CuGenDBv2

Gene ID	Spg027379
Organism	Luffa cylindrica (Sponge gourd (cylindrica) v1)
Description	AP-2 complex subunit alpha
Genome location	scaffold7:43967762..43972707
RNA-Seq Expression	Spg027379
Synteny	Spg027379
Gene Ontology terms	GO:0006886 - intracellular protein transport (biological process) GO:0016192 - vesicle-mediated transport (biological process) GO:0005886 - plasma membrane (cellular component) GO:0030117 - membrane coat (cellular component)
InterPro domains	IPR008152 - Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain IPR013041 - Clathrin adaptor, appendage, Ig-like subdomain superfamily

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6606016.1 AP-2 complex subunit alpha-2, partial [Cucurbita argyrosperma subsp. sororia]

3.8e-29

57.97

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Query:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL
        S  L+    + IGIKA+WRA LG+LVLFLGNKNTSPL S KA ILPPSNLK+ELSLVP TIPPRAQ                             VNVKL
Subjt:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL

Query:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI
         L  VFNKFLQPIS+S E+FFP  R LSG PLKL+EV+
Subjt:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI

KAG7035965.1 AP-2 complex subunit alpha-2 [Cucurbita argyrosperma subsp. argyrosperma]

3.8e-29

57.97

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Query:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL
        S  L+    + IGIKA+WRA LG+LVLFLGNKNTSPL S KA ILPPSNLK+ELSLVP TIPPRAQ                             VNVKL
Subjt:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL

Query:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI
         L  VFNKFLQPIS+S E+FFP  R LSG PLKL+EV+
Subjt:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI

XP_022140395.1 AP-2 complex subunit alpha-1-like [Momordica charantia]

1.7e-29

58.7

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Query:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL
        S  L+    + IGIKA+WRA +G+LVLFLGNKNTSPLAS KAIILPPSNLK+ELSLVP TIPPRAQ                             V+VKL
Subjt:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL

Query:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI
         L  VFNKFLQPISVS E+FFP  R LSG PLKL+EV+
Subjt:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI

XP_022958427.1 AP-2 complex subunit alpha-1-like [Cucurbita moschata]

3.8e-29

57.97

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Query:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL
        S  L+    + IGIKA+WRA LG+LVLFLGNKNTSPL S KA ILPPSNLK+ELSLVP TIPPRAQ                             VNVKL
Subjt:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL

Query:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI
         L  VFNKFLQPIS+S E+FFP  R LSG PLKL+EV+
Subjt:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI

XP_023533645.1 AP-2 complex subunit alpha-1-like [Cucurbita pepo subsp. pepo]

3.8e-29

57.97

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Query:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL
        S  L+    + IGIKA+WRA LG+LVLFLGNKNTSPL S KA ILPPSNLK+ELSLVP TIPPRAQ                             VNVKL
Subjt:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL

Query:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI
         L  VFNKFLQPIS+S E+FFP  R LSG PLKL+EV+
Subjt:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI

TrEMBL top hits

e value

%identity

Alignment

A0A5A7SSE0 AP-2 complex subunit alpha

6.9e-29

57.97

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Query:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL
        S  L+    + IGIKA+WRA LG+LVLFLGNKN SPL   KAIILPPSNLK+ELSLVP+TIPPRAQ                             VNVKL
Subjt:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL

Query:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI
         L  VFNKFLQPISVS E+FFP  R LSG PLKL+EV+
Subjt:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI

A0A6J1CEZ5 AP-2 complex subunit alpha

8.2e-30

58.7

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Query:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL
        S  L+    + IGIKA+WRA +G+LVLFLGNKNTSPLAS KAIILPPSNLK+ELSLVP TIPPRAQ                             V+VKL
Subjt:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL

Query:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI
         L  VFNKFLQPISVS E+FFP  R LSG PLKL+EV+
Subjt:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI

A0A6J1FXU6 AP-2 complex subunit alpha

6.9e-29

57.97

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Query:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL
        S  L+    + IGIKA+WRA LG+LVLFLGNK+ SPLA  KAIILPPSNLK+ELSLVP+TIPPRAQ                             VNVKL
Subjt:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL

Query:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI
         L  VFNKFLQPISVS E+FFP  R LSG PLKL+EV+
Subjt:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI

A0A6J1H1T0 AP-2 complex subunit alpha

1.8e-29

57.97

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Query:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL
        S  L+    + IGIKA+WRA LG+LVLFLGNKNTSPL S KA ILPPSNLK+ELSLVP TIPPRAQ                             VNVKL
Subjt:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL

Query:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI
         L  VFNKFLQPIS+S E+FFP  R LSG PLKL+EV+
Subjt:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI

A0A6J1JAJ1 AP-2 complex subunit alpha

6.9e-29

57.97

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Query:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL
        S  L+    + IGIKA+WRA LG+LVLFLGNK+ SPLA  KAIILPPSNLK+ELSLVP+TIPPRAQ                             VNVKL
Subjt:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL

Query:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI
         L  VFNKFLQPISVS E+FFP  R LSG PLKL+EV+
Subjt:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI

SwissProt top hits

e value

%identity

Alignment

Q6NPD7 Nudix hydrolase 10

7.9e-14

54.41

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Query:  IKGKNGVWLKLPIEFANLVEAVVK---------PKYLILVYWIPEGAHTLPINATHRVGIGAFVLNDN
        ++GK GVWL LP+   NLVE  VK         P YL+LVYWIPE   T+P+NA+HRV +GA VLN N
Subjt:  IKGKNGVWLKLPIEFANLVEAVVK---------PKYLILVYWIPEGAHTLPINATHRVGIGAFVLNDN

Q8LPK4 AP-2 complex subunit alpha-2

1.3e-24

45.65

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Query:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL
        S  L+    + IGIKA+WR   G+LVLF+GNKNTSPL S +A+ILPP++L+L+LS VP+TIPPRAQ                             V+ KL
Subjt:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL

Query:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI
         +    NKFLQP+ +++E+FFP  R +SG PLKL+EV+
Subjt:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI

Q8LPL6 AP-2 complex subunit alpha-1

1.3e-24

45.65

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Query:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL
        S  L+    + IGIKA+WR   G+LVLF+GNKNTSPL S +A+ILPP++L+L+LS VP+TIPPRAQ                             V+ KL
Subjt:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL

Query:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI
         +    NKFLQP+ +++E+FFP  R +SG PLKL+EV+
Subjt:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI

Q94B74 Nudix hydrolase 2

6.7e-13

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Query:  AIFSTYLLRRN-----IKGKNGVWLKLPIEFANLVEAVVK---------PKYLILVYWIPEGAHTLPINATHRVGIGAFVLNDN
        ++FST LLR +     ++GK GVW+KLP +   L E  VK           YL+LVYWIP+   TLP NA+HRVGIGAFV+N N
Subjt:  AIFSTYLLRRN-----IKGKNGVWLKLPIEFANLVEAVVK---------PKYLILVYWIPEGAHTLPINATHRVGIGAFVLNDN

Q9SJC6 Nudix hydrolase 5

1.9e-12

47.76

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Query:  KGKNGVWLKLPIEFANLVEAVVKP---------KYLILVYWIPEGAHTLPINATHRVGIGAFVLNDN
        +GK G+W+KLP E ++LV+  +K          +Y++L +W+PE   TLP NA+HR+GIGAFVLN N
Subjt:  KGKNGVWLKLPIEFANLVEAVVKP---------KYLILVYWIPEGAHTLPINATHRVGIGAFVLNDN

Arabidopsis top hits

e value

%identity

Alignment

AT4G25434.1 nudix hydrolase homolog 10

5.6e-15

54.41

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Query:  IKGKNGVWLKLPIEFANLVEAVVK---------PKYLILVYWIPEGAHTLPINATHRVGIGAFVLNDN
        ++GK GVWL LP+   NLVE  VK         P YL+LVYWIPE   T+P+NA+HRV +GA VLN N
Subjt:  IKGKNGVWLKLPIEFANLVEAVVK---------PKYLILVYWIPEGAHTLPINATHRVGIGAFVLNDN

