CuGenDBv2

Gene ID	Spg021748
Organism	Luffa cylindrica (Sponge gourd (cylindrica) v1)
Description	dCTP pyrophosphatase 1
Genome location	scaffold2:4680494..4683469
RNA-Seq Expression	Spg021748
Synteny	Spg021748
Gene Ontology terms	GO:0006253 - dCTP catabolic process (biological process) GO:0042262 - DNA protection (biological process) GO:0005829 - cytosol (cellular component) GO:0000287 - magnesium ion binding (molecular function) GO:0047840 - dCTP diphosphatase activity (molecular function)
InterPro domains	IPR025984 - dCTP pyrophosphatase 1

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6589527.1 dCTP pyrophosphatase 1, partial [Cucurbita argyrosperma subsp. sororia]

6.3e-57

93.02

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Query:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        ME+R SYEPEK AKDVSLQELRD LAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLD
Subjt:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVGVAAAFARALP
        LGHAALSK+VKNANKYPV   AAFARALP
Subjt:  LGHAALSKIVKNANKYPVGVAAAFARALP

XP_004138182.1 dCTP pyrophosphatase 1 [Cucumis sativus]

2.2e-57

93.02

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Query:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        ME+R SYEPEK AKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLD
Subjt:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVGVAAAFARALP
        LGHAALSK+VKNANKYPV   AAF RALP
Subjt:  LGHAALSKIVKNANKYPVGVAAAFARALP

XP_022921755.1 dCTP pyrophosphatase 1-like [Cucurbita moschata]

3.7e-57

93.02

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Query:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        ME+R SYEPEK AKDVSLQELRD LAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLD
Subjt:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVGVAAAFARALP
        LGHAALSK+VKNANKYPV   AAFARALP
Subjt:  LGHAALSKIVKNANKYPVGVAAAFARALP

XP_022933743.1 dCTP pyrophosphatase 1-like isoform X2 [Cucurbita moschata]

4.8e-57

93.02

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Query:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        MESR SYEPEK AKDVSL ELRDRLAEFA+VRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEE+SDVLLYLVRLADVCGLD
Subjt:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVGVAAAFARALP
        LGHAALSKIVKNANKYPV   AAFARALP
Subjt:  LGHAALSKIVKNANKYPVGVAAAFARALP

XP_038880679.1 dCTP pyrophosphatase 1-like [Benincasa hispida]

1.3e-57

93.8

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Query:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        MES  SYEPEK AKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLD
Subjt:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVGVAAAFARALP
        LGHAALSK+VKNANKYPV   AAFARALP
Subjt:  LGHAALSKIVKNANKYPVGVAAAFARALP

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LP76 dCTP pyrophosphatase 1

1.0e-57

93.02

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Query:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        ME+R SYEPEK AKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLD
Subjt:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVGVAAAFARALP
        LGHAALSK+VKNANKYPV   AAF RALP
Subjt:  LGHAALSKIVKNANKYPVGVAAAFARALP

A0A5A7UWT3 dCTP pyrophosphatase 1

1.2e-56

91.47

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Query:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        ME+R SYEPEK AKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLD
Subjt:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVGVAAAFARALP
        LGHAA+SK+VKNANKYPV   AA  RALP
Subjt:  LGHAALSKIVKNANKYPVGVAAAFARALP

A0A6J1E6P9 dCTP pyrophosphatase 1

1.8e-57

93.02

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Query:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        ME+R SYEPEK AKDVSLQELRD LAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLD
Subjt:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVGVAAAFARALP
        LGHAALSK+VKNANKYPV   AAFARALP
Subjt:  LGHAALSKIVKNANKYPVGVAAAFARALP

A0A6J1F5P6 dCTP pyrophosphatase 1

2.3e-57

93.02

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Query:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        MESR SYEPEK AKDVSL ELRDRLAEFA+VRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEE+SDVLLYLVRLADVCGLD
Subjt:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVGVAAAFARALP
        LGHAALSKIVKNANKYPV   AAFARALP
Subjt:  LGHAALSKIVKNANKYPVGVAAAFARALP

A0A6J1JJF8 dCTP pyrophosphatase 1

6.8e-57

92.25

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Query:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD
        ME+R SYEPEK AKDVSLQELRD L EFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLD
Subjt:  MESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLD

Query:  LGHAALSKIVKNANKYPVGVAAAFARALP
        LGHAALSK+VKNANKYPV   AAFARALP
Subjt:  LGHAALSKIVKNANKYPVGVAAAFARALP

SwissProt top hits

e value

%identity

Alignment

Q32KY6 dCTP pyrophosphatase 1

6.0e-26

49.19

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Query:  ESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL
        ES ++  P   + + +L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   WS  E+  L+EE+SD+L+YLV LA  C +DL
Subjt:  ESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKIVKNANKYPVGVAAAFA
          A L K+  N  +YPV ++   A
Subjt:  GHAALSKIVKNANKYPVGVAAAFA

Q91VC0 dCTP pyrophosphatase 1

7.8e-26

48.39

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Query:  ESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL
        E  ++  P   + + +L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   W   E+  L+EE+SDVL+YLV LA  C +DL
Subjt:  ESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKIVKNANKYPVGVAAAFA
          A +SK+  N  +YPV ++   A
Subjt:  GHAALSKIVKNANKYPVGVAAAFA

Q9H773 dCTP pyrophosphatase 1

2.3e-25

48.87

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Query:  TDNSEREMESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRL
        T   +     R S+ PE      +L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   WS  E+  L+EE+SDVL+YLV L
Subjt:  TDNSEREMESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRL

Query:  ADVCGLDLGHAALSKIVKNANKYPVGVAAAFAR
        A  C +DL  A LSK+  N  +YP  +A + +R
Subjt:  ADVCGLDLGHAALSKIVKNANKYPVGVAAAFAR

Q9QY93 dCTP pyrophosphatase 1

3.5e-26

48.39

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Query:  ESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL
        E  ++  P + + + +L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   W   E+  L+EE+SDVL+YLV LA  C +DL
Subjt:  ESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKIVKNANKYPVGVAAAFA
          A +SK+  N  +YPV ++   A
Subjt:  GHAALSKIVKNANKYPVGVAAAFA

Arabidopsis top hits

e value

%identity

Alignment

AT3G25400.1 CONTAINS InterPro DOMAIN/s: NTP Pyrophosphohydrolase MazG-related, RS21-C6 (InterPro:IPR011394), EAR (InterPro:IPR009039), NTP pyrophosphohydrolase MazG, putative catalytic core (InterPro:IPR004518); Has 1123 Blast hits to 1121 proteins in 452 species: Archae - 22; Bacteria - 753; Metazoa - 81; Fungi - 3; Plants - 83; Viruses - 0; Other Eukaryotes - 181 (source: NCBI BLink).

1.2e-37

71.84

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Query:  VSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGHAALSKIVKNANK
        VSLQ L  ++ +FA+ R WE+YHSPRNLLLA+VGEVGELSEIFQWKGEV RG P+W   EK HL EE+SDVLLYLVRL+D CG+DLG AAL KI  NA K
Subjt:  VSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGHAALSKIVKNANK

Query:  YPV
        YPV
Subjt:  YPV

Sequences

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CDS sequence

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ATGGCCCAACCGAACACAGATCACAACCACAAGCAGAGAAAAACAGATAACAGTGAGAGAGAAATGGAGAGTCGCAGTTCTTACGAACCTGAGAAAATCGCCAAAGACGT
CTCACTGCAAGAACTTCGAGACAGACTCGCAGAGTTCGCCCGAGTGCGAGGATGGGAGCAATACCACAGCCCTAGAAACCTGCTCCTAGCACTTGTCGGTGAGGTCGGAG
AGCTATCGGAGATATTCCAGTGGAAGGGGGAAGTGGAGAGGGGGCTGCCGAACTGGAGCGCGGCGGAGAAAGAGCATTTGGAAGAAGAAGTGTCCGATGTGTTGCTCTAT
TTGGTGCGTCTCGCCGACGTGTGTGGCCTTGATCTCGGCCATGCGGCGCTCTCGAAGATCGTAAAAAATGCGAACAAGTATCCCGTCGGCGTCGCCGCCGCTTTCGCTCG
CGCGCTGCCATGA

mRNA sequence

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Protein sequence

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MAQPNTDHNHKQRKTDNSEREMESRSSYEPEKIAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLY
LVRLADVCGLDLGHAALSKIVKNANKYPVGVAAAFARALP

Spg021748 (gene) of Sponge gourd (cylindrica) v1 genome