CuGenDBv2

Gene ID	Spg032038
Organism	Luffa cylindrica (Sponge gourd (cylindrica) v1)
Description	DNA replication ATP-dependent helicase/nuclease DNA2
Genome location	scaffold11:42149865..42165312
RNA-Seq Expression	Spg032038
Synteny	Spg032038
Gene Ontology terms	GO:0071932 - replication fork reversal (biological process) GO:0005737 - cytoplasm (cellular component) GO:0003723 - RNA binding (molecular function) GO:0004386 - helicase activity (molecular function) GO:0017108 - 5'-flap endonuclease activity (molecular function)
InterPro domains	IPR014808 - DNA replication factor Dna2, N-terminal IPR027417 - P-loop containing nucleoside triphosphate hydrolase IPR041677 - DNA2/NAM7 helicase, helicase domain IPR041679 - DNA2/NAM7 helicase-like, C-terminal IPR045055 - DNA2/NAM7-like helicase

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0049091.1 DNA replication ATP-dependent helicase/nuclease DNA2 [Cucumis melo var. makuwa]

0.0e+00

75.16

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Query:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSDAVLA
        MPPRKKP+SSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQK T  TSDSKTDV +S+NRGDDRN+ R DSKD   AAA ATAQK E R+L VSDAVLA
Subjt:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSDAVLA

Query:  SENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLPETI
        SENPK PQ NDAS S LNTTPENLIAA GN GDD SNELSPEFSKSVSLKRFKFSPGM     LIKQSQ+EGT  DEITWKISPVNERLQAVSKQLPETI
Subjt:  SENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLPETI

Query:  RVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGSRVH
        RVLANSSRLSSLRIRQCSRNK                      TS V+PG+FEQLSSPN KPSE S+ASLNK GLKR+NPKHD+EPNGVA DSL+GS V 
Subjt:  RVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGSRVH

Query:  NSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDTVMK
        NS SPF+TPPSLSY DK+AND A ACNEAPDHPILRPHKKALLELLDQVEDVISVDTV S IDLE+DSSEL+GR GN LTT+VDSAAM++PK++ DTV K
Subjt:  NSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDTVMK

Query:  ASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTC
          PCDFLVLEVTEKCELADT GVKRSYK+LRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVD DNNFVILHPD LVSGTRVAGHLTC
Subjt:  ASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTC

Query:  PRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEFR
         RRSVLDERL+SNEQSI+ALIGTLLH   QAGL+E  PTVAFLEEVSR VLQKSMENVYACGANEKDIR TMNEA+PKILHWI +FKGPMG KAP+IEFR
Subjt:  PRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEFR

Query:  SDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVH-------TTYVR-------EVQ
        S+DGP+KVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMS+YNKCA NVMPLEFKTGK+PAGQA ++   C  D            Y+R        VQ
Subjt:  SDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVH-------TTYVR-------EVQ

Query:  RSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDHLKASHGIFL
        RSDLVGLIMRRNELANNILKASTAQLLPPMLQ P+VCKGCRHLDVCT+YHK                   MQNGSKE+SGLGVLF++HTDHL+ASH IF 
Subjt:  RSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDHLKASHGIFL

Query:  QHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDHRINYRFVCQ
        QHWERL+DLEAKE E                                   LVKRGVWHS + +KNQTSTCLSSIVLSTLDDQPHCTFEKD+RI+YRFV Q
Subjt:  QHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDHRINYRFVCQ

Query:  DLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDEFMTSFAVMRF
                DSNDDSS+ ASI+EMDSSLRVGDYVILSTDSG+LTLASGIITDLS+LH+ VSFSKRLRLPGSTSSTEA DL KQVWRIDKDEFMTSFAVMRF
Subjt:  DLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDEFMTSFAVMRF

Query:  NLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRGVSILLTSYT
        NLVQLFLQGEQN HLRKLIVDL APRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRGVSILLTSYT
Subjt:  NLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRGVSILLTSYT

Query:  NTAVDNLLIKLKSQP---LLLG--------------SDFAYYLVFFSLDLDALLFVTGK-----MLFDRVEHTKCGRHQNEI------------------
        NTAVDNLLIKLKSQ    + +G              S     +++F + +  LL+VT K     +    VE  +    Q ++                  
Subjt:  NTAVDNLLIKLKSQP---LLLG--------------SDFAYYLVFFSLDLDALLFVTGK-----MLFDRVEHTKCGRHQNEI------------------

Query:  -----------------GP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETAN
                         GP                       EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETAN
Subjt:  -----------------GP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETAN

Query:  AKLEFSSLKLSSSWLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKY
        AKL+FSS KLSSSWLKE LNPCKPVIFVCTDLLPAYETRDHKIVNNP+EANIL+EVTKGLLDGGIKGN+VGIITPYNSQASIIRLAI IASVE+HTIDKY
Subjt:  AKLEFSSLKLSSSWLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKY

Query:  QGRDKDCILVSFVRSSENPKSCTTSLLGDWHRINVAITRAK
        QGRDKDCILVSFVRSSENPKSCTTS+LGDWHRINVAITRAK
Subjt:  QGRDKDCILVSFVRSSENPKSCTTSLLGDWHRINVAITRAK

XP_008438250.1 PREDICTED: DNA replication ATP-dependent helicase/nuclease DNA2 [Cucumis melo]

0.0e+00

75.84

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Query:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSDAVLA
        MPPRKKP+SSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQK T  TSDSKTDV +S+NRGDDRN+ R DSKD   AAA ATAQK E R+L VSDAVLA
Subjt:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSDAVLA

Query:  SENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLPETI
        SENPK PQ NDAS S LNTTPENLIAA GN GDD SNELSPEFSKSVSLKRFKFSPGM     LIKQSQ+EGT  DEITWKISPVNERLQAVSKQLPETI
Subjt:  SENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLPETI

Query:  RVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGSRVH
        RVLANSSRLSSLRIRQCSRNK                      TS V+PG+FEQLSSPN KPSE S+ASLNK GLKR+NPKHD+EPNGVA DSL+GS V 
Subjt:  RVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGSRVH

Query:  NSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDTVMK
        NS SPF+TPPSLSY DK+AND A ACNEAPDHPILRPHKKALLELLDQVEDVISVDTV S IDLE+DSSEL+GR GN LTT+VDSAAM++PK++ DTV K
Subjt:  NSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDTVMK

Query:  ASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTC
          PCDFLVLEVTEKCELADT GVKRSYK+LRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVD DNNFVILHPD LVSGTRVAGHLTC
Subjt:  ASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTC

Query:  PRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEFR
         RRSVLDERL+SNEQSI+ALIGTLLH   QAGL+E  PTVAFLEEVSR VLQKSMENVYACGANEKDIR TMNEA+PKILHWI +FKGPMG KAP+IEFR
Subjt:  PRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEFR

Query:  SDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE----------------
        S+DGP+KVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMS+YNKCA NVMPLEFKTGK+PAGQ+ +    C   +++T  + E                
Subjt:  SDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE----------------

Query:  -------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDH
               VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQ P+VCKGCRHLDVCT+YHK                   MQNGSKE+SGLGVLF++HTDH
Subjt:  -------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDH

Query:  LKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDH
        L+ASH IF QHWERL+DLEAKE E                                   LVKRGVWHS + +KNQTSTCLSSIVLSTLDDQPHCTFEKD+
Subjt:  LKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDH

Query:  RINYRFVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDEF
        RI+YRFV Q        DSNDDSS+ ASI+EMDSSLRVGDYVILSTDSG+LTLASGIITDLS+LH+ VSFSKRLRLPGSTSSTEA DL KQVWRIDKDEF
Subjt:  RINYRFVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDEF

Query:  MTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRG
        MTSFAVMRFNLVQLFLQGEQN HLRKLIVDL APRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRG
Subjt:  MTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRG

Query:  VSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDAL-----------------LFVTGKML----FDRVEHTKCGRH--QNEI
        VSILLTSYTNTAVDNLLIKLKSQ    + +G   A +       F  L++ ++                 L +T  +L    FD     + G+      +
Subjt:  VSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDAL-----------------LFVTGKML----FDRVEHTKCGRH--QNEI

Query:  GP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSWLKE
        GP                       EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKL+FSS KLSSSWLKE
Subjt:  GP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSWLKE

Query:  ALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCILVSFVRSSE
         LNPCKPVIFVCTDLLPAYETRDHKIVNNP+EANIL+EVTKGLLDGGIKGN+VGIITPYNSQASIIRLAI IASVE+HTIDKYQGRDKDCILVSFVRSSE
Subjt:  ALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCILVSFVRSSE

Query:  NPKSCTTSLLGDWHRINVAITRAK
        NPKSCTTS+LGDWHRINVAITRAK
Subjt:  NPKSCTTSLLGDWHRINVAITRAK

XP_022924798.1 DNA replication ATP-dependent helicase/nuclease DNA2 isoform X1 [Cucurbita moschata]

0.0e+00

75.86

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Query:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAM-ATAQKPELRLLPVSDAVL
        MPPRKK NSSSKK NSNQQS+PSKFGIQHFF+RHSQN AHSQKLTPRTSDSKTDVS+S++RGDD N+ R D KDA AAA +  TAQK ELR+LPVSDAVL
Subjt:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAM-ATAQKPELRLLPVSDAVL

Query:  ASENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLPET
        ASENPK+PQGNDA SSSL+TTPE LIAA GNAG D SNELSP+FSKS SLKR KFSPGM     LIKQSQ+EGTTNDEITWKISPVNERLQAVSKQLPET
Subjt:  ASENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLPET

Query:  IRVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGSRV
        IRVLANSSRL+SLRIRQCS+NK                      TS V+ G+FEQLSS N KPSE SVASL+K GLKRL  KHD EPNGVAIDSL+GSRV
Subjt:  IRVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGSRV

Query:  HNSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDTVM
         NSQSPFRTPPSLSY DK AND      E+PDHPILRPHKKALLELLDQVEDVI+VDTV S IDLEEDSSEL+GRNG  LT  VDSAA ++ +KIPDTVM
Subjt:  HNSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDTVM

Query:  KASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLT
        KASPCDFLVLEVTEKCELADTS VKRSYKVLRLLNEQSGEERAVYLW+DWFDSIIAPGDTVNVIGEFDDQGRCHVDHD NFVILHPD+LVSGTRVAGHLT
Subjt:  KASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLT

Query:  CPRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEF
        CPRRSVLDERL+SNEQSISALIGTLLH   QAGL+EETPTVAFLEEVSR+VLQKSME+VYACGANEKDI +TMNEA+PKILHWITLFK PMG KAPTIEF
Subjt:  CPRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEF

Query:  RSDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE---------------
        RSDDGPRKVSISEVIDIEEMAWAPKYGLKG+IDASVRV V+SNYN C ENV+PLEFKTGK+PAGQ+ +    C   +++T  + E               
Subjt:  RSDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE---------------

