CuGenDBv2

Gene ID	Tan0017574
Organism	Trichosanthes anguina (Snake gourd v1)
Description	Uricase
Genome location	LG01:112761284..112763006
RNA-Seq Expression	Tan0017574
Synteny	Tan0017574
Gene Ontology terms	GO:0006145 - purine nucleobase catabolic process (biological process) GO:0019628 - urate catabolic process (biological process) GO:0005777 - peroxisome (cellular component) GO:0004846 - urate oxidase activity (molecular function)
InterPro domains	IPR002042 - Uricase

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6573894.1 Uricase-2, partial [Cucurbita argyrosperma subsp. sororia]

1.0e-20

92.73

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Query:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI
        MA NVLSRFHV+SSVRLKMPNLHFLP+NISTKD+RSIVKFEDDVYLPTDEPHGSI
Subjt:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI

XP_022945092.1 uricase-2 isozyme 2-like [Cucurbita moschata]

1.0e-20

92.73

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Query:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI
        MA NVLSRFHV+SSVRLKMPNLHFLP+NISTKD+RSIVKFEDDVYLPTDEPHGSI
Subjt:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI

XP_022968310.1 uricase-2-like [Cucurbita maxima]

2.3e-20

90.91

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Query:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI
        MA NVLSRFHV+S+VRLKMPNLHFLP+NISTKD+RSIVKFEDDVYLPTDEPHGSI
Subjt:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI

XP_022983819.1 uricase-2 isozyme 2-like [Cucurbita maxima]

1.1e-19

90.91

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Query:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI
        MAKNVLSRFHV+SSVRLKMPNLHFLP NISTKD+RSIVKFE DVY+PTDEPHGSI
Subjt:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI

XP_023541764.1 uricase-2 isozyme 2 [Cucurbita pepo subsp. pepo]

1.0e-20

92.73

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Query:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI
        MA NVLSRFHV+SSVRLKMPNLHFLP+NISTKD+RSIVKFEDDVYLPTDEPHGSI
Subjt:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI

TrEMBL top hits

e value

%identity

Alignment

A0A5A7SZ15 Uricase

7.1e-20

89.09

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Query:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI
        MAKNVLSRF V+SSV+LKMPNLHFLP+NISTKD++SIVKFEDDVYLPTDEPHGSI
Subjt:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI

A0A5D3CBH0 Uricase

7.1e-20

89.09

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Query:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI
        MAKNVLSRF V+SSV+LKMPNLHFLP+NISTKD++SIVKFEDDVYLPTDEPHGSI
Subjt:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI

A0A6J1FZZ5 Uricase

4.9e-21

92.73

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Query:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI
        MA NVLSRFHV+SSVRLKMPNLHFLP+NISTKD+RSIVKFEDDVYLPTDEPHGSI
Subjt:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI

A0A6J1HWV6 Uricase

1.1e-20

90.91

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Query:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI
        MA NVLSRFHV+S+VRLKMPNLHFLP+NISTKD+RSIVKFEDDVYLPTDEPHGSI
Subjt:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI

A0A6J1J8L0 Uricase

5.4e-20

90.91

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Query:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI
        MAKNVLSRFHV+SSVRLKMPNLHFLP NISTKD+RSIVKFE DVY+PTDEPHGSI
Subjt:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI

SwissProt top hits

e value

%identity

Alignment

O04104 Uricase-2 isozyme 2

3.0e-15

74.55

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Query:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI
        MAK  L+RF  ++ V LKMPNLHFLP+NIS KD   IVKFEDDVYLPTDEPHGSI
Subjt:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI

O04420 Uricase

1.2e-16

70.91

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Query:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI
        M   VL RF  VSS+ LKMPN+HFLP+N+STK++ S+VKF+DDVYLPTDEPHGSI
Subjt:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI

P04670 Uricase-2 isozyme 1

3.3e-14

69.09

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Query:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI
        MAK  L+RF  ++ V LK+PNLHF+P+NIS +D   IVKFEDDVYLPTDEPHGSI
Subjt:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI

P34798 Uricase-2 isozyme 1

5.0e-15

70.91

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Query:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI
        MAK  L+RF  ++S++LKMPN+HFLP+NIS KD   IVKFE DVYLPTDEPHGSI
Subjt:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI

P53763 Uricase-2

1.7e-15

74.55

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Query:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI
        MAK  L+RF  ++ V LKMPNLHFLP+NIS+KD   IVKFEDDVYLPTDEPHGSI
Subjt:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI

Arabidopsis top hits

e value

%identity

Alignment

AT2G26230.1 uricase / urate oxidase / nodulin 35, putative

8.5e-18

70.91

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Query:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI
        M   VL RF  VSS+ LKMPN+HFLP+N+STK++ S+VKF+DDVYLPTDEPHGSI
Subjt:  MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI

Sequences

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CDS sequence

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ATGGCAAAGAATGTCCTCAGCAGGTTCCATGTTGTATCATCAGTGAGGTTGAAAATGCCAAATCTCCACTTCTTACCTATCAACATATCAACAAAAGATCATCGAAGTAT
CGTTAAGTTTGAGGATGATGTGTATCTGCCAACAGATGAACCCCATGGATCAATTTAA

mRNA sequence

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ATGGCAAAGAATGTCCTCAGCAGGTTCCATGTTGTATCATCAGTGAGGTTGAAAATGCCAAATCTCCACTTCTTACCTATCAACATATCAACAAAAGATCATCGAAGTAT
CGTTAAGTTTGAGGATGATGTGTATCTGCCAACAGATGAACCCCATGGATCAATTTAA

Protein sequence

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MAKNVLSRFHVVSSVRLKMPNLHFLPINISTKDHRSIVKFEDDVYLPTDEPHGSI

Tan0017574 (gene) of Snake gourd v1 genome