| GenBank top hits | e value | %identity | Alignment |
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| KAG7015549.1 DNA topoisomerase 1 beta [Cucurbita argyrosperma subsp. argyrosperma] | 0.0e+00 | 91.35 | Show/hide |
Query: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSIQSPV
MAV+TFGKAPMF DDDDEDN+PIVFKRSSASRQNQL+SE KH+QSQRLN+LSGR GSD S NGQSSNAQKRMTSLPKTSPM+ EIGSQK+ SSIQ P+
Subjt: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSIQSPV
Query: VKSSGTTLKASGSVDSRPKHLVNAAVKEEK---LPTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSGG
VKS GTTLK S S+DSRPK L NAA+KEE PTQENSDSEDDKPLS RLKGN NH SKG PTV KNK+KKSS DSDDE+PLSSKFQMKSASGV GG
Subjt: VKSSGTTLKASGSVDSRPKHLVNAAVKEEK---LPTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSGG
Query: KQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNKS
KQ GFDEKKPL SKVHQNGSTSRDKLQKP AVVSSKRPLPNADS SS Q S KKPKLSDSSTPLS+ VSLKAKQEV DDDD IPISQRM KMS +VNKS
Subjt: KQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNKS
Query: SSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLK
S SK+TVSKV SSSIKKT KKSKKPVKKSKYVKSTKLLPS+GDGQKKWTTLVHNGVIFPPPYQTHGVK+L+KGKPVDLTPEQEEVATMFAVMKDTDYM K
Subjt: SSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLK
Query: PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMT EEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
Subjt: PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
Query: KKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPT
KKRIRPSDITINIGKDAPIPECPIPG+RWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRN+YTKDFTSKDPT
Subjt: KKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPT
Query: RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHL
RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHL
Subjt: RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHL
Query: KDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDA
KDLMPGLTAKVFRT+NASITLDDMLNRGTKDG+V+EKIV YQHANKEVAIICNHQRTVSKSHGAQM+RLNEKISELRDI+KELKIDLDRAKKGKPPLK +
Subjt: KDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDA
Query: DGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
DGK+KRNLTPEALEKKISQTNAKIEKIERDM+TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDP+FRF
Subjt: DGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
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| XP_008449103.1 PREDICTED: DNA topoisomerase 1-like [Cucumis melo] | 0.0e+00 | 91.25 | Show/hide |
Query: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSS-IQSP
MAV+TFGKAPMF DDDDEDN+PIVFKRSSASRQNQLDSE KH+Q+QRLNKL GRQGSD+ STNGQSSN QKRMTSLPKTSPM+SEIGSQK+P SS IQ P
Subjt: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSS-IQSP
Query: VVKSSGTTLKASGSVDSRPKHLVNAAVKEEKL---PTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSG
+ KS G +LKAS S+DSRPK+LVNAAVKEE + P+QENSDSEDDKPLS RLKGN N +KGL T+PKNKVKKSSGDSDDE+PLSSKFQMK ASG G
Subjt: VVKSSGTTLKASGSVDSRPKHLVNAAVKEEKL---PTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSG
Query: GKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNK
KQ GFDEKKPLV KVHQNGSTSRDKLQKP AV+SSKRPLPN DS S QFSTKKPKLSDSS+PLSSK VSLKAKQEVDDDDDDIPISQR+KK +VNK
Subjt: GKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNK
Query: SSSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYML
SSSSK TVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTP+QEEVATMFAVMKDTDYML
Subjt: SSSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYML
Query: KPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGK
KPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQ EKEKKKQMT EEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGK
Subjt: KPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGK
Query: LKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDP
LK+RIRPSDITINIGK APIPECPIPGERWKEVRHDNTVTWLAFWNDPIN KEFKYVFLAASSSLKGQSDKEKYEKAR+LKDYIKNIRNAYTKDFTSKDP
Subjt: LKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDP
Query: TRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAH
TRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSI+YENTVEVELPVFKAITQFQSGKSG+DDLFDKLDT+KLNAH
Subjt: TRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAH
Query: LKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKD
LKDLMPGLTAKVFRT+NASITLDDMLNRGTKDG+V+EKIV YQHANKEVAIICNHQRTVSKSHGAQM+RLNEKISELRDI+KELKIDLDRAKKGKPPLK
Subjt: LKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKD
Query: ADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
+DGK+KRNLTPEALEKKISQTNAKIEKIERDM+TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
Subjt: ADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
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| XP_022932254.1 DNA topoisomerase 1 beta-like [Cucurbita moschata] | 0.0e+00 | 91.35 | Show/hide |
Query: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSIQSPV
MAV+TFGKAPMF DDDDEDN+PIVFKRSSASRQNQL+SE KH+QSQRLN+LSGR GSD S NGQSSNAQKRMTSLPKTSPM+ EIGSQK+ SSIQ P+
Subjt: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSIQSPV
Query: VKSSGTTLKASGSVDSRPKHLVNAAVKEEK---LPTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSGG
VKS GTTLK S S+DSRPK L NAAVKEE PTQENSDSEDDKPLS RLKGN NH SKG PTV KNK+KKSS DSDDE+PLSSKFQMKSASGV GG
Subjt: VKSSGTTLKASGSVDSRPKHLVNAAVKEEK---LPTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSGG
Query: KQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNKS
KQ GF EKKPL SKVHQNGSTSRDKLQKP AVVSSKRPLPNADS SS Q S+KKPKLSDSSTPLS+ VSLKAKQEV DDDD IPISQRM KMS +VNKS
Subjt: KQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNKS
Query: SSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLK
S SK+TVSKV SSSIKKT KKSKKPVKKSKYVKSTKLLPS+GDGQKKWTTLVHNGVIFPPPYQTHGVK+L+KGKPVDLT EQEEVATMFAVMKDTDYM K
Subjt: SSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLK
Query: PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMT EEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
Subjt: PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
Query: KKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPT
KKRIRPSDITINIGKDAPIPECPIPG+RWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRN+YTKDFTSKDPT
Subjt: KKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPT
Query: RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHL
RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHL
Subjt: RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHL
Query: KDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDA
KDLMPGLTAKVFRT+NASITLDDMLNRGTKDG+V+EKIV YQHANKEVAIICNHQRTVSKSHGAQM+RLNEKISELRDI+KELKIDLDRAKKGKPPLK +
Subjt: KDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDA
Query: DGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
DGK+KRNLTPEALEKKISQTNAKIEKIERDM+TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
Subjt: DGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
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| XP_023553297.1 DNA topoisomerase 1 beta-like [Cucurbita pepo subsp. pepo] | 0.0e+00 | 91.46 | Show/hide |
Query: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSIQSPV
MAV+TFGKAPMF DDDDEDN+PIVFKRSSASRQNQL+SE KH+QSQRLN+LSGR GSD S NGQSSNAQKRMTSLPKTSPM+ EIGSQK+ SSIQ P+
Subjt: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSIQSPV
Query: VKSSGTTLKASGSVDSRPKHLVNAAVKEEK---LPTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSGG
VKS GTTLK S S+DSRPK L NAAVKEE PTQ+NSDSEDDKPLS RLKGN NH SKG PTV KNK+KKSS DSDDE+PLSSKFQMKSASGV GG
Subjt: VKSSGTTLKASGSVDSRPKHLVNAAVKEEK---LPTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSGG
Query: KQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNKS
+Q GFDEKKPL SKVHQNGSTSRDKLQKP AVVSSKRPLPNADS SS Q S+KKPKLSDSSTPLS+ VSLKAKQEV DDDD IPISQRM KMS +VNKS
Subjt: KQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNKS
Query: SSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLK
S SK+TVSKV SSSIKKT KKSKKPVKKSKYVKSTKLLPS+GDGQKKWTTLVHNGVIFPPPYQTHGVK+L+KGKPVDLTPEQEEVATMFAVMKDTDYM K
Subjt: SSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLK
Query: PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMT EEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
Subjt: PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
Query: KKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPT
KKRIRPSDITINIGKDAPIPECPIPG+RWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRN+YTKDFTSKDPT
Subjt: KKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPT
Query: RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHL
RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHL
Subjt: RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHL
Query: KDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDA
KDLMPGLTAKVFRT+NASITLDDMLNRGTKDG+V+EKIV YQHANKEVAIICNHQRTVSKSHGAQM+RLNEKISELRDIVKELKIDLDRAKKGKPPLK +
Subjt: KDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDA
Query: DGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
DGK+KRNLTPEALEKKISQTNAKIEKIERDM+TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
Subjt: DGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
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| XP_038904656.1 DNA topoisomerase 1 alpha-like isoform X1 [Benincasa hispida] | 0.0e+00 | 91.91 | Show/hide |
Query: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSIQSPV
MAV+TFGKAPMFDDDDDEDN+PIVFKRSSASRQNQLDSE KH+QSQRLNKLSGRQGSD+ STNGQSSN QKRMTSLPKTSPM+SEIGSQK+ S I+ P
Subjt: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSIQSPV
Query: VKSSGTTLKASGSVDSRPKHLVNAAVKEEKLP---TQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSGG
VK GT+LK S S+DSR K LVN AVK+E + TQENSDSEDDKPLS RLKGN + +KGL PTVPKNKVKKSSGDSDDEIPLSSKFQMKS SGV G
Subjt: VKSSGTTLKASGSVDSRPKHLVNAAVKEEKLP---TQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSGG
Query: KQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNKS
KQ GFDEKKPLV +VHQNGSTSRDKLQKP AV+SSKRPLPNADS + Q STKKPKLSDSSTPLSSK VSLKAKQEVDD+DDDIPISQRMKKMS VNKS
Subjt: KQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNKS
Query: SSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLK
SSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVK+LYKGKPVDLTPEQEEVATMFAVMKDT+YMLK
Subjt: SSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLK
Query: PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQ EKEKKKQMT EEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
Subjt: PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
Query: KKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPT
K+RI PSDITINIGK APIPECPIPGERWKEVRHDNTVTWLAFWNDPIN KEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKD T
Subjt: KKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPT
Query: RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHL
RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVK VPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSG+DDLFDKLDTSKLNAHL
Subjt: RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHL
Query: KDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDA
KDLMPGLTAKVFRT+NASITLDDMLNRGTKDGDV EKI YQHANKEVAIICNHQRTVSKSHGAQM+RLNEKISELRDIVKELKIDLDRAKKGKPPLKDA
Subjt: KDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDA
Query: DGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
DGKRKRNLTPEALEKKISQTNAKIEKIERDM+TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
Subjt: DGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
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| TrEMBL top hits | e value | %identity | Alignment |
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| A0A0A0L2W2 DNA topoisomerase I | 0.0e+00 | 90.46 | Show/hide |
