CuGenDBv2

Gene ID	Spg027903
Organism	Luffa cylindrica (Sponge gourd (cylindrica) v1)
Description	DNA excision repair protein ERCC-1
Genome location	scaffold2:38123030..38124556
RNA-Seq Expression	Spg027903
Synteny	Spg027903
Gene Ontology terms	GO:0000710 - meiotic mismatch repair (biological process) GO:0006296 - nucleotide-excision repair, DNA incision, 5'-to lesion (biological process) GO:0006312 - mitotic recombination (biological process) GO:0070914 - UV-damage excision repair (biological process) GO:0000110 - nucleotide-excision repair factor 1 complex (cellular component) GO:0070522 - ERCC4-ERCC1 complex (cellular component) GO:0003684 - damaged DNA binding (molecular function) GO:0003697 - single-stranded DNA binding (molecular function) GO:0004518 - nuclease activity (molecular function)
InterPro domains	NA

Homology

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GenBank top hits

e value

%identity

Alignment

XP_022159708.1 DNA excision repair protein ERCC-1 isoform X2 [Momordica charantia]

1.9e-37

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Query:  MEQGDEEDNLQQTAHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTSAT-----PT
        MEQ +EEDNLQQT HKK+KTIIKIPSYQEV+E SQPK QSFSQAF+FLKSSEFYSPPPNP SASSSQ LP S ITN R+NDQL+TS  STSA+     PT
Subjt:  MEQGDEEDNLQQTAHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTSAT-----PT

Query:  NSLSGSSSVTRNAILVSNRQ
        NSLSGSSS TRNAILVSNRQ
Subjt:  NSLSGSSSVTRNAILVSNRQ

XP_022961554.1 DNA excision repair protein ERCC-1 isoform X1 [Cucurbita moschata]

1.1e-37

82.05

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Query:  EQGDEEDNLQQTAHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTS---ATPTNSL
        +QGDEE+NLQQTAHKK KTIIKIPSYQEV++SSQPKSQSFSQAFAFLKS+EFYSPPP P  ASSSQSLP SDITN R+NDQLDT   STS   ATP N L
Subjt:  EQGDEEDNLQQTAHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTS---ATPTNSL

Query:  SGSSSVTRNAILVSNRQ
        S SSSVTRNAILVSNRQ
Subjt:  SGSSSVTRNAILVSNRQ

XP_022961555.1 DNA excision repair protein ERCC-1 isoform X2 [Cucurbita moschata]

1.1e-37

82.05

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Query:  EQGDEEDNLQQTAHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTS---ATPTNSL
        +QGDEE+NLQQTAHKK KTIIKIPSYQEV++SSQPKSQSFSQAFAFLKS+EFYSPPP P  ASSSQSLP SDITN R+NDQLDT   STS   ATP N L
Subjt:  EQGDEEDNLQQTAHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTS---ATPTNSL

Query:  SGSSSVTRNAILVSNRQ
        S SSSVTRNAILVSNRQ
Subjt:  SGSSSVTRNAILVSNRQ

XP_022968743.1 DNA excision repair protein ERCC-1 isoform X1 [Cucurbita maxima]

1.9e-37

83.19

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Query:  MEQGDEEDNLQQT-AHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTS---ATPTN
        MEQGDEE+NLQQT AHKK KTIIKI SYQEV++SSQPKSQSFSQAFAFLKS+EFYSPPP P  ASSSQSLP SDITN R+NDQLDTS  STS   ATP N
Subjt:  MEQGDEEDNLQQT-AHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTS---ATPTN

Query:  SLSGSSSVTRNAILVSNRQ
        SLS SSSVTRNAILVSNRQ
Subjt:  SLSGSSSVTRNAILVSNRQ

XP_022968744.1 DNA excision repair protein ERCC-1 isoform X2 [Cucurbita maxima]

1.9e-37

83.19

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Query:  MEQGDEEDNLQQT-AHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTS---ATPTN
        MEQGDEE+NLQQT AHKK KTIIKI SYQEV++SSQPKSQSFSQAFAFLKS+EFYSPPP P  ASSSQSLP SDITN R+NDQLDTS  STS   ATP N
Subjt:  MEQGDEEDNLQQT-AHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTS---ATPTN

Query:  SLSGSSSVTRNAILVSNRQ
        SLS SSSVTRNAILVSNRQ
Subjt:  SLSGSSSVTRNAILVSNRQ

TrEMBL top hits

e value

%identity

Alignment

A0A6J1E0J7 DNA excision repair protein ERCC-1 isoform X1

9.3e-38

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Query:  MEQGDEEDNLQQTAHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTSAT-----PT
        MEQ +EEDNLQQT HKK+KTIIKIPSYQEV+E SQPK QSFSQAF+FLKSSEFYSPPPNP SASSSQ LP S ITN R+NDQL+TS  STSA+     PT
Subjt:  MEQGDEEDNLQQTAHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTSAT-----PT

Query:  NSLSGSSSVTRNAILVSNRQ
        NSLSGSSS TRNAILVSNRQ
Subjt:  NSLSGSSSVTRNAILVSNRQ

A0A6J1HCJ5 DNA excision repair protein ERCC-1 isoform X2

5.4e-38

82.05

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Query:  EQGDEEDNLQQTAHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTS---ATPTNSL
        +QGDEE+NLQQTAHKK KTIIKIPSYQEV++SSQPKSQSFSQAFAFLKS+EFYSPPP P  ASSSQSLP SDITN R+NDQLDT   STS   ATP N L
Subjt:  EQGDEEDNLQQTAHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTS---ATPTNSL

