CuGenDBv2

Gene ID	Spg022265
Organism	Luffa cylindrica (Sponge gourd (cylindrica) v1)
Description	THO complex subunit 6
Genome location	scaffold2:8634480..8637849
RNA-Seq Expression	Spg022265
Synteny	Spg022265
Gene Ontology terms	GO:0009788 - negative regulation of abscisic acid-activated signaling pathway (biological process) GO:0010267 - production of ta-siRNAs involved in RNA interference (biological process) GO:0016567 - protein ubiquitination (biological process) GO:0000347 - THO complex (cellular component) GO:0080008 - Cul4-RING E3 ubiquitin ligase complex (cellular component) GO:0000166 - nucleotide binding (molecular function) GO:0003676 - nucleic acid binding (molecular function) GO:0004386 - helicase activity (molecular function) GO:0005515 - protein binding (molecular function)
InterPro domains	IPR001680 - WD40 repeat IPR015943 - WD40/YVTN repeat-like-containing domain superfamily IPR036322 - WD40-repeat-containing domain superfamily IPR042626 - THO complex subunit 6

Homology

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GenBank top hits

e value

%identity

Alignment

XP_038880257.1 THO complex subunit 6 isoform X1 [Benincasa hispida]

4.8e-72

77.27

Show/hide

Query:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII
        MLADATNWDE AYRESIYKERE+QTRTVFRTAWAPSLNGCPETIV ASSDGSIASYSIASCISKL                      HFGYG+T+     
Subjt:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII

Query:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK
           LAAEPHCFLQGHDGPAYDVKFYDNG++TLLLSCGDDGHIRGW WRECTDIEVP+YLQGSHIEPV+DLMNPQYK
Subjt:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK

XP_038880258.1 THO complex subunit 6 isoform X2 [Benincasa hispida]

4.8e-72

77.27

Show/hide

Query:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII
        MLADATNWDE AYRESIYKERE+QTRTVFRTAWAPSLNGCPETIV ASSDGSIASYSIASCISKL                      HFGYG+T+     
Subjt:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII

Query:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK
           LAAEPHCFLQGHDGPAYDVKFYDNG++TLLLSCGDDGHIRGW WRECTDIEVP+YLQGSHIEPV+DLMNPQYK
Subjt:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK

XP_038880260.1 THO complex subunit 6 isoform X3 [Benincasa hispida]

4.8e-72

77.27

Show/hide

Query:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII
        MLADATNWDE AYRESIYKERE+QTRTVFRTAWAPSLNGCPETIV ASSDGSIASYSIASCISKL                      HFGYG+T+     
Subjt:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII

Query:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK
           LAAEPHCFLQGHDGPAYDVKFYDNG++TLLLSCGDDGHIRGW WRECTDIEVP+YLQGSHIEPV+DLMNPQYK
Subjt:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK

XP_038880261.1 THO complex subunit 6 isoform X4 [Benincasa hispida]

4.8e-72

77.27

Show/hide

Query:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII
        MLADATNWDE AYRESIYKERE+QTRTVFRTAWAPSLNGCPETIV ASSDGSIASYSIASCISKL                      HFGYG+T+     
Subjt:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII

Query:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK
           LAAEPHCFLQGHDGPAYDVKFYDNG++TLLLSCGDDGHIRGW WRECTDIEVP+YLQGSHIEPV+DLMNPQYK
Subjt:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK

XP_038880263.1 THO complex subunit 6 isoform X5 [Benincasa hispida]

4.8e-72

77.27

Show/hide

Query:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII
        MLADATNWDE AYRESIYKERE+QTRTVFRTAWAPSLNGCPETIV ASSDGSIASYSIASCISKL                      HFGYG+T+     
Subjt:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII

Query:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK
           LAAEPHCFLQGHDGPAYDVKFYDNG++TLLLSCGDDGHIRGW WRECTDIEVP+YLQGSHIEPV+DLMNPQYK
Subjt:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK

TrEMBL top hits

e value

%identity

Alignment

A0A1S3BQ99 THO complex subunit 6

5.7e-71

75.57

Show/hide

Query:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII
        MLADATNWDE AYRESIYKERE+QTRTVFRTAWAPSLNGCPETIV ASSDGS+ASYSIASCISKL                       FGYG+TK     
Subjt:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII

Query:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK
           LAAEPHCFLQGHDGP YDVKFYDNGD+TLLLSCGDDGHIRGW WR+CTDIEVP+YLQGSHIEPV+DLMNPQ+K
Subjt:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK

A0A5A7UQQ6 THO complex subunit 6

5.7e-71

75.57

Show/hide

Query:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII
        MLADATNWDE AYRESIYKERE+QTRTVFRTAWAPSLNGCPETIV ASSDGS+ASYSIASCISKL                       FGYG+TK     
Subjt:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII

Query:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK
           LAAEPHCFLQGHDGP YDVKFYDNGD+TLLLSCGDDGHIRGW WR+CTDIEVP+YLQGSHIEPV+DLMNPQ+K
Subjt:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK

A0A6J1D376 THO complex subunit 6

1.4e-69

75.57

Show/hide

Query:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII
        M ADATNWDEDAYRESI+KEREVQTRTVFRTAWAPSLNG PETIVVASSDGSIASYSIASCISKL                      HFGY + K     
Subjt:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII

Query:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK
          FLAAEPHCFLQGHDGPAYDVKFYD+GD+TLLLSCGDDGHIRGW WRECTDIE+P+Y QGSHIEPV+DL NPQYK
Subjt:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK

A0A6J1F6F8 THO complex subunit 6

1.1e-69

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Query:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII
        ML DATNWDEDAYRES+YKEREVQTRTVFRTAWAPSL+GCPE+IVVASSDGSIASYSIASCISKL                      H GYG+TK     
Subjt:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII

Query:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK
           LAAEPHCFLQGHDGP YDVKF+D GD+TLLLSCGDDGHIRGW W ECTDIEVP+YLQGSHIEPV+DLMNPQYK
Subjt:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK

A0A6J1HSS1 THO complex subunit 6

5.3e-69

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Query:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII
        ML DATNWDEDAYRES+YKEREVQTRTVFRTAWAPSL+GCPE+IVVASSDGSIASYSIASCISKL                      H GYG+TK     
Subjt:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVII

Query:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK
           LAAEPHCFLQGHDGPAYDVKF+D GD+TLLLSCGDDGHIRGW W ECTDIEVP+YLQGSHIEPV+DLMN QYK
Subjt:  SYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK

SwissProt top hits

e value

%identity

Alignment

Q8L4M1 THO complex subunit 6

6.5e-40

46.89

Show/hide

Query:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLN-GCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVI
        M  DATNW+ED YRESI KERE++TRTVFRTAWAP      P+  VVASSDG++A +S+ S +S+                        FGY  +K Q +
Subjt:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLN-GCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVI

Query:  ISYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK
            + AEP   ++ H+GPAYDVKFY   +  LLLSCGDDG +RGW WRE  + +V L+L+ +H++P+++L+NPQ+K
Subjt:  ISYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK

Arabidopsis top hits

e value

%identity

Alignment

AT2G19430.1 DWD (DDB1-binding WD40 protein) hypersensitive to ABA 1

4.6e-41

46.89

Show/hide

Query:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLN-GCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVI
        M  DATNW+ED YRESI KERE++TRTVFRTAWAP      P+  VVASSDG++A +S+ S +S+                        FGY  +K Q +
Subjt:  MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLN-GCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVI

Query:  ISYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK
            + AEP   ++ H+GPAYDVKFY   +  LLLSCGDDG +RGW WRE  + +V L+L+ +H++P+++L+NPQ+K
Subjt:  ISYFLAAEPHCFLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK

Sequences

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CDS sequence

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ATGTTGGCGGACGCAACGAATTGGGACGAAGATGCCTACAGAGAGAGTATATACAAAGAGAGAGAGGTCCAAACTCGGACTGTGTTCAGAACTGCATGGGCGCCCTCTTT
GAATGGTTGCCCTGAGACCATCGTGGTCGCCTCCAGTGATGGATCCATTGCCTCTTATTCTATCGCTTCCTGCATCTCTAAGCTGTGCATAAATAGCAAACTGAGGACCT
TTGGAAGGGTGAAGAGAGAACGTAATGTGACCAATGGAAAGCATTTTGGCTATGGCGATACTAAAAGGCAAGTCATTATATCTTATTTCCTGGCAGCAGAGCCTCATTGC
TTCCTTCAAGGGCACGATGGGCCCGCATATGATGTCAAATTTTATGATAATGGTGACAGTACTTTATTACTGAGCTGTGGTGATGATGGTCACATTCGAGGATGGAGTTG
GAGAGAATGTACAGATATAGAGGTGCCTCTTTATTTGCAAGGTAGTCACATTGAGCCTGTAGTGGACCTGATGAATCCTCAATACAAGTAG

mRNA sequence

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Protein sequence

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MLADATNWDEDAYRESIYKEREVQTRTVFRTAWAPSLNGCPETIVVASSDGSIASYSIASCISKLCINSKLRTFGRVKRERNVTNGKHFGYGDTKRQVIISYFLAAEPHC
FLQGHDGPAYDVKFYDNGDSTLLLSCGDDGHIRGWSWRECTDIEVPLYLQGSHIEPVVDLMNPQYK

Spg022265 (gene) of Sponge gourd (cylindrica) v1 genome