Query: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSS-IQSP
MAV+TFGKAPMF DDDDEDN+PIVFKR+SASRQNQLDSE KH+Q+QRL+KL GRQGSD+ STNGQSSN QKRMTSLPKTSPM+SEIGSQK+ SS I P
Subjt: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSS-IQSP
Query: VVKSSGTTLKASGSVDSRPKHLVNAAVKEEKL---PTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSG
+ KS GT+LKAS S+DSRPK LVNA VKEE + P+QENSDSEDDKPLS RLKGN N +KGL TVPKNKVKKS DSDDE+PLSSKFQMK ASGV G
Subjt: VVKSSGTTLKASGSVDSRPKHLVNAAVKEEKL---PTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSG
Query: GKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNK
KQ GFDEKKPLV KVHQNGSTSRDKLQKP AV+SSKRPLPN DS S QF TKKPKL+DSS+PL+SK VSLKAKQEVDDDDDDIPISQRMKK+S +VNK
Subjt: GKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNK
Query: SSSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYML
SSSSK T+SKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTP QEEVATMFAVMKDTDYML
Subjt: SSSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYML
Query: KPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGK
KPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQ EKEKKKQMT EEKKA+KEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGK
Subjt: KPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGK
Query: LKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDP
LK+RI PSDITINIGK APIPECPIPGERWKEVRHDNTVTWLAFWNDPIN KEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDP
Subjt: LKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDP
Query: TRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAH
TRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSI+YENTVEVELPVFKAITQFQSGKSG+DDLFDKLDTSKLNAH
Subjt: TRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAH
Query: LKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKD
LKDLMPGLTAKVFRT+NASITLDDMLNRGTK+G+V+EKIV YQHANKEVAIICNHQRTVSKSHGAQM+RLNEKISELRDI+KELKIDLDRAKKGKPPLK
Subjt: LKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKD
Query: ADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
+DGK+KRNLTPEALEKKISQTNAKIEKIERDM+TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
Subjt: ADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
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| A0A1S3BM72 DNA topoisomerase I | 0.0e+00 | 91.25 | Show/hide |
Query: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSS-IQSP
MAV+TFGKAPMF DDDDEDN+PIVFKRSSASRQNQLDSE KH+Q+QRLNKL GRQGSD+ STNGQSSN QKRMTSLPKTSPM+SEIGSQK+P SS IQ P
Subjt: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSS-IQSP
Query: VVKSSGTTLKASGSVDSRPKHLVNAAVKEEKL---PTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSG
+ KS G +LKAS S+DSRPK+LVNAAVKEE + P+QENSDSEDDKPLS RLKGN N +KGL T+PKNKVKKSSGDSDDE+PLSSKFQMK ASG G
Subjt: VVKSSGTTLKASGSVDSRPKHLVNAAVKEEKL---PTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSG
Query: GKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNK
KQ GFDEKKPLV KVHQNGSTSRDKLQKP AV+SSKRPLPN DS S QFSTKKPKLSDSS+PLSSK VSLKAKQEVDDDDDDIPISQR+KK +VNK
Subjt: GKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNK
Query: SSSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYML
SSSSK TVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTP+QEEVATMFAVMKDTDYML
Subjt: SSSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYML
Query: KPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGK
KPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQ EKEKKKQMT EEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGK
Subjt: KPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGK
Query: LKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDP
LK+RIRPSDITINIGK APIPECPIPGERWKEVRHDNTVTWLAFWNDPIN KEFKYVFLAASSSLKGQSDKEKYEKAR+LKDYIKNIRNAYTKDFTSKDP
Subjt: LKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDP
Query: TRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAH
TRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSI+YENTVEVELPVFKAITQFQSGKSG+DDLFDKLDT+KLNAH
Subjt: TRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAH
Query: LKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKD
LKDLMPGLTAKVFRT+NASITLDDMLNRGTKDG+V+EKIV YQHANKEVAIICNHQRTVSKSHGAQM+RLNEKISELRDI+KELKIDLDRAKKGKPPLK
Subjt: LKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKD
Query: ADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
+DGK+KRNLTPEALEKKISQTNAKIEKIERDM+TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
Subjt: ADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
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| A0A5A7VHI9 DNA topoisomerase I | 0.0e+00 | 89.44 | Show/hide |
Query: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSS-IQSP
MAV+TFGKAPMF DDDDEDN+PIVFKRSSASRQNQLDSE KH+Q+QRLNKL GRQGSD+ STNGQSSN QKRMTSLPKTSPM+SEIGSQK+P SS IQ P
Subjt: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSS-IQSP
Query: VVKSSGTTLKASGSVDSRPKHLVNAAVKEEKL---PTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSG
+ KS G +LKAS S+DSRPK+LVNAAVKEE + P+QENSDSEDDKPLS RLKGN N +KGL T+PKNKVKKSSGDSDDE+PLSSKFQMK ASG G
Subjt: VVKSSGTTLKASGSVDSRPKHLVNAAVKEEKL---PTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSG
Query: GKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNK
KQ GFDEKKPLV KVHQNGSTSRDKLQKP AV+SSKRPLPN DS S QFSTKKPKLSDSS+PLSSK VSLKAKQEVDDDDDDIPISQR+KK +VNK
Subjt: GKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNK
Query: SSSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYML
SSSSK TVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTP+QEEVATMFAVMKDTDYML
Subjt: SSSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYML
Query: KPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGK
KPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQ EKEKKKQMT EEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGK
Subjt: KPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGK
Query: LKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDP
LK+RIRPSDITINIGK APIPECPIPGERWKEVRHDNTVTWLAFWNDPIN KEFKYVFLAASSSLKGQSDKEKYEKAR+LKDYIKNIRNAYTKDFTSKDP
Subjt: LKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDP
Query: TRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAH
TRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSI+YENTVEVELPVFKAITQFQSGKSG+DDLFDKLDT+KLNAH
Subjt: TRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAH
Query: LKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKD
LKDLMPGLTAKVFRT+NASITLDDMLNRGTKDG+V+EKIV YQHANKEVAIICNHQRTVSKSHGAQM+RLNEKISELRDI+KELKIDLDRAKKGKPPLK
Subjt: LKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKD
Query: ADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK------------------IFNKSLLAKFAWA
+DGK+KRNLTPEALEKKISQTNAKIEKIERDM+TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK IFNKSLLAKFAWA
Subjt: ADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK------------------IFNKSLLAKFAWA
Query: MDVDPDFRF
MDVDPDFRF
Subjt: MDVDPDFRF
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| A0A6J1EWI0 DNA topoisomerase I | 0.0e+00 | 91.35 | Show/hide |
Query: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSIQSPV
MAV+TFGKAPMF DDDDEDN+PIVFKRSSASRQNQL+SE KH+QSQRLN+LSGR GSD S NGQSSNAQKRMTSLPKTSPM+ EIGSQK+ SSIQ P+
Subjt: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSIQSPV
Query: VKSSGTTLKASGSVDSRPKHLVNAAVKEEK---LPTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSGG
VKS GTTLK S S+DSRPK L NAAVKEE PTQENSDSEDDKPLS RLKGN NH SKG PTV KNK+KKSS DSDDE+PLSSKFQMKSASGV GG
Subjt: VKSSGTTLKASGSVDSRPKHLVNAAVKEEK---LPTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSGG
Query: KQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNKS
KQ GF EKKPL SKVHQNGSTSRDKLQKP AVVSSKRPLPNADS SS Q S+KKPKLSDSSTPLS+ VSLKAKQEV DDDD IPISQRM KMS +VNKS
Subjt: KQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNKS
Query: SSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLK
S SK+TVSKV SSSIKKT KKSKKPVKKSKYVKSTKLLPS+GDGQKKWTTLVHNGVIFPPPYQTHGVK+L+KGKPVDLT EQEEVATMFAVMKDTDYM K
Subjt: SSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLK
Query: PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMT EEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
Subjt: PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
Query: KKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPT
KKRIRPSDITINIGKDAPIPECPIPG+RWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRN+YTKDFTSKDPT
Subjt: KKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPT
Query: RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHL
RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHL
Subjt: RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHL
Query: KDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDA
KDLMPGLTAKVFRT+NASITLDDMLNRGTKDG+V+EKIV YQHANKEVAIICNHQRTVSKSHGAQM+RLNEKISELRDI+KELKIDLDRAKKGKPPLK +
Subjt: KDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDA
Query: DGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
DGK+KRNLTPEALEKKISQTNAKIEKIERDM+TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
Subjt: DGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
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| A0A6J1KZE0 DNA topoisomerase I | 0.0e+00 | 91.35 | Show/hide |
Query: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSIQSPV
MAV+TFGKA MF DDDDEDN+PIVFKRSSASRQNQL+SE KH+QSQRLN+LSGR GSD STNGQSSNAQKRMTSLPKTSPM+ EIGSQK+ SSIQ P+
Subjt: MAVQTFGKAPMFDDDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSIQSPV
Query: VKSSGTTLKASGSVDSRPKHLVNAAVKEEK---LPTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSGG
VKS GTTLK S S+DSRPK LVNAAVKEE P QENSDSEDDKPLS RLKGN NH SKG PTV KNK+KKSS DSDDE+PLSSKF+MKSASGV GG
Subjt: VKSSGTTLKASGSVDSRPKHLVNAAVKEEK---LPTQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSGG
Query: KQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNKS
KQ GFDEKKPL SKVHQNGSTS DKLQKP AVVSSKRPLPNADS SS Q S+KKPKLSDSSTPLS+ VSLKAKQEV DDDD IPISQRM KMS +VNKS
Subjt: KQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIPISQRMKKMSGSVNKS
Query: SSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLK
S SK+TVSKV SSSIKKT KKSKKPVKKSKYVKSTKLLPS+GDGQKKWTTLVHNGVIFPPPYQTHGVK+L+KGKPVDLTPEQEEVATMFAVMKDTDYM K
Subjt: SSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLK
Query: PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMT EEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
Subjt: PKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL
Query: KKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPT
KKRIRPSDITINIGKDAPIPECPIPG+RWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRN+YTKDFTSKDPT
Subjt: KKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPT
Query: RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHL
RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHL
Subjt: RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHL
Query: KDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDA
KDLMPGLTAKVFRT+NASITLDDMLNRGTKDG+V+EKIV YQHANKEVAIICNHQRTVSKSHGAQM+RLNEKISELRDI+KELKIDLDRAKKGKPPLK +
Subjt: KDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDA
Query: DGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
DGK+KRNLTPEALEKKISQTNAKIEKIERDM+TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
Subjt: DGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
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| SwissProt top hits | e value | %identity | Alignment |
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| P07799 DNA topoisomerase 1 | 1.2e-145 | 40.6 | Show/hide |
