CuGenDBv2

Gene ID	Tan0005552
Organism	Trichosanthes anguina (Snake gourd v1)
Description	DNA topoisomerase 2
Genome location	LG04:82883414..82890459
RNA-Seq Expression	Tan0005552
Synteny	Tan0005552
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0043231 - intracellular membrane-bounded organelle (cellular component) GO:0003677 - DNA binding (molecular function) GO:0046872 - metal ion binding (molecular function) GO:0005524 - ATP binding (molecular function) GO:0003918 - DNA topoisomerase type II (ATP-hydrolyzing) activity (molecular function)
InterPro domains	IPR013506 - DNA topoisomerase, type IIA, subunit B, domain 2 IPR036890 - Histidine kinase/HSP90-like ATPase superfamily IPR034157 - DNA topoisomerase 2, TOPRIM domain IPR031660 - C-terminal associated domain of TOPRIM IPR020568 - Ribosomal protein S5 domain 2-type fold IPR018522 - DNA topoisomerase, type IIA, conserved site IPR014721 - Ribosomal protein S5 domain 2-type fold, subgroup IPR013760 - DNA topoisomerase, type IIA-like domain superfamily IPR013759 - DNA topoisomerase, type IIA, subunit B, C-terminal IPR013758 - DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta IPR013757 - Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily IPR006171 - TOPRIM domain IPR003594 - Histidine kinase/HSP90-like ATPase IPR002205 - DNA topoisomerase, type IIA, subunit A/C-terminal IPR001241 - DNA topoisomerase, type IIA IPR001154 - DNA topoisomerase II, eukaryotic-type

Homology

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GenBank top hits

e value

%identity

Alignment

KAG7018075.1 DNA topoisomerase 2 [Cucurbita argyrosperma subsp. argyrosperma]

0.0e+00

90.93

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Query:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNAANVD  PAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD
        S+KVVID EQN ISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDD EKKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVFSDNMGKKS+
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV
        PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ F  EPPKRYH++PNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV

Query:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        A KSGIMDSVLSWVNFKQSKDLKKTDG KTEKI+GIEKLEDANCAGG+NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYN++KALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKK EERK+WLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMAD QRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLA TIIGMAQD+VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS
        RFLFPKDDDKLLNYL+EDGQSIEPTWYMPIIPTVLVNG EGIGTGWS++IPNYNPRDIIRNVRRML+GE MLPMDPWYRGFSGTIEKTATKEGG+SYTVS
Subjt:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS

Query:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTS-KNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHL
        GIIEEVSDTTLRITELPVR+WTNDYK+FLDSVTR S KNDKDKEKAAKDPFIEQADHHSDDK+VSIDVHLTEENMILAMQEGLKKK KLTTT+STSNMHL
Subjt:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTS-KNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHL

Query:  FDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSE
        FDANGVIKKYD PEQILEEFFPLRLE++EKRK+NLLENLE ELLKLENKVRFILAVVNGEIIVSNR+RVDLFHELQ KGFTPFPKKTKSVEPE+AGAS+E
Subjt:  FDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSE

Query:  TDETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPK
        TDE EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE LRKATPKSLWLKDLD LEKELDEMDRNDAQ DEVRKQQRIK NND+KPK
Subjt:  TDETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPK

Query:  ISRNAPKAPRNSKKTSNSETVTESMD-TTSSSTTMEVASNAVVKPKGKAAAPRKAPAKK-GKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSA
        ISRNAPKAPRNSKKTSNSET+TESMD TTSSSTT EVA+N VVKPKGK AAPRKAPAKK GKAAV++D   DDDDEVLELKDRLAAYK+ESSP+ SEVSA
Subjt:  ISRNAPKAPRNSKKTSNSETVTESMD-TTSSSTTMEVASNAVVKPKGKAAAPRKAPAKK-GKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSA

Query:  METEVPQAQ-AAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKG--AKLGQKLITQMLEPAE
        METEVP+ Q AAKKKEPSKRA AKKKTTAKS QIS  DD+DD DFEIKEI PPAAKKGGG  RKAAANAKTTK      K+   A+LGQKLITQMLEP E
Subjt:  METEVPQAQ-AAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKG--AKLGQKLITQMLEPAE

Query:  NPGISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETT-EESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSD
        N GISPEKKVRKIR SPFNKKSGS+LGR   EEEEE EE       GNEGK+MGS SSETT EE A  P ARGRSQR NRTQVRYV+SDSDSEPV EDSD
Subjt:  NPGISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETT-EESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSD

Query:  FDEKDADFDED
        FDE +A+ DED
Subjt:  FDEKDADFDED

XP_022152631.1 DNA topoisomerase 2 isoform X1 [Momordica charantia]

0.0e+00

90.85

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Query:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNS  ANVD  PAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD
        SVKVVIDVEQNCISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEFVIETADGKR KKYKQVF DNMGKKS+
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV
        P+ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTF  EPPKRYH+KPNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV
        TLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGS CELTPEFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV

Query:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        A+KSGIMDSVLSWVNFKQSKDLKKTDG KTEKI+GIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYN+ K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQDDHDGEAIELAFSKKK EERK+WLR FEPGTHLDQT KLIKYSDFVNKELILFSMAD QRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPS+VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLA TIIGMAQD+VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS
        RFLFP+DDD+LLNYL+EDGQSIEPTWYMPIIPTVLVNG EGIGTGWS+++PNYNPRDII NV+R+LDGETM+PMDPWY+GFSG IEKTATKEGG SYTVS
Subjt:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS

Query:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHLF
        GIIEEVSDTTLRITELPVR+WTNDYKEFLDSVTR +  + DKEKAAKDPFIEQADHHSDDK+VSIDVHLTEENMILA+QEGLKKK KLTTT+STSNMHLF
Subjt:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHLF

Query:  DANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSET
        D+NGVIKKYD PEQILEEFFPLRLEYYEKRK NLLENLE ELL+LENKVRFILAVVNGEI+VSNR+RVDLFHELQAKGFTPFPKKTKSVEPE+AGAS+ET
Subjt:  DANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSET

Query:  DETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPKIS
        DE EESPE KGERVSDY YLLALAIGTLTIEKVQELCNDRD+LKGEVE LRKATPKSLWLKDLD+LEKELDEMDRNDAQ +EVRKQQRIKANNDVKPKIS
Subjt:  DETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPKIS

Query:  RN-APKAPRNSKKTSNSETVTESMDTTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAMET
        RN APKAPRNSKKT NSET+ ESMDTTSSSTTMEVASNAVVKPKGK AAPRKAPAKKGK    ND   DDDDEVLELKDRLAAYKI+SSPDRSEVSAMET
Subjt:  RN-APKAPRNSKKTSNSETVTESMDTTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAMET

Query:  EVPQ-AQAAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGA---KLGQKLITQMLEPAENP
        EVPQ   AAKKKEPSKRAPAKKKTTAKS QISDNDD+DD+DFEIKE+ PPAAKKGGG   + AANAKTTKPPAAA K+ A   KLGQKLITQML P +N 
Subjt:  EVPQ-AQAAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGA---KLGQKLITQMLEPAENP

Query:  GISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFDE
        GISPEKKVRK+RASPFNKKSGSILGR G      EEEEEE E  GNEGKIMGS SSET EESAGF PARGRSQRANRTQV+YV+SDSDS+PV E    D+
Subjt:  GISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFDE

Query:  KDADFDED
        KD DFD++
Subjt:  KDADFDED

XP_022152632.1 DNA topoisomerase 2 isoform X2 [Momordica charantia]

0.0e+00

90.72

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNS  ANVD  PAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD
        SVKVVIDVEQNCISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEFVIETADGKR KKYKQVF DNMGKKS+
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV
        P+ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTF  EPPKRYH+KPNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV
        TLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGS CELTPEFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV

Query:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        A+KSGIMDSVLSWVNFKQSKDLKKTDG KTEKI+GIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYN+ K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQDDHDGEAIELAFSKKK EERK+WLR FEPGTHLDQT KLIKYSDFVNKELILFSMAD QRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPS+VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLA TIIGMAQD+VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS
        RFLFP+DDD+LLNYL+EDGQSIEPTWYMPIIPTVLVNG EGIGTGWS+++PNYNPRDII NV+R+LDGETM+PMDPWY+GFSG IEKTATKEGG SYTVS
Subjt:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS

Query:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHLF
        GIIEEVSDTTLRITELPVR+WTNDYKEFLDSVTR +  + DKEKAAKDPFIEQADHHSDDK+VSIDVHLTEENMILA+QEGLKKK KLTTT+STSNMHLF
Subjt:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHLF

Query:  DANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSET
        D+NGVIKKYD PEQILEEFFPLRLEYYEKRK NLLENLE ELL+LENKVRFILAVVNGEI+VSNR+RVDLFHELQAKGFTPFPKKTKSVEPE+AGAS+ET
Subjt:  DANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSET

Query:  DETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPKIS
        DE EESPE KGERVSDY YLLALAIGTLTIEKVQELCNDRD+LKGEVE LRKATPKSLWLKDLD+LEKELDEMDRNDAQ +EVRKQQRIKANNDVKPKIS
Subjt:  DETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPKIS

Query:  RN-APKAPRNSKKTSNSETVTESMDTTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAMET
        RN APKAPRNSKKT NSET+ ESMDTTSSSTTMEVASNAVVKPKGK AAPRKAPAKKGK    ND   DDDDEVLELKDRLAAYKI+SSPDRSE  AMET
Subjt:  RN-APKAPRNSKKTSNSETVTESMDTTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAMET

Query:  EVPQ-AQAAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGA---KLGQKLITQMLEPAENP
        EVPQ   AAKKKEPSKRAPAKKKTTAKS QISDNDD+DD+DFEIKE+ PPAAKKGGG   + AANAKTTKPPAAA K+ A   KLGQKLITQML P +N 
Subjt:  EVPQ-AQAAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGA---KLGQKLITQMLEPAENP

Query:  GISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFDE
        GISPEKKVRK+RASPFNKKSGSILGR G      EEEEEE E  GNEGKIMGS SSET EESAGF PARGRSQRANRTQV+YV+SDSDS+PV E    D+
Subjt:  GISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFDE

Query:  KDADFDED
        KD DFD++
Subjt:  KDADFDED

XP_022935016.1 DNA topoisomerase 2 isoform X2 [Cucurbita moschata]

0.0e+00

90.98

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNAANVD  PAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD
        S+KVVID EQN ISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDD EKKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVFSDNMGKKS+
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV
        PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ F  EPPKRYH++PNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV

Query:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        A KSGIMDSVLSWVNFKQSKDLKKTDG KTEKI+GIEKLEDANCAGG+NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYN++KALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKK EERK+WLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMAD QRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLA TIIGMAQD+VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS
        RFLFPKDDDKLLNYL+EDGQSIEPTWYMPIIPTVLVNG EGIGTGWS++IPNYNPRDIIRNVRRML+GE MLPMDPWYRGFSGTIEKTATKEGG+SYTVS
Subjt:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS

Query:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTS-KNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHL
        GIIEEVSDTTLRITELPVR+WTNDYK+FLDSVTR S KNDKDKEKAAKDPFIEQADHHSDDK+VSIDVHLTEENMILAMQEGLKKK KLTTT+STSNMHL
Subjt:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTS-KNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHL

Query:  FDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSE
        FDANGVIKKYD PEQILEEFFPLRLE++EKRK+NLLENLE ELLKLENKVRFILAVVNGEIIVSNR+RVDLFHELQ KGFTPFPKKTKSVEPE+AGAS+E
Subjt:  FDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSE

Query:  TDETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPK
        TDE EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE LRKATPKSLWLKDLD LEKELDEMDRNDAQ DEVRKQQRIK NND+KPK
Subjt:  TDETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPK

Query:  ISRNAPKAPRNSKKTSNSETVTESMD-TTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAM
        ISRNAPKAPRNSKKTSNSET+TESMD TTSSSTT EVA+N VVKPKGK AAPRKAPAKKGK AV++D   DDDDEVLELKDRLAAYK+ESSP+ SEVSAM
Subjt:  ISRNAPKAPRNSKKTSNSETVTESMD-TTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAM

Query:  ETEVPQAQ-AAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLITQMLEPAENPG
        ETEVP+ Q AAKKKEPSKRA AKKKTTAKS QIS  DD+DD DFEIKEI PPAAKKGGG  RKAAANAKTTK      +  A+LGQKLITQMLEP EN G
Subjt:  ETEVPQAQ-AAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLITQMLEPAENPG

Query:  ISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETT-EESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFDE
        ISPEKKVRKIR SPFNKKSGS+LGR   EEEEE EE       GNEGK+MGS SSETT EE A  P ARGRSQR NRTQVRYV+SDSDSEPV EDSDFDE
Subjt:  ISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETT-EESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFDE

Query:  KDADFDED
         +A+ DED
Subjt:  KDADFDED

XP_023527823.1 DNA topoisomerase 2 isoform X3 [Cucurbita pepo subsp. pepo]

0.0e+00

90.85

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNAANVD  P GPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLW+YENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD
        S+KVVID EQN ISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDD EKKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVFSDNMGKKS+
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV
        PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ F  EPPKRYH++PNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV

Query:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        A KSGIMDSVLSWVNFKQSKDLKKTDG KTEKI+GIEKLEDANCAGG+NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYN++KALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKK EERK+WLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMAD QRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLA TIIGMAQD+VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS
        RFLFPKDDDKLLNYL+EDGQSIEPTWYMPIIPTVLVNG EGIGTGWS++IPNYNPRDIIRNVRRML+GE MLPMDPWYRGFSGTIEKTATKEGG+SYTVS
Subjt:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS

Query:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTS-KNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHL
        GIIEEVSDTTLRITELPVR+WTNDYK+FLDSVTR S KNDKDKEKAAKDPFIEQADHHSDDK+VSIDVHLTEENMILAMQEGLKKK KLTTT+STSNMHL
Subjt:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTS-KNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHL

Query:  FDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSE
        FDANGVIKKYD PEQILEEFFPLRLE++EKRK+NLLENLE ELLKLENKVRFILAVVNGEIIVSNR+RVDLFHELQ KGFTPFPKKTKSVEPE+AGAS+E
Subjt:  FDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSE

Query:  TDETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPK
        TDE EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE LRKATPKSLWLKDLD LEKELDEMDRNDAQ DEVRKQQRIK NNDVKPK
Subjt:  TDETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPK

Query:  ISRNAPKAPRNSKKTSNSETVTESMD-TTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAM
        ISRNAPKAPRNSKKTSNSET+TESMD TTSSSTT EVA+N VVKPKGK AAPRKAPAKKGKAAV++D   DDDDEVLELKDRLAAYK+ESSP+ SEVSAM
Subjt:  ISRNAPKAPRNSKKTSNSETVTESMD-TTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAM

Query:  ETEVPQAQ-AAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLITQMLEPAENPG
        ETEVP+ Q AAKKKEPSKRA AKKKTTAKS QIS  DD+D+ DFEIKEI PPAAKKGGG  RKAAANAKTTK      +  A+LGQKLITQMLEP EN G
Subjt:  ETEVPQAQ-AAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLITQMLEPAENPG

Query:  ISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAG-FPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFDE
        ISPEKKVRKIR SPFNKKSGS+LGR   EEEEE E        GNEGK+MGS SSETT+E  G  P ARGRSQR NRTQVRYV+SDSDSEPV EDSDFDE
Subjt:  ISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAG-FPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFDE

Query:  KDADFDED
         +AD DED
Subjt:  KDADFDED

TrEMBL top hits

e value

%identity

Alignment

A0A6J1DGT3 DNA topoisomerase 2

0.0e+00

90.72

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNS  ANVD  PAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD
        SVKVVIDVEQNCISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEFVIETADGKR KKYKQVF DNMGKKS+
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV
        P+ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTF  EPPKRYH+KPNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV
        TLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGS CELTPEFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV

Query:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        A+KSGIMDSVLSWVNFKQSKDLKKTDG KTEKI+GIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYN+ K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQDDHDGEAIELAFSKKK EERK+WLR FEPGTHLDQT KLIKYSDFVNKELILFSMAD QRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPS+VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLA TIIGMAQD+VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS
        RFLFP+DDD+LLNYL+EDGQSIEPTWYMPIIPTVLVNG EGIGTGWS+++PNYNPRDII NV+R+LDGETM+PMDPWY+GFSG IEKTATKEGG SYTVS
Subjt:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS

Query:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHLF
        GIIEEVSDTTLRITELPVR+WTNDYKEFLDSVTR +  + DKEKAAKDPFIEQADHHSDDK+VSIDVHLTEENMILA+QEGLKKK KLTTT+STSNMHLF
Subjt:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHLF

Query:  DANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSET
        D+NGVIKKYD PEQILEEFFPLRLEYYEKRK NLLENLE ELL+LENKVRFILAVVNGEI+VSNR+RVDLFHELQAKGFTPFPKKTKSVEPE+AGAS+ET
Subjt:  DANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSET

Query:  DETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPKIS
        DE EESPE KGERVSDY YLLALAIGTLTIEKVQELCNDRD+LKGEVE LRKATPKSLWLKDLD+LEKELDEMDRNDAQ +EVRKQQRIKANNDVKPKIS
Subjt:  DETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPKIS

Query:  RN-APKAPRNSKKTSNSETVTESMDTTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAMET
        RN APKAPRNSKKT NSET+ ESMDTTSSSTTMEVASNAVVKPKGK AAPRKAPAKKGK    ND   DDDDEVLELKDRLAAYKI+SSPDRSE  AMET
Subjt:  RN-APKAPRNSKKTSNSETVTESMDTTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAMET

Query:  EVPQ-AQAAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGA---KLGQKLITQMLEPAENP
        EVPQ   AAKKKEPSKRAPAKKKTTAKS QISDNDD+DD+DFEIKE+ PPAAKKGGG   + AANAKTTKPPAAA K+ A   KLGQKLITQML P +N 
Subjt:  EVPQ-AQAAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGA---KLGQKLITQMLEPAENP

Query:  GISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFDE
        GISPEKKVRK+RASPFNKKSGSILGR G      EEEEEE E  GNEGKIMGS SSET EESAGF PARGRSQRANRTQV+YV+SDSDS+PV E    D+
Subjt:  GISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFDE

Query:  KDADFDED
        KD DFD++
Subjt:  KDADFDED

A0A6J1DIB5 DNA topoisomerase 2

0.0e+00

90.85

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNS  ANVD  PAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD
        SVKVVIDVEQNCISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEFVIETADGKR KKYKQVF DNMGKKS+
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV
        P+ITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLD+AGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTF  EPPKRYH+KPNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV
        TLSEGQFQQVSFVN IATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGS CELTPEFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV

Query:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        A+KSGIMDSVLSWVNFKQSKDLKKTDG KTEKI+GIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYN+ K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDF+WQDDHDGEAIELAFSKKK EERK+WLR FEPGTHLDQT KLIKYSDFVNKELILFSMAD QRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPS+VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLA TIIGMAQD+VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS
        RFLFP+DDD+LLNYL+EDGQSIEPTWYMPIIPTVLVNG EGIGTGWS+++PNYNPRDII NV+R+LDGETM+PMDPWY+GFSG IEKTATKEGG SYTVS
Subjt:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS

Query:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHLF
        GIIEEVSDTTLRITELPVR+WTNDYKEFLDSVTR +  + DKEKAAKDPFIEQADHHSDDK+VSIDVHLTEENMILA+QEGLKKK KLTTT+STSNMHLF
Subjt:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHLF

Query:  DANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSET
        D+NGVIKKYD PEQILEEFFPLRLEYYEKRK NLLENLE ELL+LENKVRFILAVVNGEI+VSNR+RVDLFHELQAKGFTPFPKKTKSVEPE+AGAS+ET
Subjt:  DANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSET

Query:  DETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPKIS
        DE EESPE KGERVSDY YLLALAIGTLTIEKVQELCNDRD+LKGEVE LRKATPKSLWLKDLD+LEKELDEMDRNDAQ +EVRKQQRIKANNDVKPKIS
Subjt:  DETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPKIS

Query:  RN-APKAPRNSKKTSNSETVTESMDTTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAMET
        RN APKAPRNSKKT NSET+ ESMDTTSSSTTMEVASNAVVKPKGK AAPRKAPAKKGK    ND   DDDDEVLELKDRLAAYKI+SSPDRSEVSAMET
Subjt:  RN-APKAPRNSKKTSNSETVTESMDTTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAMET

Query:  EVPQ-AQAAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGA---KLGQKLITQMLEPAENP
        EVPQ   AAKKKEPSKRAPAKKKTTAKS QISDNDD+DD+DFEIKE+ PPAAKKGGG   + AANAKTTKPPAAA K+ A   KLGQKLITQML P +N 
Subjt:  EVPQ-AQAAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGA---KLGQKLITQMLEPAENP

Query:  GISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFDE
        GISPEKKVRK+RASPFNKKSGSILGR G      EEEEEE E  GNEGKIMGS SSET EESAGF PARGRSQRANRTQV+YV+SDSDS+PV E    D+
Subjt:  GISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFDE

Query:  KDADFDED
        KD DFD++
Subjt:  KDADFDED

A0A6J1F3D6 DNA topoisomerase 2

0.0e+00

90.98

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNAANVD  PAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD
        S+KVVID EQN ISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDD EKKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVFSDNMGKKS+
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV
        PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ F  EPPKRYH++PNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV

Query:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        A KSGIMDSVLSWVNFKQSKDLKKTDG KTEKI+GIEKLEDANCAGG+NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYN++KALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKK EERK+WLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMAD QRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLA TIIGMAQD+VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS
        RFLFPKDDDKLLNYL+EDGQSIEPTWYMPIIPTVLVNG EGIGTGWS++IPNYNPRDIIRNVRRML+GE MLPMDPWYRGFSGTIEKTATKEGG+SYTVS
Subjt:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS

Query:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTS-KNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHL
        GIIEEVSDTTLRITELPVR+WTNDYK+FLDSVTR S KNDKDKEKAAKDPFIEQADHHSDDK+VSIDVHLTEENMILAMQEGLKKK KLTTT+STSNMHL
Subjt:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTS-KNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHL

Query:  FDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSE
        FDANGVIKKYD PEQILEEFFPLRLE++EKRK+NLLENLE ELLKLENKVRFILAVVNGEIIVSNR+RVDLFHELQ KGFTPFPKKTKSVEPE+AGAS+E
Subjt:  FDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSE

Query:  TDETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPK
        TDE EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE LRKATPKSLWLKDLD LEKELDEMDRNDAQ DEVRKQQRIK NND+KPK
Subjt:  TDETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPK

Query:  ISRNAPKAPRNSKKTSNSETVTESMD-TTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAM
        ISRNAPKAPRNSKKTSNSET+TESMD TTSSSTT EVA+N VVKPKGK AAPRKAPAKKGK AV++D   DDDDEVLELKDRLAAYK+ESSP+ SEVSAM
Subjt:  ISRNAPKAPRNSKKTSNSETVTESMD-TTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAM

Query:  ETEVPQAQ-AAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLITQMLEPAENPG
        ETEVP+ Q AAKKKEPSKRA AKKKTTAKS QIS  DD+DD DFEIKEI PPAAKKGGG  RKAAANAKTTK      +  A+LGQKLITQMLEP EN G
Subjt:  ETEVPQAQ-AAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLITQMLEPAENPG

Query:  ISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETT-EESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFDE
        ISPEKKVRKIR SPFNKKSGS+LGR   EEEEE EE       GNEGK+MGS SSETT EE A  P ARGRSQR NRTQVRYV+SDSDSEPV EDSDFDE
Subjt:  ISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETT-EESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFDE

Query:  KDADFDED
         +A+ DED
Subjt:  KDADFDED

A0A6J1F9E0 DNA topoisomerase 2

0.0e+00

90.92

Show/hide

Query:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSNAANVD  PAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD
        S+KVVID EQN ISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDD EKKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVFSDNMGKKS+
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV
        PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ F  EPPKRYH++PNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV

Query:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        A KSGIMDSVLSWVNFKQSKDLKKTDG KTEKI+GIEKLEDANCAGG+NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYN++KALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKK EERK+WLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMAD QRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLA TIIGMAQD+VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS
        RFLFPKDDDKLLNYL+EDGQSIEPTWYMPIIPTVLVNG EGIGTGWS++IPNYNPRDIIRNVRRML+GE MLPMDPWYRGFSGTIEKTATKEGG+SYTVS
Subjt:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS

Query:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTS-KNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHL
        GIIEEVSDTTLRITELPVR+WTNDYK+FLDSVTR S KNDKDKEKAAKDPFIEQADHHSDDK+VSIDVHLTEENMILAMQEGLKKK KLTTT+STSNMHL
Subjt:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTS-KNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHL

Query:  FDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSE
        FDANGVIKKYD PEQILEEFFPLRLE++EKRK+NLLENLE ELLKLENKVRFILAVVNGEIIVSNR+RVDLFHELQ KGFTPFPKKTKSVEPE+AGAS+E
Subjt:  FDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSE

Query:  TDETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPK
        TDE EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE LRKATPKSLWLKDLD LEKELDEMDRNDAQ DEVRKQQRIK NND+KPK
Subjt:  TDETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPK

Query:  ISRNAPKAPRNSKKTSNSETVTESMD-TTSSSTTMEVASNAVVKPKGKAAAPRKAPAKK-GKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSA
        ISRNAPKAPRNSKKTSNSET+TESMD TTSSSTT EVA+N VVKPKGK AAPRKAPAKK GK AV++D   DDDDEVLELKDRLAAYK+ESSP+ SEVSA
Subjt:  ISRNAPKAPRNSKKTSNSETVTESMD-TTSSSTTMEVASNAVVKPKGKAAAPRKAPAKK-GKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSA

Query:  METEVPQAQ-AAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLITQMLEPAENP
        METEVP+ Q AAKKKEPSKRA AKKKTTAKS QIS  DD+DD DFEIKEI PPAAKKGGG  RKAAANAKTTK      +  A+LGQKLITQMLEP EN 
Subjt:  METEVPQAQ-AAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLITQMLEPAENP

Query:  GISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETT-EESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFD
        GISPEKKVRKIR SPFNKKSGS+LGR   EEEEE EE       GNEGK+MGS SSETT EE A  P ARGRSQR NRTQVRYV+SDSDSEPV EDSDFD
Subjt:  GISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETT-EESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFD

Query:  EKDADFDED
        E +A+ DED
Subjt:  EKDADFDED

A0A6J1J555 DNA topoisomerase 2

0.0e+00

90.92

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Query:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVE KRPLQNSNAANVD  PAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLW+YENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD
        S+KVVID EQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDD EKKTTGGRNGYGAKLTNIFSTEFVIETADG+RLKKYKQVFSDNMGKKS+
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV
        PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA+ F  EPPKRYH++PNERWEIVV
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVM VVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNV

Query:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        A KSGIMDSVLSWVNFKQSKDLKKTDG KTEKI+GIEKLEDANCAGG+NSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  AAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYN++KALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD+HDGEAIELAFSKKK EERK+WLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMAD QRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLA TIIGMAQD+VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS
        RFLFPKDDDKLLNYL+EDGQSIEPTWYMPIIPTVLVNG EGIGTGWS++IPNYNPRDIIRNVRRMLDGE MLPMDPWYRGFSGTIEKTATKEGG+SYTVS
Subjt:  RFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVS

Query:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTS-KNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHL
        GIIEEVSDTTLRITELPVR+WTNDYK+FLDSVTR S KNDKDKEKAAKDPFIEQADHHSDDK+VSI+VHLTEENMILAMQEGLKKK KLTTT+STSNMHL
Subjt:  GIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTS-KNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHL

Query:  FDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSE
        FDANGVIKKYD PEQILEEFFPLRLE++EKRK+NLLENLE ELLKLENKVRFILAVVNGEIIVSNR+RVDLFHELQ KGFTPFPKKTKSVEPE+AGAS+E
Subjt:  FDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSE

Query:  TDETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPK
        TDE EESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEVE LRKATPKSLWLKDLD LEKELDEMDRNDAQ DEVRKQQRIK NND+KPK
Subjt:  TDETEESPE-VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPK

Query:  ISRNAPKAPRNSKKTSNSETVTESMD-TTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAM
        ISRNAPKAPRNSKKTSNSET+TESMD  TSSSTT EVA+N VVKPKGK AAPRKAPAKKGKAAV++DD    DDEVLELKDRLAAYK+ESSP+ SEVSAM
Subjt:  ISRNAPKAPRNSKKTSNSETVTESMD-TTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAM

Query:  ETEVPQAQ-AAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLITQMLEPAENPG
        ETEVP+ Q AAKKKEPSKRA AKKKTTAKS QIS  DD+DD DFEIKEI PPAAKKGGG  RKAAANAKTTK      +  A+LGQKLITQMLEP EN G
Subjt:  ETEVPQAQ-AAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLITQMLEPAENPG

Query:  ISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETT-EESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFDE
        ISPEKKVRKIR SPFNKKSGS+LGR   EEEEE EE       GNEGK+MGS SSETT EE A  P ARGRSQR NRTQVRYV+SDSDSEPV EDSDFDE
Subjt:  ISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETT-EESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFDE

Query:  KDADFDED
         +AD DED
Subjt:  KDADFDED

SwissProt top hits

e value

%identity

Alignment

O24308 DNA topoisomerase 2

0.0e+00

63.18

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Query:  KKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKV
        +KRPLQ SNAAN+      P KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHR+V+YVPGLYKIFDEILVNAADNKQRDPSMDS+KV
Subjt:  KKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKV

Query:  VIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSDPIIT
         ID E N +SV+NNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADG+RLKKYKQVFS+NMG K +P+IT
Subjt:  VIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSDPIIT

Query:  KCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVVTLSE
        KCK  +NWTKVTFKPDL KF M +LE+DVVALMKKRVLD+AGC GKTVKVELNG  +  KSF+DY DL+LK A      P  R H K  +RWEI ++LS+
Subjt:  KCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVVTLSE

Query:  GQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNVAAKS
        GQFQQVSFVN IATIKGGTHVDYITNQI  Y+MN VNKK K+ANVKAH VK++LWVF+N+LIDNPAFDSQTKETLT RQ+SFGS C++    LK+V  KS
Subjt:  GQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNVAAKS

Query:  GIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKE
        GI+D++LSW +FKQSKDLKKTDGTKT+++ G  K EDAN AGGRNSEKCTLILTEGDSAKALAMAGL VVGRD YGVFPLRGKLLNVREASSKQI +N+E
Subjt:  GIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKE

Query:  IQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNAS
        IQ IK+ILGLQQ KEY + K+LRYGHLMIM DQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEF TP+++A+H N T+ SFY+MPEYE+WKE L  +A+
Subjt:  IQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNAS

Query:  GWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRSIPSM
         W IKYYKGLGTST +EGREYF  L +H+KDFIW D+ DG AIELAFSKKK E RK W+R FEPGT  D   KLI Y DFVNKELILFS AD        
Subjt:  GWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRSIPSM

Query:  VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLF
                   LF SFK+   KE KV+QF GYVSEHSAYHHGEQSLA TIIGMAQD+VGSNNINLL PNGQFGT N GGKDHAS+RYIYT+LS VTR LF
Subjt:  VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLF

Query:  PKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVSGIIE
         + DDKLL YL+EDG+SIEP WYMPIIP VLVNG EGIGTGWS++IPNYNPR+II NVRR+L+GE ++PMDPWY+GF GTIEK+A KEGG  Y V+G + 
Subjt:  PKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVSGIIE

Query:  EVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHLFDANG
        E+ + T RITELP+RKWT DYK+FL+S+T  + N        KDP IE    + DD  V I++ +  E +   +QEGL KK KLT+TISTSNMHLFDA G
Subjt:  EVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHLFDANG

Query:  VIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSETDETE
          KK+D PEQILEEFFPLRL+YYEK K+ +L NL   LL L+NKVRFIL VVNGEIIVSNRK+ +L  EL+ KGFTP P+K KS +P++AGA+ +  E +
Subjt:  VIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSETDETE

Query:  ESPE---------VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDV
        E  E         V+G    DY+ LL+L IGTLT+E VQ+L +++ + + E E L      SLWLKDLD  EK+LDE+D   A+ D  R  Q  K  N  
Subjt:  ESPE---------VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDV

Query:  KPKISRNAPKAPRNSKKTSNSETVTESMDTTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVS
          K ++  P+  +N+KK        +S++  + +++ME+  NAV     +AA P +    KG+AA   +  ++ +D++  L++RLAAY IESS ++S+  
Subjt:  KPKISRNAPKAPRNSKKTSNSETVTESMDTTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVS

Query:  AMETEVPQAQAAKKKEPSKRAPAKKKTTA---KSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAK------TTKPPAAAAKKGA----KLGQ
        AME+E  Q +AA KK+ +KR  AKKK++    +S   ++ +D DD+D + +E+   AA    GGR+ AA NAK        K PAA  K+        GQ
Subjt:  AMETEVPQAQAAKKKEPSKRAPAKKKTTA---KSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAK------TTKPPAAAAKKGA----KLGQ

Query:  KLITQMLEPAENPGISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVLSDS
        KL+T ML+PAE  G SPEKKVRK+R SPFNKKSGSILGRA   ++     +       + G    +  SE         PAR R QRANRTQ++Y LS+S
Subjt:  KLITQMLEPAENPGISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVLSDS

Query:  DSEPVVEDSDFDEKDADFDED
        +SE   EDSD D + +DF+ED
Subjt:  DSEPVVEDSDFDEKDADFDED

P08096 DNA topoisomerase 2

0.0e+00

45.55

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Query:  IEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVY--ENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVE
        +   YQ+ T  EH+L RPDTY+GSIE  T  +WV+  E +K+ +++VTYVPGLYKIFDEI+VNAADNK RDP+M+++KV +D E N IS++NNG G+P+E
Subjt:  IEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVY--ENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVE

Query:  VHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSDPIITKCKEGDNWTKVTFKPDLAKFN
        +H +EK+Y+PELIFG+LLTSSNYDD +KK TGGRNGYGAKL NIFSTEFV+ETAD +R+KKYKQ + DNM +KS+P+IT  K+ D +TK+TFKPDLAKF 
Subjt:  VHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSDPIITKCKEGDNWTKVTFKPDLAKFN

Query:  MTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHV
        M  ++DD+V+++K+R+ D+AG + +T KV LN +R+ +  F+ YV++YL S +    EPP+  +   N+RW++   +S+GQF+QVSFVN I+TI+GGTHV
Subjt:  MTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHV

Query:  DYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNVAAKSGIMDSVLSWVNFKQSKDLKKT
        +Y+ N+I + +  VV K+NK A VKA  +K+Y+ VF+N  I+NP+FDSQTKETLT + S+FGS C L+ +FLK +  KS +++ VL +   K  + L K 
Subjt:  DYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNVAAKSGIMDSVLSWVNFKQSKDLKKT

Query:  DGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNSSKA
        DG    +I G+ KLEDAN AG + S KC LILTEGDSAK+LA++GL VVGRD+YGVFPLRGKLLNVREAS  QI  NKEIQ IK+I+G    K Y   K 
Subjt:  DGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNSSKA

Query:  LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREY
        LRYGHLMIMTDQDHDGSHIKGL+IN++ S +PSLL++P FL++FITPI+K T  N  V +FYT+PEYE WKE+   N  GW IKYYKGLGTS   + + Y
Subjt:  LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREY

Query:  FEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRSIPSMVDGLKPGQRKILFCSFKRNFI
        F  L +H K F    + D E IE+AF+KKK + RK+WLR + PG ++D T   I   DF+N+ELI FSMADN RSIPS+VDGLKPGQRK+++  FKRN +
Subjt:  FEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRSIPSMVDGLKPGQRKILFCSFKRNFI

Query:  KEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLSEDGQSIEPT
         E KVS+ +GYV+  +AYHHGE S+  TI+ +AQ++VGSNNINLL+PNGQFGTR+ GGK+ ++SRY+ T LS + R LF  +DD+LLNY +++GQ IEP 
Subjt:  KEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLSEDGQSIEPT

Query:  WYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVSGIIEEVSDTTLRITELPVRKWTNDY
        +Y+PI+P VLVNG EGIGTGWSTFIPNYNP+DI  N+R ML+GE +  M PWYRGF G+I K A       Y +SGII ++ +  + ITELP+R WT D 
Subjt:  WYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSYTVSGIIEEVSDTTLRITELPVRKWTNDY

Query:  KEFLDS-VTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHLFDANGVIKKYDNPEQILEEFFPLRL
        KE+L++ +  T K  K         FI   + H  + +V  +V LTE  M  A+ E L+ K KL+ T +TSNM  FDA+G IKKYD+ E IL EF+ +RL
Subjt:  KEFLDS-VTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNMHLFDANGVIKKYDNPEQILEEFFPLRL

Query:  EYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPF--PKKTKSVEPEIAGASSETDETEESPEVKGERVSD-YEYLL
          Y++RK++++  LE    +  N+ RFI  ++ GE++VS +K+ DL  EL+ K F P   PKK   V+ E+  A +   E E+S +V  +  SD Y YLL
Subjt:  EYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPF--PKKTKSVEPEIAGASSETDETEESPEVKGERVSD-YEYLL

Query:  ALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLE----KELDEMDRNDAQVDEVRKQQRIKANNDVKPKISRNAPKAPRNSKKTSNSE
        ++ + +LT E+  EL   +D++  E++ L K TPK LWL DLD+ E    K +D++ R    ++E +  +        KP+      + PR    +S+S 
Subjt:  ALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLE----KELDEMDRNDAQVDEVRKQQRIKANNDVKPKISRNAPKAPRNSKKTSNSE

Query:  TVTESMDTTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAMETEVPQAQAAKKKEPSKRAP
         V +   + S  +T       +++      A  K P K              D  +++ +D      +E           E  + ++      +  K   
Subjt:  TVTESMDTTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAMETEVPQAQAAKKKEPSKRAP

Query:  AKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLITQMLEPAENPGISPEKKVRKIRASPFNKKSGS
             + K  Q  D++D   +    K +   AA   G GR+        T  P A     +     L+   L+P+          +   +AS  NK   +
Subjt:  AKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLITQMLEPAENPGISPEKKVRKIRASPFNKKSGS

Query:  ILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVL----SDSDSEPVVEDSDF----DEKDADFDE
            + ++++  E+++++  + G+      S ++    E +  P  +  ++RA  T    +      DS  EP ++D  F    DE   D+DE
Subjt:  ILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVL----SDSDSEPVVEDSDF----DEKDADFDE

P30182 DNA topoisomerase 2

0.0e+00

63.55

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Query:  KRPLQNSNAANVDQIPAGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNAANV + PA  +     KTIEEMYQKK+QLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R VTYVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNAANVDQIPAGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD
        SV+VVIDVEQN ISV N+G GVPVE+HQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADGKRLKKYKQVF +NMGKKS+
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS-TFTMEPPKRYHVKPNERWEIV
        P+ITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+ + T +P  R   K N+RWE+ 
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS-TFTMEPPKRYHVKPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKN
        V+LSEGQFQQVSFVN IATIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWVF+NALIDNPAFDSQTKETLT+RQSSFGS CEL+ +FLK 
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKN

Query:  VAAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DG KT ++  +EKL+DA  AGG+NS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VAAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE
        T NKEI+ +K+ILGL+Q  +Y +  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT K GT  VLSFY+MPEYE WKE
Subjt:  TENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADN
        SL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKK E RK+WL  + PG HLDQ    + YSDFVNKELILFSMAD 
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADN

Query:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLA  IIGMAQDYVGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSY
         VTR LFPKDDD LL+YL+EDGQ IEPTWYMPIIPTVLVNG EGIGTGWSTFIPNYNPR+I+ NVRR+L+GE+M+PMDPWYRGF GTIEKTA+KEGG +Y
Subjt:  NVTRFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSY

Query:  TVSGIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNM
        T++G+ EEV +TT+RITELP+R+W +DYK FL S+    K D         PF +    ++D+KSV  D+ L+EENM+ A QEG  KK KLTTTI+TSNM
Subjt:  TVSGIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNM

Query:  HLFDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAG--
        HLFD  GVIKKY  PEQILEEFF LR EYYEKRK+ +++N+E+ELLKLENK RFILAV++GEIIV+ RK+ D+  +L+ KGFTPFP+K +SVE  IAG  
Subjt:  HLFDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAG--

Query:  ---ASSETDETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEV--RKQQR
           A+ E +E    PE     +  S+Y+YLLA+AI +LTIEKV+EL  DRDK+   V  ++K TPKSLWL DL+SL+KEL+++D  DAQV +     Q++
Subjt:  ---ASSETDETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEV--RKQQR

Query:  IKANNDVKPKISRNAPKAPRNSKKTSNSETVTESMDTTSSSTTMEVASNA--VVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIE
        I+A +    K+ R APK P   K T  +   +ES  T +S + M+  +N   VVKPK +  A +K  A + +    +  A D D+ V E+         +
Subjt:  IKANNDVKPKISRNAPKAPRNSKKTSNSETVTESMDTTSSSTTMEVASNA--VVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIE

Query:  SSPDRSEVSAMETEVPQAQAAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLIT
             +     E E+        +     APA    TA++ +    DD DD+   + E+ P   KKGG   RK AA  K  KPPAA  K+G +      T
Subjt:  SSPDRSEVSAMETEVPQAQAAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLIT

Query:  QMLEPAENPGISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVLSDSDSEP
        ++L      G+SPEKKVRK+R+SPFNKKS S++ R      + +EEE  E V GN           ++E+S G   A  R QRANR ++ YVLSDS+SE 
Subjt:  QMLEPAENPGISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVLSDSDSEP

Query:  VVEDSDFDEKDADFDED
           DS+FD+ + D D++
Subjt:  VVEDSDFDEKDADFDED

Q55BP5 Probable DNA topoisomerase 2

0.0e+00

46.88

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Query:  EKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVK
        +K     N N        A   K+IEE+YQKK  L+ ILLRPDTY+GS E+  + LWV+E+ +MVHR V++VPG+YKIFDEILVNAADNKQR+ +M  +K
Subjt:  EKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVK

Query:  VVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSDPII
        VVID E+  ISV N+G G+P++VH E K+Y+PELIFG+LLTSS+YDD+EK+ TGGRNG+GAKL NIFST+F++E AD K  K YKQ F++NM  K DP I
Subjt:  VVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSDPII

Query:  TKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVVTLS
        T  +   ++TK+TF P+L +F M   +DD+VAL+ KRV D+AGC   T+KV LN + + ++SF+ Y++LY           PK Y+ K ++RWE+ VTLS
Subjt:  TKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVVTLS

Query:  -EGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNVA
         E QF QVSFVN I T+KGGTHV +  + I   +   VNKKNK +A++K   +K++L VF+N LI+NP FDSQTKETLT + SSFGS CE + +F+K V 
Subjt:  -EGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNVA

Query:  -AKSGIMDSVLSWVNFKQSKDLKK--TDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ
         +KSGI+ S+L +  FK    LK+  + G K  K++ I KL+DAN AGG  SE CTLILTEGDSAK+LA AG+ VVG+D YG FPL+GKLLNVR+ S+K 
Subjt:  -AKSGIMDSVLSWVNFKQSKDLKK--TDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ

Query:  ITENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKES
        +  N EI  I  ILGL+ GK Y +   LRYGHLMIMTDQDHDGSHIKGL+IN +H FWP+LLR+P FLVEFITPIVK    N   +SFYTMPE+  W+E+
Subjt:  ITENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKES

Query:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTG-KLIKYSDFVNKELILFSMADN
           N  GW +KYYKGLGTST  EG+EYF  L +HK DF W D+   + IELAFSK + ++RK W+ +   GT L+Q G K + YSDF+NKEL+LFS+AD 
Subjt:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTG-KLIKYSDFVNKELILFSMADN

Query:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        +RSIP++VDGLK   RK L+  FKRN  KE KV+Q  GYVSEHSAYHHGE SL  TI+GMAQ++VGSNNINLL P G +GTR  GGKD +S+RYI+T+L+
Subjt:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIE-KTATKEGGSS
        ++ R ++  DDD +L+ + +DG+ ++P +Y+P+IP +LVNG  GIGTGWS+ IPNYNPRD+I+N+R  +DG+ + P+ PWYRGF G+IE    +K  G  
Subjt:  NVTRFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIE-KTATKEGGSS

Query:  YTVSGIIEEVSDTTLRITELPVRKWTNDYKEFLDSV----TRTSKNDKDKEKA-------AKDPFIEQADHHSDDK----------------SVSIDVHL
        Y   GI +++SD    ITELP+  WT DY+E LD +    TR  K ++ ++KA       AK    +++    DD                 S    +H 
Subjt:  YTVSGIIEEVSDTTLRITELPVRKWTNDYKEFLDSV----TRTSKNDKDKEKA-------AKDPFIEQADHHSDDK----------------SVSIDVHL

Query:  TEENMILAMQEGLKKKLKLTTTISTSNMHLFDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVD
          + +    +  ++K  KL +TI+ +NM +FD  G I+++     + E FFPLR+++Y+ RK  L E L  E  +L NK RFILAVVN E+++SN K+VD
Subjt:  TEENMILAMQEGLKKKLKLTTTISTSNMHLFDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVD

Query:  LFHELQAKGFTPF------------PKKTKSVEPEIAGASSETDETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKS
        L ++L+   F                KK K+   E   A S  +E + + E + +    Y+YLL+L + +LT+E+V++L  +RD  K E + L     + 
Subjt:  LFHELQAKGFTPF------------PKKTKSVEPEIAGASSETDETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKS

Query:  LWLKDLDSLEKELDEMDRNDA----QVDEVRKQQRIKA---NNDVKPKISRNAPKAPRNS--KKTSNSETVTESM----------DTTSSSTTMEVASNA
        ++ +DLD+LEK LD+ D  D     Q + ++K+ + KA      +  K+ ++  +AP     K T    T T+S           DTTS+ST+   +SN 
Subjt:  LWLKDLDSLEKELDEMDRNDA----QVDEVRKQQRIKA---NNDVKPKISRNAPKAPRNS--KKTSNSETVTESM----------DTTSSSTTMEVASNA

Query:  VVKPKGKAAAPRK-APA-KKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAMETEVPQAQAAKKKEPSKRAPA----------KKKTTAKS
               A   +K  PA KK     ++ D++ DDD V+  K +    K     + S+ S  E++    Q +  + P KR+ A          KK TT+KS
Subjt:  VVKPKGKAAAPRK-APA-KKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAMETEVPQAQAAKKKEPSKRAPA----------KKKTTAKS

Query:  GQISDNDDTDDE
         ++ D+  +DDE
Subjt:  GQISDNDDTDDE

Q64511 DNA topoisomerase 2-beta

0.0e+00

52.89

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Query:  KKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYEND-KMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVK
        KK  L+ +N  +     +  K ++E +YQKKTQLEHILLRPDTY+GS+E  TQ +WVY+ D  M  R VT+VPGLYKIFDEILVNAADNKQRD +M  +K
Subjt:  KKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYEND-KMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVK

Query:  VVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSDPII
        V ID E N IS++NNG G+PV  H+ EKVYVP LIFG LLTSSNYDD EKK TGGRNGYGAKL NIFST+F +ETA  +    +KQ + +NM K S+  I
Subjt:  VVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSDPII

Query:  TKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVVTLS
         K  +G+++T +TF+PDL+KF M  L+ D+VALM +R  DLAG   K VKV  NG+++PV  F+ YVDLY+K     T    K  H   NERW++ +TLS
Subjt:  TKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVVTLS

Query:  EGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNVAA
        E  FQQ+SFVN IAT KGG HVDY+ +Q+ + ++ VV KKNK   +VK   VK+++WVFIN LI+NP FDSQTKE +T++  SFGS C+L+ +F K  A+
Subjt:  EGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNK-NANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNVAA

Query:  KSGIMDSVLSWVNFKQSKDL-KKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITE
          GI++S+L+WV FK    L KK    K  KI GI KL+DAN AGG++S +CTLILTEGDSAK+LA++GLGV+GRD YGVFPLRGK+LNVREAS KQI E
Subjt:  KSGIMDSVLSWVNFKQSKDL-KKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITE

Query:  NKEIQYIKQILGLQQGKEYN---SSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKES
        N EI  I +I+GLQ  K Y+   S K LRYG +MIMTDQD DGSHIKGLLINFIH  WPSLL+   FL EFITPIVKA+ KN   LSFY++PE++ WK+ 
Subjt:  NKEIQYIKQILGLQQGKEYN---SSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKES

Query:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFE-----------PGTHLDQTG-KLIKYSDFVN
        +  N   W IKYYKGLGTST+KE +EYF  + +H+  F +    D  AI LAFSKKK ++RK+WL  F            P   L  T  K + Y+DF+N
Subjt:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFE-----------PGTHLDQTG-KLIKYSDFVN

Query:  KELILFSMADNQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDH
        KELILFS +DN+RSIPS+VDG KPGQRK+LF  FKRN  +E KV+Q +G V+E SAYHHGEQ+L  TI+ +AQ++VGSNNINLL P GQFGTR HGGKD 
Subjt:  KELILFSMADNQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDH

Query:  ASSRYIYTKLSNVTRFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIE
        AS RYI+T LS++ R LFP  DD LL +L +D Q +EP WY+PIIP VL+NG EGIGTGW+  +PNY+ R+I+ NVRRML+G    PM P Y+ F GTI+
Subjt:  ASSRYIYTKLSNVTRFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIE

Query:  KTATKEGGSSYTVSGIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKL
        +     G + Y VSG I  V   T+ ITELPVR WT  YKE    V     N  DK  A     I     +  D +V   V +TEE +  A   GL K  
Subjt:  KTATKEGGSSYTVSGIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKL

Query:  KLTTTISTSNMHLFDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKT
        KL TT++ ++M LFD  G +KKY+  + IL+EFF LRL YY  RK+ L+  L  E  KL N+ RFIL  + G+I + NR + DL   L  +G+   P K 
Subjt:  KLTTTISTSNMHLFDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKT

Query:  -KSVEPEIAGASSETDETEESPEVKGERVS-DYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQ
         K  + + A      ++ ++S    G     D+ Y+L +++ +LT EKV+EL   RD    EV  L++ +P  LW +DL +  +ELD+++  + +
Subjt:  -KSVEPEIAGASSETDETEESPEVKGERVS-DYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQ

Arabidopsis top hits

e value

%identity

Alignment

AT3G10270.1 DNA GYRASE B1

4.4e-23

24.34

Show/hide

Query:  GLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEK--KTTGGRNGYGAKLTNIFSTEF
        GL+ +  EIL NA D  Q       + VV+  + + +S+ +NG G+P ++H        E +   L     +         +GG +G G  + N  S   
Subjt:  GLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEK--KTTGGRNGYGAKLTNIFSTEF

Query:  -VIETADGKRLKKYKQVFSDNMGKKSDPIIT-KC------KEGDNWTKVTFKPDLAKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKS
         VI   DG    +++Q +S     +  P+ T  C        G   T + F PD   F      + + +A   + +  L   +  ++K E +     V S
Subjt:  -VIETADGKRLKKYKQVFSDNMGKKSDPIIT-KC------KEGDNWTKVTFKPDLAKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKS

Query:  FQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVVTLSEGQFQ---------QVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKS
           Y     +  S    +  K  H     R EI  +  +   Q          + + N I TI GGTH++ +   +    +N + KK K   VK + + S
Subjt:  FQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVVTLSEGQFQ---------QVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKS

Query:  YLWV-------------------------------------FINALIDNPAFDSQTKETL---TIR-------QSSFGSACELTPEFLKNVAAKSGIMDS
          W+                                      ++  + NP F+ QTK  L    +R       Q       EL P+ L+++ +KS  +++
Subjt:  YLWV-------------------------------------FINALIDNPAFDSQTKETL---TIR-------QSSFGSACELTPEFLKNVAAKSGIMDS

Query:  VLSWVNFKQSKDLKKTDGT-KTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYI
          + +  K++++L ++    K+  + G  KL D +      SE   + + EGDSA   A  G     R F  + PLRGK+LN+       + +N+EIQ +
Subjt:  VLSWVNFKQSKDLKKTDGT-KTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYI

Query:  KQILGL-QQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNASGWS
           LGL  +G+++N    LRY  ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K   +       Y     +    S  GNAS ++
Subjt:  KQILGL-QQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNASGWS

Query:  IKYYKGLG
        I+ +KGLG
Subjt:  IKYYKGLG

AT3G23890.1 topoisomerase II

0.0e+00

63.55

Show/hide

Query:  KRPLQNSNAANVDQIPAGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNAANV + PA  +     KTIEEMYQKK+QLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R VTYVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNAANVDQIPAGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD
        SV+VVIDVEQN ISV N+G GVPVE+HQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADGKRLKKYKQVF +NMGKKS+
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS-TFTMEPPKRYHVKPNERWEIV
        P+ITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+ + T +P  R   K N+RWE+ 
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS-TFTMEPPKRYHVKPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKN
        V+LSEGQFQQVSFVN IATIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWVF+NALIDNPAFDSQTKETLT+RQSSFGS CEL+ +FLK 
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKN

Query:  VAAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DG KT ++  +EKL+DA  AGG+NS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VAAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE
        T NKEI+ +K+ILGL+Q  +Y +  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT K GT  VLSFY+MPEYE WKE
Subjt:  TENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADN
        SL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKK E RK+WL  + PG HLDQ    + YSDFVNKELILFSMAD 
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADN

Query:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLA  IIGMAQDYVGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSY
         VTR LFPKDDD LL+YL+EDGQ IEPTWYMPIIPTVLVNG EGIGTGWSTFIPNYNPR+I+ NVRR+L+GE+M+PMDPWYRGF GTIEKTA+KEGG +Y
Subjt:  NVTRFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSY

Query:  TVSGIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNM
        T++G+ EEV +TT+RITELP+R+W +DYK FL S+    K D         PF +    ++D+KSV  D+ L+EENM+ A QEG  KK KLTTTI+TSNM
Subjt:  TVSGIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNM

Query:  HLFDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAG--
        HLFD  GVIKKY  PEQILEEFF LR EYYEKRK+ +++N+E+ELLKLENK RFILAV++GEIIV+ RK+ D+  +L+ KGFTPFP+K +SVE  IAG  
Subjt:  HLFDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAG--

Query:  ---ASSETDETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEV--RKQQR
           A+ E +E    PE     +  S+Y+YLLA+AI +LTIEKV+EL  DRDK+   V  ++K TPKSLWL DL+SL+KEL+++D  DAQV +     Q++
Subjt:  ---ASSETDETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEV--RKQQR

Query:  IKANNDVKPKISRNAPKAPRNSKKTSNSETVTESMDTTSSSTTMEVASNA--VVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIE
        I+A +    K+ R APK P   K T  +   +ES  T +S + M+  +N   VVKPK +  A +K  A + +    +  A D D+ V E+         +
Subjt:  IKANNDVKPKISRNAPKAPRNSKKTSNSETVTESMDTTSSSTTMEVASNA--VVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIE

Query:  SSPDRSEVSAMETEVPQAQAAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLIT
             +     E E+        +     APA    TA++ +    DD DD+   + E+ P   KKGG   RK AA  K  KPPAA  K+G +      T
Subjt:  SSPDRSEVSAMETEVPQAQAAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLIT

Query:  QMLEPAENPGISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVLSDSDSEP
        ++L      G+SPEKKVRK+R+SPFNKKS S++ R      + +EEE  E V GN           ++E+S G   A  R QRANR ++ YVLSDS+SE 
Subjt:  QMLEPAENPGISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVLSDSDSEP

Query:  VVEDSDFDEKDADFDED
           DS+FD+ + D D++
Subjt:  VVEDSDFDEKDADFDED

AT3G23890.2 topoisomerase II

0.0e+00

64.07

Show/hide

Query:  KRPLQNSNAANVDQIPAGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNAANV + PA  +     KTIEEMYQKK+QLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R VTYVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNAANVDQIPAGPK-----KTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD
        SV+VVIDVEQN ISV N+G GVPVE+HQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADGKRLKKYKQVF +NMGKKS+
Subjt:  SVKVVIDVEQNCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSD

Query:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS-TFTMEPPKRYHVKPNERWEIV
        P+ITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+ + T +P  R   K N+RWE+ 
Subjt:  PIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSAS-TFTMEPPKRYHVKPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKN
        V+LSEGQFQQVSFVN IATIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWVF+NALIDNPAFDSQTKETLT+RQSSFGS CEL+ +FLK 
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVDYITNQIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKN

Query:  VAAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DG KT ++  +EKL+DA  AGG+NS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VAAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE
        T NKEI+ +K+ILGL+Q  +Y +  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT K GT  VLSFY+MPEYE WKE
Subjt:  TENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADN
        SL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKK E RK+WL  + PG HLDQ    + YSDFVNKELILFSMAD 
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERKDWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADN

Query:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLA  IIGMAQDYVGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSY
         VTR LFPKDDD LL+YL+EDGQ IEPTWYMPIIPTVLVNG EGIGTGWSTFIPNYNPR+I+ NVRR+L+GE+M+PMDPWYRGF GTIEKTA+KEGG +Y
Subjt:  NVTRFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGSSY

Query:  TVSGIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNM
        T++G+ EEV +TT+RITELP+R+W +DYK FL S+    K D         PF +    ++D+KSV  D+ L+EENM+ A QEG  KK KLTTTI+TSNM
Subjt:  TVSGIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTTTISTSNM

Query:  HLFDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAG--
        HLFD  GVIKKY  PEQILEEFF LR EYYEKRK+ +++N+E+ELLKLENK RFILAV++GEIIV+ RK+ D+  +L+ KGFTPFP+K +SVE  IAG  
Subjt:  HLFDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAG--

Query:  ---ASSETDETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEV--RKQQR
           A+ E +E    PE     +  S+Y+YLLA+AI +LTIEKV+EL  DRDK+   V  ++K TPKSLWL DL+SL+KEL+++D  DAQV +     Q++
Subjt:  ---ASSETDETEESPEVKGERV--SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEV--RKQQR

Query:  IKANNDVKPKISRNAPKAPRNSKKTSNSETVTESMDTTSSSTTMEVASNA--VVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIE
        I+A +    K+ R APK P   K T  +   +ES  T +S + M+  +N   VVKPKG+  A +KAPA            E ++DE+L+L  RLA Y   
Subjt:  IKANNDVKPKISRNAPKAPRNSKKTSNSETVTESMDTTSSSTTMEVASNA--VVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIE

Query:  SSPDRSEVSAMETEVPQAQAAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLIT
        S+P              A ++K  E SK              I+ +DD DD    + E+ P   KKGG   RK AA  K  KPPAA  K+G +      T
Subjt:  SSPDRSEVSAMETEVPQAQAAKKKEPSKRAPAKKKTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLIT

Query:  QMLEPAENPGISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVLSDSDSEP
        ++L      G+SPEKKVRK+R+SPFNKKS S++ R      + +EEE  E V GN           ++E+S G   A  R QRANR ++ YVLSDS+SE 
Subjt:  QMLEPAENPGISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEEEEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVLSDSDSEP

Query:  VVEDSDFDEKDADFDED
           DS+FD+ + D D++
Subjt:  VVEDSDFDEKDADFDED

AT5G04130.1 DNA GYRASE B2

2.9e-27

25.08

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Query:  EMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVEVHQE
        E  Q    L+ +  RP  Y+GS                     T   GL+ +  EIL NA D  Q   +   V VV+  +   +SV +NG G+P ++H  
Subjt:  EMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQNCISVFNNGDGVPVEVHQE

Query:  EKVYVPELIFGHLLTSSNYDDAEK--KTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSDPIIT-KCK------EGDNWTKVTFKPD
         K    E +   L     +         +GG +G G  + N  S    +E +  +   ++KQ +S     +  PI T  C+      +G   T + F PD
Subjt:  EKVYVPELIFGHLLTSSNYDDAEK--KTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSDPIIT-KCK------EGDNWTKVTFKPD

Query:  LAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQ-------RVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVVTLSEGQFQ-----
           F  T +E D   +   R+ +LA  L   V + L  +       +    SF   +  Y+   +T         H     R EI     +   Q     
Subjt:  LAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQ-------RVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVVTLSEGQFQ-----

Query:  ----QVSFVNGIATIKGGTHVDYITNQIANYVMNVVNK----KNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETL---TIR-------QSSFGSAC
             + + N I TI GGTH++ +   +   +  +  K    K K+ ++   +V+  L   ++  + NP F+ QTK  L    +R       Q       
Subjt:  ----QVSFVNGIATIKGGTHVDYITNQIANYVMNVVNK----KNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETL---TIR-------QSSFGSAC

Query:  ELTPEFLKNVAAKSGIMDSVLSWVNFKQSKDLKKTDGT-KTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLL
        EL P+ L+++ +KS  +++  + +  K++++L ++    K+  + G  KL D +      SE   + + EGDSA   A  G     R F  + PLRGK+L
Subjt:  ELTPEFLKNVAAKSGIMDSVLSWVNFKQSKDLKKTDGT-KTEKINGIEKLEDANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLL

Query:  NVREASSKQITENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTM
        N+       + +N+EIQ +   LGL    E    + LRY  ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K   +       Y  
Subjt:  NVREASSKQITENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTM

Query:  PEYESWKESLRGNASGWSIKYYKGLG
         + +    +   NAS ++I+ +KGLG
Subjt:  PEYESWKESLRGNASGWSIKYYKGLG

AT5G53960.1 ATP binding;DNA binding;DNA topoisomerase (ATP-hydrolyzing)s

3.5e-04

29.91

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Query:  ENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSETDETEESPEVKGERVSDYEYLLALAIGTLTIEKVQE
        +++E +L+KLENK R+I  V +  I + +  R  L   L+ +GFTPFP                   +E+ P       S Y+YL       L I+K +E
Subjt:  ENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSETDETEESPEVKGERVSDYEYLLALAIGTLTIEKVQE

