHETVPNSKQ+ QDIDS LS+WLEISSL++LP DQ+LILSEYMLLLLCN FDLLSIKGC+DYY NIYSLMIRLFKWKNV LEK +A LWE RRMSHA
Subjt:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA

Query:  ICIAPANEIVIAQLSEHLG----------TCMNCLLG--------FMFLWI-------------------------------------------------
        +CIAPANE+VIAQLSEHLG           C+  L G        F FL                                                   
Subjt:  ICIAPANEIVIAQLSEHLG----------TCMNCLLG--------FMFLWI-------------------------------------------------

Query:  ---------LIVECILAGKNC-------------------------------------------------------------------------------
                  + E +L  K                                                                                 
Subjt:  ---------LIVECILAGKNC-------------------------------------------------------------------------------

Query:  -------IIGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPKRIEN--
               IIGN               C   L           GKVYRKKQL SLA+KELEGAKQILTDNITS LKC+LVLEVIVDQ+LGDLF     N  
Subjt:  -------IIGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPKRIEN--

Query:  -----EMELKEKKKEKMQRAKIKWKSWNDN
             E+ +  ++  K+   K+    W ++
Subjt:  -----EMELKEKKKEKMQRAKIKWKSWNDN

TrEMBL top hits

e value

%identity

Alignment

A0A6J1D524 Separase

6.2e-102

47.17

Show/hide

Query:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR
        QELVEY EMS LYP FCQ LQMKILSTLLRDVY+TPD+ LE+ARVL+KKAR LRFCET+CLE+ I+CLS+AISTMNETS GTC+SGVLH HQLAVAYCLR
Subjt:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR

Query:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA
        ALCTHE VPNSKQ+LQDIDS LS+WLEI SLDSLP DQ+ ILSEYMLLLLCNTFDLLSIKGCMDY+HNIYSLMIRLFKWKNVQLEK LA+LWE RRM HA
Subjt:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA

Query:  ICIAPANEIVIAQLSEHLGTC-------MNC-------LLGF----------------------------------------------------------
        +C AP NE+ IAQLSEHLG          NC       L+GF                                                          
Subjt:  ICIAPANEIVIAQLSEHLGTC-------MNC-------LLGF----------------------------------------------------------

Query:  -------------------------------MFLWIL-------------------------------------------IVECILAGKNCI--------
                                       MF++ +                                           +  C L+  N +        
Subjt:  -------------------------------MFLWIL-------------------------------------------IVECILAGKNCI--------

Query:  --------IGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPK------
                IGN               C   L           GKVYRKKQL SLA+KELEGAKQILTD+ITS LKC+LVLEVIVDQHLGDLF        
Subjt:  --------IGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPK------

Query:  -RIENEMELKEKKKEKMQRAKIKWKSWNDN
          I  E  +  +K  K+   K+    W D+
Subjt:  -RIENEMELKEKKKEKMQRAKIKWKSWNDN

A0A6J1D658 Separase

6.2e-102

47.17

Show/hide

Query:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR
        QELVEY EMS LYP FCQ LQMKILSTLLRDVY+TPD+ LE+ARVL+KKAR LRFCET+CLE+ I+CLS+AISTMNETS GTC+SGVLH HQLAVAYCLR
Subjt:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR

Query:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA
        ALCTHE VPNSKQ+LQDIDS LS+WLEI SLDSLP DQ+ ILSEYMLLLLCNTFDLLSIKGCMDY+HNIYSLMIRLFKWKNVQLEK LA+LWE RRM HA
Subjt:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA

Query:  ICIAPANEIVIAQLSEHLGTC-------MNC-------LLGF----------------------------------------------------------
        +C AP NE+ IAQLSEHLG          NC       L+GF                                                          
Subjt:  ICIAPANEIVIAQLSEHLGTC-------MNC-------LLGF----------------------------------------------------------

