CuGenDBv2

Gene ID	Tan0010277
Organism	Trichosanthes anguina (Snake gourd v1)
Description	Cytochrome f
Genome location	LG01:107318209..107319501
RNA-Seq Expression	Tan0010277
Synteny	Tan0010277
Gene Ontology terms	GO:0015979 - photosynthesis (biological process) GO:0022900 - electron transport chain (biological process) GO:0009535 - chloroplast thylakoid membrane (cellular component) GO:0031361 - integral component of thylakoid membrane (cellular component) GO:0005506 - iron ion binding (molecular function) GO:0009055 - electron transfer activity (molecular function) GO:0020037 - heme binding (molecular function)
InterPro domains	IPR002325 - Cytochrome f IPR011054 - Rudiment single hybrid motif IPR024058 - Cytochrome f transmembrane anchor IPR024094 - Cytochrome f large domain IPR036826 - Cytochrome f large domain superfamily

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

YP_004841796.1 cytochrome f [Cucumis melo subsp. melo]

1.7e-80

82.41

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Query:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------
        DRISPE KE MGNLSFQSYRPTKKNILVIG VPGQKYSEI FPILSPDPATKKDVHFLKYPIYVGGNR RGQIYPDGSKSNNNVYNAT            
Subjt:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------

Query:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
          GYE+TI+DAANGRQVVDIIPPGPELLVS+ +SIKLDQPLTSNPNVGGF          D LRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
Subjt:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF

YP_009317399.1 cytochrome f [Coccinia grandis]

4.9e-80

81.91

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Query:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------
        DRISPE KE MGNLSFQSYRPTKKNILVIG VPGQKYSEI FPILSPDPATKKDVHFLKYPIYVGGNR RGQIYPDGSKSNNNVYNAT            
Subjt:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------

Query:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
          GYE+TI+D ANGRQVVDIIPPGPELLVS+ +SIKLDQPLTSNPNVGGF          D LRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
Subjt:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF

YP_009326002.1 cytochrome f [Citrullus lanatus]

1.7e-80

82.41

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Query:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------
        DRISPE KE MGNLSFQSYRPTKKNILVIG VPGQKYSEI FPILSPDPATKKDVHFLKYPIYVGGNR RGQIYPDGSKSNNNVYNAT            
Subjt:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------

Query:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
          GYE+TI+DAANGRQVVDIIPPGPELLVS+ +SIKLDQPLTSNPNVGGF          D LRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
Subjt:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF

YP_009752003.1 cytochrome f [Cionosicys macranthus]

1.7e-80

82.41

Show/hide

Query:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------
        DRISPE KE MGNLSFQSYRPTKKNILVIG VPGQKYSEI FPILSPDPATKKDVHFLKYPIYVGGNR RGQIYPDGSKSNNNVYNAT            
Subjt:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------

Query:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
          GYE+TI+DAANGRQVVDIIPPGPELLVS+ +SIKLDQPLTSNPNVGGF          D LRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
Subjt:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF

YP_010131107.1 cytochrome f [Benincasa hispida]

1.7e-80

82.41

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Query:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------
        DRISPE KE MGNLSFQSYRPTKKNILVIG VPGQKYSEI FPILSPDPATKKDVHFLKYPIYVGGNR RGQIYPDGSKSNNNVYNAT            
Subjt:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------

Query:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
          GYE+TI+DAANGRQVVDIIPPGPELLVS+ +SIKLDQPLTSNPNVGGF          D LRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
Subjt:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF

TrEMBL top hits

e value

%identity

Alignment

A0A1P8LE85 Cytochrome f

8.1e-81

82.41

Show/hide

Query:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------
        DRISPE KE MGNLSFQSYRPTKKNILVIG VPGQKYSEI FPILSPDPATKKDVHFLKYPIYVGGNR RGQIYPDGSKSNNNVYNAT            
Subjt:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------

Query:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
          GYE+TI+DAANGRQVVDIIPPGPELLVS+ +SIKLDQPLTSNPNVGGF          D LRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
Subjt:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF

A0A1S4EU17 Cytochrome f

8.1e-81

82.41

Show/hide

Query:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------
        DRISPE KE MGNLSFQSYRPTKKNILVIG VPGQKYSEI FPILSPDPATKKDVHFLKYPIYVGGNR RGQIYPDGSKSNNNVYNAT            
Subjt:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------

Query:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
          GYE+TI+DAANGRQVVDIIPPGPELLVS+ +SIKLDQPLTSNPNVGGF          D LRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
Subjt:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF

A0A1X9Q151 Cytochrome f

8.1e-81

82.41

Show/hide

Query:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------
        DRISPE KE MGNLSFQSYRPTKKNILVIG VPGQKYSEI FPILSPDPATKKDVHFLKYPIYVGGNR RGQIYPDGSKSNNNVYNAT            
Subjt:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------

Query:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
          GYE+TI+DAANGRQVVDIIPPGPELLVS+ +SIKLDQPLTSNPNVGGF          D LRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
Subjt:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF

A0A218KG41 Cytochrome f

8.1e-81

82.41

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Query:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------
        DRISPE KE MGNLSFQSYRPTKKNILVIG VPGQKYSEI FPILSPDPATKKDVHFLKYPIYVGGNR RGQIYPDGSKSNNNVYNAT            
Subjt:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------

Query:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
          GYE+TI+DAANGRQVVDIIPPGPELLVS+ +SIKLDQPLTSNPNVGGF          D LRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
Subjt:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF

A0A249RZB7 Cytochrome f

8.1e-81

82.41

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Query:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------
        DRISPE KE MGNLSFQSYRPTKKNILVIG VPGQKYSEI FPILSPDPATKKDVHFLKYPIYVGGNR RGQIYPDGSKSNNNVYNAT            
Subjt:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------

Query:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
          GYE+TI+DAANGRQVVDIIPPGPELLVS+ +SIKLDQPLTSNPNVGGF          D LRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
Subjt:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF

SwissProt top hits

e value

%identity

Alignment

A6MM49 Cytochrome f

5.1e-80

79.4

Show/hide

Query:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------
        DRISPE KE +GNLSFQSYRPTKKNILVIG VPGQKYSEI FPILSPDPATKKDVHFLKYPIYVGGNR RGQIYPDGSKSNN VYNAT            
Subjt:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------

Query:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
          GYE+TI DA++G QVV+IIPPGPELLVS+ +SIKLDQPLTSNPNVGGF          D LRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
Subjt:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF

B1NWG3 Cytochrome f

3.9e-80

79.4

Show/hide

Query:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------
        DRISPE KE MGNLSFQSYRPTKKNILVIG VPGQKYSEI FPILSPDPA KKDVHFLKYPIYVGGNR RGQIYPDGSKSNN VYNAT            
Subjt:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------

Query:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
          GYE+TI DA+ GRQV+DIIPPGPELLVS+ +SIKLDQPLTSNPNVGGF          D LRVQGLLFF ASVILAQIFLVLKKKQFEKVQLSEMNF
Subjt:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF

Q1KXU6 Cytochrome f

6.6e-80

78.89

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Query:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------
        DRISPE KE MGNLSFQSYRP +KNILVIG VPGQKYSEI FPILSPDPATKKD+HFLKYPIYVGGNR RGQIYPDGSKSNN VYNAT            
Subjt:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------

Query:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
          GYE+TI DA++GRQVVDIIPPGPELLVS+ +SIKLDQPLTSNPNVGGF          D LRVQGLLFFFA+VILAQIFLVLKKKQFEKVQLSEMNF
Subjt:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF

Q2QD76 Cytochrome f

2.2e-83

82.41

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Query:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------
        DRISPE KE MGNLSFQSYRPTKKNILVIG VPGQKYSEI FPILSPDPATKKDVHFLKYPIYVGGNR RGQIYPDGSKSNNNVYNAT            
Subjt:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------

Query:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
          GYE+TI+DAANGRQVVDIIPPGPELLVS+ +SIKLDQPLTSNPNVGGF          D LRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
Subjt:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF

Q68RZ3 Cytochrome f

5.1e-80

79.4

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Query:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------
        DRISPE KE +GNLSFQSYRPTKKNILVIG VPGQKYSEI FPILSPDPATKKDVHFLKYPIYVGGNR RGQIYPDGSKSNN VYNAT            
Subjt:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVI----------

Query:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
          GYE+TI DA++GRQVVDIIPPGPELLVS+ +SIK DQPLTSNPNVGGF          D LRVQGLLFF ASVILAQIFLVLKKKQFEKVQLSEMNF
Subjt:  --GYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF

Arabidopsis top hits

e value

%identity

Alignment

ATCG00540.1 photosynthetic electron transfer A

5.4e-77

75.38

Show/hide

Query:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATV-----------
        DRISPE KE +GNLSFQ+YRP KKNILVIG VPGQKYSEI FPIL+PDPAT KDVHFLKYPIYVGGNR RGQIYPDGSKSNN VYNAT            
Subjt:  DRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATV-----------

Query:  -IGYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF
          GYE+TI+DA+NGR+V+DIIP G ELLVS+ +SIKLDQPLTSNPNVGGF          D LRVQGLLFF  SV+LAQIFLVLKKKQFEKVQLSEMNF
Subjt:  -IGYELTIMDAANGRQVVDIIPPGPELLVSKEKSIKLDQPLTSNPNVGGF----------DLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGGACCTTTCTGATCGTATTTCTCCTGAGAGTAAAGAAAATATGGGCAATCTGTCTTTTCAGAGCTATCGCCCCACTAAAAAAAATATTCTTGTGATAGGACATGTTCC
TGGTCAGAAATATAGTGAAATCATTTTTCCTATTCTTTCCCCGGACCCTGCGACTAAGAAAGATGTTCACTTCTTAAAATATCCCATATACGTAGGCGGGAACAGGAGAA
GGGGTCAGATTTATCCCGACGGGAGTAAAAGTAATAATAATGTTTATAATGCTACAGTAATAGGATATGAATTAACCATAATGGATGCAGCGAATGGGCGTCAAGTGGTT
GATATTATCCCTCCAGGACCAGAACTTCTTGTTTCAAAGGAAAAATCTATCAAACTTGATCAACCATTAACGAGTAATCCTAATGTGGGAGGGTTTGATCTATTACGTGT
CCAAGGTCTTTTGTTCTTTTTTGCCTCTGTTATTTTGGCACAAATCTTTTTAGTTCTTAAAAAGAAACAGTTTGAGAAGGTTCAATTGTCTGAAATGAATTTCTAA

mRNA sequence

Show/hide mRNA sequence

Protein sequence

Show/hide protein sequence

MDLSDRISPESKENMGNLSFQSYRPTKKNILVIGHVPGQKYSEIIFPILSPDPATKKDVHFLKYPIYVGGNRRRGQIYPDGSKSNNNVYNATVIGYELTIMDAANGRQVV
DIIPPGPELLVSKEKSIKLDQPLTSNPNVGGFDLLRVQGLLFFFASVILAQIFLVLKKKQFEKVQLSEMNF

Tan0010277 (gene) of Snake gourd v1 genome