CuGenDBv2

Gene ID	Spg036368
Organism	Luffa cylindrica (Sponge gourd (cylindrica) v1)
Description	dCTP pyrophosphatase 1
Genome location	scaffold5:47926503..47927471
RNA-Seq Expression	Spg036368
Synteny	Spg036368
Gene Ontology terms	GO:0006253 - dCTP catabolic process (biological process) GO:0042262 - DNA protection (biological process) GO:0005829 - cytosol (cellular component) GO:0000287 - magnesium ion binding (molecular function) GO:0047840 - dCTP diphosphatase activity (molecular function)
InterPro domains	IPR025984 - dCTP pyrophosphatase 1

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6607469.1 dCTP pyrophosphatase 1, partial [Cucurbita argyrosperma subsp. sororia]

5.4e-52

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Query:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA
        MEKT    NKDV LRELSERVAEFARVRGW+K+HSPRNLLLALVGEVGE+SEIFQWKGEVARGLPNWSAADKE L EELSDVLLYLVRLADVCG+DLGRA
Subjt:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA

Query:  ALSKILKNATKYPLIPHQQQ
        ALSKILKNATKYPL PHQQQ
Subjt:  ALSKILKNATKYPLIPHQQQ

XP_022137081.1 dCTP pyrophosphatase 1-like [Momordica charantia]

1.5e-49

85.83

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Query:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA
        MEKT +Y + DVSL EL +RVAEFA  RGW+K H+PRNLLLALVGEVGELSEIFQWKGEVARGLPNWSA DKEHLEEELSDVLLYLVRLADVCGLDLGRA
Subjt:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA

Query:  ALSKILKNATKYPLIPHQQQ
        ALSKILKNA KYPLIPHQ++
Subjt:  ALSKILKNATKYPLIPHQQQ

XP_022948897.1 dCTP pyrophosphatase 1-like [Cucurbita moschata]

1.3e-50

87.5

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Query:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA
        MEK     NKDV LRELSERVAEFARVRGW+K+HS RNLLLALVGEVGE+SEIFQWKGEVARGLPNWSAADKE L EELSDVLLYLVRLADVC +DLGRA
Subjt:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA

Query:  ALSKILKNATKYPLIPHQQQ
        ALSKILKNATKYPL PHQQQ
Subjt:  ALSKILKNATKYPLIPHQQQ

XP_022998186.1 dCTP pyrophosphatase 1-like [Cucurbita maxima]

1.8e-52

86.99

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Query:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA
        M+K     NKDV L+ELSERVAEFARVRGW+K+HSPRNLLLALVGEVGE++EIFQWKGEVARGLPNWSAADKEHL EELSDVLLYLVRLADVCG+DLGRA
Subjt:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA

Query:  ALSKILKNATKYPLIPHQQQIQP
        ALSKILKNATKYPL PH QQIQP
Subjt:  ALSKILKNATKYPLIPHQQQIQP

XP_038895217.1 dCTP pyrophosphatase 1-like [Benincasa hispida]

1.6e-48

81.45

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Query:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA
        MEK    N ++VSLRELSERVAEF RVRGW+K+H+PRNLLLALVGEVGE+SEIFQWKGEV +GLP+WSAADKEHLE+ELSDV LYL+RLADVCGLDL +A
Subjt:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA

Query:  ALSKILKNATKYPL-IPHQQQIQP
        ALSKILKNA+KYPL  PHQQQIQP
Subjt:  ALSKILKNATKYPL-IPHQQQIQP

TrEMBL top hits

e value

%identity

Alignment

A0A1R3HEG6 dCTP pyrophosphatase 1

3.3e-47

80.33

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Query:  MEKTSSYNN---KDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDL
        MEK+    N   KDVSL+EL +R+AEFA VRGWEK+HSPRNLLLALVGEVGELSEIFQWKGEVA+GLPNWSA DKEHLE+ELSDVLLYLV+LADVCGLDL
Subjt:  MEKTSSYNN---KDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDL

Query:  GRAALSKILKNATKYPLIPHQQ
        GRAALSKILKNA KYP++ +Q+
Subjt:  GRAALSKILKNATKYPLIPHQQ

A0A1R3KCG6 dCTP pyrophosphatase 1

3.3e-47

80.33

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Query:  MEKTSSYNN---KDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDL
        MEK+    N   KDVSL+EL +R+AEFA VRGWEK+HSPRNLLLALVGEVGELSEIFQWKGEVA+GLPNWSA DKEHLE+ELSDVLLYLV+LADVCGLDL
Subjt:  MEKTSSYNN---KDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDL

Query:  GRAALSKILKNATKYPLIPHQQ
        GRAALSKILKNA KYP++ +Q+
Subjt:  GRAALSKILKNATKYPLIPHQQ

A0A6J1C5G1 dCTP pyrophosphatase 1

7.1e-50

85.83

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Query:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA
        MEKT +Y + DVSL EL +RVAEFA  RGW+K H+PRNLLLALVGEVGELSEIFQWKGEVARGLPNWSA DKEHLEEELSDVLLYLVRLADVCGLDLGRA
Subjt:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA

Query:  ALSKILKNATKYPLIPHQQQ
        ALSKILKNA KYPLIPHQ++
Subjt:  ALSKILKNATKYPLIPHQQQ

A0A6J1GAI3 dCTP pyrophosphatase 1

6.4e-51

87.5

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Query:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA
        MEK     NKDV LRELSERVAEFARVRGW+K+HS RNLLLALVGEVGE+SEIFQWKGEVARGLPNWSAADKE L EELSDVLLYLVRLADVC +DLGRA
Subjt:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA

Query:  ALSKILKNATKYPLIPHQQQ
        ALSKILKNATKYPL PHQQQ
Subjt:  ALSKILKNATKYPLIPHQQQ

A0A6J1K9K2 dCTP pyrophosphatase 1

8.9e-53

86.99

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Query:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA
        M+K     NKDV L+ELSERVAEFARVRGW+K+HSPRNLLLALVGEVGE++EIFQWKGEVARGLPNWSAADKEHL EELSDVLLYLVRLADVCG+DLGRA
Subjt:  MEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRA

Query:  ALSKILKNATKYPLIPHQQQIQP
        ALSKILKNATKYPL PH QQIQP
Subjt:  ALSKILKNATKYPLIPHQQQIQP

SwissProt top hits

e value

%identity

Alignment

Q32KY6 dCTP pyrophosphatase 1

4.9e-24

47.9

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Query:  RWEAMEKTSSYN-NKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGL
        R E+   T  ++ + + +L ++    AEFA  R WE+FH PRNLLLALVGEVGEL+E+FQWK +   G   WS  ++  L+EELSD+L+YLV LA  C +
Subjt:  RWEAMEKTSSYN-NKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGL

Query:  DLGRAALSKILKNATKYPL
        DL +A L K+  N  +YP+
Subjt:  DLGRAALSKILKNATKYPL

Q91VC0 dCTP pyrophosphatase 1

7.6e-25

53.92

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Query:  SLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKNATKY
        +L ++    AEFA  R WE+FH PRNLLLALVGEVGEL+E+FQWK +   G   W   ++  L+EELSDVL+YLV LA  C +DL RA +SK+  N  +Y
Subjt:  SLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKNATKY

Query:  PL
        P+
Subjt:  PL

Q9H773 dCTP pyrophosphatase 1

4.9e-24

55.45

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Query:  SLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKNATKY
        +L ++    AEFA  R WE+FH PRNLLLALVGEVGEL+E+FQWK +   G   WS  ++  L+EELSDVL+YLV LA  C +DL  A LSK+  N  +Y
Subjt:  SLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKNATKY

Query:  P
        P
Subjt:  P

Q9QY93 dCTP pyrophosphatase 1

2.9e-24

52.94

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Query:  SLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKNATKY
        +L ++    AEFA  R WE+FH PRNLLLALVGEVGEL+E+FQWK +   G   W   ++  L+EELSDVL+YLV LA  C +DL +A +SK+  N  +Y
Subjt:  SLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKNATKY

Query:  PL
        P+
Subjt:  PL

Arabidopsis top hits

e value

%identity

Alignment

AT3G25400.1 CONTAINS InterPro DOMAIN/s: NTP Pyrophosphohydrolase MazG-related, RS21-C6 (InterPro:IPR011394), EAR (InterPro:IPR009039), NTP pyrophosphohydrolase MazG, putative catalytic core (InterPro:IPR004518); Has 1123 Blast hits to 1121 proteins in 452 species: Archae - 22; Bacteria - 753; Metazoa - 81; Fungi - 3; Plants - 83; Viruses - 0; Other Eukaryotes - 181 (source: NCBI BLink).

5.5e-39

71.84

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Query:  VSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKNATK
        VSL+ LS+++ +FA+ R WEK+HSPRNLLLA+VGEVGELSEIFQWKGEVARG P+W   +K HL EELSDVLLYLVRL+D CG+DLG+AAL KI  NA K
Subjt:  VSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAALSKILKNATK

Query:  YPL
        YP+
Subjt:  YPL

Sequences

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CDS sequence

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ACCATAGAAAGAGAGAGATGGGAGGCAATGGAGAAGACAAGTAGTTATAACAACAAAGATGTTTCTCTTCGAGAACTTAGTGAAAGAGTGGCAGAATTTGCTCGAGTTAG
AGGTTGGGAAAAGTTTCACAGCCCTAGAAATCTCCTTCTCGCCCTAGTCGGAGAAGTCGGGGAGCTGTCGGAGATATTCCAATGGAAAGGGGAAGTGGCGAGGGGGCTGC
CGAACTGGTCCGCCGCCGACAAGGAGCATTTGGAAGAGGAGCTGTCGGACGTGTTGCTCTATTTGGTTCGGCTTGCAGATGTGTGTGGGCTTGATCTAGGTCGAGCTGCC
CTTTCTAAGATCCTTAAAAATGCCACTAAGTACCCTCTCATTCCTCACCAACAACAAATTCAACCCTAA

mRNA sequence

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Protein sequence

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TIERERWEAMEKTSSYNNKDVSLRELSERVAEFARVRGWEKFHSPRNLLLALVGEVGELSEIFQWKGEVARGLPNWSAADKEHLEEELSDVLLYLVRLADVCGLDLGRAA
LSKILKNATKYPLIPHQQQIQP

Spg036368 (gene) of Sponge gourd (cylindrica) v1 genome