CuGenDBv2

Gene ID	Tan0002806
Organism	Trichosanthes anguina (Snake gourd v1)
Description	11-beta-hydroxysteroid dehydrogenase 1B-like
Genome location	LG05:81867689..81873310
RNA-Seq Expression	Tan0002806
Synteny	Tan0002806
Gene Ontology terms	GO:0008643 - carbohydrate transport (biological process) GO:0016021 - integral component of membrane (cellular component) GO:0016491 - oxidoreductase activity (molecular function) GO:0051119 - sugar transmembrane transporter activity (molecular function)
InterPro domains	IPR002347 - Short-chain dehydrogenase/reductase SDR IPR036291 - NAD(P)-binding domain superfamily

Homology

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GenBank top hits

e value

%identity

Alignment

KAG7012327.1 11-beta-hydroxysteroid dehydrogenase 1B, partial [Cucurbita argyrosperma subsp. argyrosperma]

3.5e-131

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        MELI SFLNLVAP FT V+LG LLP YVVFKYF S VRGLFSEDV GKVVLITGASSGIGE+LAYEYAKRGAQLALVARRE+ LEE A+AARYYGSP+VI
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM------------------------------AAIKSMFETLRVEVAP
        TI  DVSEL DCRRIIDDTMNHFG+LDHLVNNAGI NMTLFE+I DITSFK+IM                              AA++S FETLRVE++P
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM------------------------------AAIKSMFETLRVEVAP

Query:  EIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPEVVEWCYRIFVYTRPGSS
        EIGIT+VTPGFVESE+TKGKALYS   MEVH DVRDALVGAIPVETA ACAKAIVRS C+GDRYLTEPSW+NA YYLKAFCPEVVEWCYRI VYT PG+S
Subjt:  EIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPEVVEWCYRIFVYTRPGSS

Query:  PAEAPNKLMLDLTGAKNVMYPPSIH
         AEA NK +LDLTGAK  MYPPSIH
Subjt:  PAEAPNKLMLDLTGAKNVMYPPSIH

XP_004153123.1 11-beta-hydroxysteroid dehydrogenase 1B [Cucumis sativus]

4.6e-131

70.89

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        MELI SFLNLV+P  TFV+LGF LPPYVV KYFL  VRG+F+EDVAGKVVLITGASSGIGEHLAY+YA+RGA+LALV RR++PL EVAD ARYYGSPDVI
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------
        TIPADVS+L+D RRII DT+NHFG+LDHLVNNAG+ NMTLFE++ DITSF QIM                                              
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------

Query:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE
         AA+KSMFETLRVE+AP+IGITIVTPGFVESELTKGKALYS   MEVH DVRDAL+GAIPVET EACAKAIVRS CRGDRYLTEPSW+N+VYYLK FCPE
Subjt:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE

Query:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVEAE
        V+EWCYRIF+YTRPGSS AEAP+K +LD TGAKNVMYPPSIH  E E
Subjt:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVEAE

XP_008439964.1 PREDICTED: 11-beta-hydroxysteroid dehydrogenase 1B-like isoform X2 [Cucumis melo]

8.3e-133

71.76

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        M LIHSFLNLV+P  TFV+LGFLLPPYVVFKYFL  VRG+FSEDVAGKVVLITGASSGIGEHLAY+YA+RGA+LALV RRE PL EVAD ARYYGSPD+I
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------
        TIPADVS L+DCRRIID+T+NHFG+LDHLVNNAG+ NMTLFE+I DITS  QIM                                              
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------

Query:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE
         AA++SMFETLRVE+AP+IGITIVTPGFVESELTKGKALYS  T+EVH DVRDAL+GAIPVET EACAKAIVRS CRGDRYLTEPSW+N+VYY+K FCPE
Subjt:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE

Query:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVEAE
        V+EW YRIFVYTRPG+S AEA NK MLD TGAKNVMYPPSIH VE E
Subjt:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVEAE

XP_022955312.1 11-beta-hydroxysteroid dehydrogenase 1B-like isoform X2 [Cucurbita moschata]

1.7e-130

72.17

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        MELI SFLNLVAP FT V+LG LLP YV+FKYF S VRGLFSEDVAGKVVLITGASSGIGE+LAYEYAKRGAQLALVARRE+ LEE A+AARYYGSP+VI
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------
        TI  DVS+L DCRRIIDDTMNHFG+LDHLVNNAGI NMTLFE+I DITSFKQIM                                              
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------