Query:  -------------------------------MFLWIL-------------------------------------------IVECILAGKNCI--------
                                       MF++ +                                           +  C L+  N +        
Subjt:  -------------------------------MFLWIL-------------------------------------------IVECILAGKNCI--------

Query:  --------IGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPK------
                IGN               C   L           GKVYRKKQL SLA+KELEGAKQILTD+ITS LKC+LVLEVIVDQHLGDLF        
Subjt:  --------IGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPK------

Query:  -RIENEMELKEKKKEKMQRAKIKWKSWNDN
          I  E  +  +K  K+   K+    W D+
Subjt:  -RIENEMELKEKKKEKMQRAKIKWKSWNDN

A0A6J1D6B5 Separase

6.2e-102

47.17

Show/hide

Query:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR
        QELVEY EMS LYP FCQ LQMKILSTLLRDVY+TPD+ LE+ARVL+KKAR LRFCET+CLE+ I+CLS+AISTMNETS GTC+SGVLH HQLAVAYCLR
Subjt:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR

Query:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA
        ALCTHE VPNSKQ+LQDIDS LS+WLEI SLDSLP DQ+ ILSEYMLLLLCNTFDLLSIKGCMDY+HNIYSLMIRLFKWKNVQLEK LA+LWE RRM HA
Subjt:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA

Query:  ICIAPANEIVIAQLSEHLGTC-------MNC-------LLGF----------------------------------------------------------
        +C AP NE+ IAQLSEHLG          NC       L+GF                                                          
Subjt:  ICIAPANEIVIAQLSEHLGTC-------MNC-------LLGF----------------------------------------------------------

Query:  -------------------------------MFLWIL-------------------------------------------IVECILAGKNCI--------
                                       MF++ +                                           +  C L+  N +        
Subjt:  -------------------------------MFLWIL-------------------------------------------IVECILAGKNCI--------

Query:  --------IGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPK------
                IGN               C   L           GKVYRKKQL SLA+KELEGAKQILTD+ITS LKC+LVLEVIVDQHLGDLF        
Subjt:  --------IGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPK------

Query:  -RIENEMELKEKKKEKMQRAKIKWKSWNDN
          I  E  +  +K  K+   K+    W D+
Subjt:  -RIENEMELKEKKKEKMQRAKIKWKSWNDN

A0A6J1D7N2 Separase

6.2e-102

47.17

Show/hide

Query:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR
        QELVEY EMS LYP FCQ LQMKILSTLLRDVY+TPD+ LE+ARVL+KKAR LRFCET+CLE+ I+CLS+AISTMNETS GTC+SGVLH HQLAVAYCLR
Subjt:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR

Query:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA
        ALCTHE VPNSKQ+LQDIDS LS+WLEI SLDSLP DQ+ ILSEYMLLLLCNTFDLLSIKGCMDY+HNIYSLMIRLFKWKNVQLEK LA+LWE RRM HA
Subjt:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA

Query:  ICIAPANEIVIAQLSEHLGTC-------MNC-------LLGF----------------------------------------------------------
        +C AP NE+ IAQLSEHLG          NC       L+GF                                                          
Subjt:  ICIAPANEIVIAQLSEHLGTC-------MNC-------LLGF----------------------------------------------------------

Query:  -------------------------------MFLWIL-------------------------------------------IVECILAGKNCI--------
                                       MF++ +                                           +  C L+  N +        
Subjt:  -------------------------------MFLWIL-------------------------------------------IVECILAGKNCI--------

Query:  --------IGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPK------
                IGN               C   L           GKVYRKKQL SLA+KELEGAKQILTD+ITS LKC+LVLEVIVDQHLGDLF        
Subjt:  --------IGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPK------

Query:  -RIENEMELKEKKKEKMQRAKIKWKSWNDN
          I  E  +  +K  K+   K+    W D+
Subjt:  -RIENEMELKEKKKEKMQRAKIKWKSWNDN

A0A6J1IQP1 Separase

5.3e-101

46.79

Show/hide

Query:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR
        QELVEY EMSGLYPEFCQSLQMKILS LL D Y+TPD+RLEKARVL+KKARVLR CET+CL+ CI+CLSEAISTMNE SGG  + GVLHSHQLAVAYCLR
Subjt:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR

Query:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA
        A CTHETVPNSKQ+ QDIDS LS+WLEISSL++LP DQ+LILSEYMLLLLCN FDLLSIKGC+DYY NIYSLMIRLFKWKNV LEK +A LWE RRMSHA
Subjt:  ALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRRMSHA

Query:  ICIAPANEIVIAQLSEHLG----------TCMNCLLG--------FMFLWI-------------------------------------------------
        +CIAP NE+VIAQLSEHLG           C+  L G        F FL                                                   
Subjt:  ICIAPANEIVIAQLSEHLG----------TCMNCLLG--------FMFLWI-------------------------------------------------

Query:  ---------LIVECILAGKNC-------------------------------------------------------------------------------
                  + E +L  K                                                                                 
Subjt:  ---------LIVECILAGKNC-------------------------------------------------------------------------------

Query:  -------IIGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPKRIEN--
               IIGN               C   L           GKVYRKKQL SLA+KELEGAKQILTDNITS LKCKLVLEVIVDQ+LGDLF     N  
Subjt:  -------IIGN---------------CCVLL----------AGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLVLEVIVDQHLGDLFPKRIEN--

Query:  -----EMELKEKKKEKMQRAKIKWKSWNDN
             E+ +  ++  K+   K+    W ++
Subjt:  -----EMELKEKKKEKMQRAKIKWKSWNDN

SwissProt top hits

e value

%identity

Alignment

Q5IBC5 Separase

1.6e-46

44.05

Show/hide

Query:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR
        QEL+ Y  +  L     Q  ++KI   LL+DVYVT D  +E+AR+L+ KAR+ R   T  +  CI  LSEAIS + E   G    G   SH L +AYCLR
Subjt:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR

Query:  ALCTHETVPNSKQILQDIDSTLSVWLEISSL----DSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRR
        A CT E  PNSK++ QDI ++L++WL I SL    DSLP       +E ++ LL N  DL+S+KGC + +H+IY L+ RLFKWKNV+LE  LA+LWE RR
Subjt:  ALCTHETVPNSKQILQDIDSTLSVWLEISSL----DSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRR

Query:  MSHAICIAPANEIVIAQLSEHLGTCMNCLLGFMFLWILIVECILAGKNCIIG
        +SHA+C +P ++  I  LSE+      C+  +M       +C+   K  +IG
Subjt:  MSHAICIAPANEIVIAQLSEHLGTCMNCLLGFMFLWILIVECILAGKNCIIG

Arabidopsis top hits

e value

%identity

Alignment

AT4G22970.1 homolog of separase

1.1e-47

44.05

Show/hide

Query:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR
        QEL+ Y  +  L     Q  ++KI   LL+DVYVT D  +E+AR+L+ KAR+ R   T  +  CI  LSEAIS + E   G    G   SH L +AYCLR
Subjt:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR

Query:  ALCTHETVPNSKQILQDIDSTLSVWLEISSL----DSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRR
        A CT E  PNSK++ QDI ++L++WL I SL    DSLP       +E ++ LL N  DL+S+KGC + +H+IY L+ RLFKWKNV+LE  LA+LWE RR
Subjt:  ALCTHETVPNSKQILQDIDSTLSVWLEISSL----DSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRR

Query:  MSHAICIAPANEIVIAQLSEHLGTCMNCLLGFMFLWILIVECILAGKNCIIG
        +SHA+C +P ++  I  LSE+      C+  +M       +C+   K  +IG
Subjt:  MSHAICIAPANEIVIAQLSEHLGTCMNCLLGFMFLWILIVECILAGKNCIIG

