CuGenDBv2

Gene ID	Tan0012981
Organism	Trichosanthes anguina (Snake gourd v1)
Description	insulin-degrading enzyme-like 1, peroxisomal
Genome location	LG08:56179347..56259544
RNA-Seq Expression	Tan0012981
Synteny	Tan0012981
Gene Ontology terms	GO:0006508 - proteolysis (biological process) GO:0004222 - metalloendopeptidase activity (molecular function) GO:0046872 - metal ion binding (molecular function)
InterPro domains	IPR007863 - Peptidase M16, C-terminal IPR011249 - Metalloenzyme, LuxS/M16 peptidase-like IPR032632 - Peptidase M16, middle/third domain

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAG6580840.1 Insulin-degrading enzyme-like 1, peroxisomal, partial [Cucurbita argyrosperma subsp. sororia]

0.0e+00

88.89

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGNWDTLEVQPKAKGLDTR ELLKFY+NNYSSN+MHLVVY+KENLDKVQ LVEN FQDIPN+NCN ANFPGQPC SEHLQVLVRAIPIKQGHKLRIVWPI
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
        TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKV IDLTDVGQEHMQDVVGLLFKYISLLK+SGIC+WIFDELSAICE
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
        TKFHYQDKIRPIDYVVNLSLNMQ +                          + ++N  IFWESK FEGKTDKVE+WYGTAYSIEKISGP IQ+W++SAPD
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
        VKL+LPA N+FIPTDLSLK ACEK EFPILLRKSSYSTIWYKPDTMFFTPKAYVK+DFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
Subjt:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI

Query:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL
        +PADSGFQVTLIGYNHKLRILLETIV+KIA FSVK DRFLVIKETV+KEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKF PTLL
Subjt:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL

Query:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK
        SSAYLECYIAGNIER ESE+MI HIED FFKG NPISRPLYPSQHPTNRVVKLERGI YFYSAEGLNPNDENSALVHYIQV+RDDFLQNVKLQLFALVAK
Subjt:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK

Query:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT
        QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQST+KGPRNIDLRVE+FLE FEKKLV+MTI+EFKSNVNALVDMKLEKFKNLREESGFYWREI DGT
Subjt:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT

Query:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
        +KFDRRESEVAALKT+THQ+LI+FFNEHIKVGAP K++LSVRVYGNLHSSEYS DL++P+QPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
Subjt:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL

XP_022934728.1 insulin-degrading enzyme-like 1, peroxisomal [Cucurbita moschata]

0.0e+00

88.76

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGNWDTLEVQPKAKGLDTR ELLKFY+NNYSSN+MHLVVY+KENLDKVQ LVEN FQDIPN+NCN ANFPGQPC SEHLQVLVRAIPIKQGHKLRIVWPI
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
        TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKV IDLTDVGQEHMQDVVGLLFKYISLLK+SGIC+WIFDELSAICE
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
        TKFHYQDKIRPIDYVVNLSLNMQ +                          + ++N  IFWESK FEGKTD+VE+WYGTAYSIEKISGP IQ+W++SAPD
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
        VKL+LPA N+FIPTDLSLK ACEK EFPILLRKSSYSTIWYKPDTMFFTPKAYVK+DFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
Subjt:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI

Query:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL
        +PADSGFQVTLIGYNHKLRILLETIV+KIAKFSVK DRFLVIKETV+KEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKF PTLL
Subjt:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL

Query:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK
        SSAYLECYIAGNIER ESE+MI HIED FFKG NPISRPLYPSQHPTNRVVKLERGI YFYSAEGLN NDENSALVHYIQV+RDDFLQNVKLQLFALVAK
Subjt:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK

Query:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT
        QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQST+KGPRNIDLRVE+FLE FEKKLV+MTI+EFKSNVNALVDMKLEKFKNLREESGFYWREI DGT
Subjt:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT

Query:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
        +KFDRRESEVAALKT+THQ+LI+FFNEHIKVGAP K++LSVRVYGNLHSSEYS DL++P+QPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
Subjt:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL

XP_022982829.1 insulin-degrading enzyme-like 1, peroxisomal [Cucurbita maxima]

0.0e+00

88.64

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGNWDTLEVQPKAKGLDTR ELLKFYENNYSSN+MHLVVY+KENLDKVQ+LVEN FQDIPN+NCN ANFPGQPC SEHLQVLVRAIPIKQGHKLRIVWPI
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
        +PEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKV IDLTDVGQEHMQDVVGLLFKYISLLK+SGIC+WIFDELSAICE
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
        TKFHYQDKIRPIDYVVNLSLNMQ +                          + ++N  IFWESK FEGKTDKVE+WYGTAYSIEKISGP IQ+W++SAPD
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
        VKL+LPA N+FIPTDLSLK ACEK EFPILLRKSSYSTIWYKPDTMFFTPKAYVK+DFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
Subjt:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI

Query:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL
        +PADSGFQVTLIGYNHKLRILLETIV+KIA FSVK DRFLVIKETV+KEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKF PTLL
Subjt:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL

Query:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK
        SSAYLECYIAGNIER ESE+MI HIED FFKG NPISRPLYPSQHPTNRVVKLERGI YFYSAEGLNPNDENSALVHYIQV+RDDFLQNVKLQLFALVAK
Subjt:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK

Query:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT
        QAAFHQLRTVEQLGYITVLMQRND GIRGVQF+IQST+KGPRNIDLRVE+FLE FEKKLV+MTI+EFKSNVNALVDMKLEKFKNLREESGFYWREI DGT
Subjt:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT

Query:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
        +KFDRRESEVAALKT+THQ+LI+FFNEHIKVGAP K++LSVRVYGNLHSSEYS DL++P+QPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
Subjt:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL

XP_023526970.1 insulin-degrading enzyme-like 1, peroxisomal [Cucurbita pepo subsp. pepo]

