CuGenDBv2

Gene ID	Tan0002712
Organism	Trichosanthes anguina (Snake gourd v1)
Description	dCTP pyrophosphatase 1
Genome location	LG05:75310595..75312028
RNA-Seq Expression	Tan0002712
Synteny	Tan0002712
Gene Ontology terms	GO:0006253 - dCTP catabolic process (biological process) GO:0042262 - DNA protection (biological process) GO:0005829 - cytosol (cellular component) GO:0000287 - magnesium ion binding (molecular function) GO:0047840 - dCTP diphosphatase activity (molecular function)
InterPro domains	IPR025984 - dCTP pyrophosphatase 1

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6607469.1 dCTP pyrophosphatase 1, partial [Cucurbita argyrosperma subsp. sororia]

1.3e-47

88.14

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Query:  MEKMNKLDVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGRAAL
        MEK NK DV LRELSERVAEFARVRGWDKYH+PRNLLLAL VGEVGE+SEIFQWKGEV RGLPNWSAADKE L EELSDVLLYLV+LADVCG+DLGRAAL
Subjt:  MEKMNKLDVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGRAAL

Query:  SKILKNATKYPDLIPHKQ
        SKILKNATKYP L PH+Q
Subjt:  SKILKNATKYPDLIPHKQ

XP_022137081.1 dCTP pyrophosphatase 1-like [Momordica charantia]

3.5e-45

84.17

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Query:  MEKMNKL--DVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGRA
        MEK N    DVSL EL +RVAEFA  RGWDK+HTPRNLLLAL VGEVGELSEIFQWKGEV RGLPNWSA DKEHLEEELSDVLLYLV+LADVCGLDLGRA
Subjt:  MEKMNKL--DVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGRA

Query:  ALSKILKNATKYPDLIPHKQ
        ALSKILKNA KYP LIPH++
Subjt:  ALSKILKNATKYPDLIPHKQ

XP_022948897.1 dCTP pyrophosphatase 1-like [Cucurbita moschata]

1.7e-47

86.89

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Query:  MEKQMEKMNKLDVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLG
        MEKQMEK NK DV LRELSERVAEFARVRGWDKYH+ RNLLLAL VGEVGE+SEIFQWKGEV RGLPNWSAADKE L EELSDVLLYLV+LADVC +DLG
Subjt:  MEKQMEKMNKLDVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLG

Query:  RAALSKILKNATKYPDLIPHKQ
        RAALSKILKNATKYP L PH+Q
Subjt:  RAALSKILKNATKYPDLIPHKQ

XP_022998186.1 dCTP pyrophosphatase 1-like [Cucurbita maxima]

7.3e-51

86.4

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Query:  MEKQMEKMNKLDVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLG
        M+K+MEK NK DV L+ELSERVAEFARVRGWDKYH+PRNLLLAL VGEVGE++EIFQWKGEV RGLPNWSAADKEHL EELSDVLLYLV+LADVCG+DLG
Subjt:  MEKQMEKMNKLDVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLG

Query:  RAALSKILKNATKYPDLIPHKQIQP
        RAALSKILKNATKYP L PH+QIQP
Subjt:  RAALSKILKNATKYPDLIPHKQIQP

XP_038895217.1 dCTP pyrophosphatase 1-like [Benincasa hispida]

6.4e-47

81.6

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Query:  KQMEKM-NKLDVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGR
        ++MEK  NK +VSLRELSERVAEF RVRGWDKYHTPRNLLLAL VGEVGE+SEIFQWKGEVG+GLP+WSAADKEHLE+ELSDV LYL++LADVCGLDL +
Subjt:  KQMEKM-NKLDVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGR

Query:  AALSKILKNATKYPDLIPH-KQIQP
        AALSKILKNA+KYP   PH +QIQP
Subjt:  AALSKILKNATKYPDLIPH-KQIQP

TrEMBL top hits

e value

%identity

Alignment

A0A1R3HEG6 dCTP pyrophosphatase 1

1.4e-44

78.86

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Query:  MEKQMEKMN--KLDVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLD
        MEK  E  N    DVSL+EL +R+AEFA VRGW+KYH+PRNLLLAL VGEVGELSEIFQWKGEV +GLPNWSA DKEHLE+ELSDVLLYLVQLADVCGLD
Subjt:  MEKQMEKMN--KLDVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLD

Query:  LGRAALSKILKNATKYPDLIPHK
        LGRAALSKILKNA KYP ++  K
Subjt:  LGRAALSKILKNATKYPDLIPHK

A0A1R3KCG6 dCTP pyrophosphatase 1

1.4e-44

78.86

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Query:  MEKQMEKMN--KLDVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLD
        MEK  E  N    DVSL+EL +R+AEFA VRGW+KYH+PRNLLLAL VGEVGELSEIFQWKGEV +GLPNWSA DKEHLE+ELSDVLLYLVQLADVCGLD
Subjt:  MEKQMEKMN--KLDVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLD

Query:  LGRAALSKILKNATKYPDLIPHK
        LGRAALSKILKNA KYP ++  K
Subjt:  LGRAALSKILKNATKYPDLIPHK

A0A6J1C5G1 dCTP pyrophosphatase 1

1.7e-45

84.17

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Query:  MEKMNKL--DVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGRA
        MEK N    DVSL EL +RVAEFA  RGWDK+HTPRNLLLAL VGEVGELSEIFQWKGEV RGLPNWSA DKEHLEEELSDVLLYLV+LADVCGLDLGRA
Subjt:  MEKMNKL--DVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGRA

Query:  ALSKILKNATKYPDLIPHKQ
        ALSKILKNA KYP LIPH++
Subjt:  ALSKILKNATKYPDLIPHKQ

A0A6J1GAI3 dCTP pyrophosphatase 1

8.2e-48

86.89

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Query:  MEKQMEKMNKLDVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLG
        MEKQMEK NK DV LRELSERVAEFARVRGWDKYH+ RNLLLAL VGEVGE+SEIFQWKGEV RGLPNWSAADKE L EELSDVLLYLV+LADVC +DLG
Subjt:  MEKQMEKMNKLDVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLG

Query:  RAALSKILKNATKYPDLIPHKQ
        RAALSKILKNATKYP L PH+Q
Subjt:  RAALSKILKNATKYPDLIPHKQ

A0A6J1K9K2 dCTP pyrophosphatase 1

3.5e-51

86.4

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Query:  MEKQMEKMNKLDVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLG
        M+K+MEK NK DV L+ELSERVAEFARVRGWDKYH+PRNLLLAL VGEVGE++EIFQWKGEV RGLPNWSAADKEHL EELSDVLLYLV+LADVCG+DLG
Subjt:  MEKQMEKMNKLDVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLG

Query:  RAALSKILKNATKYPDLIPHKQIQP
        RAALSKILKNATKYP L PH+QIQP
Subjt:  RAALSKILKNATKYPDLIPHKQIQP

SwissProt top hits

e value

%identity

Alignment

Q32KY6 dCTP pyrophosphatase 1

1.3e-21

50.98

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Query:  SLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGRAALSKILKNATK
        +L ++    AEFA  R W+++H PRNLLLAL VGEVGEL+E+FQWK +   G   WS  ++  L+EELSD+L+YLV LA  C +DL +A L K+  N  +
Subjt:  SLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGRAALSKILKNATK

Query:  YP
        YP
Subjt:  YP

Q91VC0 dCTP pyrophosphatase 1

1.5e-22

51.96

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Query:  SLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGRAALSKILKNATK
        +L ++    AEFA  R W+++H PRNLLLAL VGEVGEL+E+FQWK +   G   W   ++  L+EELSDVL+YLV LA  C +DL RA +SK+  N  +
Subjt:  SLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGRAALSKILKNATK

Query:  YP
        YP
Subjt:  YP

Q9H773 dCTP pyrophosphatase 1

7.4e-22

52.94

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Query:  SLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGRAALSKILKNATK
        +L ++    AEFA  R W+++H PRNLLLAL VGEVGEL+E+FQWK +   G   WS  ++  L+EELSDVL+YLV LA  C +DL  A LSK+  N  +
Subjt:  SLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGRAALSKILKNATK

Query:  YP
        YP
Subjt:  YP

Q9QY93 dCTP pyrophosphatase 1

5.7e-22

50.98

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Query:  SLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGRAALSKILKNATK
        +L ++    AEFA  R W+++H PRNLLLAL VGEVGEL+E+FQWK +   G   W   ++  L+EELSDVL+YLV LA  C +DL +A +SK+  N  +
Subjt:  SLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGRAALSKILKNATK

Query:  YP
        YP
Subjt:  YP

Arabidopsis top hits

e value

%identity

Alignment

AT3G25400.1 CONTAINS InterPro DOMAIN/s: NTP Pyrophosphohydrolase MazG-related, RS21-C6 (InterPro:IPR011394), EAR (InterPro:IPR009039), NTP pyrophosphohydrolase MazG, putative catalytic core (InterPro:IPR004518); Has 1123 Blast hits to 1121 proteins in 452 species: Archae - 22; Bacteria - 753; Metazoa - 81; Fungi - 3; Plants - 83; Viruses - 0; Other Eukaryotes - 181 (source: NCBI BLink).

1.4e-36

66.97

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Query:  VSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGRAALSKILKNAT
        VSL+ LS+++ +FA+ R W+KYH+PRNLLLA+ VGEVGELSEIFQWKGEV RG P+W   +K HL EELSDVLLYLV+L+D CG+DLG+AAL KI  NA 
Subjt:  VSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGRAALSKILKNAT

Query:  KYPDLIPHK
        KYP  +P K
Subjt:  KYPDLIPHK

Sequences

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CDS sequence

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ATGGAAAAGCAAATGGAGAAGATGAACAAATTAGACGTTTCTCTTAGAGAACTAAGTGAGAGAGTGGCGGAATTCGCTCGAGTTAGAGGTTGGGATAAGTATCACACTCC
TAGAAATCTCCTTCTCGCCCTTGAGGTGGGAGAAGTAGGGGAGCTATCAGAAATATTCCAATGGAAGGGAGAAGTAGGGAGGGGGCTGCCCAACTGGTCGGCGGCCGACA
AGGAGCATTTGGAAGAGGAGCTTTCCGACGTCTTACTTTATTTGGTTCAACTTGCAGATGTTTGTGGGCTTGATCTTGGTCGGGCTGCCCTTTCCAAGATCCTTAAAAAT
GCCACTAAATACCCTGATCTCATTCCTCACAAACAAATTCAACCCTAA

mRNA sequence

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AATTCTTCTCTTGGTGGTTTGGTCTTTAAATTGATGAGAAGTAATTGAAAAAAAAAAGAAGAGAGAAATGGAAAAGCAAATGGAGAAGATGAACAAATTAGACGTTTCTC
TTAGAGAACTAAGTGAGAGAGTGGCGGAATTCGCTCGAGTTAGAGGTTGGGATAAGTATCACACTCCTAGAAATCTCCTTCTCGCCCTTGAGGTGGGAGAAGTAGGGGAG
CTATCAGAAATATTCCAATGGAAGGGAGAAGTAGGGAGGGGGCTGCCCAACTGGTCGGCGGCCGACAAGGAGCATTTGGAAGAGGAGCTTTCCGACGTCTTACTTTATTT
GGTTCAACTTGCAGATGTTTGTGGGCTTGATCTTGGTCGGGCTGCCCTTTCCAAGATCCTTAAAAATGCCACTAAATACCCTGATCTCATTCCTCACAAACAAATTCAAC
CCTAAAACAAATTTCAATTACTCATCTTTCTCACCATATTATATTATATCATATAAATATATATTTTATCTACTAGCTTTCTTAAGGTTCTATTGCATCTGCCTCTTATA
ATTTTTATATATCAATTCAATGCTACCAAAATATAATTGGTGGATGTCTAATTTCGAATGCTTACGGCATGTTTGGGAGTGATTTTGGAGTGACCAAAATCA

Protein sequence

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MEKQMEKMNKLDVSLRELSERVAEFARVRGWDKYHTPRNLLLALEVGEVGELSEIFQWKGEVGRGLPNWSAADKEHLEEELSDVLLYLVQLADVCGLDLGRAALSKILKN
ATKYPDLIPHKQIQP

Tan0002712 (gene) of Snake gourd v1 genome