Query:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE
         AA++S FETLRVE++PEIGIT+VTPGFVESE+TKGKALYS   MEVH DVRD LVGAIPVETA ACAKAIVRS CRGDRYLTEPSW+NAVYYLKA CPE
Subjt:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE

Query:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVE
        VVEWCYRI VYT PG+S AEA NK +LDLTGAK  MYPPSIH VE
Subjt:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVE

XP_038893820.1 11-beta-hydroxysteroid dehydrogenase A-like isoform X2 [Benincasa hispida]

1.3e-133

72.05

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        MELI SFLNLVAP  TFV+LGFLLP +V FKYFLSFVR +FSED+ GKVVLITGASSGIGEHLAYEYA RGAQLALV RRE PLEEVA+ ARYYGSPDVI
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------
        TIPAD+S L+DCRRIID T+NHFG+LDHLVNNAGI NMTLFE+I DITSF QIM                                              
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------

Query:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE
         AA++SMFETLRVE+APEIGITIVTPGFVESELTKGKALYSQ T+EVH DVRDAL+GAIPVET EACAKAIVRS CRGDRYLTEPSW+N +YYLK FCPE
Subjt:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE

Query:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVEAE
        V+EWCYRIFVYTRPG+S AEAP+K  +D+TGAKNVMYPPSIH  E E
Subjt:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVEAE

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LUG2 Uncharacterized protein

1.8e-133

74.77

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        MELI SFLNLV+P  TFV+LGF LPPYVV KYFL  VRG+F+EDVAGKVVLITGASSGIGEHLAY+YA+RGA+LALV RR++PL EVAD ARYYGSPDVI
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM-----------------------------AAIKSMFETLRVEVAPE
        TIPADVS+L+D RRII DT+NHFG+LDHLVNNAG+ NMTLFE++ DITSF QIM                             AA+KSMFETLRVE+AP+
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM-----------------------------AAIKSMFETLRVEVAPE

Query:  IGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPEVVEWCYRIFVYTRPGSSP
        IGITIVTPGFVESELTKGKALYS   MEVH DVRDAL+GAIPVET EACAKAIVRS CRGDRYLTEPSW+N+VYYLK FCPEV+EWCYRIF+YTRPGSS 
Subjt:  IGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPEVVEWCYRIFVYTRPGSSP

Query:  AEAPNKLMLDLTGAKNVMYPPSIHEVEAE
        AEAP+K +LD TGAKNVMYPPSIH  E E
Subjt:  AEAPNKLMLDLTGAKNVMYPPSIHEVEAE

A0A1S3AZL2 11-beta-hydroxysteroid dehydrogenase 1B-like isoform X2

4.0e-133

71.76

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        M LIHSFLNLV+P  TFV+LGFLLPPYVVFKYFL  VRG+FSEDVAGKVVLITGASSGIGEHLAY+YA+RGA+LALV RRE PL EVAD ARYYGSPD+I
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------
        TIPADVS L+DCRRIID+T+NHFG+LDHLVNNAG+ NMTLFE+I DITS  QIM                                              
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------

Query:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE
         AA++SMFETLRVE+AP+IGITIVTPGFVESELTKGKALYS  T+EVH DVRDAL+GAIPVET EACAKAIVRS CRGDRYLTEPSW+N+VYY+K FCPE
Subjt:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE

Query:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVEAE
        V+EW YRIFVYTRPG+S AEA NK MLD TGAKNVMYPPSIH VE E
Subjt:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVEAE

A0A1S4DSY4 11-beta-hydroxysteroid dehydrogenase 1B-like isoform X1

3.0e-128

66.13

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        M LIHSFLNLV+P  TFV+LGFLLPPYVVFKYFL  VRG+FSEDVAGKVVLITGASSGIGEHLAY+YA+RGA+LALV RRE PL EVAD ARYYGSPD+I
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGK----------------------------LDHLVNNAGITNMTLFEKITDITSFKQIM------------------
        TIPADVS L+DCRRIID+T+NHFG+                            +DHLVNNAG+ NMTLFE+I DITS  QIM                  
Subjt:  TIPADVSELEDCRRIIDDTMNHFGK----------------------------LDHLVNNAGITNMTLFEKITDITSFKQIM------------------

Query:  -----------------------------AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIV
                                     AA++SMFETLRVE+AP+IGITIVTPGFVESELTKGKALYS  T+EVH DVRDAL+GAIPVET EACAKAIV
Subjt:  -----------------------------AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIV

Query:  RSGCRGDRYLTEPSWFNAVYYLKAFCPEVVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVEAE
        RS CRGDRYLTEPSW+N+VYY+K FCPEV+EW YRIFVYTRPG+S AEA NK MLD TGAKNVMYPPSIH VE E
Subjt:  RSGCRGDRYLTEPSWFNAVYYLKAFCPEVVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVEAE

A0A6J1GT78 11-beta-hydroxysteroid dehydrogenase 1B-like isoform X2

8.4e-131

72.17

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        MELI SFLNLVAP FT V+LG LLP YV+FKYF S VRGLFSEDVAGKVVLITGASSGIGE+LAYEYAKRGAQLALVARRE+ LEE A+AARYYGSP+VI
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------
        TI  DVS+L DCRRIIDDTMNHFG+LDHLVNNAGI NMTLFE+I DITSFKQIM                                              
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------

Query:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE
         AA++S FETLRVE++PEIGIT+VTPGFVESE+TKGKALYS   MEVH DVRD LVGAIPVETA ACAKAIVRS CRGDRYLTEPSW+NAVYYLKA CPE
Subjt:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE

Query:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVE
        VVEWCYRI VYT PG+S AEA NK +LDLTGAK  MYPPSIH VE
Subjt:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVE

A0A6J1K142 11-beta-hydroxysteroid dehydrogenase 1B-like isoform X2

4.2e-130

71.88

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        MELI SFLNLVAP FT V+LG LLP YVVFKYF S VRGLFSEDV GKVVLITGASSGIGE+LAYEYAKRGAQLALVARRE  LEE A+AARYYGSP+VI
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------
        TI  DVSEL DCRRIIDDTMNHFG+LDHLVNNAGI NMTLFE+I DITSFKQIM                                              
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------

Query:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE
         AA++S FETLRVE++PEIGIT+VTPGFVESE+T+GKALYS   MEVH DVRDALVGAIPV+TA ACAKAIVRS CRGDRYLTEPSW+NA YYLKAFCPE
Subjt:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE

Query:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVE
        VVEWCYRI VYT PG+S AEA NK +LDLTGAK  MYPPSIH V+
Subjt:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVE

SwissProt top hits

e value

%identity

Alignment

A7LB60 11-beta-hydroxysteroid dehydrogenase A

2.0e-89

50.72

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        M+LIH+FLNLVAP FTF  L   LPPY   K+ +S +  L SE+VAGKVV ITGASSGIGE+LAYEYAKRGA LAL ARRE  L +VAD AR+ GSPDVI
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------
         + ADVS+ EDC R+ID T+NHFG+LDHLVNNA I+  TLFE+  DI++ + IM                                              
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------

Query:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE
         AA+ S++ETLRVEV  EIGITIVTPG++ESE+TKGK L +Q  ++V  D+RD  V A+PV +   CA++I++S  RGDR LT PSWF   Y +K  CPE
Subjt:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE

Query:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVEAEVE
        ++EW +R+   T PG+  ++A +K +LD TGAKN+ YPPSI   + + +
Subjt:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVEAEVE

P0DKC5 11-beta-hydroxysteroid dehydrogenase 1A

2.2e-83

48.12

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        MELI+ FLNL AP FTF  L F LPP+  FK+  S    +FSE++ GKVVLITGASSGIGE LAYEYA RGA LAL ARR+N LEEVA+ AR  GSP+V+
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------
        T+ ADVS+ +DCRRI+DDT+ HFG+LDHLVNNAG+T +++FE I DIT  K ++                                              
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------

Query:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE
         AA+ S FET+R+E+  ++ ITIVTPG++ESELT+GK    +  + V+ D+RD  VG  PV +A  CAK+IV   CR  RY+TEPSWF   Y  K  CPE
Subjt:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE

Query:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVE
        ++EW  R+   T  G S   A NK ++D+ G ++ +YP SI   E
Subjt:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVE

P0DKC6 11-beta-hydroxysteroid dehydrogenase 1B

2.2e-83

48.12

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        MELI+ FLNL AP FTF  L F LPP+  FK+  S    +FSE++ GKVVLITGASSGIGE LAYEYA RGA LAL ARR+N LEEVA+ AR  GSP+V+
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------
        T+ ADVS+ +DCRRI+DDT+ HFG+LDHLVNNAG+T +++FE I DIT  K ++                                              
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------