0.0e+00

88.76

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGNWDTLEVQPKAKGLDTR ELLKFY+NNYSSN+MHLVVY+KENLDKVQ LVEN FQDIPN+NCN ANFPGQPC SEHLQVLVRAIPIKQGHKLRIVWPI
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
        TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKV IDLTDVGQEHMQDVVGLLFKYISLLK+SGIC+WIFDELSAICE
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
        TKFHYQDKIRPIDYVVNLSLNMQ +                          + ++N  IFWESK FEGKTDKVE+WYGTAYSIEKISGP IQ+W++SAPD
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
        VKL+LPA N+FIPTDLSLK ACEK EFPILLRKSSYSTIWYKPDTMFFTPKAYVK+DFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
Subjt:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI

Query:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL
        +PADSGFQVTLIGYNHKLRILLETIV+KIA FSVK DRFLVIKETV+KEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKF PTLL
Subjt:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL

Query:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK
        SSAYLECYIAGNIER ESE+MI HIED FFKG NPISRPLYPSQHPTNRVVKLERGI YFYSAEGLNPNDENSALVHYIQV+RDDFLQNVKLQLFALVAK
Subjt:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK

Query:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT
        QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQST+KGPRNIDLRVE+FLE FEKKLV+MTI+EFKSNVNALVDMKLEKFKNLREESGFYWREI DGT
Subjt:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT

Query:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
        +KFDRRESEVAALKT+THQ+LI+FFNEHIKVGA  K++LSVRVYGNLHSSEYS DL++P+QPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
Subjt:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL

XP_038905747.1 insulin-degrading enzyme-like 1, peroxisomal isoform X1 [Benincasa hispida]

0.0e+00

87.25

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGNWDTLEVQPKAKGLDTR ELLKFY+NNYSSN+MHLVVYSKE LDKVQ+LVEN FQDIPNHNCN ANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
        TPEIHHYKEGPCRYL HLIGHEGEGSLYYVLKTLGWATGLSAG+SDST+NFSFFKVVIDLTDVGQEHMQD++GLLFKYISLLKQSG+C+WIFDELSAICE
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
        TKFHYQDKIRPIDYVVNLSLNMQ++                          + ++N  IFWESKKFEG+TDKVE+WYGTAYS+EKIS P IQ+WMRSAPD
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
        VKL+LPA NIFIPTDLSLK ACEK +FP LLR SSYSTIWYKPDTMF TPKAYVK+DFKCPHADISPEAEVLT IFTRLLMDYLNEYAY+AQVAGLYYGI
Subjt:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI

Query:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL
        NPADSGFQVTLIGYNHKLRILLETIV+KIAKFSVK DRFLVIKETV+KEYQNFKFQ+PYQQALYYCSLIL+DH+WPLMEEL ILPHL AEDL KFVPTLL
Subjt:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL

Query:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK
        SSAYLEC+IAGNIER E+ESMI HIED FFKGPNPI RPLYPSQHP NRVVKL+RGISYFYSAEGLNPNDENSALVHYIQV+RD+FLQNVKLQLFA VAK
Subjt:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK

Query:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT
        QAAFHQLRTVEQLGYITVL+QRNDSGIRGVQFIIQST+KGPRNIDLRVEAFLE FEKKLVEMTIDEFKSNVNALVD KLEKFKNLREESGFYWREI DGT
Subjt:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT

Query:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
        LKFDRRESEVAALKT+THQ+LI+FFNEHIKVGAP KK+LSVRVYGNLHSSEYS DLN+P+QPDTVKIDD+F+FR SQPLYGSFKGAFGNVKL
Subjt:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL

TrEMBL top hits

e value

%identity

Alignment

A0A1S3B7B5 insulin-degrading enzyme-like 1, peroxisomal isoform X1

0.0e+00

84.22

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGNW+TLEVQPKAKGLDTR ELLKFYENNYSSN+MHLVVY+KE LDKVQ+LVEN FQDIPNHNCN ANFPGQPCTSEHLQVLVRAIPIK+GHKLRI+WPI
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
        TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQ+V+GLLF+YISLLKQSGIC+WIFDELSAICE
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
        TKFHY DKIRPI+YV++LSLNMQ++                          + ++N  IFWESKKFEGKTDKVE+WYGTAYSIEKISG  +Q+WM+SAPD
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
        V L+LPA NIFIPTDLSLK ACEK EFP+LLRKSSYS+IWYKPDTMF TPKAYVK+DF CPHADISPEAEVLT IFTRLLMDYLNEYAY A+VAGLYYGI
Subjt:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI

Query:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL
        N  DSGFQVTL GYNHKLR+LLETIV+KIAKFSVK DR+LVIKET++K+YQNFKFQ+PYQQALYYCSLIL+D TWPLM+ELAILPHLGA DL KFVPTLL
Subjt:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL

Query:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK
        SSAYLEC+IAGNIERTE+ESMI HIEDTFFKGPNPISRPL PSQ+P NR+VKLERGI Y YSAEGLN NDENSALVHYIQV+RD+FLQNVKLQLFA VAK
Subjt:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK

Query:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT
        QAAFHQLRTVEQLGYITVL Q N  GIRGVQFIIQST+KGPR IDLRVEAFL+ FEKKLVEMTIDEFKSNVNALVD KLEKFKNL+EES FYW EI  GT
Subjt:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT

Query:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
        LKFDRRESEVA LKT+THQ+LI+FFNEHIKVGAP KK+LSVRVYGNLHSSEYS DLN+P+QP+TVKIDDIFSFRRSQPLYGSFKGA+GNVKL
Subjt:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL

A0A6J1DJ48 insulin-degrading enzyme-like 1, peroxisomal isoform X1

0.0e+00

86.74

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGNWDTLEVQPKAKGLDTR EL++F+E NYSSNIMHLVVY+KENLDKVQ LVEN FQDIPNHNCN A+FPGQPCTSEHL+VLVRAIPIKQGHKLRIVWPI
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
        TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDST NFSFFKV+IDLTD GQEHMQD+VGLLFKYI LLKQSGIC+WIFDELSAICE
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
        TKFHYQDKIRPIDYVVNLSLNMQ++                          + + N  IFWESKKFEG+TDKVE WYGT YSIE ISG  IQEWM SAPD
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
        VKL+LPAPNIFIPTDLSLKDA EK EFP+LLRKSSYST+WYKPDTMFFTPKAYVK+DF+CPHA ISPEAEVLT+IFTRLLMDYLNEYAYSAQVAGLYYGI
Subjt:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI

Query:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL
        NP ++GFQVTLIGYNHKLR+LLET+V+KIA+F+VK DRFLVIKETVMKEYQNFKFQ+PYQQA+YYCSLILQDHTWPLMEELAILPHLGAEDLVKF PTLL
Subjt:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL

Query:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK
        SSA LECYIAGNIER ESESMI HIED FFKGPNPISRPLYPSQHPTNRVVKL RGI YFYSAEGLNPNDENSALVHYIQV+RDDFLQNVKLQLFALVAK
Subjt:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK

Query:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT
        Q+AFHQLRTVEQLGYIT LMQRNDSGIRG+QFIIQST KGPRNIDLRVEAFLE FE KLV+MTIDEFKSNVNAL+DMKLEKFKNLREESGFYWREI DGT
Subjt:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT

Query:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
        LKFDRRESEVA L+T+ HQELI+FFNEHIKVGAPHKKALSVRVYGNLHSSEYS+DL++P+QPDTVKIDDIFSFRRSQPLYGSFKGAFG+VKL
Subjt:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL

A0A6J1DJV0 insulin-degrading enzyme-like 1, peroxisomal isoform X2

0.0e+00

86.74

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGNWDTLEVQPKAKGLDTR EL++F+E NYSSNIMHLVVY+KENLDKVQ LVEN FQDIPNHNCN A+FPGQPCTSEHL+VLVRAIPIKQGHKLRIVWPI
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
        TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDST NFSFFKV+IDLTD GQEHMQD+VGLLFKYI LLKQSGIC+WIFDELSAICE
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
        TKFHYQDKIRPIDYVVNLSLNMQ++                          + + N  IFWESKKFEG+TDKVE WYGT YSIE ISG  IQEWM SAPD
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
        VKL+LPAPNIFIPTDLSLKDA EK EFP+LLRKSSYST+WYKPDTMFFTPKAYVK+DF+CPHA ISPEAEVLT+IFTRLLMDYLNEYAYSAQVAGLYYGI
Subjt:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI

Query:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL
        NP ++GFQVTLIGYNHKLR+LLET+V+KIA+F+VK DRFLVIKETVMKEYQNFKFQ+PYQQA+YYCSLILQDHTWPLMEELAILPHLGAEDLVKF PTLL
Subjt:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL

Query:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK
        SSA LECYIAGNIER ESESMI HIED FFKGPNPISRPLYPSQHPTNRVVKL RGI YFYSAEGLNPNDENSALVHYIQV+RDDFLQNVKLQLFALVAK
Subjt:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK

Query:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT
        Q+AFHQLRTVEQLGYIT LMQRNDSGIRG+QFIIQST KGPRNIDLRVEAFLE FE KLV+MTIDEFKSNVNAL+DMKLEKFKNLREESGFYWREI DGT
Subjt:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT

Query:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
        LKFDRRESEVA L+T+ HQELI+FFNEHIKVGAPHKKALSVRVYGNLHSSEYS+DL++P+QPDTVKIDDIFSFRRSQPLYGSFKGAFG+VKL
Subjt:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL

A0A6J1F8G9 insulin-degrading enzyme-like 1, peroxisomal

0.0e+00

88.76

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGNWDTLEVQPKAKGLDTR ELLKFY+NNYSSN+MHLVVY+KENLDKVQ LVEN FQDIPN+NCN ANFPGQPC SEHLQVLVRAIPIKQGHKLRIVWPI
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
        TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKV IDLTDVGQEHMQDVVGLLFKYISLLK+SGIC+WIFDELSAICE
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
        TKFHYQDKIRPIDYVVNLSLNMQ +                          + ++N  IFWESK FEGKTD+VE+WYGTAYSIEKISGP IQ+W++SAPD
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
        VKL+LPA N+FIPTDLSLK ACEK EFPILLRKSSYSTIWYKPDTMFFTPKAYVK+DFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
Subjt:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI

Query:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL
        +PADSGFQVTLIGYNHKLRILLETIV+KIAKFSVK DRFLVIKETV+KEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKF PTLL
Subjt:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL

Query:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK
        SSAYLECYIAGNIER ESE+MI HIED FFKG NPISRPLYPSQHPTNRVVKLERGI YFYSAEGLN NDENSALVHYIQV+RDDFLQNVKLQLFALVAK
Subjt:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK

Query:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT
        QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQST+KGPRNIDLRVE+FLE FEKKLV+MTI+EFKSNVNALVDMKLEKFKNLREESGFYWREI DGT
Subjt:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT

Query:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
        +KFDRRESEVAALKT+THQ+LI+FFNEHIKVGAP K++LSVRVYGNLHSSEYS DL++P+QPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
Subjt:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL

A0A6J1J5M2 insulin-degrading enzyme-like 1, peroxisomal

0.0e+00

88.64

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGNWDTLEVQPKAKGLDTR ELLKFYENNYSSN+MHLVVY+KENLDKVQ+LVEN FQDIPN+NCN ANFPGQPC SEHLQVLVRAIPIKQGHKLRIVWPI
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
        +PEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKV IDLTDVGQEHMQDVVGLLFKYISLLK+SGIC+WIFDELSAICE
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
        TKFHYQDKIRPIDYVVNLSLNMQ +                          + ++N  IFWESK FEGKTDKVE+WYGTAYSIEKISGP IQ+W++SAPD
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
        VKL+LPA N+FIPTDLSLK ACEK EFPILLRKSSYSTIWYKPDTMFFTPKAYVK+DFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
Subjt:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI

Query:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL
        +PADSGFQVTLIGYNHKLRILLETIV+KIA FSVK DRFLVIKETV+KEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKF PTLL
Subjt:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL

Query:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK
        SSAYLECYIAGNIER ESE+MI HIED FFKG NPISRPLYPSQHPTNRVVKLERGI YFYSAEGLNPNDENSALVHYIQV+RDDFLQNVKLQLFALVAK
Subjt:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK

Query:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT
        QAAFHQLRTVEQLGYITVLMQRND GIRGVQF+IQST+KGPRNIDLRVE+FLE FEKKLV+MTI+EFKSNVNALVDMKLEKFKNLREESGFYWREI DGT
Subjt:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT

Query:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
        +KFDRRESEVAALKT+THQ+LI+FFNEHIKVGAP K++LSVRVYGNLHSSEYS DL++P+QPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
Subjt:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL

SwissProt top hits

e value

%identity

Alignment

F4J3D9 Insulin-degrading enzyme-like 2

2.3e-286

61.99

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGN DTL V+P+  G+DTR EL+KFY+ +YS+NIMHLVVY KENLDK Q LVE  FQ I N N     FPGQPCT +HLQVLV+A+PI QGH+L + WP+
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
        TP I HY+E PCRYLG LIGHEGEGSL++ LK LGWATGL AGE+D +M +SFF V IDLTD G EHMQD++GLLF+YI +L+QSG+ +WIFDELSAICE
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
         +FHYQ KI PI Y V++S NM+++                          +  NN  IFWES KFEG+TDKVE WY TAYS+EKI+  +IQEWM+SAPD
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
        V L LP PN+FIPTD SLKD  +K  FP+LLRK+SYS +WYKPDT FF PKAYVK+DF CP A  SP+A VL++IF  LL+DYLNEYAY AQ AGL YG+
Subjt:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI

Query:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL
        + +D+GF+++L G+NHKLRILLE ++QKIAKF VK DRF VIKETV K YQN KFQ+P++QA  YCSL+LQD  WP  EEL  L HL AEDL  FVP LL
Subjt:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL

Query:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK
        S  ++ECYIAGN+E+ E+ESM+ HIED  F    PI RPL+PSQ  TNRV +L  G+ +FY  EG N +DENSALVHYIQV++D+F  N KLQLF L+AK
Subjt:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK

Query:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT
        Q  FHQLRT+EQLGYIT L   NDSG+ GVQFIIQS++KGP +ID RVE+ L+  E K   M+ +EFKSNV  L+DMKLEK KNL EES FYW EI  GT
Subjt:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT

Query:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFK
        LKF+R ++EVAAL+ +   E IDFF+E+IKV AP+KK+LS+ VYGN H  E   D  + I   +++I+DI  FR+SQPLYGS K
Subjt:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFK

O22941 Insulin-degrading enzyme-like 1, peroxisomal

0.0e+00

66.67

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGN DTL V+P+AKG+DTR EL+KFYE +YS+NIMHLVVY KE+LDK+Q LVE  FQ+I N N     FPGQPCT++HLQ+LV+AIPIKQGHKL + WP+
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
        TP IHHY E P +YLGHLIGHEGEGSL++ LKTLGWATGLSAGE + T+++SFFKV IDLTD G EHMQ+++GLLF YI LL+Q+G+C+WIFDELSAICE
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
        TKFHYQDKI P+ Y+V+++ NMQ++                          +  +N  IFWES+KFEG+TDK E WY TAYS+EKI+  +IQEW++SAPD
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
        V L+LPAPN+FIPTDLSLKDA +K   P+LLRK+ +S +WYKPDTMF  PKAYVK+DF CP A  SP+A VLT+IFTRLLMDYLNEYAY AQVAGLYYG+
Subjt:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI

Query:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL
        + +D+GF++TL+GYNHKLRILLET+V KIA F VK DRF VIKETV KEYQN+KF++PY QA+YYCSLILQD TWP  EEL +L HL AED+ KFVP LL
Subjt:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL

Query:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK
        S  ++ECYIAGN+E  E+ESM+ HIED  F  P PI RPL+PSQH TNRVVKL  G+ YFY  +G NP+DENSALVHYIQV+RDDF  N+KLQLF LVAK
Subjt:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK

Query:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT
        QA FHQLRTVEQLGYIT L QRNDSGI GVQFIIQS++KGP +ID RVE+ L+ FE KL EM+ ++FKSNV AL+DMKLEK KNL+EES FYWREI  GT
Subjt:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT

Query:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
        LKF+R+E+EV+ALK +  QELIDFF+E+IKVGA  KK+LS+RVYG+ H  E ++D +E   P +V+I+DI  FR+SQPL+GSF+G  G  KL
Subjt:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL

P14735 Insulin-degrading enzyme

3.5e-133

35.48

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGN  TLE +P  +G+D RQELLKF+   YSSN+M + V  +E+LD +  LV   F ++ N N     FP  P   EHL+ L + +PIK    L + +PI
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
             +YK  P  YLGHLIGHEG GSL   LK+ GW   L  G+ +    F FF + +DLT+ G  H++D++  +F+YI  L+  G  EW+F E   +  
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVFVI--LLNNHYIFWE-----------------------SKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
          F ++DK RP  Y   ++  +  + +  +L   Y+  E                       SK FEGKTD+ E WYGT Y  E I    I++W  +  +
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVFVI--LLNNHYIFWE-----------------------SKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEKA-EFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYG
         K  LP  N FIPT+  +    ++A  +P L++ ++ S +W+K D  FF PKA +  +F  P A + P    +  ++  LL D LNEYAY+A++AGL Y 
Subjt:  VKLYLPAPNIFIPTDLSLKDACEKA-EFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYG

Query:  INPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTL
        +     G  +++ GYN K  ILL+ I++K+A F +   RF +IKE  M+   NF+ ++P+Q A+YY  L++ +  W   E    L  +    L  F+P L
Subjt:  INPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTL

Query:  LSSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKL-ERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALV
        LS  ++E  + GNI +  +  ++  +EDT  +  +  ++PL PSQ    R V+L +RG   ++  +  N    N  +  Y Q +     +N+ L+LF  +
Subjt:  LSSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKL-ERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALV

Query:  AKQAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDD
          +  F+ LRT EQLGYI     R  +GI+G++FIIQS  K P  ++ RVEAFL T EK + +MT + F+ ++ AL   +L+K K L  E   YW EI  
Subjt:  AKQAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDD

Query:  GTLKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSS-------EYSTDLN---EPIQPDTVKIDDIFSFRRSQPLY
            FDR  +EVA LKT+T +++I F+ E + V AP +  +SV V      S           D+N    P  P    I ++  F+R  PL+
Subjt:  GTLKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSS-------EYSTDLN---EPIQPDTVKIDDIFSFRRSQPLY

P35559 Insulin-degrading enzyme

5.0e-132

35.44

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGN  TLE +P  +G+D R+ELLKF+   YSSN+M + V  +E+LD +  LV   F ++ N N     FP  P   EHL+ L + +PIK    L + +PI
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
             +YK  P  YLGHLIGHEG GSL   LK+ GW   L  G+ +    F FF + +DLT+ G  H++D++  +F+YI  L+  G  EW+F E   +  
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVFVI--LLNNHYIFWE-----------------------SKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
          F ++DK RP  Y   ++  +  + +  +L   Y+  E                       SK FEGKTD+ E+WYGT Y  E I    IQ+W  +  +
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVFVI--LLNNHYIFWE-----------------------SKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEK--AEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYY
         K  LP  N FIPT+  +  A EK    +P L++ ++ S +W+K D  FF PKA +  +F  P A + P    +  ++  LL D LNEYAY+A++AGL Y
Subjt:  VKLYLPAPNIFIPTDLSLKDACEK--AEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYY

Query:  GINPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPT
         +     G  +++ GYN K  ILL+ I +K+A F +   RF +IKE  M+   NF+ ++P+Q A+YY  L++ +  W   E    L  +    L  F+P 
Subjt:  GINPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPT

Query:  LLSSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKL-ERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFAL
        LLS  ++E  + GNI +  +  ++  +EDT  +  +  ++PL PSQ    R V+L +RG   ++  +  N    N  +  Y Q +     +N+ L+LF  
Subjt:  LLSSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKL-ERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFAL

Query:  VAKQAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREID
        +  +  F+ LRT EQLGYI     R  +GI+G++FIIQS  K P  ++ RVEAFL T EK + +MT + F+ ++ AL   +L+K K L  E   YW EI 
Subjt:  VAKQAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREID

Query:  DGTLKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSS-------EYSTDLN---EPIQPDTVKIDDIFSFRRSQPLY
             +DR   EVA LKT++  ++I F+ E + V AP +  +SV V      S           D+N    P  P    I ++  F+R  PL+
Subjt:  DGTLKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSS-------EYSTDLN---EPIQPDTVKIDDIFSFRRSQPLY

Q24K02 Insulin-degrading enzyme

4.5e-133

35.77

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGN  TLE +P  +G+D RQELLKF+   YSSN+M + V  +E+LD +  LV   F ++ N N     FP  P   EHL+ L + +PIK    L + +PI
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
             +YK  P  YLGHLIGHEG GSL   LK+ GW   L  G+ +    F FF + +DLT+ G  H++D++  +F+YI  L+  G  EW+F E   +  
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVFVI--LLNNHYIFWE-----------------------SKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
          F ++DK RP  Y   ++  +  + +  +L   Y+  E                       SK FEGKTD+ E WYGT Y  E I    I++W  +  +
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVFVI--LLNNHYIFWE-----------------------SKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTD---LSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLY
         K  LP  N FIPT+   LSL+   E   +P L++ ++ S +W+K D  FF PKA +  +F  P A + P    +  ++  LL D LNEYAY+A++AGL 
Subjt:  VKLYLPAPNIFIPTD---LSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLY

Query:  YGINPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVP
        Y +     G  +++ GYN K  ILL+ I++K+A F +   RF +IKE  M+   NF+ ++P+Q A+YY  L++ +  W   E    L  +    L  F+P
Subjt:  YGINPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVP

Query:  TLLSSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKL-ERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFA
         LLS  ++E  + GNI +  +  ++  +EDT  +  +  ++PL PSQ    R V+L +RG   ++  +  N    N  +  Y Q +     +N+ L+LF 
Subjt:  TLLSSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKL-ERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFA

Query:  LVAKQAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREI
         +  +  F+ LRT EQLGYI     R  +GI+G++FIIQS  K P  ++ RVEAFL T EK + +MT + F+ ++ AL   +L+K K L  E   YW EI
Subjt:  LVAKQAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREI

Query:  DDGTLKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSS-------EYSTDLN---EPIQPDTVKIDDIFSFRRSQPLY
              FDR   EVA LKT+T +++I F+ E + V AP +  +SV V      S           D+N    P  P    I ++  F+R  PL+
Subjt:  DDGTLKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSS-------EYSTDLN---EPIQPDTVKIDDIFSFRRSQPLY

