CuGenDBv2

Gene ID	Spg020977
Organism	Luffa cylindrica (Sponge gourd (cylindrica) v1)
Description	Mediator of RNA polymerase II transcription subunit
Genome location	scaffold9:1816732..1819833
RNA-Seq Expression	Spg020977
Synteny	Spg020977
Gene Ontology terms	GO:0006357 - regulation of transcription by RNA polymerase II (biological process) GO:0016592 - mediator complex (cellular component) GO:0003712 - transcription coregulator activity (molecular function)
InterPro domains	IPR009332 - Mediator of RNA polymerase II transcription subunit 22

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6598889.1 Cadmium/zinc-transporting ATPase HMA2, partial [Cucurbita argyrosperma subsp. sororia]

1.8e-24

86.49

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Query:  NKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
        + G  GG+GGG GPTAAAA AAAQKQK+LLQRV+ DIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
Subjt:  NKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM

XP_008459037.1 PREDICTED: mediator of RNA polymerase II transcription subunit 22a-like isoform X1 [Cucumis melo]

3.0e-27

84.71

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Query:  DSFTISICIIMNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
        DS  ISI IIMNKGI    GGG GPTAAAA AAAQKQK+LLQRV+ DIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRA+RM
Subjt:  DSFTISICIIMNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM

XP_022155216.1 mediator of RNA polymerase II transcription subunit 22b-like [Momordica charantia]

6.3e-25

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Query:  MNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
        MNKG+    GGGNGPTAAAA AAAQKQKVLLQRV+ DIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRA+RM
Subjt:  MNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM

XP_022929626.1 mediator of RNA polymerase II transcription subunit 22b-like [Cucurbita moschata]

2.4e-24

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Query:  MNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
        MNKGI    GGG GPTAAAA AAAQKQK+LLQRV+ DIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
Subjt:  MNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM

XP_023545554.1 mediator of RNA polymerase II transcription subunit 22b-like [Cucurbita pepo subsp. pepo]

2.4e-24

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Query:  MNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
        MNKGI    GGG GPTAAAA AAAQKQK+LLQRV+ DIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
Subjt:  MNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM

TrEMBL top hits

e value

%identity

Alignment

A0A1S3CAG5 mediator of RNA polymerase II transcription subunit 22a-like isoform X1

1.5e-27

84.71

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Query:  DSFTISICIIMNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
        DS  ISI IIMNKGI    GGG GPTAAAA AAAQKQK+LLQRV+ DIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRA+RM
Subjt:  DSFTISICIIMNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM

A0A5A7TMC4 Mediator of RNA polymerase II transcription subunit 22a-like isoform X1

1.5e-27

84.71

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Query:  DSFTISICIIMNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
        DS  ISI IIMNKGI    GGG GPTAAAA AAAQKQK+LLQRV+ DIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRA+RM
Subjt:  DSFTISICIIMNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM

A0A6J1DR20 mediator of RNA polymerase II transcription subunit 22b-like

3.0e-25

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Query:  MNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
        MNKG+    GGGNGPTAAAA AAAQKQKVLLQRV+ DIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRA+RM
Subjt:  MNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM

A0A6J1EN95 mediator of RNA polymerase II transcription subunit 22b-like

1.2e-24

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Query:  MNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
        MNKGI    GGG GPTAAAA AAAQKQK+LLQRV+ DIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
Subjt:  MNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM

A0A6J1K851 mediator of RNA polymerase II transcription subunit 22b-like isoform X1

1.2e-24

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Query:  MNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
        MNKGI    GGG GPTAAAA AAAQKQK+LLQRV+ DIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
Subjt:  MNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM

SwissProt top hits

e value

%identity

Alignment

Q8LCH5 Mediator of RNA polymerase II transcription subunit 22b

7.2e-24

75.32

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Query:  MNK--GIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
        MNK  G GGG GGG+GPTAAAA AA QKQK LLQRV+ DI ++VDNFT +VNVSRV+DPPV+NSQE++MMEMRASRM
Subjt:  MNK--GIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM

Q9SA42 Mediator of RNA polymerase II transcription subunit 22a

1.8e-22

71.05

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Query:  IMNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
        +MNK  GGG GGG+GPTAAAA AA QKQK LLQRVD DI ++VDNF  +VNV+RV+DPP++NSQE++MMEMRASR+
Subjt:  IMNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM

Arabidopsis top hits

e value

%identity

Alignment

AT1G07950.1 Surfeit locus protein 5 subunit 22 of Mediator complex

5.1e-25

75.32

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Query:  MNK--GIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
        MNK  G GGG GGG+GPTAAAA AA QKQK LLQRV+ DI ++VDNFT +VNVSRV+DPPV+NSQE++MMEMRASRM
Subjt:  MNK--GIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM

AT1G16430.1 Surfeit locus protein 5 subunit 22 of Mediator complex

1.3e-23

71.05

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Query:  IMNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM
        +MNK  GGG GGG+GPTAAAA AA QKQK LLQRVD DI ++VDNF  +VNV+RV+DPP++NSQE++MMEMRASR+
Subjt:  IMNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRNSQESFMMEMRASRM

Sequences

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CDS sequence

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ACTTCTTTTCTTCGTCTTCACAGTTCACACGGCTTCCTCCTCCGTTACAGCAGGCTTATTGCCGCCGCTGCCTCTCTCCCGTTCACTGCTGCCACCGCCGTCGTCTTCCC
TACGCTCGATTCATTTACCATTTCCATTTGTATCATTATGAACAAAGGCATTGGAGGAGGACTTGGCGGTGGGAATGGCCCCACGGCGGCGGCTGCCACAGCGGCTGCTC
AGAAACAGAAAGTACTTCTCCAGAGAGTGGATAACGATATAGCCAACATTGTAGACAATTTCACCCACCTTGTCAATGTCTCTAGGGTGAACGATCCACCTGTTAGAAAT
TCTCAGGAATCCTTCATGATGGAAATGCGGGCATCTAGAATGAATCTCGAGAAGCGGATGAGGGACTTCCTATGGGAAGGGAGTGGGGAGGGTAGAGGTTCTCACCTAGT
GAATTGGGGTATGCTGTCCTTCATTTCGCTTGGGTTTCGTCACGCTTTATCCGATAGGGAAACGATGGATGTCATGGCTCTTCTTTCTTTGGTTGAGGGATTTAAGTTCA
GAGAGGGGAGGAGAGATAACGTGGAGTTATCTGGATTATATGGAGTTGATCGAGGAGTTCCTCCTCCATCTGCCTTTCGTGAGAAGGGTAGATTTTTGTGGCAAGTTGGG
ATGTATGCTTTGTTATGGGCTAAGAAGCACGAACACTTTAGTTTGGCTAGCTTGTCCGTGTCCGACACGTGTCGGACACTTGGACACGTATCGGACACTTGTTAG

mRNA sequence

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Protein sequence

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TSFLRLHSSHGFLLRYSRLIAAAASLPFTAATAVVFPTLDSFTISICIIMNKGIGGGLGGGNGPTAAAATAAAQKQKVLLQRVDNDIANIVDNFTHLVNVSRVNDPPVRN
SQESFMMEMRASRMNLEKRMRDFLWEGSGEGRGSHLVNWGMLSFISLGFRHALSDRETMDVMALLSLVEGFKFREGRRDNVELSGLYGVDRGVPPPSAFREKGRFLWQVG
MYALLWAKKHEHFSLASLSVSDTCRTLGHVSDTC

Spg020977 (gene) of Sponge gourd (cylindrica) v1 genome