CuGenDBv2

Gene ID	Spg036051
Organism	Luffa cylindrica (Sponge gourd (cylindrica) v1)
Description	DNA polymerase epsilon catalytic subunit
Genome location	scaffold5:41701316..41702200
RNA-Seq Expression	Spg036051
Synteny	Spg036051
Gene Ontology terms	GO:0006260 - DNA replication (biological process) GO:0006281 - DNA repair (biological process) GO:0071897 - DNA biosynthetic process (biological process) GO:0008622 - epsilon DNA polymerase complex (cellular component) GO:0000166 - nucleotide binding (molecular function) GO:0003677 - DNA binding (molecular function) GO:0003887 - DNA-directed DNA polymerase activity (molecular function) GO:0008270 - zinc ion binding (molecular function) GO:0051539 - 4 iron, 4 sulfur cluster binding (molecular function)
InterPro domains	NA

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

XP_022153061.1 DNA polymerase epsilon catalytic subunit A-like isoform X1 [Momordica charantia]

1.5e-46

74.81

Show/hide

Query:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ
        SV Q +FNGGGCEPSS LH E++ KNVDY G LEMKK KWKDTLDKRK QRL++LRT LP N V+ ELN  MN+KE    + VGS FKRHE SITRCHWQ
Subjt:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ

Query:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP
        ILQLVHSSQS Q+FA AVVEGVMLKIPITVP
Subjt:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP

XP_022153062.1 DNA polymerase epsilon catalytic subunit A-like isoform X2 [Momordica charantia]

1.5e-46

74.81

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Query:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ
        SV Q +FNGGGCEPSS LH E++ KNVDY G LEMKK KWKDTLDKRK QRL++LRT LP N V+ ELN  MN+KE    + VGS FKRHE SITRCHWQ
Subjt:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ

Query:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP
        ILQLVHSSQS Q+FA AVVEGVMLKIPITVP
Subjt:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP

XP_038901114.1 DNA polymerase epsilon catalytic subunit A-like isoform X1 [Benincasa hispida]

2.4e-44

73.28

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Query:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ
        S MQ++FN GGCEPSS LH E+I KNVDY G LEMKK KWKDTLDKRK QRL+ LRTPL  N V +ELN   N+KEA+  T VGS FKRHE S+TRCHWQ
Subjt:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ

Query:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP
        ILQLVHS+QS QYFA AVV GVMLKIPI VP
Subjt:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP

XP_038901115.1 DNA polymerase epsilon catalytic subunit A-like isoform X2 [Benincasa hispida]

2.4e-44

73.28

Show/hide

Query:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ
        S MQ++FN GGCEPSS LH E+I KNVDY G LEMKK KWKDTLDKRK QRL+ LRTPL  N V +ELN   N+KEA+  T VGS FKRHE S+TRCHWQ
Subjt:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ

Query:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP
        ILQLVHS+QS QYFA AVV GVMLKIPI VP
Subjt:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP

XP_038901116.1 DNA polymerase epsilon catalytic subunit A-like isoform X3 [Benincasa hispida]

2.4e-44

73.28

Show/hide

Query:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ
        S MQ++FN GGCEPSS LH E+I KNVDY G LEMKK KWKDTLDKRK QRL+ LRTPL  N V +ELN   N+KEA+  T VGS FKRHE S+TRCHWQ
Subjt:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ

Query:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP
        ILQLVHS+QS QYFA AVV GVMLKIPI VP
Subjt:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KDM5 DNA polymerase epsilon catalytic subunit

5.9e-41

68.7

Show/hide

Query:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ
        S MQ++FN GG EPSS +  E+I KNVDY G LE+KK KWKDTLD+RK QRL++ RTPL  N V++ELN   N+K+A   T VGS FKRHE S+TRCHWQ
Subjt:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ

Query:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP
        ILQLVHS QS QYFA AVVEGVMLKIPI VP
Subjt:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP

A0A1S3C879 DNA polymerase epsilon catalytic subunit

1.6e-41

69.47

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Query:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ
        S MQD+FN GG EPSS L  E+I KNVDY G LE+KK KWKDTLD+RK QRL+  RTPL  N +++ELN   N+K+    T VGS FKRHE S+TRCHWQ
Subjt:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ

Query:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP
        ILQLVHSSQS QYFA AVVEGVMLKIPI VP
Subjt:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP

A0A1S4E210 DNA polymerase epsilon catalytic subunit

1.6e-41

69.47

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Query:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ
        S MQD+FN GG EPSS L  E+I KNVDY G LE+KK KWKDTLD+RK QRL+  RTPL  N +++ELN   N+K+    T VGS FKRHE S+TRCHWQ
Subjt:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ

Query:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP
        ILQLVHSSQS QYFA AVVEGVMLKIPI VP
Subjt:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP

A0A6J1DHX7 DNA polymerase epsilon catalytic subunit

7.2e-47

74.81

Show/hide

Query:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ
        SV Q +FNGGGCEPSS LH E++ KNVDY G LEMKK KWKDTLDKRK QRL++LRT LP N V+ ELN  MN+KE    + VGS FKRHE SITRCHWQ
Subjt:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ

Query:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP
        ILQLVHSSQS Q+FA AVVEGVMLKIPITVP
Subjt:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP

A0A6J1DJK0 DNA polymerase epsilon catalytic subunit

7.2e-47

74.81

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Query:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ
        SV Q +FNGGGCEPSS LH E++ KNVDY G LEMKK KWKDTLDKRK QRL++LRT LP N V+ ELN  MN+KE    + VGS FKRHE SITRCHWQ
Subjt:  SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQ

Query:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP
        ILQLVHSSQS Q+FA AVVEGVMLKIPITVP
Subjt:  ILQLVHSSQSDQYFASAVVEGVMLKIPITVP

SwissProt top hits

e value

%identity

Alignment

F4HW04 DNA polymerase epsilon catalytic subunit A

1.7e-21

49.12

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Query:  LHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQILQLVHSSQSDQYFASA
        + F++I K+V+YQG LE+KK KWK TL+K+K +RL DLR+       +Q     +N K       VGS F+R E ++T  HWQI+QLV S QS Q+FA  
Subjt:  LHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQILQLVHSSQSDQYFASA

Query:  VVEGVMLKIPITVP
        VVEG+MLKIP+++P
Subjt:  VVEGVMLKIPITVP

F4IFN6 DNA polymerase epsilon catalytic subunit B

1.5e-17

45.61

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Query:  LHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQILQLVHSSQSDQYFASA
        +  +++ KNVDYQG LE++K KWK TL  +K +R         L G   E N  +N K       VGS F+R E ++T  + QI+QLV S QS Q+FA  
Subjt:  LHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQILQLVHSSQSDQYFASA

Query:  VVEGVMLKIPITVP
        VVEG+MLKIP+T+P
Subjt:  VVEGVMLKIPITVP

Arabidopsis top hits

e value

%identity

Alignment

AT1G08260.1 DNA polymerase epsilon catalytic subunit

1.2e-22

49.12

Show/hide

Query:  LHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQILQLVHSSQSDQYFASA
        + F++I K+V+YQG LE+KK KWK TL+K+K +RL DLR+       +Q     +N K       VGS F+R E ++T  HWQI+QLV S QS Q+FA  
Subjt:  LHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQILQLVHSSQSDQYFASA

Query:  VVEGVMLKIPITVP
        VVEG+MLKIP+++P
Subjt:  VVEGVMLKIPITVP

AT2G27120.1 DNA polymerase epsilon catalytic subunit

1.1e-18

45.61

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Query:  LHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQILQLVHSSQSDQYFASA
        +  +++ KNVDYQG LE++K KWK TL  +K +R         L G   E N  +N K       VGS F+R E ++T  + QI+QLV S QS Q+FA  
Subjt:  LHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQILQLVHSSQSDQYFASA

Query:  VVEGVMLKIPITVP
        VVEG+MLKIP+T+P
Subjt:  VVEGVMLKIPITVP

Sequences

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CDS sequence

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TCCGTGATGCAGGATGATTTTAATGGTGGAGGATGTGAGCCTTCTTCATCATTGCATTTTGAAGACATTGTCAAAAATGTGGATTACCAAGGATGTCTTGAAATGAAGAA
GCTAAAGTGGAAGGATACTTTGGACAAGAGGAAGAACCAAAGATTGATAGATTTAAGAACTCCACTTCCTCTTAATGGTGTTTCACAGGAGTTAAATTGTGGTATGAATG
ATAAAGAGGCTGCTGCAATAACATGCGTTGGTTCATCTTTCAAGAGGCATGAAAATTCTATAACACGCTGCCATTGGCAAATTTTACAGCTTGTTCATAGTTCACAGAGT
GACCAATATTTTGCTTCGGCTGTTGTTGAAGGAGTTATGCTAAAGATTCCTATTACGGTTCCTTAG

mRNA sequence

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Protein sequence

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SVMQDDFNGGGCEPSSSLHFEDIVKNVDYQGCLEMKKLKWKDTLDKRKNQRLIDLRTPLPLNGVSQELNCGMNDKEAAAITCVGSSFKRHENSITRCHWQILQLVHSSQS
DQYFASAVVEGVMLKIPITVP

Spg036051 (gene) of Sponge gourd (cylindrica) v1 genome