CuGenDBv2

Gene ID	Spg037630
Organism	Luffa cylindrica (Sponge gourd (cylindrica) v1)
Description	Flap endonuclease 1
Genome location	scaffold2:50680864..50684570
RNA-Seq Expression	Spg037630
Synteny	Spg037630
Gene Ontology terms	GO:0006974 - cellular response to DNA damage stimulus (biological process) GO:0044260 - cellular macromolecule metabolic process (biological process) GO:0090304 - nucleic acid metabolic process (biological process) GO:0005634 - nucleus (cellular component) GO:0004519 - endonuclease activity (molecular function) GO:0046872 - metal ion binding (molecular function)
InterPro domains	IPR006084 - XPG/Rad2 endonuclease IPR036279 - 5'-3' exonuclease, C-terminal domain superfamily

Homology

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GenBank top hits

e value

%identity

Alignment

XP_022159615.1 flap endonuclease 1 isoform X2 [Momordica charantia]

1.1e-38

60.84

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Query:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD
        L IL+    C    GIGGQTALKLIRQHGSIE ILENINKER                             YQIP+DWPYQEAR+LFKEPLVCTDEEQLD
Subjt:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD

Query:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK
        IKWTTPDEE                   AVEKIKAAKNKSSQGRLESFFKPVTNPSV IKRK  S+
Subjt:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK

XP_022969706.1 flap endonuclease 1 isoform X2 [Cucurbita maxima]

8.5e-39

60.24

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Query:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD
        L IL+    C    GIGGQTALKLIRQHGSIENILENINKER                             YQIP+DWP+QEAR+LFKEPLVCTDEEQLD
Subjt:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD

Query:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK
        IKWTTPDEE                   AVEKIKAAKNKSSQGR+ESFFKPVTNPSVS KRK  S+
Subjt:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK

XP_031740577.1 flap endonuclease 1 [Cucumis sativus]

1.9e-38

60.24

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Query:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD
        L IL+    C    GIGG TALKLIRQHGSIE+ILENINKER                             YQIPDDWPY+EAR+LFKEPLVCTDEEQLD
Subjt:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD

Query:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK
        IKWTTPDEE                   AVEKIKAAKNKSSQGR+ESFFKPVTNPSVSIKRK  S+
Subjt:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK

XP_038879461.1 flap endonuclease 1 isoform X1 [Benincasa hispida]

2.9e-39

62.35

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Query:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD
        L IL+    C    GIGGQTALKLIRQHGSIE ILENINKER                             YQIPDDWPYQEAR+LFKEPLVCTDEEQLD
Subjt:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD

Query:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRK
        IKWTTPDEE                   AVEKIKAAKNKSSQGR+ESFFKPVTNPSVSIKRK
Subjt:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRK

XP_038879462.1 flap endonuclease 1 isoform X2 [Benincasa hispida]

1.3e-39

61.45

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Query:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD
        L IL+    C    GIGGQTALKLIRQHGSIE ILENINKER                             YQIPDDWPYQEAR+LFKEPLVCTDEEQLD
Subjt:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD

Query:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK
        IKWTTPDEE                   AVEKIKAAKNKSSQGR+ESFFKPVTNPSVSIKRK  S+
Subjt:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LWA2 Flap endonuclease 1

9.2e-39

60.24

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Query:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD
        L IL+    C    GIGG TALKLIRQHGSIE+ILENINKER                             YQIPDDWPY+EAR+LFKEPLVCTDEEQLD
Subjt:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD

Query:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK
        IKWTTPDEE                   AVEKIKAAKNKSSQGR+ESFFKPVTNPSVSIKRK  S+
Subjt:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK

A0A6J1DZ85 Flap endonuclease 1

5.4e-39

60.84

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Query:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD
        L IL+    C    GIGGQTALKLIRQHGSIE ILENINKER                             YQIP+DWPYQEAR+LFKEPLVCTDEEQLD
Subjt:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD

Query:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK
        IKWTTPDEE                   AVEKIKAAKNKSSQGRLESFFKPVTNPSV IKRK  S+
Subjt:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK

A0A6J1DZA7 Flap endonuclease 1

1.2e-38

61.73

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Query:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD
        L IL+    C    GIGGQTALKLIRQHGSIE ILENINKER                             YQIP+DWPYQEAR+LFKEPLVCTDEEQLD
Subjt:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD

Query:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRK
        IKWTTPDEE                   AVEKIKAAKNKSSQGRLESFFKPVTNPSV IKRK
Subjt:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRK

A0A6J1HYJ9 Flap endonuclease 1

4.1e-39

60.24

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Query:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD
        L IL+    C    GIGGQTALKLIRQHGSIENILENINKER                             YQIP+DWP+QEAR+LFKEPLVCTDEEQLD
Subjt:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD

Query:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK
        IKWTTPDEE                   AVEKIKAAKNKSSQGR+ESFFKPVTNPSVS KRK  S+
Subjt:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK

A0A6J1I0P7 Flap endonuclease 1

9.2e-39

61.11

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Query:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD
        L IL+    C    GIGGQTALKLIRQHGSIENILENINKER                             YQIP+DWP+QEAR+LFKEPLVCTDEEQLD
Subjt:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD

Query:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRK
        IKWTTPDEE                   AVEKIKAAKNKSSQGR+ESFFKPVTNPSVS KRK
Subjt:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRK

SwissProt top hits

e value

%identity

Alignment

B8AW67 Flap endonuclease 1-A

4.4e-30

50.6

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Query:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD
        L IL+    C    GIGGQTALKLIRQHGSIE+ILENINK+R                             YQIP+DWPYQEAR+LFKEP V  D  +L 
Subjt:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD

Query:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK
         KW  PDEE                   A+EKIK AKNKSSQGRLESFFKPV + SV +KRK+ S+
Subjt:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK

C5YUK3 Flap endonuclease 1-A

5.7e-30

50.62

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Query:  CVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEE
        C    GIGGQTALKLIRQHGSIE+ILEN+NK+R                             YQIP+DWPYQEAR+LFKEP V  D  +L  KWT PDEE
Subjt:  CVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLDIKWTTPDEE

Query:  -------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSKSVS
                           A+EKIK+AKNKSSQGRLESFFKPV   S  +KRK  S   S
Subjt:  -------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSKSVS

C6TEX6 Flap endonuclease 1

1.2e-35

54.94

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Query:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD
        L IL+    C    GIGG TALKLIRQHGSIENI EN+NKER                             YQIPD+WPYQEAR+LFKEPLV TDE++LD
Subjt:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD

Query:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRK
        IKW++PDEE                   A+EKIK AKNKSSQGRLESFFKP  NPSV IKRK
Subjt:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRK

O65251 Flap endonuclease 1

7.0e-36

53.85

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Query:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD
        L IL+    C    GIGGQTALKLIRQHGSIE ILEN+NKER                             YQIP++WPY EARKLFKEP V TDEEQLD
Subjt:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD

Query:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSKSVS
        IKWT+PDEE                   A+EKIK AKNKSSQGRLESFFKPV N SV  KRK + +S +
Subjt:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSKSVS

Q9SXQ6 Flap endonuclease 1-A

4.4e-30

50.6

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Query:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD
        L IL+    C    GIGGQTALKLIRQHGSIE+ILENINK+R                             YQIP+DWPYQEAR+LFKEP V  D  +L 
Subjt:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD

Query:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK
         KW  PDEE                   A+EKIK AKNKSSQGRLESFFKPV + SV +KRK+ S+
Subjt:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSK

Arabidopsis top hits

e value

%identity

Alignment

AT5G26680.1 5'-3' exonuclease family protein

1.9e-36

55.56

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Query:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD
        L IL+    C    GIGGQTALKLIRQHGSIE ILEN+NKER                             YQIP++WPY EARKLFKEP V TDEEQLD
Subjt:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD

Query:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRK
        IKWT+PDEE                   A+EKIK AKNKSSQGRLESFFKPV N SV  KRK
Subjt:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRK

AT5G26680.2 5'-3' exonuclease family protein

5.0e-37

53.85

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Query:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD
        L IL+    C    GIGGQTALKLIRQHGSIE ILEN+NKER                             YQIP++WPY EARKLFKEP V TDEEQLD
Subjt:  LYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD

Query:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSKSVS
        IKWT+PDEE                   A+EKIK AKNKSSQGRLESFFKPV N SV  KRK + +S +
Subjt:  IKWTTPDEE-------------------AVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSKSVS

Sequences

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CDS sequence

Show/hide CDS sequence

ATGTTCAAATTTTGTTGCGCTGTTCCAGTTTTATATATTCTGAATGTAGAGCCCTTATGCGTTTACTCCACAGGTATAGGGGGGCAGACTGCTCTAAAGCTTATCCGTCA
ACATGGGTCTATAGAAAACATATTAGAGAACATAAATAAAGAAAGGGAGAATGACATGCTGGAAGCACCATTTGAGGAAGAGGAAATCTATAAAGGTGTCATGAATCTTG
GTAATCTTAAATCTCATGGATGGTACCAAATTCCAGATGATTGGCCTTATCAAGAGGCACGAAAGCTTTTTAAAGAACCACTAGTATGTACTGACGAAGAGCAACTTGAT
ATTAAGTGGACTACTCCGGATGAAGAAGCAGTAGAAAAAATTAAAGCAGCCAAGAACAAGTCATCACAGGGCCGGTTGGAGTCATTTTTCAAGCCCGTAACTAATCCTTC
AGTATCCATTAAGCGAAAGAACCTGTCCAAGAGTGTTTCCTTGCCTCTTTCTGTCTAA

mRNA sequence

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Protein sequence

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MFKFCCAVPVLYILNVEPLCVYSTGIGGQTALKLIRQHGSIENILENINKERENDMLEAPFEEEEIYKGVMNLGNLKSHGWYQIPDDWPYQEARKLFKEPLVCTDEEQLD
IKWTTPDEEAVEKIKAAKNKSSQGRLESFFKPVTNPSVSIKRKNLSKSVSLPLSV

Spg037630 (gene) of Sponge gourd (cylindrica) v1 genome