CuGenDBv2

Gene ID	Tan0022118
Organism	Trichosanthes anguina (Snake gourd v1)
Description	dCTP pyrophosphatase 1
Genome location	LG09:71197578..71199896
RNA-Seq Expression	Tan0022118
Synteny	Tan0022118
Gene Ontology terms	GO:0006253 - dCTP catabolic process (biological process) GO:0042262 - DNA protection (biological process) GO:0005829 - cytosol (cellular component) GO:0000287 - magnesium ion binding (molecular function) GO:0047840 - dCTP diphosphatase activity (molecular function)
InterPro domains	IPR025984 - dCTP pyrophosphatase 1

Homology

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GenBank top hits

e value

%identity

Alignment

XP_004138182.1 dCTP pyrophosphatase 1 [Cucumis sativus]

2.1e-61

96.8

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        ME+RSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVE+GLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKIVKNANKYPVAAFARALP
        GHAALSK+VKNANKYPVAAF RALP
Subjt:  GHAALSKIVKNANKYPVAAFARALP

XP_022921755.1 dCTP pyrophosphatase 1-like [Cucurbita moschata]

3.5e-61

96.8

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        ME+RSYEPEKTAKDVSLQELRD LAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVE+GLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKIVKNANKYPVAAFARALP
        GHAALSK+VKNANKYPVAAFARALP
Subjt:  GHAALSKIVKNANKYPVAAFARALP

XP_022933743.1 dCTP pyrophosphatase 1-like isoform X2 [Cucurbita moschata]

4.6e-61

96.8

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MESRSYEPEKTAKDVSL ELRDRLAEFA+VRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVE+GLPNWSAAEREHLEEE+SDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKIVKNANKYPVAAFARALP
        GHAALSKIVKNANKYPVAAFARALP
Subjt:  GHAALSKIVKNANKYPVAAFARALP

XP_022987438.1 dCTP pyrophosphatase 1-like [Cucurbita maxima]

1.3e-60

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        ME+RSYEPEKTAKDVSLQELRD L EFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVE+GLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKIVKNANKYPVAAFARALP
        GHAALSK+VKNANKYPVAAFARALP
Subjt:  GHAALSKIVKNANKYPVAAFARALP

XP_038880679.1 dCTP pyrophosphatase 1-like [Benincasa hispida]

1.2e-61

97.6

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MES SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVE+GLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKIVKNANKYPVAAFARALP
        GHAALSK+VKNANKYPVAAFARALP
Subjt:  GHAALSKIVKNANKYPVAAFARALP

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LP76 dCTP pyrophosphatase 1

9.9e-62

96.8

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        ME+RSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVE+GLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKIVKNANKYPVAAFARALP
        GHAALSK+VKNANKYPVAAF RALP
Subjt:  GHAALSKIVKNANKYPVAAFARALP

A0A5A7UWT3 dCTP pyrophosphatase 1

1.1e-60

95.2

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        ME+RSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVE+GLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKIVKNANKYPVAAFARALP
        GHAA+SK+VKNANKYPVAA  RALP
Subjt:  GHAALSKIVKNANKYPVAAFARALP

A0A6J1E6P9 dCTP pyrophosphatase 1

1.7e-61

96.8

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        ME+RSYEPEKTAKDVSLQELRD LAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVE+GLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKIVKNANKYPVAAFARALP
        GHAALSK+VKNANKYPVAAFARALP
Subjt:  GHAALSKIVKNANKYPVAAFARALP

A0A6J1F5P6 dCTP pyrophosphatase 1

2.2e-61

96.8

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MESRSYEPEKTAKDVSL ELRDRLAEFA+VRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVE+GLPNWSAAEREHLEEE+SDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKIVKNANKYPVAAFARALP
        GHAALSKIVKNANKYPVAAFARALP
Subjt:  GHAALSKIVKNANKYPVAAFARALP

A0A6J1JJF8 dCTP pyrophosphatase 1

6.4e-61

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        ME+RSYEPEKTAKDVSLQELRD L EFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVE+GLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKIVKNANKYPVAAFARALP
        GHAALSK+VKNANKYPVAAFARALP
Subjt:  GHAALSKIVKNANKYPVAAFARALP