Query: TQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPL-----SSKFQMKSASGVSGGKQQGFDEKKPLVSKVHQNGSTSRDKLQKPA
+ E SDS ++ PLS L NK KS D DD IP+ SSK M ++S K G NG K K
Subjt: TQENSDSEDDKPLSCRLKGNFNHASKGLGPTVPKNKVKKSSGDSDDEIPL-----SSKFQMKSASGVSGGKQQGFDEKKPLVSKVHQNGSTSRDKLQKPA
Query: AVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKA-KQEVDDDDDDIPISQRMKKMSGSVNKSSSSKQTVSKVVSSSIKKTFKKSKKPVKKS
AVV + PS PK S SK + A K+E D DD +P+ + S + K + S++ ++ + +
Subjt: AVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKA-KQEVDDDDDDIPISQRMKKMSGSVNKSSSSKQTVSKVVSSSIKKTFKKSKKPVKKS
Query: KYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQ--THGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGK---NHVIQNL
K+ S + D +KWTTL HNGVIF PPY+ VK++Y G PV+L PE EEVA +A M +TD+ P F++NF+ D+ K+ + NH I+
Subjt: KYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQ--THGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGK---NHVIQNL
Query: DDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPI
CDFT ++ ++ ++E+KK M E+KKA+K++K ++EEKY W ILDG KEKVGNFR+EPPGLFRGRG HPK G LK+R+ P ITINIG+ P+PE P+
Subjt: DDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPI
Query: PGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDD
PG +W EV+HDNTVTWLA W++ IN KYVFLAA SSLKGQSD +KYEK+R LKDYI +IR Y KD S+ RQ A YLID ALRAGNEK +
Subjt: PGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDD
Query: DEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQF-QSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTFNASITLDD
DEADTVGCC+L+ E+V PP + F+FLGKDSI+Y N VEV+ VFK + F + K D +FD+L T+ LN +L LM GL+AKVFRT+NAS T+ +
Subjt: DEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQF-QSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTFNASITLDD
Query: MLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISEL---RDIVKELKIDLD-RAKKGKPPL----------------------
L + K+ +A+KI+ Y AN+ VAI+CNHQR+V+K+H QM R E+I L R ++++ ++L+ + K KP L
Subjt: MLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISEL---RDIVKELKIDLD-RAKKGKPPL----------------------
Query: -------------------------------------------KDADGKRKR----NLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYL
DA+ K K+ + E LEK++++ N +I + M K++ KT ALGTSKINY+
Subjt: -------------------------------------------KDADGKRKR----NLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYL
Query: DPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
DPR+T ++ KR +VPIEK+F+K++ KF WA D PD+++
Subjt: DPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
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| P30181 DNA topoisomerase 1 alpha | 4.8e-299 | 61.21 | Show/hide |
Query: MAVQTFGKAPMFDD--DDDEDNLPIVFKRSS--ASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSI
M +T K P+ D+ D +D+ P+ FKR++ AS NQ S ++ +++ K+S + S V S NG T KTS +KS + S S S
Subjt: MAVQTFGKAPMFDD--DDDEDNLPIVFKRSS--ASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSI
Query: QSPVVKSSGTTLKASGSVDSRPKHLVNAAVKEEKLPTQENSDSEDDKPLSCRLKGNFN-HASKGLGPTVPKNKVKKSSGD-------------SDDEIPL
+SP+ +T+K + K++ E+ DSEDD+PLS L GN +S+ + P+ KK++GD SDDE P+
Subjt: QSPVVKSSGTTLKASGSVDSRPKHLVNAAVKEEKLPTQENSDSEDDKPLSCRLKGNFN-HASKGLGPTVPKNKVKKSSGD-------------SDDEIPL
Query: SSKFQMKSASGVSGGKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVS---------------
SS F+ K SG+SGG Q DEKKPLV K+HQNGST ++++ P V KRPL + S+ Q S KK K+S S T + K S
Subjt: SSKFQMKSASGVSGGKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVS---------------
Query: -LKAKQ-------EVDDDDDDIPISQRMKKMSGSVNKSSSSKQTVS-------------KVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWT
+KAKQ DDDDDD+PIS+R K S + N SS+ + V VVS + K +KK K SKY S+K PS+GDGQKKWT
Subjt: -LKAKQ-------EVDDDDDDIPISQRMKKMSGSVNKSSSSKQTVS-------------KVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWT
Query: TLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAE
TLVHNGVIFPPPY+ HG+K+LYKGKPVDLT EQEEVATMFAVM++TDY KP+F+ENFWNDWR+LLGK HVIQ LDDCDFTPIY+W+ EKEKKKQM+ E
Subjt: TLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAE
Query: EKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPIN
EKKALKEEK+KQEEKYMWA++DGVKEK+GNFRVEPPGLFRGRGEHPKMGKLKKRI P +IT+NIGK APIPECPI GERWKEV+HDNTVTWLAFW DPIN
Subjt: EKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPIN
Query: PKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLE
PKEFKYVFL A SSLKG SDKEKYEKAR L D+I NIR YTK+FT+KD RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV+ +PPN ++
Subjt: PKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLE
Query: FNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVA
F+FLGKDSI+Y NTVEVE V+KAI QFQ+GKS +DDLFD+LDTSKLNAHLK+L+PGLTAKVFRT+NASITLD+ML++ TKDGDV +KIV+YQ ANKEVA
Subjt: FNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVA
Query: IICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINY
IICNHQRTVSK+HGAQ+ +L +I EL++++KELK +LDRAKKGKPPL+ +DGK+ R+L P A EKKI+Q +AKIEK+ERDM TKEDLKTVALGTSKINY
Subjt: IICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINY
Query: LDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
LDPRITVAWCKRHEVPIEKIF KSLL KFAWAMDV+P++RF
Subjt: LDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
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| P93119 DNA topoisomerase 1 | 1.7e-243 | 59.83 | Show/hide |
Query: VDSRPKHLVNAAVKEEKLPTQENSDSEDDKPLSCR-----LKGNFNHASKGLG------PTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSGGKQQGF
+ +++ +KEE + DS+DDKPLS + L GN +H G T PK ++ K +DE+ LSS+ Q+ +G S +
Subjt: VDSRPKHLVNAAVKEEKLPTQENSDSEDDKPLSCR-----LKGNFNHASKGLG------PTVPKNKVKKSSGDSDDEIPLSSKFQMKSASGVSGGKQQGF
Query: DEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPL--PNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLK-AKQEVDDDDDDIPISQRMKKMSGSVNKSSS
DE KPL S++ S+ +KRPL P PS +KK KLS+ S P + K LK A+QE DDD IS R KK + +K S
