CuGenDBv2

Gene ID	Tan0004007
Organism	Trichosanthes anguina (Snake gourd v1)
Description	Mediator of RNA polymerase II transcription subunit 21
Genome location	LG07:9288917..9293087
RNA-Seq Expression	Tan0004007
Synteny	Tan0004007
Gene Ontology terms	GO:0006357 - regulation of transcription by RNA polymerase II (biological process) GO:0050832 - defense response to fungus (biological process) GO:0016592 - mediator complex (cellular component) GO:0043078 - polar nucleus (cellular component) GO:0003712 - transcription coregulator activity (molecular function)
InterPro domains	IPR021384 - Mediator complex, subunit Med21 IPR037212 - Mediator complex, subunit Med7/Med21-like

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6605829.1 Mediator of RNA polymerase II transcription subunit 21, partial [Cucurbita argyrosperma subsp. sororia]

5.1e-61

96.97

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Query:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
        LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTED ANFAEQPKLMSA LVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
Subjt:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL

Query:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD
        QKQLEAAEKELK+VQELFSQVADNC+NLKKAD
Subjt:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD

XP_022153730.1 mediator of RNA polymerase II transcription subunit 21 [Momordica charantia]

9.0e-58

94.7

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Query:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
        LQEQVNTIAALAFNTFGTLQRDAPPVRLS NYPEPP  EPTED AN AEQPKLMSA LVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
Subjt:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL

Query:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD
        QKQLEAAEKELK+VQELFSQVADNCLNLKKAD
Subjt:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD

XP_022958635.1 mediator of RNA polymerase II transcription subunit 21 [Cucurbita moschata]

3.0e-61

97.73

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Query:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
        LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTED ANFAEQPKLMSA LVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
Subjt:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL

Query:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD
        QKQLEAAEKELK+VQELFSQVADNCLNLKKAD
Subjt:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD

XP_023532119.1 mediator of RNA polymerase II transcription subunit 21 [Cucurbita pepo subsp. pepo]

1.9e-60

96.21

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Query:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
        LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPT+D ANF EQPKLMSA LVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
Subjt:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL

Query:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD
        QKQLEAAEKELK+VQELFSQVADNCLNLKKAD
Subjt:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD

XP_038893979.1 mediator of RNA polymerase II transcription subunit 21-like [Benincasa hispida]

5.8e-57

92.42

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Query:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
        LQEQVN IAALAFNTFGTLQRDAPPVRLSPNYPEPP HEPTED AN AEQPKLMSA LVKAAKQFD LVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
Subjt:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL

Query:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD
        QKQL+AAE+EL +VQELFSQVADNCLNLKKAD
Subjt:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KZ00 Mediator of RNA polymerase II transcription subunit 21

3.1e-56

91.67

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Query:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
        LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPP  EPTED A  AEQPKLMSA LVKAAKQFD LVAALPLSDGGEEEQLKRIAELQAEND VGQEL
Subjt:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL

Query:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD
        QKQL+AAEKEL +VQELFSQVADNCLNLKKAD
Subjt:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD

A0A5D3DEB7 Mediator of RNA polymerase II transcription subunit 21

1.8e-56

91.67

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Query:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
        LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPP  EPTEDGA  AEQPKLMSA LVKAAKQFD LVAALPLSDGGEEEQLKRIAELQAEND VGQEL
Subjt:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL

Query:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD
        QKQL+AAE+EL +VQELFSQVADNCLNLKKAD
Subjt:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD

A0A6J1DHM9 Mediator of RNA polymerase II transcription subunit 21

4.3e-58

94.7

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Query:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
        LQEQVNTIAALAFNTFGTLQRDAPPVRLS NYPEPP  EPTED AN AEQPKLMSA LVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
Subjt:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL

Query:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD
        QKQLEAAEKELK+VQELFSQVADNCLNLKKAD
Subjt:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD

A0A6J1H2M0 Mediator of RNA polymerase II transcription subunit 21

1.4e-61

97.73

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Query:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
        LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTED ANFAEQPKLMSA LVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
Subjt:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL

Query:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD
        QKQLEAAEKELK+VQELFSQVADNCLNLKKAD
Subjt:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD

A0A6J1K432 Mediator of RNA polymerase II transcription subunit 21

1.4e-61

97.73

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Query:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
        LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTED ANFAEQPKLMSA LVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL
Subjt:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQEL

Query:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD
        QKQLEAAEKELK+VQELFSQVADNCLNLKKAD
Subjt:  QKQLEAAEKELKEVQELFSQVADNCLNLKKAD

SwissProt top hits

e value

%identity

Alignment

C0LU16 Mediator of RNA polymerase II transcription subunit 21

5.1e-48

78.2

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Query:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEP-TEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQE
        LQEQVNTIAA+ FN FGTLQRDAPPV+LSPNYPEPP     T+D   F EQPK +SA LVKAAKQFD LVAALPLS+GGE  QLKRIAELQ END VGQE
Subjt:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEP-TEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQE

Query:  LQKQLEAAEKELKEVQELFSQVADNCLNLKKAD
        LQKQLEAAEKELK+VQELF Q ADNCLN+KK +
Subjt:  LQKQLEAAEKELKEVQELFSQVADNCLNLKKAD