Arabidopsis top hits

e value

%identity

Alignment

AT1G06900.1 Insulinase (Peptidase family M16) family protein

4.1e-81

28.19

Show/hide

Query:  GLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPITPEIHHYKEGPCRY
        G+D R+ ++K Y+  Y   +M LVV   E+LD ++  V   F D+ N +        +    +  + L R   +K  H L + W + P    Y + P  Y
Subjt:  GLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPITPEIHHYKEGPCRY

Query:  LGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFS----FFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICETKFHYQDKIR
        L HL+GHEG GSL+  LK  GWAT LSAG  D  +N S     F + I LTD G E + D++G +++Y+ LL+     EWIF EL  I    F + ++  
Subjt:  LGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFS----FFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICETKFHYQDKIR

Query:  PIDYVVNLSLNMQVFVI--LLNNHYIF--WE---------------------SKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMR-SAPDVKLYLPAPN
          DY   LS NM  + +  ++   Y++  W+                     SK  + +  + E W+G++Y  E +    ++ W   S  D  L+LP+ N
Subjt:  PIDYVVNLSLNMQVFVI--LLNNHYIF--WE---------------------SKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMR-SAPDVKLYLPAPN

Query:  IFIPTDLSLK----DACEKAEF-PILLRKSSYSTIWYKPDTMFFTPKA--YVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGINP
         FIP D S++    D   K++  P  +    +   WYK D  F  P+A  Y +++ K  +A +  +  +LTE++  LL D LNE  Y A +A L   ++ 
Subjt:  IFIPTDLSLK----DACEKAEF-PILLRKSSYSTIWYKPDTMFFTPKA--YVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGINP

Query:  ADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLLSS
             ++ + G+N K+  LL  I+     F   L+RF VIKE + + ++N    KP   + Y    +L    +   E+L++L  L  +DL  F+P L S 
Subjt:  ADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLLSS

Query:  AYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQ---NVKLQLFALVA
         ++E    GN+   E+ ++    +D+    P P S+  +  Q     +     G          N ++ NS +  Y Q+  ++         L LF  + 
Subjt:  AYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQ---NVKLQLFALVA

Query:  KQAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDG
        ++  F+QLRT EQLGY+     R    + G  F +QS+  GP ++  RV+ F++  E  L ++  + ++   + ++   LEK  +L  E+   W +I D 
Subjt:  KQAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDG

Query:  TLKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYG-NLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGS
           FD    E   L++I  +++I ++  + +  +P  + L+VRV+G + +  E  TD     Q     I D  +F+ +   Y S
Subjt:  TLKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYG-NLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGS

AT2G41790.1 Insulinase (Peptidase family M16) family protein

0.0e+00

66.67

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGN DTL V+P+AKG+DTR EL+KFYE +YS+NIMHLVVY KE+LDK+Q LVE  FQ+I N N     FPGQPCT++HLQ+LV+AIPIKQGHKL + WP+
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
        TP IHHY E P +YLGHLIGHEGEGSL++ LKTLGWATGLSAGE + T+++SFFKV IDLTD G EHMQ+++GLLF YI LL+Q+G+C+WIFDELSAICE
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
        TKFHYQDKI P+ Y+V+++ NMQ++                          +  +N  IFWES+KFEG+TDK E WY TAYS+EKI+  +IQEW++SAPD
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
        V L+LPAPN+FIPTDLSLKDA +K   P+LLRK+ +S +WYKPDTMF  PKAYVK+DF CP A  SP+A VLT+IFTRLLMDYLNEYAY AQVAGLYYG+
Subjt:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI

Query:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL
        + +D+GF++TL+GYNHKLRILLET+V KIA F VK DRF VIKETV KEYQN+KF++PY QA+YYCSLILQD TWP  EEL +L HL AED+ KFVP LL
Subjt:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL

Query:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK
        S  ++ECYIAGN+E  E+ESM+ HIED  F  P PI RPL+PSQH TNRVVKL  G+ YFY  +G NP+DENSALVHYIQV+RDDF  N+KLQLF LVAK
Subjt:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK

Query:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT
        QA FHQLRTVEQLGYIT L QRNDSGI GVQFIIQS++KGP +ID RVE+ L+ FE KL EM+ ++FKSNV AL+DMKLEK KNL+EES FYWREI  GT
Subjt:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT

Query:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL
        LKF+R+E+EV+ALK +  QELIDFF+E+IKVGA  KK+LS+RVYG+ H  E ++D +E   P +V+I+DI  FR+SQPL+GSF+G  G  KL
Subjt:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFKGAFGNVKL

AT3G57470.1 Insulinase (Peptidase family M16) family protein

2.6e-248

62.57

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGN DTL V+P+  G+DTR EL+KFY+ +YS+NIMHLVVY KENLDK Q LVE  FQ I N N     FPGQPCT +HLQVLV+A+PI QGH+L + WP+
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
        TP I HY+E PCRYLG LIGHEGEGSL++ LK LGWATGL AGE+D +M +SFF V IDLTD G EHMQD++GLLF+YI +L+QSG+ +WIFDELSAICE
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
         +FHYQ KI PI Y V++S NM+++                          +  NN  IFWES KFEG+TDKVE WY TAYS+EKI+  +IQEWM+SAPD
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
        V L LP PN+FIPTD SLKD  +K  FP+LLRK+SYS +WYKPDT FF PKAYVK+DF CP A  SP+A VL++IF  LL+DYLNEYAY AQ AGL YG+
Subjt:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI

Query:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL
        + +D+GF+++L G+NHKLRILLE ++QKIAKF VK DRF VIKETV K YQN KFQ+P++QA  YCSL+LQD  WP  EEL  L HL AEDL  FVP LL
Subjt:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL

Query:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK
        S  ++ECYIAGN+E+ E+ESM+ HIED  F    PI RPL+PSQ  TNRV +L  G+ +FY  EG N +DENSALVHYIQV++D+F  N KLQLF L+AK
Subjt:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK

Query:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFK
        Q  FHQLRT+EQLGYIT L   NDSG+ GVQFIIQS++KGP +ID RVE+ L+  E K   M+ +EFK
Subjt:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFK

AT3G57470.2 Insulinase (Peptidase family M16) family protein

1.6e-287

61.99

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGN DTL V+P+  G+DTR EL+KFY+ +YS+NIMHLVVY KENLDK Q LVE  FQ I N N     FPGQPCT +HLQVLV+A+PI QGH+L + WP+
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
        TP I HY+E PCRYLG LIGHEGEGSL++ LK LGWATGL AGE+D +M +SFF V IDLTD G EHMQD++GLLF+YI +L+QSG+ +WIFDELSAICE
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
         +FHYQ KI PI Y V++S NM+++                          +  NN  IFWES KFEG+TDKVE WY TAYS+EKI+  +IQEWM+SAPD
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
        V L LP PN+FIPTD SLKD  +K  FP+LLRK+SYS +WYKPDT FF PKAYVK+DF CP A  SP+A VL++IF  LL+DYLNEYAY AQ AGL YG+
Subjt:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI

Query:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL
        + +D+GF+++L G+NHKLRILLE ++QKIAKF VK DRF VIKETV K YQN KFQ+P++QA  YCSL+LQD  WP  EEL  L HL AEDL  FVP LL
Subjt:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL

Query:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK
        S  ++ECYIAGN+E+ E+ESM+ HIED  F    PI RPL+PSQ  TNRV +L  G+ +FY  EG N +DENSALVHYIQV++D+F  N KLQLF L+AK
Subjt:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK

Query:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT
        Q  FHQLRT+EQLGYIT L   NDSG+ GVQFIIQS++KGP +ID RVE+ L+  E K   M+ +EFKSNV  L+DMKLEK KNL EES FYW EI  GT
Subjt:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT

Query:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFK
        LKF+R ++EVAAL+ +   E IDFF+E+IKV AP+KK+LS+ VYGN H  E   D  + I   +++I+DI  FR+SQPLYGS K
Subjt:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFK

AT3G57470.3 Insulinase (Peptidase family M16) family protein

6.7e-281

61.1

Show/hide

Query:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI
        TGN DTL V+P+  G+DTR EL+KFY+ +YS+NIMHLVVY KENLDK Q LVE  FQ I N N     FPGQPCT +HLQVLV+A+PI QGH+L + WP+
Subjt:  TGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIPIKQGHKLRIVWPI

Query:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE
        TP I HY+E PCRYLG LIGHEGEGSL++ LK LGWATGL AGE+D +M +SFF V IDLTD G EHMQD++GLLF+YI +L+QSG+ +WIFDELSAICE
Subjt:  TPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSAICE

Query:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD
         +FHYQ KI PI Y V++S NM+++                          +  NN  IFWES KFEG+TDKVE WY TAYS+EKI+  +IQEWM+SAPD
Subjt:  TKFHYQDKIRPIDYVVNLSLNMQVF-------------------------VILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPD

Query:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI
        V L LP PN+FIPTD SLKD  +K  FP+LLRK+SYS +WYKPDT FF PKAYVK+DF CP A  SP+A VL++IF  LL+DYLNEYAY AQ AGL YG+
Subjt:  VKLYLPAPNIFIPTDLSLKDACEKAEFPILLRKSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGI

Query:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL
        + +D+GF+++L G+NHKLRILLE ++QKIAKF VK DRF VIKETV K YQN KFQ+P++QA  YCSL+LQD  WP  EEL  L HL AEDL  FVP LL
Subjt:  NPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVIKETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLL

Query:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK
        S  ++ECYIAGN+E+ E+ESM+ HIED  F    PI RPL+PSQ  TNRV +L  G+ +FY  EG N +DENSALVHYIQV++D+F  N KLQLF L+AK
Subjt:  SSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVKLERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAK

Query:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT
        Q  FHQLRT+EQLGYIT L   NDSG+ GVQFIIQS++KGP +ID RVE+ L+  E K   M+ +EF          KLEK KNL EES FYW EI  GT
Subjt:  QAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEMTIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGT

Query:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFK
        LKF+R ++EVAAL+ +   E IDFF+E+IKV AP+KK+LS+ VYGN H  E   D  + I   +++I+DI  FR+SQPLYGS K
Subjt:  LKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFSFRRSQPLYGSFK

Sequences

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CDS sequence

Show/hide CDS sequence

ATGAACATGTTTTTTGTAAGAAATTTTAAGGCTACTAGTTTCCTTATTGTGCTAGATATTTTTACTTGCACAGGGAATTGGGACACTTTGGAGGTTCAACCAAAAGCTAA
AGGGCTGGATACAAGACAGGAACTTCTAAAATTCTATGAAAATAATTATTCATCCAATATCATGCATCTTGTCGTATATTCAAAAGAAAACCTTGATAAAGTACAAATGC
TAGTGGAAAACACATTTCAAGATATTCCAAATCATAACTGCAATTATGCTAATTTTCCTGGTCAGCCATGCACGTCAGAACATCTTCAGGTTCTTGTTAGAGCCATCCCA
ATTAAACAAGGTCATAAATTGAGAATCGTTTGGCCAATAACTCCTGAAATTCATCATTACAAGGAAGGGCCATGCCGGTATCTAGGTCATCTTATTGGCCATGAAGGAGA
AGGATCCTTGTATTACGTTCTTAAAACATTAGGGTGGGCAACAGGGCTCTCAGCCGGTGAATCTGATTCCACCATGAATTTTTCCTTTTTCAAAGTAGTAATAGATCTCA
CTGATGTTGGTCAAGAACACATGCAAGATGTTGTTGGGCTGCTCTTTAAATACATTAGCCTTTTGAAGCAATCTGGTATATGCGAATGGATATTTGATGAGCTTTCAGCT
ATTTGTGAGACGAAGTTCCATTATCAAGATAAAATTCGTCCAATTGACTATGTAGTCAATCTGTCATTAAACATGCAGGTATTTGTAATCCTTCTGAATAATCATTACAT
CTTTTGGGAGTCGAAGAAATTTGAAGGCAAGACTGATAAGGTTGAGCGGTGGTATGGAACTGCCTACTCCATTGAGAAAATTTCTGGCCCTTCGATTCAGGAATGGATGC
GATCTGCTCCTGATGTAAAATTGTACCTACCAGCTCCGAACATTTTTATCCCTACTGATTTATCACTTAAGGATGCATGTGAAAAGGCTGAGTTTCCAATTCTGTTAAGA
AAGTCATCATATTCGACAATATGGTACAAACCAGACACAATGTTCTTCACACCCAAGGCATATGTTAAGGTTGATTTTAAATGTCCCCATGCTGATATCTCACCTGAAGC
AGAAGTCCTAACGGAAATTTTCACTAGGTTATTGATGGATTATCTGAATGAATACGCTTATAGTGCTCAGGTTGCTGGACTATATTATGGCATAAATCCTGCTGACTCTG
GTTTCCAGGTGACTCTGATTGGCTACAACCACAAATTAAGGATTCTATTGGAAACTATTGTTCAAAAAATCGCAAAATTCAGTGTGAAACTTGATAGGTTTCTCGTCATC
AAGGAAACTGTGATGAAGGAGTACCAAAATTTCAAGTTTCAGAAGCCTTATCAGCAGGCTTTGTACTATTGTTCGTTAATACTTCAAGATCACACATGGCCATTGATGGA
GGAACTTGCAATCCTTCCACATTTGGGGGCTGAAGATCTAGTTAAATTTGTTCCCACTTTGCTCTCAAGTGCCTACTTGGAATGTTACATTGCAGGAAACATTGAAAGGA
CTGAATCTGAATCAATGATCGCACACATTGAAGATACGTTCTTCAAGGGGCCAAATCCAATATCACGACCATTATATCCATCACAGCATCCAACCAATAGAGTTGTGAAG
CTTGAGAGAGGCATTAGTTACTTTTATTCAGCAGAGGGTCTCAATCCAAATGATGAAAATTCAGCTCTTGTCCACTATATTCAGGTGAATCGAGATGATTTTCTACAGAA
TGTGAAGCTTCAGCTTTTTGCTCTTGTCGCAAAACAAGCAGCATTTCATCAGCTTAGAACTGTTGAACAACTTGGCTATATTACTGTTTTAATGCAAAGGAATGACTCTG
GTATACGTGGAGTTCAATTTATTATTCAATCCACTATCAAGGGTCCTCGAAATATTGATTTGAGAGTAGAAGCGTTCCTAGAGACGTTTGAGAAGAAGCTCGTTGAGATG
ACAATTGATGAATTCAAGAGCAATGTAAATGCTCTAGTAGATATGAAGCTTGAGAAATTCAAGAACTTGAGGGAAGAATCTGGATTTTACTGGCGAGAGATTGATGATGG
GACACTGAAATTCGATAGGAGAGAATCAGAGGTTGCAGCATTAAAGACAATCACACATCAGGAATTGATCGACTTCTTCAATGAACATATAAAAGTTGGTGCACCTCATA
AGAAGGCTTTAAGTGTTCGGGTTTACGGAAATCTTCATTCTTCAGAGTACTCTACAGATTTAAATGAACCAATCCAACCAGACACAGTAAAAATAGATGATATTTTCAGT
TTCAGAAGATCACAGCCACTTTATGGCTCCTTCAAAGGAGCGTTTGGTAATGTGAAATTGTAG

mRNA sequence

Show/hide mRNA sequence

Protein sequence

Show/hide protein sequence

MNMFFVRNFKATSFLIVLDIFTCTGNWDTLEVQPKAKGLDTRQELLKFYENNYSSNIMHLVVYSKENLDKVQMLVENTFQDIPNHNCNYANFPGQPCTSEHLQVLVRAIP
IKQGHKLRIVWPITPEIHHYKEGPCRYLGHLIGHEGEGSLYYVLKTLGWATGLSAGESDSTMNFSFFKVVIDLTDVGQEHMQDVVGLLFKYISLLKQSGICEWIFDELSA
ICETKFHYQDKIRPIDYVVNLSLNMQVFVILLNNHYIFWESKKFEGKTDKVERWYGTAYSIEKISGPSIQEWMRSAPDVKLYLPAPNIFIPTDLSLKDACEKAEFPILLR
KSSYSTIWYKPDTMFFTPKAYVKVDFKCPHADISPEAEVLTEIFTRLLMDYLNEYAYSAQVAGLYYGINPADSGFQVTLIGYNHKLRILLETIVQKIAKFSVKLDRFLVI
KETVMKEYQNFKFQKPYQQALYYCSLILQDHTWPLMEELAILPHLGAEDLVKFVPTLLSSAYLECYIAGNIERTESESMIAHIEDTFFKGPNPISRPLYPSQHPTNRVVK
LERGISYFYSAEGLNPNDENSALVHYIQVNRDDFLQNVKLQLFALVAKQAAFHQLRTVEQLGYITVLMQRNDSGIRGVQFIIQSTIKGPRNIDLRVEAFLETFEKKLVEM
TIDEFKSNVNALVDMKLEKFKNLREESGFYWREIDDGTLKFDRRESEVAALKTITHQELIDFFNEHIKVGAPHKKALSVRVYGNLHSSEYSTDLNEPIQPDTVKIDDIFS
FRRSQPLYGSFKGAFGNVKL

Tan0012981 (gene) of Snake gourd v1 genome