AT4G22970.2 homolog of separase

1.1e-47

44.05

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Query:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR
        QEL+ Y  +  L     Q  ++KI   LL+DVYVT D  +E+AR+L+ KAR+ R   T  +  CI  LSEAIS + E   G    G   SH L +AYCLR
Subjt:  QELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAISTMNETSGGTCNSGVLHSHQLAVAYCLR

Query:  ALCTHETVPNSKQILQDIDSTLSVWLEISSL----DSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRR
        A CT E  PNSK++ QDI ++L++WL I SL    DSLP       +E ++ LL N  DL+S+KGC + +H+IY L+ RLFKWKNV+LE  LA+LWE RR
Subjt:  ALCTHETVPNSKQILQDIDSTLSVWLEISSL----DSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNVQLEKRLAVLWEGRR

Query:  MSHAICIAPANEIVIAQLSEHLGTCMNCLLGFMFLWILIVECILAGKNCIIG
        +SHA+C +P ++  I  LSE+      C+  +M       +C+   K  +IG
Subjt:  MSHAICIAPANEIVIAQLSEHLGTCMNCLLGFMFLWILIVECILAGKNCIIG

Sequences

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CDS sequence

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ATGTCTCTGAGTTCCGCTGCGTGGTTTCAGTTTTTGCATGTTGCCAATAAGACTGACCTAGATAGCCTAGGTTGCTTAGTTGTGTGTGAGTTAGAGGTTGTTCCTCGTTC
TCCTCTCCATCACCAGTTAAATTCGTGCCCCAAGGTGAATTCCATTGTTCATCTTTCGATGCCTCAAGCGATGTTGACATTGGATGCATTGCAAGCTTTGATTGACAATG
CAATCCAAAGCAACTTGGAGCACCTTTTGCTCTTTCCTCGAGGTTATCTATTGCTCTGGGATTACCTTTCCTATTTTGATGCTTTGTCATCTGAATCTACCTATGATATT
CTCTGTTCCTTAGTTCGTTTCAAGGCTCTGTTGGTGTCGCCTAACTCCTTATTAGCTTTGCCGCTGCTTGGATTTCATGAATCAAGTCTCGAGGTTTTGGACTTGCTCGT
GACGATGCTCTTAATGGTGTTGGTTTCTTTAACCATGAGTCGGAGCATTTCCCTCACGCATGTCAGTTGTCGTCACGACGAAGTTACCTTGGTGAGTTGGCGCAGCGGAA
GCCGTTTCGAAGTAGTTGTTCCCTTCTTCAGTGATGCCTGTTTGAAGTTGGTGGTTGAAACTTACCAACTAGGTGGGTTAAAGTTGGTGAAGTTGCTGATGAAGCTTCCT
GCAGGATTGAGTCGTGCAAGATCGAAGTTTGGATTCAATCTTGTTAGGCCGTTTGAGTTCTCGGTGTGTGAAGTTAGGTTGCTCCTTGCCGTGAAACCCCTCCTGCCCGT
GTGTTCAACCGCCCAGCCCTCCCAGCCATCGCGTCGCCGCCTGACCGTCCAGCCGCCGTCGGAGGTTGCAGCCCGAGTCCCTGGTCGCGCCGCCCTTTGCGCGATTCCCT
TTCTCCTTTCATGGTCGTCGCGCAGCCCACCGTCTCTCCCTTTCTCTTCGTGCGTGGAAGCCCCAGCCGCCGCCGCTTTCCCTTGCAGCCGCGCCACCCTTCCTCTCTGT
TTCGTGGGTTTTAGATCCGTGGCTCCCTCTCCCTTTTTCCTTGCATCTTGCGCGGACAGCAGCTCGAAGCATCGTTTCCTCCGCGTTTCAGCCTTAGGAATTGTGGATCT
CGCGTGTCTAGCGATTCGGAGTCCCGTCGACCTCGTTTCAGTCAATTTCGCCTCTGTCCAGCAGCGTTTTTGGGTGTTTTCAGCACCGCTTGGCTATTCCGATAAGTTTA