Query:  --------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTD
                VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIP+VCKGCRHLDVCT+YHK                   MQNGSKESSGLG LFD++TD
Subjt:  --------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTD

Query:  HLKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKD
        HLKASHGIF QHWERL+DLEAKETE                                   LVKRGVWH+ + EKNQTSTCLSSIVLSTLD QPHCT EKD
Subjt:  HLKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKD

Query:  HRINYRFVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDE
        +RI+YRFVC   SS  LKDSN DSS+  S N+MDSSLRVGDYVILSTDSGNLTLASGII DLS+LHI VSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDE
Subjt:  HRINYRFVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDE

Query:  FMTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMR
        FMTSFA+MRFNLVQL LQGEQN HLRKLIVDL APRFD GCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMR
Subjt:  FMTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMR

Query:  GVSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDAL-----------------LFVTGKML----FDRVEHTKCGRH--QNE
        GVSILLTSYTNTAVDNLLIKLKSQ    + +G   A +       F  L++ ++                 L +T  +L    FD     + G+      
Subjt:  GVSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDAL-----------------LFVTGKML----FDRVEHTKCGRH--QNE

Query:  IGP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSWLK
        +GP                       EA+ENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFS LKLSSSWLK
Subjt:  IGP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSWLK

Query:  EALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCILVSFVRSS
        E +NPCKPVIFVCTDLLPAYETRDHKIVNNPIEANIL+EVTKGLLDGGI GNDVGIITPYNSQASIIRLAI IASVEIHTIDKYQGRDKDCILVSFVRSS
Subjt:  EALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCILVSFVRSS

Query:  ENPKSCTTSLLGDWHRINVAITRAK
        ENPKSCTTSLLGDWHRINVAITRAK
Subjt:  ENPKSCTTSLLGDWHRINVAITRAK

XP_023528556.1 DNA replication ATP-dependent helicase/nuclease DNA2 isoform X1 [Cucurbita pepo subsp. pepo]

0.0e+00

75.84

Show/hide

Query:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAA---MATAQKPELRLLPVSDA
        MPPRKK NSSSKK NSNQQS+PSKFGIQHFF+RHSQN AHSQKLTPRTSDSKTDVS+S++RGDD N+ R D KDA AAAA     TAQK ELR+LPVS+A
Subjt:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAA---MATAQKPELRLLPVSDA

Query:  VLASENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLP
        VLASENPK+PQGNDA SSSL+TTPE LIAA GNAG D SNELSP+FSKSVSLKR KFSPGM     LIKQSQ+EGTTNDEITWKISPVNERLQAVSKQLP
Subjt:  VLASENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLP

Query:  ETIRVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGS
        ETIRVLANSSRL+SLRIRQCS+NK                      TS  + G+FEQLSSPN KPSE SVASL+K GLKRL  KHD EPNGVAIDSL+GS
Subjt:  ETIRVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGS

Query:  RVHNSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDT
        RV NSQSPFRTPPSLSY DK AND      EAPDHPILRPHKKALLELLDQVEDVI+VDTV S IDLEEDS EL+GRNG  LT  VDSAA ++ +KIPDT
Subjt:  RVHNSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDT

Query:  VMKASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGH
        VMKASPCDFLVLEVTEKCELADTS VKRSYKVLRLLNEQSGEERAVYLW+DWFDSIIAPGDTVNVIGEFDDQGRCHVDH+ NFVILHPD+LVSGTRVAGH
Subjt:  VMKASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGH

Query:  LTCPRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTI
        LTCPRRSVLDERL+SNEQSISALIGTLLH   QAGL+EETPTVAFLEEVSR+VLQKSME+VYACGANEKDI +TMNEA+PKILHWITLFK PMG KAPTI
Subjt:  LTCPRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTI

Query:  EFRSDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE-------------
        EFRSDDGPRKVSISEVIDIEEMAWAPKYGLKG+IDASVRV V SNYN C ENV+PLEFKTGK+PAGQ+ +    C   +++T  + E             
Subjt:  EFRSDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE-------------

Query:  ----------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTH
                  VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIP+VCKGCRHLDVCT+YHK                   MQNGSKESSGLG LFD++
Subjt:  ----------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTH

Query:  TDHLKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFE
        TDHLKASHGIF QHWERL+DLEAKETE                                   LVKRGVWH+ +AEKNQTSTCLSSIVLSTLD QPHCT E
Subjt:  TDHLKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFE

Query:  KDHRINYRFVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDK
        KD+RI+YRFV Q LSS  LKDSN DSS+  S N+MDSSLRVGDYVILSTDSGNLTLASGII DLS+LHI VSFSKRLRLPGSTSSTEAHDLMKQVWRIDK
Subjt:  KDHRINYRFVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDK

Query:  DEFMTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALL
        DEFMTSFA+MRFNLVQL LQGEQN HLRKLIVDL APRFD GCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALL
Subjt:  DEFMTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALL

Query:  MRGVSILLTSYTNTAVDNLLIKLKSQ-------------------------------PLLLGSDFAYYLVFFSLDLDALLFVTGKM---LFDRVEHTK--
        MRGVSILLTSYTNTAVDNLLIKLKSQ                                + +  D    +    L L + L V  K    + D    T   
Subjt:  MRGVSILLTSYTNTAVDNLLIKLKSQ-------------------------------PLLLGSDFAYYLVFFSLDLDALLFVTGKM---LFDRVEHTK--

Query:  --------------CGRHQNEIGP-----EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSS
                       G H  ++ P     EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFS LKLSSS
Subjt:  --------------CGRHQNEIGP-----EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSS

Query:  WLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCILVSFV
        WLKE +NPCKPVIFVCTDLLPAYETRDHKIVNNPIEANIL+EVTKGLLDGGI GNDVGIITPYNSQASIIRLAI IASVEIHTIDKYQGRDKDCILVSFV
Subjt:  WLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCILVSFV

Query:  RSSENPKSCTTSLLGDWHRINVAITRAK
        RSSENPKSCTTSLLGDWHRINVAITRAK
Subjt:  RSSENPKSCTTSLLGDWHRINVAITRAK

XP_038878324.1 DNA replication ATP-dependent helicase/nuclease JHS1 [Benincasa hispida]

0.0e+00

76.62

Show/hide

Query:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSDAVLA
        MPPRKKP+SSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQK+T +TSDSKTDVSNS+NRGDD  V R DSKDA AA    TAQK + R+L VSDAVLA
Subjt:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSDAVLA

Query:  SENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLPETI
        SENPK+ QG DAS S LNTTPENLIAA GNAGDD SNELSPEFSKSVSLKRFKFSPGM     LIKQSQ+EGTTNDEITWKISPVNERLQAVSKQLPETI
Subjt:  SENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLPETI

Query:  RVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGSRVH
        RVLANSSRLSSLRIRQCSRNK                      TS V+PG+FEQLSSPNLKPSE SVASLNK G KRLNPKHDMEPN VA  S + SRV 
Subjt:  RVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGSRVH

Query:  NSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDTVMK
        NSQSPF+TPPSLSY DKIANDAA ACNEAPDHPILRPHK+ALLELLDQVEDVI+VDTV S IDLEEDSSEL+GRNG+ LTT+VDSAA ++PKKIPDTV  
Subjt:  NSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDTVMK

Query:  ASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTC
          P DFLVLEVTEKCELADTSG KRSYKVLRLLNEQSGEERAVYLW+DWFDSIIAPGDTVNVIGEFDD GRCHVDHDNNF+ILHPDILVSGTRVAGHLTC
Subjt:  ASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTC

Query:  PRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEFR
        PRRSVLDERLKSNEQSISALIGTLLH   QAGL+EE PTVAFL+EVSR VLQKSMENVYACGANEKDI   MNEA+PKILHWIT+FK PMG K PTIEFR
Subjt:  PRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEFR

Query:  SDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE----------------
        S+DGPRKVSISEVIDIEEMAWAPKYGLKG+IDASVRVN+MSNYNKCAENVMPLEFKTGK+PAGQ+ +    C   +++T  + E                
Subjt:  SDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE----------------

Query:  -------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDH
               VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIP+VCKGCRHLDVCT+YHK                   MQNGSKE+SGLGVLFD+HTDH
Subjt:  -------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDH

Query:  LKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDH
         KASHGIF QHWERL+DLEAKE E                                   LVKRGVWHS +AEKNQTST LSSIVLSTLD QPHCTFEKD+
Subjt:  LKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDH

Query:  RINYRFVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDEF
        RI+YRFV QDL S   KDSN DSS+ ASIN+MDSSLRVGDYVILSTDSG+LTLASGIITDLS+LHI VSFSKRLRLPGSTSSTEA DLM+QVWRIDKDEF
Subjt:  RINYRFVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDEF

Query:  MTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRG
        MTSFAVMRFNLVQLFLQGEQN HLRKLIVDL APRFD GCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRG
Subjt:  MTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRG

Query:  VSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDAL-----------------LFVTGKML----FDRVEHTKCGRH--QNEI
        VSILLTSYTNTAVDNLLIKLKSQ    + +G   A +       F  L+++++                 L +T  +L    FD     + G+      +
Subjt:  VSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDAL-----------------LFVTGKML----FDRVEHTKCGRH--QNEI

Query:  GP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSWLKE
        GP                       EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLE SS KLSSSWLKE
Subjt:  GP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSWLKE

Query:  ALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCILVSFVRSSE
         L+PCKPVIFVCTDLLPAYETRDHKIVNNPIEANIL+EVTKGLLDGGIKGN+VGIITPYNSQASIIRLAI IASVE+HTIDKYQGRDKDCILVSFVRSSE
Subjt:  ALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCILVSFVRSSE

Query:  NPKSCTTSLLGDWHRINVAITRAK
        NPKSCTTS+LGDWHRINVAITRAK
Subjt:  NPKSCTTSLLGDWHRINVAITRAK

TrEMBL top hits

e value

%identity

Alignment

A0A0A0L7S1 Uncharacterized protein

0.0e+00

75.56

Show/hide

Query:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSDAVLA
        MPPRKKP  SSKKLNSNQQSQPSKFGI+HFFERHSQNV+HSQK++ +TSDSKTDVSNS+NRGDDRN+ R DSKDA  AAA ATAQK E R+L VSDAVLA
Subjt:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSDAVLA

Query:  SENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLPETI
        SENPK+ Q NDAS S LNTTPENLIAA GN GDD SNELSPEFSKSVSLKRFKFSPGM     LIKQSQ+EGT  DEITWKISPVNERLQAVSKQLPETI
Subjt:  SENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLPETI

Query:  RVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGSRVH
        RVLANSSRLSSLRIRQCSRNK                      TS V+ G+FEQLSSPN KPSE S+ASLNK GLKR+NPKHD EP GV  DSL+ SRV 
Subjt:  RVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGSRVH

Query:  NSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDTVMK
        NS S F+TPPSLSY DK+AND A ACNEAPDHPILRPHKKALLELLDQVEDVI+VDTV S IDL +DSSEL+GRNG  LT +VDSAAM+IPK++ DTVMK
Subjt:  NSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDTVMK

Query:  ASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTC
        A PCDFLVLEVTEKCELADT GVKRSYKVLRLLNEQSGEERA YLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVD DNNFVILHPDILVSGTRVAGHLTC
Subjt:  ASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTC

Query:  PRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEFR
        PRRSVLDERLKSNEQS++ALIGTLLH   QAGL+EE P VAFLEEVSR VLQKSMENVYACGANEKDIR TMNEA+PKILHWI +FKGPMG KAP+IEFR
Subjt:  PRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEFR

Query:  SDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE----------------
        S+D PRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMS+YNKCA NVMPLEFKTGK+PAGQ+ +    C   +++T  + E                
Subjt:  SDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE----------------

Query:  -------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDH
               VQRSDLVGLIMRRNELANNILKASTAQ LPPMLQIP+VCKGCRHLDVCT+YHK                   MQNGSKE+SGLGVLF++HTDH
Subjt:  -------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDH

Query:  LKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDH
        L+ASHGIF QHWERL+DLEAKE E                                   LVKRGVWHS + +KNQTSTCLSSIVLSTLDDQPHCTFEKD+
Subjt:  LKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDH

Query:  RINYRFVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDEF
        RI+Y FV Q        DSN+DSS+ ASIN+MDSSLRVGDYVILSTDSG+LTLASGIITDLS++H+ VSFSKRLRLPGSTSSTEA DLMKQVWRIDKDEF
Subjt:  RINYRFVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDEF

Query:  MTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRG
        MTSFAVMRFNLVQLFLQGEQN HLRKLIVDL APRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRG
Subjt:  MTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRG

Query:  VSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDAL-----------------LFVTGKML----FDRVEHTKCGRH--QNEI
        VSILLTSYTN+AVDNLLIKLKSQ    + +G   A +       F  L++ ++                 L +T  +L    FD     + G+      +
Subjt:  VSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDAL-----------------LFVTGKML----FDRVEHTKCGRH--QNEI

Query:  GP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSWLKE
        GP                       EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSS KLSSSWLKE
Subjt:  GP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSWLKE

Query:  ALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCILVSFVRSSE
         LNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANIL+EVTKGLLDGGIKG++VGIITPYNSQASIIRLAI IASVE+HTIDKYQGRDKDCILVSFVRSSE
Subjt:  ALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCILVSFVRSSE

Query:  NPKSCTTSLLGDWHRINVAITRAK
        NPKSCTTSLLGDWHRINVAITRAK
Subjt:  NPKSCTTSLLGDWHRINVAITRAK

A0A1S3AVX8 DNA replication ATP-dependent helicase/nuclease DNA2

0.0e+00

75.84

Show/hide

Query:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSDAVLA
        MPPRKKP+SSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQK T  TSDSKTDV +S+NRGDDRN+ R DSKD   AAA ATAQK E R+L VSDAVLA
Subjt:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSDAVLA

Query:  SENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLPETI
        SENPK PQ NDAS S LNTTPENLIAA GN GDD SNELSPEFSKSVSLKRFKFSPGM     LIKQSQ+EGT  DEITWKISPVNERLQAVSKQLPETI
Subjt:  SENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLPETI

Query:  RVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGSRVH
        RVLANSSRLSSLRIRQCSRNK                      TS V+PG+FEQLSSPN KPSE S+ASLNK GLKR+NPKHD+EPNGVA DSL+GS V 
Subjt:  RVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGSRVH

Query:  NSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDTVMK
        NS SPF+TPPSLSY DK+AND A ACNEAPDHPILRPHKKALLELLDQVEDVISVDTV S IDLE+DSSEL+GR GN LTT+VDSAAM++PK++ DTV K
Subjt:  NSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDTVMK

Query:  ASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTC
          PCDFLVLEVTEKCELADT GVKRSYK+LRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVD DNNFVILHPD LVSGTRVAGHLTC
Subjt:  ASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTC

Query:  PRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEFR
         RRSVLDERL+SNEQSI+ALIGTLLH   QAGL+E  PTVAFLEEVSR VLQKSMENVYACGANEKDIR TMNEA+PKILHWI +FKGPMG KAP+IEFR
Subjt:  PRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEFR

Query:  SDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE----------------
        S+DGP+KVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMS+YNKCA NVMPLEFKTGK+PAGQ+ +    C   +++T  + E                
Subjt:  SDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE----------------

Query:  -------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDH
               VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQ P+VCKGCRHLDVCT+YHK                   MQNGSKE+SGLGVLF++HTDH
Subjt:  -------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDH

Query:  LKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDH
        L+ASH IF QHWERL+DLEAKE E                                   LVKRGVWHS + +KNQTSTCLSSIVLSTLDDQPHCTFEKD+
Subjt:  LKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDH

Query:  RINYRFVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDEF
        RI+YRFV Q        DSNDDSS+ ASI+EMDSSLRVGDYVILSTDSG+LTLASGIITDLS+LH+ VSFSKRLRLPGSTSSTEA DL KQVWRIDKDEF
Subjt:  RINYRFVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDEF

Query:  MTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRG
        MTSFAVMRFNLVQLFLQGEQN HLRKLIVDL APRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRG
Subjt:  MTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRG

Query:  VSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDAL-----------------LFVTGKML----FDRVEHTKCGRH--QNEI
        VSILLTSYTNTAVDNLLIKLKSQ    + +G   A +       F  L++ ++                 L +T  +L    FD     + G+      +
Subjt:  VSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDAL-----------------LFVTGKML----FDRVEHTKCGRH--QNEI

Query:  GP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSWLKE
        GP                       EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKL+FSS KLSSSWLKE
Subjt:  GP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSWLKE

Query:  ALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCILVSFVRSSE
         LNPCKPVIFVCTDLLPAYETRDHKIVNNP+EANIL+EVTKGLLDGGIKGN+VGIITPYNSQASIIRLAI IASVE+HTIDKYQGRDKDCILVSFVRSSE
Subjt:  ALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCILVSFVRSSE

Query:  NPKSCTTSLLGDWHRINVAITRAK
        NPKSCTTS+LGDWHRINVAITRAK
Subjt:  NPKSCTTSLLGDWHRINVAITRAK

A0A5A7U646 DNA replication ATP-dependent helicase/nuclease DNA2

0.0e+00

75.16

Show/hide

Query:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSDAVLA
        MPPRKKP+SSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQK T  TSDSKTDV +S+NRGDDRN+ R DSKD   AAA ATAQK E R+L VSDAVLA
Subjt:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSDAVLA

Query:  SENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLPETI
        SENPK PQ NDAS S LNTTPENLIAA GN GDD SNELSPEFSKSVSLKRFKFSPGM     LIKQSQ+EGT  DEITWKISPVNERLQAVSKQLPETI
Subjt:  SENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLPETI

Query:  RVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGSRVH
        RVLANSSRLSSLRIRQCSRNK                      TS V+PG+FEQLSSPN KPSE S+ASLNK GLKR+NPKHD+EPNGVA DSL+GS V 
Subjt:  RVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGSRVH

Query:  NSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDTVMK
        NS SPF+TPPSLSY DK+AND A ACNEAPDHPILRPHKKALLELLDQVEDVISVDTV S IDLE+DSSEL+GR GN LTT+VDSAAM++PK++ DTV K
Subjt:  NSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDTVMK

Query:  ASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTC
          PCDFLVLEVTEKCELADT GVKRSYK+LRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVD DNNFVILHPD LVSGTRVAGHLTC
Subjt:  ASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTC

Query:  PRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEFR
         RRSVLDERL+SNEQSI+ALIGTLLH   QAGL+E  PTVAFLEEVSR VLQKSMENVYACGANEKDIR TMNEA+PKILHWI +FKGPMG KAP+IEFR
Subjt:  PRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEFR

Query:  SDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVH-------TTYVR-------EVQ
        S+DGP+KVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMS+YNKCA NVMPLEFKTGK+PAGQA ++   C  D            Y+R        VQ
Subjt:  SDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVH-------TTYVR-------EVQ

Query:  RSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDHLKASHGIFL
        RSDLVGLIMRRNELANNILKASTAQLLPPMLQ P+VCKGCRHLDVCT+YHK                   MQNGSKE+SGLGVLF++HTDHL+ASH IF 
Subjt:  RSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDHLKASHGIFL

Query:  QHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDHRINYRFVCQ
        QHWERL+DLEAKE E                                   LVKRGVWHS + +KNQTSTCLSSIVLSTLDDQPHCTFEKD+RI+YRFV Q
Subjt:  QHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDHRINYRFVCQ

Query:  DLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDEFMTSFAVMRF
                DSNDDSS+ ASI+EMDSSLRVGDYVILSTDSG+LTLASGIITDLS+LH+ VSFSKRLRLPGSTSSTEA DL KQVWRIDKDEFMTSFAVMRF
Subjt:  DLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDEFMTSFAVMRF

Query:  NLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRGVSILLTSYT
        NLVQLFLQGEQN HLRKLIVDL APRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRGVSILLTSYT
Subjt:  NLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRGVSILLTSYT

Query:  NTAVDNLLIKLKSQP---LLLG--------------SDFAYYLVFFSLDLDALLFVTGK-----MLFDRVEHTKCGRHQNEI------------------
        NTAVDNLLIKLKSQ    + +G              S     +++F + +  LL+VT K     +    VE  +    Q ++                  
Subjt:  NTAVDNLLIKLKSQP---LLLG--------------SDFAYYLVFFSLDLDALLFVTGK-----MLFDRVEHTKCGRHQNEI------------------

Query:  -----------------GP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETAN
                         GP                       EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETAN
Subjt:  -----------------GP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETAN

Query:  AKLEFSSLKLSSSWLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKY
        AKL+FSS KLSSSWLKE LNPCKPVIFVCTDLLPAYETRDHKIVNNP+EANIL+EVTKGLLDGGIKGN+VGIITPYNSQASIIRLAI IASVE+HTIDKY
Subjt:  AKLEFSSLKLSSSWLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKY

Query:  QGRDKDCILVSFVRSSENPKSCTTSLLGDWHRINVAITRAK
        QGRDKDCILVSFVRSSENPKSCTTS+LGDWHRINVAITRAK
Subjt:  QGRDKDCILVSFVRSSENPKSCTTSLLGDWHRINVAITRAK

