CuGenDBv2

Gene ID	Tan0012612
Organism	Trichosanthes anguina (Snake gourd v1)
Description	haloacid dehalogenase-like hydrolase domain-containing protein 3
Genome location	LG01:65420011..65421942
RNA-Seq Expression	Tan0012612
Synteny	Tan0012612
Gene Ontology terms	GO:0016021 - integral component of membrane (cellular component) GO:0003676 - nucleic acid binding (molecular function) GO:0016787 - hydrolase activity (molecular function)
InterPro domains	IPR006439 - HAD hydrolase, subfamily IA IPR023214 - HAD superfamily IPR036412 - HAD-like superfamily IPR041492 - Haloacid dehalogenase-like hydrolase

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAG6585872.1 Haloacid dehalogenase-like hydrolase domain-containing protein 3, partial [Cucurbita argyrosperma subsp. sororia]

7.0e-60

93.55

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Query:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA
        YYANGDAWHLP GAYA LTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALD+LGV +NKAVHVGDDQKADKEGAN 
Subjt:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA

Query:  VGIACWLWGTDVTTFQDVQNRILV
        VGIACWLWG DVTTFQD+QNRILV
Subjt:  VGIACWLWGTDVTTFQDVQNRILV

XP_022951708.1 haloacid dehalogenase-like hydrolase domain-containing protein 3 isoform X1 [Cucurbita moschata]

7.0e-60

93.55

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Query:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA
        YYANGDAWHLP GAYA LTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALD+LGV +NKAVHVGDDQKADKEGAN 
Subjt:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA

Query:  VGIACWLWGTDVTTFQDVQNRILV
        VGIACWLWG DVTTFQDVQNRIL+
Subjt:  VGIACWLWGTDVTTFQDVQNRILV

XP_022973291.1 haloacid dehalogenase-like hydrolase domain-containing protein 3 isoform X1 [Cucurbita maxima]

7.0e-60

93.55

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Query:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA
        YYANGDAWHLP GAYA LTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALD+LGV +NKAVHVGDDQKADKEGAN 
Subjt:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA

Query:  VGIACWLWGTDVTTFQDVQNRILV
        VGIACWLWG DVTTFQDVQNRIL+
Subjt:  VGIACWLWGTDVTTFQDVQNRILV

XP_023538135.1 haloacid dehalogenase-like hydrolase domain-containing protein 3 [Cucurbita pepo subsp. pepo]

7.0e-60

93.55

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Query:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA
        YYANGDAWHLP GAYA LTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALD+LGV +NKAVHVGDDQKADKEGAN 
Subjt:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA

Query:  VGIACWLWGTDVTTFQDVQNRILV
        VGIACWLWG DVTTFQDVQNRIL+
Subjt:  VGIACWLWGTDVTTFQDVQNRILV

XP_038891067.1 haloacid dehalogenase-like hydrolase domain-containing protein 3 [Benincasa hispida]

5.0e-58

91.13

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Query:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA
        YYANGDAWHLP GA ATL VLKDAGV++AVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDG+IFEAALDQLGVTS+KAVHVGDDQKADKEGANA
Subjt:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA

Query:  VGIACWLWGTDVTTFQDVQNRILV
        VGIACWLWG+DVTTF+DVQN+IL+
Subjt:  VGIACWLWGTDVTTFQDVQNRILV

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LN41 Uncharacterized protein

7.8e-57

87.2

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Query:  FYYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGAN
        FYYANG+AWHLP GAYATL VLKDAGV++AVVSNFDTRLRKLLKDL+VLDMFDAVIISAEVGYEKPDG+IFEAALDQLGV S+KAVHVGDDQKADKEGAN
Subjt:  FYYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGAN

Query:  AVGIACWLWGTDVTTFQDVQNRILV
        AVGI CWLWG+DV TF+D++N+ILV
Subjt:  AVGIACWLWGTDVTTFQDVQNRILV

A0A5A7SP05 Haloacid dehalogenase-like hydrolase domain-containing protein 3

1.3e-56

85.27

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Query:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA
        YYANG+AWHLP GAYATL VLKDAGV++AVVSNFDTRLRKLLKDL+VLDMFDAVIISAEVGYEKPDG+IFEAALDQL V S+ AVHVGDDQKADKEGANA
Subjt:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA

Query:  VGIACWLWGTDVTTFQDVQNRILVRDSSF
        VGI CWLWG+DV TF+D+QN+ILVR S F
Subjt:  VGIACWLWGTDVTTFQDVQNRILVRDSSF

A0A5D3BJY0 Haloacid dehalogenase-like hydrolase domain-containing protein 3

1.3e-56

85.27

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Query:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA
        YYANG+AWHLP GAYATL VLKDAGV++AVVSNFDTRLRKLLKDL+VLDMFDAVIISAEVGYEKPDG+IFEAALDQL V S+ AVHVGDDQKADKEGANA
Subjt:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA

Query:  VGIACWLWGTDVTTFQDVQNRILVRDSSF
        VGI CWLWG+DV TF+D+QN+ILVR S F
Subjt:  VGIACWLWGTDVTTFQDVQNRILVRDSSF

A0A6J1GIH5 haloacid dehalogenase-like hydrolase domain-containing protein 3 isoform X1

3.4e-60

93.55

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Query:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA
        YYANGDAWHLP GAYA LTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALD+LGV +NKAVHVGDDQKADKEGAN 
Subjt:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA

Query:  VGIACWLWGTDVTTFQDVQNRILV
        VGIACWLWG DVTTFQDVQNRIL+
Subjt:  VGIACWLWGTDVTTFQDVQNRILV

A0A6J1I751 haloacid dehalogenase-like hydrolase domain-containing protein 3 isoform X1

3.4e-60

93.55

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Query:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA
        YYANGDAWHLP GAYA LTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALD+LGV +NKAVHVGDDQKADKEGAN 
Subjt:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA

Query:  VGIACWLWGTDVTTFQDVQNRILV
        VGIACWLWG DVTTFQDVQNRIL+
Subjt:  VGIACWLWGTDVTTFQDVQNRILV

SwissProt top hits

e value

%identity

Alignment

Q5E9D6 Haloacid dehalogenase-like hydrolase domain-containing protein 3

3.6e-14

38.68

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Query:  YANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANAV
        +++   W +  GA ATL   +  G+K+AVVSNFD RL  +L+ + + + FD V+ S   G+ KPD +IF  AL    V      H+GD  + D +GA AV
Subjt:  YANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANAV

Query:  GIACWL
        G+  +L
Subjt:  GIACWL

Q5HZL9 Haloacid dehalogenase-like hydrolase domain-containing protein 3

1.8e-10

36.79

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Query:  YANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANAV
        ++    W L  GA   L    + G+++AV+SNFD RL +LL+   +   FD V+ +   G  KP   IF  AL    V  ++AVHVGDD   D   A  V
Subjt:  YANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANAV

Query:  GIACWL
        G+  +L
Subjt:  GIACWL

Q7T012 Haloacid dehalogenase-like hydrolase domain-containing protein 3

9.1e-10

33.02

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Query:  YANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANAV
        +   + W +   + +TL      G+K  VVSNFD RL  +L+   +L  F  ++ S +    KPD  IF  AL++ GV ++  VHVGD    D   + ++
Subjt:  YANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANAV

Query:  GIACWL
        GI  +L
Subjt:  GIACWL

Q9BSH5 Haloacid dehalogenase-like hydrolase domain-containing protein 3

3.3e-12

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Query:  WHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANAVGIACWL
        W +  GA  TL   +  G+++AV+SNFD RL  +L  L + + FD V+ S   G+ KPD +IF+ AL    +    A HVGD+   D +G  AVG+  +L
Subjt:  WHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANAVGIACWL

Q9CYW4 Haloacid dehalogenase-like hydrolase domain-containing protein 3

7.9e-14

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Query:  WHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANAVGIACWL
        W +  GA  TL   +  G+K+AVVSNFD RL  +L  L + + FD V+ S  VG  KPD +IF  AL +  V    A HVGD    D +G+ AVG+  +L
Subjt:  WHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANAVGIACWL

Arabidopsis top hits

e value

%identity

Alignment

AT1G14310.1 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein

1.6e-54

76.19

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Query:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA
        YYANG+AWHLP GAY T+++LKDAGVK+AVVSNFDTRLRKLLKDLNV+DMFDAVI+SAEVGYEKPD +IF++AL+Q+ V  N+AVHVGDD+ ADK GANA
Subjt:  YYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANA

Query:  VGIACWLWGTDVTTFQDVQNRILVRD
        +GIACWLWG DV TF D+Q RILV +
Subjt:  VGIACWLWGTDVTTFQDVQNRILVRD

AT2G41250.1 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein

1.9e-26

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Query:  YYANGDAWHL-PHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGAN
        Y+    AW L    A      +K+AGVKVA+VSNFDTRLR LL+ L   D FDAV +SAEV  EKP+  IF  A + L V    AVHVGDD++ D  GA 
Subjt:  YYANGDAWHL-PHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGAN

Query:  AVGIACWLWGTDVTTFQDVQNRILVR
          G   WLWG++VT+F+ V  RI V+
Subjt:  AVGIACWLWGTDVTTFQDVQNRILVR

Sequences

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CDS sequence

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ATGAAAAGTTTCTACTATGCGAATGGTGATGCATGGCATCTTCCACATGGAGCTTATGCAACCCTGACCGTTTTGAAAGATGCTGGAGTTAAGGTGGCTGTTGTGTCCAA
CTTTGACACTCGCTTAAGGAAGCTGTTGAAGGATCTAAATGTTTTAGATATGTTTGATGCTGTCATAATATCGGCAGAAGTTGGTTATGAAAAACCAGATGGACAAATAT
TTGAAGCTGCATTAGATCAACTTGGAGTCACATCGAACAAAGCAGTACATGTCGGAGATGATCAGAAGGCAGATAAGGAGGGAGCAAATGCTGTTGGAATAGCTTGCTGG
CTATGGGGAACTGATGTGACGACCTTCCAGGATGTTCAAAACCGAATCCTCGTCCGAGATTCGAGCTTCTAA

mRNA sequence

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Protein sequence

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MKSFYYANGDAWHLPHGAYATLTVLKDAGVKVAVVSNFDTRLRKLLKDLNVLDMFDAVIISAEVGYEKPDGQIFEAALDQLGVTSNKAVHVGDDQKADKEGANAVGIACW
LWGTDVTTFQDVQNRILVRDSSF

Tan0012612 (gene) of Snake gourd v1 genome