AACGCTTACCCATGTTCACGGCTAAAAAGCCTTACCTGGAGCCGTTTGGCGAACACCCATTGCCCGTTTTCGAGGTGCTTGTGGAGCTTGGTGCAAGTGTTGCCTCGTTG
GTGCGGAGCATGACGCGGAAATCATGTAAATTGCGCAGCACATGGCTCGGAATTCATTGTGAGCTGCTTACCAGTACCACGGTTGTACTGATACCCCCTTCCCCACCTTC
CCCCAACATTTTAGATGTTGCAGGTATCGAGGATGATCTGGACCTTGGTGGCGAGGAGGAGAACTGCGAGGAAAAGTTTCTAGGGTGTTGGCCATTTTATGCCGTTATGC
TGCCGAAATTTTTGGTACATCCGGTTTATAGTGACTCAGTTCCAAAGTTAAGGGTTAAGAGTTGTAGTAGCGTTCCTAGGCTAAGGGTTGGAAAACCTGGGGCGTTACAA
TCCCAGAAAAACCACACCGACCTTGAATTGTTTATTGCAATCTTCTGGGATGTTGTCAAAGGCACAGATTGGTGCTCTCTTGGAGCAGGTACTGTATGTTACTTAAACAT
TGTACAGGAACTTGTTGAATATGCGGAAATGAGTGGTCTGTACCCAGAATTTTGTCAATCATTACAAATGAAGATCTTGAGTACTCTTCTAAGGGATGTGTATGTTACAC
CAGATAATAGACTAGAAAAAGCTAGAGTGTTGTTGAAAAAGGCAAGGGTATTGAGGTTTTGTGAAACTATATGTTTAGAAAATTGCATCCGGTGCTTATCAGAAGCAATA
TCTACAATGAATGAGACTTCTGGTGGAACTTGCAACTCTGGAGTTCTTCATTCTCATCAGTTAGCTGTTGCATATTGCTTACGTGCACTCTGTACTCATGAGACTGTACC
AAATTCAAAGCAAATCTTGCAAGATATAGATTCTACATTGAGCGTATGGTTGGAAATCTCAAGTCTGGATTCCTTGCCAGTTGATCAACAGTTGATACTGTCCGAGTATA
TGTTGCTGCTATTATGTAATACTTTTGATTTGTTATCAATCAAGGGTTGCATGGATTACTACCATAACATATACAGTCTCATGATTAGATTATTCAAATGGAAAAATGTT
CAATTGGAAAAGCGGTTGGCGGTTCTATGGGAAGGCAGAAGAATGAGTCATGCCATATGCATTGCCCCAGCAAATGAGATAGTTATAGCACAACTATCTGAGCATCTTGG
TACATGTATGAATTGTTTGCTTGGTTTCATGTTCCTGTGGATATTGATTGTTGAATGTATACTTGCTGGAAAGAACTGTATAATAGGTAATTGTTGTGTACTTCTGGCAG
GAAAAGTATATAGAAAGAAACAATTATCGAGTTTGGCACGAAAGGAACTTGAAGGAGCCAAACAGATATTAACGGATAACATTACATCTTATTTGAAGTGCAAATTGGTG
CTTGAAGTAATAGTTGATCAACATCTTGGGGACTTGTTTCCTAAGAGAATCGAAAATGAAATGGAGCTCAAAGAGAAAAAGAAGGAGAAGATGCAACGAGCCAAGATTAA
GTGGAAATCCTGGAATGACAATGGACTGGCAAAGTGCTTCTGCAAGCCCAAGTTTATTTACTGTAAAGAGGATTTTGCGGTTGGAAATTCCAGGGGAGACATATCTAAAT
TGGTGTTTTCTGGCCAGCCTCGAGGCGTGCGCTGTGACTTTTCAGATGGGTCTTTCATTCTTTTTTCTTCTCGGTTTCTCTCACCATCTCTCCCTCTCAATCATGGGCGG
GATTGCAGGCACGTTTATGTGGTTTTCCAACGTGTTTCAGGCACGGCAGTGGCTGGTATTCGTGATTTTTCAGTGGGTGTTCAATTTCAGCGCGACAGTGGTGTTTTTGG
AGTGCATTTGGGTGTTTTAGCGGAATATCGATTGTGGGATCCTCAAGTGATGGAATTTAAGAGAGAAAGTATGAAGAACAAGCTTGCAAGGTGGGTTTTGGTTAGTCTCG
AGCTAGCAAGGGGACCTAATGGACCTACAGATCATGGGCTCCAACGATCAAAGGATAACCCTAGACAAATAGGAGTTCATAGTAAGCTCAAGATTAAGATCGAGTTACCT
AAGTCATCGCACGAAATAATCAGTCTTAACAGTAAATGGCATTATAAAGTAAGAGTGACTTATTTCGCGGTCGAGTCTTGTGTAAACATCTTTTACACAGGATGCCCCTA
CTCGCATGTCTTTACATGA