SwissProt top hits

e value

%identity

Alignment

Q32KY6 dCTP pyrophosphatase 1

3.8e-26

53.64

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Query:  PEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAALSK
        P   + + +L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   WS  ER  L+EE+SD+L+YLV LA  C +DL  A L K
Subjt:  PEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAALSK

Query:  IVKNANKYPV
        +  N  +YPV
Subjt:  IVKNANKYPV

Q91VC0 dCTP pyrophosphatase 1

7.7e-27

54.87

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Query:  SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAA
        S+ PE T     L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   W   ER  L+EE+SDVL+YLV LA  C +DL  A 
Subjt:  SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAA

Query:  LSKIVKNANKYPV
        +SK+  N  +YPV
Subjt:  LSKIVKNANKYPV

Q9H773 dCTP pyrophosphatase 1

3.8e-26

56.25

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Query:  SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAA
        S+ PE T     L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   WS  ER  L+EE+SDVL+YLV LA  C +DL  A 
Subjt:  SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAA

Query:  LSKIVKNANKYP
        LSK+  N  +YP
Subjt:  LSKIVKNANKYP

Q9QY93 dCTP pyrophosphatase 1

5.9e-27

51.72

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Query:  ESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLG
        +S +  P + + + +L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   W   ER  L+EE+SDVL+YLV LA  C +DL 
Subjt:  ESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLG

Query:  HAALSKIVKNANKYPV
         A +SK+  N  +YPV
Subjt:  HAALSKIVKNANKYPV

Arabidopsis top hits

e value

%identity

Alignment

AT3G25400.1 CONTAINS InterPro DOMAIN/s: NTP Pyrophosphohydrolase MazG-related, RS21-C6 (InterPro:IPR011394), EAR (InterPro:IPR009039), NTP pyrophosphohydrolase MazG, putative catalytic core (InterPro:IPR004518); Has 1123 Blast hits to 1121 proteins in 452 species: Archae - 22; Bacteria - 753; Metazoa - 81; Fungi - 3; Plants - 83; Viruses - 0; Other Eukaryotes - 181 (source: NCBI BLink).

6.4e-37

69.9

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Query:  VSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAALSKIVKNANK
        VSLQ L  ++ +FA+ R WE+YHSPRNLLLA+VGEVGELSEIFQWKGEV +G P+W   E+ HL EE+SDVLLYLVRL+D CG+DLG AAL KI  NA K
Subjt:  VSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAALSKIVKNANK

Query:  YPV
        YPV
Subjt:  YPV

Sequences

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CDS sequence

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ATGGAGAGTCGTTCTTACGAACCTGAGAAAACCGCCAAAGACGTCTCACTGCAAGAACTCAGAGACAGGCTCGCAGAGTTCGCTCGAGTGCGAGGATGGGAACAATACCA
CAGCCCTAGAAACCTGCTCCTAGCACTTGTTGGCGAGGTCGGAGAGCTATCGGAGATATTCCAGTGGAAGGGAGAAGTGGAAAAAGGGCTGCCGAACTGGAGCGCGGCGG
AGAGAGAGCATTTGGAAGAAGAGGTGTCCGATGTGTTGCTCTATTTGGTGCGTCTCGCCGATGTGTGTGGCCTTGATCTCGGCCATGCCGCGCTCTCAAAGATCGTAAAA
AATGCGAACAAGTATCCTGTCGCCGCTTTCGCTCGCGCGCTGCCATGA