A0A6J1EDH9 DNA replication ATP-dependent helicase/nuclease DNA2 isoform X1

0.0e+00

75.86

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Query:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAM-ATAQKPELRLLPVSDAVL
        MPPRKK NSSSKK NSNQQS+PSKFGIQHFF+RHSQN AHSQKLTPRTSDSKTDVS+S++RGDD N+ R D KDA AAA +  TAQK ELR+LPVSDAVL
Subjt:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAM-ATAQKPELRLLPVSDAVL

Query:  ASENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLPET
        ASENPK+PQGNDA SSSL+TTPE LIAA GNAG D SNELSP+FSKS SLKR KFSPGM     LIKQSQ+EGTTNDEITWKISPVNERLQAVSKQLPET
Subjt:  ASENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLPET

Query:  IRVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGSRV
        IRVLANSSRL+SLRIRQCS+NK                      TS V+ G+FEQLSS N KPSE SVASL+K GLKRL  KHD EPNGVAIDSL+GSRV
Subjt:  IRVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGSRV

Query:  HNSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDTVM
         NSQSPFRTPPSLSY DK AND      E+PDHPILRPHKKALLELLDQVEDVI+VDTV S IDLEEDSSEL+GRNG  LT  VDSAA ++ +KIPDTVM
Subjt:  HNSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDTVM

Query:  KASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLT
        KASPCDFLVLEVTEKCELADTS VKRSYKVLRLLNEQSGEERAVYLW+DWFDSIIAPGDTVNVIGEFDDQGRCHVDHD NFVILHPD+LVSGTRVAGHLT
Subjt:  KASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLT

Query:  CPRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEF
        CPRRSVLDERL+SNEQSISALIGTLLH   QAGL+EETPTVAFLEEVSR+VLQKSME+VYACGANEKDI +TMNEA+PKILHWITLFK PMG KAPTIEF
Subjt:  CPRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEF

Query:  RSDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE---------------
        RSDDGPRKVSISEVIDIEEMAWAPKYGLKG+IDASVRV V+SNYN C ENV+PLEFKTGK+PAGQ+ +    C   +++T  + E               
Subjt:  RSDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE---------------

Query:  --------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTD
                VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIP+VCKGCRHLDVCT+YHK                   MQNGSKESSGLG LFD++TD
Subjt:  --------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTD

Query:  HLKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKD
        HLKASHGIF QHWERL+DLEAKETE                                   LVKRGVWH+ + EKNQTSTCLSSIVLSTLD QPHCT EKD
Subjt:  HLKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKD

Query:  HRINYRFVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDE
        +RI+YRFVC   SS  LKDSN DSS+  S N+MDSSLRVGDYVILSTDSGNLTLASGII DLS+LHI VSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDE
Subjt:  HRINYRFVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDE

Query:  FMTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMR
        FMTSFA+MRFNLVQL LQGEQN HLRKLIVDL APRFD GCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMR
Subjt:  FMTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMR

Query:  GVSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDAL-----------------LFVTGKML----FDRVEHTKCGRH--QNE
        GVSILLTSYTNTAVDNLLIKLKSQ    + +G   A +       F  L++ ++                 L +T  +L    FD     + G+      
Subjt:  GVSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDAL-----------------LFVTGKML----FDRVEHTKCGRH--QNE

Query:  IGP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSWLK
        +GP                       EA+ENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFS LKLSSSWLK
Subjt:  IGP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSWLK

Query:  EALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCILVSFVRSS
        E +NPCKPVIFVCTDLLPAYETRDHKIVNNPIEANIL+EVTKGLLDGGI GNDVGIITPYNSQASIIRLAI IASVEIHTIDKYQGRDKDCILVSFVRSS
Subjt:  EALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCILVSFVRSS

Query:  ENPKSCTTSLLGDWHRINVAITRAK
        ENPKSCTTSLLGDWHRINVAITRAK
Subjt:  ENPKSCTTSLLGDWHRINVAITRAK

A0A6J1ISY1 DNA replication ATP-dependent helicase/nuclease DNA2 isoform X1

0.0e+00

75.61

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Query:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAA---MATAQKPELRLLPVSDA
        MPPRKK NSSSKKLNSNQQS+PSKFGIQHFF+RHSQN AHSQKLTPRTSDSKTDVS+S++RGDD N+ R D KDA AAAA     TAQK EL+ LPVSDA
Subjt:  MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAA---MATAQKPELRLLPVSDA

Query:  VLASENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLP
        VLASENPK+PQGNDA SSSL+TTPE LIAA GNAG D SNELSP+FSKSVSLKR KFSPGM     LIKQSQ+EGTTNDEITWKISPVNERLQAVSKQLP
Subjt:  VLASENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLP

Query:  ETIRVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGS
        ETIRVLANSSRL+SLRIRQCS+NK                      TS V+ G+FEQLSS N KPSE SV SL+K GLKRL  KHD EPNGVAIDSL+GS
Subjt:  ETIRVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGS

Query:  RVHNSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDT
        RV NSQSPFRTPPSLSY DK AND      EAPDHPILRPHKKALLELLDQVEDVI+VDTV   IDLEEDSSEL+GRNG  LT  VDSAA ++ +KIPDT
Subjt:  RVHNSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDT

Query:  VMKASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGH
        VMKASPCDFLVLEVTEKCELADTS VKRSYKVLRLLNEQSGEERAVYLW+DWFDSIIAPGDTVNVIGEFDDQ RCHVDHD NFVILHPD+LVSGTRVAGH
Subjt:  VMKASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGH

Query:  LTCPRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTI
        LTCPRRSVLDERL+SNEQSISALIGTLLH   QAGL+EETPTV FLEEVSR+VLQKSME+VYACGANEKDI +TMNEA+PKILHWITLFK PMG KAPTI
Subjt:  LTCPRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTI

Query:  EFRSDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE-------------
        EFRSDDGPRKVSISEVIDIEEMAWAPKYGLKG+IDASVRV V+SNYN C ENV+PLEFKTGK+PAGQ+ +    C   +++T  + E             
Subjt:  EFRSDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE-------------

Query:  ----------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTH
                  VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIP+VCKGCRHLDVCT+YHK                   MQNGSKESSGLG LFD++
Subjt:  ----------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTH

Query:  TDHLKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFE
        TDHLKASHG F QHWERL+DLEAKETE                                   LVKRGVWH+ +AEKNQTSTCLSSIVLSTLD QPHCT E
Subjt:  TDHLKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFE

Query:  KDHRINYRFVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDK
        KD+RI+YRFV Q LSS   KDSN DSS+  S N+MDSSLRVGDYVILSTDSGNLTLASGII DLS+LHI VSFSKRLRLPGSTSSTEAHDLMKQVWRIDK
Subjt:  KDHRINYRFVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDK

Query:  DEFMTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALL
        DEFMTSFA+MRFNLVQL LQGEQN HLRKLIVDL APRFD GCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALL
Subjt:  DEFMTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALL

Query:  MRGVSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDAL-----------------LFVTGKML----FDRVEHTKCGRH--Q
        MRGVSILLTSYTNTAVDNLLIKLKSQ    + +G   A +       F  L++ ++                 L +T  +L    FD     + G+    
Subjt:  MRGVSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDAL-----------------LFVTGKML----FDRVEHTKCGRH--Q

Query:  NEIGP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSW
          +GP                       EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFS LKLS+SW
Subjt:  NEIGP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSW

Query:  LKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCILVSFVR
        LKE +NPCKPVIFVCTDLLPAYETRDHKIVNNPIEANIL+EVTKGLLDGGI GNDVGIITPYNSQASIIRLAI I SVEIHTIDKYQGRDKDCILVSFVR
Subjt:  LKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCILVSFVR

Query:  SSENPKSCTTSLLGDWHRINVAITRAK
        SSENPKSCTTSLLGDWHRINVAITRAK
Subjt:  SSENPKSCTTSLLGDWHRINVAITRAK

SwissProt top hits

e value

%identity

Alignment

A0A1P8ASY1 DNA replication ATP-dependent helicase/nuclease JHS1

1.1e-304

45.95

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Query:  MPPRKKPNSSSKKLN----SNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSD
        MPPRKKP SS+ K N    +N  SQPS FGIQ  F RH QN       +  TS+S T  ++ V   D +NV    S  AV      T Q P         
Subjt:  MPPRKKPNSSSKKLN----SNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSD

Query:  AVLASENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQL
          L + N K  +  D                     D    E SP+ SK++     +FSPGM     LIKQSQ++     EITWKISPVNERL+A +K +
Subjt:  AVLASENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQL

Query:  PETIRVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNG
        P+ + +  NS  + S  IR CS NK++  +                 TS +     + LSSP+ K S+    + N+  ++R+NP  D E      + +N 
Subjt:  PETIRVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNG

Query:  SRVHNSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPD
        S   N  SPF+TPPSLS            C+ A        HKKALLELLDQVEDVI+VD   +  D+     + R ++ + +++ VD A  + P  +P 
Subjt:  SRVHNSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPD

Query:  TVMKASPCD-FLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVA
             +P   FLVLEV+EK     +S  +  YKVLRLL+E +G E A+YLW++WF S ++PGD++NVIGEFD  G+C VD  NNF+I+HPD LV+GTRVA
Subjt:  TVMKASPCD-FLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVA

Query:  GHLTCPRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAP
            CPRR+VLDERL+SNE +  AL+GTL H   QAGL +E+P+V  L+E +  V++KS+E++YACG +E D+R T+ +AIPK+L+WI  F+     +  
Subjt:  GHLTCPRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAP

Query:  TIEFRSDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE-----------
         ++F S  G + V +SEVIDIEEM+WAPKYGLKG+IDASVRV V S+ N   E +MPLEFK+GK P+GQ+ +  ++    +++T  + E           
Subjt:  TIEFRSDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE-----------

Query:  ------------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFD
                    VQRSDLVGLI+RRNELAN+IL AST Q LPPML+ P++C+ CRHLDVCT+YHK                      G+ ESSGLG +FD
Subjt:  ------------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFD

Query:  THTDHLKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCT
        TH  HL   H  FL+HW+RL+DLE +E                                    QL+++ + H H ++ + +++ LSS+VL   +   H  
Subjt:  THTDHLKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCT

Query:  FEKDHRINYRFVCQDLSSQSLKDSNDDSSSAASI--NEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVW
          K+ R  YRFV Q  S    + +++D     ++  +++D  LR GD VIL T+  +LT+A+GII D+S  HI VS SKRLRLP S  S+E  +L  ++W
Subjt:  FEKDHRINYRFVCQDLSSQSLKDSNDDSSSAASI--NEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVW

Query:  RIDKDEFMTSFAVMRFNLVQLFLQGEQNGH-LRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHA
        RI KDEFMTSF+VMRFNL+QLF+   QNGH +RK+IVDL  PRFD G I SQDPAISYIWSEK+LN+DQR+AI+KILTAKDYALILGMPGTGKTSTMVHA
Subjt:  RIDKDEFMTSFAVMRFNLVQLFLQGEQNGH-LRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHA

Query:  VKALLMRGVSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDALLFVTGKMLFDRVEHTKC---------GRHQN--------
        VKALL+RG SILL SYTN+AVDNLLIKLK+Q    L +G D A +       F ++++ ++  +  K+   +V  + C          R  +        
Subjt:  VKALLMRGVSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDALLFVTGKMLFDRVEHTKC---------GRHQN--------

Query:  ------EIGP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLK
               IGP                       EARENG+GISLF RLSEAHPQAIS LQ+QYRMCR IMELSNALIYGDRL CGS E A+A L  S+  
Subjt:  ------EIGP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLK

Query:  LSSSWLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCIL
         +S WLK+ L P + V+FV TD+L A+E RD   +NNP+EA+I++E+ + L++ G+   D+GIITPYNSQAS+I+ AI    VEIHTIDKYQGRDKDCIL
Subjt:  LSSSWLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCIL

Query:  VSFVRSSENPKSCTTSLLGDWHRINVAITRAK
        VSFVRS E P+S  +SLLGDWHRINVA+TRAK
Subjt:  VSFVRSSENPKSCTTSLLGDWHRINVAITRAK

D3ZG52 DNA replication ATP-dependent helicase/nuclease DNA2

9.9e-83

27.3

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Query:  KVLRLLNEQSGEERAVYLWEDWFDSI-IAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTCPRRSVLDERLK-SNEQSISALIGTLL
        K L +   Q GE+  + +  + + S+ + PGD +++ G+   +    VD D  + IL PD+L+SGT VA  + C RR+VL E  + S+  +   LIGT+L
Subjt:  KVLRLLNEQSGEERAVYLWEDWFDSI-IAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTCPRRSVLDERLK-SNEQSISALIGTLL

Query:  HQA--GLMEETPTVAFLEEVSRMVLQ--KSMENVYACGANEKDIRKTMNEAIPKILHWITLF--KGPMG-FKAPTIEFRSD----DGPRKVSISEVIDIE
        H+     + E+     L+E++   L+  + ++ +Y    ++ ++R  + E +P    W   F  KG    F    +   SD      P  + + + +DIE
Subjt:  HQA--GLMEETPTVAFLEEVSRMVLQ--KSMENVYACGANEKDIRKTMNEAIPKILHWITLF--KGPMG-FKAPTIEFRSD----DGPRKVSISEVIDIE

Query:  EMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLP-----AGQAILHGTSCPS-----DLVHTTYVREVQ-------RSDLVGLIMRRNEL
        E  W+P++GLKG ID +V V +  +  K    +MPLE KTGK        GQ IL+           +     Y++  Q         D   L+  RN+L
Subjt:  EMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLP-----AGQAILHGTSCPS-----DLVHTTYVREVQ-------RSDLVGLIMRRNEL

Query:  ANNIL----KASTAQ-----LLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDHLKASHGIFLQHWER
        A ++L    +A+  +      LP +++    CK C  +  C +Y +   +          +H  ++  G +     G      T HL  +H  +   W  
Subjt:  ANNIL----KASTAQ-----LLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDHLKASHGIFLQHWER

Query:  LVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDHRINYRFVCQDLSSQ
        ++ LE++  + +                            +H      + +W +  ++  ++  C+ S+V +    +P            + VC      
Subjt:  LVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDHRINYRFVCQDLSSQ

Query:  SLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNL-TLASGIITDLSNLHICVSFSKRL-RLPGSTSSTEAHDLMKQVWRIDKDEFMTSFAVMRFNLV
        + +  N    +        ++L  GD +ILS +   L  L+ G +  +    +     + L  LP +T           ++R+D++E          NL 
Subjt:  SLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNL-TLASGIITDLSNLHICVSFSKRL-RLPGSTSSTEAHDLMKQVWRIDKDEFMTSFAVMRFNLV

Query:  QLFLQGEQNGHLRKLIVDLVAPRFDG--GCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRGVSILLTSYTN
        +L    + +  LR+LI+D   P+F      +   D   +     K LN  QR+A+ K+L +KDY LI+GMPGTGKT+T+   V+ L   G S+LLTSYT+
Subjt:  QLFLQGEQNGHLRKLIVDLVAPRFDG--GCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRGVSILLTSYTN

Query:  TAVDNLLIKLK--------------------------------------------------------SQPLLLGSDFAYYLVFFSLDLDALLFVTGKMLF
        +AVDN+L+KL                                                         S P+     F + +V  +  +   + + G + F
Subjt:  TAVDNLLIKLK--------------------------------------------------------SQPLLLGSDFAYYLVFFSLDLDALLFVTGKMLF

Query:  DRVEHTKCGRHQN----EIGPEARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANA----------KLEFSSLKLS
         R      G H+      +  EAR  G+  SLF RL E +  A+  L  QYRM R IM LSN L Y  +L CGS+  ANA          +LEF +    
Subjt:  DRVEHTKCGRHQN----EIGPEARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANA----------KLEFSSLKLS

Query:  SSWLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAI---KIASVEIHTIDKYQGRDKDCI
        + WL     P  PV F+ TD +PA E  ++  V+N  EA ++  +T   +  G   +D+GII PY  Q   I   +    +  VE++T+DKYQGRDK  I
Subjt:  SSWLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAI---KIASVEIHTIDKYQGRDKDCI

Query:  LVSFVRSSENPKSCTTSLLGDWHRINVAITRAK
        LVSFVRS+E+       LL DW R+NVAITRAK
Subjt:  LVSFVRSSENPKSCTTSLLGDWHRINVAITRAK

P51530 DNA replication ATP-dependent helicase/nuclease DNA2

9.9e-83

27.76

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Query:  KVLRLLNEQSGEERAV-YLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTCPRRSVLDERLKSNEQSI-SALIGTLL
        K L +   QS E + +  L  DW    + PGD +++ G+        +D D  ++IL+PD+L+SGT +A  + C RR+VL E  +S++ +    LIGT+L
Subjt:  KVLRLLNEQSGEERAV-YLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTCPRRSVLDERLKSNEQSI-SALIGTLL

Query:  HQAGLMEETPTVAF----LEEVSRMVLQ--KSMENVYACGANEKDIRKTMNEAIPKILHWITLFK--------GPMGFKAPTIEFRSDDGPRKVSISEVI
        H+  + ++    +F    L+E++   +Q  + ++ +Y    ++ +I++ + + +P    W   F           M    P+ +   D+    + + + +
Subjt:  HQAGLMEETPTVAF----LEEVSRMVLQ--KSMENVYACGANEKDIRKTMNEAIPKILHWITLFK--------GPMGFKAPTIEFRSDDGPRKVSISEVI

Query:  DIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVREVQRSDLVG----------------------
        DIEE  W+P++GLKG ID +V V +   Y K    +MPLE KTGK     +I H     S +V  T + + +R+D                         
Subjt:  DIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVREVQRSDLVG----------------------

Query:  -LIMRRNELA----NNILKASTAQ-----LLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDHLKASH
         L+  RN++A    + I K++T Q      LP +++    CK C  +  C +Y +   + +     +PI+    ++                T HLK +H
Subjt:  -LIMRRNELA----NNILKASTAQ-----LLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDHLKASH

Query:  GIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDHRINYR
          +   W                             CL + + S    N    Q     +W    +E  ++ +C+ +++        H     D +  + 
Subjt:  GIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDHRINYR

Query:  FVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNL-TLASGIITDLSNLHICVSFSKRLR-LPGSTSSTEAHDLMKQVWRIDKDEFMTS
        F C+                A  +    ++L  GD VI+S +  +L  L+ G + +++   +     + L  LP ST           ++R+D++E    
Subjt:  FVCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNL-TLASGIITDLSNLHICVSFSKRLR-LPGSTSSTEAHDLMKQVWRIDKDEFMTS

Query:  FAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDG--GCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRGV
              NL +L      +  LR LI+D   P+F      +   D   +     K LN  QR+A+ K+L +KDY LI+GMPGTGKT+T+   V+ L   G 
Subjt:  FAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDG--GCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRGV

Query:  SILLTSYTNTAVDNLLIKL---KSQPLLLG---------SDFAYYLVFFSLDLDALLF---------------------VTGKMLFD--------RVEHT
        S+LLTSYT++AVDN+L+KL   K   L LG           F    +  S  + +L                       +  + +FD        ++   
Subjt:  SILLTSYTNTAVDNLLIKL---KSQPLLLG---------SDFAYYLVFFSLDLDALLF---------------------VTGKMLFD--------RVEHT

Query:  KC-------------GRHQN----EIGPEARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANA------------K
         C             G HQ      +  EAR  G+  SLF RL E +  A+  L  QYRM   IM LSN L Y  +L CGS++ ANA            +
Subjt:  KC-------------GRHQN----EIGPEARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANA------------K

Query:  LEFSSLKLSSSWLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIR--LAIKIASVEIHTIDKY
        LEF +    + WL     P  PV F+ TD +PA E  +   V+N  EA ++  +T   +  G   +D+GII PY  Q  II   LA  I  VE++T+DKY
Subjt:  LEFSSLKLSSSWLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIR--LAIKIASVEIHTIDKY

Query:  QGRDKDCILVSFVRSSENPKSCTTSLLGDWHRINVAITRAK
        QGRDK  +LVSFVRS  N       LL DW R+NVAITRAK
Subjt:  QGRDKDCILVSFVRSSENPKSCTTSLLGDWHRINVAITRAK

Q8QHA5 DNA replication ATP-dependent helicase/nuclease DNA2

1.4e-89

27.54

Show/hide

Query:  KRSYKVLRLLNEQSGEE-RAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTCPRRSVLDERLK-SNEQSISALI
        +R  K L +   Q G++     L +DW    I PGD +++ G         +  D  ++IL+PD+L+SGT +A  + C RRSVL E+ K  ++ S   L 
Subjt:  KRSYKVLRLLNEQSGEE-RAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTCPRRSVLDERLK-SNEQSISALI

Query:  GTLLHQAGLMEETPTVAFLEEVSRMVLQ------KSMENVYACGANEKDIRKTMNEAIPKILHWITLF-KGPMG-FKAPTIEFRSDDGPRKVSISEVIDI
        GT+LH   + +   T  F + V + +        K ++ +Y    N+ D+   + E +P +  W T F   P+   +    +  + D      +SE +DI
Subjt:  GTLLHQAGLMEETPTVAFLEEVSRMVLQ------KSMENVYACGANEKDIRKTMNEAIPKILHWITLF-KGPMG-FKAPTIEFRSDDGPRKVSISEVIDI

Query:  EEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVREVQRSDLVGLIMR--------------------
        EE  W+P++GLKG ID + RV +    +K    +MPLE KTGK     +I H +     +++T   +E +     GL++                     
Subjt:  EEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVREVQRSDLVGLIMR--------------------

Query:  --RNELA---NNIL-------KASTAQLLPPMLQIPSVCKGCRHLDVCTVYHK-VSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDHLKASHG
          RNEL+    N+L       K +T   LP M+     CK C  +  C +Y++ V  +      P  ++  +  +                T+HL   H 
Subjt:  --RNELA---NNIL-------KASTAQLLPPMLQIPSVCKGCRHLDVCTVYHK-VSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDHLKASHG

Query:  IFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDHRINYRF
         + + W  +  LEA                                 N+   ++ ++ +W   ++E+ +   C+ +++                R  +  
Subjt:  IFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDHRINYRF

Query:  VCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHI-CVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDEFMTSFA
           D+  Q L      S S  + N     L  GD V++S +   L L++G I ++ + +I C+     ++LP         DL+   +R+D +E      
Subjt:  VCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHI-CVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDEFMTSFA

Query:  VMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSE--KNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRGVSI
            NL +L      +  LRKLI+D   P F         P    I +   + LN  Q++A+ ++L +KDY LI+GMPGTGKT+T+   V+ L   G S+
Subjt:  VMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSE--KNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRGVSI

Query:  LLTSYTNTAVDNLLIKLK--------------------------------------------------------SQPLLLGSDFAYYLVFFSLDLDALLF
        LLTSYT++AVDN+L+KLK                                                        + P+     F + +V  +  +   + 
Subjt:  LLTSYTNTAVDNLLIKLK--------------------------------------------------------SQPLLLGSDFAYYLVFFSLDLDALLF

Query:  VTGKMLFDRVEHTKCGRHQNEIGP-----EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKL---
        +      DR      G HQ ++ P     EARE G+  SLF RL E + +A+  L  QYRM   IM LSN L+Y  RL C S+  +NA ++   +K    
Subjt:  VTGKMLFDRVEHTKCGRHQNEIGP-----EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKL---

Query:  --------SSSWLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIR---LAIKIASVEIHTIDK
                 S W+K+ L P  PV F+ T+ +PA ET +   ++N IEA ++  +TK  L  G + +D+GII PY  Q  +I     ++  ++VE++T+DK
Subjt:  --------SSSWLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIR---LAIKIASVEIHTIDK

Query:  YQGRDKDCILVSFVRSSENPKSCTTSLLGDWHRINVAITRAK
        YQGRDK  I+VSFVRS+ + K     LL DW R+NVA+TRAK
Subjt:  YQGRDKDCILVSFVRSSENPKSCTTSLLGDWHRINVAITRAK

Q9URU2 DNA replication ATP-dependent helicase/nuclease dna2

5.4e-89

28.19

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Query:  DFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTCPRRS
        ++ VLEV E     + +     ++ L+L+ E +     ++L  DW ++ I  GD++ V   FD      VD+D   +I+HP IL+S T VA    C R++
Subjt:  DFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTCPRRS

Query:  VLDERLKSNEQSISALI-GTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEFRSDD
        V+ +R+        A++ G +LH   Q  L      +  ++      ++  + ++Y    +  +IR+ ++  +P +   +  +          I  ++D+
Subjt:  VLDERLKSNEQSISALI-GTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEFRSDD

Query:  GPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKL-----PAGQAILHGTSCPSD-------------LVHTTYVREV
            + IS ++DIEE  W+P++GLKG IDA+V V +       +   +PLE KTG+         Q++L+ T   SD             L ++T    V
Subjt:  GPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKL-----PAGQAILHGTSCPSD-------------LVHTTYVREV

Query:  -QRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDHLKASHGI
           S L GLIM RN LA +  + S    LP M+    +C  C  +  C  + K+S K                  G   S+GL   ++     +K     
Subjt:  -QRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDTHTDHLKASHGI

Query:  FLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRG-VWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDHRINYRF
        F + WE+L++ E +                                      L+KRG V    T E       L  + ++  D    C    D   +Y+F
Subjt:  FLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRG-VWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDHRINYRF

Query:  VCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLP----------------GSTSSTEAHDLMK
                     ND+       N + S   VG+ V +S + G+ +LA G I  + +  I V    RL +P                G+   ++   +  
Subjt:  VCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLP----------------GSTSSTEAHDLMK

Query:  Q--VWRIDKDEFMTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTST
            +RIDKDEF +  A +R  L+   L  +    +R +I+ L  P+F    +   DP        K LN+DQ  A+ K   A+ Y+LILGMPGTGKT+T
Subjt:  Q--VWRIDKDEFMTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTST

Query:  MVHAVKALLMRGVSILLTSYTNTAVDNLLIKLK---SQPLLLGS--------------------DFAYYLVFF---------SLDLDALLFVTGKMLFDR
        +   +++LL +   ILLTS+T+ AVDN+LIKLK   S  + LGS                    D A    F+         SL +   +F   K  +  
Subjt:  MVHAVKALLMRGVSILLTSYTNTAVDNLLIKLK---SQPLLLGS--------------------DFAYYLVFF---------SLDLDALLFVTGKMLFDR

Query:  VEHTK-------------------CGRHQNEIGP-----EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKL
        ++                       G H  ++ P        ++GL +SLF  LSE HP+A++ L+ QYRM  DI  LS+ LIYG  L CGS+  +  KL
Subjt:  VEHTK-------------------CGRHQNEIGP-----EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKL

Query:  EFSSLKLSSS---------WLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIK-IASVE
              LS           W+ + +NP   VIF  TD +   E++ + I+ N  EA ++ +     L+ G+K + +GII+ Y SQ  ++   +K    +E
Subjt:  EFSSLKLSSS---------WLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIK-IASVE

Query:  IHTIDKYQGRDKDCILVSFVRSSENPKSCTTSLLGDWHRINVAITRAKVFSISGNSSDTAFFGNLFLNPHLMKAI
        I+T+D+YQGRDKD IL+SFVRS  N K+    LL DWHR+NVA++RAKV  I   S  T    N+    HL+K +
Subjt:  IHTIDKYQGRDKDCILVSFVRSSENPKSCTTSLLGDWHRINVAITRAKVFSISGNSSDTAFFGNLFLNPHLMKAI

Arabidopsis top hits

e value

%identity

Alignment

AT1G08840.1 DNA replication helicase, putative

2.6e-288

44.76

Show/hide

Query:  MPPRKKPNSSSKKLN----SNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSD
        MPPRKKP SS+ K N    +N  SQPS FGIQ  F RH QN       +  TS+S T  ++ V   D +NV    S  AV      T Q P         
Subjt:  MPPRKKPNSSSKKLN----SNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSD

Query:  AVLASENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQL
          L + N K  +  D                     D    E SP+ SK++     +FSPGM     LIKQSQ++     EITWKISPVNERL+A +K +
Subjt:  AVLASENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQL

Query:  PETIRVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNG
        P+ + +  NS        +QC  + +                     TS V+    + LSSP+ K S+    + N+  ++R+NP  D E      + +N 
Subjt:  PETIRVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNG

Query:  SRVHNSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPD
        S   N  SPF+TPPSLS            C+ A        HKKALLELLDQVEDVI+VD   +  D+     + R ++ + +++ VD A  + P  +P 
Subjt:  SRVHNSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPD

Query:  TVMKASPCD-FLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVA
             +P   FLVLEV+EK     +S  +  YKVLRLL+E +G E A+YLW++WF S ++PGD++NVIGEFD  G+C VD  NNF+I+HPD LV+GTRVA
Subjt:  TVMKASPCD-FLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVA

Query:  GHLTCPRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAP
            CPRR+VLDERL+SNE +  AL+GTL H   QAGL +E+P+V  L+E +  V++KS+E++YACG +E D+R T+ +AIPK+L+WI  F+     +  
Subjt:  GHLTCPRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAP

Query:  TIEFRSDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE-----------
         ++F S  G + V +SEVIDIEEM+WAPKYGLKG+IDASVRV V S+ N   E +MPLEFK+GK P+GQ+ +  ++    +++T  + E           
Subjt:  TIEFRSDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE-----------

Query:  ------------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFD
                    VQRSDLVGLI+RRNELAN+IL AST Q LPPML+                                         G+ ESSGLG +FD
Subjt:  ------------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFD

Query:  THTDHLKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCT
        TH  HL   H  FL+HW+RL+DLE +E                                    QL+++ + H H ++ + +++ LSS+VL   +   H  
Subjt:  THTDHLKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCT

Query:  FEKDHRINYRFVCQDLSSQSLKDSNDDSSSAASI--NEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVW
          K+ R  YRFV Q  S    + +++D     ++  +++D  LR GD VIL T+  +LT+A+GII D+S  HI VS SKRLRLP S  S+E  +L  ++W
Subjt:  FEKDHRINYRFVCQDLSSQSLKDSNDDSSSAASI--NEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVW

Query:  RIDKDEFMTSFAVMRFNLVQLFLQGEQNGH-LRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHA
        RI KDEFMTSF+VMRFNL+QLF+   QNGH +RK+IVDL  PRFD G I SQDPAISYIWSEK+LN+DQR+AI+KILTAKDYALILGMPGTGKTSTMVHA
Subjt:  RIDKDEFMTSFAVMRFNLVQLFLQGEQNGH-LRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHA

Query:  VKALLMRGVSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDALLFVTGKMLFDRVEHTKC---------GRHQN--------
        VKALL+RG SILL SYTN+AVDNLLIKLK+Q    L +G D A +       F ++++ ++  +  K+   +V  + C          R  +        
Subjt:  VKALLMRGVSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDALLFVTGKMLFDRVEHTKC---------GRHQN--------

Query:  ------EIGP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLK
               IGP                       EARENG+GISLF RLSEAHPQAIS LQ+QYRMCR IMELSNALIYGDRL CGS E A+A L  S+  
Subjt:  ------EIGP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLK

Query:  LSSSWLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCIL
         +S WLK+ L P + V+FV TD+L A+E RD   +NNP+EA+I++E+ + L++ G+   D+GIITPYNSQAS+I+ AI    VEIHTIDKYQGRDKDCIL
Subjt:  LSSSWLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCIL

Query:  VSFVRSSENPKSCTTSLLGDWHRINVAITRAK
        VSFVRS E P+S  +SLLGDWHRINVA+TRAK
Subjt:  VSFVRSSENPKSCTTSLLGDWHRINVAITRAK

AT1G08840.2 DNA replication helicase, putative

2.1e-301

45.67

Show/hide

Query:  MPPRKKPNSSSKKLN----SNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSD
        MPPRKKP SS+ K N    +N  SQPS FGIQ  F RH QN       +  TS+S T  ++ V   D +NV    S  AV      T Q P         
Subjt:  MPPRKKPNSSSKKLN----SNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSD

Query:  AVLASENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQL
          L + N K  +  D                     D    E SP+ SK++     +FSPGM     LIKQSQ++     EITWKISPVNERL+A +K +
Subjt:  AVLASENPKLPQGNDASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQL

Query:  PETIRVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNG
        P+ + +  NS        +QC  + +                     TS V+    + LSSP+ K S+    + N+  ++R+NP  D E      + +N 
Subjt:  PETIRVLANSSRLSSLRIRQCSRNKVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNG

Query:  SRVHNSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPD
        S   N  SPF+TPPSLS            C+ A        HKKALLELLDQVEDVI+VD   +  D+     + R ++ + +++ VD A  + P  +P 
Subjt:  SRVHNSQSPFRTPPSLSYSDKIANDAASACNEAPDHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPD

Query:  TVMKASPCD-FLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVA
             +P   FLVLEV+EK     +S  +  YKVLRLL+E +G E A+YLW++WF S ++PGD++NVIGEFD  G+C VD  NNF+I+HPD LV+GTRVA
Subjt:  TVMKASPCD-FLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEERAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVA

Query:  GHLTCPRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAP
            CPRR+VLDERL+SNE +  AL+GTL H   QAGL +E+P+V  L+E +  V++KS+E++YACG +E D+R T+ +AIPK+L+WI  F+     +  
Subjt:  GHLTCPRRSVLDERLKSNEQSISALIGTLLH---QAGLMEETPTVAFLEEVSRMVLQKSMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAP

Query:  TIEFRSDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE-----------
         ++F S  G + V +SEVIDIEEM+WAPKYGLKG+IDASVRV V S+ N   E +MPLEFK+GK P+GQ+ +  ++    +++T  + E           
Subjt:  TIEFRSDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAGQAILHGTSCPSDLVHTTYVRE-----------

Query:  ------------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFD
                    VQRSDLVGLI+RRNELAN+IL AST Q LPPML+ P++C+ CRHLDVCT+YHK                      G+ ESSGLG +FD
Subjt:  ------------VQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFD

Query:  THTDHLKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCT
        TH  HL   H  FL+HW+RL+DLE +E                                    QL+++ + H H ++ + +++ LSS+VL   +   H  
Subjt:  THTDHLKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCT

Query:  FEKDHRINYRFVCQDLSSQSLKDSNDDSSSAASI--NEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVW
          K+ R  YRFV Q  S    + +++D     ++  +++D  LR GD VIL T+  +LT+A+GII D+S  HI VS SKRLRLP S  S+E  +L  ++W
Subjt:  FEKDHRINYRFVCQDLSSQSLKDSNDDSSSAASI--NEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVW

Query:  RIDKDEFMTSFAVMRFNLVQLFLQGEQNGH-LRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHA
        RI KDEFMTSF+VMRFNL+QLF+   QNGH +RK+IVDL  PRFD G I SQDPAISYIWSEK+LN+DQR+AI+KILTAKDYALILGMPGTGKTSTMVHA
Subjt:  RIDKDEFMTSFAVMRFNLVQLFLQGEQNGH-LRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHA

Query:  VKALLMRGVSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDALLFVTGKMLFDRVEHTKC---------GRHQN--------
        VKALL+RG SILL SYTN+AVDNLLIKLK+Q    L +G D A +       F ++++ ++  +  K+   +V  + C          R  +        
Subjt:  VKALLMRGVSILLTSYTNTAVDNLLIKLKSQP---LLLGSDFAYY-----LVFFSLDLDALLFVTGKMLFDRVEHTKC---------GRHQN--------

Query:  ------EIGP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLK
               IGP                       EARENG+GISLF RLSEAHPQAIS LQ+QYRMCR IMELSNALIYGDRL CGS E A+A L  S+  
Subjt:  ------EIGP-----------------------EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLK

Query:  LSSSWLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCIL
         +S WLK+ L P + V+FV TD+L A+E RD   +NNP+EA+I++E+ + L++ G+   D+GIITPYNSQAS+I+ AI    VEIHTIDKYQGRDKDCIL
Subjt:  LSSSWLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCIL

Query:  VSFVRSSENPKSCTTSLLGDWHRINVAITRAK
        VSFVRS E P+S  +SLLGDWHRINVA+TRAK
Subjt:  VSFVRSSENPKSCTTSLLGDWHRINVAITRAK

AT2G03270.1 DNA-binding protein, putative

9.7e-25

25.46

Show/hide

Query:  DYVIL---STDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDEFMTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRF
        D V+L    +D G+  LA G++  L +  I V F +   +P    +T          R++K     ++  M+  L+QL       G LR    DLV   F
Subjt:  DYVIL---STDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDEFMTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRF

Query:  -DGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRGVSILLTSYTNTAVDNLLIKL---KSQPLLLGSDFA
         +     S+    S+    KNL+  Q+ AI K L++KD  L+ G PGTGKT+T+V  V   + RG  IL  + +N AVDN++ +L   K + + +G    
Subjt:  -DGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRGVSILLTSYTNTAVDNLLIKL---KSQPLLLGSDFA

Query:  YYLVFFSLDLDALLF-----------------VTGKMLFDRVEHTK---------CGRHQN---------------------------------------
                 LDA +                  + GK+L  + ++T+          G+ +                                        
Subjt:  YYLVFFSLDLDALLF-----------------VTGKMLFDRVEHTK---------CGRHQN---------------------------------------

Query:  ----------------------------EIGP-----EARENGLGISLFCRLSEAHPQAI-SALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLE
                                    ++ P     EA   GLG +LF RL++ +   I S L  QYRM   IM  S+  +Y +++   S   ++   +
Subjt:  ----------------------------EIGP-----EARENGLGISLFCRLSEAHPQAI-SALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLE

Query:  FSSLKLSSSWLKEALNPCKPVIFVCTDLLPAYETRD-HKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRL----AIKIASVEIHTIDK
          ++  SSS   EA      ++ V T      E +D  +   N  EA +     K L++ G++ +D+GIITPY +Q  ++R+      K+  +EI T+D 
Subjt:  FSSLKLSSSWLKEALNPCKPVIFVCTDLLPAYETRD-HKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRL----AIKIASVEIHTIDK

Query:  YQGRDKDCILVSFVRSSENPKSCTTSLLGDWHRINVAITRAK
        +QGR+K+ I++S VRS+   +      L D  R+NVA+TR++
Subjt:  YQGRDKDCILVSFVRSSENPKSCTTSLLGDWHRINVAITRAK

AT5G35970.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein

2.5e-12

28.91

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Query:  EARENGLGISLFCRLSEAHPQAISA-LQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSW-------LKEALNPCKPVIFVCTDLLP
        +A E GLG+SL  R +  H   ++  L +QYRM   I   ++  +YG  L+  S  +  + L   S  + ++W       L +   P   +   C + L 
Subjt:  EARENGLGISLFCRLSEAHPQAISA-LQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSW-------LKEALNPCKPVIFVCTDLLP

Query:  AYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIK----IASVEIHTIDKYQGRDKDCILVSFVRSSENPKSCTTSLLGDW
           T     + N  EA+I+      L+  G+    + + +PY +Q  ++R  +        VE+ TID +QGR+ D +++S VRS+          LGD 
Subjt:  AYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIK----IASVEIHTIDKYQGRDKDCILVSFVRSSENPKSCTTSLLGDW

Query:  HRINVAITRAK
         R+NVAITRA+
Subjt:  HRINVAITRAK

AT5G35970.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein

7.7e-06

28.26

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Query:  RIDKDEFMTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYI-WSEKNLNDD---------QRRAI-IKILTAKDYALILGMPG
        RID+   +        N   L L  +     +   + +VA  F  G   +      Y+ WSE  L+D+         QRRAI + +   +   ++ G PG
Subjt:  RIDKDEFMTSFAVMRFNLVQLFLQGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYI-WSEKNLNDD---------QRRAI-IKILTAKDYALILGMPG

Query:  TGKTSTMVHAVKALLMRGVSILLTSYTNTAVDNLLIKL
        TGKT  +   +   + +G  +L+T+ TN AVDN++ KL
Subjt:  TGKTSTMVHAVKALLMRGVSILLTSYTNTAVDNLLIKL

AT5G47010.1 RNA helicase, putative

1.4e-10

29.49

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Query:  EIGP-----EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSWLKEALNPCKPVIFVCTDLL
        ++GP     +A   GL  SLF RL     + I  LQ QYRM   + E  +   Y   L+ G        +E  +  +   W      P +P+ F      
Subjt:  EIGP-----EARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSSLKLSSSWLKEALNPCKPVIFVCTDLL

Query:  PAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQ-ASIIRLAIKIAS--------VEIHTIDKYQGRDKDCILVSFVRSSENPKSCTT
                  +N    AN+   VT   L  G+  + +G+ITPY  Q A I+    +  S        +E+ ++D +QGR+KD I++S VRS+E+      
Subjt:  PAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQ-ASIIRLAIKIAS--------VEIHTIDKYQGRDKDCILVSFVRSSENPKSCTT