Q7ZTI5 Mediator of RNA polymerase II transcription subunit 21

3.5e-04

26.62

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Query:  MINKFNILQEQVNTIAALAFNTFGTLQRDAPPVRLS---PNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQ
        M ++   LQ+ VN++A    N  G LQ+ APP   S       +  P  PTE      E  +L +A + + AK  DVL+ +LP  +     Q   + +L+
Subjt:  MINKFNILQEQVNTIAALAFNTFGTLQRDAPPVRLS---PNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQ

Query:  AENDAVGQELQKQLEAAEKELKEVQELFSQVADNCLNLK
         EN      L++ +   +  L+++Q   + +A + L  +
Subjt:  AENDAVGQELQKQLEAAEKELKEVQELFSQVADNCLNLK

Arabidopsis top hits

e value

%identity

Alignment

AT4G04780.1 mediator 21

3.6e-49

78.2

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Query:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEP-TEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQE
        LQEQVNTIAA+ FN FGTLQRDAPPV+LSPNYPEPP     T+D   F EQPK +SA LVKAAKQFD LVAALPLS+GGE  QLKRIAELQ END VGQE
Subjt:  LQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEP-TEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQE

Query:  LQKQLEAAEKELKEVQELFSQVADNCLNLKKAD
        LQKQLEAAEKELK+VQELF Q ADNCLN+KK +
Subjt:  LQKQLEAAEKELKEVQELFSQVADNCLNLKKAD

Sequences

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CDS sequence

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ATGATAAACAAATTTAACATCTTACAAGAACAAGTTAACACAATTGCTGCTTTAGCTTTCAACACATTTGGGACATTACAAAGAGATGCTCCTCCAGTTCGTTTATCCCC
TAATTACCCCGAACCACCTCCTCACGAACCTACAGAGGACGGTGCAAATTTCGCAGAGCAGCCCAAGCTAATGAGTGCCACTTTGGTGAAAGCTGCTAAGCAGTTTGATG
TATTGGTTGCTGCATTGCCTCTATCTGATGGAGGGGAAGAAGAGCAGTTGAAAAGGATTGCAGAACTACAGGCTGAGAACGACGCTGTAGGTCAGGAACTTCAAAAGCAG
CTAGAAGCAGCAGAGAAAGAATTAAAAGAGGTTCAGGAGCTTTTCAGCCAAGTTGCAGATAATTGCTTGAACTTAAAGAAAGCAGACTGA

mRNA sequence

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CTTCATTTTACACCCTCGTGCTCCACCTTCACGTCGACTCCTCCTCCTCCGTGTCAGCCATTCAGTGTCGCCACAGCCCCTCTCCGTTCAGAGCTGCCGCCGCCGTCTTT
CTTGGGCTCGTGCCGCCGTAGCCTCCGTCCTAGCGGGTGCTCTCCCAAGGGTTTCTATGCGCCCAATTGAGAACGGGAATTGGTTTATCCTTTCATGATAAACAAATTTA
ACATCTTACAAGAACAAGTTAACACAATTGCTGCTTTAGCTTTCAACACATTTGGGACATTACAAAGAGATGCTCCTCCAGTTCGTTTATCCCCTAATTACCCCGAACCA
CCTCCTCACGAACCTACAGAGGACGGTGCAAATTTCGCAGAGCAGCCCAAGCTAATGAGTGCCACTTTGGTGAAAGCTGCTAAGCAGTTTGATGTATTGGTTGCTGCATT
GCCTCTATCTGATGGAGGGGAAGAAGAGCAGTTGAAAAGGATTGCAGAACTACAGGCTGAGAACGACGCTGTAGGTCAGGAACTTCAAAAGCAGCTAGAAGCAGCAGAGA
AAGAATTAAAAGAGGTTCAGGAGCTTTTCAGCCAAGTTGCAGATAATTGCTTGAACTTAAAGAAAGCAGACTGAAAGATTGCAAGGATAGAGTAGCTCAAATGCATTCCT
CTCCTCCTAATCTAATGCAACTTAGAACAGATGCATTAATTTTCTGCGGCACTTTCTCCATTTTCTCATCGCTTTTTAGCCTATATTCTGTATTTGCAAATATAGCCCTT
TAAAATTTCTTTTTTGCTAATTTCCTTATAGCCTTCGTATATTCTCTAGCTTATAAATGATAAATGTATTACTTGCCATTAAGTCTATTAGTCATTTAATAATAGACACA
TATATCATTAGGCCCTCGAGGGATGGTGAACCATTGGTAAGGACTTGGGATCTCTTGGTCATATTGGTTTAGATGGTTTAAATTCGAGCCATTGAGTAAACTTAATAAAT
AAAAATTCTTGA

Protein sequence

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MINKFNILQEQVNTIAALAFNTFGTLQRDAPPVRLSPNYPEPPPHEPTEDGANFAEQPKLMSATLVKAAKQFDVLVAALPLSDGGEEEQLKRIAELQAENDAVGQELQKQ
LEAAEKELKEVQELFSQVADNCLNLKKAD

Tan0004007 (gene) of Snake gourd v1 genome