CuGenDBv2

Gene ID	Spg031380
Organism	Luffa cylindrica (Sponge gourd (cylindrica) v1)
Description	DNA repair protein RAD50
Genome location	scaffold11:41777814..41780966
RNA-Seq Expression	Spg031380
Synteny	Spg031380
Gene Ontology terms	GO:0000722 - telomere maintenance via recombination (biological process) GO:0006302 - double-strand break repair (biological process) GO:0007004 - telomere maintenance via telomerase (biological process) GO:0032508 - DNA duplex unwinding (biological process) GO:0070192 - chromosome organization involved in meiotic cell cycle (biological process) GO:0090305 - nucleic acid phosphodiester bond hydrolysis (biological process) GO:0000794 - condensed nuclear chromosome (cellular component) GO:0030870 - Mre11 complex (cellular component) GO:0003691 - double-stranded telomeric DNA binding (molecular function) GO:0005524 - ATP binding (molecular function) GO:0016887 - ATPase activity (molecular function) GO:0043047 - single-stranded telomeric DNA binding (molecular function) GO:0046872 - metal ion binding (molecular function) GO:0051880 - G-quadruplex DNA binding (molecular function)
InterPro domains	IPR013134 - RAD50, zinc hook

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0049132.1 DNA repair protein RAD50 [Cucumis melo var. makuwa]

8.9e-34

60.99

Show/hide

Query:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M
        ADGMRQMFDPFERVARAHHVCP CERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSA SHFQQLDKLRMVFEEY    +    + ++E+  L   +
Subjt:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M

Query:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI
              LD+V+ V       +D     +Q   T+ + + +I
Subjt:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI

TYK17429.1 DNA repair protein RAD50 [Cucumis melo var. makuwa]

8.9e-34

60.99

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Query:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M
        ADGMRQMFDPFERVARAHHVCP CERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSA SHFQQLDKLRMVFEEY    +    + ++E+  L   +
Subjt:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M

Query:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI
              LD+V+ V       +D     +Q   T+ + + +I
Subjt:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI

XP_004133980.1 DNA repair protein RAD50 isoform X1 [Cucumis sativus]

2.0e-33

60.28

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Query:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M
        ADGMRQMFDPFERVARAHHVCP CERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSS+ SHFQQLDKLRMVFEEY    +    + ++E+  L   +
Subjt:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M

Query:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI
              LD+V+ V       +D     +Q   T+ + + +I
Subjt:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI

XP_008438322.1 PREDICTED: DNA repair protein RAD50 [Cucumis melo]

8.9e-34

60.99

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Query:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M
        ADGMRQMFDPFERVARAHHVCP CERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSA SHFQQLDKLRMVFEEY    +    + ++E+  L   +
Subjt:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M

Query:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI
              LD+V+ V       +D     +Q   T+ + + +I
Subjt:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI

XP_038891799.1 DNA repair protein RAD50 isoform X1 [Benincasa hispida]

2.0e-33

60.28

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Query:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M
        ADGMRQMFDPFERVARAHHVCP CERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESS+A SHFQQLDKLRMVFEEY    +    + ++E+  L   +
Subjt:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M

Query:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI
              LD+V+ V       +D     +Q   T+ + + +I
Subjt:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI

TrEMBL top hits

e value

%identity

Alignment

A0A0A0L416 Zinc-hook domain-containing protein

9.6e-34

60.28

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Query:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M
        ADGMRQMFDPFERVARAHHVCP CERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSS+ SHFQQLDKLRMVFEEY    +    + ++E+  L   +
Subjt:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M

Query:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI
              LD+V+ V       +D     +Q   T+ + + +I
Subjt:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI

A0A1S3AWR7 DNA repair protein RAD50

4.3e-34

60.99

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Query:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M
        ADGMRQMFDPFERVARAHHVCP CERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSA SHFQQLDKLRMVFEEY    +    + ++E+  L   +
Subjt:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M

Query:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI
              LD+V+ V       +D     +Q   T+ + + +I
Subjt:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI

A0A5A7U014 DNA repair protein RAD50

4.3e-34

60.99

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Query:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M
        ADGMRQMFDPFERVARAHHVCP CERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSA SHFQQLDKLRMVFEEY    +    + ++E+  L   +
Subjt:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M

Query:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI
              LD+V+ V       +D     +Q   T+ + + +I
Subjt:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI

A0A5D3D3I4 DNA repair protein RAD50

4.3e-34

60.99

Show/hide

Query:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M
        ADGMRQMFDPFERVARAHHVCP CERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSA SHFQQLDKLRMVFEEY    +    + ++E+  L   +
Subjt:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M

Query:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI
              LD+V+ V       +D     +Q   T+ + + +I
Subjt:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI

A0A6J1IVK4 DNA repair protein RAD50

3.7e-33

60.28

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Query:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M
        ADGMRQMFDPFERVARAHHVCP CERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSA SHFQ LDKLRMVFEEY    +      ++E+  L   +
Subjt:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIPAL---M