Query:  LCNDRDKLKGEVEGLRK
        LC+ ++ L+  V  L++
Subjt:  LCNDRDKLKGEVEGLRK

Sequences

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CDS sequence

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ATGGCCGTGGAGAAGAAGCGCCCGCTGCAGAACAGTAACGCCGCCAATGTCGACCAGATTCCGGCAGGGCCGAAGAAGACAATCGAAGAAATGTACCAGAAAAAGACTCA
GCTCGAGCACATTCTCCTCAGGCCCGATACCTACGTTGGATCAATCGAAAAGCACACCCAAAACCTCTGGGTTTACGAGAACGACAAGATGGTGCACCGATCCGTCACCT
ATGTGCCGGGTCTCTACAAGATCTTTGATGAAATTTTGGTCAATGCTGCAGATAACAAACAGAGAGACCCCTCGATGGACTCGGTCAAGGTTGTGATTGATGTTGAACAG
AACTGTATCAGTGTGTTCAACAATGGAGATGGAGTTCCGGTTGAGGTTCATCAGGAAGAGAAGGTTTATGTGCCGGAGTTGATCTTTGGACATCTGTTGACTAGTAGTAA
TTACGATGATGCTGAGAAGAAAACCACTGGTGGAAGAAATGGCTATGGTGCGAAACTTACGAATATTTTTTCGACTGAATTTGTGATCGAGACGGCTGATGGAAAACGCC
TGAAGAAGTATAAGCAGGTATTCTCTGACAACATGGGAAAAAAATCTGACCCGATCATAACAAAGTGCAAGGAGGGTGATAATTGGACTAAAGTGACCTTTAAGCCAGAC
TTGGCAAAGTTCAACATGACTCATCTTGAAGATGATGTTGTTGCACTGATGAAGAAGAGGGTGTTGGATTTGGCCGGATGCCTTGGAAAAACGGTTAAGGTTGAGCTAAA
TGGACAAAGGGTCCCTGTGAAATCATTTCAAGATTATGTAGATCTCTACCTTAAATCGGCATCCACATTCACGATGGAACCTCCAAAAAGGTATCATGTTAAGCCTAATG
AGAGATGGGAAATTGTGGTGACCTTAAGTGAGGGGCAGTTTCAGCAGGTCAGCTTTGTGAACGGGATTGCAACTATCAAGGGCGGGACTCATGTTGATTACATCACTAAT
CAAATAGCAAATTATGTGATGAATGTTGTAAATAAGAAGAACAAAAATGCTAACGTGAAGGCTCACAATGTGAAGAGTTATTTGTGGGTTTTTATCAATGCCCTCATTGA
TAATCCTGCCTTCGACTCCCAAACCAAAGAAACTTTGACAATTCGTCAAAGCAGTTTCGGGTCTGCGTGCGAACTTACGCCAGAGTTTTTGAAGAATGTGGCGGCGAAAT
CTGGAATTATGGACAGCGTTCTCTCGTGGGTTAATTTCAAGCAAAGCAAAGACCTGAAGAAAACTGATGGAACAAAAACAGAAAAAATCAATGGTATCGAAAAGTTGGAG
GATGCCAATTGTGCTGGAGGGAGAAACTCGGAAAAATGTACCTTGATTTTGACAGAAGGAGATTCAGCCAAGGCCCTTGCAATGGCTGGGCTCGGTGTAGTAGGACGGGA
TTTCTATGGCGTATTCCCATTGAGAGGTAAATTGCTCAATGTGAGGGAAGCAAGTAGCAAACAGATCACAGAGAATAAAGAAATTCAGTACATCAAGCAAATACTTGGAC
TTCAGCAAGGGAAGGAATACAACAGTTCTAAGGCTTTGAGATATGGACATTTGATGATTATGACTGATCAGGATCATGATGGTTCGCACATTAAAGGACTCTTGATCAAC
TTTATTCATTCTTTTTGGCCTTCTCTCCTCAGAGTGCCATCTTTTTTGGTTGAGTTCATAACGCCTATTGTCAAGGCTACTCACAAGAATGGAACTGTTTTATCATTCTA
TACCATGCCCGAGTATGAGTCTTGGAAAGAGAGCTTGAGGGGCAATGCAAGTGGCTGGTCAATCAAGTACTATAAGGGGTTGGGAACAAGCACATCCAAAGAAGGAAGAG
AGTACTTTGAACAATTAACAAAGCACAAGAAAGATTTTATTTGGCAAGATGACCATGATGGGGAGGCCATTGAACTTGCCTTCAGTAAGAAAAAGACTGAAGAGAGGAAG
GATTGGCTCCGTCAATTTGAGCCTGGTACCCATCTAGATCAGACAGGAAAATTGATAAAATACAGCGACTTTGTCAACAAGGAGCTTATATTATTTTCAATGGCTGATAA
TCAAAGGTCTATTCCCTCGATGGTTGATGGCCTCAAGCCCGGTCAGAGGAAGATCCTATTCTGTTCTTTCAAGAGAAACTTCATCAAAGAAGCCAAAGTTTCTCAATTTT
CCGGTTACGTATCTGAGCATTCTGCTTATCATCATGGCGAGCAGAGTCTTGCTGGCACCATCATTGGAATGGCACAAGATTATGTCGGCAGTAACAACATAAATCTTCTT
TTGCCAAATGGACAATTTGGCACCCGGAACCATGGAGGCAAAGATCATGCAAGTTCTAGGTACATTTACACTAAGCTCTCAAATGTTACAAGGTTCCTTTTCCCAAAAGA
TGATGATAAGCTTCTCAACTACTTAAGTGAAGATGGTCAGTCAATTGAACCAACTTGGTATATGCCTATCATACCGACGGTTCTTGTCAACGGAGGCGAAGGAATAGGAA
CTGGGTGGAGTACGTTCATTCCAAATTATAATCCTAGAGATATCATTAGAAATGTAAGACGCATGTTGGACGGTGAAACAATGTTGCCAATGGATCCATGGTATAGAGGT
TTTTCAGGAACTATAGAGAAAACTGCCACTAAAGAAGGAGGTAGTAGTTACACTGTTAGTGGGATTATAGAGGAAGTCAGTGACACGACATTGAGAATAACTGAACTGCC
AGTTCGCAAATGGACTAATGATTATAAGGAATTCCTTGATTCTGTCACGAGGACATCCAAGAATGATAAAGACAAAGAAAAAGCAGCGAAGGATCCTTTTATTGAGCAAG
CTGATCACCACAGCGATGACAAAAGTGTTTCCATTGATGTTCACTTGACGGAGGAAAACATGATACTGGCCATGCAGGAGGGTTTGAAGAAGAAACTCAAATTAACTACT
ACTATCAGCACAAGCAACATGCATCTTTTTGATGCAAATGGCGTGATTAAGAAATATGATAACCCAGAACAAATTCTTGAAGAGTTTTTCCCCCTTAGACTTGAATACTA
TGAGAAAAGAAAGAAAAATCTTTTGGAGAACCTTGAATTGGAGTTGCTCAAACTGGAGAACAAGGTGAGGTTTATCCTTGCTGTTGTGAATGGAGAGATAATAGTAAGCA
ATAGAAAAAGAGTTGATTTGTTCCATGAGCTTCAAGCGAAAGGCTTTACACCCTTTCCAAAGAAGACTAAATCTGTTGAGCCGGAGATTGCTGGAGCATCTAGTGAAACT
GATGAAACAGAGGAGAGTCCTGAAGTAAAAGGGGAACGGGTTAGTGACTACGAGTATCTATTGGCTTTGGCAATTGGAACCTTGACCATTGAGAAGGTTCAGGAGCTATG
TAATGATAGAGACAAGCTCAAAGGGGAAGTGGAAGGTTTGAGGAAGGCAACACCCAAGTCTTTGTGGCTGAAAGATCTTGATTCTCTTGAGAAGGAACTTGATGAGATGG
ATAGAAATGATGCTCAAGTAGATGAGGTAAGAAAACAGCAGAGAATCAAAGCAAACAACGATGTAAAGCCAAAGATCTCTAGAAATGCACCAAAAGCTCCACGTAACAGC
AAGAAAACCAGCAATTCGGAAACTGTCACGGAAAGTATGGACACAACATCTAGTTCTACAACAATGGAAGTTGCAAGTAACGCGGTGGTGAAGCCCAAAGGCAAAGCAGC
GGCTCCAAGAAAAGCTCCTGCTAAAAAGGGTAAAGCTGCAGTTATCAACGACGATGCTGAAGATGATGACGATGAAGTGCTCGAGCTTAAAGATCGTCTTGCTGCCTACA
AAATTGAATCATCTCCTGATCGTTCGGAAGTTTCAGCCATGGAAACTGAAGTGCCACAAGCACAGGCGGCCAAGAAGAAAGAACCAAGCAAGAGAGCCCCTGCCAAAAAG
AAAACAACTGCCAAGTCTGGTCAGATTTCCGACAATGACGACACCGACGACGAGGACTTCGAAATAAAGGAGATAGGTCCTCCAGCAGCCAAGAAGGGAGGAGGAGGGAG
AAGAAAGGCAGCTGCAAATGCCAAAACAACCAAACCCCCTGCAGCAGCAGCGAAGAAGGGGGCGAAGTTGGGGCAGAAACTAATAACTCAAATGCTGGAACCGGCGGAGA
ACCCCGGCATCTCGCCGGAGAAGAAGGTGAGAAAGATCAGAGCATCACCTTTCAACAAGAAAAGTGGCTCTATCTTGGGAAGAGCTGGGATAGAAGAAGAAGAAGAAGAA
GAAGAAGAAGAAGAAGAAGAGGTAGGTGGAAATGAAGGGAAGATAATGGGCTCTGGTTCTTCTGAGACGACTGAAGAATCCGCCGGATTTCCGCCGGCGAGAGGAAGATC
ACAGAGAGCGAACAGAACTCAGGTGAGATATGTGCTTAGTGATTCAGACAGTGAACCAGTTGTTGAGGATTCGGACTTTGATGAAAAAGATGCTGACTTTGATGAAGATT
GA