mRNA sequence

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AACCCCCCCCAACCCAACCCCGCTTATGTACATCTCTAGGTCAAACAATGTCTAGAAACTTTTAAAGTTCAATGGTTTATTAGATATACCATAAAAAAAATCTAAACACT
TGCTAAACACTTTTTATAATTTAGGAACTTATCAGCCCAACTCAAAAAATTTAGAAAGTAAACTTGTAAATATCCTAATAGTTAATGGTATTTTCGTGAATTAATCTACT
TTTTGAAACTGCTAATTTCTTTTGGCCCAGAAAAGTAGGTAGGAACAAAAGAATAAAAAAAAAAGATATGAAAAGAAGTAAAGGCCATGGTTGGGGAGATAGAGGATGAT
GAAATGAAAGAAAAGAATGGGATGGGTGTTTTGTTTAGGTGCTAGGAAAAGGGAAAATGAGATAAATTTACTTTTCTCAACAGAATTTGTCTGTTTTTCGTTGTAAGCTT
CAAGATTTGTCATCAATTTCCCAGACTTCCATCGCAATTTCCGGGATTTGTATAACGTGCCTACATCTCCAGTTTCTCTCACTCCAGTCTTCACATCACTTCCTTTCTCT
TTCTCCATTATTTAATATTTATGAAGTTGAGAAAAAGGGATTAAAATAAAATTTTAAAGTAAATAAATTTAAAAAAAAAAAAAACTAAACTATAATGATCTTGAGTTGAG
TCATAGGGGTCGTAAAGAACCGCCCCTCCAACTCCTAAATTTACGAAATTGTTGGAACTTTGTGAGTCGTAACTTTTTCACAAACCATCATTTAACATTTAACTACAAAC
ATCGTATAAGTTCAATTTTAAACCATATTCAAATCTTTACCATAAAGGTTTAAGAGCAGTTCGGCGATTCTTATCTCTCAGTGATAGTTTTTAGTTTCGAGCTTTTGAAA
AATAAAACTATTTGGAAACTGTTTTTGTTTCTCATTTTTTTCATAAACATTACAAGAATCAAGAAATGAAAATGTTATCGAAAGGACCTTAGAGTTTAAAAGTGCTTAAA
AGACTATTAATCAAACACTTGAAGGAAAACATTATTCTACAAGTGCTTTTTCAACAATCACTTTTAGGGATATCTTTTACTTTCTTCATTTACTTTAGCACGACAGAAAG
ACATGTTTTAGCCCACCTAATTAAAAGTACTTTCAAATATAGCCTAAAGTTAACCTAGAATATTACAGGACAAACATATAATTGAACTAGAAACAAAGGGGTCTGAAAGT
CACAAGCTTCAAATTCAAAAGCTTGAAAGAAGAGGATGAGTATTTTGTGGTATAGAGAAGTGGAGAAACATGGCATGGCATGAGGTGCAGCAGCAGATAGGTGATTTGAA
GTGATGAATGGAAAGATGGAGACAAGTTTTCCCACACTTCACATGCCTTAATTTGCTGTTTTATCTTTTTATCAAACACCTCGAGTGCACATCCCACTATCATCATCAAA
TTCCCCTCTATCTATCACTCTTTCTCTCTCCCTAAACTGACTTCTATAAATTTATGGCCCAACCAAACGCAGAGATCACAAGCACAAGCAGAGAAAAACAGATCATAGAA
GAAAGCGAGAGAAATGGAGAGTCGTTCTTACGAACCTGAGAAAACCGCCAAAGACGTCTCACTGCAAGAACTCAGAGACAGGCTCGCAGAGTTCGCTCGAGTGCGAGGAT
GGGAACAATACCACAGCCCTAGAAACCTGCTCCTAGCACTTGTTGGCGAGGTCGGAGAGCTATCGGAGATATTCCAGTGGAAGGGAGAAGTGGAAAAAGGGCTGCCGAAC
TGGAGCGCGGCGGAGAGAGAGCATTTGGAAGAAGAGGTGTCCGATGTGTTGCTCTATTTGGTGCGTCTCGCCGATGTGTGTGGCCTTGATCTCGGCCATGCCGCGCTCTC
AAAGATCGTAAAAAATGCGAACAAGTATCCTGTCGCCGCTTTCGCTCGCGCGCTGCCATGAACTTCGCGCCTTCGCGGCCGATTTTGTGTTCGTTTTTTCTTCGTATTGA
TATCGACTGAGAACTCAGTTTAGTCGTAGTTGTCTTTTTTTTAGGGGTAATATTCTTGTTTTCAACTTCTTTGGAGAGAAATAATTCAAGAAAAGTTCTATGTCGTTTGG
ATGTACTAAAAAGAGTTGAAAGTTTGTATTTTAAATATGTTTTCAACTTATTATTCGGAATAAATAGCTTTTGAATTTGTATTATGAATAA

Protein sequence

Show/hide protein sequence

MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVEKGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAALSKIVK
NANKYPVAAFARALP

Tan0022118 (gene) of Snake gourd v1 genome