CuGenDBv2

Gene ID	Spg033623
Organism	Luffa cylindrica (Sponge gourd (cylindrica) v1)
Description	mediator of RNA polymerase II transcription subunit 18
Genome location	scaffold13:39122052..39123875
RNA-Seq Expression	Spg033623
Synteny	Spg033623
Gene Ontology terms	GO:0006357 - regulation of transcription by RNA polymerase II (biological process) GO:0006369 - termination of RNA polymerase II transcription (biological process) GO:0016592 - mediator complex (cellular component) GO:0070847 - core mediator complex (cellular component) GO:0003712 - transcription coregulator activity (molecular function)
InterPro domains	IPR019095 - Mediator complex, subunit Med18

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0065265.1 mediator of RNA polymerase II transcription subunit 18 [Cucumis melo var. makuwa]

7.8e-104

95.65

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Query:  LQHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLD
        ++HVEALEILLQGICGVPRERLRLHEICLKSGP+LGAV SEVRILCDLEQAEP WTVKHIGGA+RGAGAEQLSV+VRTMVESKVSKNVLRLFY LGYKLD
Subjt:  LQHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLD

Query:  HELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS
        HELLRVGFAFRF+RGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS
Subjt:  HELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS

Query:  DGAGTTM
        DGAGTTM
Subjt:  DGAGTTM

XP_008444669.1 PREDICTED: mediator of RNA polymerase II transcription subunit 18 [Cucumis melo]

4.6e-104

96.6

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH
        QHVEALEILLQGICGVPRERLRLHEICLKSGP+LGAV SEVRILCDLEQAEP WTVKHIGGA+RGAGAEQLSV+VRTMVESKVSKNVLRLFY LGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRF+RGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        GAGTTM
Subjt:  GAGTTM

XP_011649597.2 mediator of RNA polymerase II transcription subunit 18 isoform X1 [Cucumis sativus]

9.2e-105

97.09

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH
        QHVEALEILLQGICGVPRERLRLHEICLKSGP+LGAV SEVRILCDLEQAEP WTVKHIGGA+RGAGAEQLSV+VRTMVESKVSKNVLRLFY LGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        GAGTTM
Subjt:  GAGTTM

XP_022144379.1 mediator of RNA polymerase II transcription subunit 18 [Momordica charantia]

8.3e-106

98.06

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH
        QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAV SEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSV+VRTMVESKVSKNVLRLFY LGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        GAGTTM
Subjt:  GAGTTM

XP_038885244.1 mediator of RNA polymerase II transcription subunit 18 [Benincasa hispida]

1.2e-104

96.6

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH
        QHVEALEILLQGICGVPRERLRLHEICLKSGP+LGAV SE+RILCDLEQAEP WTVKHIGGA+RGAGAEQLSV+VRTMVESKVSKNVLRLFY LGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        GAGTTM
Subjt:  GAGTTM

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LNJ4 Uncharacterized protein

1.1e-103

96.62

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH
        QHVEALEILLQGICGVPRERLRLHEICLKSGP+LGAV SEVRILCDLEQAEP WTVKHIGGA+RGAGAEQLSV+VRTMVESKVSKNVLRLFY LGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS-
        ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS 
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS-

Query:  DGAGTTM
        DGAGTTM
Subjt:  DGAGTTM

A0A1S3BBM1 mediator of RNA polymerase II transcription subunit 18

2.2e-104

96.6

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH
        QHVEALEILLQGICGVPRERLRLHEICLKSGP+LGAV SEVRILCDLEQAEP WTVKHIGGA+RGAGAEQLSV+VRTMVESKVSKNVLRLFY LGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRF+RGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        GAGTTM
Subjt:  GAGTTM

A0A5A7VHE6 Mediator of RNA polymerase II transcription subunit 18

3.8e-104

95.65

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Query:  LQHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLD
        ++HVEALEILLQGICGVPRERLRLHEICLKSGP+LGAV SEVRILCDLEQAEP WTVKHIGGA+RGAGAEQLSV+VRTMVESKVSKNVLRLFY LGYKLD
Subjt:  LQHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLD

Query:  HELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS
        HELLRVGFAFRF+RGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS
Subjt:  HELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS

Query:  DGAGTTM
        DGAGTTM
Subjt:  DGAGTTM

A0A6J1CS50 mediator of RNA polymerase II transcription subunit 18

4.0e-106

98.06

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH
        QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAV SEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSV+VRTMVESKVSKNVLRLFY LGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        GAGTTM
Subjt:  GAGTTM

A0A6J1GHW3 mediator of RNA polymerase II transcription subunit 18

6.4e-104

95.15

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH
        QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAV SEVRI+CDLEQ EP+WTVKHIGGAMRG+GAEQLSV+VRTMVESKVSKNVLRLFY LGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELLRVGF+FRFHRG HITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        GAGTTM
Subjt:  GAGTTM

SwissProt top hits

e value

%identity

Alignment

Q9SJZ6 Mediator of RNA polymerase II transcription subunit 18

5.4e-92

79.61

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Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH
        QHVEALEILLQG+CGV RERLR+HE+CL+SGPNLG V+SEVR+LCDL+Q EP WTVKH+GGAMRGAGA+Q+SV+VR M+ESKVSKN LR+FY LGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELL+VGFAF F R AHI+V+VSSVNKM K+H+ DEAVPVTPG+Q+V+VTAPATS+NYSEVA AVS+FCE+LAPL+HLSKP ISTGVVPTAAAAAASL+SD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        G GTT+
Subjt:  GAGTTM

Arabidopsis top hits

e value

%identity

Alignment

AT2G22370.1 unknown protein

3.9e-93

79.61

Show/hide

Query:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH
        QHVEALEILLQG+CGV RERLR+HE+CL+SGPNLG V+SEVR+LCDL+Q EP WTVKH+GGAMRGAGA+Q+SV+VR M+ESKVSKN LR+FY LGYKLDH
Subjt:  QHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYGLGYKLDH

Query:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD
        ELL+VGFAF F R AHI+V+VSSVNKM K+H+ DEAVPVTPG+Q+V+VTAPATS+NYSEVA AVS+FCE+LAPL+HLSKP ISTGVVPTAAAAAASL+SD
Subjt:  ELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSD

Query:  GAGTTM
        G GTT+
Subjt:  GAGTTM

Sequences

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CDS sequence

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ATGGTAGCGAGAAGTTTTGTGCTTTGGACTTCTATTGACAGTTTGATTCTGCAGCACGTTGAGGCGCTTGAGATACTTCTTCAAGGCATTTGCGGCGTTCCTAGAGAACG
GTTGAGGCTCCATGAAATATGCCTAAAAAGTGGACCTAACTTAGGTGCTGTAACTTCGGAGGTCCGGATCTTGTGTGACCTTGAGCAGGCTGAACCGGCATGGACGGTTA
AACATATTGGAGGGGCAATGAGAGGTGCAGGTGCTGAACAACTCTCTGTTATGGTTAGGACAATGGTAGAAAGCAAAGTTAGCAAGAATGTGCTTCGCCTTTTTTATGGA
CTTGGCTACAAGTTAGACCACGAGCTGCTGAGAGTCGGTTTTGCTTTCCGGTTCCACCGCGGTGCTCATATAACTGTGACAGTTTCATCCGTTAATAAGATGTTAAAGCT
ACATTCTACGGATGAGGCTGTACCTGTAACACCTGGTATACAGCTAGTTGAAGTGACAGCTCCAGCAACCTCTGATAACTACTCTGAAGTAGCCGGTGCAGTGTCGACTT
TCTGCGAATATCTTGCACCGCTGCTGCATTTGTCAAAACCGGGAATATCCACAGGTGTTGTTCCTACTGCTGCTGCCGCTGCAGCATCTCTGCTGTCTGATGGTGCAGGA
ACAACAATGTAG

mRNA sequence

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Protein sequence

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MVARSFVLWTSIDSLILQHVEALEILLQGICGVPRERLRLHEICLKSGPNLGAVTSEVRILCDLEQAEPAWTVKHIGGAMRGAGAEQLSVMVRTMVESKVSKNVLRLFYG
LGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAG
TTM

Spg033623 (gene) of Sponge gourd (cylindrica) v1 genome