mRNA sequence

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CACCATCTCTGTGTCTTCTCTCTCTCTTCCACTCTCTCTCAAGAAAGCTTATTCCGATCACCATGGCCGTGGAGAAGAAGCGCCCGCTGCAGAACAGTAACGCCGCCAAT
GTCGACCAGATTCCGGCAGGGCCGAAGAAGACAATCGAAGAAATGTACCAGAAAAAGACTCAGCTCGAGCACATTCTCCTCAGGCCCGATACCTACGTTGGATCAATCGA
AAAGCACACCCAAAACCTCTGGGTTTACGAGAACGACAAGATGGTGCACCGATCCGTCACCTATGTGCCGGGTCTCTACAAGATCTTTGATGAAATTTTGGTCAATGCTG
CAGATAACAAACAGAGAGACCCCTCGATGGACTCGGTCAAGGTTGTGATTGATGTTGAACAGAACTGTATCAGTGTGTTCAACAATGGAGATGGAGTTCCGGTTGAGGTT
CATCAGGAAGAGAAGGTTTATGTGCCGGAGTTGATCTTTGGACATCTGTTGACTAGTAGTAATTACGATGATGCTGAGAAGAAAACCACTGGTGGAAGAAATGGCTATGG
TGCGAAACTTACGAATATTTTTTCGACTGAATTTGTGATCGAGACGGCTGATGGAAAACGCCTGAAGAAGTATAAGCAGGTATTCTCTGACAACATGGGAAAAAAATCTG
ACCCGATCATAACAAAGTGCAAGGAGGGTGATAATTGGACTAAAGTGACCTTTAAGCCAGACTTGGCAAAGTTCAACATGACTCATCTTGAAGATGATGTTGTTGCACTG
ATGAAGAAGAGGGTGTTGGATTTGGCCGGATGCCTTGGAAAAACGGTTAAGGTTGAGCTAAATGGACAAAGGGTCCCTGTGAAATCATTTCAAGATTATGTAGATCTCTA
CCTTAAATCGGCATCCACATTCACGATGGAACCTCCAAAAAGGTATCATGTTAAGCCTAATGAGAGATGGGAAATTGTGGTGACCTTAAGTGAGGGGCAGTTTCAGCAGG
TCAGCTTTGTGAACGGGATTGCAACTATCAAGGGCGGGACTCATGTTGATTACATCACTAATCAAATAGCAAATTATGTGATGAATGTTGTAAATAAGAAGAACAAAAAT
GCTAACGTGAAGGCTCACAATGTGAAGAGTTATTTGTGGGTTTTTATCAATGCCCTCATTGATAATCCTGCCTTCGACTCCCAAACCAAAGAAACTTTGACAATTCGTCA
AAGCAGTTTCGGGTCTGCGTGCGAACTTACGCCAGAGTTTTTGAAGAATGTGGCGGCGAAATCTGGAATTATGGACAGCGTTCTCTCGTGGGTTAATTTCAAGCAAAGCA
AAGACCTGAAGAAAACTGATGGAACAAAAACAGAAAAAATCAATGGTATCGAAAAGTTGGAGGATGCCAATTGTGCTGGAGGGAGAAACTCGGAAAAATGTACCTTGATT
TTGACAGAAGGAGATTCAGCCAAGGCCCTTGCAATGGCTGGGCTCGGTGTAGTAGGACGGGATTTCTATGGCGTATTCCCATTGAGAGGTAAATTGCTCAATGTGAGGGA
AGCAAGTAGCAAACAGATCACAGAGAATAAAGAAATTCAGTACATCAAGCAAATACTTGGACTTCAGCAAGGGAAGGAATACAACAGTTCTAAGGCTTTGAGATATGGAC
ATTTGATGATTATGACTGATCAGGATCATGATGGTTCGCACATTAAAGGACTCTTGATCAACTTTATTCATTCTTTTTGGCCTTCTCTCCTCAGAGTGCCATCTTTTTTG
GTTGAGTTCATAACGCCTATTGTCAAGGCTACTCACAAGAATGGAACTGTTTTATCATTCTATACCATGCCCGAGTATGAGTCTTGGAAAGAGAGCTTGAGGGGCAATGC
AAGTGGCTGGTCAATCAAGTACTATAAGGGGTTGGGAACAAGCACATCCAAAGAAGGAAGAGAGTACTTTGAACAATTAACAAAGCACAAGAAAGATTTTATTTGGCAAG
ATGACCATGATGGGGAGGCCATTGAACTTGCCTTCAGTAAGAAAAAGACTGAAGAGAGGAAGGATTGGCTCCGTCAATTTGAGCCTGGTACCCATCTAGATCAGACAGGA
AAATTGATAAAATACAGCGACTTTGTCAACAAGGAGCTTATATTATTTTCAATGGCTGATAATCAAAGGTCTATTCCCTCGATGGTTGATGGCCTCAAGCCCGGTCAGAG
GAAGATCCTATTCTGTTCTTTCAAGAGAAACTTCATCAAAGAAGCCAAAGTTTCTCAATTTTCCGGTTACGTATCTGAGCATTCTGCTTATCATCATGGCGAGCAGAGTC
TTGCTGGCACCATCATTGGAATGGCACAAGATTATGTCGGCAGTAACAACATAAATCTTCTTTTGCCAAATGGACAATTTGGCACCCGGAACCATGGAGGCAAAGATCAT
GCAAGTTCTAGGTACATTTACACTAAGCTCTCAAATGTTACAAGGTTCCTTTTCCCAAAAGATGATGATAAGCTTCTCAACTACTTAAGTGAAGATGGTCAGTCAATTGA
ACCAACTTGGTATATGCCTATCATACCGACGGTTCTTGTCAACGGAGGCGAAGGAATAGGAACTGGGTGGAGTACGTTCATTCCAAATTATAATCCTAGAGATATCATTA
GAAATGTAAGACGCATGTTGGACGGTGAAACAATGTTGCCAATGGATCCATGGTATAGAGGTTTTTCAGGAACTATAGAGAAAACTGCCACTAAAGAAGGAGGTAGTAGT
TACACTGTTAGTGGGATTATAGAGGAAGTCAGTGACACGACATTGAGAATAACTGAACTGCCAGTTCGCAAATGGACTAATGATTATAAGGAATTCCTTGATTCTGTCAC
GAGGACATCCAAGAATGATAAAGACAAAGAAAAAGCAGCGAAGGATCCTTTTATTGAGCAAGCTGATCACCACAGCGATGACAAAAGTGTTTCCATTGATGTTCACTTGA
CGGAGGAAAACATGATACTGGCCATGCAGGAGGGTTTGAAGAAGAAACTCAAATTAACTACTACTATCAGCACAAGCAACATGCATCTTTTTGATGCAAATGGCGTGATT
AAGAAATATGATAACCCAGAACAAATTCTTGAAGAGTTTTTCCCCCTTAGACTTGAATACTATGAGAAAAGAAAGAAAAATCTTTTGGAGAACCTTGAATTGGAGTTGCT
CAAACTGGAGAACAAGGTGAGGTTTATCCTTGCTGTTGTGAATGGAGAGATAATAGTAAGCAATAGAAAAAGAGTTGATTTGTTCCATGAGCTTCAAGCGAAAGGCTTTA
CACCCTTTCCAAAGAAGACTAAATCTGTTGAGCCGGAGATTGCTGGAGCATCTAGTGAAACTGATGAAACAGAGGAGAGTCCTGAAGTAAAAGGGGAACGGGTTAGTGAC
TACGAGTATCTATTGGCTTTGGCAATTGGAACCTTGACCATTGAGAAGGTTCAGGAGCTATGTAATGATAGAGACAAGCTCAAAGGGGAAGTGGAAGGTTTGAGGAAGGC
AACACCCAAGTCTTTGTGGCTGAAAGATCTTGATTCTCTTGAGAAGGAACTTGATGAGATGGATAGAAATGATGCTCAAGTAGATGAGGTAAGAAAACAGCAGAGAATCA
AAGCAAACAACGATGTAAAGCCAAAGATCTCTAGAAATGCACCAAAAGCTCCACGTAACAGCAAGAAAACCAGCAATTCGGAAACTGTCACGGAAAGTATGGACACAACA
TCTAGTTCTACAACAATGGAAGTTGCAAGTAACGCGGTGGTGAAGCCCAAAGGCAAAGCAGCGGCTCCAAGAAAAGCTCCTGCTAAAAAGGGTAAAGCTGCAGTTATCAA
CGACGATGCTGAAGATGATGACGATGAAGTGCTCGAGCTTAAAGATCGTCTTGCTGCCTACAAAATTGAATCATCTCCTGATCGTTCGGAAGTTTCAGCCATGGAAACTG
AAGTGCCACAAGCACAGGCGGCCAAGAAGAAAGAACCAAGCAAGAGAGCCCCTGCCAAAAAGAAAACAACTGCCAAGTCTGGTCAGATTTCCGACAATGACGACACCGAC
GACGAGGACTTCGAAATAAAGGAGATAGGTCCTCCAGCAGCCAAGAAGGGAGGAGGAGGGAGAAGAAAGGCAGCTGCAAATGCCAAAACAACCAAACCCCCTGCAGCAGC
AGCGAAGAAGGGGGCGAAGTTGGGGCAGAAACTAATAACTCAAATGCTGGAACCGGCGGAGAACCCCGGCATCTCGCCGGAGAAGAAGGTGAGAAAGATCAGAGCATCAC
CTTTCAACAAGAAAAGTGGCTCTATCTTGGGAAGAGCTGGGATAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAGGTAGGTGGAAATGAAGGGAAGATAATG
GGCTCTGGTTCTTCTGAGACGACTGAAGAATCCGCCGGATTTCCGCCGGCGAGAGGAAGATCACAGAGAGCGAACAGAACTCAGGTGAGATATGTGCTTAGTGATTCAGA
CAGTGAACCAGTTGTTGAGGATTCGGACTTTGATGAAAAAGATGCTGACTTTGATGAAGATTGAAGAAGCATTTGATCTTCATGGCTTTGTTTGGTCTGTCTTCCGAGTG
TATTATTTTAAGCAGTAAAATTTAGGAAGCAAAGCAATACGATGCTCAGTGTTGAATGGAATATCCAACTGAAGTAAATAAAAAAGAAAACTTCATTACAAAAGC

Protein sequence

Show/hide protein sequence

MAVEKKRPLQNSNAANVDQIPAGPKKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSVTYVPGLYKIFDEILVNAADNKQRDPSMDSVKVVIDVEQ
NCISVFNNGDGVPVEVHQEEKVYVPELIFGHLLTSSNYDDAEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRLKKYKQVFSDNMGKKSDPIITKCKEGDNWTKVTFKPD
LAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASTFTMEPPKRYHVKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVDYITN
QIANYVMNVVNKKNKNANVKAHNVKSYLWVFINALIDNPAFDSQTKETLTIRQSSFGSACELTPEFLKNVAAKSGIMDSVLSWVNFKQSKDLKKTDGTKTEKINGIEKLE
DANCAGGRNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNSSKALRYGHLMIMTDQDHDGSHIKGLLIN
FIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDHDGEAIELAFSKKKTEERK
DWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADNQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLL
LPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLSEDGQSIEPTWYMPIIPTVLVNGGEGIGTGWSTFIPNYNPRDIIRNVRRMLDGETMLPMDPWYRG
FSGTIEKTATKEGGSSYTVSGIIEEVSDTTLRITELPVRKWTNDYKEFLDSVTRTSKNDKDKEKAAKDPFIEQADHHSDDKSVSIDVHLTEENMILAMQEGLKKKLKLTT
TISTSNMHLFDANGVIKKYDNPEQILEEFFPLRLEYYEKRKKNLLENLELELLKLENKVRFILAVVNGEIIVSNRKRVDLFHELQAKGFTPFPKKTKSVEPEIAGASSET
DETEESPEVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVEGLRKATPKSLWLKDLDSLEKELDEMDRNDAQVDEVRKQQRIKANNDVKPKISRNAPKAPRNS
KKTSNSETVTESMDTTSSSTTMEVASNAVVKPKGKAAAPRKAPAKKGKAAVINDDAEDDDDEVLELKDRLAAYKIESSPDRSEVSAMETEVPQAQAAKKKEPSKRAPAKK
KTTAKSGQISDNDDTDDEDFEIKEIGPPAAKKGGGGRRKAAANAKTTKPPAAAAKKGAKLGQKLITQMLEPAENPGISPEKKVRKIRASPFNKKSGSILGRAGIEEEEEE
EEEEEEEVGGNEGKIMGSGSSETTEESAGFPPARGRSQRANRTQVRYVLSDSDSEPVVEDSDFDEKDADFDED

Tan0005552 (gene) of Snake gourd v1 genome