AT5G22770.1 alpha-adaptin

9.2e-26

45.65

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Query:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL
        S  L+    + IGIKA+WR   G+LVLF+GNKNTSPL S +A+ILPP++L+L+LS VP+TIPPRAQ                             V+ KL
Subjt:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL

Query:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI
         +    NKFLQP+ +++E+FFP  R +SG PLKL+EV+
Subjt:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI

AT5G22770.2 alpha-adaptin

9.2e-26

45.65

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Query:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL
        S  L+    + IGIKA+WR   G+LVLF+GNKNTSPL S +A+ILPP++L+L+LS VP+TIPPRAQ                             V+ KL
Subjt:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL

Query:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI
         +    NKFLQP+ +++E+FFP  R +SG PLKL+EV+
Subjt:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI

AT5G22770.3 alpha-adaptin

9.2e-26

45.65

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Query:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL
        S  L+    + IGIKA+WR   G+LVLF+GNKNTSPL S +A+ILPP++L+L+LS VP+TIPPRAQ                             V+ KL
Subjt:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL

Query:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI
         +    NKFLQP+ +++E+FFP  R +SG PLKL+EV+
Subjt:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI

AT5G22780.1 Adaptor protein complex AP-2, alpha subunit

9.2e-26

45.65

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Query:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL
        S  L+    + IGIKA+WR   G+LVLF+GNKNTSPL S +A+ILPP++L+L+LS VP+TIPPRAQ                             V+ KL
Subjt:  SNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQ-----------------------------VNVKL

Query:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI
         +    NKFLQP+ +++E+FFP  R +SG PLKL+EV+
Subjt:  HLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVI

Sequences

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CDS sequence

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ATGCCCAGCACCGCCGCCGCCCTCCCATCTCGTCTCTCTGTCTCTCGTCGTCCAACACTGCACGTCGCCACTAGTCTTCCTTCCAACCATCACCGGCGAACGCAGCGACC
ACGAAAGCGCGGTAGTAGCAATTTCTTGTTTGCCTCTCACAGTCTTGCTATTGGCATTAAAGCAAAGTGGCGAGCCCAACTAGGACAACTTGTTCTTTTTCTTGGAAACA
AAAATACTTCTCCTCTTGCCTCTTTCAAGGCTATCATATTGCCTCCTTCAAATTTAAAGCTGGAGTTGTCATTAGTACCTAATACTATTCCTCCCCGTGCACAGGTAAAT
GTGAAGCTTCACCTTCTAGTTGTCTTCAATAAATTTCTTCAGCCTATATCTGTATCTACAGAGAAGTTTTTCCCTTTGCAGAGATGGCTCTCAGGGCTCCCATTGAAGCT
TCGAGAAGTGATTGGTACTGAAGCTAGATGGGCTATTTTTAGCACCTATCTTTTGAGGAGAAACATTAAGGGCAAGAACGGTGTTTGGCTGAAACTGCCCATTGAGTTTG
CTAATCTAGTTGAAGCTGTTGTTAAGCCAAAGTATTTGATACTTGTGTATTGGATACCTGAAGGTGCTCATACTCTTCCTATAAATGCTACCCATCGAGTTGGCATTGGT
GCCTTTGTCTTGAACGACAAC

mRNA sequence

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Protein sequence

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MPSTAAALPSRLSVSRRPTLHVATSLPSNHHRRTQRPRKRGSSNFLFASHSLAIGIKAKWRAQLGQLVLFLGNKNTSPLASFKAIILPPSNLKLELSLVPNTIPPRAQVN
VKLHLLVVFNKFLQPISVSTEKFFPLQRWLSGLPLKLREVIGTEARWAIFSTYLLRRNIKGKNGVWLKLPIEFANLVEAVVKPKYLILVYWIPEGAHTLPINATHRVGIG
AFVLNDN

Spg027379 (gene) of Sponge gourd (cylindrica) v1 genome