Query:  SGSSSVTRNAILVSNRQ
        S SSSVTRNAILVSNRQ
Subjt:  SGSSSVTRNAILVSNRQ

A0A6J1HED7 DNA excision repair protein ERCC-1 isoform X1

5.4e-38

82.05

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Query:  EQGDEEDNLQQTAHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTS---ATPTNSL
        +QGDEE+NLQQTAHKK KTIIKIPSYQEV++SSQPKSQSFSQAFAFLKS+EFYSPPP P  ASSSQSLP SDITN R+NDQLDT   STS   ATP N L
Subjt:  EQGDEEDNLQQTAHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTS---ATPTNSL

Query:  SGSSSVTRNAILVSNRQ
        S SSSVTRNAILVSNRQ
Subjt:  SGSSSVTRNAILVSNRQ

A0A6J1HYZ8 DNA excision repair protein ERCC-1 isoform X1

9.3e-38

83.19

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Query:  MEQGDEEDNLQQT-AHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTS---ATPTN
        MEQGDEE+NLQQT AHKK KTIIKI SYQEV++SSQPKSQSFSQAFAFLKS+EFYSPPP P  ASSSQSLP SDITN R+NDQLDTS  STS   ATP N
Subjt:  MEQGDEEDNLQQT-AHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTS---ATPTN

Query:  SLSGSSSVTRNAILVSNRQ
        SLS SSSVTRNAILVSNRQ
Subjt:  SLSGSSSVTRNAILVSNRQ

A0A6J1I0J7 DNA excision repair protein ERCC-1 isoform X2

9.3e-38

83.19

Show/hide

Query:  MEQGDEEDNLQQT-AHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTS---ATPTN
        MEQGDEE+NLQQT AHKK KTIIKI SYQEV++SSQPKSQSFSQAFAFLKS+EFYSPPP P  ASSSQSLP SDITN R+NDQLDTS  STS   ATP N
Subjt:  MEQGDEEDNLQQT-AHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTS---ATPTN

Query:  SLSGSSSVTRNAILVSNRQ
        SLS SSSVTRNAILVSNRQ
Subjt:  SLSGSSSVTRNAILVSNRQ

SwissProt top hits

e value

%identity

Alignment

Q9MA98 DNA excision repair protein ERCC-1

7.6e-13

45.31

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Query:  EQGDEEDNLQQTAHKKAKT--IIKIPSYQEVVESSQPK---------SQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLP--ASDIT-NTRENDQLDTSP
        + G++  +L Q   +K KT  +I +PSYQEV+ESSQ K         SQSFSQAFAF+KSS+ YSPPP P+SA++S S P  AS +  ++ +  Q D + 
Subjt:  EQGDEEDNLQQTAHKKAKT--IIKIPSYQEVVESSQPK---------SQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLP--ASDIT-NTRENDQLDTSP

Query:  PSTSATPTNSLSGSSSVTRNAILVSNRQ
         S++   T S+  +++  RNAILVS+RQ
Subjt:  PSTSATPTNSLSGSSSVTRNAILVSNRQ

Arabidopsis top hits

e value

%identity

Alignment

AT3G05210.1 nucleotide repair protein, putative

5.4e-14

45.31

Show/hide

Query:  EQGDEEDNLQQTAHKKAKT--IIKIPSYQEVVESSQPK---------SQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLP--ASDIT-NTRENDQLDTSP
        + G++  +L Q   +K KT  +I +PSYQEV+ESSQ K         SQSFSQAFAF+KSS+ YSPPP P+SA++S S P  AS +  ++ +  Q D + 
Subjt:  EQGDEEDNLQQTAHKKAKT--IIKIPSYQEVVESSQPK---------SQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLP--ASDIT-NTRENDQLDTSP

Query:  PSTSATPTNSLSGSSSVTRNAILVSNRQ
         S++   T S+  +++  RNAILVS+RQ
Subjt:  PSTSATPTNSLSGSSSVTRNAILVSNRQ

Sequences

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CDS sequence

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ATGGAGCAAGGAGACGAAGAAGATAACTTACAGCAAACCGCTCACAAAAAGGCCAAGACCATCATCAAGATACCCTCTTATCAAGAAGTCGTCGAAAGCTCACAGCCAAA
ATCGCAATCCTTCTCCCAAGCCTTTGCGTTCCTCAAATCCTCTGAATTTTACTCTCCTCCTCCAAACCCAACATCAGCTTCCTCCTCTCAATCCTTGCCCGCTTCTGACA
TCACAAACACAAGAGAAAACGATCAATTAGATACTTCACCTCCTTCAACATCGGCCACTCCAACTAATAGCTTGTCGGGGTCGAGCTCTGTTACTCGCAATGCCATTCTT
GTGAGCAATAGACAGTTGATGATGAACCTCTTTTGCGCCAGTGGTGCTGATTATCTTAATGGAATGTTGATGGTCTTTGAAGAGATCTCTGGCCTAGCATTAACAGATCA
AAATCCTCAGGCTTAG

mRNA sequence

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Protein sequence

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MEQGDEEDNLQQTAHKKAKTIIKIPSYQEVVESSQPKSQSFSQAFAFLKSSEFYSPPPNPTSASSSQSLPASDITNTRENDQLDTSPPSTSATPTNSLSGSSSVTRNAIL
VSNRQLMMNLFCASGADYLNGMLMVFEEISGLALTDQNPQA

Spg027903 (gene) of Sponge gourd (cylindrica) v1 genome