Query:  SLLGDWHRINVAITRAK
          L D  R+NVA+TRA+
Subjt:  SLLGDWHRINVAITRAK

Sequences

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CDS sequence

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ATGCCTCCAAGGAAGAAGCCTAATTCTTCGTCCAAGAAGCTCAATTCTAATCAGCAATCGCAGCCTTCCAAGTTCGGCATCCAACACTTCTTCGAGCGCCACTCTCAAAA
TGTTGCGCACTCTCAGAAGCTCACTCCACGAACTTCCGATTCAAAGACTGATGTTTCTAACTCTGTGAATCGTGGAGATGATCGGAATGTGGAACGGCCAGATTCTAAGG
ACGCGGTTGCGGCGGCGGCGATGGCGACGGCTCAGAAGCCAGAGTTGCGGTTGCTTCCTGTGAGTGATGCGGTTTTGGCCTCTGAAAACCCTAAGTTGCCGCAGGGGAAT
GATGCTAGCAGTTCGTCTCTGAATACGACGCCTGAGAATTTGATTGCAGCTGTTGGAAATGCTGGTGATGACCATTCTAACGAGCTGTCTCCAGAATTTTCCAAGTCCGT
GTCCCTGAAGCGCTTCAAGTTCTCTCCCGGAATGTTAAAAATGGATCAGCTGATTAAGCAAAGTCAGGAAGAGGGGACTACAAATGATGAGATCACATGGAAGATATCTC
CAGTAAACGAAAGGCTTCAGGCTGTTTCAAAGCAATTGCCGGAAACTATAAGAGTTTTGGCGAACTCCTCAAGACTCAGCTCTTTGAGAATCCGACAGTGCTCACGAAAT
AAGGTATTAAATGTAGAGTTTAAATTGGGTCTCTTGACGCTAGGGTTTACTAACAATGATCCTTTACAGACTTCCCCTGTCCAGCCTGGGAGTTTTGAGCAGTTGAGTTC
ACCGAACCTGAAACCTTCTGAGGGATCGGTGGCTTCGTTAAATAAGAATGGATTGAAAAGGTTAAATCCTAAACATGATATGGAACCTAATGGAGTTGCGATTGATAGTT
TGAATGGCTCTAGAGTACATAACAGTCAGAGTCCATTTCGGACGCCCCCATCTTTGTCATACTCCGATAAGATTGCCAATGATGCTGCATCTGCGTGTAATGAAGCACCT
GATCACCCTATTTTAAGACCACACAAGAAGGCATTGCTTGAGCTTTTAGATCAGGTAGAAGATGTCATTTCTGTTGATACTGTCCCTTCTCCCATTGACTTGGAGGAGGA
TTCATCTGAATTACGAGGTAGGAATGGTAACAAATTGACGACCAAAGTTGATTCAGCTGCAATGCAAATTCCTAAAAAGATTCCAGACACAGTGATGAAGGCATCCCCTT
GTGATTTTCTTGTCTTGGAGGTAACTGAGAAATGTGAGCTAGCTGATACATCTGGTGTGAAACGCTCATATAAGGTTCTTCGCTTGCTAAATGAGCAAAGTGGAGAAGAG
CGGGCGGTATACCTTTGGGAAGACTGGTTTGACAGTATTATTGCACCTGGAGATACTGTGAATGTTATCGGTGAATTTGATGACCAAGGAAGATGTCATGTAGACCACGA
CAATAATTTTGTTATCCTACACCCCGATATACTTGTCTCTGGAACTCGGGTTGCTGGTCATTTGACCTGTCCAAGGAGGAGTGTTCTTGATGAGAGGTTGAAAAGTAACG
AACAGTCAATTTCAGCATTAATTGGTACTTTGCTGCACCAGGCTGGTCTTATGGAAGAGACACCAACTGTCGCCTTTTTGGAAGAAGTTTCGAGAATGGTGCTTCAGAAA
AGTATGGAAAATGTATATGCATGCGGAGCAAATGAAAAGGATATACGAAAAACTATGAATGAGGCAATTCCAAAAATTTTGCATTGGATCACCCTCTTCAAAGGCCCAAT
GGGTTTTAAAGCACCTACTATTGAGTTTAGATCTGATGATGGTCCCAGGAAAGTTAGTATATCAGAGGTAATTGATATTGAGGAGATGGCATGGGCTCCAAAATATGGTT
TGAAAGGAATTATTGATGCTTCTGTCAGGGTAAACGTAATGTCAAATTATAATAAATGTGCCGAGAATGTCATGCCTTTAGAGTTTAAAACTGGAAAGTTGCCAGCTGGC
CAGGCAATCCTCCATGGAACATCGTGCCCAAGTGATCTTGTACACACTACTTATGTCCGAGAGGTTCAAAGATCTGACTTGGTGGGGTTAATCATGCGTCGGAATGAACT
TGCAAATAACATCCTCAAGGCATCAACCGCACAACTACTCCCCCCTATGTTACAGATTCCAAGTGTGTGCAAAGGATGTCGCCATCTTGATGTTTGTACTGTCTATCATA
AGGTAAGCCCAAAGGCAATTCAATTTGAGGATCCTCTTCCTATTCTGCATTGTCTAAATATGCAAAATGGAAGCAAAGAGAGTAGCGGGCTTGGAGTTTTATTTGACACC
CATACAGATCATTTGAAAGCTTCTCATGGTATTTTCCTTCAGCATTGGGAAAGACTGGTTGATTTAGAGGCCAAGGAGACGGAGGTTGAAATTTGCAGTGCTTTCAAATG
TATCATATATAATGTTCAATTCACATGCTTATTTATGCCAATGCTAAGTCCAATCGGCTATAATGCTCATTTCTTTCAGCTTGTAAAGAGGGGAGTTTGGCACTCACATA
CTGCGGAGAAAAATCAAACATCTACTTGTCTTTCTTCTATTGTTCTTAGTACGTTGGATGACCAACCACATTGTACTTTTGAAAAGGACCACAGAATCAACTATCGCTTT
GTGTGTCAAGATTTGTCTTCTCAGAGTTTGAAAGATTCAAATGACGATAGTTCAAGCGCTGCTTCAATAAATGAAATGGACAGTTCACTTAGAGTTGGGGACTATGTGAT
ACTTAGTACAGATTCTGGGAATTTGACCTTAGCAAGTGGGATTATAACAGATCTGAGCAATCTCCATATCTGTGTTTCTTTTTCTAAGCGCCTACGTTTGCCTGGAAGCA
CTTCTTCTACAGAGGCACATGATCTTATGAAGCAGGTTTGGCGGATTGACAAGGATGAATTTATGACTTCTTTTGCCGTCATGAGGTTTAATCTTGTACAACTGTTTCTG
CAAGGTGAACAAAACGGCCATCTTAGAAAGTTGATCGTAGATCTTGTGGCTCCAAGATTTGACGGTGGATGCATATTCAGCCAGGATCCAGCAATATCTTACATTTGGTC
AGAGAAGAATTTAAATGATGACCAACGTCGAGCCATAATTAAGATACTTACAGCAAAGGATTATGCTCTGATTCTAGGAATGCCTGGAACAGGCAAGACATCCACAATGG
TTCATGCTGTGAAGGCATTGTTGATGAGAGGTGTATCCATTTTGCTCACGTCTTACACAAACACTGCTGTTGATAATTTACTTATCAAACTGAAATCTCAGCCATTGCTT
CTCGGGTCTGATTTTGCCTATTATCTAGTTTTCTTTTCTTTGGATCTGGATGCTCTTCTTTTTGTAACTGGTAAAATGCTCTTTGACAGAGTTGAACATACAAAGTGTGG
AAGACATCAGAATGAGATTGGACCAGAGGCTCGAGAAAATGGACTGGGGATAAGCTTGTTTTGTAGGCTTTCAGAAGCACATCCTCAAGCAATTTCCGCATTACAAAGCC
AGTATCGCATGTGCCGAGACATTATGGAATTATCGAATGCCTTGATATATGGAGACAGACTGCGTTGTGGTTCTGAAGAAACAGCGAATGCAAAGCTTGAATTTTCAAGT
TTAAAGTTATCTTCATCTTGGCTCAAGGAGGCTCTAAACCCATGCAAACCAGTTATCTTTGTTTGTACAGATTTATTACCTGCTTACGAGACGAGAGATCACAAGATTGT
GAACAACCCAATTGAAGCTAACATATTATCAGAGGTCACAAAGGGATTGCTTGATGGTGGGATTAAAGGGAATGATGTTGGCATTATCACTCCGTATAACTCCCAGGCAA
GCATCATTCGTCTAGCTATCAAGATAGCCTCTGTGGAGATACATACCATTGACAAATACCAGGGAAGAGATAAGGACTGCATATTGGTGTCCTTTGTTAGGTCCAGTGAA
AATCCGAAGAGCTGTACTACCTCACTTCTTGGAGACTGGCATAGAATTAATGTGGCCATTACACGTGCCAAGGTATTTTCCATTTCTGGAAATTCTAGTGATACTGCTTT
CTTTGGCAACTTGTTTTTAAATCCCCATCTGATGAAAGCAATTCTCGATCACAATTTTGCTGGACAAGTCACTTTATTGGTTGCACTTTGGACGGTCCAAAATCCAATGT
TCTGA

mRNA sequence

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Protein sequence

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MPPRKKPNSSSKKLNSNQQSQPSKFGIQHFFERHSQNVAHSQKLTPRTSDSKTDVSNSVNRGDDRNVERPDSKDAVAAAAMATAQKPELRLLPVSDAVLASENPKLPQGN
DASSSSLNTTPENLIAAVGNAGDDHSNELSPEFSKSVSLKRFKFSPGMLKMDQLIKQSQEEGTTNDEITWKISPVNERLQAVSKQLPETIRVLANSSRLSSLRIRQCSRN
KVLNVEFKLGLLTLGFTNNDPLQTSPVQPGSFEQLSSPNLKPSEGSVASLNKNGLKRLNPKHDMEPNGVAIDSLNGSRVHNSQSPFRTPPSLSYSDKIANDAASACNEAP
DHPILRPHKKALLELLDQVEDVISVDTVPSPIDLEEDSSELRGRNGNKLTTKVDSAAMQIPKKIPDTVMKASPCDFLVLEVTEKCELADTSGVKRSYKVLRLLNEQSGEE
RAVYLWEDWFDSIIAPGDTVNVIGEFDDQGRCHVDHDNNFVILHPDILVSGTRVAGHLTCPRRSVLDERLKSNEQSISALIGTLLHQAGLMEETPTVAFLEEVSRMVLQK
SMENVYACGANEKDIRKTMNEAIPKILHWITLFKGPMGFKAPTIEFRSDDGPRKVSISEVIDIEEMAWAPKYGLKGIIDASVRVNVMSNYNKCAENVMPLEFKTGKLPAG
QAILHGTSCPSDLVHTTYVREVQRSDLVGLIMRRNELANNILKASTAQLLPPMLQIPSVCKGCRHLDVCTVYHKVSPKAIQFEDPLPILHCLNMQNGSKESSGLGVLFDT
HTDHLKASHGIFLQHWERLVDLEAKETEVEICSAFKCIIYNVQFTCLFMPMLSPIGYNAHFFQLVKRGVWHSHTAEKNQTSTCLSSIVLSTLDDQPHCTFEKDHRINYRF
VCQDLSSQSLKDSNDDSSSAASINEMDSSLRVGDYVILSTDSGNLTLASGIITDLSNLHICVSFSKRLRLPGSTSSTEAHDLMKQVWRIDKDEFMTSFAVMRFNLVQLFL
QGEQNGHLRKLIVDLVAPRFDGGCIFSQDPAISYIWSEKNLNDDQRRAIIKILTAKDYALILGMPGTGKTSTMVHAVKALLMRGVSILLTSYTNTAVDNLLIKLKSQPLL
LGSDFAYYLVFFSLDLDALLFVTGKMLFDRVEHTKCGRHQNEIGPEARENGLGISLFCRLSEAHPQAISALQSQYRMCRDIMELSNALIYGDRLRCGSEETANAKLEFSS
LKLSSSWLKEALNPCKPVIFVCTDLLPAYETRDHKIVNNPIEANILSEVTKGLLDGGIKGNDVGIITPYNSQASIIRLAIKIASVEIHTIDKYQGRDKDCILVSFVRSSE
NPKSCTTSLLGDWHRINVAITRAKVFSISGNSSDTAFFGNLFLNPHLMKAILDHNFAGQVTLLVALWTVQNPMF

Spg032038 (gene) of Sponge gourd (cylindrica) v1 genome