Subjt: DEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPL--PNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLK-AKQEVDDDDDDIPISQRMKKMSGSVNKSSS
Query: SKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLKPK
K+ VS+S+ K V SK +K +L +GQ LVHNGVIFPP Y+ HGVKMLY+ PVDLTPEQEEVATMFAVM +T+YM KPK
Subjt: SKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLKPK
Query: FKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLK-QEEKYMWAILDGV-KEKVGNFRVEPPGLFRGRGEHPKMGKL
F+ENF +DWRK+LG+ H+IQNL+DCDFTPIY+W+Q EKEKKKQM+ +EKKA+KE K + ++EKYMWA++DG+ +EKVGNFRV + + K ++
Subjt: FKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLK-QEEKYMWAILDGV-KEKVGNFRVEPPGLFRGRGEHPKMGKL
Query: KKRIRPS-DITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIR-NAYTKDFTSKD
KK + DITINIGKDAPIPE PIPGERWKE+RHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKG+ +EKYEK+R LKDYI+ IR AYTKDF SKD
Subjt: KKRIRPS-DITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIR-NAYTKDFTSKD
Query: PTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNA
+RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV+ PN+L+F+FLGKDSI+Y+N VEVE VF AI QF+SGK G DDLFD+LDTSKLNA
Subjt: PTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNA
Query: HLKDLMPGLTAKVFRTFNASITLDDM-----LNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKG
HLK+LMPGLTAKVFRT+NASITLD+M L+R TK GDVAEK+V+YQHANKEVAIICNHQRTVSKSH AQM RLNEKI EL+ ++KEL+ DL R KG
Subjt: HLKDLMPGLTAKVFRTFNASITLDDM-----LNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKG
Query: KPPLKDADGKRKRNLTPE----------------------ALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFN
KPPLK++DGK KRNL + ++ KKI+QTN KIEK+ERD +TKEDLKTVALGTSKINYLDPRITVAWCKRH+VPIEKIFN
Subjt: KPPLKDADGKRKRNLTPE----------------------ALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFN
Query: KSLLAKFAWAMDVDPDFRF
KSLLAKFAWAMDV FRF
Subjt: KSLLAKFAWAMDVDPDFRF
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| Q54RC3 DNA topoisomerase 1 | 5.9e-148 | 39 | Show/hide |
Query: KASGSVDSRPKHLVNAAVKEEKLPTQENSDSEDDKPLSCRLKGNFNHASKGLGPT-------------------VPKNKVKKSSGDSD------DEIPLS
K +G+V + P V ++ L E S + +K L N + K L PT +PK K SS DSD D S
Subjt: KASGSVDSRPKHLVNAAVKEEKLPTQENSDSEDDKPLSCRLKGNFNHASKGLGPT-------------------VPKNKVKKSSGDSD------DEIPLS
Query: SKFQMKSASGVSGGKQQGFDEKKPLVSKV--HQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDI
S S+S S +KKP +SK+ +G+ S+ P ++ S +P+ ++ DSS+ S DD D
Subjt: SKFQMKSASGVSGGKQQGFDEKKPLVSKV--HQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDI
Query: PISQRMKKMSGSVNKSSSSKQ-TVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLL---PSAGDGQ-----------------------------------
+ K S ++ K+ TV K +++ KKT K + VKK +TK + S DG+
Subjt: PISQRMKKMSGSVNKSSSSKQ-TVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLL---PSAGDGQ-----------------------------------
Query: ---------KKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLL--GKNHVIQNLDDCDFTPIYD
KWTTL+HNG +FPP Y HG+K +Y GK V LTP+QEEVAT +A +TD++ K FK+NF+ +++ LL + +++ +D CDF+ I+
Subjt: ---------KKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLL--GKNHVIQNLDDCDFTPIYD
Query: WYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGERWKEVRH
+T+KE++K + EEK A EK K +EK+ +A +DG KEKVGN+ +EPPGLF GRG+HPK G LK+RI PSD+T+NIG+ IP PIPGE+WKE+ H
Subjt: WYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGERWKEVRH
Query: DNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCT
+NTVTWLAFW + +N FKYV+LA SS +KGQ+D++K+E AR LK+ I +IR Y K F + +RQ+AVA YLID LALR GNEK +D+ADTVGCC+
Subjt: DNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCT
Query: LKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTFNASITLDDMLNR-GTKD-G
L+VE++K N + +FLGKDS++Y NTV++ +K + F GK +D LFD L ++LN HLK M GL+AKVFRT+NASITL L++ TK+
Subjt: LKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTFNASITLDDMLNR-GTKD-G
Query: DVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPP-------------------------LKDADGKR---
+ EKI+ Y N+EVAI+CNHQ+ K+ MS+++EKI ELRD+ DL R K GK P KD D ++
Subjt: DVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPP-------------------------LKDADGKR---
Query: -----------KRNLTPEA---LEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
K P+A +++KI++ +I+K E K++LKTVALGTSKINYLDPRITVAWCK+++VP++KIF KSL KF W+ DV D+ F
Subjt: -----------KRNLTPEA---LEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
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| Q9FJ79 DNA topoisomerase 1 beta | 1.1e-298 | 62.27 | Show/hide |
Query: DDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSIQSPVVKSSGTTLKASGS
+D+DED++P+VFKR+S ++ A + +N + + S + ST +SS + P TSP +S + S SS+ P + SS + +++
Subjt: DDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSIQSPVVKSSGTTLKASGS
Query: VDSRPKHLV-----NAAVKEEKLPTQENSDSEDDKPLSCRLKGNFNHASK-----GLGPT---VPKNKVKKSSGDS-------DDEIPLSSKFQMKSASG
R V N K + ++ DSEDDKPLS RLK + +K G G T V K+ ++ D+ P+SS Q K++ G
Subjt: VDSRPKHLV-----NAAVKEEKLPTQENSDSEDDKPLSCRLKGNFNHASK-----GLGPT---VPKNKVKKSSGDS-------DDEIPLSSKFQMKSASG
Query: VSGGKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPL--------------------SSKPV---SLKA
S K ++K+PLV+ + +NG + K + ++ +KRPL SS Q S K+PKLS+ + P+ +SKP+
Subjt: VSGGKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPL--------------------SSKPV---SLKA
Query: KQEVDDDDDDIPISQRMKKMSGSVNKSSSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKG
K++ D DD +PI+ RMK S S NKSSS+K + SK+++SS + +K K VK SKY KS+K LPS GDGQKKW TL HNGVIFPPPY+ HGVK+L++G
Subjt: KQEVDDDDDDIPISQRMKKMSGSVNKSSSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKG
Query: KPVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGV
KPVDLTPEQEEVATMFAVM++T+Y KPKF+ENFWNDWRKLLGKNH+I++LDDCDFTPIY+WY EKE KKQMTAEEK+ +KEEKLKQEEKYMWA+LDGV
Subjt: KPVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGV
Query: KEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKY
+E++GNFRVEPPGLFRGRGEHPKMGKLKKRIRP DITINIGK+APIPECPIPGERWKEV+HDNTVTWLAFW+DPINPKEFKYVFLAASSSLKGQSDKEKY
Subjt: KEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKY
Query: EKARMLKDYIKNIRNAYTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKA
EKAR L ++I +IR AYTKDF +KD T+RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV+ +PPN L+F+FLGKDSI+Y NTVEVE V+KA
Subjt: EKARMLKDYIKNIRNAYTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKA
Query: ITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKI
I QFQ+GKS +DDLFD+LDTSKLN HLK+LM GLTAKVFRT+NASITLD ML++ T+DGDV EK+V+YQ ANKEVAIICNHQRTVSKSHGAQ+ +L KI
Subjt: ITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKI
Query: SELRDIVKELKIDLDRAKKGKPPLKDADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS
ELR+ +KEL IDLDRAKKG+ PL +DGKRKRNLTPEALEKKI QT KIEK+ERDMQTKED+KTVALGTSKINY+DPRITVAWCKRH+VPIEKIFNKS
Subjt: SELRDIVKELKIDLDRAKKGKPPLKDADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS
Query: LLAKFAWAMDVDPDFRF
LLAKFAWAMDVDP+FRF
Subjt: LLAKFAWAMDVDPDFRF
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| Arabidopsis top hits | e value | %identity | Alignment |
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| AT4G26701.1 DNA binding;DNA topoisomerase type Is | 5.1e-30 | 89.71 | Show/hide |
Query: KIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
KIEK+ERDMQTKEDLKTVALGTSKINY+DPRITVAWCKRHE PIEKIFNKSLL KFAWAMDV+P F F
Subjt: KIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
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| AT5G55300.1 DNA topoisomerase I alpha | 3.4e-300 | 61.21 | Show/hide |
Query: MAVQTFGKAPMFDD--DDDEDNLPIVFKRSS--ASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSI
M +T K P+ D+ D +D+ P+ FKR++ AS NQ S ++ +++ K+S + S V S NG T KTS +KS + S S S
Subjt: MAVQTFGKAPMFDD--DDDEDNLPIVFKRSS--ASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSI
Query: QSPVVKSSGTTLKASGSVDSRPKHLVNAAVKEEKLPTQENSDSEDDKPLSCRLKGNFN-HASKGLGPTVPKNKVKKSSGD-------------SDDEIPL
+SP+ +T+K + K++ E+ DSEDD+PLS L GN +S+ + P+ KK++GD SDDE P+
Subjt: QSPVVKSSGTTLKASGSVDSRPKHLVNAAVKEEKLPTQENSDSEDDKPLSCRLKGNFN-HASKGLGPTVPKNKVKKSSGD-------------SDDEIPL
Query: SSKFQMKSASGVSGGKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVS---------------
SS F+ K SG+SGG Q DEKKPLV K+HQNGST ++++ P V KRPL + S+ Q S KK K+S S T + K S
Subjt: SSKFQMKSASGVSGGKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVS---------------
Query: -LKAKQ-------EVDDDDDDIPISQRMKKMSGSVNKSSSSKQTVS-------------KVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWT
+KAKQ DDDDDD+PIS+R K S + N SS+ + V VVS + K +KK K SKY S+K PS+GDGQKKWT
Subjt: -LKAKQ-------EVDDDDDDIPISQRMKKMSGSVNKSSSSKQTVS-------------KVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWT
Query: TLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAE
TLVHNGVIFPPPY+ HG+K+LYKGKPVDLT EQEEVATMFAVM++TDY KP+F+ENFWNDWR+LLGK HVIQ LDDCDFTPIY+W+ EKEKKKQM+ E
Subjt: TLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAE
Query: EKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPIN
EKKALKEEK+KQEEKYMWA++DGVKEK+GNFRVEPPGLFRGRGEHPKMGKLKKRI P +IT+NIGK APIPECPI GERWKEV+HDNTVTWLAFW DPIN
Subjt: EKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPIN
Query: PKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLE
PKEFKYVFL A SSLKG SDKEKYEKAR L D+I NIR YTK+FT+KD RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV+ +PPN ++
Subjt: PKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLE
Query: FNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVA
F+FLGKDSI+Y NTVEVE V+KAI QFQ+GKS +DDLFD+LDTSKLNAHLK+L+PGLTAKVFRT+NASITLD+ML++ TKDGDV +KIV+YQ ANKEVA
Subjt: FNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVA
Query: IICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINY
IICNHQRTVSK+HGAQ+ +L +I EL++++KELK +LDRAKKGKPPL+ +DGK+ R+L P A EKKI+Q +AKIEK+ERDM TKEDLKTVALGTSKINY
Subjt: IICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINY
Query: LDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
LDPRITVAWCKRHEVPIEKIF KSLL KFAWAMDV+P++RF
Subjt: LDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
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| AT5G55300.2 DNA topoisomerase I alpha | 1.1e-298 | 61.19 | Show/hide |
Query: MAVQTFGKAPMFDD--DDDEDNLPIVFKRSS--ASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSI
M +T K P+ D+ D +D+ P+ FKR++ AS NQ S ++ +++ K+S + S V S NG T KTS +KS + S S S
Subjt: MAVQTFGKAPMFDD--DDDEDNLPIVFKRSS--ASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSI
Query: QSPVVKSSGTTLKASGSVDSRPKHLVNAAVKEEKLPTQENSDSEDDKPLSCRLKGNFN-HASKGLGPTVPKNKVKKSSGD-------------SDDEIPL
+SP+ +T+K + K++ E+ DSEDD+PLS L GN +S+ + P+ KK++GD SDDE P+
Subjt: QSPVVKSSGTTLKASGSVDSRPKHLVNAAVKEEKLPTQENSDSEDDKPLSCRLKGNFN-HASKGLGPTVPKNKVKKSSGD-------------SDDEIPL
Query: SSKFQMKSASGVSGGKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVS---------------
SS F+ K SG+SGG Q DEKKPLV K+HQNGST ++++ P V KRPL + S+ Q S KK K+S S T + K S
Subjt: SSKFQMKSASGVSGGKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVS---------------
Query: -LKAKQ-------EVDDDDDDIPISQRMKKMSGSVNKSSSSKQTVS-------------KVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWT
+KAKQ DDDDDD+PIS+R K S + N SS+ + V VVS + K +KK K SKY S+K PS+GDGQKKWT
Subjt: -LKAKQ-------EVDDDDDDIPISQRMKKMSGSVNKSSSSKQTVS-------------KVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWT
Query: TLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAE
TLVHNGVIFPPPY+ HG+K+LYKGKPVDLT EQEEVATMFAVM++TDY KP+F+ENFWNDWR+LLGK HVIQ LDDCDFTPIY+W+ EKEKKKQM+ E
Subjt: TLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAE
Query: EKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPIN
EKKALKEEK+KQEEKYMWA++DGVKEK+GNFRVEPPGLFRGRGEHPKMGKLKKRI P +IT+NIGK APIPECPI GERWKEV+HDNTVTWLAFW DPIN
Subjt: EKKALKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPIN
Query: PKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLE
PKEFKYVFL A SSLKG SDKEKYEKAR L D+I NIR YTK+FT+KD RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV+ +PPN ++
Subjt: PKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLE
Query: FNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVA
F+FLGKDSI+Y NTVEVE V+KAI QFQ+GKS +DDLFD+LDTSKLNAHLK+L+PGLTAKVFRT+NASITLD+ML++ TKDGDV +KIV+YQ ANKEVA
Subjt: FNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVA
Query: IICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINY
IICNHQRTVSK+HGAQ+ +L +I EL++++KELK +LDRAKKGKPPL+ +DGK+ R+L P A EKKI+Q +AKIEK+ERDM TKEDLKTVALGTSKINY
Subjt: IICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINY
Query: LDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPD
LDPRITVAWCKRHEVPIEKIF KSLL KFAWAMDV+P+
Subjt: LDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPD
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| AT5G55300.3 DNA topoisomerase I alpha | 2.3e-118 | 76.01 | Show/hide |
Query: NEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTFNASI
++ DDDEADTVGCCTLKV NV+ +PPN ++F+FLGKDSI+Y NTVEVE V+KAI QFQ+GKS +DDLFD+LDTSKLNAHLK+L+PGLTAKVFRT+NASI
Subjt: NEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKAITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTFNASI
Query: TLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDADGKRKRNLTPEALEKKISQ
TLD+ML++ TKDGDV +KIV+YQ ANKEVAIICNHQRTVSK+HGAQ+ +L +I EL++++KELK +LDRAKKGKPPL+ +DGK+ R+L P A EKKI+Q
Subjt: TLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKISELRDIVKELKIDLDRAKKGKPPLKDADGKRKRNLTPEALEKKISQ
Query: TNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
+AKIEK+ERDM TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIF KSLL KFAWAMDV+P++RF
Subjt: TNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF
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| AT5G55300.3 DNA topoisomerase I alpha | 8.2e-20 | 35.29 | Show/hide |
Query: MAVQTFGKAPMFDD--DDDEDNLPIVFKRSS--ASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSI
M +T K P+ D+ D +D+ P+ FKR++ AS NQ S ++ +++ K+S + S V S NG T KTS +KS + S S S
Subjt: MAVQTFGKAPMFDD--DDDEDNLPIVFKRSS--ASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSI
Query: QSPVVKSSGTTLKASGSVDSRPKHLVNAAVKEEKLPTQENSDSEDDKPLSCRLKGNFN-HASKGLGPTVPKNKVKKSSGD-------------SDDEIPL
+SP+ +T+K + K++ E+ DSEDD+PLS L GN +S+ + P+ KK++GD SDDE P+
Subjt: QSPVVKSSGTTLKASGSVDSRPKHLVNAAVKEEKLPTQENSDSEDDKPLSCRLKGNFN-HASKGLGPTVPKNKVKKSSGD-------------SDDEIPL
Query: SSKFQMKSASGVSGGKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIP
SS F+ K SG+SGG Q DEKKPLV K+HQNGST ++++ P V KRPL + S+ Q S KK K+S S T + K S+ K+E+ DD +
Subjt: SSKFQMKSASGVSGGKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPLSSKPVSLKAKQEVDDDDDDIP
Query: ISQRMK
+S +MK
Subjt: ISQRMK
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| AT5G55310.1 DNA topoisomerase 1 beta | 7.6e-300 | 62.27 | Show/hide |
Query: DDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSIQSPVVKSSGTTLKASGS
+D+DED++P+VFKR+S ++ A + +N + + S + ST +SS + P TSP +S + S SS+ P + SS + +++
Subjt: DDDDEDNLPIVFKRSSASRQNQLDSEAKHTQSQRLNKLSGRQGSDVYSTNGQSSNAQKRMTSLPKTSPMKSEIGSQKSPNSSIQSPVVKSSGTTLKASGS
Query: VDSRPKHLV-----NAAVKEEKLPTQENSDSEDDKPLSCRLKGNFNHASK-----GLGPT---VPKNKVKKSSGDS-------DDEIPLSSKFQMKSASG
R V N K + ++ DSEDDKPLS RLK + +K G G T V K+ ++ D+ P+SS Q K++ G
Subjt: VDSRPKHLV-----NAAVKEEKLPTQENSDSEDDKPLSCRLKGNFNHASK-----GLGPT---VPKNKVKKSSGDS-------DDEIPLSSKFQMKSASG
Query: VSGGKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPL--------------------SSKPV---SLKA
S K ++K+PLV+ + +NG + K + ++ +KRPL SS Q S K+PKLS+ + P+ +SKP+
Subjt: VSGGKQQGFDEKKPLVSKVHQNGSTSRDKLQKPAAVVSSKRPLPNADSPSSPQFSTKKPKLSDSSTPL--------------------SSKPV---SLKA
Query: KQEVDDDDDDIPISQRMKKMSGSVNKSSSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKG
K++ D DD +PI+ RMK S S NKSSS+K + SK+++SS + +K K VK SKY KS+K LPS GDGQKKW TL HNGVIFPPPY+ HGVK+L++G
Subjt: KQEVDDDDDDIPISQRMKKMSGSVNKSSSSKQTVSKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKG
Query: KPVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGV
KPVDLTPEQEEVATMFAVM++T+Y KPKF+ENFWNDWRKLLGKNH+I++LDDCDFTPIY+WY EKE KKQMTAEEK+ +KEEKLKQEEKYMWA+LDGV
Subjt: KPVDLTPEQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQTEKEKKKQMTAEEKKALKEEKLKQEEKYMWAILDGV
Query: KEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKY
+E++GNFRVEPPGLFRGRGEHPKMGKLKKRIRP DITINIGK+APIPECPIPGERWKEV+HDNTVTWLAFW+DPINPKEFKYVFLAASSSLKGQSDKEKY
Subjt: KEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKY
Query: EKARMLKDYIKNIRNAYTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKA
EKAR L ++I +IR AYTKDF +KD T+RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV+ +PPN L+F+FLGKDSI+Y NTVEVE V+KA
Subjt: EKARMLKDYIKNIRNAYTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIKYENTVEVELPVFKA
Query: ITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKI
I QFQ+GKS +DDLFD+LDTSKLN HLK+LM GLTAKVFRT+NASITLD ML++ T+DGDV EK+V+YQ ANKEVAIICNHQRTVSKSHGAQ+ +L KI
Subjt: ITQFQSGKSGSDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTFNASITLDDMLNRGTKDGDVAEKIVIYQHANKEVAIICNHQRTVSKSHGAQMSRLNEKI
Query: SELRDIVKELKIDLDRAKKGKPPLKDADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS
ELR+ +KEL IDLDRAKKG+ PL +DGKRKRNLTPEALEKKI QT KIEK+ERDMQTKED+KTVALGTSKINY+DPRITVAWCKRH+VPIEKIFNKS
Subjt: SELRDIVKELKIDLDRAKKGKPPLKDADGKRKRNLTPEALEKKISQTNAKIEKIERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKS
Query: LLAKFAWAMDVDPDFRF
LLAKFAWAMDVDP+FRF
Subjt: LLAKFAWAMDVDPDFRF
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