CuGenDBv2

Gene ID	Spg038958
Organism	Luffa cylindrica (Sponge gourd (cylindrica) v1)
Description	DNA topoisomerase 2
Genome location	scaffold12:5380325..5387337
RNA-Seq Expression	Spg038958
Synteny	Spg038958
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0043231 - intracellular membrane-bounded organelle (cellular component) GO:0003677 - DNA binding (molecular function) GO:0046872 - metal ion binding (molecular function) GO:0005524 - ATP binding (molecular function) GO:0003918 - DNA topoisomerase type II (ATP-hydrolyzing) activity (molecular function)
InterPro domains	IPR013506 - DNA topoisomerase, type IIA, subunit B, domain 2 IPR036890 - Histidine kinase/HSP90-like ATPase superfamily IPR034157 - DNA topoisomerase 2, TOPRIM domain IPR031660 - C-terminal associated domain of TOPRIM IPR020568 - Ribosomal protein S5 domain 2-type fold IPR018522 - DNA topoisomerase, type IIA, conserved site IPR014721 - Ribosomal protein S5 domain 2-type fold, subgroup IPR013760 - DNA topoisomerase, type IIA-like domain superfamily IPR013759 - DNA topoisomerase, type IIA, subunit B, C-terminal IPR013758 - DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta IPR013757 - Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily IPR006171 - TOPRIM domain IPR003594 - Histidine kinase/HSP90-like ATPase IPR002205 - DNA topoisomerase, type IIA, subunit A/C-terminal IPR001241 - DNA topoisomerase, type IIA IPR001154 - DNA topoisomerase II, eukaryotic-type

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAG7018075.1 DNA topoisomerase 2 [Cucurbita argyrosperma subsp. argyrosperma]

0.0e+00

88.4

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNAANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL
        S+KVVID EQN ISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQ           
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL

Query:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
                                               VFSDNMGKKSEPIITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
Subjt:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK

Query:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK
        TVKVELNGQRVPVKSFQDYVD YLKSA+AF TEPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK
Subjt:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK

Query:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS
        AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFG ACEL+P+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS
Subjt:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS

Query:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN
        EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI ENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLIN
Subjt:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN

Query:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA
        FIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELA
Subjt:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA

Query:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
        FSKKKIEERKNWLRQFE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
Subjt:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL

Query:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI
        ASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI
Subjt:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI

Query:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP
        PNYNPRDIIRNVRR+L+GE M+PMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRI ELPVR+WTNDYK+FLDSVTRV+ +NDKDKEKAAKDP
Subjt:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP

Query:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV
        FIEQADHHSDDK VSIDVHLTEENMILAMQEGLKKKFKLT T+STSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKV
Subjt:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV

Query:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVE
        RFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNET+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE
Subjt:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVE

Query:  DLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTAEVASNAVVKPKGKAA
        +LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQRIK NND+KP+ISRNAPKAPRNSKKTSNSE +TESMD TTSSSTT EVA+N VVKPKGK A
Subjt:  DLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTAEVASNAVVKPKGKAA

Query:  APRKAPAKK-GKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNS
        APRKAPAKK GKAAV+   D+DDDDEVLELKDRLAAYK+ESSP+ SE               VSAMETEVP+VQ  AKKKEPSKRA AKKKTTAKSAQ S
Subjt:  APRKAPAKK-GKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNS

Query:  DNDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEE
          DDSDD DFEIKEIAPPAAKKGGG + AA AKTTK     KK+EP A+LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR  I E EEE
Subjt:  DNDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEE

Query:  EEEGGNEDKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED
         EE GNE K+MGSASSETT EE A V  ARGRSQR  RTQVRYVVSDS+SEP  EDSDFDE +A+ DED
Subjt:  EEEGGNEDKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED

XP_022152631.1 DNA topoisomerase 2 isoform X1 [Momordica charantia]

0.0e+00

88.51

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNS  ANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL
        SVKVVIDVEQNCISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKR KKYKQ           
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL

Query:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
                                               VF DNMGKKSEP+ITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGK
Subjt:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK

Query:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK
        TVKVELNGQRVPVKSFQDYVDLYLKSAS F TEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVM VVNKKNKNANVK
Subjt:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK

Query:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS
        AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFG  CEL+PEFLKNVA+KSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG+NS
Subjt:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS

Query:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN
        EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI ENKEIQYIKQILGLQQGKEY+N K LRYGHLMIMTDQDHDGSHIKGLLIN
Subjt:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN

Query:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA
        FIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQDDHDGEAIELA
Subjt:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA

Query:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
        FSKKKIEERKNWLR FEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPS+VDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
Subjt:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL

Query:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI
        ASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFP+DDD+LLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+
Subjt:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI

Query:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP
        PNYNPRDII NV+RLLDGETM+PMDPWY+GFSG IEKTATKEGG SYTVSGIIEEVSDTTLRI ELPVR+WTNDYKEFLDSVTRVA +N  DKEKAAKDP
Subjt:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP

Query:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV
        FIEQADHHSDDK VSIDVHLTEENMILA+QEGLKKKFKLT T+STSNMHLFD+NGVIKKYDTPEQILEEFFPLRLE+YEKRK NLLENLE ELL+LENKV
Subjt:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV

Query:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVED
        RFILAVVNGEI+VSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNET+E EESPE KGERVSDY YLLALAIGTLTIEKVQELCNDRD+LKGEVED
Subjt:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVED

Query:  LRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRN-APKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASNAVVKPKGKAAA
        LRKATPKSLWLKDLD+LEKELDEMDRNDAQAEEVRKQQRIKANNDVKP+ISRN APKAPRNSKKT NSE + ESMDTTSSSTT EVASNAVVKPKGK AA
Subjt:  LRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRN-APKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASNAVVKPKGKAAA

Query:  PRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQV-QPAKKKEPSKRAPAKKKTTAKSAQNSDN
        PRKAPAKKGK  VVN +D DDDDEVLELKDRLAAYKI+SSPDRSE               VSAMETEVPQV   AKKKEPSKRAPAKKKTTAKSAQ SDN
Subjt:  PRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQV-QPAKKKEPSKRAPAKKKTTAKSAQNSDN

Query:  DDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAA-KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEE
        DDSDD+DFEIKE+APPAAKK GGGRKAA AKTTKPPAAAKKRE AA KLGQKLITQML P +N+GISPEKKVRK+RASPFNKKSGSILGRVG EE EEE 
Subjt:  DDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAA-KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEE

Query:  EEGGNEDKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED
        EE GNE KIMGSASSET EE+AG  PARGRSQRA RTQV+YV+SDS+S+P  E    D+KD DFD++
Subjt:  EEGGNEDKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED

XP_022152632.1 DNA topoisomerase 2 isoform X2 [Momordica charantia]

0.0e+00

88.39

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNS  ANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL
        SVKVVIDVEQNCISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKR KKYKQ           
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL

Query:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
                                               VF DNMGKKSEP+ITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGK
Subjt:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK

Query:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK
        TVKVELNGQRVPVKSFQDYVDLYLKSAS F TEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVM VVNKKNKNANVK
Subjt:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK

Query:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS
        AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFG  CEL+PEFLKNVA+KSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG+NS
Subjt:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS

Query:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN
        EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI ENKEIQYIKQILGLQQGKEY+N K LRYGHLMIMTDQDHDGSHIKGLLIN
Subjt:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN

Query:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA
        FIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQDDHDGEAIELA
Subjt:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA

Query:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
        FSKKKIEERKNWLR FEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPS+VDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
Subjt:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL

Query:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI
        ASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFP+DDD+LLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+
Subjt:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI

Query:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP
        PNYNPRDII NV+RLLDGETM+PMDPWY+GFSG IEKTATKEGG SYTVSGIIEEVSDTTLRI ELPVR+WTNDYKEFLDSVTRVA +N  DKEKAAKDP
Subjt:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP

Query:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV
        FIEQADHHSDDK VSIDVHLTEENMILA+QEGLKKKFKLT T+STSNMHLFD+NGVIKKYDTPEQILEEFFPLRLE+YEKRK NLLENLE ELL+LENKV
Subjt:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV

Query:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVED
        RFILAVVNGEI+VSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNET+E EESPE KGERVSDY YLLALAIGTLTIEKVQELCNDRD+LKGEVED
Subjt:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVED

Query:  LRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRN-APKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASNAVVKPKGKAAA
        LRKATPKSLWLKDLD+LEKELDEMDRNDAQAEEVRKQQRIKANNDVKP+ISRN APKAPRNSKKT NSE + ESMDTTSSSTT EVASNAVVKPKGK AA
Subjt:  LRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRN-APKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASNAVVKPKGKAAA

Query:  PRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQV-QPAKKKEPSKRAPAKKKTTAKSAQNSDN
        PRKAPAKKGK  VVN +D DDDDEVLELKDRLAAYKI+SSPDRSE                 AMETEVPQV   AKKKEPSKRAPAKKKTTAKSAQ SDN
Subjt:  PRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQV-QPAKKKEPSKRAPAKKKTTAKSAQNSDN