mRNA sequence

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Protein sequence

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MSLSSAAWFQFLHVANKTDLDSLGCLVVCELEVVPRSPLHHQLNSCPKVNSIVHLSMPQAMLTLDALQALIDNAIQSNLEHLLLFPRGYLLLWDYLSYFDALSSESTYDI
LCSLVRFKALLVSPNSLLALPLLGFHESSLEVLDLLVTMLLMVLVSLTMSRSISLTHVSCRHDEVTLVSWRSGSRFEVVVPFFSDACLKLVVETYQLGGLKLVKLLMKLP
AGLSRARSKFGFNLVRPFEFSVCEVRLLLAVKPLLPVCSTAQPSQPSRRRLTVQPPSEVAARVPGRAALCAIPFLLSWSSRSPPSLPFSSCVEAPAAAAFPCSRATLPLC
FVGFRSVAPSPFFLASCADSSSKHRFLRVSALGIVDLACLAIRSPVDLVSVNFASVQQRFWVFSAPLGYSDKFKRLPMFTAKKPYLEPFGEHPLPVFEVLVELGASVASL
VRSMTRKSCKLRSTWLGIHCELLTSTTVVLIPPSPPSPNILDVAGIEDDLDLGGEEENCEEKFLGCWPFYAVMLPKFLVHPVYSDSVPKLRVKSCSSVPRLRVGKPGALQ
SQKNHTDLELFIAIFWDVVKGTDWCSLGAGTVCYLNIVQELVEYAEMSGLYPEFCQSLQMKILSTLLRDVYVTPDNRLEKARVLLKKARVLRFCETICLENCIRCLSEAI
STMNETSGGTCNSGVLHSHQLAVAYCLRALCTHETVPNSKQILQDIDSTLSVWLEISSLDSLPVDQQLILSEYMLLLLCNTFDLLSIKGCMDYYHNIYSLMIRLFKWKNV
QLEKRLAVLWEGRRMSHAICIAPANEIVIAQLSEHLGTCMNCLLGFMFLWILIVECILAGKNCIIGNCCVLLAGKVYRKKQLSSLARKELEGAKQILTDNITSYLKCKLV
LEVIVDQHLGDLFPKRIENEMELKEKKKEKMQRAKIKWKSWNDNGLAKCFCKPKFIYCKEDFAVGNSRGDISKLVFSGQPRGVRCDFSDGSFILFSSRFLSPSLPLNHGR
DCRHVYVVFQRVSGTAVAGIRDFSVGVQFQRDSGVFGVHLGVLAEYRLWDPQVMEFKRESMKNKLARWVLVSLELARGPNGPTDHGLQRSKDNPRQIGVHSKLKIKIELP
KSSHEIISLNSKWHYKVRVTYFAVESCVNIFYTGCPYSHVFT

Spg019250 (gene) of Sponge gourd (cylindrica) v1 genome