Query:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE
         AA+ S FET+R+E+  ++ ITIVTPG++ESELT+GK    +  + V+ D+RD  VG  PV +A  CAK+IV   CR  RY+TEPSWF   Y  K  CPE
Subjt:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE

Query:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVE
        ++EW  R+   T  G S   A NK ++D+ G ++ +YP SI   E
Subjt:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVE

Q93W57 11-beta-hydroxysteroid dehydrogenase A

1.3e-88

49.28

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        M+LIH+FLNL+AP FTF  L F LPP+ +FK+FLS +  LFSEDVAGKVV+ITGASSGIGE LAYEYAKRGA L L ARRE  L+EVA+ AR  GSPDV+
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------
         + ADVS+ EDCR+++D TMN FG+LDHLVNNAGI ++++ E++ DIT +++ M                                              
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------

Query:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE
         AAI   FETLRVE  P+IGIT+VTPGF+ESELT+GK  Y+     +  D+RD  V   P+   E+ A++IVRS  RG+RY+TEP+WF   Y+ K FCPE
Subjt:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE

Query:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVE
        V+EW +R+     PG    E   K +LD TG K+++YP ++   E
Subjt:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVE

Q9LUE4 11-beta-hydroxysteroid dehydrogenase-like 6

4.2e-63

41.54

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        M+ I+  +N + P  T   L    P Y   K  +S  R LFSE+VAGKVV+ITGA+SGIGE LAYEY KRGA LALV  R  PL  VA  A  YGSP+V+
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------
         + ADVS+L+DC R I  T+ HFG+LDHLV NAG+  +  F  I D++     M                                              
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------

Query:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE
         AA+ + +ETLR E   +IG+TIV PG V+SE+++GK +     + V  ++RD  +  +PVE+AE CAKAI+RS CRGDRYL EP W   V  LK FC E
Subjt:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE

Query:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMY
          EW  R  +  RP     EA +  +LD+  A N  +
Subjt:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMY

Arabidopsis top hits

e value

%identity

Alignment

AT3G47350.1 hydroxysteroid dehydrogenase 2

7.4e-55

39.62

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        M+++H+ LN + P  T ++   L  P+ +F   +S ++ L  E+V GKVVLITGASSGIGEH+AYEYAK+GA+LALVARR++ LE VA+ +R  GS DVI
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------
         IP DVS +EDC++ ID+T++HFGKLDHL+NNAG+    +FE  T I     IM                                              
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------

Query:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELT--KGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFC
         AA+   FETLRVE++P+I ITI  PGF+ +++T  + K +Y                  I  E+   CAKAI R   RG+ Y+ EPSW   ++ +K  C
Subjt:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELT--KGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFC

Query:  PEVVEWC--YRIFVYTRP
        PE+V++   Y    Y +P
Subjt:  PEVVEWC--YRIFVYTRP

AT3G47360.1 hydroxysteroid dehydrogenase 3

7.0e-53

39.87

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        M+++ + LNL+ P  T + L    P Y++ K  L   + L  E+VA KVVLITGASSGIGEH+AYEYAK+GA LALVARR + LE VA+ +R  GS +VI
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------
         IP DVS +EDC++ ID+T+ HFGKLDHL+NNAG+    LFE  T I     IM                                              
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------

Query:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE
         AA+   FETLR+E++P+I ITIV PG V +++T              H +       I  E+   CAKAI R   RG+ Y+ EPSW   ++ +K  CPE
Subjt:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE

Query:  VVEW--CYRIFVYTRP
        +V++   Y    Y +P
Subjt:  VVEW--CYRIFVYTRP

AT5G50600.1 hydroxysteroid dehydrogenase 1

1.5e-84

48.12

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        MELI+ FLNL AP FTF  L F LPP+  FK+  S    +FSE++ GKVVLITGASSGIGE LAYEYA RGA LAL ARR+N LEEVA+ AR  GSP+V+
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------
        T+ ADVS+ +DCRRI+DDT+ HFG+LDHLVNNAG+T +++FE I DIT  K ++                                              
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------

Query:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE
         AA+ S FET+R+E+  ++ ITIVTPG++ESELT+GK    +  + V+ D+RD  VG  PV +A  CAK+IV   CR  RY+TEPSWF   Y  K  CPE
Subjt:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE

Query:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVE
        ++EW  R+   T  G S   A NK ++D+ G ++ +YP SI   E
Subjt:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVE

AT5G50700.1 hydroxysteroid dehydrogenase 1

1.5e-84

48.12

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        MELI+ FLNL AP FTF  L F LPP+  FK+  S    +FSE++ GKVVLITGASSGIGE LAYEYA RGA LAL ARR+N LEEVA+ AR  GSP+V+
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------
        T+ ADVS+ +DCRRI+DDT+ HFG+LDHLVNNAG+T +++FE I DIT  K ++                                              
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------

Query:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE
         AA+ S FET+R+E+  ++ ITIVTPG++ESELT+GK    +  + V+ D+RD  VG  PV +A  CAK+IV   CR  RY+TEPSWF   Y  K  CPE
Subjt:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE

Query:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVE
        ++EW  R+   T  G S   A NK ++D+ G ++ +YP SI   E
Subjt:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVE

AT5G50770.1 hydroxysteroid dehydrogenase 6

3.0e-64

41.54

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Query:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI
        M+ I+  +N + P  T   L    P Y   K  +S  R LFSE+VAGKVV+ITGA+SGIGE LAYEY KRGA LALV  R  PL  VA  A  YGSP+V+
Subjt:  MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVI

Query:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------
         + ADVS+L+DC R I  T+ HFG+LDHLV NAG+  +  F  I D++     M                                              
Subjt:  TIPADVSELEDCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIM----------------------------------------------

Query:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE
         AA+ + +ETLR E   +IG+TIV PG V+SE+++GK +     + V  ++RD  +  +PVE+AE CAKAI+RS CRGDRYL EP W   V  LK FC E
Subjt:  -AAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEACAKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPE

Query:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMY
          EW  R  +  RP     EA +  +LD+  A N  +
Subjt:  VVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMY

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGGAACTGATTCACAGCTTCCTGAATTTGGTGGCTCCGACCTTCACCTTCGTCACTCTCGGCTTTTTGCTGCCGCCTTACGTGGTTTTCAAGTATTTCTTGTCTTTCGT
TAGAGGTCTATTTAGCGAAGATGTTGCCGGAAAAGTCGTTCTCATCACCGGCGCTTCCTCCGGCATCGGAGAGCATTTGGCATACGAATACGCGAAGAGAGGAGCCCAAT
TAGCTCTGGTAGCTAGACGAGAGAACCCACTTGAGGAAGTTGCAGACGCAGCTCGTTATTATGGCTCCCCTGATGTTATAACCATTCCAGCCGACGTTTCCGAGCTCGAA
GACTGTCGACGAATCATCGACGACACAATGAATCACTTCGGCAAATTGGACCATTTGGTGAACAATGCTGGCATCACCAACATGACCCTGTTTGAAAAAATCACCGATAT
CACTTCCTTCAAACAAATAATGGCGGCGATTAAGAGCATGTTTGAGACATTGAGAGTGGAAGTGGCGCCGGAGATTGGGATCACAATTGTGACGCCTGGTTTTGTTGAGT
CTGAATTGACTAAAGGGAAGGCCTTGTATTCTCAAGCTACAATGGAAGTTCATCACGATGTTAGAGATGCTCTAGTGGGTGCTATTCCGGTGGAGACGGCGGAGGCGTGC
GCAAAAGCCATCGTGAGGAGCGGGTGCCGCGGCGACCGGTACTTGACGGAGCCGTCGTGGTTCAATGCCGTGTATTACCTGAAGGCATTTTGCCCGGAGGTGGTGGAGTG
GTGCTACCGCATATTTGTGTACACAAGGCCCGGTTCCTCCCCGGCCGAGGCGCCCAACAAACTGATGTTGGACCTGACCGGAGCCAAGAATGTTATGTATCCTCCTTCCA
TTCACGAGGTCGAGGCCGAGGTCGAGGCCGGCTAA

mRNA sequence

Show/hide mRNA sequence

Protein sequence

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MELIHSFLNLVAPTFTFVTLGFLLPPYVVFKYFLSFVRGLFSEDVAGKVVLITGASSGIGEHLAYEYAKRGAQLALVARRENPLEEVADAARYYGSPDVITIPADVSELE
DCRRIIDDTMNHFGKLDHLVNNAGITNMTLFEKITDITSFKQIMAAIKSMFETLRVEVAPEIGITIVTPGFVESELTKGKALYSQATMEVHHDVRDALVGAIPVETAEAC
AKAIVRSGCRGDRYLTEPSWFNAVYYLKAFCPEVVEWCYRIFVYTRPGSSPAEAPNKLMLDLTGAKNVMYPPSIHEVEAEVEAG

Tan0002806 (gene) of Snake gourd v1 genome