Query:  DDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAA-KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEE
        DDSDD+DFEIKE+APPAAKK GGGRKAA AKTTKPPAAAKKRE AA KLGQKLITQML P +N+GISPEKKVRK+RASPFNKKSGSILGRVG EE EEE 
Subjt:  DDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAA-KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEE

Query:  EEGGNEDKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED
        EE GNE KIMGSASSET EE+AG  PARGRSQRA RTQV+YV+SDS+S+P  E    D+KD DFD++
Subjt:  EEGGNEDKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED

XP_022935016.1 DNA topoisomerase 2 isoform X2 [Cucurbita moschata]

0.0e+00

88.39

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNAANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL
        S+KVVID EQN ISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQ           
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL

Query:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
                                               VFSDNMGKKSEPIITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
Subjt:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK

Query:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK
        TVKVELNGQRVPVKSFQDYVD YLKSA+AF TEPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK
Subjt:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK

Query:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS
        AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFG ACEL+P+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS
Subjt:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS

Query:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN
        EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI ENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLIN
Subjt:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN

Query:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA
        FIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELA
Subjt:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA

Query:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
        FSKKKIEERKNWLRQFE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
Subjt:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL

Query:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI
        ASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI
Subjt:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI

Query:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP
        PNYNPRDIIRNVRR+L+GE M+PMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRI ELPVR+WTNDYK+FLDSVTRV+ +NDKDKEKAAKDP
Subjt:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP

Query:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV
        FIEQADHHSDDK VSIDVHLTEENMILAMQEGLKKKFKLT T+STSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKV
Subjt:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV

Query:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVE
        RFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNET+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE
Subjt:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVE

Query:  DLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTAEVASNAVVKPKGKAA
        +LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQRIK NND+KP+ISRNAPKAPRNSKKTSNSE +TESMD TTSSSTT EVA+N VVKPKGK A
Subjt:  DLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTAEVASNAVVKPKGKAA

Query:  APRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSD
        APRKAPAKKGK AV+   D+DDDDEVLELKDRLAAYK+ESSP+ SE               VSAMETEVP+VQ  AKKKEPSKRA AKKKTTAKSAQ S 
Subjt:  APRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSD

Query:  NDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEE
         DDSDD DFEIKEIAPPAAKKGGG + AA AKTTK     KK+EP A+LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR  I E EEE 
Subjt:  NDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEE

Query:  EEGGNEDKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED
        EE GNE K+MGSASSETT EE A V  ARGRSQR  RTQVRYVVSDS+SEP  EDSDFDE +A+ DED
Subjt:  EEGGNEDKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED

XP_023527823.1 DNA topoisomerase 2 isoform X3 [Cucurbita pepo subsp. pepo]

0.0e+00

88.33

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNAANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLW+YENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL
        S+KVVID EQN ISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQ           
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL

Query:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
                                               VFSDNMGKKSEPIITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
Subjt:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK

Query:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK
        TVKVELNGQRVPVKSFQDYVD YLKSA+AF TEPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK
Subjt:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK

Query:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS
        AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFG ACEL+P+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS
Subjt:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS

Query:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN
        EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI ENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLIN
Subjt:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN

Query:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA
        FIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELA
Subjt:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA

Query:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
        FSKKKIEERKNWLRQFE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
Subjt:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL

Query:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI
        ASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI
Subjt:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI

Query:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP
        PNYNPRDIIRNVRR+L+GE M+PMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRI ELPVR+WTNDYK+FLDSVTRV+ +NDKDKEKAAKDP
Subjt:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP

Query:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV
        FIEQADHHSDDK VSIDVHLTEENMILAMQEGLKKKFKLT T+STSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKV
Subjt:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV

Query:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVE
        RFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNET+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE
Subjt:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVE

Query:  DLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTAEVASNAVVKPKGKAA
        +LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQRIK NNDVKP+ISRNAPKAPRNSKKTSNSE +TESMD TTSSSTT EVA+N VVKPKGK A
Subjt:  DLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTAEVASNAVVKPKGKAA

Query:  APRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSD
        APRKAPAKKGKAAV+   D+DDDDEVLELKDRLAAYK+ESSP+ SE               VSAMETEVP+VQ  AKKKEPSKRA AKKKTTAKSAQ S 
Subjt:  APRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSD

Query:  NDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEE
         DDSD+ DFEIKEIAPPAAKKGGG + AA AKTTK     KK+EP A+LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR   E  EEEE
Subjt:  NDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEE

Query:  EEGGNEDKIMGSASSETTEETAGVAP-ARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED
         E GNE K+MGSASSETT+E  G  P ARGRSQR  RTQVRYVVSDS+SEP  EDSDFDE +AD DED
Subjt:  EEGGNEDKIMGSASSETTEETAGVAP-ARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED

TrEMBL top hits

e value

%identity

Alignment

A0A6J1DGT3 DNA topoisomerase 2

0.0e+00

88.39

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNS  ANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL
        SVKVVIDVEQNCISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKR KKYKQ           
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL

Query:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
                                               VF DNMGKKSEP+ITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGK
Subjt:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK

Query:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK
        TVKVELNGQRVPVKSFQDYVDLYLKSAS F TEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVM VVNKKNKNANVK
Subjt:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK

Query:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS
        AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFG  CEL+PEFLKNVA+KSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG+NS
Subjt:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS

Query:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN
        EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI ENKEIQYIKQILGLQQGKEY+N K LRYGHLMIMTDQDHDGSHIKGLLIN
Subjt:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN

Query:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA
        FIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQDDHDGEAIELA
Subjt:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA

Query:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
        FSKKKIEERKNWLR FEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPS+VDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
Subjt:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL

Query:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI
        ASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFP+DDD+LLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+
Subjt:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI

Query:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP
        PNYNPRDII NV+RLLDGETM+PMDPWY+GFSG IEKTATKEGG SYTVSGIIEEVSDTTLRI ELPVR+WTNDYKEFLDSVTRVA +N  DKEKAAKDP
Subjt:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP

Query:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV
        FIEQADHHSDDK VSIDVHLTEENMILA+QEGLKKKFKLT T+STSNMHLFD+NGVIKKYDTPEQILEEFFPLRLE+YEKRK NLLENLE ELL+LENKV
Subjt:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV

Query:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVED
        RFILAVVNGEI+VSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNET+E EESPE KGERVSDY YLLALAIGTLTIEKVQELCNDRD+LKGEVED
Subjt:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVED

Query:  LRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRN-APKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASNAVVKPKGKAAA
        LRKATPKSLWLKDLD+LEKELDEMDRNDAQAEEVRKQQRIKANNDVKP+ISRN APKAPRNSKKT NSE + ESMDTTSSSTT EVASNAVVKPKGK AA
Subjt:  LRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRN-APKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASNAVVKPKGKAAA

Query:  PRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQV-QPAKKKEPSKRAPAKKKTTAKSAQNSDN
        PRKAPAKKGK  VVN +D DDDDEVLELKDRLAAYKI+SSPDRSE                 AMETEVPQV   AKKKEPSKRAPAKKKTTAKSAQ SDN
Subjt:  PRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQV-QPAKKKEPSKRAPAKKKTTAKSAQNSDN

Query:  DDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAA-KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEE
        DDSDD+DFEIKE+APPAAKK GGGRKAA AKTTKPPAAAKKRE AA KLGQKLITQML P +N+GISPEKKVRK+RASPFNKKSGSILGRVG EE EEE 
Subjt:  DDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAA-KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEE

Query:  EEGGNEDKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED
        EE GNE KIMGSASSET EE+AG  PARGRSQRA RTQV+YV+SDS+S+P  E    D+KD DFD++
Subjt:  EEGGNEDKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED

A0A6J1DIB5 DNA topoisomerase 2

0.0e+00

88.51

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNS  ANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL
        SVKVVIDVEQNCISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKR KKYKQ           
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL

Query:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
                                               VF DNMGKKSEP+ITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGK
Subjt:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK

Query:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK
        TVKVELNGQRVPVKSFQDYVDLYLKSAS F TEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVM VVNKKNKNANVK
Subjt:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK

Query:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS
        AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFG  CEL+PEFLKNVA+KSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGG+NS
Subjt:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS

Query:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN
        EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI ENKEIQYIKQILGLQQGKEY+N K LRYGHLMIMTDQDHDGSHIKGLLIN
Subjt:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN

Query:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA
        FIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQDDHDGEAIELA
Subjt:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA

Query:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
        FSKKKIEERKNWLR FEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPS+VDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
Subjt:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL

Query:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI
        ASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFP+DDD+LLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+
Subjt:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI

Query:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP
        PNYNPRDII NV+RLLDGETM+PMDPWY+GFSG IEKTATKEGG SYTVSGIIEEVSDTTLRI ELPVR+WTNDYKEFLDSVTRVA +N  DKEKAAKDP
Subjt:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP

Query:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV
        FIEQADHHSDDK VSIDVHLTEENMILA+QEGLKKKFKLT T+STSNMHLFD+NGVIKKYDTPEQILEEFFPLRLE+YEKRK NLLENLE ELL+LENKV
Subjt:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV

Query:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVED
        RFILAVVNGEI+VSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNET+E EESPE KGERVSDY YLLALAIGTLTIEKVQELCNDRD+LKGEVED
Subjt:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVED

Query:  LRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRN-APKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASNAVVKPKGKAAA
        LRKATPKSLWLKDLD+LEKELDEMDRNDAQAEEVRKQQRIKANNDVKP+ISRN APKAPRNSKKT NSE + ESMDTTSSSTT EVASNAVVKPKGK AA
Subjt:  LRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRN-APKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASNAVVKPKGKAAA

Query:  PRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQV-QPAKKKEPSKRAPAKKKTTAKSAQNSDN
        PRKAPAKKGK  VVN +D DDDDEVLELKDRLAAYKI+SSPDRSE               VSAMETEVPQV   AKKKEPSKRAPAKKKTTAKSAQ SDN
Subjt:  PRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQV-QPAKKKEPSKRAPAKKKTTAKSAQNSDN

Query:  DDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAA-KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEE
        DDSDD+DFEIKE+APPAAKK GGGRKAA AKTTKPPAAAKKRE AA KLGQKLITQML P +N+GISPEKKVRK+RASPFNKKSGSILGRVG EE EEE 
Subjt:  DDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAA-KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEE

Query:  EEGGNEDKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED
        EE GNE KIMGSASSET EE+AG  PARGRSQRA RTQV+YV+SDS+S+P  E    D+KD DFD++
Subjt:  EEGGNEDKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED

A0A6J1F3D6 DNA topoisomerase 2

0.0e+00

88.39

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNAANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL
        S+KVVID EQN ISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQ           
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL

Query:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
                                               VFSDNMGKKSEPIITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
Subjt:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK

Query:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK
        TVKVELNGQRVPVKSFQDYVD YLKSA+AF TEPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK
Subjt:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK

Query:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS
        AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFG ACEL+P+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS
Subjt:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS

Query:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN
        EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI ENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLIN
Subjt:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN

Query:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA
        FIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELA
Subjt:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA

Query:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
        FSKKKIEERKNWLRQFE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
Subjt:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL

Query:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI
        ASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI
Subjt:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI

Query:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP
        PNYNPRDIIRNVRR+L+GE M+PMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRI ELPVR+WTNDYK+FLDSVTRV+ +NDKDKEKAAKDP
Subjt:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP

Query:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV
        FIEQADHHSDDK VSIDVHLTEENMILAMQEGLKKKFKLT T+STSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKV
Subjt:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV

Query:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVE
        RFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNET+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE
Subjt:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVE

Query:  DLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTAEVASNAVVKPKGKAA
        +LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQRIK NND+KP+ISRNAPKAPRNSKKTSNSE +TESMD TTSSSTT EVA+N VVKPKGK A
Subjt:  DLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTAEVASNAVVKPKGKAA

Query:  APRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSD
        APRKAPAKKGK AV+   D+DDDDEVLELKDRLAAYK+ESSP+ SE               VSAMETEVP+VQ  AKKKEPSKRA AKKKTTAKSAQ S 
Subjt:  APRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSD

Query:  NDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEE
         DDSDD DFEIKEIAPPAAKKGGG + AA AKTTK     KK+EP A+LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR  I E EEE 
Subjt:  NDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEE

Query:  EEGGNEDKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED
        EE GNE K+MGSASSETT EE A V  ARGRSQR  RTQVRYVVSDS+SEP  EDSDFDE +A+ DED
Subjt:  EEGGNEDKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED

A0A6J1F9E0 DNA topoisomerase 2

0.0e+00

88.34

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNAANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL
        S+KVVID EQN ISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQ           
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL

Query:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
                                               VFSDNMGKKSEPIITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
Subjt:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK

Query:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK
        TVKVELNGQRVPVKSFQDYVD YLKSA+AF TEPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK
Subjt:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK

Query:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS
        AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFG ACEL+P+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS
Subjt:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS

Query:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN
        EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI ENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLIN
Subjt:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN

Query:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA
        FIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELA
Subjt:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA

Query:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
        FSKKKIEERKNWLRQFE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
Subjt:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL

Query:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI
        ASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI
Subjt:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI

Query:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP
        PNYNPRDIIRNVRR+L+GE M+PMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRI ELPVR+WTNDYK+FLDSVTRV+ +NDKDKEKAAKDP
Subjt:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP

Query:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV
        FIEQADHHSDDK VSIDVHLTEENMILAMQEGLKKKFKLT T+STSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKV
Subjt:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV

Query:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVE
        RFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNET+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE
Subjt:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVE

Query:  DLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTAEVASNAVVKPKGKAA
        +LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQRIK NND+KP+ISRNAPKAPRNSKKTSNSE +TESMD TTSSSTT EVA+N VVKPKGK A
Subjt:  DLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTAEVASNAVVKPKGKAA

Query:  APRKAPAKK-GKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNS
        APRKAPAKK GK AV+   D+DDDDEVLELKDRLAAYK+ESSP+ SE               VSAMETEVP+VQ  AKKKEPSKRA AKKKTTAKSAQ S
Subjt:  APRKAPAKK-GKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNS

Query:  DNDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEE
          DDSDD DFEIKEIAPPAAKKGGG + AA AKTTK     KK+EP A+LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR  I E EEE
Subjt:  DNDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEE

Query:  EEEGGNEDKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED
         EE GNE K+MGSASSETT EE A V  ARGRSQR  RTQVRYVVSDS+SEP  EDSDFDE +A+ DED
Subjt:  EEEGGNEDKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED

A0A6J1J555 DNA topoisomerase 2

0.0e+00

88.33

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVE KRPLQNSNAANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLW+YENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL
        S+KVVID EQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDT KKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQ           
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL

Query:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
                                               VFSDNMGKKSEPIITKCKE DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
Subjt:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK

Query:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK
        TVKVELNGQRVPVKSFQDYVD YLKSA+AF TEPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK
Subjt:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVK

Query:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS
        AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFG ACEL+P+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS
Subjt:  AHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNS

Query:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN
        EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI ENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLIN
Subjt:  EKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLIN

Query:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA
        FIHSFWP+LLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELA
Subjt:  FIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELA

Query:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
        FSKKKIEERKNWLRQFE GTHLDQ+EKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKIL+CSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL
Subjt:  FSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSL

Query:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI
        ASTIIGMAQDFVGSNNINLL+PNGQFGTRNHGGKDHASSRYIYTKLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI
Subjt:  ASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYI

Query:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP
        PNYNPRDIIRNVRR+LDGE M+PMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRI ELPVR+WTNDYK+FLDSVTRV+ +NDKDKEKAAKDP
Subjt:  PNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDP

Query:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV
        FIEQADHHSDDK VSI+VHLTEENMILAMQEGLKKKFKLT T+STSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKV
Subjt:  FIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV

Query:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVE
        RFILAVVNGEIIVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNET+E EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE
Subjt:  RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVE

Query:  DLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTAEVASNAVVKPKGKAA
        +LRKATPKSLWLKDLD LEKELDEMDRNDAQA+EVRKQQRIK NND+KP+ISRNAPKAPRNSKKTSNSE +TESMD  TSSSTT EVA+N VVKPKGK A
Subjt:  DLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMD-TTSSSTTAEVASNAVVKPKGKAA

Query:  APRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSD
        APRKAPAKKGKAAV+   D+D DDEVLELKDRLAAYK+ESSP+ SE               VSAMETEVP+VQ  AKKKEPSKRA AKKKTTAKSAQ S 
Subjt:  APRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQ-PAKKKEPSKRAPAKKKTTAKSAQNSD

Query:  NDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEE
         DDSDD DFEIKEIAPPAAKKGGG + AA AKTTK     KK+EP A+LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR  I E EEE 
Subjt:  NDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEE

Query:  EEGGNEDKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED
        EE GNE K+MGSASSETT EE A V  ARGRSQR  RTQVRYVVSDS+SEP  EDSDFDE +AD DED
Subjt:  EEGGNEDKIMGSASSETT-EETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED

SwissProt top hits

e value

%identity

Alignment

O24308 DNA topoisomerase 2

0.0e+00

61.16

Show/hide

Query:  KKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKV
        +KRPLQ SNAAN+      P KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHR+V+YVPGLYKIFDEILVNAADNKQRDPSMDS+KV
Subjt:  KKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKV

Query:  VIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCLNPFS
         ID E N +SV+NNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDD VKKTTGGRNGYGAKLTNIFSTEF+IETADG+RLKKYKQ               
Subjt:  VIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCLNPFS

Query:  PLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKV
                                           VFS+NMG K EP+ITKCK S+NWTKVTFKPDL KF M +LE+DVVALMKKRVLD+AGC GKTVKV
Subjt:  PLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKV

Query:  ELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNV
        ELNG  +  KSF+DY DL+LK A      P  R H K  +RWEI ++LS+GQFQQVSFVN IATIKGGTHVDYITNQI  Y+M  VNKK K+ANVKAH V
Subjt:  ELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNV

Query:  KSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCT
        K++LWVF+N+LIDNPAFDSQTKETLT RQ+SFG  C++    LK+V  KSGI+D++LSW +FKQSKDLKKTDG KT+++ G  K EDAN AGG+NSEKCT
Subjt:  KSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCT

Query:  LILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHS
        LILTEGDSAKALAMAGL VVGRD YGVFPLRGKLLNVREASSKQIM+N+EIQ IK+ILGLQQ KEY+N K+LRYGHLMIM DQDHDGSHIKGLLINFIHS
Subjt:  LILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHS

Query:  FWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKK
        FWP+LL+VPSFLVEF TP+++A+H N T+ SFY+MPEYE+WKE L  +A+ W IKYYKGLGTST +EGREYF  L +H+KDFIW D+ DG AIELAFSKK
Subjt:  FWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKK

Query:  KIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTI
        K E RK W+R FEPGT  D   KLI Y DFVNKELILFS AD                   L+ SFK+   KE KV+QF GYVSEHSAYHHGEQSLASTI
Subjt:  KIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTI

Query:  IGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYN
        IGMAQDFVGSNNINLL PNGQFGT N GGKDHAS+RYIYT+LS VTR LF + DDKLL YLNEDG+SIEP WYMPIIP VLVNGSEGIGTGWSSYIPNYN
Subjt:  IGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYN

Query:  PRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDPFIEQ
        PR+II NVRRLL+GE +VPMDPWY+GF GTIEK+A KEGG  Y V+G + E+ + T RI ELP+RKWT DYK+FL+S+T        D     KDP IE 
Subjt:  PRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAKDPFIEQ

Query:  ADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFIL
           + DD IV I++ +  E +   +QEGL KKFKLT+TISTSNMHLFDA G  KK+DTPEQILEEFFPLRL++YEK K  +L NL   LL L+NKVRFIL
Subjt:  ADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFIL

Query:  AVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPE---------VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLK
         VVNGEIIVSNR++ +L  EL+ KGFTP P+K KS +P+VAGA+++  E +E  E         V+G    DY+ LL+L IGTLT+E VQ+L +++ + +
Subjt:  AVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPE---------VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLK

Query:  GEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASNAVVKPKG
         E E L      SLWLKDLD  EK+LDE+D   A+ +  R  Q  K  N    + ++  P+  +N+KK        +S++  + +++ E+  NAV     
Subjt:  GEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASNAVVKPKG

Query:  KAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQPAKKKEPSKRAPAKKK-TTAKSAQ
        +AA P +    KG+AA   +  ++ +D++  L++RLAAY IESS ++S+                 AME+E  Q + A KK+ +KR  AKKK +T     
Subjt:  KAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQPAKKKEPSKRAPAKKK-TTAKSAQ

Query:  NSDND--DSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAA----------KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSG
        +SDN+  D DD+D + +E+   AA    GGRK AA    K PA A  + PAA            GQKL+T ML+PAE +G SPEKKVRK+R SPFNKKSG
Subjt:  NSDND--DSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAA----------KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSG

Query:  SILGRVGIEEVEEEEEEGGNEDKIMGSASSETTEETAGV----APARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED
        SILGR         ++     D   GSAS+    E   V     PAR R QRA RTQ++Y +S+SESE   EDSD D + +DF+ED
Subjt:  SILGRVGIEEVEEEEEEGGNEDKIMGSASSETTEETAGV----APARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED

O46374 DNA topoisomerase 2-alpha

0.0e+00

44.49

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPTGPKK--TIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMV-HRSVTYVPGLYKIFDEILVNAADNKQRDP
        M V   +P+  +   N  +     KK  +IE +YQKKTQLEHILLRPDTY+GS+E  TQ +WVY+ D  + +R VT+VPGLYKIFDEILVNAADNKQRDP
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKK--TIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMV-HRSVTYVPGLYKIFDEILVNAADNKQRDP

Query:  SMDSVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDL
         M  ++V ID E N IS++NNG G+PV  H+ EK+YVP LIFG LLTSSNYDD  KK TGGRNGYGAKL NIFST+F +ETA     ++YK++       
Subjt:  SMDSVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDL

Query:  LCLNPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGC
                                               F + + DNMG+  E +  K    +++T +TF PDL+KF M  L+ D+VALM +R  D+AG 
Subjt:  LCLNPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGC

Query:  LGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNK-N
          K VKV LNG ++PVK F+ YVDLYLK     +  P K  H + N RWE+ +T+SE  FQQ+SFVN IAT KGG HVDY+ +QI   ++ VV KKNK  
Subjt:  LGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNK-N

Query:  ANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCA
          VKAH VK+++W+F+NALI+NP FDSQTKE +T++  SFG  C+LS +F+K  A   GI++S+L+WV FK    L KK    K  +I GI KL+DAN A
Subjt:  ANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCA

Query:  GGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEY---SNAKALRYGHLMIMTDQDHDGS
        GG+NS +CTLILTEGDSAK LA++GLGVVGRD YGVFPLRGK+LNVREAS KQIMEN EI  I +I+GLQ  K Y    + K LRYG +MIMTDQD DGS
Subjt:  GGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEY---SNAKALRYGHLMIMTDQDHDGS

Query:  HIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDH
        HIKGLLINFIH  WP+LLR   FL EFITPIVK + +N   ++FY++PE+E WK S   N   W +KYYKGLGTSTSKE +EYF  + +H+  F +    
Subjt:  HIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDH

Query:  DGEAIELAFSKKKIEERKNWLRQFE-----------PGTHL-DQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKV
        D  AI LAFSKK+I++RK WL  F            P  +L  QT   + Y+DF+NKELILFS +D +RSIPSMVDGLKPGQRK+L+  FKRN  +E KV
Subjt:  DGEAIELAFSKKKIEERKNWLRQFE-----------PGTHL-DQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKV

Query:  SQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPI
        +Q +G V+E S+YHHGE SL  TII +AQ+FVGSNN+NLL P GQFGTR HGGKD AS RYI+T LS + R LFP  DD  L +L +D Q +EP WY+PI
Subjt:  SQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPI

Query:  IPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLD
        IP VL+NG+EGIGTGWS  IPN++ R+++ N+R L+DGE  +PM P Y+ F GTIE+ A  +    Y +SG +  ++ TT+ I ELP+R WT  YKE   
Subjt:  IPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLD

Query:  SVTRVAARNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEK
           +V        EK    P I     +  D  V   V +TEE +  A + GL K FKL  +++ ++M LFD  G +KKYDT   IL +FF LRL++Y  
Subjt:  SVTRVAARNDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEK

Query:  RKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKT-KSVEPEVAGASNETEETEESPEVKGERVSD----YEYLLALA
        RK  LL  L  E  KL N+ RFIL  ++G+II+ N+ + +L   L  +G+   P K  K  + +V       E   E    K + V+D    + YLL + 
Subjt:  RKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKT-KSVEPEVAGASNETEETEESPEVKGERVSD----YEYLLALA

Query:  IGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEV-----------RKQQRIK-----ANNDVKPRIS----RNAP
        +  LT EK  ELC  R++ + E+E L++ +P  LW +DL +  +EL+ ++  + Q E++           +K Q  +         V PR++      A 
Subjt:  IGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEV-----------RKQQRIK-----ANNDVKPRIS----RNAP

Query:  KAPRNSKKTSNSEAVTE----SMDTTSSSTTAEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDD--DDE------VLELKDRLAAYK------IE
        K  +   K+ N+E   +     ++        +       K K +   P K P KK K      D E D   DE        E + R AA K      ++
Subjt:  KAPRNSKKTSNSEAVTE----SMDTTSSSTTAEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDD--DDE------VLELKDRLAAYK------IE

Query:  SSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQPAKKKEPSKRAPAKKKTTAKSAQNS--DNDDSDDEDF-EIKEIAPPAAKKGGGGRKAAA-AKTTKP
        S  D S+ D++ TR    V    S  + E       K+ +P K  P+     A  A+++   +  S   DF  + E   P +KK    +K AA ++++  
Subjt:  SSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQPAKKKEPSKRAPAKKKTTAKSAQNS--DNDDSDDEDF-EIKEIAPPAAKKGGGGRKAAA-AKTTKP

Query:  PAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEGGNED
           AKKR  AA  G K    +          P+ K R+ R    +  S S   ++  + V  ++ +G ++D
Subjt:  PAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEGGNED

P08096 DNA topoisomerase 2

0.0e+00

46.44

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVY--ENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPS
        M   ++ PL  +N      + T         YQ+ T  EH+L RPDTY+GSIE  T  +WV+  E +K+ +++VTYVPGLYKIFDEI+VNAADNK RDP+
Subjt:  MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVY--ENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPS

Query:  MDSVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLL
        M+++KV +D E N IS++NNG G+P+E+H +EK+Y+PELIFG+LLTSSNYDD  KK TGGRNGYGAKL NIFSTEFV+ETAD +R+KKYKQ         
Subjt:  MDSVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLL

Query:  CLNPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCL
                                                  + DNM +KSEP+IT  K+ D +TK+TFKPDLAKF M  ++DD+V+++K+R+ D+AG +
Subjt:  CLNPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCL

Query:  GKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNAN
         +T KV LN +R+ +  F+ YV++YL S +    EPP+  +   N+RW++   +S+GQF+QVSFVN I+TI+GGTHV+Y+ N+I + +  VV K+NK A 
Subjt:  GKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNAN

Query:  VKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGK
        VKA  +K+Y+ VF+N  I+NP+FDSQTKETLT + S+FG  C LS +FLK +  KS +++ VL +   K  + L K DG    +I+G+ KLEDAN AG K
Subjt:  VKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGK

Query:  NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLL
         S KC LILTEGDSAK+LA++GL VVGRD+YGVFPLRGKLLNVREAS  QI+ NKEIQ IK+I+G    K Y++ K LRYGHLMIMTDQDHDGSHIKGL+
Subjt:  NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLL

Query:  INFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIE
        IN++ S +P+LL++P FL++FITPI+K T R   V +FYT+PEYE WKE+   N  GW IKYYKGLGTS   + + YF  L +H K F    + D E IE
Subjt:  INFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIE

Query:  LAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQ
        +AF+KKK + RK WLR + PG ++D T+  I   DF+N+ELI FSMAD  RSIPS+VDGLKPGQRK++Y  FKRN + E KVS+ +GYV+  +AYHHGE 
Subjt:  LAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQ

Query:  SLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSS
        S+  TI+ +AQ+FVGSNNINLLMPNGQFGTR+ GGK+ ++SRY+ T LS + R LF  +DD+LLNY N++GQ IEP +Y+PI+P VLVNG+EGIGTGWS+
Subjt:  SLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSS

Query:  YIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAK
        +IPNYNP+DI  N+R +L+GE +  M PWYRGF G+I K A       Y +SGII ++ +  + I ELP+R WT D KE+L++            EK  K
Subjt:  YIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAAK

Query:  DPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLEN
          FI   + H  +  V  +V LTE  M  A+ E L+ KFKL+ T +TSNM  FDA+G IKKYD+ E IL EF+ +RL  Y++RK +++  LE    +  N
Subjt:  DPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLEN

Query:  KVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPF--PKKTKSVEPEVAGASNETEETEESPEVKGERVSD-YEYLLALAIGTLTIEKVQELCNDRDKLK
        + RFI  ++ GE++VS +++ DL  EL+ K F P   PKK   V+ EV    N   E E+S +V  +  SD Y YLL++ + +LT E+  EL   +D++ 
Subjt:  KVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPF--PKKTKSVEPEVAGASNETEETEESPEVKGERVSD-YEYLLALAIGTLTIEKVQELCNDRDKLK

Query:  GEVEDLRKATPKSLWLKDLDSLE----KELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASNAVV
         E++ L K TPK LWL DLD+ E    K +D++ R     EE +  +        KPR      + PR    +S+S AV +   + S  +T       ++
Subjt:  GEVEDLRKATPKSLWLKDLDSLE----KELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASNAVV

Query:  KPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQPAKKKEPSKRAPAKKKTTAK
        +      A  K P K     +V  +D      V E        +I  SP     D   +R         S    +    +P KK   S     +K     
Subjt:  KPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQPAKKKEPSKRAPAKKKTTAK

Query:  SAQNSDNDDSDD---EDFEIKEIAPPAAKKGGGGRKAAAAKTTKP
        +     +DD DD      +   I    A     G+KA++ K   P
Subjt:  SAQNSDNDDSDD---EDFEIKEIAPPAAKKGGGGRKAAAAKTTKP

P30182 DNA topoisomerase 2

0.0e+00

61.08

Show/hide

Query:  KRPLQNSNAANVDQIPTGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNAANV + P   +     KTIEEMYQKK+QLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R VTYVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNAANVDQIPTGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL
        SV+VVIDVEQN ISV N+G GVPVE+HQEE +YVPE+IFGHLLTSSNYDD VKKTTGGRNGYGAKLTNIFSTEF+IETADGKRLKKYKQ           
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL

Query:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
                                               VF +NMGKKSEP+ITKC +S+NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK
Subjt:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK

Query:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANV
        +VKVELNG+++PVKSF DYVDLYL +A+   TE P  R   K N+RWE+ V+LSEGQFQQVSFVN IATIKGGTHVDY+T+QI N+++  VNKKNKNANV
Subjt:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANV

Query:  KAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKN
        KAHNVK++LWVF+NALIDNPAFDSQTKETLT+RQSSFG  CELS +FLK V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKN
Subjt:  KAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKN

Query:  SEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLI
        S  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI  NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLI
Subjt:  SEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLI

Query:  NFIHSFWPTLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAI
        NFIHSFWP+LL+VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WKESL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAI
Subjt:  NFIHSFWPTLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAI

Query:  ELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGE
        ELAFSKKKIE RKNWL  + PG HLDQ +  + YSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKIL+ +FK+   KE KV+Q  GYVS  SAYHHGE
Subjt:  ELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGE

Query:  QSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWS
        QSLAS IIGMAQD+VGSNNINLL+PNGQFGTR  GGKD AS+RYI+TKLS VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS
Subjt:  QSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWS

Query:  SYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAA
        ++IPNYNPR+I+ NVRRLL+GE+MVPMDPWYRGF GTIEKTA+KEGG +YT++G+ EEV +TT+RI ELP+R+W +DYK FL S+     + D       
Subjt:  SYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAA

Query:  KDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLE
          PF +    ++D+K V  D+ L+EENM+ A QEG  KKFKLT TI+TSNMHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  +++N+E+ELLKLE
Subjt:  KDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLE

Query:  NKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAG-----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCND
        NK RFILAV++GEIIV+ R++ D+  +L+ KGFTPFP+K +SVE  +AG     A+ E EE    PE     +  S+Y+YLLA+AI +LTIEKV+EL  D
Subjt:  NKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAG-----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCND

Query:  RDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEV--RKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASN
        RDK+   V D++K TPKSLWL DL+SL+KEL+++D  DAQ ++     Q++I+A +    ++ R APK P   KKT+   + +E+ + + S+   +    
Subjt:  RDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEV--RKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASN

Query:  AVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDD-DEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQPAKKKEPSKR---APA
         VVKPK +  A +KA   +   A  +  D D++  EV++ K R  A K                       P +A E E  ++    ++        APA
Subjt:  AVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDD-DEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQPAKKKEPSKR---APA

Query:  KKKTTAKSAQNSDNDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSI
            TA++++    DD DD+   + E+AP   KK  GGRK AA K  KPPAA +KR        +++          G+SPEKKVRK+R+SPFNKKS S+
Subjt:  KKKTTAKSAQNSDNDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSI

Query:  LGRVGIEEVEEEEEEGGNEDKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED
        + R+   + EE  E       + G++SS   E++ G   A  R QRA R ++ YV+SDSESE A+ DS+FD+ + D D++
Subjt:  LGRVGIEEVEEEEEEGGNEDKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED

Q55BP5 Probable DNA topoisomerase 2

0.0e+00

45.75

Show/hide

Query:  KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVE
        K+IEE+YQKK  L+ ILLRPDTY+GS E+  + LWV+E+ +MVHR V++VPG+YKIFDEILVNAADNKQR+ +M  +KVVID E+  ISV N+G G+P++
Subjt:  KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVE

Query:  VHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCLNPFSPLSLIKIVRLLHVIFPFLNVA
        VH E K+Y+PELIFG+LLTSS+YDD+ K+ TGGRNG+GAKL NIFST+F++E AD K  K YKQ                                    
Subjt:  VHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCLNPFSPLSLIKIVRLLHVIFPFLNVA

Query:  SRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLK
                       F++NM  K +P IT  +   ++TK+TF P+L +F M   +DD+VAL+ KRV D+AGC   T+KV LN + + ++SF+ Y++LY  
Subjt:  SRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLK

Query:  SASAFSTEPPKRYHIKPNERWEIVVTLS-EGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDS
                 PK Y+ K ++RWE+ VTLS E QF QVSFVN I T+KGGTHV +  + I   +   VNKKNK +A++K   +K++L VF+N LI+NP FDS
Subjt:  SASAFSTEPPKRYHIKPNERWEIVVTLS-EGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDS

Query:  QTKETLTIRQSSFGCACELSPEFLKNVA-TKSGIMDSVLSWVNFKQSKDLKK--TDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAG
        QTKETLT + SSFG  CE S +F+K V  +KSGI+ S+L +  FK    LK+  + G K  K+S I KL+DAN AGG  SE CTLILTEGDSAK+LA AG
Subjt:  QTKETLTIRQSSFGCACELSPEFLKNVA-TKSGIMDSVLSWVNFKQSKDLKK--TDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAG

Query:  LGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFI
        + VVG+D YG FPL+GKLLNVR+ S+K ++ N EI  I  ILGL+ GK Y     LRYGHLMIMTDQDHDGSHIKGL+IN +H FWPTLLR+P FLVEFI
Subjt:  LGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFI

Query:  TPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGT
        TPIVK    N   +SFYTMPE+  W+E+   N  GW +KYYKGLGTST  EG+EYF  L +HK DF W D+   + IELAFSK + ++RK W+ +   GT
Subjt:  TPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGT

Query:  HLDQ-TEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINL
         L+Q   K + YSDF+NKEL+LFS+AD +RSIP++VDGLK   RK LY  FKRN  KE KV+Q  GYVSEHSAYHHGE SL STI+GMAQ+FVGSNNINL
Subjt:  HLDQ-TEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINL

Query:  LMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGE
        L P G +GTR  GGKD +S+RYI+T+L+++ R ++  DDD +L+ + +DG+ ++P +Y+P+IP +LVNG  GIGTGWSS IPNYNPRD+I+N+R  +DG+
Subjt:  LMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGE

Query:  TMVPMDPWYRGFSGTIE-KTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSV----TRVAARNDKDKEKA------AKDPFIEQADHH
         + P+ PWYRGF G+IE    +K  G  Y   GI +++SD    I ELP+  WT DY+E LD +    TR   + +K+K+ A      AK    +++   
Subjt:  TMVPMDPWYRGFSGTIE-KTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSV----TRVAARNDKDKEKA------AKDPFIEQADHH

Query:  SDD----KIVSIDV------------HLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEME
         DD    K+    V            H   + +    +  ++K FKL +TI+ +NM +FD  G I+++ T   + E FFPLR++ Y+ RK  L E L  E
Subjt:  SDD----KIVSIDV------------HLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEME

Query:  LLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPF------------PKKTKSVEPEVAGASNETEETEESPEVKGERVSDYEYLLALAIGTLT
          +L NK RFILAVVN E+++SN ++VDL ++L+   F                KK K+   E   A +  EE + + E + +    Y+YLL+L + +LT
Subjt:  LLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPF------------PKKTKSVEPEVAGASNETEETEESPEVKGERVSDYEYLLALAIGTLT

Query:  IEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDA----QAEEVRKQQRIKANNDVKP------RISRNAP---------KAPRNS
        +E+V++L  +RD  K E + L     + ++ +DLD+LEK LD+ D  D     Q E ++K+ + KA    K       + ++ AP         K P  +
Subjt:  IEKVQELCNDRDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDA----QAEEVRKQQRIKANNDVKP------RISRNAP---------KAPRNS

Query:  KKTSNSEAVTESMDTTSSSTTAEVASNAVVKPKGKAAAPRK-APAKKGKAAVVNDDDED-DDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFP
            +     +S DTTS+ST+   +SN        A   +K  PA K    V  D D D DDD V+  K +    K     + S+  DQ +         
Subjt:  KKTSNSEAVTESMDTTSSSTTAEVASNAVVKPKGKAAAPRK-APAKKGKAAVVNDDDED-DDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFP

Query:  VSAMETEVPQVQPAKKKEPSKRAP--AKKKTTAKSAQNSDNDDSDDE
          + +   P+  P + K P K+    A KK T   ++  D+  SDDE
Subjt:  VSAMETEVPQVQPAKKKEPSKRAP--AKKKTTAKSAQNSDNDDSDDE

Arabidopsis top hits

e value

%identity

Alignment

AT3G10270.1 DNA GYRASE B1

3.1e-19

23.12

Show/hide

Query:  GLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNY--DDTVKKTTGGRNGYGAKLTNIFSTEF
        GL+ +  EIL NA D  Q       + VV+  + + +S+ +NG G+P ++H        E +   L     +    +    +GG +G G  + N  S   
Subjt:  GLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNY--DDTVKKTTGGRNGYGAKLTNIFSTEF

Query:  -VIETADG----KRLKKYKQLSCLSIDLL----------CLNPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKES
         VI   DG    ++  + K ++ L+  +L          C+  F P    K V    + F    +A R    ++L+      + ++ K+ +       E 
Subjt:  -VIETADG----KRLKKYKQLSCLSIDLL----------CLNPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKES

Query:  DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQ
        D +++  +   L ++ ++ L  D     KK + D+ G      + E+NG  V V S Q   D Y  +                                 
Subjt:  DNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQ

Query:  VSFVNGIATIKGGTHVDYITNQIANYVMTVVNK------------------------------------KNKNANVKAHNVKSYLWVFINALIDNPAFDS
        + + N I TI GGTH++ +   +   + ++  K                                      K+ ++   +V+  L   ++  + NP F+ 
Subjt:  VSFVNGIATIKGGTHVDYITNQIANYVMTVVNK------------------------------------KNKNANVKAHNVKSYLWVFINALIDNPAFDS

Query:  QTKETL---TIR-------QSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDS
        QTK  L    +R       Q       EL P+ L+++ +KS  +++  + +  K++++L ++    K+  + G  KL D +      SE   + + EGDS
Subjt:  QTKETL---TIR-------QSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDS

Query:  AKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRV
        A   A  G     R F  + PLRGK+LN+       + +N+EIQ +   LGL    E  N + LRY  ++I+TD D DG+HI+ LL+ F   +   L   
Subjt:  AKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRV

Query:  PSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLG
            V  + P+ K   R       Y     +    S  GNAS ++I+ +KGLG
Subjt:  PSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLG

AT3G23890.1 topoisomerase II

0.0e+00

61.08

Show/hide

Query:  KRPLQNSNAANVDQIPTGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNAANV + P   +     KTIEEMYQKK+QLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R VTYVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNAANVDQIPTGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL
        SV+VVIDVEQN ISV N+G GVPVE+HQEE +YVPE+IFGHLLTSSNYDD VKKTTGGRNGYGAKLTNIFSTEF+IETADGKRLKKYKQ           
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL

Query:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
                                               VF +NMGKKSEP+ITKC +S+NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK
Subjt:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK

Query:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANV
        +VKVELNG+++PVKSF DYVDLYL +A+   TE P  R   K N+RWE+ V+LSEGQFQQVSFVN IATIKGGTHVDY+T+QI N+++  VNKKNKNANV
Subjt:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANV

Query:  KAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKN
        KAHNVK++LWVF+NALIDNPAFDSQTKETLT+RQSSFG  CELS +FLK V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKN
Subjt:  KAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKN

Query:  SEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLI
        S  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI  NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLI
Subjt:  SEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLI

Query:  NFIHSFWPTLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAI
        NFIHSFWP+LL+VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WKESL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAI
Subjt:  NFIHSFWPTLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAI

Query:  ELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGE
        ELAFSKKKIE RKNWL  + PG HLDQ +  + YSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKIL+ +FK+   KE KV+Q  GYVS  SAYHHGE
Subjt:  ELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGE

Query:  QSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWS
        QSLAS IIGMAQD+VGSNNINLL+PNGQFGTR  GGKD AS+RYI+TKLS VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS
Subjt:  QSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWS

Query:  SYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAA
        ++IPNYNPR+I+ NVRRLL+GE+MVPMDPWYRGF GTIEKTA+KEGG +YT++G+ EEV +TT+RI ELP+R+W +DYK FL S+     + D       
Subjt:  SYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAA

Query:  KDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLE
          PF +    ++D+K V  D+ L+EENM+ A QEG  KKFKLT TI+TSNMHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  +++N+E+ELLKLE
Subjt:  KDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLE

Query:  NKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAG-----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCND
        NK RFILAV++GEIIV+ R++ D+  +L+ KGFTPFP+K +SVE  +AG     A+ E EE    PE     +  S+Y+YLLA+AI +LTIEKV+EL  D
Subjt:  NKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAG-----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCND

Query:  RDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEV--RKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASN
        RDK+   V D++K TPKSLWL DL+SL+KEL+++D  DAQ ++     Q++I+A +    ++ R APK P   KKT+   + +E+ + + S+   +    
Subjt:  RDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEV--RKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASN

Query:  AVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDD-DEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQPAKKKEPSKR---APA
         VVKPK +  A +KA   +   A  +  D D++  EV++ K R  A K                       P +A E E  ++    ++        APA
Subjt:  AVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDD-DEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQPAKKKEPSKR---APA

Query:  KKKTTAKSAQNSDNDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSI
            TA++++    DD DD+   + E+AP   KK  GGRK AA K  KPPAA +KR        +++          G+SPEKKVRK+R+SPFNKKS S+
Subjt:  KKKTTAKSAQNSDNDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSI

Query:  LGRVGIEEVEEEEEEGGNEDKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED
        + R+   + EE  E       + G++SS   E++ G   A  R QRA R ++ YV+SDSESE A+ DS+FD+ + D D++
Subjt:  LGRVGIEEVEEEEEEGGNEDKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED

AT3G23890.2 topoisomerase II

0.0e+00

61.23

Show/hide

Query:  KRPLQNSNAANVDQIPTGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNAANV + P   +     KTIEEMYQKK+QLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R VTYVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNAANVDQIPTGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL
        SV+VVIDVEQN ISV N+G GVPVE+HQEE +YVPE+IFGHLLTSSNYDD VKKTTGGRNGYGAKLTNIFSTEF+IETADGKRLKKYKQ           
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCL

Query:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
                                               VF +NMGKKSEP+ITKC +S+NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK
Subjt:  NPFSPLSLIKIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK

Query:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANV
        +VKVELNG+++PVKSF DYVDLYL +A+   TE P  R   K N+RWE+ V+LSEGQFQQVSFVN IATIKGGTHVDY+T+QI N+++  VNKKNKNANV
Subjt:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANV

Query:  KAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKN
        KAHNVK++LWVF+NALIDNPAFDSQTKETLT+RQSSFG  CELS +FLK V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKN
Subjt:  KAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKN

Query:  SEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLI
        S  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI  NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLI
Subjt:  SEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLI

Query:  NFIHSFWPTLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAI
        NFIHSFWP+LL+VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WKESL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAI
Subjt:  NFIHSFWPTLLRVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAI

Query:  ELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGE
        ELAFSKKKIE RKNWL  + PG HLDQ +  + YSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKIL+ +FK+   KE KV+Q  GYVS  SAYHHGE
Subjt:  ELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSFKRNFIKEAKVSQFSGYVSEHSAYHHGE

Query:  QSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWS
        QSLAS IIGMAQD+VGSNNINLL+PNGQFGTR  GGKD AS+RYI+TKLS VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS
Subjt:  QSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWS

Query:  SYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAA
        ++IPNYNPR+I+ NVRRLL+GE+MVPMDPWYRGF GTIEKTA+KEGG +YT++G+ EEV +TT+RI ELP+R+W +DYK FL S+     + D       
Subjt:  SYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARNDKDKEKAA

Query:  KDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLE
          PF +    ++D+K V  D+ L+EENM+ A QEG  KKFKLT TI+TSNMHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  +++N+E+ELLKLE
Subjt:  KDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLE

Query:  NKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAG-----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCND
        NK RFILAV++GEIIV+ R++ D+  +L+ KGFTPFP+K +SVE  +AG     A+ E EE    PE     +  S+Y+YLLA+AI +LTIEKV+EL  D
Subjt:  NKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAG-----ASNETEETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCND

Query:  RDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEV--RKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASN
        RDK+   V D++K TPKSLWL DL+SL+KEL+++D  DAQ ++     Q++I+A +    ++ R APK P   KKT+   + +E+ + + S+   +    
Subjt:  RDKLKGEVEDLRKATPKSLWLKDLDSLEKELDEMDRNDAQAEEV--RKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASN

Query:  AVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQPAKKKEPSKRAPAKKKT
         VVKPKG+  A +KAPA            E ++DE+L+L  RLA Y   S                                           APA    
Subjt:  AVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDDDDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQPAKKKEPSKRAPAKKKT

Query:  TAKSAQNSDNDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRV
        TA++++    DD DD+   + E+AP   KK  GGRK AA K  KPPAA +KR        +++          G+SPEKKVRK+R+SPFNKKS S++ R+
Subjt:  TAKSAQNSDNDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKTTKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRV

Query:  GIEEVEEEEEEGGNEDKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED
           + EE  E       + G++SS   E++ G   A  R QRA R ++ YV+SDSESE A+ DS+FD+ + D D++
Subjt:  GIEEVEEEEEEGGNEDKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVVSDSESEPASEDSDFDEKDADFDED

AT5G04130.1 DNA GYRASE B2

1.4e-24

23.68

Show/hide

Query:  AANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCI
        +    Q  T  K    E  Q    L+ +  RP  Y+GS                     T   GL+ +  EIL NA D  Q   +   V VV+  +   +
Subjt:  AANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCI

Query:  SVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVK--KTTGGRNGYGAKLTNIFSTEFVIET-ADGKRLK----KYKQLSCLSIDLLCLNPFSPL
        SV +NG G+P ++H   K    E +   L     +  T      +GG +G G  + N  S    +    DG   K    + K ++ L+  +L L      
Subjt:  SVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVK--KTTGGRNGYGAKLTNIFSTEFVIET-ADGKRLK----KYKQLSCLSIDLLCLNPFSPL

Query:  SLI------KIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK
                 K V    + F    +A R    ++L+      + ++ K+ +       E   +++ +F   L ++ ++ L  D     K  + D+ G    
Subjt:  SLI------KIVRLLHVIFPFLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGK

Query:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNK----KNKN
          + E+NG  V V + Q   D Y  +                                 + + N I TI GGTH++ +   +   + T+  K    K K+
Subjt:  TVKVELNGQRVPVKSFQDYVDLYLKSASAFSTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNK----KNKN

Query:  ANVKAHNVKSYLWVFINALIDNPAFDSQTKETL---TIR-------QSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISG
         ++   +V+  L   ++  + NP F+ QTK  L    +R       Q       EL P+ L+++ +KS  +++  + +  K++++L ++    K+  + G
Subjt:  ANVKAHNVKSYLWVFINALIDNPAFDSQTKETL---TIR-------QSSFGCACELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISG

Query:  IEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMT
          KL D +    + SE   + + EGDSA   A  G     R F  + PLRGK+LN+       + +N+EIQ +   LGL    E    + LRY  ++I+T
Subjt:  IEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIMENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMT

Query:  DQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLG
        D D DG+HI+ LL+ F   +   L       V  + P+ K   R       Y   + +    +   NAS ++I+ +KGLG
Subjt:  DQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLG

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGGCCGTGGAGAAGAAGCGCCCACTGCAGAACAGCAACGCCGCCAATGTCGACCAGATTCCGACCGGGCCGAAGAAAACGATCGAAGAAATGTACCAGAAGAAGACTCA
GCTCGAGCACATTCTCCTCAGGCCCGATACTTATGTTGGATCGATCGAAAAGCACACTCAAAATCTCTGGGTTTACGAGAACGACAAGATGGTGCACCGATCCGTTACCT
ACGTGCCGGGTCTCTACAAGATCTTTGATGAAATTTTGGTCAATGCTGCAGATAATAAGCAGCGTGACCCCTCGATGGACTCTGTCAAGGTTGTGATTGATGTCGAGCAG
AACTGTATCAGTGTGTTCAACAATGGAGATGGAGTTCCGGTTGAGGTTCATCAAGAAGAGAAGGTTTATGTGCCGGAGTTGATCTTTGGACACTTGTTGACTAGTAGTAA
TTATGATGACACTGTGAAGAAAACCACCGGTGGACGAAATGGCTACGGTGCGAAACTTACGAATATTTTTTCCACTGAATTTGTGATCGAGACGGCTGATGGAAAACGCC
TGAAGAAGTATAAGCAGTTATCCTGCTTAAGCATTGATCTTCTATGCTTGAATCCTTTCTCTCCGCTGAGCCTCATTAAAATAGTTAGACTCCTGCATGTCATTTTCCCC
TTCTTGAATGTGGCTTCCCGTTACCCATGTAAGAAACAACTTTCGAAGTTCTTTGAGGTGTTCTCTGATAACATGGGGAAGAAATCCGAGCCGATCATAACAAAGTGCAA
GGAGAGTGATAATTGGACCAAGGTGACTTTTAAGCCAGACTTGGCAAAGTTTAACATGACTCATCTTGAAGATGATGTTGTTGCACTGATGAAAAAGAGAGTGTTGGATT
TGGCTGGATGCCTTGGAAAGACCGTGAAGGTTGAGCTGAATGGGCAAAGAGTGCCTGTGAAATCGTTTCAAGATTATGTAGATCTCTATCTCAAATCGGCTTCTGCATTC
TCGACAGAACCTCCAAAAAGGTATCACATTAAGCCTAATGAGAGATGGGAAATCGTGGTGACCTTAAGTGAGGGGCAGTTCCAACAGGTCAGCTTTGTGAATGGGATTGC
AACTATCAAGGGTGGGACTCATGTTGATTACATCACTAATCAAATAGCAAATTATGTGATGACGGTTGTAAATAAGAAGAACAAAAATGCTAATGTGAAGGCCCACAATG
TGAAGAGCTATTTGTGGGTTTTTATCAACGCTCTCATTGATAATCCTGCCTTCGACTCCCAAACCAAGGAAACTTTGACAATTCGTCAAAGCAGTTTTGGTTGTGCATGC
GAACTTTCACCAGAGTTTTTGAAGAATGTGGCCACAAAATCTGGAATTATGGACAGCGTTCTCTCGTGGGTTAATTTCAAGCAAAGCAAAGACCTGAAGAAAACTGATGG
AGCAAAAACAGAAAAGATTAGTGGTATCGAAAAGTTGGAGGATGCCAATTGCGCTGGAGGGAAAAACTCGGAAAAATGTACTTTGATTTTGACAGAAGGAGATTCAGCCA
AGGCCCTTGCAATGGCTGGGCTCGGTGTAGTGGGACGAGACTTCTATGGCGTATTCCCACTAAGAGGTAAATTGCTCAATGTGAGGGAAGCGAGTAGCAAACAAATCATG
GAGAATAAAGAAATCCAGTACATCAAGCAAATTCTTGGACTTCAGCAAGGGAAGGAATACAGCAATGCTAAGGCTTTGAGATATGGTCATTTGATGATTATGACTGATCA
GGATCATGATGGTTCGCACATTAAAGGGCTCTTGATCAACTTTATTCATTCTTTCTGGCCTACTCTTCTAAGAGTACCGTCTTTCTTGGTTGAGTTCATAACACCTATTG
TCAAGGCTACTCATAGGAATGGAACTGTTTTGTCATTCTACACCATGCCTGAGTATGAGTCTTGGAAAGAGAGCTTGAGGGGCAATGCAAGTGGCTGGTCAATCAAGTAC
TATAAGGGGTTGGGAACAAGCACATCGAAAGAAGGAAGAGAGTACTTTGAACAACTGACAAAGCATAAGAAAGATTTTATTTGGCAAGATGACCATGATGGAGAGGCCAT
TGAACTTGCCTTCAGTAAGAAGAAGATTGAAGAGAGGAAGAATTGGCTTCGTCAATTTGAGCCTGGTACCCATCTAGATCAAACAGAAAAATTGATAAAATACAGTGACT
TTGTCAACAAGGAGCTTATATTATTTTCAATGGCGGATTTACAAAGGTCTATTCCCTCAATGGTTGATGGCCTCAAGCCTGGCCAGAGGAAGATCCTTTACTGTTCTTTC
AAGAGGAACTTCATCAAAGAAGCAAAAGTTTCTCAATTTTCTGGTTACGTATCTGAGCATTCTGCTTATCATCATGGTGAGCAGAGTCTTGCTAGCACCATCATTGGAAT
GGCACAGGACTTTGTTGGCAGCAACAACATTAATCTTCTTATGCCAAACGGACAGTTTGGCACTCGGAACCATGGAGGCAAAGATCATGCAAGTTCTAGGTACATTTACA
CTAAGCTCTCAAATGTTACACGGTTCCTTTTCCCGAAAGACGATGACAAGCTTCTTAACTACTTAAATGAAGATGGCCAGTCAATTGAACCAACCTGGTACATGCCTATC
ATACCAACGGTTCTTGTCAATGGAAGTGAAGGAATTGGAACTGGTTGGAGTTCATACATTCCAAATTATAATCCTAGAGATATCATTAGAAATGTCAGACGCTTGTTGGA
TGGTGAAACAATGGTGCCAATGGATCCTTGGTATAGAGGTTTTTCAGGAACTATAGAGAAAACTGCCACTAAAGAAGGAGGTACTAGTTACACTGTTAGTGGAATTATAG
AGGAAGTCAGCGATACAACATTGAGAATAATTGAACTGCCCGTTCGCAAATGGACTAATGATTATAAGGAATTCCTTGATTCTGTAACGAGAGTTGCAGCAAGGAATGAC
AAAGACAAAGAAAAAGCAGCGAAGGATCCTTTTATTGAGCAAGCTGATCACCACAGTGATGACAAAATTGTGTCCATTGATGTTCACTTGACAGAGGAGAACATGATACT
GGCCATGCAGGAGGGTTTGAAGAAGAAATTCAAATTAACAAATACTATCAGCACCAGCAACATGCATCTCTTTGATGCAAATGGCGTGATTAAGAAATATGACACTCCAG
AACAAATTCTTGAGGAATTTTTCCCCCTTAGACTTGAATTCTATGAGAAAAGAAAGAGAAATCTTTTGGAGAACCTTGAAATGGAGTTGCTCAAATTGGAAAACAAGGTG
AGGTTTATCCTTGCTGTTGTGAATGGAGAGATAATAGTAAGCAATAGAAGAAGAGTTGATTTATTCCATGAGCTTCAAGCGAAAGGCTTTACACCGTTTCCAAAGAAGAC
TAAATCTGTTGAACCGGAGGTTGCTGGGGCATCTAATGAAACAGAGGAAACAGAGGAGAGTCCAGAAGTAAAAGGGGAACGGGTTAGTGATTACGAGTATCTACTTGCTC
TAGCAATTGGAACCTTGACCATTGAGAAGGTTCAGGAGCTATGCAACGATAGGGACAAGCTCAAAGGGGAAGTGGAAGATCTGAGGAAGGCAACCCCCAAGTCTTTGTGG
CTAAAAGATCTTGATTCTCTTGAGAAGGAACTTGATGAGATGGATAGAAATGATGCTCAGGCTGAGGAGGTAAGGAAACAACAGAGAATCAAAGCAAATAATGATGTAAA
GCCAAGGATCTCAAGGAATGCACCAAAAGCTCCACGTAACAGTAAGAAAACTAGCAATTCAGAAGCCGTCACGGAAAGTATGGACACAACATCTAGTTCTACAACAGCTG
AAGTTGCAAGTAACGCAGTGGTGAAGCCTAAAGGCAAAGCAGCAGCTCCAAGAAAAGCTCCTGCCAAAAAGGGTAAAGCTGCAGTTGTCAACGATGATGATGAAGATGAC
GACGACGAAGTGCTCGAGCTTAAAGATCGTCTTGCTGCCTATAAAATTGAATCATCTCCAGATCGTTCTGAAGTTGATGATCAAGTAACAAGGATCTCAATTCTTGTTCA
TTTTCCAGTTTCAGCCATGGAAACTGAAGTGCCGCAAGTACAACCGGCCAAGAAGAAAGAACCCAGCAAGAGAGCACCTGCCAAGAAGAAAACTACTGCAAAGTCTGCAC
AGAATTCTGACAACGACGATAGCGACGACGAAGACTTCGAAATAAAGGAGATAGCCCCTCCAGCAGCCAAGAAGGGAGGAGGAGGAAGAAAGGCAGCTGCGGCCAAAACA
ACCAAGCCCCCTGCAGCAGCCAAGAAGCGAGAGCCGGCGGCGAAGTTGGGGCAGAAACTGATAACTCAAATGCTGGAGCCGGCGGAGAACTCTGGCATCTCGCCGGAGAA
GAAAGTGAGGAAGATAAGAGCATCACCTTTCAACAAGAAAAGTGGCTCCATATTGGGAAGAGTTGGGATAGAAGAAGTAGAGGAAGAAGAAGAAGAAGGTGGAAATGAAG
ATAAGATTATGGGCTCTGCTTCTTCTGAGACGACTGAAGAAACCGCCGGAGTTGCTCCGGCGAGAGGAAGATCTCAGAGGGCTAAAAGAACTCAGGTGAGATATGTGGTT
AGTGATTCAGAGAGTGAGCCAGCTTCTGAGGATTCAGACTTCGATGAAAAAGATGCAGACTTTGATGAAGATTGA

mRNA sequence

Show/hide mRNA sequence

Protein sequence

Show/hide protein sequence

MAVEKKRPLQNSNAANVDQIPTGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQ
NCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQLSCLSIDLLCLNPFSPLSLIKIVRLLHVIFP
FLNVASRYPCKKQLSKFFEVFSDNMGKKSEPIITKCKESDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASAF
STEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGCAC
ELSPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIM
ENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPTLLRVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKY
YKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQTEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILYCSF
KRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPI
IPTVLVNGSEGIGTGWSSYIPNYNPRDIIRNVRRLLDGETMVPMDPWYRGFSGTIEKTATKEGGTSYTVSGIIEEVSDTTLRIIELPVRKWTNDYKEFLDSVTRVAARND
KDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMILAMQEGLKKKFKLTNTISTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKV
RFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETEETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEDLRKATPKSLW
LKDLDSLEKELDEMDRNDAQAEEVRKQQRIKANNDVKPRISRNAPKAPRNSKKTSNSEAVTESMDTTSSSTTAEVASNAVVKPKGKAAAPRKAPAKKGKAAVVNDDDEDD
DDEVLELKDRLAAYKIESSPDRSEVDDQVTRISILVHFPVSAMETEVPQVQPAKKKEPSKRAPAKKKTTAKSAQNSDNDDSDDEDFEIKEIAPPAAKKGGGGRKAAAAKT
TKPPAAAKKREPAAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRVGIEEVEEEEEEGGNEDKIMGSASSETTEETAGVAPARGRSQRAKRTQVRYVV
SDSESEPASEDSDFDEKDADFDED

Spg038958 (gene) of Sponge gourd (cylindrica) v1 genome