Query:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI
              LD+V+ V       +D     +Q   T+ + + +I
Subjt:  GVSKTILDNVIFV------HQDETNGPLQDPSTSKKKFDDI

SwissProt top hits

e value

%identity

Alignment

P70388 DNA repair protein RAD50

1.4e-10

51.72

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Query:  KVCLSYRCADMDREIPALMGVSKTILDNVIFVHQDETNGPLQDPSTSKKKFDDICSVT
        KV LS +CA++DRE+ + +GVSK++L+NVIF HQ+++N PL +    K+KFD+I S T
Subjt:  KVCLSYRCADMDREIPALMGVSKTILDNVIFVHQDETNGPLQDPSTSKKKFDDICSVT

Q54CS9 DNA repair protein RAD50

1.3e-11

43.82

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Query:  VESSSAVSHFQQLDKLRMVF--EEYKVCLSYRCADMDREIPALMGVSKTILDNVIFVHQDETNGPLQDPSTSKKKFDDICS-VTSTSAL
        ++ S+    ++Q+D     +  +  KV  S+RC+DMD+EIP LMGV+K IL +VIF HQ+++N PL + +  K KFD+I S V  T AL
Subjt:  VESSSAVSHFQQLDKLRMVF--EEYKVCLSYRCADMDREIPALMGVSKTILDNVIFVHQDETNGPLQDPSTSKKKFDDICS-VTSTSAL

Q92878 DNA repair protein RAD50

2.5e-10

51.72

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Query:  KVCLSYRCADMDREIPALMGVSKTILDNVIFVHQDETNGPLQDPSTSKKKFDDICSVT
        KV LS +CA++DRE+ + +GVSK +L+NVIF HQ+++N PL +    K+KFD+I S T
Subjt:  KVCLSYRCADMDREIPALMGVSKTILDNVIFVHQDETNGPLQDPSTSKKKFDDICSVT

Q9JIL8 DNA repair protein RAD50

1.4e-10

51.72

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Query:  KVCLSYRCADMDREIPALMGVSKTILDNVIFVHQDETNGPLQDPSTSKKKFDDICSVT
        KV LS +CA++DRE+ + +GVSK++L+NVIF HQ+++N PL +    K+KFD+I S T
Subjt:  KVCLSYRCADMDREIPALMGVSKTILDNVIFVHQDETNGPLQDPSTSKKKFDDICSVT

Q9SL02 DNA repair protein RAD50

3.9e-24

71.79

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Query:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEY
        A+GMRQMF+PFE+ AR  H CP CER FTA+EE  F+KKQRVKA+S+ EH+K LAVESS+A S FQQLDKLR VFEEY
Subjt:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEY

Arabidopsis top hits

e value

%identity

Alignment

AT2G31970.1 DNA repair-recombination protein (RAD50)

2.8e-25

71.79

Show/hide

Query:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEY
        A+GMRQMF+PFE+ AR  H CP CER FTA+EE  F+KKQRVKA+S+ EH+K LAVESS+A S FQQLDKLR VFEEY
Subjt:  ADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEY

Sequences

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CDS sequence

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ATGATTAACAAGGTTTTTGGTGCATTATCTACAGTAAGTACAATATTTGCAGATGGTATGCGTCAAATGTTTGATCCATTTGAAAGGGTTGCCCGTGCTCATCATGTTTG
CCCTGGTTGTGAGCGCCCCTTTACAGCAGAAGAAGAAGATGAATTTGTTAAAAAGCAAAGAGTGAAGGCTGCAAGTTCTGCTGAGCATATGAAAGTGCTTGCAGTGGAGT
CTTCGAGCGCTGTTTCACATTTTCAACAACTGGATAAGCTTCGCATGGTTTTTGAAGAGTATAAAGTTTGTCTCAGCTATAGATGTGCAGACATGGATAGGGAGATCCCT
GCTTTAATGGGTGTGTCAAAGACTATTCTGGACAATGTCATATTTGTTCACCAAGATGAAACTAACGGGCCATTGCAAGATCCTTCGACATCAAAGAAGAAATTTGATGA
TATTTGCTCTGTCACAAGTACTAGTGCCTTAAACATGGAGATAACCAGGACTGAATTTTCAGGACTGTTCTCTACAAAGCATTGCCATCAGGCTCCCTAG

mRNA sequence

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Protein sequence

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MINKVFGALSTVSTIFADGMRQMFDPFERVARAHHVCPGCERPFTAEEEDEFVKKQRVKAASSAEHMKVLAVESSSAVSHFQQLDKLRMVFEEYKVCLSYRCADMDREIP
ALMGVSKTILDNVIFVHQDETNGPLQDPSTSKKKFDDICSVTSTSALNMEITRTEFSGLFSTKHCHQAP

Spg031380 (gene) of Sponge gourd (cylindrica) v1 genome